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J Immunol (2007) 178 (12): 7499–7500.

View articletitled, IN THIS ISSUE

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LETTERS TO THE EDITOR

Comment on “A Novel Pathway that Regulates Inflammatory Disease in the Respiratory Tract”

Chris L. Van Hove; Tania Maes; Guy F. Joos; Kurt G. Tournoy

J Immunol (2007) 178 (12): 7501.

View articletitled, Comment on “A Novel Pathway that Regulates Inflammatory Disease in the Respiratory Tract”

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Response to Comment on “A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract”

Naiqian Niu; Lauren Cohn

J Immunol (2007) 178 (12): 7501–7502.

View articletitled, Response to Comment on “A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract”

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BRIEF REVIEWS

The Innate Immune System in Allograft Rejection and Tolerance ¹

David F. LaRosa; Adeeb H. Rahman; Laurence A. Turka

J Immunol (2007) 178 (12): 7503–7509.

View articletitled, The Innate Immune System in Allograft Rejection and Tolerance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: Transitional T3 B Cells Do Not Give Rise to Mature B Cells, Have Undergone Selection, and Are Reduced in Murine Lupus ¹

Brittany N. Teague; Yujun Pan; Philip A. Mudd; Britt Nakken; Qingzhao Zhang; Peter Szodoray; Xana Kim-Howard; Patrick C. Wilson; A. Darise Farris

J Immunol (2007) 178 (12): 7511–7515.

View articletitled, Cutting Edge: Transitional T3 B Cells Do Not Give Rise to Mature B Cells, Have Undergone Selection, and Are Reduced in Murine Lupus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: Essential Role of Hypoxia Inducible Factor-1α in Development of Lipopolysaccharide-Induced Sepsis ¹

Carole Peyssonnaux; Pilar Cejudo-Martin; Andrew Doedens; Annelies S. Zinkernagel; Randall S. Johnson; Victor Nizet

J Immunol (2007) 178 (12): 7516–7519.

View articletitled, Cutting Edge: Essential Role of Hypoxia Inducible Factor-1α in Development of Lipopolysaccharide-Induced Sepsis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: A Common Polymorphism Impairs Cell Surface Trafficking and Functional Responses of TLR1 but Protects against Leprosy ¹

Christopher M. Johnson; Elizabeth A. Lyle; Katherine O. Omueti; Vitaly A. Stepensky; Olcay Yegin; Erkan Alpsoy; Lutz Hamann; Ralf R. Schumann; Richard I. Tapping

J Immunol (2007) 178 (12): 7520–7524.

View articletitled, Cutting Edge: A Common Polymorphism Impairs Cell Surface Trafficking and Functional Responses of TLR1 but Protects against Leprosy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Human Th17 Cells Are Identified as Bearing CCR2⁺CCR5⁻ Phenotype ¹

Wakiro Sato; Toshimasa Aranami; Takashi Yamamura

J Immunol (2007) 178 (12): 7525–7529.

View articletitled, Cutting Edge: Human Th17 Cells Are Identified as Bearing CCR2<sup>+</sup>CCR5<sup>−</sup> Phenotype<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

TLR Stimulation Modifies BLyS Receptor Expression in Follicular and Marginal Zone B Cells ¹

Laura S. Treml; Gianluca Carlesso; Kristen L. Hoek; Jason E. Stadanlick; Taku Kambayashi; Richard J. Bram; Michael P. Cancro; Wasif N. Khan

J Immunol (2007) 178 (12): 7531–7539.

View articletitled, TLR Stimulation Modifies BLyS Receptor Expression in Follicular and Marginal Zone B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Type I IFN Contributes to NK Cell Homeostasis, Activation, and Antitumor Function ¹

Jeremy B. Swann; Yoshihiro Hayakawa; Nadeen Zerafa; Kathleen C. F. Sheehan; Bernadette Scott; Robert D. Schreiber; Paul Hertzog; Mark J. Smyth

J Immunol (2007) 178 (12): 7540–7549.

View articletitled, Type I IFN Contributes to NK Cell Homeostasis, Activation, and Antitumor Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Agonist-Driven Development of CD4⁺CD25⁺Foxp3⁺ Regulatory T Cells Requires a Second Signal Mediated by Stat6 ¹

Vanesa Sanchez-Guajardo; Corinne Tanchot; John T. O’Malley; Mark H. Kaplan; Sylvie Garcia; Antonio A. Freitas

J Immunol (2007) 178 (12): 7550–7556.

View articletitled, Agonist-Driven Development of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> Regulatory T Cells Requires a Second Signal Mediated by Stat6<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Rates of Processing Determine the Immunogenicity of Immunoproteasome-Generated Epitopes ¹

Parampal Deol; Dietmar M. W. Zaiss; John J. Monaco; Alice J. A. M. Sijts

J Immunol (2007) 178 (12): 7557–7562.

View articletitled, Rates of Processing Determine the Immunogenicity of Immunoproteasome-Generated Epitopes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Persistent Depots of Influenza Antigen Fail To Induce a Cytotoxic CD8 T Cell Response ¹

Dawn M. Jelley-Gibbs; John P. Dibble; Deborah M. Brown; Tara M. Strutt; K. Kai McKinstry; Susan L. Swain

J Immunol (2007) 178 (12): 7563–7570.

