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Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer’s Disease Patients1
Amanda K. Damjanovic; Yinhua Yang; Ronald Glaser; Janice K. Kiecolt-Glaser; Huy Nguyen; Bryon Laskowski; Yixiao Zou; David Q. Beversdorf; Nan-ping Weng
J Immunol (2007) 179 (6): 4249–4254.
IFN-α Is Not Sufficient to Drive Th1 Development Due to Lack of Stable T-bet Expression1
J Immunol (2007) 179 (6): 3792–3803.
Atorvastatin Inhibits T Cell Activation through 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase without Decreasing Cholesterol Synthesis1
Norbert Blank; Martin Schiller; Stefan Krienke; Freja Busse; Birgit Schätz; Anthony D. Ho; Joachim R. Kalden; Hanns-Martin Lorenz
J Immunol (2007) 179 (6): 3613–3621.
Reciprocal NFAT1 and NFAT2 Nuclear Localization in CD8+ Anergic T Cells Is Regulated by Suboptimal Calcium Signaling1
J Immunol (2007) 179 (6): 3734–3741.
Lung Macrophages Serve as Obligatory Intermediate between Blood Monocytes and Alveolar Macrophages1
J Immunol (2007) 179 (6): 3488–3494.
A Soluble Form of Lymphocyte Activation Gene-3 (IMP321) Induces Activation of a Large Range of Human Effector Cytotoxic Cells
J Immunol (2007) 179 (6): 4202–4211.
IL-17 Enhances Chemokine Gene Expression through mRNA Stabilization1
J Immunol (2007) 179 (6): 4135–4141.
Metalloproteinases Shed TREM-1 Ectodomain from Lipopolysaccharide-Stimulated Human Monocytes1
Vanesa Gómez-Piña; Alessandra Soares-Schanoski; Alexandro Rodríguez-Rojas; Carlos del Fresno; Felipe García; María Teresa Vallejo-Cremades; Irene Fernández-Ruiz; Francisco Arnalich; Pablo Fuentes-Prior; Eduardo López-Collazo
J Immunol (2007) 179 (6): 4065–4073.
IL-21 Induces Apoptosis of Antigen-Specific CD8+ T Lymphocytes1
J Immunol (2007) 179 (6): 3596–3603.
Herpesvirus Chemokine-Binding Glycoprotein G (gG) Efficiently Inhibits Neutrophil Chemotaxis In Vitro and In Vivo1
J Immunol (2007) 179 (6): 4161–4169.
The Induction and Persistence of T Cell IFN-γ Responses after Vaccination or Natural Exposure Is Suppressed by Plasmodium falciparum1
Philip Bejon; Jedidah Mwacharo; Oscar Kai; Stephen Todryk; Sheila Keating; Brett Lowe; Trudie Lang; Tabitha W. Mwangi; Sarah C. Gilbert; Norbert Peshu; Kevin Marsh; Adrian V. S. Hill
J Immunol (2007) 179 (6): 4193–4201.
A Novel Mouse Model for Invariant NKT Cell Study1
Hiroshi Wakao; Hiroshi Kawamoto; Sakura Sakata; Kimiko Inoue; Atsuo Ogura; Rika Wakao; Atsushi Oda; Hiroyoshi Fujita
J Immunol (2007) 179 (6): 3888–3895.
IL-23 Enhances Host Defense against Vaccinia Virus Infection Via a Mechanism Partly Involving IL-171
Shunsuke Kohyama; Satoshi Ohno; Akihiro Isoda; Osamu Moriya; Maria Laura Belladonna; Hidenori Hayashi; Yoichiro Iwakura; Takayuki Yoshimoto; Toshitaka Akatsuka; Masanori Matsui
J Immunol (2007) 179 (6): 3917–3925.
