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J Immunol (2007) 178 (11): 6673–6674.

View articletitled, IN THIS ISSUE

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PILLARS OF IMMUNOLOGY

Controlling the Ir Genes

Jeremy M. Boss

J Immunol (2007) 178 (11): 6675–6676.

View articletitled, Controlling the Ir Genes

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Pillars Article: Complementation Cloning of an MHC Class II Transactivator Mutated in Hereditary MHC Class II Deficiency (or Bare Lymphocyte Syndrome). Cell 1993. 75: 135–146.

Viktor Steimle; Luc A. Otten; Madeleine Zufferey; Bernard Mach

J Immunol (2007) 178 (11): 6677–6688.

View articletitled, Pillars Article: Complementation Cloning of an MHC Class II Transactivator Mutated in Hereditary MHC Class II Deficiency (or Bare Lymphocyte Syndrome). <em>Cell</em> 1993. 75: 135–146.

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BRIEF REVIEWS

Telomerase in T Lymphocytes: Use It and Lose It?¹

Arne N. Akbar; Milica Vukmanovic-Stejic

J Immunol (2007) 178 (11): 6689–6694.

View articletitled, Telomerase in T Lymphocytes: Use It and Lose It?<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: CNS CD11c⁺ Cells from Mice with Encephalomyelitis Polarize Th17 cells and Support CD25⁺CD4⁺ T cell-Mediated Immunosuppression, Suggesting Dual Roles in the Disease Process ¹

Pratima Deshpande; Irah L. King; Benjamin M. Segal

J Immunol (2007) 178 (11): 6695–6699.

View articletitled, Cutting Edge: CNS CD11c<sup>+</sup> Cells from Mice with Encephalomyelitis Polarize Th17 cells and Support CD25<sup>+</sup>CD4<sup>+</sup> T cell-Mediated Immunosuppression, Suggesting Dual Roles in the Disease Process<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Small Molecule CD40 Ligand Mimetics Promote Control of Parasitemia and Enhance T Cells Producing IFN-γ during Experimental Trypanosoma cruzi Infection ¹

Mohammed Habib; Magali Noval Rivas; Mustapha Chamekh; Sébastien Wieckowski; Weimin Sun; Alberto Bianco; Nathalie Trouche; Olivier Chaloin; Hélène Dumortier; Michel Goldman; Gilles Guichard; Sylvie Fournel; Bernard Vray

J Immunol (2007) 178 (11): 6700–6704.

View articletitled, Cutting Edge: Small Molecule CD40 Ligand Mimetics Promote Control of Parasitemia and Enhance T Cells Producing IFN-γ during Experimental <em>Trypanosoma cruzi</em> Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Involvement of the Type I IFN Production and Signaling Pathway in Lipopolysaccharide-Induced IL-10 Production ¹

Elmer Y. Chang; Beichu Guo; Sean E. Doyle; Genhong Cheng

J Immunol (2007) 178 (11): 6705–6709.

View articletitled, Cutting Edge: Involvement of the Type I IFN Production and Signaling Pathway in Lipopolysaccharide-Induced IL-10 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Cross-Regulation by TLR4 and T cell Ig Mucin-3 Determines Sex Differences in Inflammatory Heart Disease ¹

Sylvia Frisancho-Kiss; Sarah E. Davis; Jennifer F. Nyland; J. Augusto Frisancho; Daniela Cihakova; Masheka A. Barrett; Noel R. Rose; DeLisa Fairweather

J Immunol (2007) 178 (11): 6710–6714.

View articletitled, Cutting Edge: Cross-Regulation by TLR4 and T cell Ig Mucin-3 Determines Sex Differences in Inflammatory Heart Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: TLR2 Directly Triggers Th1 Effector Functions ¹

Takayuki Imanishi; Hiromitsu Hara; Shinobu Suzuki; Nobutaka Suzuki; Shizuo Akira; Takashi Saito

J Immunol (2007) 178 (11): 6715–6719.

View articletitled, Cutting Edge: TLR2 Directly Triggers Th1 Effector Functions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Direct Action of Thymic Stromal Lymphopoietin on Activated Human CD4⁺ T Cells

Irina Rochman; Norihiko Watanabe; Kazuhiko Arima; Yong-Jun Liu; Warren J. Leonard

J Immunol (2007) 178 (11): 6720–6724.

View articletitled, Cutting Edge: Direct Action of Thymic Stromal Lymphopoietin on Activated Human CD4<sup>+</sup> T Cells

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Cutting Edge: Regulatory T Cells Induce CD4⁺CD25⁻Foxp3⁻ T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β

LiLi Xu; Atsushi Kitani; Ivan Fuss; Warren Strober

J Immunol (2007) 178 (11): 6725–6729.

View articletitled, Cutting Edge: Regulatory T Cells Induce CD4<sup>+</sup>CD25<sup>−</sup>Foxp3<sup>−</sup> T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β

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Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment ¹

Ilona Kryczek; Shuang Wei; Linhua Zou; Saleh Altuwaijri; Wojciech Szeliga; Jay Kolls; Alfred Chang; Weiping Zou

J Immunol (2007) 178 (11): 6730–6733.

View articletitled, Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

An Essential Role for TNF in Modulating Thresholds for Survival, Activation, and Tolerance of CD8⁺ T Cells ¹

Ioannis Chatzidakis; Georgia Fousteri; Debbie Tsoukatou; George Kollias; Clio Mamalaki

J Immunol (2007) 178 (11): 6735–6745.

View articletitled, An Essential Role for TNF in Modulating Thresholds for Survival, Activation, and Tolerance of CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike ¹

Anne Wilson; Denis-Luc Ardiet; Catherine Saner; Nathalie Vilain; Friedrich Beermann; Michel Aguet; H. Robson MacDonald; Olav Zilian

J Immunol (2007) 178 (11): 6746–6751.

View articletitled, Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Signal 3 Availability Limits the CD8 T Cell Response to a Solid Tumor ¹

Julie M. Curtsinger; Michael Y. Gerner; Debra C. Lins; Matthew F. Mescher

J Immunol (2007) 178 (11): 6752–6760.

