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J Immunol (2007) 178 (5): 2605–2606.

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LETTERS TO THE EDITOR

Comment on “Local CD11c⁺ MHC Class II⁻ Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process”

Christophe von Garnier; Deborah Strickland; Philip Stumbles

J Immunol (2007) 178 (5): 2609.

View articletitled, Comment on “Local CD11c<sup>+</sup> MHC Class II<sup>−</sup> Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process”

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Response to Comment on “Local CD11c⁺ MHC Class II⁻ Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process”

Hongwei Wang; Jürgen Schwarze

J Immunol (2007) 178 (5): 2609–2610.

View articletitled, Response to Comment on “Local CD11c<sup>+</sup> MHC Class II<sup>−</sup> Precursors Generate Lung Dendritic Cells during Respiratory Viral Infection, but Are Depleted in the Process”

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Comment on “Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in Staphylococcus aureus”

Sonja von Aulock; Thomas Hartung; Corinna Hermann

J Immunol (2007) 178 (5): 2610.

View articletitled, Comment on “Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in <em>Staphylococcus aureus</em>”

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Response to Comment on “Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in Staphylococcus aureus”

Masahito Hashimoto; Maiko Furuyashiki; Yasuo Suda

J Immunol (2007) 178 (5): 2610–2611.

View articletitled, Response to Comment on “Not Lipoteichoic Acid but Lipoproteins Appear to Be the Dominant Immunobiologically Active Compounds in <em>Staphylococcus aureus</em>”

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Comment on “Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8⁺ T Cells”

Angelika Schwanninger; Birgit Weinberger; Beatrix Grubeck-Loebenstein

J Immunol (2007) 178 (5): 2611–2612.

View articletitled, Comment on “Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8<sup>+</sup> T Cells”

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Response to Comment on “Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8⁺ T Cells”

Ester M. M. van Leeuwen; René A. W. van Lier; Ineke J. M. ten Berge

J Immunol (2007) 178 (5): 2612.

View articletitled, Response to Comment on “Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8<sup>+</sup> T Cells”

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PILLARS OF IMMUNOLOGY

Human Tumor Immunology at the Molecular Divide

Olivera J. Finn

J Immunol (2007) 178 (5): 2615–2616.

View articletitled, Human Tumor Immunology at the Molecular Divide

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Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science 1991. 254: 1643–1647.

Pierre van der Bruggen; Catia Traversari; Patrick Chomez; Christophe Lurquin; Etienne De Plaen; Benoît J. Van den Eynde; Alexander Knuth; Thierry Boon

J Immunol (2007) 178 (5): 2617–2621.

View articletitled, Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. <em>Science</em> 1991. 254: 1643–1647.

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BRIEF REVIEWS

The JAK-STAT Signaling Pathway: Input and Output Integration ¹

Peter J. Murray

J Immunol (2007) 178 (5): 2623–2629.

View articletitled, The JAK-STAT Signaling Pathway: Input and Output Integration<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: TFII-I Controls B Cell Proliferation via Regulating NF-κB ¹

Todd Ashworth; Ananda L. Roy

J Immunol (2007) 178 (5): 2631–2635.

View articletitled, Cutting Edge: TFII-I Controls B Cell Proliferation via Regulating NF-κB<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Bim Is Required for Superantigen-Mediated B Cell Death ¹

Carl S. Goodyear; Maripat Corr; Fujimi Sugiyama; David L. Boyle; Gregg J. Silverman

J Immunol (2007) 178 (5): 2636–2640.

View articletitled, Cutting Edge: Bim Is Required for Superantigen-Mediated B Cell Death<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations

Andreas Kuglstatter; Armando G. Villaseñor; David Shaw; Simon W. Lee; Stan Tsing; Linghao Niu; Kyung W. Song; Jim W. Barnett; Michelle F. Browner

J Immunol (2007) 178 (5): 2641–2645.

View articletitled, Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations

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Cutting Edge: IFN-γ-Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis¹

Ian Justin Glomski; Jean-Philippe Corre; Michèle Mock; Pierre Louis Goossens

J Immunol (2007) 178 (5): 2646–2650.

View articletitled, Cutting Edge: IFN-γ-Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated <em>Bacillus anthracis</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Oseltamivir Decreases T Cell GM1 Expression and Inhibits Clearance of Respiratory Syncytial Virus: Potential Role of Endogenous Sialidase in Antiviral Immunity ¹

Martin L. Moore; Michael H. Chi; Weisong Zhou; Kasia Goleniewska; Jamye F. O’Neal; James N. Higginbotham; R. Stokes Peebles, Jr.

J Immunol (2007) 178 (5): 2651–2654.

View articletitled, Cutting Edge: Oseltamivir Decreases T Cell GM1 Expression and Inhibits Clearance of Respiratory Syncytial Virus: Potential Role of Endogenous Sialidase in Antiviral Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Differential Inhibition of TLR Signaling Pathways by Cell-Permeable Peptides Representing BB Loops of TLRs ¹

Vladimir Y. Toshchakov; Matthew J. Fenton; Stefanie N. Vogel

J Immunol (2007) 178 (5): 2655–2660.

View articletitled, Cutting Edge: Differential Inhibition of TLR Signaling Pathways by Cell-Permeable Peptides Representing BB Loops of TLRs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

Mischo Kursar; Markus Koch; Hans-Willi Mittrücker; Geraldine Nouailles; Kerstin Bonhagen; Thomas Kamradt; Stefan H. E. Kaufmann

J Immunol (2007) 178 (5): 2661–2665.

