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J Immunol (2007) 179 (9): 5615–5616.

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PILLARS OF IMMUNOLOGY

Nossal and Pike 1975: A Turning Point in the Effort to Define Self-Tolerance Mechanisms

Christopher C. Goodnow

J Immunol (2007) 179 (9): 5617–5618.

View articletitled, Nossal and Pike 1975: A Turning Point in the Effort to Define Self-Tolerance Mechanisms

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Pillars Article: Evidence for the Clonal Abortion Theory of B-Lymphocyte Tolerance. J. Exp. Med. 1975. 141: 904–917.

G. J. V. Nossal; Beverley L. Pike

J Immunol (2007) 179 (9): 5619–5632.

View articletitled, Pillars Article: Evidence for the Clonal Abortion Theory of B-Lymphocyte Tolerance. <em>J. Exp. Med.</em> 1975. 141: 904–917.

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BRIEF REVIEWS

Perspectives on Mucosal Vaccines: Is Mucosal Tolerance a Barrier?¹

Jiri Mestecky; Michael W. Russell; Charles O. Elson

J Immunol (2007) 179 (9): 5633–5638.

View articletitled, Perspectives on Mucosal Vaccines: Is Mucosal Tolerance a Barrier?<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: Two Distinct Motifs within the Fas Ligand Tail Regulate Fas Ligand-Mediated Costimulation ¹

Mingyi Sun; Shinhee Lee; Saoussen Karray; Matthieu Levi-Strauss; Kristina T. Ames; Pamela J. Fink

J Immunol (2007) 179 (9): 5639–5643.

View articletitled, Cutting Edge: Two Distinct Motifs within the Fas Ligand Tail Regulate Fas Ligand-Mediated Costimulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Modulation of Intestinal Autoimmunity and IL-2 Signaling by Sphingosine Kinase 2 Independent of Sphingosine 1-Phosphate ¹

Eileen T. Samy; Claas A. Meyer; Patrick Caplazi; Claire L. Langrish; Jose M. Lora; Horst Bluethmann; Stanford L. Peng

J Immunol (2007) 179 (9): 5644–5648.

View articletitled, Cutting Edge: Modulation of Intestinal Autoimmunity and IL-2 Signaling by Sphingosine Kinase 2 Independent of Sphingosine 1-Phosphate<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Atypical PKCs Regulate T Lymphocyte Polarity and Scanning Behavior ¹

Eliana Real; Sophie Faure; Emmanuel Donnadieu; Jérôme Delon

J Immunol (2007) 179 (9): 5649–5652.

View articletitled, Cutting Edge: Atypical PKCs Regulate T Lymphocyte Polarity and Scanning Behavior<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: TCR Revision Affects Predominantly Foxp3⁻ Cells and Skews Them toward the Th17 Lineage ¹

Dietmar Zehn; Michael J. Bevan; Pamela J. Fink

J Immunol (2007) 179 (9): 5653–5657.

View articletitled, Cutting Edge: TCR Revision Affects Predominantly Foxp3<sup>−</sup> Cells and Skews Them toward the Th17 Lineage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

How Regulatory CD25⁺CD4⁺ T Cells Impinge on Tumor Immunobiology: The Differential Response of Tumors to Therapies

Kalet Leon; Karina Garcia; Jorge Carneiro; Agustin Lage

J Immunol (2007) 179 (9): 5659–5668.

View articletitled, How Regulatory CD25<sup>+</sup>CD4<sup>+</sup> T Cells Impinge on Tumor Immunobiology: The Differential Response of Tumors to Therapies

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Histone Acetylation at the Ifng Promoter in Tolerized CD4 Cells Is Associated with Increased IFN-γ Expression during Subsequent Immunization to the Same Antigen ¹

Meixiao Long; Aaron M. Slaiby; Shuang Wu; Adam T. Hagymasi; Marianne A. Mihalyo; Suman Bandyopadhyay; Anthony T. Vella; Adam J. Adler

J Immunol (2007) 179 (9): 5669–5677.

