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J Immunol (2007) 178 (1): 1–2.

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PILLARS OF IMMUNOLOGY

The Birth of a Cell Type

Giorgio Trinchieri

J Immunol (2007) 178 (1): 3–4.

View articletitled, The Birth of a Cell Type

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Pillars Article: Identification of a Novel Cell Type in Peripheral Lymphoid Organs of Mice. I. Morphology, Quantitation, Tissue Distribution. J. Exp. Med. 1973. 137: 1142–1162.

Ralph M. Steinman; Zanvil A. Cohn

J Immunol (2007) 178 (1): 5–25.

View articletitled, Pillars Article: Identification of a Novel Cell Type in Peripheral Lymphoid Organs of Mice. I. Morphology, Quantitation, Tissue Distribution. <em>J. Exp. Med.</em> 1973. 137: 1142–1162.

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BRIEF REVIEWS

Roundtrip Ticket for Secretory IgA: Role in Mucosal Homeostasis?¹

Blaise Corthésy

J Immunol (2007) 178 (1): 27–32.

View articletitled, Roundtrip Ticket for Secretory IgA: Role in Mucosal Homeostasis?<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B ¹^²

Hathairat Thananchai; Geraldine Gillespie; Maureen P. Martin; Arman Bashirova; Nobuyo Yawata; Makoto Yawata; Philippa Easterbrook; Daniel W. McVicar; Katsumi Maenaka; Peter Parham; Mary Carrington; Tao Dong; Sarah Rowland-Jones

J Immunol (2007) 178 (1): 33–37.

View articletitled, Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune Encephalomyelitis ¹

Eugene D. Ponomarev; Leah P. Shriver; Katarzyna Maresz; Joao Pedras-Vasconcelos; Daniela Verthelyi; Bonnie N. Dittel

J Immunol (2007) 178 (1): 39–48.

View articletitled, GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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B Cell Lymphoma 10 Is Essential for FcεR-Mediated Degranulation and IL-6 Production in Mast Cells ¹

Yuhong Chen; Bhanu P. Pappu; Hu Zeng; Liquan Xue; Stephan W. Morris; Xin Lin; Renren Wen; Demin Wang

J Immunol (2007) 178 (1): 49–57.

View articletitled, B Cell Lymphoma 10 Is Essential for FcεR-Mediated Degranulation and IL-6 Production in Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Sensitivity of NK1.1-Negative NKT Cells to Transgenic BATF Defines a Role for Activator Protein-1 in the Expansion and Maturation of Immature NKT Cells in the Thymus ¹

Alfred J. Zullo; Kamel Benlagha; Albert Bendelac; Elizabeth J. Taparowsky

J Immunol (2007) 178 (1): 58–66.

View articletitled, Sensitivity of NK1.1-Negative NKT Cells to Transgenic BATF Defines a Role for Activator Protein-1 in the Expansion and Maturation of Immature NKT Cells in the Thymus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Memory Antibody Levels: The Role of Persisting Antigen versus Plasma Cell Life Span

Dominique Gatto; Stephen W. Martin; Juliana Bessa; Erica Pellicioli; Philippe Saudan; Heather J. Hinton; Martin F. Bachmann

J Immunol (2007) 178 (1): 67–76.

View articletitled, Regulation of Memory Antibody Levels: The Role of Persisting Antigen versus Plasma Cell Life Span

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Granulysin-Mediated Tumor Rejection in Transgenic Mice ¹

Lisa P. Huang; Shu-Chen Lyu; Carol Clayberger; Alan M. Krensky

J Immunol (2007) 178 (1): 77–84.

View articletitled, Granulysin-Mediated Tumor Rejection in Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tumor-Primed Human Natural Killer Cells Lyse NK-Resistant Tumor Targets: Evidence of a Two-Stage Process in Resting NK Cell Activation ¹

Janet North; Ismail Bakhsh; Chloe Marden; Hanna Pittman; Elena Addison; Cristina Navarrete; Robert Anderson; Mark W. Lowdell

J Immunol (2007) 178 (1): 85–94.

View articletitled, Tumor-Primed Human Natural Killer Cells Lyse NK-Resistant Tumor Targets: Evidence of a Two-Stage Process in Resting NK Cell Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Apoptotic Splenocytes Drive the Autoimmune Response to Poly(ADP-ribose) Polymerase 1 in a Murine Model of Lupus ¹

Thomas Grader-Beck; Livia Casciola-Rosen; Thomas J. Lang; Roman Puliaev; Antony Rosen; Charles S. Via

J Immunol (2007) 178 (1): 95–102.