View articletitled, Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of <em>Mycobacterium tuberculosis</em>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Murine Neonatal CD4⁺ Cells Are Poised for Rapid Th2 Effector-Like Function ¹

Shawn Rose; Mathias Lichtenheld; Monica R. Foote; Becky Adkins

J Immunol (2007) 178 (5): 2667–2678.

View articletitled, Murine Neonatal CD4<sup>+</sup> Cells Are Poised for Rapid Th2 Effector-Like Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Apoptotic Cells Induce Tolerance by Generating Helpless CD8⁺ T Cells That Produce TRAIL ¹

Thomas S. Griffith; Hirotaka Kazama; Rebecca L. VanOosten; James K. Earle, Jr.; John M. Herndon; Douglas R. Green; Thomas A. Ferguson

J Immunol (2007) 178 (5): 2679–2687.

View articletitled, Apoptotic Cells Induce Tolerance by Generating Helpless CD8<sup>+</sup> T Cells That Produce TRAIL<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection ¹

Monia Draghi; Achal Pashine; Bharati Sanjanwala; Ketevan Gendzekhadze; Claudia Cantoni; David Cosman; Alessandro Moretta; Nicholas M. Valiante; Peter Parham

J Immunol (2007) 178 (5): 2688–2698.

View articletitled, NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunization of Flavivirus West Nile Recombinant Envelope Domain III Protein Induced Specific Immune Response and Protection against West Nile Virus Infection ¹

Jang-Hann J. Chu; Cern-Cher S. Chiang; Mah-Lee Ng

J Immunol (2007) 178 (5): 2699–2705.

View articletitled, Immunization of Flavivirus West Nile Recombinant Envelope Domain III Protein Induced Specific Immune Response and Protection against West Nile Virus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Invariant NKT Cells Amplify the Innate Immune Response to Lipopolysaccharide ¹

Niranjana A. Nagarajan; Mitchell Kronenberg

J Immunol (2007) 178 (5): 2706–2713.

View articletitled, Invariant NKT Cells Amplify the Innate Immune Response to Lipopolysaccharide<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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PD-1:PD-L1 Interactions Contribute to the Functional Suppression of Virus-Specific CD8⁺ T Lymphocytes in the Liver ¹

Holly Maier; Masanori Isogawa; Gordon J. Freeman; Francis V. Chisari

J Immunol (2007) 178 (5): 2714–2720.

View articletitled, PD-1:PD-L1 Interactions Contribute to the Functional Suppression of Virus-Specific CD8<sup>+</sup> T Lymphocytes in the Liver<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cell Function Can Be Modulated through Cooperative Actions of TLR Ligands and Invariant NKT Cells ¹

Ian F. Hermans; Jonathan D. Silk; Uzi Gileadi; S. Hajar Masri; Dawn Shepherd; Kathryn J. Farrand; Mariolina Salio; Vincenzo Cerundolo

J Immunol (2007) 178 (5): 2721–2729.

View articletitled, Dendritic Cell Function Can Be Modulated through Cooperative Actions of TLR Ligands and Invariant NKT Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Epigenetic and Transcriptional Programs Lead to Default IFN-γ Production by γδ T Cells ¹

Liang Chen; Weifeng He; Sean T. Kim; Jian Tao; Yunfei Gao; Hongbo Chi; Andrew M. Intlekofer; Bohdan Harvey; Steven L. Reiner; Zhinan Yin; Richard A. Flavell; Joe Craft

J Immunol (2007) 178 (5): 2730–2736.

View articletitled, Epigenetic and Transcriptional Programs Lead to Default IFN-γ Production by γδ T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Virus-Specific CD8⁺ T Cells in the Liver: Armed and Ready to Kill ¹

Rachael Keating; Wen Yue; John A. Rutigliano; Jenny So; Elvia Olivas; Paul G. Thomas; Peter C. Doherty

J Immunol (2007) 178 (5): 2737–2745.

View articletitled, Virus-Specific CD8<sup>+</sup> T Cells in the Liver: Armed and Ready to Kill<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Gag-Specific CD8⁺ T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression ¹

Jonah B. Sacha; Chungwon Chung; Eva G. Rakasz; Sean P. Spencer; Anna K. Jonas; Alexander T. Bean; Wonhee Lee; Benjamin J. Burwitz; Jason J. Stephany; John T. Loffredo; David B. Allison; Sama Adnan; Akihiko Hoji; Nancy A. Wilson; Thomas C. Friedrich; Jeffrey D. Lifson; Otto O. Yang; David I. Watkins

J Immunol (2007) 178 (5): 2746–2754.

View articletitled, Gag-Specific CD8<sup>+</sup> T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Efficient Activation of Vα14 Invariant NKT Cells by Foreign Lipid Antigen Is Associated with Concurrent Dendritic Cell-Specific Self Recognition ¹

Lu Cheng; Aito Ueno; Suzanne Cho; Jin S. Im; Susanne Golby; Sheng Hou; Steven A. Porcelli; Yang Yang

J Immunol (2007) 178 (5): 2755–2762.

View articletitled, Efficient Activation of Vα14 Invariant NKT Cells by Foreign Lipid Antigen Is Associated with Concurrent Dendritic Cell-Specific Self Recognition<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cells Infiltrating Human Non-Small Cell Lung Cancer Are Blocked at Immature Stage ¹

Ivan Perrot; Dominique Blanchard; Nathalie Freymond; Sylvie Isaac; Benoît Guibert; Yves Pachéco; Serge Lebecque

J Immunol (2007) 178 (5): 2763–2769.