View articletitled, Signal 3 Availability Limits the CD8 T Cell Response to a Solid Tumor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Comparative Prime-Boost Vaccinations Using Semliki Forest Virus, Adenovirus, and ALVAC Vectors Demonstrate Differences in the Generation of a Protective Central Memory CTL Response against the P815 Tumor ¹

Tanja I. Näslund; Catherine Uyttenhove; Eva K. L. Nordström; Didier Colau; Guy Warnier; Mikael Jondal; Benoı̂t J. Van den Eynde; Peter Liljeström

J Immunol (2007) 178 (11): 6761–6769.

View articletitled, Comparative Prime-Boost Vaccinations Using Semliki Forest Virus, Adenovirus, and ALVAC Vectors Demonstrate Differences in the Generation of a Protective Central Memory CTL Response against the P815 Tumor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lack of Essential Role of NF-κB p50, RelA, and cRel Subunits in Virus-Induced Type 1 IFN Expression ¹

Xingyu Wang; Sofia Hussain; Emilie-Jeanne Wang; Xiuyan Wang; Ming O. Li; Adolfo García-Sastre; Amer A. Beg

J Immunol (2007) 178 (11): 6770–6776.

View articletitled, Lack of Essential Role of NF-κB p50, RelA, and cRel Subunits in Virus-Induced Type 1 IFN Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Distinct Roles of Different NF-κB Subunits in Regulating Inflammatory and T Cell Stimulatory Gene Expression in Dendritic Cells ¹

Junmei Wang; Xingyu Wang; Sofia Hussain; Ye Zheng; Shomyseh Sanjabi; Fatah Ouaaz; Amer A. Beg

J Immunol (2007) 178 (11): 6777–6788.

View articletitled, Distinct Roles of Different NF-κB Subunits in Regulating Inflammatory and T Cell Stimulatory Gene Expression in Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Detection and Long-Term In Vivo Monitoring of Individual Tumor-Specific T Cell Clones in Patients with Metastatic Melanoma ¹

Jaroslav Michalek; Ivo Kocak; Vuk Fait; Jan Zaloudik; Roman Hajek

J Immunol (2007) 178 (11): 6789–6795.

View articletitled, Detection and Long-Term In Vivo Monitoring of Individual Tumor-Specific T Cell Clones in Patients with Metastatic Melanoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival ¹

John H. Carter; Juliet M. Lefebvre; David L. Wiest; Warren G. Tourtellotte

J Immunol (2007) 178 (11): 6796–6805.

View articletitled, Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Th17 Augmentation in OTII TCR Plus T Cell-Selective Type 1 Sphingosine 1-Phosphate Receptor Double Transgenic Mice ¹

Mei-Chuan Huang; Susan R. Watson; Jia-Jun Liao; Edward J. Goetzl

J Immunol (2007) 178 (11): 6806–6813.

View articletitled, Th17 Augmentation in OTII TCR Plus T Cell-Selective Type 1 Sphingosine 1-Phosphate Receptor Double Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Vaccinia Virus-Specific CD4⁺ T Cell Responses Target a Set of Antigens Largely Distinct from Those Targeted by CD8⁺ T Cell Responses ¹

Magdalini Moutaftsi; Huynh-Hoa Bui; Bjoern Peters; John Sidney; Shahram Salek-Ardakani; Carla Oseroff; Valerie Pasquetto; Shane Crotty; Michael Croft; Elliot J. Lefkowitz; Howard Grey; Alessandro Sette

J Immunol (2007) 178 (11): 6814–6820.

View articletitled, Vaccinia Virus-Specific CD4<sup>+</sup> T Cell Responses Target a Set of Antigens Largely Distinct from Those Targeted by CD8<sup>+</sup> T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Human CD5 Protects Circulating Tumor Antigen-Specific CTL from Tumor-Mediated Activation-Induced Cell Death ¹

Grzegorz Friedlein; Faten El Hage; Isabelle Vergnon; Catherine Richon; Patrick Saulnier; Yann Lécluse; Anne Caignard; Laurence Boumsell; Georges Bismuth; Salem Chouaib; Fathia Mami-Chouaib

J Immunol (2007) 178 (11): 6821–6827.

View articletitled, Human CD5 Protects Circulating Tumor Antigen-Specific CTL from Tumor-Mediated Activation-Induced Cell Death<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Cell Adhesion by Affinity and Conformational Unbending of α₄β₁ Integrin ¹

Alexandre Chigaev; Anna Waller; Gordon J. Zwartz; Tione Buranda; Larry A. Sklar

J Immunol (2007) 178 (11): 6828–6839.

View articletitled, Regulation of Cell Adhesion by Affinity and Conformational Unbending of α<sub>4</sub>β<sub>1</sub> Integrin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD4⁺CD25⁺ T Regulatory Cells Dominate Multiple Immune Evasion Mechanisms in Early but Not Late Phases of Tumor Development in a B Cell Lymphoma Model ¹

Kutlu G. Elpek; Chantale Lacelle; Narendra P. Singh; Esma S. Yolcu; Haval Shirwan

J Immunol (2007) 178 (11): 6840–6848.

View articletitled, CD4<sup>+</sup>CD25<sup>+</sup> T Regulatory Cells Dominate Multiple Immune Evasion Mechanisms in Early but Not Late Phases of Tumor Development in a B Cell Lymphoma Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Induction of Tolerance in CD8⁺ T Cells to a Transgenic Autoantigen Expressed in the Liver Does Not Require Cross-Presentation ¹

Junko Morimoto; Xiaoxio Tan; Ryan M. Teague; Claes Öhlén; Philip D. Greenberg

J Immunol (2007) 178 (11): 6849–6860.