View articletitled, Persistent Depots of Influenza Antigen Fail To Induce a Cytotoxic CD8 T Cell Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Systemic Administration of IL-23 Induces Potent Antitumor Immunity Primarily Mediated through Th1-Type Response in Association with the Endogenously Expressed IL-12 ¹

Teruo Kaiga; Marimo Sato; Hide Kaneda; Yoichiro Iwakura; Tadatoshi Takayama; Hideaki Tahara

J Immunol (2007) 178 (12): 7571–7580.

View articletitled, Systemic Administration of IL-23 Induces Potent Antitumor Immunity Primarily Mediated through Th1-Type Response in Association with the Endogenously Expressed IL-12<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8⁺ T Lymphocytes ¹

Nadine van Montfoort; Judith M. H. de Jong; Danita H. Schuurhuis; Ellen I. H. van der Voort; Marcel G. M. Camps; Tom W. J. Huizinga; Cees van Kooten; Mohamed R. Daha; J. Sjef Verbeek; Ferry Ossendorp; René E. M. Toes

J Immunol (2007) 178 (12): 7581–7586.

View articletitled, A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8<sup>+</sup> T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Uptake of Human Papillomavirus Virus-Like Particles by Dendritic Cells Is Mediated by Fcγ Receptors and Contributes to Acquisition of T Cell Immunity ¹

Diane M. Da Silva; Steven C. Fausch; J. Sjef Verbeek; W. Martin Kast

J Immunol (2007) 178 (12): 7587–7597.

View articletitled, Uptake of Human Papillomavirus Virus-Like Particles by Dendritic Cells Is Mediated by Fcγ Receptors and Contributes to Acquisition of T Cell Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Impaired Accumulation of Antigen-Specific CD8 Lymphocytes in Chemokine CCL25-Deficient Intestinal Epithelium and Lamina Propria ¹

Marc-André Wurbel; Marie Malissen; Delphine Guy-Grand; Bernard Malissen; James J. Campbell

J Immunol (2007) 178 (12): 7598–7606.

View articletitled, Impaired Accumulation of Antigen-Specific CD8 Lymphocytes in Chemokine CCL25-Deficient Intestinal Epithelium and Lamina Propria<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-27 Synthesis Induced by TLR Ligation Critically Depends on IFN Regulatory Factor 3 ¹

Céline Molle; Muriel Nguyen; Véronique Flamand; Joelle Renneson; François Trottein; Dominique De Wit; Fabienne Willems; Michel Goldman; Stanislas Goriely

J Immunol (2007) 178 (12): 7607–7615.

View articletitled, IL-27 Synthesis Induced by TLR Ligation Critically Depends on IFN Regulatory Factor 3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Disregulated Influenza A Virus-Specific CD8⁺ T Cell Homeostasis in the Absence of IFN-γ Signaling ¹

Stephen J. Turner; Elvia Olivas; Astrid Gutierrez; Gabriela Diaz; Peter C. Doherty

J Immunol (2007) 178 (12): 7616–7622.

View articletitled, Disregulated Influenza A Virus-Specific CD8<sup>+</sup> T Cell Homeostasis in the Absence of IFN-γ Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunomodulatory Mediators from Pollen Enhance the Migratory Capacity of Dendritic Cells and License Them for Th2 Attraction ¹

Valentina Mariani; Stefanie Gilles; Thilo Jakob; Martina Thiel; Martin J. Mueller; Johannes Ring; Heidrun Behrendt; Claudia Traidl-Hoffmann

J Immunol (2007) 178 (12): 7623–7631.

View articletitled, Immunomodulatory Mediators from Pollen Enhance the Migratory Capacity of Dendritic Cells and License Them for Th2 Attraction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Krüppel-Like Factor 2 Controls T Cell Trafficking by Activating L-Selectin (CD62L) and Sphingosine-1-Phosphate Receptor 1 Transcription ¹

Ailin Bai; Hui Hu; Mandy Yeung; Jianzhu Chen

J Immunol (2007) 178 (12): 7632–7639.

View articletitled, Krüppel-Like Factor 2 Controls T Cell Trafficking by Activating L-Selectin (CD62L) and Sphingosine-1-Phosphate Receptor 1 Transcription<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-21 Promotes Differentiation of Naive CD8 T Cells to a Unique Effector Phenotype ¹

Kerry A. Casey; Matthew F. Mescher

J Immunol (2007) 178 (12): 7640–7648.

View articletitled, IL-21 Promotes Differentiation of Naive CD8 T Cells to a Unique Effector Phenotype<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD8⁺ T Cell-Mediated Suppression of Autoimmunity in a Murine Lupus Model of Peptide-Induced Immune Tolerance Depends on Foxp3 Expression ¹

Ram Pyare Singh; Antonio La Cava; Maida Wong; Fanny Ebling; Bevra H. Hahn

J Immunol (2007) 178 (12): 7649–7657.

View articletitled, CD8<sup>+</sup> T Cell-Mediated Suppression of Autoimmunity in a Murine Lupus Model of Peptide-Induced Immune Tolerance Depends on Foxp3 Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells ¹

Galit Alter; Todd J. Suscovich; Nickolas Teigen; Angela Meier; Hendrik Streeck; Christian Brander; Marcus Altfeld

J Immunol (2007) 178 (12): 7658–7666.

