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Issues
15 April 2007
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
Comment on “Cutting Edge: Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells”
J Immunol (2007) 178 (8): 4705–4706.
Response to Comment on “Cutting Edge: Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells”
J Immunol (2007) 178 (8): 4706.
Comment on “Aberrant Regulation of Synovial T Cell Activation by Soluble Costimulatory Molecules in Rheumatoid Arthritis”
J Immunol (2007) 178 (8): 4708.
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Antigen Is Not Required for the Activation and Maintenance of Virus-Specific Memory CD8+ T Cells in the Lung Airways1
J Immunol (2007) 178 (8): 4721–4725.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
IL-7 Is Essential for the Development and the Persistence of Chronic Colitis1
Teruji Totsuka; Takanori Kanai; Yasuhiro Nemoto; Shin Makita; Ryuichi Okamoto; Kiichiro Tsuchiya; Mamoru Watanabe
J Immunol (2007) 178 (8): 4737–4748.
Regulation of Oxidative Stress Responses by Ataxia-Telangiectasia Mutated Is Required for T Cell Proliferation1
J Immunol (2007) 178 (8): 4757–4763.
An Essential Role for IL-18 in CD8 T Cell-Mediated Suppression of IgE Responses1
J Immunol (2007) 178 (8): 4771–4778.
Profound Enhancement of the IL-12/IL-18 Pathway of IFN-γ Secretion in Human CD8+ Memory T Cell Subsets via IL-151
J Immunol (2007) 178 (8): 4786–4792.
Spontaneous Autoreactive Memory B Cell Formation Driven by a High Frequency of Autoreactive CD4+ T Cells1
J Immunol (2007) 178 (8): 4793–4802.
The A Subunit of Type IIb Enterotoxin (LT-IIb) Suppresses the Proinflammatory Potential of the B Subunit and Its Ability to Recruit and Interact with TLR21
Shuang Liang; Min Wang; Kathy Triantafilou; Martha Triantafilou; Hesham F. Nawar; Michael W. Russell; Terry D. Connell; George Hajishengallis
J Immunol (2007) 178 (8): 4811–4819.
Differential Expression and Function of Phosphodiesterase 4 (PDE4) Subtypes in Human Primary CD4+ T Cells: Predominant Role of PDE4D1
J Immunol (2007) 178 (8): 4820–4831.
IFN-α-Induced Signal Transduction, Gene Expression, and Antitumor Activity of Immune Effector Cells Are Negatively Regulated by Suppressor of Cytokine Signaling Proteins1
Jason M. Zimmerer; Gregory B. Lesinski; Sri Vidya Kondadasula; Volodymyr I. Karpa; Amy Lehman; Abhik RayChaudhury; Brian Becknell; William E. Carson, III
J Immunol (2007) 178 (8): 4832–4845.
Glycoprotein 120 Binding to CXCR4 Causes p38-Dependent Primary T Cell Death That Is Facilitated by, but Does Not Require Cell-Associated CD4
Sergey A. Trushin; Alicia Algeciras-Schimnich; Stacey R. Vlahakis; Gary D. Bren; Sarah Warren; David J. Schnepple; Andrew D. Badley
J Immunol (2007) 178 (8): 4846–4853.
Aggregated Ursolic Acid, a Natural Triterpenoid, Induces IL-1β Release from Murine Peritoneal Macrophages: Role of CD361
Yasutaka Ikeda; Akira Murakami; Yoshinori Fujimura; Hirofumi Tachibana; Koji Yamada; Daisaku Masuda; Ken-ichi Hirano; Shizuya Yamashita; Hajime Ohigashi
J Immunol (2007) 178 (8): 4854–4864.
T Cell Repertoire Diversity Is Required for Relapses in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis1
Nicolas Fazilleau; Cécile Delarasse; Iris Motta; Simon Fillatreau; Marie-Lise Gougeon; Philippe Kourilsky; Danielle Pham-Dinh; Jean M. Kanellopoulos
J Immunol (2007) 178 (8): 4865–4875.
β1-Adrenergic Receptors on Immune Cells Impair Innate Defenses against Listeria
J Immunol (2007) 178 (8): 4876–4884.
Stat3 and Stat4 Direct Development of IL-17-Secreting Th Cells1
Anubhav N. Mathur; Hua-Chen Chang; Dimitrios G. Zisoulis; Gretta L. Stritesky; Qing Yu; John T. O’Malley; Reuben Kapur; David E. Levy; Geoffrey S. Kansas; Mark H. Kaplan
J Immunol (2007) 178 (8): 4901–4907.
TLR2-Mediated Survival of Staphylococcus aureus in Macrophages: A Novel Bacterial Strategy against Host Innate Immunity1
J Immunol (2007) 178 (8): 4917–4925.
