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15 October 2007
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
CUTTING EDGE
Cutting Edge: IL-4-Mediated Protection of Primary B Lymphocytes from Apoptosis via Stat6-Dependent Regulation of Glycolytic Metabolism1
Fay J. Dufort; Blair F. Bleiman; Maria R. Gumina; Derek Blair; Dean J. Wagner; Mary F. Roberts; Yousef Abu-Amer; Thomas C. Chiles
J Immunol (2007) 179 (8): 4953–4957.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors1
Anja U. van Lent; Maho Nagasawa; Marleen M. van Loenen; Remko Schotte; Ton N. M. Schumacher; Mirjam H. M. Heemskerk; Hergen Spits; Nicolas Legrand
J Immunol (2007) 179 (8): 4959–4968.
The Role of Apoptosis in the Ameliorating Effects of a CDR1-Based Peptide on Lupus Manifestations in a Mouse Model1
J Immunol (2007) 179 (8): 4979–4987.
The Surprising Kinetics of the T Cell Response to Live Antigenic Cells1
J Immunol (2007) 179 (8): 4988–4995.
Maintenance of Surrogate Light Chain Expression Induces Developmental Delay in Early B Cell Compartment1
J Immunol (2007) 179 (8): 4996–5005.
Discriminating between Different Pathways of Memory CD8+ T Cell Differentiation1
J Immunol (2007) 179 (8): 5006–5013.
Differential Requirements for OX40 Signals on Generation of Effector and Central Memory CD4+ T Cells1
J Immunol (2007) 179 (8): 5014–5023.
Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL1
Lea Luketic; Jordan Delanghe; Paul T. Sobol; Pingchang Yang; Erin Frotten; Karen L. Mossman; Jack Gauldie; Jonathan Bramson; Yonghong Wan
J Immunol (2007) 179 (8): 5024–5032.
CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund’s Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity1
Martijn S. Bijker; Susan J. F. van den Eeden; Kees L. Franken; Cornelis J. M. Melief; Rienk Offringa; Sjoerd H. van der Burg
J Immunol (2007) 179 (8): 5033–5040.
The Countervailing Actions of Myeloid and Plasmacytoid Dendritic Cells Control Autoimmune Diabetes in the Nonobese Diabetic Mouse1
J Immunol (2007) 179 (8): 5041–5053.
The α1β1 Integrin and TNF Receptor II Protect Airway CD8+ Effector T Cells from Apoptosis during Influenza Infection1
J Immunol (2007) 179 (8): 5054–5063.
PD-1 Regulates Self-Reactive CD8+ T Cell Responses to Antigen in Lymph Nodes and Tissues1
J Immunol (2007) 179 (8): 5064–5070.
Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock1
Esmerina Tili; Jean-Jacques Michaille; Amelia Cimino; Stefan Costinean; Calin Dan Dumitru; Brett Adair; Muller Fabbri; Hannes Alder; Chang Gong Liu; George Adrian Calin; Carlo Maria Croce
J Immunol (2007) 179 (8): 5082–5089.
CD8 T Cell Responses to Myelin Oligodendrocyte Glycoprotein-Derived Peptides in Humanized HLA-A*0201-Transgenic Mice1
Lennart T. Mars; Jan Bauer; David A. Gross; Florence Bucciarelli; Huseyin Firat; Denis Hudrisier; François Lemonnier; Kostas Kosmatopoulos; Roland S. Liblau
J Immunol (2007) 179 (8): 5090–5098.
Expression of CD80/86 on B Cells Is Essential for Autoreactive T Cell Activation and the Development of Arthritis1
J Immunol (2007) 179 (8): 5109–5116.
Unique Features and Distribution of the Chicken CD83+ Cell1
Chris Hansell; Xing Wu Zhu; Heather Brooks; Mark Sheppard; Sam Withanage; Duncan Maskell; Ian McConnell
J Immunol (2007) 179 (8): 5117–5125.
Hydrodynamic Vaccination with DNA Encoding an Immunologically Privileged Retinal Antigen Protects from Autoimmunity through Induction of Regulatory T Cells1
Phyllis B. Silver; Rajeev K. Agarwal; Shao-Bo Su; Isabelle Suffia; Rafael S. Grajewski; Dror Luger; Chi-Chao Chan; Rashid M. Mahdi; John M. Nickerson; Rachel R. Caspi
J Immunol (2007) 179 (8): 5146–5158.