View articletitled, Induction of Tolerance in CD8<sup>+</sup> T Cells to a Transgenic Autoantigen Expressed in the Liver Does Not Require Cross-Presentation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD103⁻ and CD103⁺ Bronchial Lymph Node Dendritic Cells Are Specialized in Presenting and Cross-Presenting Innocuous Antigen to CD4⁺ and CD8⁺ T Cells ¹

Maria-Luisa del Rio; Jose-Ignacio Rodriguez-Barbosa; Elisabeth Kremmer; Reinhold Förster

J Immunol (2007) 178 (11): 6861–6866.

View articletitled, CD103<sup>−</sup> and CD103<sup>+</sup> Bronchial Lymph Node Dendritic Cells Are Specialized in Presenting and Cross-Presenting Innocuous Antigen to CD4<sup>+</sup> and CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells ¹

Shaohua Yu; Cunren Liu; Kaihong Su; Jianhua Wang; Yuelong Liu; Liming Zhang; Chuanyu Li; Yingzi Cong; Robert Kimberly; William E. Grizzle; Carla Falkson; Huang-Ge Zhang

J Immunol (2007) 178 (11): 6867–6875.

View articletitled, Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Murine Dendritic Cell Type I IFN Production Induced by Human IgG-RNA Immune Complexes Is IFN Regulatory Factor (IRF)5 and IRF7 Dependent and Is Required for IL-6 Production ¹

Kei Yasuda; Christophe Richez; Joseph W. Maciaszek; Neerja Agrawal; Shizuo Akira; Ann Marshak-Rothstein; Ian R. Rifkin

J Immunol (2007) 178 (11): 6876–6885.

View articletitled, Murine Dendritic Cell Type I IFN Production Induced by Human IgG-RNA Immune Complexes Is IFN Regulatory Factor (IRF)5 and IRF7 Dependent and Is Required for IL-6 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Type 2 Diabetes Impairs Insulin Receptor Substrate-2-Mediated Phosphatidylinositol 3-Kinase Activity in Primary Macrophages to Induce a State of Cytokine Resistance to IL-4 in Association with Overexpression of Suppressor of Cytokine Signaling-3 ¹

Jason C. O’Connor; Christina L. Sherry; Christopher B. Guest; Gregory G. Freund

J Immunol (2007) 178 (11): 6886–6893.

View articletitled, Type 2 Diabetes Impairs Insulin Receptor Substrate-2-Mediated Phosphatidylinositol 3-Kinase Activity in Primary Macrophages to Induce a State of Cytokine Resistance to IL-4 in Association with Overexpression of Suppressor of Cytokine Signaling-3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The CD28/CTLA-4-B7 Signaling Pathway Is Involved in Both Allergic Sensitization and Tolerance Induction to Orally Administered Peanut Proteins

Femke van Wijk; Stefan Nierkens; Wilco de Jong; Ellen J. M. Wehrens; Louis Boon; Peter van Kooten; Léon M. J. Knippels; Raymond Pieters

J Immunol (2007) 178 (11): 6894–6900.

View articletitled, The CD28/CTLA-4-B7 Signaling Pathway Is Involved in Both Allergic Sensitization and Tolerance Induction to Orally Administered Peanut Proteins

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Distinct Subsets of FoxP3⁺ Regulatory T Cells Participate in the Control of Immune Responses ¹

Geoffrey L. Stephens; John Andersson; Ethan M. Shevach

J Immunol (2007) 178 (11): 6901–6911.

View articletitled, Distinct Subsets of FoxP3<sup>+</sup> Regulatory T Cells Participate in the Control of Immune Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Altered Innate Immune Functioning of Dendritic Cells in Elderly Humans: A Role of Phosphoinositide 3-Kinase-Signaling Pathway ¹

Anshu Agrawal; Sudhanshu Agrawal; Jia-Ning Cao; Houfen Su; Kathryn Osann; Sudhir Gupta

J Immunol (2007) 178 (11): 6912–6922.

View articletitled, Altered Innate Immune Functioning of Dendritic Cells in Elderly Humans: A Role of Phosphoinositide 3-Kinase-Signaling Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Analysis of the Role of Bleomycin Hydrolase in Antigen Presentation and the Generation of CD8 T Cell Responses ¹

Charles F. Towne; Ian A. York; Levi B. Watkin; John S. Lazo; Kenneth L. Rock

J Immunol (2007) 178 (11): 6923–6930.

View articletitled, Analysis of the Role of Bleomycin Hydrolase in Antigen Presentation and the Generation of CD8 T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Human Resting CD4⁺ T Cells Are Constitutively Inhibited by TGFβ under Steady-State Conditions ¹^²

Sabine Classen; Thomas Zander; Daniela Eggle; Jens M. Chemnitz; Benedikt Brors; Ingrid Büchmann; Alexey Popov; Marc Beyer; Roland Eils; Svenja Debey; Joachim L. Schultze

J Immunol (2007) 178 (11): 6931–6940.

View articletitled, Human Resting CD4<sup>+</sup> T Cells Are Constitutively Inhibited by TGFβ under Steady-State Conditions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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p300 Protein Acetyltransferase Activity Suppresses Systemic Lupus Erythematosus-Like Autoimmune Disease in Mice ¹

Nicole Forster; Sven Gallinat; Jadwiga Jablonska; Siegfried Weiss; Hans-Peter Elsässer; Werner Lutz

J Immunol (2007) 178 (11): 6941–6948.

View articletitled, p300 Protein Acetyltransferase Activity Suppresses Systemic Lupus Erythematosus-Like Autoimmune Disease in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Functional Gap Junctions Facilitate Melanoma Antigen Transfer and Cross-Presentation between Human Dendritic Cells ¹

Ariadna Mendoza-Naranjo; Pablo J. Saéz; C. Christian Johansson; Marcos Ramírez; Dinka Mandaković; Cristian Pereda; Mercedes N. López; Rolf Kiessling; Juan C. Sáez; Flavio Salazar-Onfray

J Immunol (2007) 178 (11): 6949–6957.

View articletitled, Functional Gap Junctions Facilitate Melanoma Antigen Transfer and Cross-Presentation between Human Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Parallel Loss of Myeloid and Plasmacytoid Dendritic Cells from Blood and Lymphoid Tissue in Simian AIDS ¹

Kevin N. Brown; Anita Trichel; Simon M. Barratt-Boyes

J Immunol (2007) 178 (11): 6958–6967.