View articletitled, Histone Acetylation at the <em>Ifng</em> Promoter in Tolerized CD4 Cells Is Associated with Increased IFN-γ Expression during Subsequent Immunization to the Same Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Targeting the Gut Vascular Endothelium Induces Gut Effector CD8 T Cell Responses Via Cross-Presentation by Dendritic Cells ¹

Dorothee Bourges; Yifan Zhan; Jamie L. Brady; Hal Braley; Irina Caminschi; Sandro Prato; José A. Villadangos; Andrew M. Lew

J Immunol (2007) 179 (9): 5678–5685.

View articletitled, Targeting the Gut Vascular Endothelium Induces Gut Effector CD8 T Cell Responses Via Cross-Presentation by Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Distinct Role of Neutrophil Lactoferrin in RelA/p65 Phosphorylation on Ser⁵³⁶ by Recruiting TNF Receptor-Associated Factors to IκB Kinase Signaling Complex ¹

Sang-Muk Oh; Shin-Hee Lee; Bum-Jin Lee; Chul-Woong Pyo; Na-Kyung Yoo; Soo Young Lee; Jiyoung Kim; Sang-Yun Choi

J Immunol (2007) 179 (9): 5686–5692.

View articletitled, A Distinct Role of Neutrophil Lactoferrin in RelA/p65 Phosphorylation on Ser<sup>536</sup> by Recruiting TNF Receptor-Associated Factors to IκB Kinase Signaling Complex<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lymphotoxin Pathway and Aire Influences on Thymic Medullary Epithelial Cells Are Unconnected ¹

Emily S. Venanzi; Daniel H. D. Gray; Christophe Benoist; Diane Mathis

J Immunol (2007) 179 (9): 5693–5700.

View articletitled, Lymphotoxin Pathway and Aire Influences on Thymic Medullary Epithelial Cells Are Unconnected<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Sialyl-Lewis^x on P-Selectin Glycoprotein Ligand-1 Is Regulated during Differentiation and Maturation of Dendritic Cells: A Mechanism Involving the Glycosyltransferases C2GnT1 and ST3Gal I ¹

Sylvain Julien; Matthew J. Grimshaw; Mark Sutton-Smith; Julia Coleman; Howard R. Morris; Anne Dell; Joyce Taylor-Papadimitriou; Joy M. Burchell

J Immunol (2007) 179 (9): 5701–5710.

View articletitled, Sialyl-Lewis<sup>x</sup> on P-Selectin Glycoprotein Ligand-1 Is Regulated during Differentiation and Maturation of Dendritic Cells: A Mechanism Involving the Glycosyltransferases C2GnT1 and ST3Gal I<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Calcineurin Inhibitors Block MHC-Restricted Antigen Presentation In Vivo ¹

Young-Hee Lee; Young-Ran Lee; Sun-A Im; Sun-Im Park; Ki-Hyang Kim; Turmunkh Gerelchuluun; Sukgil Song; Kyungjae Kim; Chong-Kil Lee

J Immunol (2007) 179 (9): 5711–5716.

View articletitled, Calcineurin Inhibitors Block MHC-Restricted Antigen Presentation In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Molecular Architecture of the TAP-Associated MHC Class I Peptide-Loading Complex ¹

Elke Rufer; Ralf M. Leonhardt; Michael R. Knittler

J Immunol (2007) 179 (9): 5717–5727.

View articletitled, Molecular Architecture of the TAP-Associated MHC Class I Peptide-Loading Complex<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Regulation of the Nature and Functions of Dendritic Cells and Macrophages by Cathepsin E

Hiroe Kakehashi; Tsuyoshi Nishioku; Takayuki Tsukuba; Tomoko Kadowaki; Seiji Nakamura; Kenji Yamamoto

J Immunol (2007) 179 (9): 5728–5737.

