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Issues
1 February 2007
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
A Golden Anniversary: Recognition That Rheumatoid Arthritis Sera Contain Autoantibodies Specific for Determinants on Native IgG Molecules
J Immunol (2007) 178 (3): 1227–1228.
BRIEF REVIEWS
TLR4, Ethanol, and Lipid Rafts: A New Mechanism of Ethanol Action with Implications for other Receptor-Mediated Effects
J Immunol (2007) 178 (3): 1243–1249.
CUTTING EDGE
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Activating Ly-49 Receptors Regulate LFA-1-Mediated Adhesion by NK Cells1
J Immunol (2007) 178 (3): 1261–1267.
Tolerization of Tumor-Specific T Cells Despite Efficient Initial Priming in a Primary Murine Model of Prostate Cancer1
J Immunol (2007) 178 (3): 1268–1276.
An In Vivo Cytotoxicity Threshold for Influenza A Virus-Specific Effector and Memory CD8+ T Cells1
J Immunol (2007) 178 (3): 1285–1292.
An Alternative Pathway of NF-κB Activation Results in Maturation and T Cell Priming Activity of Dendritic Cells Overexpressing a Mutated IκBα1
Fabrice Moore; Sofia Buonocore; Ezra Aksoy; Najate Ouled-Haddou; Stanislas Goriely; Elena Lazarova; Frédéric Paulart; Carlo Heirman; Elsy Vaeremans; Kris Thielemans; Michel Goldman; Véronique Flamand
J Immunol (2007) 178 (3): 1301–1311.
The Neutrophil-Activating Protein of Helicobacter pylori Crosses Endothelia to Promote Neutrophil Adhesion In Vivo1
Alessandra Polenghi; Fleur Bossi; Fabio Fischetti; Paolo Durigutto; Anna Cabrelle; Nicola Tamassia; Marco A. Cassatella; Cesare Montecucco; Francesco Tedesco; Marina de Bernard
J Immunol (2007) 178 (3): 1312–1320.
Environmental and Intrinsic Factors Lead to Antigen Unresponsiveness in CD4+ Recent Thymic Emigrants from Aged Mice1
J Immunol (2007) 178 (3): 1321–1331.
Prevention of Type 1 Diabetes by Invariant NKT Cells Is Independent of Peripheral CD1d Expression1
J Immunol (2007) 178 (3): 1332–1340.
T-bet Regulates the Fate of Th1 and Th17 Lymphocytes in Autoimmunity1
Anne R. Gocke; Petra D. Cravens; Li-Hong Ben; Rehana Z. Hussain; Sara C. Northrop; Michael K. Racke; Amy E. Lovett-Racke
J Immunol (2007) 178 (3): 1341–1348.
IL-12 Rapidly Alters the Functional Profile of Tumor-Associated and Tumor-Infiltrating Macrophages In Vitro and In Vivo1
J Immunol (2007) 178 (3): 1357–1362.
Mitogenic CD28 Signals Require the Exchange Factor Vav1 to Enhance TCR Signaling at the SLP-76-Vav-Itk Signalosome1
J Immunol (2007) 178 (3): 1363–1371.
Streptococcus agalactiae GAPDH Is a Virulence-Associated Immunomodulatory Protein1
Pedro Madureira; Marina Baptista; Marta Vieira; Vanessa Magalhães; Ana Camelo; Liliana Oliveira; Adília Ribeiro; Delfina Tavares; Patrick Trieu-Cuot; Manuel Vilanova; Paula Ferreira
J Immunol (2007) 178 (3): 1379–1387.
Induction of IL-4 Expression in CD4+ T Cells by Thymic Stromal Lymphopoietin1
J Immunol (2007) 178 (3): 1396–1404.
The B Cell Antigen Receptor Controls AP-1 and NFAT Activity through Ras-Mediated Activation of Ral1
J Immunol (2007) 178 (3): 1405–1414.
Improved Outcomes in NOD Mice Treated with a Novel Th2 Cytokine-Biasing NKT Cell Activator1
Claire Forestier; Toshiyuki Takaki; Alberto Molano; Jin S. Im; Ian Baine; Elliot S. Jerud; Petr Illarionov; Rachel Ndonye; Amy R. Howell; Pere Santamaria; Gurdyal S. Besra; Teresa P. DiLorenzo; Steven A. Porcelli
J Immunol (2007) 178 (3): 1415–1425.