View articletitled, Dendritic Cells Infiltrating Human Non-Small Cell Lung Cancer Are Blocked at Immature Stage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Fetal Immune Responses to Plasmodium falciparum Antigens in a Malaria-Endemic Region of Cameroon ¹

Simon Metenou; Amorsolo L. Suguitan, Jr.; Carole Long; Rose G. F. Leke; Diane Wallace Taylor

J Immunol (2007) 178 (5): 2770–2777.

View articletitled, Fetal Immune Responses to <em>Plasmodium falciparum</em> Antigens in a Malaria-Endemic Region of Cameroon<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD4⁺CD25⁺ T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes ¹

Jovanna González; Esther Tamayo; Inés Santiuste; Regina Marquina; Luis Buelta; Miguel A. González-Gay; Shozo Izui; Marcos López-Hoyos; Jesús Merino; Ramón Merino

J Immunol (2007) 178 (5): 2778–2786.

View articletitled, CD4<sup>+</sup>CD25<sup>+</sup> T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lack of Effective MUC1 Tumor Antigen-Specific Immunity in MUC1-Transgenic Mice Results from a Th/T Regulatory Cell Imbalance That Can Be Corrected by Adoptive Transfer of Wild-Type Th Cells ¹

Michael S. Turner; Patrice A. Cohen; Olivera J. Finn

J Immunol (2007) 178 (5): 2787–2793.

View articletitled, Lack of Effective MUC1 Tumor Antigen-Specific Immunity in MUC1-Transgenic Mice Results from a Th/T Regulatory Cell Imbalance That Can Be Corrected by Adoptive Transfer of Wild-Type Th Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Effect of Both Ultraviolet B Irradiation and Histamine Receptor Function on Allergic Responses to an Inhaled Antigen ¹

Jacqueline P. McGlade; Shelley Gorman; Jason C. Lenzo; Jamie W. Tan; Takeshi Watanabe; John J. Finlay-Jones; Wayne R. Thomas; Prue H. Hart

J Immunol (2007) 178 (5): 2794–2802.

View articletitled, Effect of Both Ultraviolet B Irradiation and Histamine Receptor Function on Allergic Responses to an Inhaled Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Staphylococcus aureus Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 Ligands ¹

Isabelle Bekeredjian-Ding; Seiichi Inamura; Thomas Giese; Hermann Moll; Stefan Endres; Andreas Sing; Ulrich Zähringer; Gunther Hartmann

J Immunol (2007) 178 (5): 2803–2812.

View articletitled, <em>Staphylococcus aureus</em> Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 Ligands<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38^MAPK/MK2 Cascade ¹

Christian Ehlting; Wi S. Lai; Fred Schaper; Erwin D. Brenndörfer; Raphaela-Jessica Matthes; Peter C. Heinrich; Stephan Ludwig; Perry J. Blackshear; Matthias Gaestel; Dieter Häussinger; Johannes G. Bode

J Immunol (2007) 178 (5): 2813–2826.

View articletitled, Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38<sup>MAPK</sup>/MK2 Cascade<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production ¹

Jonathan M. Coquet; Konstantinos Kyparissoudis; Daniel G. Pellicci; Gurdyal Besra; Stuart P. Berzins; Mark J. Smyth; Dale I. Godfrey

J Immunol (2007) 178 (5): 2827–2834.

View articletitled, IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-2/Neuroantigen Fusion Proteins as Antigen-Specific Tolerogens in Experimental Autoimmune Encephalomyelitis (EAE): Correlation of T Cell-Mediated Antigen Presentation and Tolerance Induction ¹

Mark D. Mannie; Barbara A. Clayson; Elizabeth J. Buskirk; Jarret L. DeVine; Jose J. Hernandez; Derek J. Abbott

J Immunol (2007) 178 (5): 2835–2843.

View articletitled, IL-2/Neuroantigen Fusion Proteins as Antigen-Specific Tolerogens in Experimental Autoimmune Encephalomyelitis (EAE): Correlation of T Cell-Mediated Antigen Presentation and Tolerance Induction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD40-CD40 Ligand Interaction between Dendritic Cells and CD8⁺ T Cells Is Needed to Stimulate Maximal T Cell Responses in the Absence of CD4⁺ T Cell Help ¹

Maria Genevive H. Hernandez; Lianjun Shen; Kenneth L. Rock

J Immunol (2007) 178 (5): 2844–2852.

View articletitled, CD40-CD40 Ligand Interaction between Dendritic Cells and CD8<sup>+</sup> T Cells Is Needed to Stimulate Maximal T Cell Responses in the Absence of CD4<sup>+</sup> T Cell Help<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tumor Cells Loaded with α-Galactosylceramide Induce Innate NKT and NK Cell-Dependent Resistance to Tumor Implantation in Mice ¹

Kanako Shimizu; Akira Goto; Mikiko Fukui; Masaru Taniguchi; Shin-ichiro Fujii

J Immunol (2007) 178 (5): 2853–2861.