View articletitled, Differential Regulation of the Nature and Functions of Dendritic Cells and Macrophages by Cathepsin E

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Increasing the Survival of Dendritic Cells In Vivo Does Not Replace the Requirement for CD4⁺ T Cell Help during Primary CD8⁺ T Cell Responses ¹

Kate E. Matthews; Jim S. Qin; Jianping Yang; Ian F. Hermans; Michael J. Palmowski; Vincenzo Cerundolo; Franca Ronchese

J Immunol (2007) 179 (9): 5738–5747.

View articletitled, Increasing the Survival of Dendritic Cells In Vivo Does Not Replace the Requirement for CD4<sup>+</sup> T Cell Help during Primary CD8<sup>+</sup> T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Allergic Airways Disease Develops after an Increase in Allergen Capture and Processing in the Airway Mucosa ¹

Christophe von Garnier; Matthew E. Wikstrom; Graeme Zosky; Debra J. Turner; Peter D. Sly; Miranda Smith; Jennifer A. Thomas; Samantha R. Judd; Deborah H. Strickland; Patrick G. Holt; Philip A. Stumbles

J Immunol (2007) 179 (9): 5748–5759.

View articletitled, Allergic Airways Disease Develops after an Increase in Allergen Capture and Processing in the Airway Mucosa<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Recruitment and Activation of Macrophages by Pathogenic CD4 T Cells in Type 1 Diabetes: Evidence for Involvement of CCR8 and CCL1 ¹

Joseph Cantor; Kathryn Haskins

J Immunol (2007) 179 (9): 5760–5767.

View articletitled, Recruitment and Activation of Macrophages by Pathogenic CD4 T Cells in Type 1 Diabetes: Evidence for Involvement of CCR8 and CCL1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Extent of Stimulation Controls the Formation of Memory CD8 T Cells ¹

Michael Quigley; Xiaopei Huang; Yiping Yang

J Immunol (2007) 179 (9): 5768–5777.

View articletitled, Extent of Stimulation Controls the Formation of Memory CD8 T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Syndecan-4 Mediates the Coinhibitory Function of DC-HIL on T Cell Activation ¹

Jin-Sung Chung; Irene Dougherty; Ponciano D. Cruz, Jr.; Kiyoshi Ariizumi

J Immunol (2007) 179 (9): 5778–5784.

View articletitled, Syndecan-4 Mediates the Coinhibitory Function of DC-HIL on T Cell Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Evidence for In Vivo Primed and Expanded Autoreactive T Cells as a Specific Feature of Patients with Type 1 Diabetes ¹

Paolo Monti; Miriam Scirpoli; Andrea Rigamonti; Anya Mayr; Annika Jaeger; Riccardo Bonfanti; Giuseppe Chiumello; Anette G. Ziegler; Ezio Bonifacio

J Immunol (2007) 179 (9): 5785–5792.

View articletitled, Evidence for In Vivo Primed and Expanded Autoreactive T Cells as a Specific Feature of Patients with Type 1 Diabetes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Decay Accelerating Factor Can Control T Cell Differentiation into IFN-γ-Producing Effector Cells via Regulating Local C5a-Induced IL-12 Production ¹

Peter N. Lalli; Michael G. Strainic; Feng Lin; M. Edward Medof; Peter S. Heeger

J Immunol (2007) 179 (9): 5793–5802.

View articletitled, Decay Accelerating Factor Can Control T Cell Differentiation into IFN-γ-Producing Effector Cells via Regulating Local C5a-Induced IL-12 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Targeting the Wilms Tumor Antigen 1 by TCR Gene Transfer: TCR Variants Improve Tetramer Binding but Not the Function of Gene Modified Human T Cells ¹

Sharyn Thomas; Shao-An Xue; Michela Cesco-Gaspere; Esther San José; Daniel P. Hart; Vivian Wong; Reno Debets; Balbino Alarcon; Emma Morris; Hans J. Stauss

J Immunol (2007) 179 (9): 5803–5810.