Inhibition of T Cell Activation by Cyclic Adenosine 5′-Monophosphate Requires Lipid Raft Targeting of Protein Kinase A Type I by the A-Kinase Anchoring Protein Ezrin1
Anja Ruppelt; Randi Mosenden; Mikaela Grönholm; Einar M. Aandahl; Derek Tobin; Cathrine R. Carlson; Hilde Abrahamsen; Friedrich W. Herberg; Olli Carpén; Kjetil Taskén
J Immunol (2007) 179 (8): 5159–5168.
PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft Rejection1
Katsunori Tanaka; Monica J. Albin; Xueli Yuan; Kazuhiro Yamaura; Antje Habicht; Takaya Murayama; Martin Grimm; Ana Maria Waaga; Takuya Ueno; Robert F. Padera; Hideo Yagita; Miyuki Azuma; Tahiro Shin; Bruce R. Blazar; David M. Rothstein; Mohamed H. Sayegh; Nader Najafian
J Immunol (2007) 179 (8): 5204–5210.
A Link between PDL1 and T Regulatory Cells in Fetomaternal Tolerance1
Antje Habicht; Shirine Dada; Mollie Jurewicz; Brian T. Fife; Hideo Yagita; Miyuki Azuma; Mohamed H. Sayegh; Indira Guleria
J Immunol (2007) 179 (8): 5211–5219.
High Susceptibility of Human Dendritic Cells to Avian Influenza H5N1 Virus Infection and Protection by IFN-α and TLR Ligands1
Arunee Thitithanyanont; Anneke Engering; Peeraya Ekchariyawat; Suwimon Wiboon-ut; Amporn Limsalakpetch; Kosol Yongvanitchit; Utaiwan Kum-Arb; Watcharoot Kanchongkittiphon; Pongsak Utaisincharoen; Stitaya Sirisinha; Pilaipan Puthavathana; Mark M. Fukuda; Sathit Pichyangkul
J Immunol (2007) 179 (8): 5220–5227.
CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis1
Bing Zhu; Yoshio Bando; Sheng Xiao; Kaiyong Yang; Ana C. Anderson; Vijay K. Kuchroo; Samia J. Khoury
J Immunol (2007) 179 (8): 5228–5237.
Antibody-Mediated Rejection of Cardiac Allografts in CCR5-Deficient Recipients1
Taiji Nozaki; Hiroyuki Amano; Alice Bickerstaff; Charles G. Orosz; Andrew C. Novick; Kazunari Tanabe; Robert L. Fairchild
J Immunol (2007) 179 (8): 5238–5245.
Induction of Indoleamine 2,3-Dioxygenase in Vascular Smooth Muscle Cells by Interferon-γ Contributes to Medial Immunoprivilege1
Madison C. Cuffy; Amanda M. Silverio; Lingfeng Qin; Yinong Wang; Raymond Eid; Gerald Brandacher; Fadi G. Lakkis; Dietmar Fuchs; Jordan S. Pober; George Tellides
J Immunol (2007) 179 (8): 5246–5254.
All-or-None Activation of CRAC Channels by Agonist Elicits Graded Responses in Populations of Mast Cells1
J Immunol (2007) 179 (8): 5255–5263.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Dynamic Changes in Accessibility, Nuclear Positioning, Recombination, and Transcription at the Igκ Locus12
J Immunol (2007) 179 (8): 5264–5273.
Role of Activation-Induced Deaminase Protein Kinase A Phosphorylation Sites in Ig Gene Conversion and Somatic Hypermutation1
J Immunol (2007) 179 (8): 5274–5280.
Protein Kinase C Regulates Expression and Function of Inhibitory Killer Cell Ig-Like Receptors in NK Cells1
J Immunol (2007) 179 (8): 5281–5290.
A Fas-Associated Death Domain Protein/Caspase-8-Signaling Axis Promotes S-Phase Entry and Maintains S6 Kinase Activity in T Cells Responding to IL-21
Adrian F. Arechiga; Bryan D. Bell; Sabrina Leverrier; Brian M. Weist; Melissa Porter; Zhengqi Wu; Yuka Kanno; Stephanie J. Ramos; S. Tiong Ong; Richard Siegel; Craig M. Walsh
J Immunol (2007) 179 (8): 5291–5300.