View articletitled, Parallel Loss of Myeloid and Plasmacytoid Dendritic Cells from Blood and Lymphoid Tissue in Simian AIDS<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Role for CD21 in the Establishment of an Extracellular HIV Reservoir in Lymphoid Tissues ¹

Jason Ho; Susan Moir; Liudmila Kulik; Angela Malaspina; Eileen T. Donoghue; Natalie J. Miller; Wei Wang; Tae-Wook Chun; Anthony S. Fauci; V. Michael Holers

J Immunol (2007) 178 (11): 6968–6974.

View articletitled, Role for CD21 in the Establishment of an Extracellular HIV Reservoir in Lymphoid Tissues<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue ¹^²

Elizabeth Connick; Teresa Mattila; Joy M. Folkvord; Rick Schlichtemeier; Amie L. Meditz; M. Graham Ray; Martin D. McCarter; Samantha MaWhinney; Aaron Hage; Cara White; Pamela J. Skinner

J Immunol (2007) 178 (11): 6975–6983.

View articletitled, CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Nonobese Diabetic Mice ¹

Cicero Lee-Tian Chang; Shu-Lin Chang; Yi-Mei Lee; Yi-Ming Chiang; Da-Yung Chuang; Hui-Kai Kuo; Wen-Chin Yang

J Immunol (2007) 178 (11): 6984–6993.

View articletitled, Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Nonobese Diabetic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Role of Thrombospondin-1 in T Cell Response to Ocular Pigment Epithelial Cells ¹^²

Yuri Futagami; Sunao Sugita; Jose Vega; Kazuhiro Ishida; Hiroshi Takase; Kazuichi Maruyama; Hiroyuki Aburatani; Manabu Mochizuki

J Immunol (2007) 178 (11): 6994–7005.

View articletitled, Role of Thrombospondin-1 in T Cell Response to Ocular Pigment Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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In Vivo Signaling through the Neurokinin 1 Receptor Favors Transgene Expression by Langerhans Cells and Promotes the Generation of Th1- and Tc1-Biased Immune Responses ¹

Alicia R. Mathers; Olga A. Tckacheva; Brian M. Janelsins; William J. Shufesky; Adrian E. Morelli; Adriana T. Larregina

J Immunol (2007) 178 (11): 7006–7017.

View articletitled, In Vivo Signaling through the Neurokinin 1 Receptor Favors Transgene Expression by Langerhans Cells and Promotes the Generation of Th1- and Tc1-Biased Immune Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Rapamycin-Conditioned Dendritic Cells Are Poor Stimulators of Allogeneic CD4⁺ T Cells, but Enrich for Antigen-Specific Foxp3⁺ T Regulatory Cells and Promote Organ Transplant Tolerance ¹

Hēth R. Turnquist; Giorgio Raimondi; Alan F. Zahorchak; Ryan T. Fischer; Zhiliang Wang; Angus W. Thomson

J Immunol (2007) 178 (11): 7018–7031.

View articletitled, Rapamycin-Conditioned Dendritic Cells Are Poor Stimulators of Allogeneic CD4<sup>+</sup> T Cells, but Enrich for Antigen-Specific Foxp3<sup>+</sup> T Regulatory Cells and Promote Organ Transplant Tolerance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4⁺ T Cells ¹

Jamie Wong; Reinhard Obst; Margarida Correia-Neves; Grigoriy Losyev; Diane Mathis; Christophe Benoist

J Immunol (2007) 178 (11): 7032–7041.

View articletitled, Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-Deficient Mice ¹

Yoshitaka Taketomi; Kohei Sunaga; Satoshi Tanaka; Masanori Nakamura; Satoru Arata; Tomohiko Okuda; Tae-Chul Moon; Hyeun-Wook Chang; Yukihiko Sugimoto; Koichi Kokame; Toshiyuki Miyata; Makoto Murakami; Ichiro Kudo

J Immunol (2007) 178 (11): 7042–7053.

View articletitled, Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in <em>Ndrg1</em>-Deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Plasmodium berghei-Infected Primary Hepatocytes Process and Present the Circumsporozoite Protein to Specific CD8⁺ T Cells In Vitro ¹

Silayuv E. Bongfen; Ralph Torgler; Jackeline F. Romero; Laurent Renia; Giampietro Corradin

J Immunol (2007) 178 (11): 7054–7063.

View articletitled, <em>Plasmodium berghei</em>-Infected Primary Hepatocytes Process and Present the Circumsporozoite Protein to Specific CD8<sup>+</sup> T Cells In Vitro<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Tick Salivary Protein, Salp15, Inhibits the Development of Experimental Asthma ¹

Sara A. Paveglio; Jenna Allard; Jana Mayette; Laurie A. Whittaker; Ignacio Juncadella; Juan Anguita; Matthew E. Poynter

J Immunol (2007) 178 (11): 7064–7071.

View articletitled, The Tick Salivary Protein, Salp15, Inhibits the Development of Experimental Asthma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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C57BL/6 Mice Genetically Deficient in IL-12/IL-23 and IFN-γ Are Susceptible to Experimental Autoimmune Myasthenia Gravis, Suggesting a Pathogenic Role of Non-Th1 Cells ¹

Wei Wang; Monica Milani; Norma Ostlie; David Okita; Rajeev K. Agarwal; Rachel Caspi; Bianca M. Conti-Fine

J Immunol (2007) 178 (11): 7072–7080.

View articletitled, C57BL/6 Mice Genetically Deficient in IL-12/IL-23 and IFN-γ Are Susceptible to Experimental Autoimmune Myasthenia Gravis, Suggesting a Pathogenic Role of Non-Th1 Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Interaction of PRP4 with Krüppel-Like Factor 13 Regulates CCL5 Transcription ¹

Boli Huang; Yong-Tae Ahn; Lisa McPherson; Carol Clayberger; Alan M. Krensky

J Immunol (2007) 178 (11): 7081–7087.