View articletitled, Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Kinetic and Dynamic Analysis of Foxp3 Induced in T Cells by TGF-β ¹

Ramesh K. Selvaraj; Terrence L. Geiger

J Immunol (2007) 178 (12): 7667–7677.

View articletitled, A Kinetic and Dynamic Analysis of Foxp3 Induced in T Cells by TGF-β<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Down-Regulation of E-Cadherin in Human Bronchial Epithelial Cells Leads to Epidermal Growth Factor Receptor-Dependent Th2 Cell-Promoting Activity ¹

Irene H. Heijink; P. Marcel Kies; Henk F. Kauffman; Dirkje S. Postma; Antoon J. M. van Oosterhout; Edo Vellenga

J Immunol (2007) 178 (12): 7678–7685.

View articletitled, Down-Regulation of E-Cadherin in Human Bronchial Epithelial Cells Leads to Epidermal Growth Factor Receptor-Dependent Th2 Cell-Promoting Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Acute Alcohol Exposure Exerts Anti-Inflammatory Effects by Inhibiting IκB Kinase Activity and p65 Phosphorylation in Human Monocytes ¹

Pranoti Mandrekar; Valentina Jeliazkova; Donna Catalano; Gyongyi Szabo

J Immunol (2007) 178 (12): 7686–7693.

View articletitled, Acute Alcohol Exposure Exerts Anti-Inflammatory Effects by Inhibiting IκB Kinase Activity and p65 Phosphorylation in Human Monocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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OX40-Mediated Differentiation to Effector Function Requires IL-2 Receptor Signaling but Not CD28, CD40, IL-12Rβ2, or T-bet ¹

Cortny A. Williams; Susan E. Murray; Andrew D. Weinberg; David C. Parker

J Immunol (2007) 178 (12): 7694–7702.

View articletitled, OX40-Mediated Differentiation to Effector Function Requires IL-2 Receptor Signaling but Not CD28, CD40, IL-12Rβ2, or T-bet<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tumor-Reactive CD4⁺ T Cell Responses to the Melanoma-Associated Chondroitin Sulphate Proteoglycan in Melanoma Patients and Healthy Individuals in the Absence of Autoimmunity ¹

Cornelia Erfurt; Zhaojun Sun; Ina Haendle; Beatrice Schuler-Thurner; Carlo Heirman; Kris Thielemans; Pierre van der Bruggen; Gerold Schuler; Erwin S. Schultz

J Immunol (2007) 178 (12): 7703–7709.

View articletitled, Tumor-Reactive CD4<sup>+</sup> T Cell Responses to the Melanoma-Associated Chondroitin Sulphate Proteoglycan in Melanoma Patients and Healthy Individuals in the Absence of Autoimmunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Loss of Telomerase Activity in Highly Differentiated CD8⁺CD28⁻CD27⁻ T Cells Is Associated with Decreased Akt (Ser⁴⁷³) Phosphorylation ¹

Fiona J. Plunkett; Ornella Franzese; Helene M. Finney; Jean M. Fletcher; Lavina L. Belaramani; Mike Salmon; Inderjeet Dokal; David Webster; Alastair D. G. Lawson; Arne N. Akbar

J Immunol (2007) 178 (12): 7710–7719.

View articletitled, The Loss of Telomerase Activity in Highly Differentiated CD8<sup>+</sup>CD28<sup>−</sup>CD27<sup>−</sup> T Cells Is Associated with Decreased Akt (Ser<sup>473</sup>) Phosphorylation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD4⁺ T Cells from Simian Immunodeficiency Virus Disease-Resistant Sooty Mangabeys Produce More IL-2 Than Cells from Disease-Susceptible Species: Involvement of p300 and CREB at the Proximal IL-2 Promoter in IL-2 Up-Regulation ¹

Pavel Bostik; Erika S. Noble; Susan T. Stephenson; Francois Villinger; Aftab A. Ansari

J Immunol (2007) 178 (12): 7720–7729.

View articletitled, CD4<sup>+</sup> T Cells from Simian Immunodeficiency Virus Disease-Resistant Sooty Mangabeys Produce More IL-2 Than Cells from Disease-Susceptible Species: Involvement of p300 and CREB at the Proximal IL-2 Promoter in IL-2 Up-Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Phenotypic and Functional Effects of Heat Shock Protein 90 Inhibition on Dendritic Cell

Jooeun Bae; Constantine Mitsiades; Yu-Tzu Tai; Robert Bertheau; Masood Shammas; Ramesh Babu Batchu; Cheng Li; Lawrence Catley; Rao Prabhala; Kenneth C. Anderson; Nikhil C. Munshi

J Immunol (2007) 178 (12): 7730–7737.

View articletitled, Phenotypic and Functional Effects of Heat Shock Protein 90 Inhibition on Dendritic Cell

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Transcriptional Targeting of B Cells for Induction of Peripheral CD8 T Cell Tolerance ¹

Melanie Werner-Klein; Christiane Dresch; Peggy Marconi; Thomas Brocker

J Immunol (2007) 178 (12): 7738–7746.

View articletitled, Transcriptional Targeting of B Cells for Induction of Peripheral CD8 T Cell Tolerance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Requirements for T Lymphocyte Migration in Explanted Lymph Nodes ¹

Julie H. Huang; L. Isabel Cárdenas-Navia; Charles C. Caldwell; Troy J. Plumb; Caius G. Radu; Paulo N. Rocha; Tuere Wilder; Jonathan S. Bromberg; Bruce N. Cronstein; Michail Sitkovsky; Mark W. Dewhirst; Michael L. Dustin

J Immunol (2007) 178 (12): 7747–7755.