STAT5 Is Essential for Akt/p70S6 Kinase Activity during IL-2-Induced Lymphocyte Proliferation1
J Immunol (2007) 179 (8): 5301–5308.
Analysis of Epitope-Specific Immune Responses Induced by Vaccination with Structurally Folded and Unfolded Recombinant Bet v 1 Allergen Derivatives in Man1
Ines Pree; Jürgen Reisinger; Margit Focke; Susanne Vrtala; Gabrielle Pauli; Marianne van Hage; Oliver Cromwell; Elisabeth Gadermaier; Cornelia Egger; Norbert Reider; Friedrich Horak; Rudolf Valenta; Verena Niederberger
J Immunol (2007) 179 (8): 5309–5316.
A Role for EZH2 in Silencing of IFN-γ Inducible MHC2TA Transcription in Uveal Melanoma1
Tjadine M. Holling; Marloes W. T. Bergevoet; Louis Wilson; Marja C. J. A. Van Eggermond; Erik Schooten; Renske D. M. Steenbergen; Peter J. F. Snijders; Martine J. Jager; Peter J. Van den Elsen
J Immunol (2007) 179 (8): 5317–5325.
IMMUNOGENETICS
Expression Profiling of Immature Thymocytes Revealed a Novel Homeobox Gene That Regulates Double-Negative Thymocyte Development1
Masahito Kawazu; Go Yamamoto; Mayumi Yoshimi; Kazuki Yamamoto; Takashi Asai; Motoshi Ichikawa; Sachiko Seo; Masahiro Nakagawa; Shigeru Chiba; Mineo Kurokawa; Seishi Ogawa
J Immunol (2007) 179 (8): 5335–5345.
HOST DEFENSE
The Acquired Immune Response to the Mucosal Adjuvant LTK63 Imprints the Mouse Lung with a Protective Signature
Elaine Tritto; Alessandro Muzzi; Isabella Pesce; Elisabetta Monaci; Sandra Nuti; Grazia Galli; Andreas Wack; Rino Rappuoli; Tracy Hussell; Ennio De Gregorio
J Immunol (2007) 179 (8): 5346–5357.
Lymphotoxin αβ2 (Membrane Lymphotoxin) Is Critically Important for Resistance to Leishmania major Infection in Mice1
J Immunol (2007) 179 (8): 5358–5366.
IL-13 Induces Disease-Promoting Type 2 Cytokines, Alternatively Activated Macrophages and Allergic Inflammation during Pulmonary Infection of Mice with Cryptococcus neoformans1
Uwe Müller; Werner Stenzel; Gabriele Köhler; Christoph Werner; Tobias Polte; Gesine Hansen; Nicole Schütze; Reinhard K. Straubinger; Manfred Blessing; Andrew N. J. McKenzie; Frank Brombacher; Gottfried Alber
J Immunol (2007) 179 (8): 5367–5377.
The C/EBPβ Isoform 34-kDa LAP Is Responsible for NF-IL-6-Mediated Gene Induction in Activated Macrophages, but Is Not Essential for Intracellular Bacteria Killing1
Satoshi Uematsu; Tsuneyasu Kaisho; Takashi Tanaka; Makoto Matsumoto; Megumi Yamakami; Hiroko Omori; Masahiro Yamamoto; Tamotsu Yoshimori; Shizuo Akira
J Immunol (2007) 179 (8): 5378–5386.
Bone Marrow of Persistently Hepatitis C Virus-Infected Individuals Accumulates Memory CD8+ T Cells Specific for Current and Historical Viral Antigens: A Study in Patients with Benign Hematological Disorders1
Vito Racanelli; Maria Antonia Frassanito; Patrizia Leone; Claudia Brunetti; Simona Ruggieri; Franco Dammacco
J Immunol (2007) 179 (8): 5387–5398.
The Proinflammatory Cytokine Macrophage Migration Inhibitory Factor Regulates Glucose Metabolism during Systemic Inflammation1
Toshiya Atsumi; You-Ree Cho; Lin Leng; Courtney McDonald; Tim Yu; Cheryl Danton; Eun-Gyoung Hong; Robert A. Mitchell; Christine Metz; Hirokatsu Niwa; Jun Takeuchi; Shin Onodera; Tomomi Umino; Narihito Yoshioka; Takao Koike; Jason K. Kim; Richard Bucala
J Immunol (2007) 179 (8): 5399–5406.