View articletitled, Tumor Cells Loaded with α-Galactosylceramide Induce Innate NKT and NK Cell-Dependent Resistance to Tumor Implantation in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Involvement of Src and Syk Tyrosine Kinases in HIV-1 Transfer from Dendritic Cells to CD4⁺ T Lymphocytes ¹

Caroline Gilbert; Corinne Barat; Réjean Cantin; Michel J. Tremblay

J Immunol (2007) 178 (5): 2862–2871.

View articletitled, Involvement of Src and Syk Tyrosine Kinases in HIV-1 Transfer from Dendritic Cells to CD4<sup>+</sup> T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells ¹

Rachel Ettinger; Gary P. Sims; Rachel Robbins; David Withers; Randy T. Fischer; Amrie C. Grammer; Stefan Kuchen; Peter E. Lipsky

J Immunol (2007) 178 (5): 2872–2882.

View articletitled, IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tumor Evasion of the Immune System by Converting CD4⁺CD25⁻ T Cells into CD4⁺CD25⁺ T Regulatory Cells: Role of Tumor-Derived TGF-β

Victoria C. Liu; Larry Y. Wong; Thomas Jang; Ali H. Shah; Irwin Park; Ximing Yang; Qiang Zhang; Scott Lonning; Beverly A. Teicher; Chung Lee

J Immunol (2007) 178 (5): 2883–2892.

View articletitled, Tumor Evasion of the Immune System by Converting CD4<sup>+</sup>CD25<sup>−</sup> T Cells into CD4<sup>+</sup>CD25<sup>+</sup> T Regulatory Cells: Role of Tumor-Derived TGF-β

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Induced SHIP Deficiency Expands Myeloid Regulatory Cells and Abrogates Graft-versus-Host Disease ¹

Kim H. T. Paraiso; Tomar Ghansah; Amy Costello; Robert W. Engelman; William G. Kerr

J Immunol (2007) 178 (5): 2893–2900.

View articletitled, Induced SHIP Deficiency Expands Myeloid Regulatory Cells and Abrogates Graft-versus-Host Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Augmentation of Signaling through BCR Containing IgE but not That Containing IgA Due to Lack of CD22-Mediated Signal Regulation ¹

Motohiko Sato; Takahiro Adachi; Takeshi Tsubata

J Immunol (2007) 178 (5): 2901–2907.

View articletitled, Augmentation of Signaling through BCR Containing IgE but not That Containing IgA Due to Lack of CD22-Mediated Signal Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Modulation of CD103 Expression on Human Colon Carcinoma-Specific CTL ¹

Khoon-Lin Ling; Nicolas Dulphy; Pru Bahl; Mariolina Salio; Kevin Maskell; Juan Piris; Bryan F. Warren; Bruce D. George; Neil J. Mortensen; Vincenzo Cerundolo

J Immunol (2007) 178 (5): 2908–2915.

View articletitled, Modulation of CD103 Expression on Human Colon Carcinoma-Specific CTL<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice ¹

Helen Ferry; Paul K. Potter; Tanya L. Crockford; Anastasia Nijnik; Michael R. Ehrenstein; Mark J. Walport; Marina Botto; Richard J. Cornall

J Immunol (2007) 178 (5): 2916–2922.

View articletitled, Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mcl-1 Depletion in Apoptosis Elicited by Ionizing Radiation in Peritoneal Resident Macrophages of C3H Mice

Yoshihisa Kubota; Keiji Kinoshita; Katsutoshi Suetomi; Akira Fujimori; Sentaro Takahashi

J Immunol (2007) 178 (5): 2923–2931.

View articletitled, Mcl-1 Depletion in Apoptosis Elicited by Ionizing Radiation in Peritoneal Resident Macrophages of C3H Mice

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CD4⁺ and CD8⁺ T Cell Survival Is Regulated Differentially by Protein Kinase Cθ, c-Rel, and Protein Kinase B ¹

Samuel D. Saibil; Russell G. Jones; Elissa K. Deenick; Nicole Liadis; Alisha R. Elford; Mitchell G. Vainberg; Heather Baerg; James R. Woodgett; Steve Gerondakis; Pamela S. Ohashi

J Immunol (2007) 178 (5): 2932–2939.

View articletitled, CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Survival Is Regulated Differentially by Protein Kinase Cθ, c-Rel, and Protein Kinase B<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Peroxisome Proliferator-Activated Receptor γ Is Required for Regulatory CD4⁺ T Cell-Mediated Protection against Colitis

Raquel Hontecillas; Josep Bassaganya-Riera

J Immunol (2007) 178 (5): 2940–2949.

View articletitled, Peroxisome Proliferator-Activated Receptor γ Is Required for Regulatory CD4<sup>+</sup> T Cell-Mediated Protection against Colitis

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Fitness of Cell-Mediated Immunity Independent of Repertoire Diversity ¹

Mouhammed AbuAttieh; Michelle Rebrovich; Peter J. Wettstein; Zvezdana Vuk-Pavlovic; Andrew H. Limper; Jeffrey L. Platt; Marilia Cascalho

J Immunol (2007) 178 (5): 2950–2960.

View articletitled, Fitness of Cell-Mediated Immunity Independent of Repertoire Diversity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen ¹

Dipica Haribhai; Wen Lin; Lance M. Relland; Nga Truong; Calvin B. Williams; Talal A. Chatila

J Immunol (2007) 178 (5): 2961–2972.

View articletitled, Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CC Chemokine Receptor 7 Contributes to Gi-Dependent T Cell Motility in the Lymph Node ¹

Takaharu Okada; Jason G. Cyster

J Immunol (2007) 178 (5): 2973–2978.