View articletitled, Apoptotic Splenocytes Drive the Autoimmune Response to Poly(ADP-ribose) Polymerase 1 in a Murine Model of Lupus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Reactive Oxygen Species by Atm Is Essential for Proper Response to DNA Double-Strand Breaks in Lymphocytes ¹

Keisuke Ito; Keiyo Takubo; Fumio Arai; Hitoshi Satoh; Sahoko Matsuoka; Masako Ohmura; Kazuhito Naka; Masaki Azuma; Kana Miyamoto; Kentaro Hosokawa; Yasuo Ikeda; Tak W. Mak; Toshio Suda; Atsushi Hirao

J Immunol (2007) 178 (1): 103–110.

View articletitled, Regulation of Reactive Oxygen Species by <em>Atm</em> Is Essential for Proper Response to DNA Double-Strand Breaks in Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Spleen Tyrosine Kinase (Syk), a Novel Target of Curcumin, Is Required for B Lymphoma Growth ¹

Murali Gururajan; Trivikram Dasu; Seif Shahidain; C. Darrell Jennings; Darrell A. Robertson; Vivek M. Rangnekar; Subbarao Bondada

J Immunol (2007) 178 (1): 111–121.

View articletitled, Spleen Tyrosine Kinase (Syk), a Novel Target of Curcumin, Is Required for B Lymphoma Growth<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Activation of Type B T Cells after Protein Immunization Reveals Novel Pathways of In Vivo Presentation of Peptides ¹

Scott B. Lovitch; Thomas J. Esparza; George Schweitzer; Jeremy Herzog; Emil R. Unanue

J Immunol (2007) 178 (1): 122–133.

View articletitled, Activation of Type B T Cells after Protein Immunization Reveals Novel Pathways of In Vivo Presentation of Peptides<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Feedback Regulation of Murine Autoimmunity via Dominant Anti-Inflammatory Effects of Interferon γ ¹

Alfredo Minguela; Silvia Pastor; Wentao Mi; James A. Richardson; E. Sally Ward

J Immunol (2007) 178 (1): 134–144.

View articletitled, Feedback Regulation of Murine Autoimmunity via Dominant Anti-Inflammatory Effects of Interferon γ<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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1,25-Dihydroxyvitamin D₃ Selectively Modulates Tolerogenic Properties in Myeloid but Not Plasmacytoid Dendritic Cells ¹

Giuseppe Penna; Susana Amuchastegui; Nadia Giarratana; Kenn C. Daniel; Marisa Vulcano; Silvano Sozzani; Luciano Adorini

J Immunol (2007) 178 (1): 145–153.

View articletitled, 1,25-Dihydroxyvitamin D<sub>3</sub> Selectively Modulates Tolerogenic Properties in Myeloid but Not Plasmacytoid Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dectin-1 Interaction with Tetraspanin CD37 Inhibits IL-6 Production ¹

Friederike Meyer-Wentrup; Carl G. Figdor; Marleen Ansems; Peter Brossart; Mark D. Wright; Gosse J. Adema; Annemiek B. van Spriel

J Immunol (2007) 178 (1): 154–162.

View articletitled, Dectin-1 Interaction with Tetraspanin CD37 Inhibits IL-6 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Genetic Manipulation of CD74 in Mouse Strains of Different Backgrounds Can Result in Opposite Responses to Central Nervous System Injury

Hadas Schori; Ravid Shechter; Idit Shachar; Michal Schwartz

J Immunol (2007) 178 (1): 163–171.

View articletitled, Genetic Manipulation of CD74 in Mouse Strains of Different Backgrounds Can Result in Opposite Responses to Central Nervous System Injury

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Th3 Cells in Peripheral Tolerance. II. TGF-β-Transgenic Th3 Cells Rescue IL-2-Deficient Mice from Autoimmunity ¹

Yijun Carrier; Jing Yuan; Vijay K. Kuchroo; Howard L. Weiner

J Immunol (2007) 178 (1): 172–178.