CD8 T Cells Inhibit Respiratory Syncytial Virus (RSV) Vaccine-Enhanced Disease1
J Immunol (2007) 179 (8): 5415–5424.
Activation of Innate Immune Defense Mechanisms by Signaling through RIG-I/IPS-1 in Intestinal Epithelial Cells1
J Immunol (2007) 179 (8): 5425–5432.
Helicobacter pylori Vacuolating Cytotoxin Inhibits Activation-Induced Proliferation of Human T and B Lymphocyte Subsets1
J Immunol (2007) 179 (8): 5433–5440.
Regulation of Tumor Cell Sensitivity to TRAIL-Induced Apoptosis by the Metastatic Suppressor Raf Kinase Inhibitor Protein via Yin Yang 1 Inhibition and Death Receptor 5 Up-Regulation
Stavroula Baritaki; Alina Katsman; Devasis Chatterjee; Kam C. Yeung; Demetrios A. Spandidos; Benjamin Bonavida
J Immunol (2007) 179 (8): 5441–5453.
INFLAMMATION
Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F
Rolf E. Kuestner; David W. Taft; Aaron Haran; Cameron S. Brandt; Ty Brender; Karen Lum; Brandon Harder; Shannon Okada; Craig D. Ostrander; James L. Kreindler; Shean J. Aujla; Brian Reardon; Margaret Moore; Pamela Shea; Randall Schreckhise; Thomas R. Bukowski; Scott Presnell; Patricia Guerra-Lewis; Julia Parrish-Novak; Jeff L. Ellsworth; Stephen Jaspers; Katherine E. Lewis; Mark Appleby; Jay K. Kolls; Mark Rixon; James W. West; Zeren Gao; Steven D. Levin
J Immunol (2007) 179 (8): 5462–5473.
The Chemokine CCL6 Promotes Innate Immunity via Immune Cell Activation and Recruitment1
Ana L. Coelho; Matthew A. Schaller; Claudia F. Benjamim; Amos Z. Orlofsky; Cory M. Hogaboam; Steven L. Kunkel
J Immunol (2007) 179 (8): 5474–5482.
Adiponectin Enhances IL-6 Production in Human Synovial Fibroblast via an AdipoR1 Receptor, AMPK, p38, and NF-κB Pathway1
J Immunol (2007) 179 (8): 5483–5492.
Proteinase-Activated Receptor-2 Exerts Protective and Pathogenic Cell Type-Specific Effects in Alzheimer’s Disease1
Amir Afkhami-Goli; Farshid Noorbakhsh; Avril J. Keller; Nathalie Vergnolle; David Westaway; Jack H. Jhamandas; Patricia Andrade-Gordon; Morley D. Hollenberg; Hosseinali Arab; Richard H. Dyck; Christopher Power
J Immunol (2007) 179 (8): 5493–5503.
Hepatocyte Growth Factor Significantly Suppresses Collagen-Induced Arthritis in Mice
Katsuhide Okunishi; Makoto Dohi; Keishi Fujio; Kazuyuki Nakagome; Yasuhiko Tabata; Takahiro Okasora; Makoto Seki; Mihoko Shibuya; Mitsuru Imamura; Hiroaki Harada; Ryoichi Tanaka; Kazuhiko Yamamoto
J Immunol (2007) 179 (8): 5504–5513.
The IFN-Inducible GTPase LRG47 (Irgm1) Negatively Regulates TLR4-Triggered Proinflammatory Cytokine Production and Prevents Endotoxemia1
Andre Bafica; Carl G. Feng; Helton C. Santiago; Julio Aliberti; Allen Cheever; Karen E. Thomas; Gregory A. Taylor; Stefanie N. Vogel; Alan Sher
J Immunol (2007) 179 (8): 5514–5522.
CLINICAL IMMUNOLOGY
The Heat Shock Protein HSP70 Promotes Mouse NK Cell Activity against Tumors That Express Inducible NKG2D Ligands1
Leslie Elsner; Vijayakumar Muppala; Mathias Gehrmann; Jingky Lozano; Dörthe Malzahn; Heike Bickeböller; Edgar Brunner; Marta Zientkowska; Thomas Herrmann; Lutz Walter; Frauke Alves; Gabriele Multhoff; Ralf Dressel
J Immunol (2007) 179 (8): 5523–5533.