View articletitled, Requirements for T Lymphocyte Migration in Explanted Lymph Nodes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Availability of a Diversely Avid CD8⁺ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24_19–27 Epitope ¹

J Immunol (2007) 178 (12): 7756–7766.

View articletitled, Availability of a Diversely Avid CD8<sup>+</sup> T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24<sub>19–27</sub> Epitope<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Negative Regulation of TCR Signaling by NF-κB2/p100 ¹

Diana Legarda-Addison; Adrian T. Ting

J Immunol (2007) 178 (12): 7767–7778.

View articletitled, Negative Regulation of TCR Signaling by NF-κB2/p100<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR Agonists Selectively Promote Terminal Plasma Cell Differentiation of B Cell Subsets Specialized in Thymus-Independent Responses ¹

Laurent Genestier; Morgan Taillardet; Paul Mondiere; Hanane Gheit; Chantal Bella; Thierry Defrance

J Immunol (2007) 178 (12): 7779–7786.

View articletitled, TLR Agonists Selectively Promote Terminal Plasma Cell Differentiation of B Cell Subsets Specialized in Thymus-Independent Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Small Rho GTPases Mediate Tumor-Induced Inhibition of Endocytic Activity of Dendritic Cells ¹

Irina L. Tourkova; Galina V. Shurin; Sheng Wei; Michael R. Shurin

J Immunol (2007) 178 (12): 7787–7793.

View articletitled, Small Rho GTPases Mediate Tumor-Induced Inhibition of Endocytic Activity of Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Exposure of Myeloid Dendritic Cells to Exogenous or Endogenous IL-10 during Maturation Determines Their Longevity ¹

W. L. William Chang; Nicole Baumgarth; Meghan K. Eberhardt; C. Y. Daniel Lee; Colin A. Baron; Jeff P. Gregg; Peter A. Barry

J Immunol (2007) 178 (12): 7794–7804.

View articletitled, Exposure of Myeloid Dendritic Cells to Exogenous or Endogenous IL-10 during Maturation Determines Their Longevity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunomodulatory Effects of Viral TLR Ligands on Experimental Asthma Depend on the Additive Effects of IL-12 and IL-10 ¹

Serdar Sel; Michael Wegmann; Sarper Sel; Stefan Bauer; Holger Garn; Gottfried Alber; Harald Renz

J Immunol (2007) 178 (12): 7805–7813.

View articletitled, Immunomodulatory Effects of Viral TLR Ligands on Experimental Asthma Depend on the Additive Effects of IL-12 and IL-10<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Protein Kinase Cδ Regulates Antigen Receptor-Induced Lytic Granule Polarization in Mouse CD8⁺ CTL ¹

Jennifer S. Y. Ma; Ngozi Monu; David T. Shen; Ingrid Mecklenbräuker; Nadežda Radoja; Tarik F. Haydar; Michael Leitges; Alan B. Frey; Stanislav Vukmanović; Saša Radoja

J Immunol (2007) 178 (12): 7814–7821.

View articletitled, Protein Kinase Cδ Regulates Antigen Receptor-Induced Lytic Granule Polarization in Mouse CD8<sup>+</sup> CTL<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Expression of the Voltage-Gated Sodium Channel NaV1.5 in the Macrophage Late Endosome Regulates Endosomal Acidification ¹

Michael D. Carrithers; Sulayman Dib-Hajj; Lisette M. Carrithers; Gouzel Tokmoulina; Marc Pypaert; Elizabeth A. Jonas; Stephen G. Waxman

J Immunol (2007) 178 (12): 7822–7832.

View articletitled, Expression of the Voltage-Gated Sodium Channel NaV1.5 in the Macrophage Late Endosome Regulates Endosomal Acidification<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification and Characterization of Novel Bone Marrow Myeloid DEC205⁺Gr-1⁺ Cell Subsets That Differentially Express Chemokine and TLRs

Roberta J. Lamb; Renold J. Capocasale; Karen E. Duffy; Robert T. Sarisky; M. Lamine Mbow

J Immunol (2007) 178 (12): 7833–7839.

View articletitled, Identification and Characterization of Novel Bone Marrow Myeloid DEC205<sup>+</sup>Gr-1<sup>+</sup> Cell Subsets That Differentially Express Chemokine and TLRs

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IgG Opsonization of HIV Impedes Provirus Formation in and Infection of Dendritic Cells and Subsequent Long-Term Transfer to T Cells ¹

Doris Wilflingseder; Zoltan Banki; Eduardo Garcia; Monika Pruenster; Gerald Pfister; Brigitte Muellauer; Damjan S. Nikolic; Christoph Gassner; Christoph G. Ammann; Manfred P. Dierich; Vincent Piguet; Heribert Stoiber

J Immunol (2007) 178 (12): 7840–7848.

View articletitled, IgG Opsonization of HIV Impedes Provirus Formation in and Infection of Dendritic Cells and Subsequent Long-Term Transfer to T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Low-Dose Peptide Tolerance Therapy of Lupus Generates Plasmacytoid Dendritic Cells That Cause Expansion of Autoantigen-Specific Regulatory T Cells and Contraction of Inflammatory Th17 Cells ¹^²

Hee-Kap Kang; Michael Liu; Syamal K. Datta

J Immunol (2007) 178 (12): 7849–7858.