TGF-β1 Variants in Chronic Beryllium Disease and Sarcoidosis1
Alexas C. Jonth; Lori Silveira; Tasha E. Fingerlin; Hiroe Sato; Julie C. Luby; Kenneth I. Welsh; Cecile S. Rose; Lee S. Newman; Roland M. du Bois; Lisa A. Maier; The ACCESS Group
J Immunol (2007) 179 (6): 4255–4262.
Down-Modulation of CXCR3 Surface Expression and Function in CD8+ T Cells from Cutaneous T Cell Lymphoma Patients1
Dorian Winter; Julia Moser; Ernst Kriehuber; Christoph Wiesner; Robert Knobler; Franz Trautinger; Paula Bombosi; Georg Stingl; Peter Petzelbauer; Antal Rot; Dieter Maurer
J Immunol (2007) 179 (6): 4272–4282.
A Biochemical Signature for Rapid Recall of Memory CD4 T Cells1
J Immunol (2007) 179 (6): 3689–3698.
T Cell Lineage Determination Precedes the Initiation of TCRβ Gene Rearrangement1
Kyoko Masuda; Kiyokazu Kakugawa; Toshinori Nakayama; Nagahiro Minato; Yoshimoto Katsura; Hiroshi Kawamoto
J Immunol (2007) 179 (6): 3699–3706.
Involvement of Phosphatidylinositol 3-Kinase-Mediated Up-Regulation of IκBα in Anti-Inflammatory Effect of Gemfibrozil in Microglia1
J Immunol (2007) 179 (6): 4142–4152.
IFN-γ and R-848 Dependent Activation of Human Monocyte-Derived Dendritic Cells by Neisseria meningitidis Adhesin A1
Cristina Mazzon; Barbara Baldani-Guerra; Paola Cecchini; Tihana Kasic; Antonella Viola; Marina de Bernard; Beatrice Aricò; Franca Gerosa; Emanuele Papini
J Immunol (2007) 179 (6): 3904–3916.
Identification of a Second Group of Type I IFNs in Fish Sheds Light on IFN Evolution in Vertebrates1
J Immunol (2007) 179 (6): 3859–3871.
Bruton’s Tyrosine Kinase Mediates NF-κB Activation and B Cell Survival by B Cell-Activating Factor Receptor of the TNF-R Family1
Nicholas P. Shinners; Gianluca Carlesso; Iris Castro; Kristen L. Hoek; Radiah A. Corn; Robert L. Woodland; Martin L. Scott; Demin Wang; Wasif N. Khan
J Immunol (2007) 179 (6): 3872–3880.
Invariant NKT Cells Biased for IL-5 Production Act as Crucial Regulators of Inflammation1
J Immunol (2007) 179 (6): 3452–3462.
Zap70 Signaling Pathway Mediates Glucocorticoid Receptor-Dependent Transcriptional Activation: Role in the Regulation of Annexin 1 Expression in T Cells1
Mohammad Ishaq; Gerald DeGray; Kathy Mou; Angelica Aguilera; Jun Yang; Richard A. Lempicki; Allison Hazen; Ven Natarajan
J Immunol (2007) 179 (6): 3851–3858.
Intracellular Cysteine Residues in the Tail of MHC Class I Proteins Are Crucial for Extracellular Recognition by Leukocyte Ig-Like Receptor 11
Raizy Gruda; Hagit Achdout; Noam Stern-Ginossar; Roi Gazit; Gili Betser-Cohen; Irit Manaster; Gil Katz; Tsufit Gonen-Gross; Boaz Tirosh; Ofer Mandelboim
J Immunol (2007) 179 (6): 3655–3661.
Molecular Determinants of Inverse Agonist Activity of Biologicals Targeting CTLA-41
J Immunol (2007) 179 (6): 3631–3637.
Adhesion and Degranulation-Promoting Adapter Protein (ADAP) Positively Regulates T Cell Sensitivity to Antigen and T Cell Survival1
J Immunol (2007) 179 (6): 3559–3569.