View articletitled, Targeting the Wilms Tumor Antigen 1 by TCR Gene Transfer: TCR Variants Improve Tetramer Binding but Not the Function of Gene Modified Human T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-6 and Maturation Govern TLR2 and TLR4 Induced TLR Agonist Tolerance and Cross-Tolerance in Dendritic Cells ¹

Julia Geisel; Frauke Kahl; Martina Müller; Hermann Wagner; Carsten J. Kirschning; Ingo B. Autenrieth; Julia-Stefanie Frick

J Immunol (2007) 179 (9): 5811–5818.

View articletitled, IL-6 and Maturation Govern TLR2 and TLR4 Induced TLR Agonist Tolerance and Cross-Tolerance in Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Autoimmunity Stimulated by Adoptively Transferred Dendritic Cells Is Initiated by Both αβ and γδ T Cells but Does Not Require MyD88 Signaling ¹

David A. Martin; Kang Zhang; Justin Kenkel; Grant Hughes; Edward Clark; Anne Davidson; Keith B. Elkon

J Immunol (2007) 179 (9): 5819–5828.

View articletitled, Autoimmunity Stimulated by Adoptively Transferred Dendritic Cells Is Initiated by Both αβ and γδ T Cells but Does Not Require MyD88 Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cognate Memory CD4⁺ T Cells Generated with Dendritic Cell Priming Influence the Expansion, Trafficking, and Differentiation of Secondary CD8⁺ T Cells and Enhance Tumor Control ¹

Melissa L. Hwang; John R. Lukens; Timothy N. J. Bullock

J Immunol (2007) 179 (9): 5829–5838.

View articletitled, Cognate Memory CD4<sup>+</sup> T Cells Generated with Dendritic Cell Priming Influence the Expansion, Trafficking, and Differentiation of Secondary CD8<sup>+</sup> T Cells and Enhance Tumor Control<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Functionally Coupled μ3-Like Opiate Receptor/Nitric Oxide Regulatory Pathway in Human Multi-Lineage Progenitor Cells ¹

Patrick Cadet; Kirk J. Mantione; Wei Zhu; Richard M. Kream; Melinda Sheehan; George B. Stefano

J Immunol (2007) 179 (9): 5839–5844.

View articletitled, A Functionally Coupled μ3-Like Opiate Receptor/Nitric Oxide Regulatory Pathway in Human Multi-Lineage Progenitor Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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High-Affinity TCRs Generated by Phage Display Provide CD4⁺ T Cells with the Ability to Recognize and Kill Tumor Cell Lines ¹

Yangbing Zhao; Alan D. Bennett; Zhili Zheng; Qiong J. Wang; Paul F. Robbins; Lawrence Y. L. Yu; Yi Li; Peter E. Molloy; Steven M. Dunn; Bent K. Jakobsen; Steven A. Rosenberg; Richard A. Morgan

J Immunol (2007) 179 (9): 5845–5854.

View articletitled, High-Affinity TCRs Generated by Phage Display Provide CD4<sup>+</sup> T Cells with the Ability to Recognize and Kill Tumor Cell Lines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Sphingosine-1 Phosphate Signaling Regulates Positioning of Dendritic Cells within the Spleen ¹

Niklas Czeloth; Angela Schippers; Norbert Wagner; Werner Müller; Birgit Küster; Günter Bernhardt; Reinhold Förster

J Immunol (2007) 179 (9): 5855–5863.

View articletitled, Sphingosine-1 Phosphate Signaling Regulates Positioning of Dendritic Cells within the Spleen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Quantitative Time-Resolved Phosphoproteomic Analysis of Mast Cell Signaling ¹

Lulu Cao; Kebing Yu; Cindy Banh; Vinh Nguyen; Anna Ritz; Benjamin J. Raphael; Yuko Kawakami; Toshiaki Kawakami; Arthur R. Salomon

J Immunol (2007) 179 (9): 5864–5876.