View articletitled, CC Chemokine Receptor 7 Contributes to Gi-Dependent T Cell Motility in the Lymph Node<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Targeting of Antigen to Dendritic Cells with Poly(γ-Glutamic Acid) Nanoparticles Induces Antigen-Specific Humoral and Cellular Immunity ¹

Tomofumi Uto; Xin Wang; Katsuaki Sato; Misako Haraguchi; Takami Akagi; Mitsuru Akashi; Masanori Baba

J Immunol (2007) 178 (5): 2979–2986.

View articletitled, Targeting of Antigen to Dendritic Cells with Poly(γ-Glutamic Acid) Nanoparticles Induces Antigen-Specific Humoral and Cellular Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Requirement for a Complex of Wiskott-Aldrich Syndrome Protein (WASP) with WASP Interacting Protein in Podosome Formation in Macrophages ¹

Shigeru Tsuboi

J Immunol (2007) 178 (5): 2987–2995.

View articletitled, Requirement for a Complex of Wiskott-Aldrich Syndrome Protein (WASP) with WASP Interacting Protein in Podosome Formation in Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Anti-Nuclear Antibody Production and Autoimmunity in Transgenic Mice That Overexpress the Transcription Factor Bright ¹

Malini Shankar; Jamee C. Nixon; Shannon Maier; Jennifer Workman; A. Darise Farris; Carol F. Webb

J Immunol (2007) 178 (5): 2996–3006.

View articletitled, Anti-Nuclear Antibody Production and Autoimmunity in Transgenic Mice That Overexpress the Transcription Factor Bright<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation ¹

Geoffrey O. Gillard; James Dooley; Matthew Erickson; Leena Peltonen; Andrew G. Farr

J Immunol (2007) 178 (5): 3007–3015.

View articletitled, <em>Aire</em>-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for <em>Aire</em> in Thymic Epithelial Differentiation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Conformational Changes in Mannan-Binding Lectin Bound to Ligand Surfaces ¹

Mingdong Dong; Sailong Xu; Cristiano L. P. Oliveira; Jan S. Pedersen; Steffen Thiel; Flemming Besenbacher; Thomas Vorup-Jensen

J Immunol (2007) 178 (5): 3016–3022.

View articletitled, Conformational Changes in Mannan-Binding Lectin Bound to Ligand Surfaces<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Genomic Organization of the Chicken CD8 Locus Reveals a Novel Family of Immunoreceptor Genes ¹

Hung-Jiun Liaw; Wei-Ru Chen; Yu-Chia Huang; Chung-Wei Tsai; King-Chan Chang; Chia-Lam Kuo

J Immunol (2007) 178 (5): 3023–3030.

View articletitled, Genomic Organization of the Chicken CD8 Locus Reveals a Novel Family of Immunoreceptor Genes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Early Growth Response Transcriptional Regulators Are Dispensable for Macrophage Differentiation ¹

John H. Carter; Warren G. Tourtellotte

J Immunol (2007) 178 (5): 3038–3047.

View articletitled, Early Growth Response Transcriptional Regulators Are Dispensable for Macrophage Differentiation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Transmembrane Mutations to FcγRIIA Alter Its Association with Lipid Rafts: Implications for Receptor Signaling ¹

Erick García-García; Eric J. Brown; Carlos Rosales

J Immunol (2007) 178 (5): 3048–3058.

View articletitled, Transmembrane Mutations to FcγRIIA Alter Its Association with Lipid Rafts: Implications for Receptor Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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17β-Estradiol Induces IL-1α Gene Expression in Rheumatoid Fibroblast-Like Synovial Cells through Estrogen Receptor α (ERα) and Augmentation of Transcriptional Activity of Sp1 by Dissociating Histone Deacetylase 2 from ERα ¹

Yuka Itoh; Hidetoshi Hayashi; Keiji Miyazawa; Soichi Kojima; Tohru Akahoshi; Kikuo Onozaki

J Immunol (2007) 178 (5): 3059–3066.

View articletitled, 17β-Estradiol Induces <em>IL-1</em>α Gene Expression in Rheumatoid Fibroblast-Like Synovial Cells through Estrogen Receptor α (ERα) and Augmentation of Transcriptional Activity of Sp1 by Dissociating Histone Deacetylase 2 from ERα<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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NF-AT-Mediated Expression of TGF-β1 in Tolerant T Cells ¹

Naoko Nakano; Hiroyuki Hosokawa; Masako Kohyama; Nobumichi Hozumi

J Immunol (2007) 178 (5): 3067–3075.

View articletitled, NF-AT-Mediated Expression of TGF-β1 in Tolerant T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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ARTICLES

Reporter Gene Insertions Reveal a Strictly B Lymphoid-Specific Expression Pattern of Pax5 in Support of Its B Cell Identity Function ¹

Martin Fuxa; Meinrad Busslinger

J Immunol (2007) 178 (5): 3031–3037.

View articletitled, Reporter Gene Insertions Reveal a Strictly B Lymphoid-Specific Expression Pattern of <em>Pax5</em> in Support of Its B Cell Identity Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

HLA Transgenic Mice Provide Evidence for a Direct and Dominant Role of HLA Class II Variation in Modulating the Severity of Streptococcal Sepsis ¹

Mohammed M. Nooh; Nagala El-Gengehi; Rita Kansal; Chella S. David; Malak Kotb

J Immunol (2007) 178 (5): 3076–3083.