CD8+ T Cell Protective Immunity against Chlamydia pneumoniae Includes an H2-M3-Restricted Response That Is Largely CD4+ T Cell-Independent1
J Immunol (2007) 179 (6): 3947–3957.
In Vitro Induction of Mucosa-Type Dendritic Cells by All-Trans Retinoic Acid1
J Immunol (2007) 179 (6): 3504–3514.
Plasmid-Deficient Chlamydia muridarum Fail to Induce Immune Pathology and Protect against Oviduct Disease1
J Immunol (2007) 179 (6): 4027–4034.
IFN Regulatory Factor Family Members Differentially Regulate the Expression of Type III IFN (IFN-λ) Genes1
J Immunol (2007) 179 (6): 3434–3442.
Chloride Movements in Human Neutrophils during Phagocytosis: Characterization and Relationship to Granule Release
J Immunol (2007) 179 (6): 4110–4124.
Cutting Edge: A Critical Role of Nitrogen Oxide in Preventing Inflammation upon Apoptotic Cell Clearance1
J Immunol (2007) 179 (6): 3407–3411.
Xenogeneic β2-Microglobulin Substitution Affects Functional Binding of MHC Class I Molecules by CD8+ T Cells1
J Immunol (2007) 179 (6): 3588–3595.
Negative Regulation of TLR-Signaling Pathways by Activating Transcription Factor-31
Mark M. Whitmore; Amaya Iparraguirre; Lindsey Kubelka; Wolfgang Weninger; Tsonwin Hai; Bryan R. G. Williams
J Immunol (2007) 179 (6): 3622–3630.
Hydrogen Sulfide Up-Regulates Substance P in Polymicrobial Sepsis-Associated Lung Injury1
J Immunol (2007) 179 (6): 4153–4160.
Dendritic Cell Expression of OX40 Ligand Acts as a Costimulatory, Not Polarizing, Signal for Optimal Th2 Priming and Memory Induction In Vivo1
J Immunol (2007) 179 (6): 3515–3523.
Dendritic Cell Type Determines the Mechanism of Bystander Suppression by Adaptive T Regulatory Cells Specific for the Minor Antigen HA-11
J Immunol (2007) 179 (6): 3443–3451.
Bim and Bcl-2 Mutually Affect the Expression of the Other in T Cells1
Trine N. Jorgensen; Amy McKee; Michael Wang; Ella Kushnir; Janice White; Yosef Refaeli; John W. Kappler; Philippa Marrack
J Immunol (2007) 179 (6): 3417–3424.
Neutrophils Activate Macrophages for Intracellular Killing of Leishmania major through Recruitment of TLR4 by Neutrophil Elastase1
Flavia L. Ribeiro-Gomes; Maria Carolina A. Moniz-de-Souza; Magna S. Alexandre-Moreira; Wagner B. Dias; Marcela F. Lopes; Marise P. Nunes; Giuseppe Lungarella; George A. DosReis
J Immunol (2007) 179 (6): 3988–3994.
Kinetic, Affinity, and Diversity Limits of Human Polyclonal Antibody Responses against Tetanus Toxoid
J Immunol (2007) 179 (6): 3841–3850.
Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages1
Kate Schroder; Martina Spille; Andreas Pilz; Jane Lattin; Konrad A. Bode; Katharine M. Irvine; Allan D. Burrows; Timothy Ravasi; Heike Weighardt; Katryn J. Stacey; Thomas Decker; David A. Hume; Alexander H. Dalpke; Matthew J. Sweet
J Immunol (2007) 179 (6): 3495–3503.
Massive Load of Functional Effector CD4+ and CD8+ T Cells against Cytomegalovirus in Very Old Subjects1
Rosanna Vescovini; Claudia Biasini; Francesco F. Fagnoni; Anna Rita Telera; Luca Zanlari; Mario Pedrazzoni; Laura Bucci; Daniela Monti; Maria Cristina Medici; Carlo Chezzi; Claudio Franceschi; Paolo Sansoni
J Immunol (2007) 179 (6): 4283–4291.