Schnurri-2 Controls Memory Th1 and Th2 Cell Numbers In Vivo1
Motoko Y. Kimura; Chiaki Iwamura; Akane Suzuki; Takako Miki; Akihiro Hasegawa; Kaoru Sugaya; Masakatsu Yamashita; Shunsuke Ishii; Toshinori Nakayama
J Immunol (2007) 178 (8): 4926–4936.
Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation1
Shin Makita; Takanori Kanai; Yasuhiro Nemoto; Teruji Totsuka; Ryuichi Okamoto; Kiichiro Tsuchiya; Masafumi Yamamoto; Hiroshi Kiyono; Mamoru Watanabe
J Immunol (2007) 178 (8): 4937–4946.
CD56brightCD16− Killer Ig-Like Receptor− NK Cells Display Longer Telomeres and Acquire Features of CD56dim NK Cells upon Activation1
Chiara Romagnani; Kerstin Juelke; Michela Falco; Barbara Morandi; Antonella D’Agostino; Roberta Costa; Giovanni Ratto; Giuseppe Forte; Paolo Carrega; Gabrielle Lui; Romana Conte; Till Strowig; Alessandro Moretta; Christian Münz; Andreas Thiel; Lorenzo Moretta; Guido Ferlazzo
J Immunol (2007) 178 (8): 4947–4955.
A Unique Thymic Fibroblast Population Revealed by the Monoclonal Antibody MTS-151
Daniel H. D. Gray; Dedreia Tull; Tomoo Ueno; Natalie Seach; Brendan J. Classon; Ann Chidgey; Malcolm J. McConville; Richard L. Boyd
J Immunol (2007) 178 (8): 4956–4965.
Dermal Fibroblasts Induce Maturation of Dendritic Cells1
Anja Saalbach; Claudia Klein; Jonathan Sleeman; Ulrich Sack; Friederike Kauer; Carl Gebhardt; Marco Averbeck; Ulf Anderegg; Jan C. Simon
J Immunol (2007) 178 (8): 4966–4974.
Quantitative Network Signal Combinations Downstream of TCR Activation Can Predict IL-2 Production Response1
J Immunol (2007) 178 (8): 4984–4992.
Increased Hyperoxia-Induced Mortality and Acute Lung Injury in IL-13 Null Mice1
J Immunol (2007) 178 (8): 4993–5000.
Protective Role of Macrophages in Noninflammatory Lung Injury Caused by Selective Ablation of Alveolar Epithelial Type II Cells1
J Immunol (2007) 178 (8): 5001–5009.
Germinal Center Helper T Cells Are Dual Functional Regulatory Cells with Suppressive Activity to Conventional CD4+ T Cells
J Immunol (2007) 178 (8): 5010–5017.
β-Catenin Regulates Positive Selection of Thymocytes but Not Lineage Commitment1
J Immunol (2007) 178 (8): 5028–5034.
Autoantigen-B Cell Antigen Receptor Interactions That Regulate Expression of B Cell Antigen Receptor Loci1
J Immunol (2007) 178 (8): 5035–5047.
A Critical Role for p53 in the Control of NF-κB-Dependent Gene Expression in TLR4-Stimulated Dendritic Cells Exposed to Genistein1
Nathalie Dijsselbloem; Stanislas Goriely; Valentina Albarani; Sarah Gerlo; Sarah Francoz; Jean-Christophe Marine; Michel Goldman; Guy Haegeman; Wim Vanden Berghe
J Immunol (2007) 178 (8): 5048–5057.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Both the Suppressor of Cytokine Signaling 1 (SOCS-1) Kinase Inhibitory Region and SOCS-1 Mimetic Bind to JAK2 Autophosphorylation Site: Implications for the Development of a SOCS-1 Antagonist1
Lilian W. Waiboci; Chulbul M. Ahmed; Mustafa G. Mujtaba; Lawrence O. Flowers; James P. Martin; Mohammed I. Haider; Howard M. Johnson
J Immunol (2007) 178 (8): 5058–5068.
IMMUNOGENETICS
Description and Mapping of the Resistance of DBA/2 Mice to TNF-Induced Lethal Shock1
Ben Wielockx; Jan Staelens; Leen Puimège; Ineke Vanlaere; Maarten Van Roy; Philippe van Lint; Frans Van Roy; Claude Libert
J Immunol (2007) 178 (8): 5069–5075.
HOST DEFENSE
IL-28 Elicits Antitumor Responses against Murine Fibrosarcoma
Muneo Numasaki; Masatoshi Tagawa; Fumi Iwata; Takashi Suzuki; Akira Nakamura; Masahiro Okada; Yoichiro Iwakura; Setsuya Aiba; Mutsuo Yamaya
J Immunol (2007) 178 (8): 5086–5098.