View articletitled, Quantitative Time-Resolved Phosphoproteomic Analysis of Mast Cell Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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B Cell Activation State-Governed Formation of Germinal Centers following Viral Infection ¹

Katja Fink; Nataly Manjarrez-Orduño; Anita Schildknecht; Jacqueline Weber; Beatrice M. Senn; Rolf M. Zinkernagel; Hans Hengartner

J Immunol (2007) 179 (9): 5877–5885.

View articletitled, B Cell Activation State-Governed Formation of Germinal Centers following Viral Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Essential Role of IL-21 in B Cell Activation, Expansion, and Plasma Cell Generation during CD4⁺ T Cell-B Cell Collaboration ¹

Stefan Kuchen; Rachel Robbins; Gary P. Sims; Chen Sheng; Terence M. Phillips; Peter E. Lipsky; Rachel Ettinger

J Immunol (2007) 179 (9): 5886–5896.

View articletitled, Essential Role of IL-21 in B Cell Activation, Expansion, and Plasma Cell Generation during CD4<sup>+</sup> T Cell-B Cell Collaboration<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulatory Role of Lymphoid Chemokine CCL19 and CCL21 in the Control of Allergic Rhinitis ¹

Kaoru Takamura; Satoshi Fukuyama; Takahiro Nagatake; Dong-Young Kim; Aya Kawamura; Hideyuki Kawauchi; Hiroshi Kiyono

J Immunol (2007) 179 (9): 5897–5906.

View articletitled, Regulatory Role of Lymphoid Chemokine CCL19 and CCL21 in the Control of Allergic Rhinitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Posttranslational Regulation of I-E^d by Affinity for CLIP ¹

Cornelia H. Rinderknecht; Michael P. Belmares; Tatiana L. W. Catanzarite; Alexander J. Bankovich; Tyson H. Holmes; K. Christopher Garcia; Navreet K. Nanda; Robert Busch; Susan Kovats; Elizabeth D. Mellins

J Immunol (2007) 179 (9): 5907–5915.

View articletitled, Posttranslational Regulation of <em>I-E</em><sup><em>d</em></sup> by Affinity for CLIP<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Glucocorticoid-Induced TNFR-Related Protein Lowers the Threshold of CD28 Costimulation in CD8⁺ T Cells ¹

Simona Ronchetti; Giuseppe Nocentini; Rodolfo Bianchini; L. Tibor Krausz; Graziella Migliorati; Carlo Riccardi

J Immunol (2007) 179 (9): 5916–5926.

View articletitled, Glucocorticoid-Induced TNFR-Related Protein Lowers the Threshold of CD28 Costimulation in CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cyclosporin A Suspends Transplantation Reactions in the Marine Sponge Microciona prolifera¹

Clarissa Sabella; Ellen Faszewski; Lisa Himic; Katherine M. Colpitts; Jane Kaltenbach; Max M. Burger; Xavier Fernàndez-Busquets

J Immunol (2007) 179 (9): 5927–5935.

View articletitled, Cyclosporin A Suspends Transplantation Reactions in the Marine Sponge <em>Microciona prolifera</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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CD86 Has Sustained Costimulatory Effects on CD8 T Cells ¹

Ian J. Thomas; Liliana G. Petrich de Marquesini; Rommel Ravanan; Richard M. Smith; Sylvie Guerder; Richard A. Flavell; David C. Wraith; Li Wen; F. Susan Wong

J Immunol (2007) 179 (9): 5936–5946.

View articletitled, CD86 Has Sustained Costimulatory Effects on CD8 T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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In Vitro and In Vivo Activation Induces BAFF and APRIL Expression in B Cells ¹

Van Trung Chu; Philipp Enghard; Gabriela Riemekasten; Claudia Berek

J Immunol (2007) 179 (9): 5947–5957.