Blockade of Hyaluronan Inhibits IL-2-Induced Vascular Leak Syndrome and Maintains Effectiveness of IL-2 Treatment for Metastatic Melanoma1
J Immunol (2007) 179 (6): 3715–3723.
Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling1
Marit E. Hystad; June H. Myklebust; Trond H. Bø; Einar A. Sivertsen; Edith Rian; Lise Forfang; Else Munthe; Andreas Rosenwald; Michael Chiorazzi; Inge Jonassen; Louis M. Staudt; Erlend B. Smeland
J Immunol (2007) 179 (6): 3662–3671.
The Function of Donor versus Recipient Programmed Death-Ligand 1 in Corneal Allograft Survival1
J Immunol (2007) 179 (6): 3672–3679.
Pathogenic Complement Activation in Collagen Antibody- Induced Arthritis in Mice Requires Amplification by the Alternative Pathway1
J Immunol (2007) 179 (6): 4101–4109.
Cytoplasmic Linker Protein-170 Enhances Spreading and Phagocytosis in Activated Macrophages by Stabilizing Microtubules1
J Immunol (2007) 179 (6): 3780–3791.
The Endothelial Cell-Produced Antiangiogenic Cytokine Vascular Endothelial Growth Inhibitor Induces Dendritic Cell Maturation1
J Immunol (2007) 179 (6): 3742–3751.
CD45RB Ligation Inhibits Allergic Pulmonary Inflammation by Inducing CTLA4 Transcription1
Kai Yu Jen; Monica Campo; Hongzhen He; Samir S. Makani; German Velasco; David M. Rothstein; David L. Perkins; Patricia W. Finn
J Immunol (2007) 179 (6): 4212–4218.
Functional Transient Receptor Potential Melastatin 7 Channels Are Critical for Human Mast Cell Survival
J Immunol (2007) 179 (6): 4045–4052.
Variant IL-1 Receptor-Associated Kinase-1 Mediates Increased NF-κB Activity1
J Immunol (2007) 179 (6): 4125–4134.
Histamine Improves Antigen Uptake and Cross-Presentation by Dendritic Cells1
Maria Marta Amaral; Carlos Davio; Ana Ceballos; Gabriela Salamone; Cristian Cañones; Jorge Geffner; Mónica Vermeulen
J Immunol (2007) 179 (6): 3425–3433.
Reduction of Bleomycin-Induced Pulmonary Fibrosis by Serum Amyloid P1
Darrell Pilling; David Roife; Min Wang; Sanna D. Ronkainen; Jeff R. Crawford; Elizabeth L. Travis; Richard H. Gomer
J Immunol (2007) 179 (6): 4035–4044.
DAP10 Deficiency Breaks the Immune Tolerance against Transplantable Syngeneic Melanoma1
J Immunol (2007) 179 (6): 3763–3771.
Chemoattraction of Macrophages, T Lymphocytes, and Mast Cells Is Evolutionarily Conserved within the Human α-Defensin Family1
J Immunol (2007) 179 (6): 3958–3965.
Kaempferol Inhibits IL-4-Induced STAT6 Activation by Specifically Targeting JAK31
J Immunol (2007) 179 (6): 3881–3887.
Cutting Edge: Selective Tyrosine Dephosphorylation of Interferon-Activated Nuclear STAT5 by the VHR Phosphatase1
J Immunol (2007) 179 (6): 3402–3406.
Cutting Edge: Syntaxin 11 Regulates Lymphocyte-Mediated Secretion and Cytotoxicity1
Laura N. Arneson; Adipong Brickshawana; Colin M. Segovis; Renee A. Schoon; Christopher J. Dick; Paul J. Leibson
J Immunol (2007) 179 (6): 3397–3401.
Granzyme B Activity in Target Cells Detects Attack by Cytotoxic Lymphocytes
J Immunol (2007) 179 (6): 3812–3820.
