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Issues
1 October 2007
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
The Peptide Cargo of Class I Molecules: Not Just Passive Passengers
J Immunol (2007) 179 (7): 4299–4300.
Pillars Article: Association of Class I Major Histocompatibility Heavy and Light Chains Induced by Viral Peptides. Nature 1989. 340: 443–448.
J Immunol (2007) 179 (7): 4301–4306.
BRIEF REVIEWS
A New Class of Reverse Signaling Costimulators Belongs to the TNF Family
J Immunol (2007) 179 (7): 4307–4312.
CUTTING EDGE
Cutting Edge: An In Vivo Requirement for STAT3 Signaling in TH17 Development and TH17-Dependent Autoimmunity1
Timothy J. Harris; Joseph F. Grosso; Hung-Rong Yen; Hong Xin; Marcin Kortylewski; Emilia Albesiano; Edward L. Hipkiss; Derese Getnet; Monica V. Goldberg; Charles H. Maris; Franck Housseau; Hua Yu; Drew M. Pardoll; Charles G. Drake
J Immunol (2007) 179 (7): 4313–4317.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
CD8+CD28− T Regulatory Lymphocytes Inhibiting T Cell Proliferative and Cytotoxic Functions Infiltrate Human Cancers1
Gilberto Filaci; Daniela Fenoglio; Marco Fravega; Gianluca Ansaldo; Giacomo Borgonovo; Paolo Traverso; Barbara Villaggio; Alessandra Ferrera; Annalisa Kunkl; Marta Rizzi; Francesca Ferrera; Piercesare Balestra; Massimo Ghio; Paola Contini; Maurizio Setti; Daniel Olive; Bruno Azzarone; Giorgio Carmignani; Jean Louis Ravetti; Giancarlo Torre; Francesco Indiveri
J Immunol (2007) 179 (7): 4323–4334.
Natural Phosphorylation of CD5 in Chronic Lymphocytic Leukemia B Cells and Analysis of CD5-Regulated Genes in a B Cell Line Suggest a Role for CD5 in Malignant Phenotype1
Hélène Gary-Gouy; Alexander Sainz-Perez; Jean-Brice Marteau; Anne Marfaing-Koka; Jozo Delic; Hélène Merle-Beral; Pierre Galanaud; Ali Dalloul
J Immunol (2007) 179 (7): 4335–4344.
Copolymer-1 Induces Adaptive Immune Anti-inflammatory Glial and Neuroprotective Responses in a Murine Model of HIV-1 Encephalitis1
Santhi Gorantla; Jianou Liu; Hannah Sneller; Huanyu Dou; Adelina Holguin; Lynette Smith; Tsuneya Ikezu; David J. Volsky; Larisa Poluektova; Howard E. Gendelman
J Immunol (2007) 179 (7): 4345–4356.
Serine Protease Inhibitor 6-Deficient Mice Have Increased Neutrophil Immunity to Pseudomonas aeruginosa1
Manling Zhang; Ni Liu; Sun-Mi Park; Yue Wang; Susan Byrne; Andrea E. Murmann; Scott Bahr; Marcus E. Peter; Steven T. Olson; Abderrazzaq Belaaouaj; Philip G. Ashton-Rickardt
J Immunol (2007) 179 (7): 4390–4396.
Inhibition of Terminal Complement Components in Presensitized Transplant Recipients Prevents Antibody-Mediated Rejection Leading to Long-Term Graft Survival and Accommodation1
Hao Wang; Jacqueline Arp; Weihua Liu; Susan J. Faas; Jifu Jiang; David R. Gies; Siobhan Ramcharran; Bertha Garcia; Robert Zhong; Russell P. Rother
J Immunol (2007) 179 (7): 4451–4463.