View articletitled, Interaction of PRP4 with Krüppel-Like Factor 13 Regulates CCL5 Transcription<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Down-Regulation of the SWI/SNF Chromatin Remodeling Activity by TCR Signaling Is Required for Proper Thymocyte Maturation ¹

Kyoo Y. Lee; Young I. Choi; Jieun Kim; Jin W. Choi; Dong H. Sohn; Changjin Lee; Sung H. Jeon; Rho H. Seong

J Immunol (2007) 178 (11): 7088–7096.

View articletitled, Down-Regulation of the SWI/SNF Chromatin Remodeling Activity by TCR Signaling Is Required for Proper Thymocyte Maturation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-κB Transcription Factor c-Rel ¹

Karen Bunting; Sudha Rao; Kristine Hardy; Donna Woltring; Gareth S. Denyer; Jun Wang; Steve Gerondakis; M. Frances Shannon

J Immunol (2007) 178 (11): 7097–7109.

View articletitled, Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-κB Transcription Factor c-Rel<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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The Central Leucine-Rich Repeat Region of Chicken TLR16 Dictates Unique Ligand Specificity and Species-Specific Interaction with TLR2 ¹

A. Marijke Keestra; Marcel R. de Zoete; Rémon A. M. H. van Aubel; Jos P. M. van Putten

J Immunol (2007) 178 (11): 7110–7119.

View articletitled, The Central Leucine-Rich Repeat Region of Chicken TLR16 Dictates Unique Ligand Specificity and Species-Specific Interaction with TLR2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Novel Engineered Trastuzumab Conformational Epitopes Demonstrate In Vitro and In Vivo Antitumor Properties against HER-2/neu¹

Joan T. Garrett; Sharad Rawale; Stephanie D. Allen; Gary Phillips; Guido Forni; John C. Morris; Pravin T. P. Kaumaya

J Immunol (2007) 178 (11): 7120–7131.

View articletitled, Novel Engineered Trastuzumab Conformational Epitopes Demonstrate In Vitro and In Vivo Antitumor Properties against HER-2/<em>neu</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Neutralization Properties of a HIV-Specific Antibody Are Markedly Altered by Glycosylation Events Outside the Antigen-Binding Domain ¹

Luis R. Miranda; Mark Duval; Heather Doherty; Michael S. Seaman; Marshall R. Posner; Lisa A. Cavacini

J Immunol (2007) 178 (11): 7132–7138.

View articletitled, The Neutralization Properties of a HIV-Specific Antibody Are Markedly Altered by Glycosylation Events Outside the Antigen-Binding Domain<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Defining In Vivo Transcription Factor Complexes of the Murine CD21 and CD23 Genes ¹

Irina Debnath; Kirstin M. Roundy; Janis J. Weis; John H. Weis

J Immunol (2007) 178 (11): 7139–7150.

View articletitled, Defining In Vivo Transcription Factor Complexes of the Murine CD21 and CD23 Genes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

Genomics and Diversity of the Common Marmoset Monkey NK Complex ¹^²

Anne Averdam; Heiner Kuhl; Mario Sontag; Tamara Becker; Austin L. Hughes; Richard Reinhardt; Lutz Walter

J Immunol (2007) 178 (11): 7151–7161.

View articletitled, Genomics and Diversity of the Common Marmoset Monkey NK Complex<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

Supplementary data

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Extended Gene Map Reveals Tripartite Motif, C-Type Lectin, and Ig Superfamily Type Genes within a Subregion of the Chicken MHC-B Affecting Infectious Disease ¹^²

Takashi Shiina; W. Elwood Briles; Ronald M. Goto; Kazuyoshi Hosomichi; Kazuyo Yanagiya; Sayoko Shimizu; Hidetoshi Inoko; Marcia M. Miller

J Immunol (2007) 178 (11): 7162–7172.

View articletitled, Extended Gene Map Reveals Tripartite Motif, C-Type Lectin, and Ig Superfamily Type Genes within a Subregion of the Chicken <em>MHC</em>-<em>B</em> Affecting Infectious Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function

Qing-Guo Ruan; Kenneth Tung; Daniel Eisenman; Yulius Setiady; Sarah Eckenrode; Bing Yi; Sharad Purohit; Wei-Peng Zheng; Yan Zhang; Leena Peltonen; Jin-Xiong She

J Immunol (2007) 178 (11): 7173–7180.

View articletitled, The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function

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Cooperativity of Hydrophobic Anchor Interactions: Evidence for Epitope Selection by MHC Class II as a Folding Process ¹

Andrea Ferrante; Jack Gorski

J Immunol (2007) 178 (11): 7181–7189.

View articletitled, Cooperativity of Hydrophobic Anchor Interactions: Evidence for Epitope Selection by MHC Class II as a Folding Process<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

IFN-γ- and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-37 ¹

Adrian R. Martineau; Katalin A. Wilkinson; Sandra M. Newton; R. Andres Floto; Anthony W. Norman; Keira Skolimowska; Robert N. Davidson; Ole E. Sørensen; Beate Kampmann; Christopher J. Griffiths; Robert J. Wilkinson

J Immunol (2007) 178 (11): 7190–7198.

View articletitled, IFN-γ- and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-37<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tubulation of Class II MHC Compartments Is Microtubule Dependent and Involves Multiple Endolysosomal Membrane Proteins in Primary Dendritic Cells ¹

Jatin M. Vyas; You-Me Kim; Katerina Artavanis-Tsakonas; J. Christopher Love; Annemarthe G. Van der Veen; Hidde L. Ploegh

J Immunol (2007) 178 (11): 7199–7210.

View articletitled, Tubulation of Class II MHC Compartments Is Microtubule Dependent and Involves Multiple Endolysosomal Membrane Proteins in Primary Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel Functional CTL Avidity/Activity Compartmentalization to the Site of Mucosal Immunization Contributes to Protection of Macaques against Simian/Human Immunodeficiency Viral Depletion of Mucosal CD4⁺ T Cells

Igor M. Belyakov; Dmitry Isakov; Qing Zhu; Amiran Dzutsev; Jay A. Berzofsky

J Immunol (2007) 178 (11): 7211–7221.