B7-DC/PD-L2 Cross-Linking Induces NF-κB-Dependent Protection of Dendritic Cells from Cell Death
J Immunol (2007) 178 (3): 1426–1432.
Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Airway Allergic Responses Depends on IL-10 Induction of TGF-β1
Anthony Joetham; Katsuyuki Takada; Christian Taube; Nobuaki Miyahara; Satoko Matsubara; Toshiyuki Koya; Yeong-Ho Rha; Azzeddine Dakhama; Erwin W. Gelfand
J Immunol (2007) 178 (3): 1433–1442.
F2L, a Peptide Derived from Heme-Binding Protein, Chemoattracts Mouse Neutrophils by Specifically Activating Fpr2, the Low-Affinity N-Formylpeptide Receptor1
Ji-Liang Gao; Aude Guillabert; Jinyue Hu; Yingying Le; Eneko Urizar; Eva Seligman; Kevin J. Fang; Xiaoning Yuan; Virginie Imbault; David Communi; Ji Ming Wang; Marc Parmentier; Philip M. Murphy; Isabelle Migeotte
J Immunol (2007) 178 (3): 1450–1456.
Dendritic Cell-Independent B Cell Activation During Acute Virus Infection: A Role for Early CCR7-Driven B-T Helper Cell Collaboration1
Elke Scandella; Katja Fink; Tobias Junt; Beatrice M. Senn; Evelyn Lattmann; Reinhold Förster; Hans Hengartner; Burkhard Ludewig
J Immunol (2007) 178 (3): 1468–1476.
Expression Patterns of H2-O in Mouse B Cells and Dendritic Cells Correlate with Cell Function1
J Immunol (2007) 178 (3): 1488–1497.
BTNL2, a Butyrophilin/B7-Like Molecule, Is a Negative Costimulatory Molecule Modulated in Intestinal Inflammation
Heather A. Arnett; Sabine S. Escobar; Eva Gonzalez-Suarez; Alison L. Budelsky; Lori A. Steffen; Norman Boiani; Ming Zhang; Gerald Siu; Avery W. Brewer; Joanne L. Viney
J Immunol (2007) 178 (3): 1523–1533.
Plasmacytoid Dendritic Cells Synergize with Myeloid Dendritic Cells in the Induction of Antigen-Specific Antitumor Immune Responses
J Immunol (2007) 178 (3): 1534–1541.
B7-Deficient Autoreactive T Cells Are Highly Susceptible to Suppression by CD4+CD25+ Regulatory T Cells1
Kenneth F. May, Jr.; Xing Chang; Huiming Zhang; Kenneth D. Lute; Penghui Zhou; Ergun Kocak; Pan Zheng; Yang Liu
J Immunol (2007) 178 (3): 1542–1552.
IL-7 Induces Myelopoiesis and Erythropoiesis1
Francesca B. Aiello; Jonathan R. Keller; Kimberly D. Klarmann; Glenn Dranoff; Renata Mazzucchelli; Scott K. Durum
J Immunol (2007) 178 (3): 1553–1563.
Combined TLR/CD40 Stimulation Mediates Potent Cellular Immunity by Regulating Dendritic Cell Expression of CD70 In Vivo1
J Immunol (2007) 178 (3): 1564–1572.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Haplotype-Independent Costimulation of IL-10 Secretion by SDF-1/CXCL12 Proceeds via AP-1 Binding to the Human IL-10 Promoter1
J Immunol (2007) 178 (3): 1581–1588.
Secretory Antibody Formation: Conserved Binding Interactions between J Chain and Polymeric Ig Receptor from Humans and Amphibians1
J Immunol (2007) 178 (3): 1589–1597.
IMMUNOGENETICS
HOST DEFENSE
Synthetic Prostacyclin Analogs Differentially Regulate Macrophage Function via Distinct Analog-Receptor Binding Specificities1
David M. Aronoff; Camila M. Peres; Carlos H. Serezani; Megan N. Ballinger; Jennifer K. Carstens; Nicole Coleman; Bethany B. Moore; R. Stokes Peebles; Lucia H. Faccioli; Marc Peters-Golden
J Immunol (2007) 178 (3): 1628–1634.
Role of CD40-Dependent Down-Regulation of CD154 in Impaired Induction of CD154 in CD4+ T Cells from HIV-1-Infected Patients1
J Immunol (2007) 178 (3): 1645–1653.
Cowpox Virus Evades CTL Recognition and Inhibits the Intracellular Transport of MHC Class I Molecules1
J Immunol (2007) 178 (3): 1654–1661.