View articletitled, In Vitro and In Vivo Activation Induces BAFF and APRIL Expression in B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis ¹

Zhaojun Wang; Ju Qiu; Taylor B. Guo; Ailian Liu; Ying Wang; Yin Li; Jingwu Z. Zhang

J Immunol (2007) 179 (9): 5958–5965.

View articletitled, Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Molecular Mechanism of Lipopolysaccharide-Induced SOCS-3 Gene Expression in Macrophages and Microglia ¹

Hongwei Qin; Kevin L. Roberts; Sandrine A. Niyongere; Yingzi Cong; Charles O. Elson; Etty N. Benveniste

J Immunol (2007) 179 (9): 5966–5976.

View articletitled, Molecular Mechanism of Lipopolysaccharide-Induced SOCS-3 Gene Expression in Macrophages and Microglia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Hierarchy of the Human Natural Killer Cell Response Is Determined by Class and Quantity of Inhibitory Receptors for Self-HLA-B and HLA-C Ligands ¹

Junli Yu; Glenn Heller; Joseph Chewning; Sungjin Kim; Wayne M. Yokoyama; Katharine C. Hsu

J Immunol (2007) 179 (9): 5977–5989.

View articletitled, Hierarchy of the Human Natural Killer Cell Response Is Determined by Class and Quantity of Inhibitory Receptors for Self-HLA-B and HLA-C Ligands<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Jagged1 and Delta1 Differentially Regulate the Outcome of Experimental Autoimmune Encephalomyelitis ¹

Wassim Elyaman; Elizabeth M. Bradshaw; Yue Wang; Mohamed Oukka; Pia Kivisäkk; Shigeru Chiba; Hideo Yagita; Samia J. Khoury

J Immunol (2007) 179 (9): 5990–5998.

View articletitled, Jagged1 and Delta1 Differentially Regulate the Outcome of Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Functional yet Balanced Reactivity to Candida albicans Requires TRIF, MyD88, and IDO-Dependent Inhibition of Rorc¹

Antonella De Luca; Claudia Montagnoli; Teresa Zelante; Pierluigi Bonifazi; Silvia Bozza; Silvia Moretti; Carmen D’Angelo; Carmine Vacca; Louis Boon; Francesco Bistoni; Paolo Puccetti; Francesca Fallarino; Luigina Romani

J Immunol (2007) 179 (9): 5999–6008.

View articletitled, Functional yet Balanced Reactivity to <em>Candida albicans</em> Requires TRIF, MyD88, and IDO-Dependent Inhibition of <em>Rorc</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Crucial Role for Dendritic Cell (DC) IL-10 in Inhibiting Successful DC-Based Immunotherapy: Superior Antitumor Immunity against Hepatocellular Carcinoma Evoked by DC Devoid of IL-10 ¹

Yu-Xiao Chen; Kwan Man; Guang Sheng Ling; Yichen Chen; Bai-Shun Sun; Qiao Cheng; On Hong Wong; Chi-Kin Lo; Irene Oi-Lin Ng; Li Chong Chan; George K. Lau; Chen-Lung Steve Lin; Fanglu Huang; Fang-Ping Huang

J Immunol (2007) 179 (9): 6009–6015.

View articletitled, A Crucial Role for Dendritic Cell (DC) IL-10 in Inhibiting Successful DC-Based Immunotherapy: Superior Antitumor Immunity against Hepatocellular Carcinoma Evoked by DC Devoid of IL-10<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Purinergic P2Y₂ Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages ¹

Leanne Stokes; Annmarie Surprenant

J Immunol (2007) 179 (9): 6016–6023.

View articletitled, Purinergic P2Y<sub>2</sub> Receptors Induce Increased MCP-1/CCL2 Synthesis and Release from Rat Alveolar and Peritoneal Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Geranylgeranylation but Not GTP Loading Determines Rho Migratory Function in T Cells ¹

Sonia Waiczies; Ivo Bendix; Timour Prozorovski; Maya Ratner; Irina Nazarenko; Caspar F. Pfueller; Alexander U. Brandt; Josephine Herz; Stefan Brocke; Oliver Ullrich; Frauke Zipp

J Immunol (2007) 179 (9): 6024–6032.