View articletitled, A Novel Functional CTL Avidity/Activity Compartmentalization to the Site of Mucosal Immunization Contributes to Protection of Macaques against Simian/Human Immunodeficiency Viral Depletion of Mucosal CD4<sup>+</sup> T Cells

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B Cells Moderate Inflammatory Progression and Enhance Bacterial Containment upon Pulmonary Challenge with Mycobacterium tuberculosis¹

Paul J. Maglione; Jiayong Xu; John Chan

J Immunol (2007) 178 (11): 7222–7234.

View articletitled, B Cells Moderate Inflammatory Progression and Enhance Bacterial Containment upon Pulmonary Challenge with <em>Mycobacterium tuberculosis</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Viral Interference with Antigen Presentation Does Not Alter Acute or Chronic CD8 T Cell Immunodominance in Murine Cytomegalovirus Infection ¹

Michael W. Munks; Amelia K. Pinto; Carmen M. Doom; Ann B. Hill

J Immunol (2007) 178 (11): 7235–7241.

View articletitled, Viral Interference with Antigen Presentation Does Not Alter Acute or Chronic CD8 T Cell Immunodominance in Murine Cytomegalovirus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Biphasic Effect of Gingipains from Porphyromonas gingivalis on the Human Complement System ¹

Katarzyna Popadiak; Jan Potempa; Kristian Riesbeck; Anna M. Blom

J Immunol (2007) 178 (11): 7242–7250.

View articletitled, Biphasic Effect of Gingipains from <em>Porphyromonas gingivalis</em> on the Human Complement System<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cell-Derived IL-12p40 Homodimer Contributes to Susceptibility in Cutaneous Leishmaniasis in BALB/c Mice ¹

Axel P. Nigg; Sabine Zahn; Dominik Rückerl; Christoph Hölscher; Takayuki Yoshimoto; Jan M. Ehrchen; Florian Wölbing; Mark C. Udey; Esther von Stebut

J Immunol (2007) 178 (11): 7251–7258.

View articletitled, Dendritic Cell-Derived IL-12p40 Homodimer Contributes to Susceptibility in Cutaneous Leishmaniasis in BALB/c Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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STAT1 Expression in Dendritic Cells, but Not T Cells, Is Required for Immunity to Leishmania major¹

Leanne M. Johnson; Phillip Scott

J Immunol (2007) 178 (11): 7259–7266.

View articletitled, STAT1 Expression in Dendritic Cells, but Not T Cells, Is Required for Immunity to <em>Leishmania major</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Early Virus-Associated Bystander Events Affect the Fitness of the CD8 T Cell Response to Persistent Virus Infection ¹

Nicolas P. Andrews; Christopher D. Pack; Vaiva Vezys; Glen N. Barber; Aron E. Lukacher

J Immunol (2007) 178 (11): 7267–7275.

View articletitled, Early Virus-Associated Bystander Events Affect the Fitness of the CD8 T Cell Response to Persistent Virus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Integrin Engagement Mediates the Human Polymorphonuclear Leukocyte Response to a Fungal Pathogen-Associated Molecular Pattern ¹

Liz M. Lavigne; Xian M. O’Brien; Minsoo Kim; Jessie W. Janowski; Jorge E. Albina; Jonathan S. Reichner

J Immunol (2007) 178 (11): 7276–7282.

View articletitled, Integrin Engagement Mediates the Human Polymorphonuclear Leukocyte Response to a Fungal Pathogen-Associated Molecular Pattern<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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C-Reactive Protein Enhances Immunity to Streptococcus pneumoniae by Targeting Uptake to FcγR on Dendritic Cells ¹

Deirdre Thomas-Rudolph; Terry W. Du Clos; Clifford M. Snapper; Carolyn Mold

J Immunol (2007) 178 (11): 7283–7291.

View articletitled, C-Reactive Protein Enhances Immunity to <em>Streptococcus pneumoniae</em> by Targeting Uptake to FcγR on Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dual Binding Specificity of a Borrelia hermsii-Associated Complement Regulator-Acquiring Surface Protein for Factor H and Plasminogen Discloses a Putative Virulence Factor of Relapsing Fever Spirochetes ¹^²

Evelyn Rossmann; Peter Kraiczy; Pia Herzberger; Christine Skerka; Michael Kirschfink; Markus M. Simon; Peter F. Zipfel; Reinhard Wallich

J Immunol (2007) 178 (11): 7292–7301.

View articletitled, Dual Binding Specificity of a <em>Borrelia hermsii</em>-Associated Complement Regulator-Acquiring Surface Protein for Factor H and Plasminogen Discloses a Putative Virulence Factor of Relapsing Fever Spirochetes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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INFLAMMATION

A Novel RBP-Jκ-Dependent Switch from C/EBPβ to C/EBPζ at the C/EBP Binding Site on the C-Reactive Protein Promoter ¹

Prem Prakash Singh; Bhavya Voleti; Alok Agrawal

J Immunol (2007) 178 (11): 7302–7309.

View articletitled, A Novel RBP-Jκ-Dependent Switch from C/EBPβ to C/EBPζ at the C/EBP Binding Site on the C-Reactive Protein Promoter<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice ¹

Annie V. Le; Jae Youn Cho; Marina Miller; Shauna McElwain; Kirsti Golgotiu; David H. Broide

J Immunol (2007) 178 (11): 7310–7316.

View articletitled, Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Protection against Myocardial Ischemia/Reperfusion Injury in TLR4-Deficient Mice Is Mediated through a Phosphoinositide 3-Kinase-Dependent Mechanism ¹

Fang Hua; Tuanzhu Ha; Jing Ma; Yan Li; Jim Kelley; Xiang Gao; I. William Browder; Race L. Kao; David L. Williams; Chuanfu Li

J Immunol (2007) 178 (11): 7317–7324.