View articletitled, Th3 Cells in Peripheral Tolerance. II. TGF-β-Transgenic Th3 Cells Rescue IL-2-Deficient Mice from Autoimmunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Th3 Cells in Peripheral Tolerance. I. Induction of Foxp3-Positive Regulatory T Cells by Th3 Cells Derived from TGF-β T Cell-Transgenic Mice ¹

Yijun Carrier; Jing Yuan; Vijay K. Kuchroo; Howard L. Weiner

J Immunol (2007) 178 (1): 179–185.

View articletitled, Th3 Cells in Peripheral Tolerance. I. Induction of Foxp3-Positive Regulatory T Cells by Th3 Cells Derived from TGF-β T Cell-Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Essential Roles of c-Rel in TLR-Induced IL-23 p19 Gene Expression in Dendritic Cells ¹

Ruaidhrí J. Carmody; Qingguo Ruan; Hsiou-Chi Liou; Youhai H. Chen

J Immunol (2007) 178 (1): 186–191.

View articletitled, Essential Roles of c-Rel in TLR-Induced <em>IL-23 p19</em> Gene Expression in Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Osteoprotegerin Reduces the Serum Level of Receptor Activator of NF-κB Ligand Derived from Osteoblasts ¹

Yuko Nakamichi; Nobuyuki Udagawa; Yasuhiro Kobayashi; Midrori Nakamura; Yohei Yamamoto; Teruhito Yamashita; Toshihide Mizoguchi; Masahiro Sato; Makio Mogi; Josef M. Penninger; Naoyuki Takahashi

J Immunol (2007) 178 (1): 192–200.

View articletitled, Osteoprotegerin Reduces the Serum Level of Receptor Activator of NF-κB Ligand Derived from Osteoblasts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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α₁β₁ Integrin⁺ and Regulatory Foxp3⁺ T Cells Constitute Two Functionally Distinct Human CD4⁺ T Cell Subsets Oppositely Modulated by TNFα Blockade ¹

Itamar Goldstein; Shomron Ben-Horin; Alexander Koltakov; Helly Chermoshnuk; Victor Polevoy; Yakov Berkun; Ninette Amariglio; Ilan Bank

J Immunol (2007) 178 (1): 201–210.

View articletitled, α<sub>1</sub>β<sub>1</sub> Integrin<sup>+</sup> and Regulatory Foxp3<sup>+</sup> T Cells Constitute Two Functionally Distinct Human CD4<sup>+</sup> T Cell Subsets Oppositely Modulated by TNFα Blockade<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN-γ Negatively Regulates CpG-Induced IL-10 in Bone Marrow-Derived Dendritic Cells ¹

Rafael R. Flores; Kelly A. Diggs; Lauren M. Tait; Penelope A. Morel

J Immunol (2007) 178 (1): 211–218.

View articletitled, IFN-γ Negatively Regulates CpG-Induced IL-10 in Bone Marrow-Derived Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Comparative Roles of IL-4, IL-13, and IL-4Rα in Dendritic Cell Maturation and CD4⁺ Th2 Cell Function ¹

Dianne C. Webb; Yeping Cai; Klaus I. Matthaei; Paul S. Foster

J Immunol (2007) 178 (1): 219–227.

View articletitled, Comparative Roles of IL-4, IL-13, and IL-4Rα in Dendritic Cell Maturation and CD4<sup>+</sup> Th2 Cell Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Role of the Intracellular Domain of IL-7 Receptor in T Cell Development ¹

Qiong Jiang; Jiaqiang Huang; Wen Qing Li; Tiziana Cavinato; Jonathan R. Keller; Scott K. Durum

J Immunol (2007) 178 (1): 228–234.

View articletitled, Role of the Intracellular Domain of IL-7 Receptor in T Cell Development<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Functional Polymorphism of the KIR3DL1/S1 Receptor on Human NK Cells ¹

Geraldine M. O’Connor; Kieran J. Guinan; Rodat T. Cunningham; Derek Middleton; Peter Parham; Clair M. Gardiner

J Immunol (2007) 178 (1): 235–241.

View articletitled, Functional Polymorphism of the KIR3DL1/S1 Receptor on Human NK Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production ¹

Dapeng Gong; Thomas R. Malek

J Immunol (2007) 178 (1): 242–252.