View articletitled, Low-Dose Peptide Tolerance Therapy of Lupus Generates Plasmacytoid Dendritic Cells That Cause Expansion of Autoantigen-Specific Regulatory T Cells and Contraction of Inflammatory Th17 Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses ¹

Monther Al-Alwan; Qiujiang Du; Sen Hou; Baher Nashed; Yijun Fan; Xi Yang; Aaron J. Marshall

J Immunol (2007) 178 (12): 7859–7867.

View articletitled, Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis ¹

Jamie G. Evans; Karina A. Chavez-Rueda; Ayad Eddaoudi; Almut Meyer-Bahlburg; David J. Rawlings; Michael R. Ehrenstein; Claudia Mauri

J Immunol (2007) 178 (12): 7868–7878.

View articletitled, Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Coexpression of IL-5 and Eotaxin-2 in Mice Creates an Eosinophil-Dependent Model of Respiratory Inflammation with Characteristics of Severe Asthma ¹

Sergei I. Ochkur; Elizabeth A. Jacobsen; Cheryl A. Protheroe; Travis L. Biechele; Ralph S. Pero; Michael P. McGarry; Huiying Wang; Katie R. O’Neill; Dana C. Colbert; Thomas V. Colby; Huahao Shen; Michael R. Blackburn; Charles C. Irvin; James J. Lee; Nancy A. Lee

J Immunol (2007) 178 (12): 7879–7889.

View articletitled, Coexpression of IL-5 and Eotaxin-2 in Mice Creates an Eosinophil-Dependent Model of Respiratory Inflammation with Characteristics of Severe Asthma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Quantitative Analysis of the Variables Affecting the Repertoire of T Cell Specificities Recognized after Vaccinia Virus Infection ¹

Erika Assarsson; John Sidney; Carla Oseroff; Valerie Pasquetto; Huynh-Hoa Bui; Nicole Frahm; Christian Brander; Bjoern Peters; Howard Grey; Alessandro Sette

J Immunol (2007) 178 (12): 7890–7901.

View articletitled, A Quantitative Analysis of the Variables Affecting the Repertoire of T Cell Specificities Recognized after Vaccinia Virus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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C5a-Blockade Improves Burn-Induced Cardiac Dysfunction ¹

Laszlo M. Hoesel; Andreas D. Niederbichler; Julia Schaefer; Kyros R. Ipaktchi; Hongwei Gao; Daniel Rittirsch; Matthew J. Pianko; Peter M. Vogt; J. Vidya Sarma; Grace L. Su; Saman Arbabi; Margaret V. Westfall; Stewart C. Wang; Mark R. Hemmila; Peter A. Ward

J Immunol (2007) 178 (12): 7902–7910.

View articletitled, C5a-Blockade Improves Burn-Induced Cardiac Dysfunction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

RNA Interference Elucidates the Role of Focal Adhesion Kinase in HLA Class I-Mediated Focal Adhesion Complex Formation and Proliferation in Human Endothelial Cells ¹

Yi-Ping Jin; Yael Korin; Xiaohai Zhang; Peter T. Jindra; Enrique Rozengurt; Elaine F. Reed

J Immunol (2007) 178 (12): 7911–7922.

View articletitled, RNA Interference Elucidates the Role of Focal Adhesion Kinase in HLA Class I-Mediated Focal Adhesion Complex Formation and Proliferation in Human Endothelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Paratope Plasticity in Diverse Modes Facilitates Molecular Mimicry in Antibody Response ¹

Lavanya Krishnan; Suvendu Lomash; Beena Patricia Jeevan Raj; Kanwal J. Kaur; Dinakar M. Salunke

J Immunol (2007) 178 (12): 7923–7931.

View articletitled, Paratope Plasticity in Diverse Modes Facilitates Molecular Mimicry in Antibody Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Transporter Associated with Antigen-Processing Independent Vacuolar Pathway for the MHC Class I-Mediated Presentation of Endogenous Transmembrane Proteins

Neeraj Tiwari; Natalio Garbi; Thomas Reinheckel; Gerhard Moldenhauer; Günter J. Hämmerling; Frank Momburg

J Immunol (2007) 178 (12): 7932–7942.

View articletitled, A Transporter Associated with Antigen-Processing Independent Vacuolar Pathway for the MHC Class I-Mediated Presentation of Endogenous Transmembrane Proteins

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IMMUNOGENETICS

Episodes of Natural Selection Shaped the Interactions of IgA-Fc with FcαRI and Bacterial Decoy Proteins ¹

Laurent Abi-Rached; Kristel Dorighi; Paul J. Norman; Makoto Yawata; Peter Parham

J Immunol (2007) 178 (12): 7943–7954.

View articletitled, Episodes of Natural Selection Shaped the Interactions of IgA-Fc with FcαRI and Bacterial Decoy Proteins<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Early Diversification of the TNF Superfamily in Teleosts: Genomic Characterization and Expression Analysis ¹

Gavin W. Glenney; Gregory D. Wiens

J Immunol (2007) 178 (12): 7955–7973.