Impaired Induction of CD27 and CD28 Predicts Naive CD4 T Cell Proliferation Defects in HIV Disease1
J Immunol (2007) 179 (6): 3543–3549.
Bcl10 Plays a Divergent Role in NK Cell-Mediated Cytotoxicity and Cytokine Generation1
Subramaniam Malarkannan; Jeyarani Regunathan; Haiyan Chu; Snjezana Kutlesa; Yuhong Chen; Hu Zeng; Renren Wen; Demin Wang
J Immunol (2007) 179 (6): 3752–3762.
Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells1
J Immunol (2007) 179 (6): 3724–3733.
A Key Role for TGF-β Signaling to T Cells in the Long-Term Acceptance of Allografts1
J Immunol (2007) 179 (6): 3648–3654.
The B7 Homolog Butyrophilin BTN2A1 Is a Novel Ligand for DC-SIGN1
J Immunol (2007) 179 (6): 3804–3811.
Systemic Tumor Necrosis Factor Generated during Lethal Plasmodium Infections Impairs Dendritic Cell Function1
J Immunol (2007) 179 (6): 3982–3987.
Increased Transcriptional Activity of Milk-Related Genes following the Active Phase of Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis1
David Otaegui; Sara Mostafavi; Claude C. A. Bernard; Adolfo Lopez de Munain; Parvin Mousavi; Jorge R. Oksenberg; Sergio E. Baranzini
J Immunol (2007) 179 (6): 4074–4082.
Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection1
Maziar Divangahi; Tony Yang; Kapilan Kugathasan; Sarah McCormick; Shunsuke Takenaka; Gordon Gaschler; Ali Ashkar; Martin Stampfli; Jack Gauldie; Jonathan Bramson; Toshiyuki Takai; Earl Brown; Wayne M. Yokoyama; Naoko Aoki; Zhou Xing
J Immunol (2007) 179 (6): 4015–4026.
Mouse Neutrophils Require JNK2 MAPK for Toxoplasma gondii-Induced IL-12p40 and CCL2/MCP-1 Release1
J Immunol (2007) 179 (6): 3570–3577.
Function and Regulation of SPLUNC1 Protein in Mycoplasma Infection and Allergic Inflammation1
Hong Wei Chu; Jyoti Thaikoottathil; John G. Rino; Gongyi Zhang; Qun Wu; Taylor Moss; Yosef Refaeli; Russell Bowler; Sally E. Wenzel; Zhongzhou Chen; Jeffrey Zdunek; Rachel Breed; Ryan Young; Erin Allaire; Richard J. Martin
J Immunol (2007) 179 (6): 3995–4002.
Enhanced Levels of Costimulation Lead to Reduced Effector/Memory CD8+ T Cell Functionality1
J Immunol (2007) 179 (6): 3524–3534.
TLR9 Is Required for Protective Innate Immunity in Gram-Negative Bacterial Pneumonia: Role of Dendritic Cells
Urvashi Bhan; Nicholas W. Lukacs; John J. Osterholzer; Michael W. Newstead; Xianying Zeng; Thomas A. Moore; Tracy R. McMillan; Arthur M. Krieg; Shizuo Akira; Theodore J. Standiford
J Immunol (2007) 179 (6): 3937–3946.
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Cover Image
Cover Image
![issue cover]()
On the cover: Adoptive transfer of OVA-specific T cells (red), capable of expressing IL-4 (green), into IL-4-/- mice inoculated with N. brasiliensis plus OVA. Frozen draining lymph node sections from day 3 after inoculation were also stained for B cells (blue) to indicate T:B zone, where IL-4 protein is initially expressed. Liu, Q., Z. Liu, C. T. Rozo, H. A. Hamed, F. Alem, J. F. Urban, Jr., and W. C. Gause. 2007. The role of B cells in the development of CD4 effector T cells during a polarized Th2 immune response. J. Immunol. 179: 3821–3830.
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