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Issues
15 August 2007
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
BRIEF REVIEWS
Structure and Function: Heat Shock Proteins and Adaptive Immunity1
J Immunol (2007) 179 (4): 2035–2040.
CUTTING EDGE
Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25− T Cells1
Sabine Dominitzki; Massimo C. Fantini; Clemens Neufert; Alexei Nikolaev; Peter R. Galle; Jürgen Scheller; Giovanni Monteleone; Stefan Rose-John; Markus F. Neurath; Christoph Becker
J Immunol (2007) 179 (4): 2041–2045.
Cutting Edge: Primary B Lymphocytes Preferentially Expand Allogeneic FoxP3+ CD4 T Cells
J Immunol (2007) 179 (4): 2046–2050.
Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells1
J Immunol (2007) 179 (4): 2051–2054.
Cutting Edge: A Hypomorphic Mutation in Igβ (CD79b) in a Patient with Immunodeficiency and a Leaky Defect in B Cell Development1
J Immunol (2007) 179 (4): 2055–2059.
Cutting Edge: Vitamin D-Mediated Human Antimicrobial Activity against Mycobacterium tuberculosis Is Dependent on the Induction of Cathelicidin1
J Immunol (2007) 179 (4): 2060–2063.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
A Pegylated Derivative of α-Galactosylceramide Exhibits Improved Biological Properties
J Immunol (2007) 179 (4): 2065–2073.
Altered B:9–23 Insulin, When Administered Intranasally with Cholera Toxin Adjuvant, Suppresses the Expression of Insulin Autoantibodies and Prevents Diabetes1
Masakazu Kobayashi; Norio Abiru; Takeshi Arakawa; Keiko Fukushima; Hongbo Zhou; Eiji Kawasaki; Hironori Yamasaki; Edwin Liu; Dongmei Miao; F. Susan Wong; George S. Eisenbarth; Katsumi Eguchi
J Immunol (2007) 179 (4): 2082–2088.
The Adaptor Molecule CIN85 Regulates Syk Tyrosine Kinase Level by Activating the Ubiquitin-Proteasome Degradation Pathway1
Giovanna Peruzzi; Rosa Molfetta; Francesca Gasparrini; Laura Vian; Stefania Morrone; Mario Piccoli; Luigi Frati; Angela Santoni; Rossella Paolini
J Immunol (2007) 179 (4): 2089–2096.
NK Cell Lysis of HIV-1-Infected Autologous CD4 Primary T Cells: Requirement for IFN-Mediated NK Activation by Plasmacytoid Dendritic Cells1
J Immunol (2007) 179 (4): 2097–2104.
Role of Direct Effects of IFN-γ on T Cells in the Regulation of CD8 T Cell Homeostasis1
J Immunol (2007) 179 (4): 2115–2125.
In Vivo Antigen Stability Affects DNA Vaccine Immunogenicity
Adriaan D. Bins; Monika C. Wolkers; Marly D. van den Boom; John B. A. G. Haanen; Ton N. M. Schumacher
J Immunol (2007) 179 (4): 2126–2133.
Enhancement of Human Melanoma Antigen Expression by IFN-β1
Ian S. Dunn; Timothy J. Haggerty; Michihiro Kono; Paul J. Durda; David Butera; David B. Macdonald; Elizabeth M. Benson; Lenora B. Rose; James T. Kurnick
J Immunol (2007) 179 (4): 2134–2142.
Age-Dependent TCR Revision Mediated by Interaction between αβ TCR and Self-Antigens
J Immunol (2007) 179 (4): 2163–2169.
Selective Expansion of Foxp3-Positive Regulatory T Cells and Immunosuppression by Suppressors of Cytokine Signaling 3-Deficient Dendritic Cells1
Yumiko Matsumura; Takashi Kobayashi; Kenji Ichiyama; Ryoko Yoshida; Masayuki Hashimoto; Tomohito Takimoto; Kentaro Tanaka; Takatoshi Chinen; Takashi Shichita; Tony Wyss-Coray; Katsuaki Sato; Akihiko Yoshimura
J Immunol (2007) 179 (4): 2170–2179.