View articletitled, Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Multiple NF-κB and IFN Regulatory Factor Family Transcription Factors Regulate CCL19 Gene Expression in Human Monocyte-Derived Dendritic Cells ¹

Taija E. Pietilä; Ville Veckman; Anne Lehtonen; Rongtuan Lin; John Hiscott; Ilkka Julkunen

J Immunol (2007) 178 (1): 253–261.

View articletitled, Multiple NF-κB and IFN Regulatory Factor Family Transcription Factors Regulate CCL19 Gene Expression in Human Monocyte-Derived Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-7/STAT5 Cytokine Signaling Pathway Is Essential but Insufficient for Maintenance of Naive CD4 T Cell Survival in Peripheral Lymphoid Organs ¹

Yoh-ichi Seki; Jianying Yang; Mariko Okamoto; Shinya Tanaka; Ryo Goitsuka; Michael A. Farrar; Masato Kubo

J Immunol (2007) 178 (1): 262–270.

View articletitled, IL-7/STAT5 Cytokine Signaling Pathway Is Essential but Insufficient for Maintenance of Naive CD4 T Cell Survival in Peripheral Lymphoid Organs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-6 Produced by Dendritic Cells from Lupus-Prone Mice Inhibits CD4⁺CD25⁺ T Cell Regulatory Functions ¹

Suigui Wan; Changqing Xia; Laurence Morel

J Immunol (2007) 178 (1): 271–279.

View articletitled, IL-6 Produced by Dendritic Cells from Lupus-Prone Mice Inhibits CD4<sup>+</sup>CD25<sup>+</sup> T Cell Regulatory Functions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3⁺ Regulatory T Cells ¹

Matthew A. Burchill; Jianying Yang; Christine Vogtenhuber; Bruce R. Blazar; Michael A. Farrar

J Immunol (2007) 178 (1): 280–290.

View articletitled, IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3<sup>+</sup> Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD25⁺CD4⁺ Regulatory T Cell Migration Requires L-Selectin Expression: L-Selectin Transcriptional Regulation Balances Constitutive Receptor Turnover ¹

Guglielmo M. Venturi; Rochelle M. Conway; Douglas A. Steeber; Thomas F. Tedder

J Immunol (2007) 178 (1): 291–300.

View articletitled, CD25<sup>+</sup>CD4<sup>+</sup> Regulatory T Cell Migration Requires L-Selectin Expression: L-Selectin Transcriptional Regulation Balances Constitutive Receptor Turnover<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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FoxP3⁺ T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues ¹

Jee H. Lee; Seung G. Kang; Chang H. Kim

J Immunol (2007) 178 (1): 301–311.

View articletitled, FoxP3<sup>+</sup> T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Critical Role of Protein Kinase C-θ in Fas/Fas Ligand-Mediated Apoptosis ¹

Santhakumar Manicassamy; Zuoming Sun

J Immunol (2007) 178 (1): 312–319.

View articletitled, The Critical Role of Protein Kinase C-θ in Fas/Fas Ligand-Mediated Apoptosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Selective Survival of Naturally Occurring Human CD4⁺CD25⁺Foxp3⁺ Regulatory T Cells Cultured with Rapamycin ¹

Laura Strauss; Theresa L. Whiteside; Ashley Knights; Christoph Bergmann; Alexander Knuth; Alfred Zippelius

J Immunol (2007) 178 (1): 320–329.

View articletitled, Selective Survival of Naturally Occurring Human CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> Regulatory T Cells Cultured with Rapamycin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Loss of Src Homology Region 2 Domain-Containing Protein Tyrosine Phosphatase-1 Increases CD8⁺ T Cell-APC Conjugate Formation and Is Associated with Enhanced In Vivo CTL Function ¹

Jean G. Sathish; Garry Dolton; Frances G. LeRoy; R. James Matthews

J Immunol (2007) 178 (1): 330–337.

View articletitled, Loss of Src Homology Region 2 Domain-Containing Protein Tyrosine Phosphatase-1 Increases CD8<sup>+</sup> T Cell-APC Conjugate Formation and Is Associated with Enhanced In Vivo CTL Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mycobacterium leprae Inhibits Dendritic Cell Activation and Maturation ¹

Rose Ann Murray; Mahveen Ruby Siddiqui; Megan Mendillo; James Krahenbuhl; Gilla Kaplan

J Immunol (2007) 178 (1): 338–344.