The CD16−CD56bright NK Cell Subset Is Resistant to Reactive Oxygen Species Produced by Activated Granulocytes and Has Higher Antioxidative Capacity Than the CD16+CD56dim Subset1
Helena Harlin; Mikael Hanson; C. Christian Johansson; Daiju Sakurai; Isabel Poschke; Håkan Norell; Karl-Johan Malmberg; Rolf Kiessling
J Immunol (2007) 179 (7): 4513–4519.
Calcineurin Negatively Regulates TLR-Mediated Activation Pathways1
Young Jun Kang; Brenda Kusler; Motoyuki Otsuka; Michael Hughes; Nobutaka Suzuki; Shinobu Suzuki; Wen-Chen Yeh; Shizuo Akira; Jiahuai Han; Patricia P. Jones
J Immunol (2007) 179 (7): 4598–4607.
All-trans Retinoic Acid Enhances Murine Dendritic Cell Migration to Draining Lymph Nodes via the Balance of Matrix Metalloproteinases and Their Inhibitors1
Stephanie Darmanin; Jian Chen; Songji Zhao; Hongyan Cui; Reza Shirkoohi; Naoki Kubo; Yuji Kuge; Nagara Tamaki; Koji Nakagawa; Jun-ichi Hamada; Tetsuya Moriuchi; Masanobu Kobayashi
J Immunol (2007) 179 (7): 4616–4625.
iNKT Cells Require CCR4 to Localize to the Airways and to Induce Airway Hyperreactivity1
Everett H. Meyer; Marc-André Wurbel; Tracy L. Staton; Muriel Pichavant; Matthew J. Kan; Paul B. Savage; Rosemarie H. DeKruyff; Eugene C. Butcher; James J. Campbell; Dale T. Umetsu
J Immunol (2007) 179 (7): 4661–4671.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
IMMUNOGENETICS
HOST DEFENSE
Alternatively Activated Macrophages in Intestinal Helminth Infection: Effects on Concurrent Bacterial Colitis1
Meiqian Weng; Deke Huntley; I-Fei Huang; Ondulla Foye-Jackson; Lijian Wang; Aliese Sarkissian; Qingping Zhou; W. Allan Walker; Bobby J. Cherayil; Hai Ning Shi
J Immunol (2007) 179 (7): 4721–4731.
Live Attenuated Lentivirus Infection Elicits Polyfunctional Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells with Reduced Apoptotic Susceptibility in Rhesus Macaques that Control Virus Replication after Challenge with Pathogenic SIVmac2391
Meritxell Genescà; Tracy Rourke; Jun Li; Kristen Bost; Barinderpaul Chohan; Michael B. McChesney; Christopher J. Miller
J Immunol (2007) 179 (7): 4732–4740.
In Vivo Electroporation Enhances the Immunogenicity of Hepatitis C Virus Nonstructural 3/4A DNA by Increased Local DNA Uptake, Protein Expression, Inflammation, and Infiltration of CD3+ T Cells1
Gustaf Ahlén; Jonas Söderholm; Torunn Tjelle; Rune Kjeken; Lars Frelin; Urban Höglund; Pontus Blomberg; Michael Fons; Iacob Mathiesen; Matti Sällberg
J Immunol (2007) 179 (7): 4741–4753.
TLR9 Activation Induces Normal Neutrophil Responses in a Child with IRAK-4 Deficiency: Involvement of the Direct PI3K Pathway
Cyrille Hoarau; Bénédicte Gérard; Emmanuel Lescanne; Dominique Henry; Stéphanie François; Jean-Jacques Lacapère; Jamel El Benna; Pham My-Chan Dang; Bernard Grandchamp; Yvon Lebranchu; Marie-Anne Gougerot-Pocidalo; Carole Elbim
J Immunol (2007) 179 (7): 4754–4765.
INFLAMMATION
Deletion of Secretory Group V Phospholipase A2 Attenuates Cell Migration and Airway Hyperresponsiveness in Immunosensitized Mice1
J Immunol (2007) 179 (7): 4800–4807.