Agonistic Anti-CD40 Antibody Profoundly Suppresses the Immune Response to Infection with Lymphocytic Choriomeningitis Virus1
J Immunol (2007) 178 (3): 1662–1670.
Stimulation of Cell Surface CCR5 and CD40 Molecules by Their Ligands or by HSP70 Up-Regulates APOBEC3G Expression in CD4+ T Cells and Dendritic Cells1
Jeffrey Pido-Lopez; Trevor Whittall; Yufei Wang; Lesley A. Bergmeier; Kaboutar Babaahmady; Mahavir Singh; Thomas Lehner
J Immunol (2007) 178 (3): 1671–1679.
Correlates of Preserved CD4+ T Cell Homeostasis during Natural, Nonpathogenic Simian Immunodeficiency Virus Infection of Sooty Mangabeys: Implications for AIDS Pathogenesis
Beth Sumpter; Richard Dunham; Shari Gordon; Jessica Engram; Margaret Hennessy; Audrey Kinter; Mirko Paiardini; Barbara Cervasi; Nichole Klatt; Harold McClure; Jeffrey M. Milush; Silvija Staprans; Donald L. Sodora; Guido Silvestri
J Immunol (2007) 178 (3): 1680–1691.
Differential NKp30 Inducibility in Chimpanzee NK Cells and Conserved NK Cell Phenotype and Function in Long-Term HIV-1-Infected Animals1
Erik Rutjens; Stefania Mazza; Roberto Biassoni; Gerrit Koopman; Luana Radic; Manuela Fogli; Paola Costa; Maria Cristina Mingari; Lorenzo Moretta; Jonathan Heeney; Andrea De Maria
J Immunol (2007) 178 (3): 1702–1712.
The Chemokine Receptor CXCR3 Attenuates the Control of Chronic Mycobacterium tuberculosis Infection in BALB/c Mice1
J Immunol (2007) 178 (3): 1723–1735.
A Novel Role for IκB Kinase (IKK) α and IKKβ in ERK-Dependent Up-Regulation of MUC5AC Mucin Transcription by Streptococcus pneumoniae1
Unhwan Ha; Jae Hyang Lim; Hirofumi Jono; Tomoaki Koga; Amit Srivastava; Richard Malley; Gilles Pagès; Jacques Pouysségur; Jian-Dong Li
J Immunol (2007) 178 (3): 1736–1747.
INFLAMMATION
Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties1
Alexander R. Moschen; Arthur Kaser; Barbara Enrich; Birgit Mosheimer; Milan Theurl; Harald Niederegger; Herbert Tilg
J Immunol (2007) 178 (3): 1748–1758.
Vascular Endothelial Growth Factor Expression in Arthritic Joint Is Regulated by SAF-1 Transcription Factor1
J Immunol (2007) 178 (3): 1774–1782.
CD59, a Complement Regulatory Protein, Controls Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration1
Nalini S. Bora; Sankaranarayanan Kaliappan; Purushottam Jha; Qin Xu; Baalasubramanian Sivasankar; Claire L. Harris; B. Paul Morgan; Puran S. Bora
J Immunol (2007) 178 (3): 1783–1790.
Regulatory T Cell Vaccination without Autoantigen Protects against Experimental Autoimmune Encephalomyelitis1
J Immunol (2007) 178 (3): 1791–1799.
Airway Epithelial NF-κB Activation Modulates Asbestos-Induced Inflammation and Mucin Production In Vivo1
Astrid Haegens; Trisha F. Barrett; Joanna Gell; Arti Shukla; Maximilian MacPherson; Pamela Vacek; Matthew E. Poynter; Kelly J. Butnor; Yvonne M. Janssen-Heininger; Chad Steele; Brooke T. Mossman
J Immunol (2007) 178 (3): 1800–1808.
C3a Is Required for the Production of CXC Chemokines by Tubular Epithelial Cells after Renal Ishemia/Reperfusion1
Joshua M. Thurman; Amanda M. Lenderink; Pamela A. Royer; Kathrin E. Coleman; Jian Zhou; John D. Lambris; Raphael A. Nemenoff; Richard J. Quigg; V. Michael Holers
J Immunol (2007) 178 (3): 1819–1828.
Cathelicidin Antimicrobial Peptides Block Dendritic Cell TLR4 Activation and Allergic Contact Sensitization1
Anna Di Nardo; Marissa H. Braff; Kristen R. Taylor; ChangRim Na; Richard D. Granstein; Jamie E. McInturff; Stephan Krutzik; Robert L. Modlin; Richard L. Gallo
J Immunol (2007) 178 (3): 1829–1834.