View articletitled, <em>Mycobacterium leprae</em> Inhibits Dendritic Cell Activation and Maturation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Brahma-Related Gene 1-Dependent STAT3 Recruitment at IL-6-Inducible Genes ¹

Zuyao Ni; Rod Bremner

J Immunol (2007) 178 (1): 345–351.

View articletitled, Brahma-Related Gene 1-Dependent STAT3 Recruitment at IL-6-Inducible Genes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay ¹

Claire L. Harris; David M. Pettigrew; Susan M. Lea; B. Paul Morgan

J Immunol (2007) 178 (1): 352–359.

View articletitled, Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Essential Role of GATA Transcriptional Factors in the Activation of Mast Cells ¹

Akio Masuda; Katsunori Hashimoto; Toyoharu Yokoi; Takeshi Doi; Tatsuhiko Kodama; Hiroaki Kume; Kinji Ohno; Tetsuya Matsuguchi

J Immunol (2007) 178 (1): 360–368.

View articletitled, Essential Role of GATA Transcriptional Factors in the Activation of Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Critical Residues at the Ly49 Natural Killer Receptor’s Homodimer Interface Determine Functional Recognition of m157, a Mouse Cytomegalovirus MHC Class I-Like Protein ¹

Agnieszka Kielczewska; Hee-Seo Kim; Lewis L. Lanier; Nazzareno Dimasi; Silvia M. Vidal

J Immunol (2007) 178 (1): 369–377.

View articletitled, Critical Residues at the Ly49 Natural Killer Receptor’s Homodimer Interface Determine Functional Recognition of m157, a Mouse Cytomegalovirus MHC Class I-Like Protein<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Distinct and Shared Transcriptomes Are Regulated by Microphthalmia-Associated Transcription Factor Isoforms in Mast Cells ¹

Amir H. Shahlaee; Stephanie Brandal; Youl-Nam Lee; Chunfa Jie; Clifford M. Takemoto

J Immunol (2007) 178 (1): 378–388.

View articletitled, Distinct and Shared Transcriptomes Are Regulated by Microphthalmia-Associated Transcription Factor Isoforms in Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cross-Reactivity and 1.4-Å Crystal Structure of Malassezia sympodialis Thioredoxin (Mala s 13), a Member of a New Pan-Allergen Family ¹

Andreas Limacher; Andreas G. Glaser; Christa Meier; Peter Schmid-Grendelmeier; Sabine Zeller; Leonardo Scapozza; Reto Crameri

J Immunol (2007) 178 (1): 389–396.

View articletitled, Cross-Reactivity and 1.4-Å Crystal Structure of <em>Malassezia sympodialis</em> Thioredoxin (Mala s 13), a Member of a New Pan-Allergen Family<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

Lamprey TLRs with Properties Distinct from Those of the Variable Lymphocyte Receptors ¹

Akihiro Ishii; Aya Matsuo; Hirofumi Sawa; Tadayuki Tsujita; Kyoko Shida; Misako Matsumoto; Tsukasa Seya

J Immunol (2007) 178 (1): 397–406.

View articletitled, Lamprey TLRs with Properties Distinct from Those of the Variable Lymphocyte Receptors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-22 Participates in an Innate Anti-HIV-1 Host-Resistance Network through Acute-Phase Protein Induction ¹

Dorothée Missé; Hans Yssel; Daria Trabattoni; Christelle Oblet; Sergio Lo Caputo; Francesco Mazzotta; Jérome Pène; Jean-Paul Gonzalez; Mario Clerici; Francisco Veas

J Immunol (2007) 178 (1): 407–415.

View articletitled, IL-22 Participates in an Innate Anti-HIV-1 Host-Resistance Network through Acute-Phase Protein Induction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Leukocyte Degranulation by cGMP-Dependent Protein Kinase and Phosphoinositide 3-Kinase: Potential Roles in Phosphorylation of Target Membrane SNARE Complex Proteins in Rat Mast Cells ¹

Masakatsu Nanamori; Jia Chen; Xiaoping Du; Richard D. Ye

J Immunol (2007) 178 (1): 416–427.