View articletitled, Early Diversification of the TNF Superfamily in Teleosts: Genomic Characterization and Expression Analysis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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HOST DEFENSE

IL-10 Regulates Movement of Intestinally Derived CD4⁺ T Cells to the Liver ¹

Susan K. Bliss; Stuart P. Bliss; Daniel P. Beiting; Ana Alcaraz; Judith A. Appleton

J Immunol (2007) 178 (12): 7974–7983.

View articletitled, IL-10 Regulates Movement of Intestinally Derived CD4<sup>+</sup> T Cells to the Liver<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cells Derived from Murine Colonic Mucosa Have Unique Functional and Phenotypic Characteristics ¹

Shunsuke Takenaka; Ekaterina Safroneeva; Zhou Xing; Jack Gauldie

J Immunol (2007) 178 (12): 7984–7993.

View articletitled, Dendritic Cells Derived from Murine Colonic Mucosa Have Unique Functional and Phenotypic Characteristics<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lung Dendritic Cells Rapidly Mediate Anthrax Spore Entry through the Pulmonary Route ¹

Aurélie Cleret; Anne Quesnel-Hellmann; Alexandra Vallon-Eberhard; Bernard Verrier; Steffen Jung; Dominique Vidal; Jacques Mathieu; Jean-Nicolas Tournier

J Immunol (2007) 178 (12): 7994–8001.

View articletitled, Lung Dendritic Cells Rapidly Mediate Anthrax Spore Entry through the Pulmonary Route<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Depletion of CD8⁺ Cells in Sooty Mangabey Monkeys Naturally Infected with Simian Immunodeficiency Virus Reveals Limited Role for Immune Control of Virus Replication in a Natural Host Species ¹

Ashley P. Barry; Guido Silvestri; Jeffrey T. Safrit; Beth Sumpter; Natalia Kozyr; Harold M. McClure; Silvija I. Staprans; Mark B. Feinberg

J Immunol (2007) 178 (12): 8002–8012.

View articletitled, Depletion of CD8<sup>+</sup> Cells in Sooty Mangabey Monkeys Naturally Infected with Simian Immunodeficiency Virus Reveals Limited Role for Immune Control of Virus Replication in a Natural Host Species<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Macrophage-Inflammatory Protein-3α Mediates Epidermal Growth Factor Receptor Transactivation and ERK1/2 MAPK Signaling in Caco-2 Colonic Epithelial Cells via Metalloproteinase-Dependent Release of Amphiregulin ¹

Sarah Keates; Xinbing Han; Ciarán P. Kelly; Andrew C. Keates

J Immunol (2007) 178 (12): 8013–8021.

View articletitled, Macrophage-Inflammatory Protein-3α Mediates Epidermal Growth Factor Receptor Transactivation and ERK1/2 MAPK Signaling in Caco-2 Colonic Epithelial Cells via Metalloproteinase-Dependent Release of Amphiregulin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Nod-Like Receptor Family Member Naip5/Birc1e Restricts Legionella pneumophila Growth Independently of Caspase-1 Activation ¹

Mohamed Lamkanfi; Amal Amer; Thirumala-Devi Kanneganti; Raúl Muñoz-Planillo; Grace Chen; Peter Vandenabeele; Anne Fortier; Philippe Gros; Gabriel Núñez

J Immunol (2007) 178 (12): 8022–8027.

View articletitled, The Nod-Like Receptor Family Member Naip5/Birc1e Restricts <em>Legionella pneumophila</em> Growth Independently of Caspase-1 Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-10 Underlies Distinct Susceptibility of BALB/c and C57BL/6 Mice to Mycobacterium avium Infection and Influences Efficacy of Antibiotic Therapy ¹

Susana Roque; Claudia Nobrega; Rui Appelberg; Margarida Correia-Neves

J Immunol (2007) 178 (12): 8028–8035.

View articletitled, IL-10 Underlies Distinct Susceptibility of BALB/c and C57BL/6 Mice to <em>Mycobacterium avium</em> Infection and Influences Efficacy of Antibiotic Therapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Leukotriene B₄ Triggers the In Vitro and In Vivo Release of Potent Antimicrobial Agents ¹

Louis Flamand; Michel J. Tremblay; Pierre Borgeat

J Immunol (2007) 178 (12): 8036–8045.

View articletitled, Leukotriene B<sub>4</sub> Triggers the In Vitro and In Vivo Release of Potent Antimicrobial Agents<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Human Neutrophil Defensins Increase Neutrophil Uptake of Influenza A Virus and Bacteria and Modify Virus-Induced Respiratory Burst Responses

Tesfaldet Tecle; Mitchell R. White; Don Gantz; Erika C. Crouch; Kevan L. Hartshorn

J Immunol (2007) 178 (12): 8046–8052.

View articletitled, Human Neutrophil Defensins Increase Neutrophil Uptake of Influenza A Virus and Bacteria and Modify Virus-Induced Respiratory Burst Responses

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INFLAMMATION

Expression and Regulation of the Metalloproteinase ADAM-8 during Human Neutrophil Pathophysiological Activation and Its Catalytic Activity on L-Selectin Shedding ¹

Maria Gómez-Gaviro; Maria Domínguez-Luis; Javier Canchado; Jero Calafat; Hans Janssen; Enrique Lara-Pezzi; Anne Fourie; Antonio Tugores; Agustín Valenzuela-Fernández; Faustino Mollinedo; Francisco Sánchez-Madrid; Federico Díaz-González

J Immunol (2007) 178 (12): 8053–8063.