Prednisolone Dose-Dependently Influences Inflammation and Coagulation during Human Endotoxemia1
Martijn D. de Kruif; Lucienne C. Lemaire; Ida A. Giebelen; Marieke A. D. van Zoelen; Jennie M. Pater; Petra S. van den Pangaart; Angelique P. Groot; Alex F. de Vos; Peter J. Elliott; Joost C. M. Meijers; Marcel Levi; Tom van der Poll
J Immunol (2007) 178 (3): 1845–1851.
Serum Amyloid A Induces Monocyte Tissue Factor1
Hong Cai; Changjie Song; Ikuko Endoh; Jesse Goyette; Wendy Jessup; S. Ben Freedman; H. Patrick McNeil; Carolyn L. Geczy
J Immunol (2007) 178 (3): 1852–1860.
Osteopontin Induces Ubiquitin-Dependent Degradation of STAT1 in RAW264.7 Murine Macrophages1
J Immunol (2007) 178 (3): 1870–1881.
Diverse and Potent Chemokine Production by Lung CD11bhigh Dendritic Cells in Homeostasis and in Allergic Lung Inflammation1
J Immunol (2007) 178 (3): 1882–1895.
Functions and Regulation of NF-κB RelA during Pneumococcal Pneumonia1
Lee J. Quinton; Matthew R. Jones; Benjamin T. Simms; Mariya S. Kogan; Bryanne E. Robson; Shawn J. Skerrett; Joseph P. Mizgerd
J Immunol (2007) 178 (3): 1896–1903.
Peroxisome Proliferator-Activated Receptor-γ Agonists Suppress the Production of IL-12 Family Cytokines by Activated Glia1
J Immunol (2007) 178 (3): 1904–1913.
CLINICAL IMMUNOLOGY
Unmasking of α-Fetoprotein-Specific CD4+ T Cell Responses in Hepatocellular Carcinoma Patients Undergoing Embolization1
Lakshmana Ayaru; Stephen P. Pereira; Akeel Alisa; Ansar A. Pathan; Roger Williams; Brian Davidson; Andrew K. Burroughs; Tim Meyer; Shahriar Behboudi
J Immunol (2007) 178 (3): 1914–1922.
Effects of Specific Immunotherapy on the B7 Family of Costimulatory Molecules in Allergic Inflammation1
Stefania Piconi; Daria Trabattoni; Marina Saresella; Enrico Iemoli; Monica Schenal; Alessandra Fusi; Manuela Borelli; Lieping Chen; Ambra Mascheri; Mario Clerici
J Immunol (2007) 178 (3): 1931–1937.
Phosphorylated ERM Is Responsible for Increased T Cell Polarization, Adhesion, and Migration in Patients with Systemic Lupus Erythematosus12
Yansong Li; Tatsuhiro Harada; Yuang-Taung Juang; Vasileios C. Kyttaris; Ying Wang; Michael Zidanic; Kenneth Tung; George C. Tsokos
J Immunol (2007) 178 (3): 1938–1947.
IL-18 Is Induced and IL-18 Receptor α Plays a Critical Role in the Pathogenesis of Cigarette Smoke-Induced Pulmonary Emphysema and Inflammation1
Min-Jong Kang; Robert J. Homer; Amy Gallo; Chun Geun Lee; Kristina A. Crothers; Soo Jung Cho; Carolyn Rochester; Hilary Cain; Geoffrey Chupp; Ho Joo Yoon; Jack A. Elias
J Immunol (2007) 178 (3): 1948–1959.
Increased Levels of NF-ATc2 Differentially Regulate CD154 and IL-2 Genes in T Cells from Patients with Systemic Lupus Erythematosus1
J Immunol (2007) 178 (3): 1960–1966.
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Cover Image
Cover Image
On the cover: Laser-induced choroidal neovascularization (CNV) in Cd59a-/- mice. Confocal micrograph of the neovascular complex shows the new vessels as green, whereas the damaged Bruch's membrane and RPE were stained red for elastin. Cd59a-/- mice developed CNV complex early in the disease process. Bora, N. S., S. Kaliappan, P. Jha, Q. Xu, B. Sivasankar, C. L. Harris, B. P. Morgan, and P. S. Bora. 2007. CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration. J. Immunol. 178: 1783–1790.
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