View articletitled, Regulation of Leukocyte Degranulation by cGMP-Dependent Protein Kinase and Phosphoinositide 3-Kinase: Potential Roles in Phosphorylation of Target Membrane SNARE Complex Proteins in Rat Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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3D7-Derived Plasmodium falciparum Erythrocyte Membrane Protein 1 Is a Frequent Target of Naturally Acquired Antibodies Recognizing Protein Domains in a Particular Pattern Independent of Malaria Transmission Intensity ¹

Louise Joergensen; Lasse S. Vestergaard; Louise Turner; Pamela Magistrado; John P. Lusingu; Martha Lemnge; Thor G. Theander; Anja T. R. Jensen

J Immunol (2007) 178 (1): 428–435.

View articletitled, 3D7-Derived <em>Plasmodium falciparum</em> Erythrocyte Membrane Protein 1 Is a Frequent Target of Naturally Acquired Antibodies Recognizing Protein Domains in a Particular Pattern Independent of Malaria Transmission Intensity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

A Novel Function for Galectin-1 at the Crossroad of Innate and Adaptive Immunity: Galectin-1 Regulates Monocyte/Macrophage Physiology through a Nonapoptotic ERK-Dependent Pathway ¹

Paula Barrionuevo; Macarena Beigier-Bompadre; Juan M. Ilarregui; Marta A. Toscano; Germán A. Bianco; Martín A. Isturiz; Gabriel A. Rabinovich

J Immunol (2007) 178 (1): 436–445.

View articletitled, A Novel Function for Galectin-1 at the Crossroad of Innate and Adaptive Immunity: Galectin-1 Regulates Monocyte/Macrophage Physiology through a Nonapoptotic ERK-Dependent Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Opposite Regulation of IL-1β and Secreted IL-1 Receptor Antagonist Production by Phosphatidylinositide-3 Kinases in Human Monocytes Activated by Lipopolysaccharides or Contact with T Cells ¹

Nicolas Molnarfi; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger

J Immunol (2007) 178 (1): 446–454.

View articletitled, Opposite Regulation of IL-1β and Secreted IL-1 Receptor Antagonist Production by Phosphatidylinositide-3 Kinases in Human Monocytes Activated by Lipopolysaccharides or Contact with T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dysregulation of Src Family Kinases in Mast Cells from Epilepsy-Resistant ASK versus Epilepsy-Prone EL Mice ¹

Jiro Kitaura; Yuko Kawakami; Mari Maeda-Yamamoto; Vaclav Horejsi; Toshiaki Kawakami

J Immunol (2007) 178 (1): 455–462.

View articletitled, Dysregulation of Src Family Kinases in Mast Cells from Epilepsy-Resistant ASK versus Epilepsy-Prone EL Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Regulation of Cytokine Release and Leukocyte Migration by Lipopolysaccharide-Stimulated Primary Human Lung Alveolar Type II Epithelial Cells and Macrophages ¹

Andrew J. Thorley; Paul A. Ford; Mark A. Giembycz; Peter Goldstraw; Alan Young; Teresa D. Tetley

J Immunol (2007) 178 (1): 463–473.

View articletitled, Differential Regulation of Cytokine Release and Leukocyte Migration by Lipopolysaccharide-Stimulated Primary Human Lung Alveolar Type II Epithelial Cells and Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Net Effect of Costimulatory Blockers Is Dependent on the Subset and Activation Status of the Autoreactive T Cells ¹

Ping Zhang; Deming Sun; Yan Ke; Henry J. Kaplan; Hui Shao

J Immunol (2007) 178 (1): 474–479.

View articletitled, The Net Effect of Costimulatory Blockers Is Dependent on the Subset and Activation Status of the Autoreactive T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Critical Role of the Fc Receptor γ-Chain on APCs in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation ¹

Kenichi Kitamura; Katsuyuki Takeda; Toshiyuki Koya; Nobuaki Miyahara; Taku Kodama; Azzeddine Dakhama; Toshiyuki Takai; Atsushi Hirano; Mitsune Tanimoto; Mine Harada; Erwin W. Gelfand

J Immunol (2007) 178 (1): 480–488.

View articletitled, Critical Role of the Fc Receptor γ-Chain on APCs in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR3-Mediated Synthesis and Release of Eotaxin-1/CCL11 from Human Bronchial Smooth Muscle Cells Stimulated with Double-Stranded RNA ¹

Kyoko Niimi; Koichiro Asano; Yoshiki Shiraishi; Takeshi Nakajima; Misa Wakaki; Junko Kagyo; Takahisa Takihara; Yusuke Suzuki; Koichi Fukunaga; Tetsuya Shiomi; Tsuyoshi Oguma; Koichi Sayama; Kazuhiro Yamaguchi; Yukikazu Natori; Misako Matsumoto; Tsukasa Seya; Mutsuo Yamaya; Akitoshi Ishizaka

J Immunol (2007) 178 (1): 489–495.