A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair1
Cynthia L. Leaphart; Jaime Cavallo; Steven C. Gribar; Selma Cetin; Jun Li; Maria F. Branca; Theresa D. Dubowski; Chhinder P. Sodhi; David J. Hackam
J Immunol (2007) 179 (7): 4808–4820.
Deficiency of the NF-κB Inhibitor Caspase Activating and Recruitment Domain 8 in Patients with Rheumatoid Arthritis Is Associated with Disease Severity1
Ana Fontalba; Victor Martinez-Taboada; Olga Gutierrez; Carlos Pipaon; Natividad Benito; Alejandro Balsa; Ricardo Blanco; Jose L. Fernandez-Luna
J Immunol (2007) 179 (7): 4867–4873.
CLINICAL IMMUNOLOGY
Synergistic Induction of Antigen-Specific CTL by Fusions of TLR-Stimulated Dendritic Cells and Heat-Stressed Tumor Cells1
Shigeo Koido; Eiichi Hara; Sadamu Homma; Makoto Mitsunaga; Akitaka Takahara; Eijiro Nagasaki; Hidejiro Kawahara; Michiaki Watanabe; Yoichi Toyama; Satoru Yanagisawa; Susumu Kobayashi; Katsuhiko Yanaga; Kiyotaka Fujise; Jianlin Gong; Hisao Tajiri
J Immunol (2007) 179 (7): 4874–4883.
Defective Expression of Ras Guanyl Nucleotide-Releasing Protein 1 in a Subset of Patients with Systemic Lupus Erythematosus1
Shinsuke Yasuda; Richard L. Stevens; Tomoko Terada; Masumi Takeda; Toko Hashimoto; Jun Fukae; Tetsuya Horita; Hiroshi Kataoka; Tatsuya Atsumi; Takao Koike
J Immunol (2007) 179 (7): 4890–4900.
Achieving Donor-Specific Hyporesponsiveness Is Associated with FOXP3+ Regulatory T Cell Recruitment in Human Renal Allograft Infiltrates1
Oriol Bestard; Josep M. Cruzado; Mariona Mestre; Anna Caldés; Jordi Bas; Marta Carrera; Joan Torras; Inés Rama; Francesc Moreso; Daniel Serón; Josep M. Grinyó
J Immunol (2007) 179 (7): 4901–4909.
Administration of a CD25-Directed Immunotoxin, LMB-2, to Patients with Metastatic Melanoma Induces a Selective Partial Reduction in Regulatory T Cells In Vivo1
Daniel J. Powell, Jr.; Aloisio Felipe-Silva; Maria J. Merino; Mojgan Ahmadzadeh; Tamika Allen; Catherine Levy; Donald E. White; Sharon Mavroukakis; Robert J. Kreitman; Steven A. Rosenberg; Ira Pastan
J Immunol (2007) 179 (7): 4919–4928.
Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome1
Michele Bombardieri; Francesca Barone; Frances Humby; Stephen Kelly; Mark McGurk; Peter Morgan; Stephen Challacombe; Salvatore De Vita; Guido Valesini; Jo Spencer; Costantino Pitzalis
J Immunol (2007) 179 (7): 4929–4938.
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Cover Image
Cover Image
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On the cover: 40x H&E stain of paraformaldehyde-fixed and paraffin-embedded human skin grafted onto C.B-17 SCID/beige mice that had been adoptively transferred with human effector memory CD4+ T cells (CD45RO+CCR7-CD62L-) and harvested after 3 wk. The dermis shows signs of significant rejection including extensive infiltration of leukocytes and thrombosis of the microvasculature. Shiao, S. L., N. C. Kirkiles-Smith, B. R. Shepherd, J. M. McNiff, E. J. Carr, and J. S. Pober. 2007. Human effector memory CD4+ T cells directly recognize allogeneic endothelial cells in vitro and in vivo. J. Immunol. 179: 4397–4404.
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