View articletitled, Geranylgeranylation but Not GTP Loading Determines Rho Migratory Function in T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The 3′ IgH Locus Control Region Is Sufficient to Deregulate a c-myc Transgene and Promote Mature B Cell Malignancies with a Predominant Burkitt-Like Phenotype ¹

Véronique Truffinet; Eric Pinaud; Nadine Cogné; Barbara Petit; Laurence Guglielmi; Michel Cogné; Yves Denizot

J Immunol (2007) 179 (9): 6033–6042.

View articletitled, The 3′ <em>IgH</em> Locus Control Region Is Sufficient to Deregulate a c-<em>myc</em> Transgene and Promote Mature B Cell Malignancies with a Predominant Burkitt-Like Phenotype<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis ¹

Nathalie Decologne; Martin Kolb; Peter J. Margetts; Franck Menetrier; Yves Artur; Carmen Garrido; Jack Gauldie; Philippe Camus; Philippe Bonniaud

J Immunol (2007) 179 (9): 6043–6051.

View articletitled, TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Novel Endocytic and Phagocytic C-Type Lectin Receptor DCL-1/CD302 on Macrophages Is Colocalized with F-Actin, Suggesting a Role in Cell Adhesion and Migration ¹

Masato Kato; Seema Khan; Elisabetta d’Aniello; Kylie J. McDonald; Derek N. J. Hart

J Immunol (2007) 179 (9): 6052–6063.

View articletitled, The Novel Endocytic and Phagocytic C-Type Lectin Receptor DCL-1/CD302 on Macrophages Is Colocalized with F-Actin, Suggesting a Role in Cell Adhesion and Migration<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G₁ Phase of the Cell Cycle and Depend upon Mismatch Repair ¹

Carol E. Schrader; Jeroen E. J. Guikema; Erin K. Linehan; Erik Selsing; Janet Stavnezer

J Immunol (2007) 179 (9): 6064–6071.

View articletitled, Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G<sub>1</sub> Phase of the Cell Cycle and Depend upon Mismatch Repair<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

Mast Cell α and β Tryptases Changed Rapidly during Primate Speciation and Evolved from γ-Like Transmembrane Peptidases in Ancestral Vertebrates ¹

Neil N. Trivedi; Qiao Tong; Kavita Raman; Vikash J. Bhagwandin; George H. Caughey

J Immunol (2007) 179 (9): 6072–6079.

View articletitled, Mast Cell α and β Tryptases Changed Rapidly during Primate Speciation and Evolved from γ-Like Transmembrane Peptidases in Ancestral Vertebrates<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

A Monocyte-Specific Peptide from Herpes Simplex Virus Type 2 Glycoprotein G Activates the NADPH-Oxidase but Not Chemotaxis through a G-Protein-Coupled Receptor Distinct from the Members of the Formyl Peptide Receptor Family ¹

Lars Bellner; Jennie Karlsson; Huamei Fu; François Boulay; Claes Dahlgren; Kristina Eriksson; Anna Karlsson

J Immunol (2007) 179 (9): 6080–6087.

View articletitled, A Monocyte-Specific Peptide from Herpes Simplex Virus Type 2 Glycoprotein G Activates the NADPH-Oxidase but Not Chemotaxis through a G-Protein-Coupled Receptor Distinct from the Members of the Formyl Peptide Receptor Family<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Pregnancy Impairs the Innate Immune Resistance to Salmonella typhimurium Leading to Rapid Fatal Infection ¹

Branka Pejcic-Karapetrovic; Komal Gurnani; Marsha S. Russell; B. Brett Finlay; Subash Sad; Lakshmi Krishnan

J Immunol (2007) 179 (9): 6088–6096.