View articletitled, TLR3-Mediated Synthesis and Release of <em>Eotaxin-1/CCL11</em> from Human Bronchial Smooth Muscle Cells Stimulated with Double-Stranded RNA<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Protectin D1 Is Generated in Asthma and Dampens Airway Inflammation and Hyperresponsiveness ¹

Bruce D. Levy; Payal Kohli; Katherine Gotlinger; Oliver Haworth; Song Hong; Shamsah Kazani; Elliot Israel; Kathleen J. Haley; Charles N. Serhan

J Immunol (2007) 178 (1): 496–502.

View articletitled, Protectin D1 Is Generated in Asthma and Dampens Airway Inflammation and Hyperresponsiveness<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Hepatitis B Virus Sensitizes Hepatocytes to TRAIL-Induced Apoptosis through Bax ¹

Xiaohong Liang; Yugang Liu; Qiu Zhang; Lifen Gao; Lihui Han; Chunhong Ma; Lining Zhang; Youhai H. Chen; Wensheng Sun

J Immunol (2007) 178 (1): 503–510.

View articletitled, Hepatitis B Virus Sensitizes Hepatocytes to TRAIL-Induced Apoptosis through Bax<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-13 Is Pivotal in the Fibro-Obliterative Process of Bronchiolitis Obliterans Syndrome ¹

Michael P. Keane; Brigitte N. Gomperts; Samuel Weigt; Ying Ying Xue; Marie D. Burdick; Hiromi Nakamura; David A. Zisman; Abbas Ardehali; Rajan Saggar; Joseph P. Lynch, III; Cory Hogaboam; Steven L. Kunkel; Nicholas W. Lukacs; David J. Ross; Michael J. Grusby; Robert M. Strieter; John A. Belperio

J Immunol (2007) 178 (1): 511–519.

View articletitled, IL-13 Is Pivotal in the Fibro-Obliterative Process of Bronchiolitis Obliterans Syndrome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cell Transmigration through Brain Microvessel Endothelium Is Regulated by MIP-1α Chemokine and Matrix Metalloproteinases ¹

Alla L. Zozulya; Emily Reinke; Dana C. Baiu; Jozsef Karman; Matyas Sandor; Zsuzsanna Fabry

J Immunol (2007) 178 (1): 520–529.

View articletitled, Dendritic Cell Transmigration through Brain Microvessel Endothelium Is Regulated by MIP-1α Chemokine and Matrix Metalloproteinases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fcγ Receptors ¹

Wilfredo Rodriguez; Carolyn Mold; Milena Kataranovski; Julie A. Hutt; Lorraine L. Marnell; J. Sjef Verbeek; Terry W. Du Clos

J Immunol (2007) 178 (1): 530–538.

View articletitled, C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fcγ Receptors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Urinary Bladder Epithelium Antigen Induces CD8⁺ T Cell Tolerance, Activation, and Autoimmune Response ¹

Wujiang Liu; David P. Evanoff; Xiaohong Chen; Yi Luo

J Immunol (2007) 178 (1): 539–546.

View articletitled, Urinary Bladder Epithelium Antigen Induces CD8<sup>+</sup> T Cell Tolerance, Activation, and Autoimmune Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

A Local Antigen-Driven Humoral Response Is Present in the Inflammatory Myopathies ¹

Elizabeth M. Bradshaw; Ana Orihuela; Shannon L. McArdel; Mohammad Salajegheh; Anthony A. Amato; David A. Hafler; Steven A. Greenberg; Kevin C. O’Connor

J Immunol (2007) 178 (1): 547–556.

View articletitled, A Local Antigen-Driven Humoral Response Is Present in the Inflammatory Myopathies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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B Cell Clonal Expansion and Somatic Hypermutation of Ig Variable Heavy Chain Genes in the Synovial Membrane of Patients with Osteoarthritis ¹

Reng-Rong Da; Yufen Qin; Dominique Baeten; Yiping Zhang

J Immunol (2007) 178 (1): 557–565.