View articletitled, Protection against Myocardial Ischemia/Reperfusion Injury in TLR4-Deficient Mice Is Mediated through a Phosphoinositide 3-Kinase-Dependent Mechanism<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Soluble TNF-Like Cytokine (TL1A) Production by Immune Complexes Stimulated Monocytes in Rheumatoid Arthritis ¹

Marco A. Cassatella; Gabriela Pereira da Silva; Ilaria Tinazzi; Fabio Facchetti; Patrizia Scapini; Federica Calzetti; Nicola Tamassia; Ping Wei; Bernardetta Nardelli; Viktor Roschke; Annunciata Vecchi; Alberto Mantovani; Lisa M. Bambara; Steven W. Edwards; Antonio Carletto

J Immunol (2007) 178 (11): 7325–7333.

View articletitled, Soluble TNF-Like Cytokine (TL1A) Production by Immune Complexes Stimulated Monocytes in Rheumatoid Arthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Peroxynitrite-Dependent Pathway Is Responsible for Blood-Brain Barrier Permeability Changes during a Central Nervous System Inflammatory Response: TNF-α Is Neither Necessary nor Sufficient ¹

Timothy W. Phares; Marzena J. Fabis; Christine M. Brimer; Rhonda B. Kean; D. Craig Hooper

J Immunol (2007) 178 (11): 7334–7343.

View articletitled, A Peroxynitrite-Dependent Pathway Is Responsible for Blood-Brain Barrier Permeability Changes during a Central Nervous System Inflammatory Response: TNF-α Is Neither Necessary nor Sufficient<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The MYD88-Independent Pathway Is Not Mobilized in Human Neutrophils Stimulated via TLR4 ¹

Nicola Tamassia; Vincent Le Moigne; Federica Calzetti; Marta Donini; Sara Gasperini; Thornin Ear; Alexandre Cloutier; Fernando O. Martinez; Marco Fabbri; Massimo Locati; Alberto Mantovani; Patrick P. McDonald; Marco A. Cassatella

J Immunol (2007) 178 (11): 7344–7356.

View articletitled, The MYD88-Independent Pathway Is Not Mobilized in Human Neutrophils Stimulated via TLR4<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inactivation of Cdc42 Is Necessary for Depolymerization of Phagosomal F-Actin and Subsequent Phagosomal Maturation ¹

Maria Lerm; Veronika Patcha Brodin; Iida Ruishalme; Olle Stendahl; Eva Särndahl

J Immunol (2007) 178 (11): 7357–7365.

View articletitled, Inactivation of Cdc42 Is Necessary for Depolymerization of Phagosomal F-Actin and Subsequent Phagosomal Maturation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Corticosteroid Inhibition of Growth-Related Oncogene Protein-α via Mitogen-Activated Kinase Phosphatase-1 in Airway Smooth Muscle Cells ¹

Razao Issa; Shaoping Xie; Nadia Khorasani; Maria Sukkar; Ian M. Adcock; Kang-Yun Lee; Kian Fan Chung

J Immunol (2007) 178 (11): 7366–7375.

View articletitled, Corticosteroid Inhibition of Growth-Related Oncogene Protein-α via Mitogen-Activated Kinase Phosphatase-1 in Airway Smooth Muscle Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Nuclear Heat Shock Protein 72 as a Negative Regulator of Oxidative Stress (Hydrogen Peroxide)-Induced HMGB1 Cytoplasmic Translocation and Release ¹

Daolin Tang; Rui Kang; Weimin Xiao; Lei Jiang; Meidong Liu; Yongzhong Shi; Kangkai Wang; Haichao Wang; Xianzhong Xiao

J Immunol (2007) 178 (11): 7376–7384.

View articletitled, Nuclear Heat Shock Protein 72 as a Negative Regulator of Oxidative Stress (Hydrogen Peroxide)-Induced HMGB1 Cytoplasmic Translocation and Release<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN-γ Protects Cerulein-Induced Acute Pancreatitis by Repressing NF-κB Activation ¹

Takahito Hayashi; Yuko Ishida; Akihiko Kimura; Yoichiro Iwakura; Naofumi Mukaida; Toshikazu Kondo

J Immunol (2007) 178 (11): 7385–7394.

View articletitled, IFN-γ Protects Cerulein-Induced Acute Pancreatitis by Repressing NF-κB Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Proinflammatory Proteases Liberate a Discrete High-Affinity Functional FPRL1 (CCR12) Ligand from CCL23 ¹^²

Zhenhua Miao; Brett A. Premack; Zheng Wei; Yu Wang; Craig Gerard; Henry Showell; Maureen Howard; Thomas J. Schall; Robert Berahovich

J Immunol (2007) 178 (11): 7395–7404.

View articletitled, Proinflammatory Proteases Liberate a Discrete High-Affinity Functional FPRL1 (CCR12) Ligand from CCL23<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Expression of Tie-2 by Human Monocytes and Their Responses to Angiopoietin-2 ¹

Craig Murdoch; Simon Tazzyman; Steve Webster; Claire E. Lewis

J Immunol (2007) 178 (11): 7405–7411.

View articletitled, Expression of Tie-2 by Human Monocytes and Their Responses to Angiopoietin-2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Tubulin Is a Neuronal Target of Autoantibodies in Sydenham’s Chorea ¹

Christine A. Kirvan; Carol J. Cox; Susan E. Swedo; Madeleine W. Cunningham

J Immunol (2007) 178 (11): 7412–7421.

View articletitled, Tubulin Is a Neuronal Target of Autoantibodies in Sydenham’s Chorea<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Abrogation of Lupus Nephritis in Activation-Induced Deaminase-Deficient MRL/lpr Mice ¹

Chuancang Jiang; Julie Foley; Natasha Clayton; Grace Kissling; Micheal Jokinen; Ronald Herbert; Marilyn Diaz

J Immunol (2007) 178 (11): 7422–7431.

View articletitled, Abrogation of Lupus Nephritis in Activation-Induced Deaminase-Deficient MRL/lpr Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Soluble Ig-Like Transcript 3 Inhibits Tumor Allograft Rejection in Humanized SCID Mice and T Cell Responses in Cancer Patients ¹

J Immunol (2007) 178 (11): 7432–7441.