View articletitled, HLA Transgenic Mice Provide Evidence for a Direct and Dominant Role of HLA Class II Variation in Modulating the Severity of Streptococcal Sepsis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci ¹

Emma Ahlqvist; Robert Bockermann; Rikard Holmdahl

J Immunol (2007) 178 (5): 3084–3090.

View articletitled, Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

Hidden Epitopes Emerge in Secondary Influenza Virus-Specific CD8⁺ T Cell Reponses ¹

Paul G. Thomas; Scott A. Brown; Rachael Keating; Wen Yue; Melissa Y. Morris; Jenny So; Richard J. Webby; Peter C. Doherty

J Immunol (2007) 178 (5): 3091–3098.

View articletitled, Hidden Epitopes Emerge in Secondary Influenza Virus-Specific CD8<sup>+</sup> T Cell Reponses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel Antibody-Dependent Cellular Cytotoxicity Mechanism Involved in Defense against Malaria Requires Costimulation of Monocytes FcγRII and FcγRIII ¹

Ali Jafarshad; Morten H. Dziegiel; Rasmus Lundquist; Leif K. Nielsen; Subhash Singh; Pierre L. Druilhe

J Immunol (2007) 178 (5): 3099–3106.

View articletitled, A Novel Antibody-Dependent Cellular Cytotoxicity Mechanism Involved in Defense against Malaria Requires Costimulation of Monocytes FcγRII and FcγRIII<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dectin-1 Stimulation by Candida albicans Yeast or Zymosan Triggers NFAT Activation in Macrophages and Dendritic Cells ¹

Helen S. Goodridge; Randi M. Simmons; David M. Underhill

J Immunol (2007) 178 (5): 3107–3115.

View articletitled, Dectin-1 Stimulation by <em>Candida albicans</em> Yeast or Zymosan Triggers NFAT Activation in Macrophages and Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Human Peptidoglycan Recognition Proteins Require Zinc to Kill Both Gram-Positive and Gram-Negative Bacteria and Are Synergistic with Antibacterial Peptides ¹

Minhui Wang; Li-Hui Liu; Shiyong Wang; Xinna Li; Xiaofeng Lu; Dipika Gupta; Roman Dziarski

J Immunol (2007) 178 (5): 3116–3125.

View articletitled, Human Peptidoglycan Recognition Proteins Require Zinc to Kill Both Gram-Positive and Gram-Negative Bacteria and Are Synergistic with Antibacterial Peptides<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria ¹

Giuseppe Mancuso; Angelina Midiri; Carmelo Biondo; Concetta Beninati; Sebastiana Zummo; Roberta Galbo; Francesco Tomasello; Maria Gambuzza; Giancarlo Macrì; Alessia Ruggeri; Tomas Leanderson; Giuseppe Teti

J Immunol (2007) 178 (5): 3126–3133.

View articletitled, Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells ¹

Anja K. Mayer; Mario Muehmer; Jörg Mages; Katja Gueinzius; Christian Hess; Klaus Heeg; Robert Bals; Roland Lang; Alexander H. Dalpke

J Immunol (2007) 178 (5): 3134–3142.

View articletitled, Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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The Type I IFN Response to Infection with Mycobacterium tuberculosis Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis ¹

Sarah A. Stanley; James E. Johndrow; Paolo Manzanillo; Jeffery S. Cox

J Immunol (2007) 178 (5): 3143–3152.

View articletitled, The Type I IFN Response to Infection with <em>Mycobacterium tuberculosis</em> Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF)-Mediated Signaling Contributes to Innate Immune Responses in the Lung during Escherichia coli Pneumonia ¹

Samithamby Jeyaseelan; Scott K. Young; Michael B. Fessler; Yuhong Liu; Kenneth C. Malcolm; Masahiro Yamamoto; Shizuo Akira; G. Scott Worthen

J Immunol (2007) 178 (5): 3153–3160.

View articletitled, Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF)-Mediated Signaling Contributes to Innate Immune Responses in the Lung during <em>Escherichia coli</em> Pneumonia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and β₁ Integrin-Mediated Pathway ¹

Marie-Pierre Puissegur; Guillaume Lay; Martine Gilleron; Laure Botella; Jérôme Nigou; Hedia Marrakchi; Bernard Mari; Jean-Luc Duteyrat; Yann Guerardel; Laurent Kremer; Pascal Barbry; Germain Puzo; Frédéric Altare

J Immunol (2007) 178 (5): 3161–3169.

View articletitled, Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and β<sub>1</sub> Integrin-Mediated Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Role of Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing IFN-β in the Host Response to Pseudomonas aeruginosa Lung Infection in Mice ¹

Melanie R. Power; Bo Li; Masahiro Yamamoto; Shizuo Akira; Tong-Jun Lin

J Immunol (2007) 178 (5): 3170–3176.

View articletitled, A Role of Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing IFN-β in the Host Response to <em>Pseudomonas aeruginosa</em> Lung Infection in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Efficient Capture of Antibody Neutralized HIV-1 by Cells Expressing DC-SIGN and Transfer to CD4⁺ T Lymphocytes ¹^²

Thijs van Montfort; Alexey A. Nabatov; Teunis B. H. Geijtenbeek; Georgios Pollakis; William A. Paxton

J Immunol (2007) 178 (5): 3177–3185.