Acute Rejection of Allografted CTL-Susceptible Leukemia Cells from Perforin/Fas Ligand Double-Deficient Mice1
Hayahito Nomi; Junko Tashiro-Yamaji; Yumiko Yamamoto; Sayako Miura-Takeda; Masako Miyoshi-Higashino; Takeshi Takahashi; Haruhito Azuma; Haruhiko Ueda; Yoji Katsuoka; Takahiro Kubota; Ryotaro Yoshida
J Immunol (2007) 179 (4): 2180–2186.
Phospholipase Cβ Is Critical for T Cell Chemotaxis1
Tami L. Bach; Qing-Min Chen; Wesley T. Kerr; Yanfeng Wang; Lurong Lian; John K. Choi; Dianqing Wu; Marcelo G. Kazanietz; Gary A. Koretzky; Sally Zigmond; Charles S. Abrams
J Immunol (2007) 179 (4): 2223–2227.
Multiple Constraints at the Level of TCRα Rearrangement Impact Vα14i NKT Cell Development1
J Immunol (2007) 179 (4): 2228–2234.
MHC Class II+ Exosomes in Plasma Suppress Inflammation in an Antigen-Specific and Fas Ligand/Fas-Dependent Manner1
J Immunol (2007) 179 (4): 2235–2241.
Effective Treatment of Inflammatory Disease Models with Exosomes Derived from Dendritic Cells Genetically Modified to Express IL-41
J Immunol (2007) 179 (4): 2242–2249.
TCR Affinity Promotes CD8+ T Cell Expansion by Regulating Survival1
J Immunol (2007) 179 (4): 2250–2260.
Class IA Phosphoinositide 3-Kinase Modulates Basal Lymphocyte Motility in the Lymph Node1
J Immunol (2007) 179 (4): 2261–2269.
The Recirculating B Cell Pool Contains Two Functionally Distinct, Long-Lived, Posttransitional, Follicular B Cell Populations1
J Immunol (2007) 179 (4): 2270–2281.
TACI Is Required for Efficient Plasma Cell Differentiation in Response to T-Independent Type 2 Antigens1
J Immunol (2007) 179 (4): 2282–2288.
CCR5 Blockade Modulates Inflammation and Alloimmunity in Primates1
Carsten Schröder; Richard N. Pierson, III; Bao-Ngoc H. Nguyen; Douglas W. Kawka; Laurence B. Peterson; Guosheng Wu; Tianshu Zhang; Martin S. Springer; Sal J. Siciliano; Susan Iliff; Julia M. Ayala; Min Lu; John S. Mudgett; Kathy Lyons; Sander G. Mills; Geraldine G. Miller; Irwin I. Singer; Agnes M. Azimzadeh; Julie A. DeMartino
J Immunol (2007) 179 (4): 2289–2299.
A Single Early Activation of Invariant NK T Cells Confers Long-Term Protection against Collagen-Induced Arthritis in a Ligand-Specific Manner1
Ken Coppieters; Katrien Van Beneden; Peggy Jacques; Pieter Dewint; Ann Vervloet; Bert Vander Cruyssen; Serge Van Calenbergh; Guangwu Chen; Richard W. Franck; Gust Verbruggen; Dieter Deforce; Patrick Matthys; Moriya Tsuji; Pieter Rottiers; Dirk Elewaut
J Immunol (2007) 179 (4): 2300–2309.
Molecular and Cellular Requirements for Enhanced Antigen Cross-Presentation to CD8 Cytotoxic T Lymphocytes1
J Immunol (2007) 179 (4): 2310–2317.
Up-Regulation of Bcl-2 through ERK Phosphorylation Is Associated with Human Macrophage Survival in an Estrogen Microenvironment1
J Immunol (2007) 179 (4): 2330–2338.
CTLs Contain and Use Intracellular Stores of FasL Distinct from Cytolytic Granules1
J Immunol (2007) 179 (4): 2339–2348.
Fimbrial Proteins of Porphyromonas gingivalis Mediate In Vivo Virulence and Exploit TLR2 and Complement Receptor 3 to Persist in Macrophages1
Min Wang; Muhamad-Ali K. Shakhatreh; Deanna James; Shuang Liang; So-ichiro Nishiyama; Fuminobu Yoshimura; Donald R. Demuth; George Hajishengallis
J Immunol (2007) 179 (4): 2349–2358.