View articletitled, Soluble Ig-Like Transcript 3 Inhibits Tumor Allograft Rejection in Humanized SCID Mice and T Cell Responses in Cancer Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients ¹

Asifa S. Haider; Michelle A. Lowes; Humphrey Gardner; Raj Bandaru; Kamruz Darabi; Francesca Chamian; Toyoko Kikuchi; Patricia Gilleaudeau; Mary S. Whalen; Irma Cardinale; Inna Novitskaya; James G. Krueger

J Immunol (2007) 178 (11): 7442–7449.

View articletitled, Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-α Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis

Gunther Spohn; Reto Guler; Pål Johansen; Iris Keller; Muazzam Jacobs; Markus Beck; Franziska Rohner; Monika Bauer; Klaus Dietmeier; Thomas M. Kündig; Gary T. Jennings; Frank Brombacher; Martin F. Bachmann

J Immunol (2007) 178 (11): 7450–7457.

View articletitled, A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-α Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis

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Immunization of HLA Class I Transgenic Mice Identifies Autoantigenic Epitopes Eliciting Dominant Responses in Type 1 Diabetes Patients ¹

Philippe Blancou; Roberto Mallone; Emanuela Martinuzzi; Sabine Sévère; Sylvie Pogu; Giulia Novelli; Graziella Bruno; Bernard Charbonnel; Manuel Dolz; Lucy Chaillous; Peter van Endert; Jean-Marie Bach

J Immunol (2007) 178 (11): 7458–7466.

View articletitled, Immunization of HLA Class I Transgenic Mice Identifies Autoantigenic Epitopes Eliciting Dominant Responses in Type 1 Diabetes Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Comparing ELISA and Surface Plasmon Resonance for Assessing Clinical Immunogenicity of Panitumumab

James A. Lofgren; Sripriya Dhandapani; Jason J. Pennucci; Christina M. Abbott; Daniel T. Mytych; Arunan Kaliyaperumal; Steven J. Swanson; Michael C. Mullenix

J Immunol (2007) 178 (11): 7467–7472.

View articletitled, Comparing ELISA and Surface Plasmon Resonance for Assessing Clinical Immunogenicity of Panitumumab

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Enhanced Immune Reconstitution by Sex Steroid Ablation following Allogeneic Hemopoietic Stem Cell Transplantation ¹

Gabrielle L. Goldberg; Önder Alpdogan; Stephanie J. Muriglan; Maree V. Hammett; Morag K. Milton; Jeffrey M. Eng; Vanessa M. Hubbard; Adam Kochman; Lucy M. Willis; Andrew S. Greenberg; Kartono H. Tjoe; Jayne S. Sutherland; Ann Chidgey; Marcel R. M. van den Brink; Richard L. Boyd

J Immunol (2007) 178 (11): 7473–7484.

View articletitled, Enhanced Immune Reconstitution by Sex Steroid Ablation following Allogeneic Hemopoietic Stem Cell Transplantation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

Human mAbs to Pseudomonas aeruginosa alginate that protect against infection by both mucoid and nonmucoid strains.

G. B. Pier; D. Boyer; M. Preston; F. T. Coleman; N. Llosa; S. Mueschenborn-Koglin; C. Theilacker; H. Goldenberg; J. Uchin; G. P. Priebe; M. Grout; M. Posner; L. Cavacini

J Immunol (2007) 178 (11): 7485.

View articletitled, Human mAbs to <em>Pseudomonas aeruginosa</em> alginate that protect against infection by both mucoid and nonmucoid strains.

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TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis

H. J. Brown; H. R. Lock; S. H. Sacks; M. G. Robson

J Immunol (2007) 178 (11): 7485.

View articletitled, TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis

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Induced expression of murine γ 2a by CD40 ligation independently of IFN-γ

J. T. Collins; J. Shi; B. E. Burrell; D. K. Bishop; W. A. Dunnick

J Immunol (2007) 178 (11): 7486.

View articletitled, Induced expression of murine γ 2a by CD40 ligation independently of IFN-γ

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Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs

I.-J. Kim; C. E. Burkum; T. Cookenham; P. L. Schwartzberg; D. L. Woodland; M. A. Blackman

J Immunol (2007) 178 (11): 7487.

View articletitled, Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs

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The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis

S. M. Sa; P. A. Valdez; J. Wu; K. Jung; F. Zhong; L. Hall; I. Kasman; J. Winer; Z. Modrusan; D. M. Danilenko; W. Ouyang

J Immunol (2007) 178 (11): 7487.

View articletitled, The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis

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Human CD4⁺CD25^low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance

Q. Xu; J. Lee; E. Jankowska-Gan; J. Schultz; D. A. Roennburg; L. D. Haynes; S. Kusaka; H. W. Sollinger; S. J. Knechtle; A. M. VanBuskirk; J. R. Torrealba; W. J. Burlingham

J Immunol (2007) 178 (11): 7488.

View articletitled, Human CD4<sup>+</sup>CD25<sup>low</sup> adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance

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An essential role for IL-18 in CD8 T cell-mediated suppression of IgE responses

M. Salagianni; W. K. Loon; M. J. Thomas; A. Noble; D. M. Kemeny

J Immunol (2007) 178 (11): 7488.

View articletitled, An essential role for IL-18 in CD8 T cell-mediated suppression of IgE responses

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Cover Image

Cover Image

On the cover: Confocal microscopy of human airway smooth muscle cells in primary culture incubated with an antibody to glucocorticoid receptor (GR) showing nuclear translocation of GR after exposure to dexamethasone. Staining of nuclei with DAPI is in blue and positive GR staining is shown with Rhodamine red. Nuclei are now stained red as in cytoplasm. Issa, R., S. Xie, N. Khorasani, M. Sukkar, I. M. Adcock, K.-Y. Lee, and K. F. Chung. 2007. Corticosteroid inhibition of growth-related oncogene protein-α via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells. J. Immunol. 178: 7366–7375.
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