View articletitled, B Cell Clonal Expansion and Somatic Hypermutation of Ig Variable Heavy Chain Genes in the Synovial Membrane of Patients with Osteoarthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-Testis Antigen, Brother of the Regulator of Imprinted Sites ¹

Anahit Ghochikyan; Mikayel Mkrtichyan; Dmitri Loukinov; Gregory Mamikonyan; Svetlana D. Pack; Nina Movsesyan; Thomas E. Ichim; David H. Cribbs; Victor V. Lobanenkov; Michael G. Agadjanyan

J Immunol (2007) 178 (1): 566–573.

View articletitled, Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-Testis Antigen, Brother of the Regulator of Imprinted Sites<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Prolonged, NK Cell-Mediated Antitumor Effects of Suicide Gene Therapy Combined with Monocyte Chemoattractant Protein-1 against Hepatocellular Carcinoma

Tomoya Tsuchiyama; Yasunari Nakamoto; Yoshio Sakai; Yohei Marukawa; Masaaki Kitahara; Naofumi Mukaida; Shuichi Kaneko

J Immunol (2007) 178 (1): 574–583.

View articletitled, Prolonged, NK Cell-Mediated Antitumor Effects of Suicide Gene Therapy Combined with Monocyte Chemoattractant Protein-1 against Hepatocellular Carcinoma

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Suppression of Skin Lesions by Transdermal Application of CpG-Oligodeoxynucleotides in NC/Nga Mice, a Model of Human Atopic Dermatitis ¹

Joe Inoue; Yukihiko Aramaki

J Immunol (2007) 178 (1): 584–591.

View articletitled, Suppression of Skin Lesions by Transdermal Application of CpG-Oligodeoxynucleotides in NC/Nga Mice, a Model of Human Atopic Dermatitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis ¹

Hooman Ranjbaran; Seth I. Sokol; Amy Gallo; Raymond E. Eid; Alexander O. Iakimov; Alessio D’Alessio; John R. Kapoor; Shamsuddin Akhtar; Christopher J. Howes; Mihaela Aslan; Steven Pfau; Jordan S. Pober; George Tellides

J Immunol (2007) 178 (1): 592–604.

View articletitled, An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Th1 and Type 1 Cytotoxic T Cells Dominate Responses in T-bet Overexpression Transgenic Mice That Develop Contact Dermatitis ¹

Kazusa Ishizaki; Akiko Yamada; Keigyou Yoh; Takako Nakano; Homare Shimohata; Atsuko Maeda; Yuki Fujioka; Naoki Morito; Yasuhiro Kawachi; Kazuko Shibuya; Fujio Otsuka; Akira Shibuya; Satoru Takahashi

J Immunol (2007) 178 (1): 605–612.

View articletitled, Th1 and Type 1 Cytotoxic T Cells Dominate Responses in T-bet Overexpression Transgenic Mice That Develop Contact Dermatitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Streptococcal Preparation OK-432 Promotes Fusion Efficiency and Enhances Induction of Antigen-Specific CTL by Fusions of Dendritic Cells and Colorectal Cancer Cells ¹

Shigeo Koido; Eiichi Hara; Sadamu Homma; Akira Torii; Makoto Mitsunaga; Satoru Yanagisawa; Yoichi Toyama; Hidejiro Kawahara; Michiaki Watanabe; Seiya Yoshida; Susumu Kobayashi; Katsuhiko Yanaga; Kiyotaka Fujise; Hisao Tajiri

J Immunol (2007) 178 (1): 613–622.

View articletitled, Streptococcal Preparation OK-432 Promotes Fusion Efficiency and Enhances Induction of Antigen-Specific CTL by Fusions of Dendritic Cells and Colorectal Cancer Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cover Image

Cover Image

On the cover: Immunostaining of occludin (red) on brain capillary endothelial cells (BCEC) cocultured with GFP-dendritic cells (DC) (green). An MIP-1α-induced deep invasion of GFP-DC into BCEC monolayer can be prevented by MMP inhibitor resulting in improved occludin distribution and suggesting an importance of MMPs during DC traffic in the CNS. Zozulya, A. L., E. Reinke, D. C. Baiu, J. Karman, M. Sandor, and Z. Fabry. 2007. Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1α chemokine and matrix metalloproteinases. J. Immunol. 178: 520–529.
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