Dual T Cell Receptor Expressing CD8+ T Cells with Tumor- and Self-Specificity Can Inhibit Tumor Growth without Causing Severe Autoimmunity1
J Immunol (2007) 179 (8): 5534–5542.
Impaired T Cell Protein Kinase Cδ Activation Decreases ERK Pathway Signaling in Idiopathic and Hydralazine-Induced Lupus1
J Immunol (2007) 179 (8): 5553–5563.
Mature B Cells Preferentially Lose Tolerance in the Chronic Graft-versus-Host Disease Model of Systemic Lupus Erythematosus1
J Immunol (2007) 179 (8): 5564–5570.
Intravenous Immunoglobulin Therapy Affects T Regulatory Cells by Increasing Their Suppressive Function
Aharon Kessel; Hana Ammuri; Regina Peri; Elsa R. Pavlotzky; Miri Blank; Yehuda Shoenfeld; Elias Toubi
J Immunol (2007) 179 (8): 5571–5575.
Exacerbation of Collagen-Induced Arthritis by Oligoclonal, IL-17-Producing γδ T Cells1
Christina L. Roark; Jena D. French; Molly A. Taylor; Alison M. Bendele; Willi K. Born; Rebecca L. O’Brien
J Immunol (2007) 179 (8): 5576–5583.
OX40 Controls Functionally Different T Cell Subsets and Their Resistance to Depletion Therapy1
Alexander Kroemer; Xiang Xiao; Minh Diem Vu; Wenda Gao; Keisuke Minamimura; Ming Chen; Takashi Maki; Xian Chang Li
J Immunol (2007) 179 (8): 5584–5591.
IL-10- and TGF-β-Mediated Susceptibility in Kala-azar and Post-kala-azar Dermal Leishmaniasis: The Significance of Amphotericin B in the Control of Leishmania donovani Infection in India1
Samiran Saha; Smriti Mondal; Rajesh Ravindran; Swati Bhowmick; Dolanchampa Modak; Sudeshna Mallick; Mehboobar Rahman; Sourjya Kar; Ramaprasad Goswami; Subhasis Kamal Guha; Netai Pramanik; Bibhuti Saha; Nahid Ali
J Immunol (2007) 179 (8): 5592–5603.
CORRECTIONS
The urokinase/urokinase receptor system mediates the IgG immune complex-induced inflammation in lung.
N. Shushakova; G. Eden; M. Dangers; J. Zwirner; J. Menne; F. Gueler; F. C. Luft; H. Haller; I. Dumler
J Immunol (2007) 179 (8): 5604.
Poly(ADP-ribose) polymerase-1 inhibition prevents eosinophil recruitment by modulating Th2 cytokines in a murine model of allergic airway inflammation: a potential specific effect on IL-5.
O. Mustapha; R. Datta; K. Oumouna-Benachour; Y. Suzuki; C. Hans; K. Matthews; K. Fallon; H. Boulares
J Immunol (2007) 179 (8): 5604.
Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial Ags by MHC molecules.
J Immunol (2007) 179 (8): 5604.
Fusobacterium nucleatum induces fetal death in mice via stimulation of TLR4-mediated placental inflammatory response.
J Immunol (2007) 179 (8): 5604–5605.
CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cells.
I. Fernandez; R. Zeiser; H. Karsunky; N. Kambham; A. Beilhack; K. Soderstrom; R. S. Negrin; E. Engleman
J Immunol (2007) 179 (8): 5605.
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Cover Image
Cover Image
On the cover: Peripheral distribution of CD19highCD45R-/low mature B cells in spleen follicles of BALB/c mice. The merged image of confocal microscopy shows that the majority of cells expressing CD19 (green) but not CD4R/B220 (red) are close to the MOMA-1+ band of metallophilic macrophages (blue) that defines the internal border of the marginal zone (MZ). de Andrès, B., I. Cortegano, N. Serrano, B. del Rio, P. Martin, P. Gonzalo, M. A. R. Marcos, and M. L. Gaspar. 2007. A population of CD19highCD45R-/lowSD21low B lymphocytes poised for spontaneous secretion of IgG and IgA antibodies. J. Immunol. 179: 5326–5334.
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