View articletitled, Expression and Regulation of the Metalloproteinase ADAM-8 during Human Neutrophil Pathophysiological Activation and Its Catalytic Activity on L-Selectin Shedding<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulated Shedding of Transmembrane Chemokines by the Disintegrin and Metalloproteinase 10 Facilitates Detachment of Adherent Leukocytes ¹

Christian Hundhausen; Alexander Schulte; Beate Schulz; Michael G. Andrzejewski; Nicole Schwarz; Philipp von Hundelshausen; Ulrike Winter; Krzysztof Paliga; Karina Reiss; Paul Saftig; Christian Weber; Andreas Ludwig

J Immunol (2007) 178 (12): 8064–8072.

View articletitled, Regulated Shedding of Transmembrane Chemokines by the Disintegrin and Metalloproteinase 10 Facilitates Detachment of Adherent Leukocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Long-Term Commitment to Inflammation-Seeking Homing in CD4⁺ Effector Cells ¹

Silke Jennrich; Boris A. Ratsch; Alf Hamann; Uta Syrbe

J Immunol (2007) 178 (12): 8073–8080.

View articletitled, Long-Term Commitment to Inflammation-Seeking Homing in CD4<sup>+</sup> Effector Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Histamine 4 Receptor Activation Induces Recruitment of FoxP3⁺ T Cells and Inhibits Allergic Asthma in a Murine Model ¹

Ross K. Morgan; Brian McAllister; Lillian Cross; Daniel S. Green; Hardy Kornfeld; David M. Center; William W. Cruikshank

J Immunol (2007) 178 (12): 8081–8089.

View articletitled, Histamine 4 Receptor Activation Induces Recruitment of FoxP3<sup>+</sup> T Cells and Inhibits Allergic Asthma in a Murine Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD8⁺ T Cells Are Required for Inflammation and Destruction in Cigarette Smoke-Induced Emphysema in Mice ¹

Toshitaka Maeno; A. McGarry Houghton; Pablo A. Quintero; Sandra Grumelli; Caroline A. Owen; Steven D. Shapiro

J Immunol (2007) 178 (12): 8090–8096.

View articletitled, CD8<sup>+</sup> T Cells Are Required for Inflammation and Destruction in Cigarette Smoke-Induced Emphysema in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Monocyte Chemoattractant Protein-1 Production by Intestinal Myofibroblasts in Response to Staphylococcal Enterotoxin A: Relevance to Staphylococcal Enterotoxigenic Disease ¹

Irina V. Pinchuk; Ellen J. Beswick; Jamal I. Saada; Giovanni Suarez; John Winston; Randy C. Mifflin; John F. Di Mari; Don W. Powell; Victor E. Reyes

J Immunol (2007) 178 (12): 8097–8106.

View articletitled, Monocyte Chemoattractant Protein-1 Production by Intestinal Myofibroblasts in Response to Staphylococcal Enterotoxin A: Relevance to Staphylococcal Enterotoxigenic Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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STAT1 Activation Causes Translocation of Bax to the Endoplasmic Reticulum during the Resolution of Airway Mucous Cell Hyperplasia by IFN-γ ¹

Barbara A. Stout; Karla Melendez; JeanClare Seagrave; Michael J. Holtzman; Bridget Wilson; Jialing Xiang; Yohannes Tesfaigzi

J Immunol (2007) 178 (12): 8107–8116.

View articletitled, STAT1 Activation Causes Translocation of Bax to the Endoplasmic Reticulum during the Resolution of Airway Mucous Cell Hyperplasia by IFN-γ<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TNF-α Inhibits Macrophage Clearance of Apoptotic Cells via Cytosolic Phospholipase A₂ and Oxidant-Dependent Mechanisms ¹

Kathleen McPhillips; William J. Janssen; Moumita Ghosh; Aideen Byrne; Shyra Gardai; Linda Remigio; Donna L. Bratton; Jihee L. Kang; Peter Henson

J Immunol (2007) 178 (12): 8117–8126.

View articletitled, TNF-α Inhibits Macrophage Clearance of Apoptotic Cells via Cytosolic Phospholipase A<sub>2</sub> and Oxidant-Dependent Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification of Ectonucleotidases CD39 and CD73 in Innate Protection during Acute Lung Injury ¹

Tobias Eckle; Lars Füllbier; Manfred Wehrmann; Joseph Khoury; Michel Mittelbronn; Juan Ibla; Peter Rosenberger; Holger K. Eltzschig

J Immunol (2007) 178 (12): 8127–8137.

View articletitled, Identification of Ectonucleotidases CD39 and CD73 in Innate Protection during Acute Lung Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Proinflammatory Effect of Prostaglandin E₂ in Experimental Inflammatory Bowel Disease Is Mediated through the IL-23→IL-17 Axis ¹

Amir F. Sheibanie; Jui-Hung Yen; Tanzilya Khayrullina; Frances Emig; Ming Zhang; Ronald Tuma; Doina Ganea

J Immunol (2007) 178 (12): 8138–8147.

View articletitled, The Proinflammatory Effect of Prostaglandin E<sub>2</sub> in Experimental Inflammatory Bowel Disease Is Mediated through the IL-23→IL-17 Axis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Pulmonary Stromal-Derived Factor-1 Expression and Effect on Neutrophil Recruitment during Acute Lung Injury ¹

Joseph M. Petty; Viranuj Sueblinvong; Christopher C. Lenox; Christine C. Jones; Gregory P. Cosgrove; Carlyne D. Cool; Pradeep R. Rai; Kevin K. Brown; Daniel J. Weiss; Matthew E. Poynter; Benjamin T. Suratt

J Immunol (2007) 178 (12): 8148–8157.