Complement Receptor 3 Blockade Promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo1
J Immunol (2007) 179 (4): 2359–2367.
In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration1
Laurent Derré; Marc Bruyninx; Petra Baumgaertner; Estelle Devevre; Patricia Corthesy; Cédric Touvrey; Yolanda D. Mahnke; Hanspeter Pircher; Verena Voelter; Pedro Romero; Daniel E. Speiser; Nathalie Rufer
J Immunol (2007) 179 (4): 2368–2379.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
O-Glycosylated Human MUC1 Repeats Are Processed In Vitro by Immunoproteasomes1
J Immunol (2007) 179 (4): 2380–2388.
IL-10 Is Excluded from the Functional Cytokine Memory of Human CD4+ Memory T Lymphocytes1
Jun Dong; Claudia Ivascu; Hyun-Dong Chang; Peihua Wu; Roberta Angeli; Laura Maggi; Florian Eckhardt; Lars Tykocinski; Carolina Haefliger; Beate Möwes; Jochen Sieper; Andreas Radbruch; Francesco Annunziato; Andreas Thiel
J Immunol (2007) 179 (4): 2389–2396.
Signal-Transducing Adaptor Protein-2 Regulates Integrin-Mediated T Cell Adhesion through Protein Degradation of Focal Adhesion Kinase1
Yuichi Sekine; Satoshi Tsuji; Osamu Ikeda; Kenji Sugiyma; Kenji Oritani; Kazuya Shimoda; Ryuta Muromoto; Norihiko Ohbayashi; Akihiko Yoshimura; Tadashi Matsuda
J Immunol (2007) 179 (4): 2397–2407.
Human Anti-CXCR4 Antibodies Undergo VH Replacement, Exhibit Functional V-Region Sulfation, and Define CXCR4 Antigenic Heterogeneity1
J Immunol (2007) 179 (4): 2408–2418.
IMMUNOGENETICS
Sequence and Characterization of the Ig Heavy Chain Constant and Partial Variable Region of the Mouse Strain 129S11
Ida Retter; Christophe Chevillard; Maren Scharfe; Ansgar Conrad; Martin Hafner; Tschong-Hun Im; Monika Ludewig; Gabriele Nordsiek; Simone Severitt; Stephanie Thies; America Mauhar; Helmut Blöcker; Werner Müller; Roy Riblet
J Immunol (2007) 179 (4): 2419–2427.
BXSB/long-lived Is a Recombinant Inbred Strain Containing Powerful Disease Suppressor Loci1
Michelle E. K. Haywood; Luisa Gabriel; S. Jane Rose; Nicola J. Rogers; Shozo Izui; Bernard J. Morley
J Immunol (2007) 179 (4): 2428–2434.
HOST DEFENSE
Filarial Parasites Induce NK Cell Activation, Type 1 and Type 2 Cytokine Secretion, and Subsequent Apoptotic Cell Death1
J Immunol (2007) 179 (4): 2445–2456.
A Role for IFN-γ from Antigen-Specific CD8+ T Cells in Protective Immunity to Listeria monocytogenes1
J Immunol (2007) 179 (4): 2457–2466.
Icsbp1/IRF-8 Is Required for Innate and Adaptive Immune Responses against Intracellular Pathogens1
J Immunol (2007) 179 (4): 2467–2476.
IFN-γ-Producing Dendritic Cells Are Important for Priming of Gut Intraepithelial Lymphocyte Response Against Intracellular Parasitic Infection1
J Immunol (2007) 179 (4): 2485–2492.
Fusobacterium nucleatum Induces Fetal Death in Mice via Stimulation of TLR4-Mediated Placental Inflammatory Response1
J Immunol (2007) 179 (4): 2501–2508.
C-Terminal Tail Phosphorylation of N-Formyl Peptide Receptor: Differential Recognition of Two Neutrophil Chemoattractant Receptors by Monoclonal Antibodies NFPR1 and NFPR21
Marcia Riesselman; Heini M. Miettinen; Jeannie M. Gripentrog; Connie I. Lord; Brendan Mumey; Edward A. Dratz; Jamal Stie; Ross M. Taylor; Algirdas J. Jesaitis
J Immunol (2007) 179 (4): 2520–2531.