A Novel Mode of Action for a Microbial-Derived Immunotoxin: The Cytolethal Distending Toxin Subunit B Exhibits Phosphatidylinositol 3,4,5-Triphosphate Phosphatase Activity1
Bruce J. Shenker; Mensur Dlakić; Lisa P. Walker; Dave Besack; Eileen Jaffe; Ed LaBelle; Kathleen Boesze-Battaglia
J Immunol (2007) 178 (8): 5099–5108.
Increasing the Recruitment of Neutrophils to the Site of Infection Dramatically Attenuates Borrelia burgdorferi Infectivity1
J Immunol (2007) 178 (8): 5109–5115.
MyD88 Is Required for the Formation of Long-Term Humoral Immunity to Virus Infection1
J Immunol (2007) 178 (8): 5124–5131.
Thiocyanate Transport in Resting and IL-4-Stimulated Human Bronchial Epithelial Cells: Role of Pendrin and Anion Channels1
Nicoletta Pedemonte; Emanuela Caci; Elvira Sondo; Antonella Caputo; Kerry Rhoden; Ulrich Pfeffer; Michele Di Candia; Roberto Bandettini; Roberto Ravazzolo; Olga Zegarra-Moran; Luis J. V. Galietta
J Immunol (2007) 178 (8): 5144–5153.
Toxoplasma gondii Dysregulates IFN-γ-Inducible Gene Expression in Human Fibroblasts: Insights from a Genome-Wide Transcriptional Profiling1
J Immunol (2007) 178 (8): 5154–5165.
MyD88-Dependent Activation of B220−CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection1
J Immunol (2007) 178 (8): 5182–5191.
TLR3 Is Essential for the Induction of Protective Immunity against Punta Toro Virus Infection by the Double-Stranded RNA (dsRNA), Poly(I:C12U), but not Poly(I:C): Differential Recognition of Synthetic dsRNA Molecules1
Brian B. Gowen; Min-Hui Wong; Kie-Hoon Jung; Andrew B. Sanders; William M. Mitchell; Lena Alexopoulou; Richard A. Flavell; Robert W. Sidwell
J Immunol (2007) 178 (8): 5200–5208.
Dynamic Relationship between IFN-γ and IL-2 Profile of Mycobacterium tuberculosis-Specific T Cells and Antigen Load1
Kerry A. Millington; John A. Innes; Sarah Hackforth; Timothy S. C. Hinks; Jonathan J. Deeks; Davinder P. S. Dosanjh; Valerie Guyot-Revol; Rubamalaar Gunatheesan; Paul Klenerman; Ajit Lalvani
J Immunol (2007) 178 (8): 5217–5226.
CD8+ T Cell Dysfunction and Increase in Murine Gammaherpesvirus Latent Viral Burden in the Absence of 4-1BB Ligand1
J Immunol (2007) 178 (8): 5227–5236.
INFLAMMATION
Mold Allergen, Pen c 13, Induces IL-8 Expression in Human Airway Epithelial Cells by Activating Protease-Activated Receptor 1 and 21
J Immunol (2007) 178 (8): 5237–5244.
IFN-γ Induces Cysteinyl Leukotriene Receptor 2 Expression and Enhances the Responsiveness of Human Endothelial Cells to Cysteinyl Leukotrienes1
Grzegorz Woszczek; Li-Yuan Chen; Sahrudaya Nagineni; Sara Alsaaty; Anya Harry; Carolea Logun; Rafal Pawliczak; James H. Shelhamer
J Immunol (2007) 178 (8): 5262–5270.
Aluminum Hydroxide Adjuvants Activate Caspase-1 and Induce IL-1β and IL-18 Release1
J Immunol (2007) 178 (8): 5271–5276.
Inflammatory Reactive Oxygen Species-Mediated Hemopoietic Suppression in Fancc-Deficient Mice1
Daniel P. Sejas; Reena Rani; Yuhui Qiu; Xiaoling Zhang; Sara R. Fagerlie; Hiroyasu Nakano; David A. Williams; Qishen Pang
J Immunol (2007) 178 (8): 5277–5287.
Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis1
Jonathan A. Fallowfield; Masashi Mizuno; Timothy J. Kendall; Christothea M. Constandinou; R. Christopher Benyon; Jeremy S. Duffield; John P. Iredale
J Immunol (2007) 178 (8): 5288–5295.