View articletitled, Efficient Capture of Antibody Neutralized HIV-1 by Cells Expressing DC-SIGN and Transfer to CD4<sup>+</sup> T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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TLR9 Expression and Function Is Abolished by the Cervical Cancer-Associated Human Papillomavirus Type 16 ¹

Uzma A. Hasan; Elizabeth Bates; Fumihiko Takeshita; Alexandra Biliato; Rosita Accardi; Veronique Bouvard; Mariam Mansour; Isabelle Vincent; Lutz Gissmann; Thomas Iftner; Mario Sideri; Frank Stubenrauch; Massimo Tommasino

J Immunol (2007) 178 (5): 3186–3197.

View articletitled, TLR9 Expression and Function Is Abolished by the Cervical Cancer-Associated Human Papillomavirus Type 16<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF-κB and Hypoxia-Inducible Factor-1α ¹

Dorothee Viemann; Marc Schmidt; Klaus Tenbrock; Sybille Schmid; Verena Müller; Kerstin Klimmek; Stephan Ludwig; Johannes Roth; Matthias Goebeler

J Immunol (2007) 178 (5): 3198–3207.

View articletitled, The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF-κB and Hypoxia-Inducible Factor-1α<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Retinoid-Related Orphan Receptor γ Controls Immunoglobulin Production and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen ¹

Stephen L. Tilley; Maisa Jaradat; Cliona Stapleton; Darlene Dixon; Xiaoyang Hua; Christopher J. Erikson; Joshua G. McCaskill; Kelly D. Chason; Grace Liao; Leigh Jania; Beverly H. Koller; Anton M. Jetten

J Immunol (2007) 178 (5): 3208–3218.

View articletitled, Retinoid-Related Orphan Receptor γ Controls Immunoglobulin Production and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR4 Hyperresponsiveness via Cell Surface Expression of Heat Shock Protein gp96 Potentiates Suppressive Function of Regulatory T Cells ¹

Jie Dai; Bei Liu; Soo Mun Ngoi; Shaoli Sun; Anthony T. Vella; Zihai Li

J Immunol (2007) 178 (5): 3219–3225.

View articletitled, TLR4 Hyperresponsiveness via Cell Surface Expression of Heat Shock Protein gp96 Potentiates Suppressive Function of Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia ¹

Ziye Sui; Lynn F. Sniderhan; Giovanni Schifitto; Richard P. Phipps; Harris A. Gelbard; Stephen Dewhurst; Sanjay B. Maggirwar

J Immunol (2007) 178 (5): 3226–3236.

View articletitled, Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TCR Signaling Antagonizes Rapid IP-10-Mediated Transendothelial Migration of Effector Memory CD4⁺ T Cells ¹

Thomas D. Manes; Stephen L. Shiao; Thomas J. Dengler; Jordan S. Pober

J Immunol (2007) 178 (5): 3237–3243.

View articletitled, TCR Signaling Antagonizes Rapid IP-10-Mediated Transendothelial Migration of Effector Memory CD4<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells ¹

Valérie Steenwinckel; Jamila Louahed; Ciriana Orabona; François Huaux; Guy Warnier; Andrew McKenzie; Dominique Lison; Roy Levitt; Jean-Christophe Renauld

J Immunol (2007) 178 (5): 3244–3251.

View articletitled, IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Rate of Increase in Circulating IL-7 and Loss of IL-7Rα Expression Differ in HIV-1 and HIV-2 Infections: Two Lymphopenic Diseases with Similar Hyperimmune Activation but Distinct Outcomes ¹

Adriana S. Albuquerque; Catarina S. Cortesão; Russell B. Foxall; Rui S. Soares; Rui M. M. Victorino; Ana E. Sousa

J Immunol (2007) 178 (5): 3252–3259.

View articletitled, Rate of Increase in Circulating IL-7 and Loss of IL-7Rα Expression Differ in HIV-1 and HIV-2 Infections: Two Lymphopenic Diseases with Similar Hyperimmune Activation but Distinct Outcomes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunotherapy of Tumors with Neuroimmune Ligand Capsaicin

Jacqueline Beltran; Amiya K. Ghosh; Sreyashi Basu

J Immunol (2007) 178 (5): 3260–3264.

View articletitled, Immunotherapy of Tumors with Neuroimmune Ligand Capsaicin

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HIV-Specific IL-10-Positive CD8⁺ T Cells Suppress Cytolysis and IL-2 Production by CD8⁺ T Cells ¹

Mohamed Elrefaei; Florence L. Ventura; Chris A. R. Baker; Richard Clark; David R. Bangsberg; Huyen Cao

J Immunol (2007) 178 (5): 3265–3271.

View articletitled, HIV-Specific IL-10-Positive CD8<sup>+</sup> T Cells Suppress Cytolysis and IL-2 Production by CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Expression Profile of FcγRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus ¹

Kaihong Su; Hengxuan Yang; Xinrui Li; Xiaoli Li; Andrew W. Gibson; John M. Cafardi; Tong Zhou; Jeffrey C. Edberg; Robert P. Kimberly

J Immunol (2007) 178 (5): 3272–3280.

View articletitled, Expression Profile of FcγRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Aberrant Expression of the Insulin-Like Growth Factor-1 Receptor by T Cells from Patients with Graves’ Disease May Carry Functional Consequences for Disease Pathogenesis ¹

Raymond S. Douglas; Andrew G. Gianoukakis; Shweta Kamat; Terry J. Smith

J Immunol (2007) 178 (5): 3281–3287.