Porphyromonas gingivalis Selectively Up-Regulates the HIV-1 Coreceptor CCR5 in Oral Keratinocytes1
J Immunol (2007) 179 (4): 2542–2550.
INFLAMMATION
IL-1 Receptor Accessory Protein and ST2 Comprise the IL-33 Receptor Complex
Alissa A. Chackerian; Elizabeth R. Oldham; Erin E. Murphy; Jochen Schmitz; Stefan Pflanz; Robert A. Kastelein
J Immunol (2007) 179 (4): 2551–2555.
Human Blood-Brain Barrier Disruption by Retroviral-Infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-Junction Disorganization1
Philippe Vicente Afonso; Simona Ozden; Marie-Christine Prevost; Christine Schmitt; Danielle Seilhean; Babette Weksler; Pierre-Olivier Couraud; Antoine Gessain; Ignacio Andres Romero; Pierre-Emmanuel Ceccaldi
J Immunol (2007) 179 (4): 2576–2583.
Cellular and Humoral Autoreactivity in Idiopathic Pulmonary Fibrosis1
Carol A. Feghali-Bostwick; Christopher G. Tsai; Vincent G. Valentine; Stephen Kantrow; Michael W. Stoner; Joseph M. Pilewski; Aneal Gadgil; M. Patricia George; Kevin F. Gibson; Augustine M. K. Choi; Naftali Kaminski; Yingze Zhang; Steven R. Duncan
J Immunol (2007) 179 (4): 2592–2599.
Properdin Can Initiate Complement Activation by Binding Specific Target Surfaces and Providing a Platform for De Novo Convertase Assembly1
J Immunol (2007) 179 (4): 2600–2608.
CLINICAL IMMUNOLOGY
Unchecked CD70 Expression on T Cells Lowers Threshold for T Cell Activation in Rheumatoid Arthritis1
J Immunol (2007) 179 (4): 2609–2615.
Functional T Cell Responses to Tumor Antigens in Breast Cancer Patients Have a Distinct Phenotype and Cytokine Signature1
Margaret Inokuma; Corazon dela Rosa; Charles Schmitt; Perry Haaland; Janet Siebert; Douglas Petry; MengXiang Tang; Maria A. Suni; Smita A. Ghanekar; Daiva Gladding; John F. Dunne; Vernon C. Maino; Mary L. Disis; Holden T. Maecker
J Immunol (2007) 179 (4): 2627–2633.
Baseline Viral Load and Immune Activation Determine the Extent of Reconstitution of Innate Immune Effectors in HIV-1-Infected Subjects Undergoing Antiretroviral Treatment12
Jihed Chehimi; Livio Azzoni; Matthew Farabaugh; Shenoa A. Creer; Costin Tomescu; Aidan Hancock; Agnes Mackiewicz; Lara D’Alessandro; Smita Ghanekar; Andrea S. Foulkes; Karam Mounzer; Jay Kostman; Luis J. Montaner
J Immunol (2007) 179 (4): 2642–2650.
CORRECTIONS
Diversity in the acute CD8 T cell response to vaccinia virus in humans
J Immunol (2007) 179 (4): 2658.
Episodes of natural selection shaped the interactions of IgA-Fc with FcαRI and bacterial decoy proteins
J Immunol (2007) 179 (4): 2659.
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Cover Image
Cover Image
On the cover: Model of cell penetrating STAT-6 binding peptide (STAT-6-IP) in which the HIV-TAT-derived PTD4 protein transduction domain was fused to seven amino acids surrounding the phosphotyrosine residue of STAT-6. The peptide phosphotyrosine residue (blue), predicted to bind to phosphorylated STAT-6, is oriented to the top. The model was generated using HyperChem 8.0 software. McCusker, C. T., Y. Wang, J. Shan, M. W. Kinyanjui, A. Villeneuve, H. Michael, and E. D. Fixman. 2007. Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide. J. Immunol. 179: 2556–2564.
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