Chemokine Receptor CCR2 but Not CCR5 or CCR6 Mediates the Increase in Pulmonary Dendritic Cells during Allergic Airway Inflammation1
Lander J. Robays; Tania Maes; Serge Lebecque; Sergio A. Lira; William A. Kuziel; Guy G. Brusselle; Guy F. Joos; Karim V. Vermaelen
J Immunol (2007) 178 (8): 5305–5311.
Knockout of Mkp-1 Enhances the Host Inflammatory Responses to Gram-Positive Bacteria1
Xianxi Wang; Xiaomei Meng; Joshua R. Kuhlman; Leif D. Nelin; Kathleen K. Nicol; B. Keith English; Yusen Liu
J Immunol (2007) 178 (8): 5312–5320.
CLINICAL IMMUNOLOGY
The Lymphocytic Infiltration in Calcific Aortic Stenosis Predominantly Consists of Clonally Expanded T Cells1
Henry D. Wu; Mathew S. Maurer; Richard A. Friedman; Charles C. Marboe; Elena M. Ruiz-Vazquez; Rajasekhar Ramakrishnan; Allan Schwartz; M. David Tilson; Allan S. Stewart; Robert Winchester
J Immunol (2007) 178 (8): 5329–5339.
Potential Role for IL-7 in Fas-Mediated T Cell Apoptosis During HIV Infection1
Caroline Fluur; Angelo De Milito; Terry J. Fry; Nancy Vivar; Liv Eidsmo; Ann Atlas; Cristina Federici; Paola Matarrese; Mariantonia Logozzi; Eva Rajnavölgyi; Crystal L. Mackall; Stefano Fais; Francesca Chiodi; Bence Rethi
J Immunol (2007) 178 (8): 5340–5350.
Overexpression of Activation-Induced Cytidine Deaminase in B Cells Is Associated with Production of Highly Pathogenic Autoantibodies1
Hui-Chen Hsu; Yalei Wu; PingAr Yang; Qi Wu; Godwin Job; Jian Chen; John Wang; Mary Ann V. Accavitti-Loper; William E. Grizzle; Robert H. Carter; John D. Mountz
J Immunol (2007) 178 (8): 5357–5365.
Inhibition of Transmethylation Down-Regulates CD4 T Cell Activation and Curtails Development of Autoimmunity in a Model System
Brian R. Lawson; Yulia Manenkova; Jasimuddin Ahamed; Xiaoru Chen; Jian-Ping Zou; Roberto Baccala; Argyrios N. Theofilopoulos; Chong Yuan
J Immunol (2007) 178 (8): 5366–5374.
Airway Exposure Levels of Lipopolysaccharide Determine Type 1 versus Type 2 Experimental Asthma1
Yoon-Keun Kim; Sun-Young Oh; Seong Gyu Jeon; Heung-Woo Park; Soo-Yeon Lee; Eun-Young Chun; Boram Bang; Hyun-Seung Lee; Min-Hee Oh; You-Sun Kim; Jong-Hoon Kim; Yong Song Gho; Sang-Heon Cho; Kyung-Up Min; You-Young Kim; Zhou Zhu
J Immunol (2007) 178 (8): 5375–5382.
Amelioration of Experimental Autoimmune Myasthenia Gravis in Rats by Neonatal FcR Blockade
Liming Liu; Ana Maria Garcia; Helen Santoro; Yixia Zhang; Kevin McDonnell; Jennifer Dumont; Alan Bitonti
J Immunol (2007) 178 (8): 5390–5398.
CORRECTIONS
Active participation of antigen nonspecific lymphoid cells in immune-mediated inflammation
J Immunol (2007) 178 (8): 5399.
Cowpox virus evades CTL recognition and inhibits the intracellular transport of MHC class I molecules
J Immunol (2007) 178 (8): 5401.
Epigenetic and transcriptional programs lead to default IFN-γ production by γδ T cells
L. Chen; W. He; S. T. Kim; J. Tao; Y. Gao; H. Chi; A. M. Intlekofer; B. Harvey; S. L. Reiner; Z. Yin; R. A. Flavell; J. Craft
J Immunol (2007) 178 (8): 5401.
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Cover Image
Cover Image
On the cover: The mAb MTS-15 recognizes a glycosphingolipid shed from the cell surface of reticular fibroblasts in the thymus and spleen. Immunofluorescent staining of cryosectioned mouse spleen with MTS-15 (green), anti-CD31 (red), and anti-CD45 (blue) imaged by laser confocal microscopy. Gray, D. H. D., D. Tull, T. Ueno, N. Seach, B. J. Classon, A. Chidgey, M. J. McConville, and R. L. Boyd. 2007. A unique thymic fibroblast population revealed by the monoclonal antibody MTS-151. J. Immunol. 178: 4956–4965.
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