View articletitled, Aberrant Expression of the Insulin-Like Growth Factor-1 Receptor by T Cells from Patients with Graves’ Disease May Carry Functional Consequences for Disease Pathogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Involvement of C-C Chemokine Ligand 2-CCR2 Interaction in Monocyte-Lineage Cell Recruitment of Normal Human Corneal Stroma ¹

Nobuyuki Ebihara; Satoru Yamagami; Seiichi Yokoo; Shiro Amano; Akira Murakami

J Immunol (2007) 178 (5): 3288–3292.

View articletitled, Involvement of C-C Chemokine Ligand 2-CCR2 Interaction in Monocyte-Lineage Cell Recruitment of Normal Human Corneal Stroma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Phenotype and Effector Function of CC Chemokine Receptor 9-Expressing Lymphocytes in Small Intestinal Crohn’s Disease ¹

Masayuki Saruta; Qi T. Yu; Armine Avanesyan; Phillip R. Fleshner; Stephan R. Targan; Konstantinos A. Papadakis

J Immunol (2007) 178 (5): 3293–3300.

View articletitled, Phenotype and Effector Function of CC Chemokine Receptor 9-Expressing Lymphocytes in Small Intestinal Crohn’s Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Enhanced Antitumor Responses Elicited by Combinatorial Protein Transfer of Chemotactic and Costimulatory Molecules ¹

Shanrong Liu; Deborah R. Breiter; Guoxing Zheng; Aoshuang Chen

J Immunol (2007) 178 (5): 3301–3306.

View articletitled, Enhanced Antitumor Responses Elicited by Combinatorial Protein Transfer of Chemotactic and Costimulatory Molecules<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis ¹

Maud Condomines; Dirk Hose; Pierre Raynaud; Michael Hundemer; John De Vos; Marion Baudard; Thomas Moehler; Véronique Pantesco; Marion Moos; Jean-François Schved; Jean-François Rossi; Thierry Rème; Hartmut Goldschmidt; Bernard Klein

J Immunol (2007) 178 (5): 3307–3315.

View articletitled, Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Critical Role for Allograft Inflammatory Factor-1 in the Pathogenesis of Rheumatoid Arthritis

Mizuho Kimura; Yutaka Kawahito; Hiroshi Obayashi; Mitsuhiro Ohta; Hirokazu Hara; Tetsuo Adachi; Daisaku Tokunaga; Tatsuya Hojo; Masahide Hamaguchi; Atsushi Omoto; Hidetaka Ishino; Makoto Wada; Masataka Kohno; Yasunori Tsubouchi; Toshikazu Yoshikawa

J Immunol (2007) 178 (5): 3316–3322.

View articletitled, A Critical Role for Allograft Inflammatory Factor-1 in the Pathogenesis of Rheumatoid Arthritis

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C3d Binding to the Myelin Oligodendrocyte Glycoprotein Results in an Exacerbated Experimental Autoimmune Encephalomyelitis ¹

Jean-François Jégou; Philippe Chan; Marie-Thérèse Schouft; Mark R. Griffiths; James W. Neal; Philippe Gasque; Hubert Vaudry; Marc Fontaine

J Immunol (2007) 178 (5): 3323–3331.

View articletitled, C3d Binding to the Myelin Oligodendrocyte Glycoprotein Results in an Exacerbated Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

S. N. Waggoner; M. W. Cruise; R. Kassel; Y. S. Hahn

J Immunol (2007) 178 (5): 3332.

View articletitled, gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway

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The engagement of activating FcγRs inhibits primate lentivirus replication in human macrophages

A. David; A. Sáez-Cirión; P. Versmisse; O. Malbec; B. Iannascoli; F. Herschke; M. Lucas; F. Barré-Sinoussi; J.-F. Mouscadet; M. Daëron; G. Pancino

J Immunol (2007) 178 (5): 3333.

View articletitled, The engagement of activating FcγRs inhibits primate lentivirus replication in human macrophages

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Induction of vascular leakage and blood pressure lowering through kinin release by a serine proteinase from Aeromonas sobria

T. Imamura; H. Kobayashi; R. Khan; H. Nitta; K. Okamoto

J Immunol (2007) 178 (5): 3333.

View articletitled, Induction of vascular leakage and blood pressure lowering through kinin release by a serine proteinase from <em>Aeromonas sobria</em>

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Urinary bladder epithelium antigen induces CD8⁺ T cell tolerance, activation, and autoimmune response

W. Liu; D. P. Evanoff; X. Chen; Y. Luo

J Immunol (2007) 178 (5): 3333.

View articletitled, Urinary bladder epithelium antigen induces CD8<sup>+</sup> T cell tolerance, activation, and autoimmune response

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HIV-1 Trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons

J. P. Norman; S. W. Perry; K. A. Kasischke; D. J. Volsky; H. A. Gelbard

J Immunol (2007) 178 (5): 3334.

View articletitled, HIV-1 <em>Trans</em> activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons

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Cover Image

Cover Image

On the cover: Tracks of naive T cell migration in a lymph node, imaged by two-photon laser scanning microscopy. Tracks start in blue and end in white. In similar imaging analysis, pertussis toxin-treated T cells showed severely compromised motility establishing an essential role for Gi signaling in promoting intranodal T cell movement. Okada, T., and J. G. Cyster. 2007. CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node. J. Immunol. 178: 2973–2978.
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