View articletitled, Pulmonary Stromal-Derived Factor-1 Expression and Effect on Neutrophil Recruitment during Acute Lung Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Fibronectin- and Vitronectin-Induced Microglial Activation and Matrix Metalloproteinase-9 Expression Is Mediated by Integrins α₅β₁ and α_vβ₅ ¹

Richard Milner; Stephen J. Crocker; Stephanie Hung; Xiaoyun Wang; Ricardo F. Frausto; Gregory J. del Zoppo

J Immunol (2007) 178 (12): 8158–8167.

View articletitled, Fibronectin- and Vitronectin-Induced Microglial Activation and Matrix Metalloproteinase-9 Expression Is Mediated by Integrins α<sub>5</sub>β<sub>1</sub> and α<sub>v</sub>β<sub>5</sub><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Shiga Toxin Produced by Enterohemorrhagic Escherichia coli Inhibits PI3K/NF-κB Signaling Pathway in Globotriaosylceramide-3-Negative Human Intestinal Epithelial Cells ¹

Alain P. Gobert; Marjolaine Vareille; Anne-Lise Glasser; Thomas Hindré; Thibaut de Sablet; Christine Martin

J Immunol (2007) 178 (12): 8168–8174.

View articletitled, Shiga Toxin Produced by Enterohemorrhagic <em>Escherichia coli</em> Inhibits PI3K/NF-κB Signaling Pathway in Globotriaosylceramide-3-Negative Human Intestinal Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System ¹

Jason M. Millward; Maria Caruso; Iain L. Campbell; Jack Gauldie; Trevor Owens

J Immunol (2007) 178 (12): 8175–8182.

View articletitled, IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications ¹

Laura C. Bover; Marina Cardó-Vila; Akihiko Kuniyasu; Jessica Sun; Roberto Rangel; Motohiro Takeya; Bharat B. Aggarwal; Wadih Arap; Renata Pasqualini

J Immunol (2007) 178 (12): 8183–8194.

View articletitled, A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Characterization of Reciprocal Lmb1–4 Interval MRL-Fas^lpr and C57BL/6-Fas^lpr Congenic Mice Reveals Significant Effects from Lmb3¹

Marie-Laure Santiago-Raber; M. Katarina Haraldsson; Argyrios N. Theofilopoulos; Dwight H. Kono

J Immunol (2007) 178 (12): 8195–8202.

View articletitled, Characterization of Reciprocal <em>Lmb1–4</em> Interval MRL-<em>Fas</em><sup><em>lpr</em></sup> and C57BL/6-<em>Fas</em><sup><em>lpr</em></sup> Congenic Mice Reveals Significant Effects from <em>Lmb3</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of DMBT1 via NOD2 and TLR4 in Intestinal Epithelial Cells Modulates Bacterial Recognition and Invasion ¹

Philip Rosenstiel; Christian Sina; Caroline End; Marcus Renner; Stefan Lyer; Andreas Till; Stephan Hellmig; Susanna Nikolaus; Ulrich R. Fölsch; Burkhard Helmke; Frank Autschbach; Peter Schirmacher; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer; Stefan Schreiber

J Immunol (2007) 178 (12): 8203–8211.

View articletitled, Regulation of <em>DMBT1</em> via NOD2 and TLR4 in Intestinal Epithelial Cells Modulates Bacterial Recognition and Invasion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Loss of Discrete Memory B Cell Subsets Is Associated with Impaired Immunization Responses in HIV-1 Infection and May Be a Risk Factor for Invasive Pneumococcal Disease ¹

Melanie Hart; Alan Steel; Sally A. Clark; Graeme Moyle; Mark Nelson; Don C. Henderson; Robert Wilson; Frances Gotch; Brian Gazzard; Peter Kelleher

J Immunol (2007) 178 (12): 8212–8220.

View articletitled, Loss of Discrete Memory B Cell Subsets Is Associated with Impaired Immunization Responses in HIV-1 Infection and May Be a Risk Factor for Invasive Pneumococcal Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8⁺ T cells with regime-dependent cytokine/granzyme B profiles.

C. Ranasinghe; S. J. Turner; C. McArthur; D. B. Sutherland; J.-H. Kim; P. C. Doherty; I. A. Ramshaw

J Immunol (2007) 178 (12): 8221.

View articletitled, Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8<sup>+</sup> T cells with regime-dependent cytokine/granzyme B profiles.

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Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.

M. Fuxa; M. Busslinger

J Immunol (2007) 178 (12): 8221.

View articletitled, Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of <em>Pax5</em> in support of its B cell identity function.

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Cover Image

Cover Image

On the cover: Th17 cells infiltrate the kidneys of mice with lupus nephritis. Immunohistochemistry shows perivascular, interstitial, and glomerular infiltration of Th17 cells in control lupus mice. This inflammatory cell infiltration is prevented by low-dose tolerance therapy with nucleosomal histone peptide H4 (71-94). Kang, H.-K., M. Liu, and S. K. Datta. 2007. Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells. J. Immunol. 178: 7849–7858.
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