View articletitled, Pregnancy Impairs the Innate Immune Resistance to <em>Salmonella typhimurium</em> Leading to Rapid Fatal Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tobacco Smoking Inhibits Expression of Proinflammatory Cytokines and Activation of IL-1R-Associated Kinase, p38, and NF-κB in Alveolar Macrophages Stimulated with TLR2 and TLR4 Agonists ¹

Haiyan Chen; Mark J. Cowan; Jeffrey D. Hasday; Stefanie N. Vogel; Andrei E. Medvedev

J Immunol (2007) 179 (9): 6097–6106.

View articletitled, Tobacco Smoking Inhibits Expression of Proinflammatory Cytokines and Activation of IL-1R-Associated Kinase, p38, and NF-κB in Alveolar Macrophages Stimulated with TLR2 and TLR4 Agonists<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR4/MD-2 Monoclonal Antibody Therapy Affords Protection in Experimental Models of Septic Shock

Bruno Daubeuf; John Mathison; Stephan Spiller; Stephanie Hugues; Suzanne Herren; Walter Ferlin; Marie Kosco-Vilbois; Hermann Wagner; Carsten J. Kirschning; Richard Ulevitch; Greg Elson

J Immunol (2007) 179 (9): 6107–6114.

View articletitled, TLR4/MD-2 Monoclonal Antibody Therapy Affords Protection in Experimental Models of Septic Shock

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Characterization of Antigen-Specific Immune Responses Induced by Canarypox Virus Vaccines ¹

Rinke Bos; Suzanne van Duikeren; Thorbald van Hall; Marjolein M. Lauwen; Mark Parrington; Neil L. Berinstein; Bryan McNeil; Cornelis J. M. Melief; J. Sjef Verbeek; Sjoerd H. van der Burg; Rienk Offringa

J Immunol (2007) 179 (9): 6115–6122.

View articletitled, Characterization of Antigen-Specific Immune Responses Induced by Canarypox Virus Vaccines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Type I IFN-Inducing Abilities of Wild-Type versus Vaccine Strains of Measles Virus ¹

Masashi Shingai; Takashi Ebihara; Nasim A. Begum; Atsushi Kato; Toshiki Honma; Kenji Matsumoto; Hirohisa Saito; Hisashi Ogura; Misako Matsumoto; Tsukasa Seya

J Immunol (2007) 179 (9): 6123–6133.

View articletitled, Differential Type I IFN-Inducing Abilities of Wild-Type versus Vaccine Strains of Measles Virus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR2 and Caspase-8 Are Essential for Group B Streptococcus-Induced Apoptosis in Microglia ¹

Seija Lehnardt; Julia Wennekamp; Dorette Freyer; Christian Liedtke; Christina Krueger; Robert Nitsch; Ingo Bechmann; Joerg R. Weber; Philipp Henneke

J Immunol (2007) 179 (9): 6134–6143.

View articletitled, TLR2 and Caspase-8 Are Essential for Group B <em>Streptococcus</em>-Induced Apoptosis in Microglia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Stromal Complement Receptor CD21/35 Facilitates Lymphoid Prion Colonization and Pathogenesis ¹

Mark D. Zabel; Mathias Heikenwalder; Marco Prinz; Isabelle Arrighi; Petra Schwarz; Jan Kranich; Adriana von Teichman; Karen M. Haas; Nicolas Zeller; Thomas F. Tedder; John H. Weis; Adriano Aguzzi

J Immunol (2007) 179 (9): 6144–6152.

View articletitled, Stromal Complement Receptor CD21/35 Facilitates Lymphoid Prion Colonization and Pathogenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Rectification of Age-Associated Deficiency in Cytotoxic T Cell Response to Influenza A Virus by Immunization with Immune Complexes

Biao Zheng; Yongxin Zhang; Hongxia He; Ekaterina Marinova; Kirsten Switzer; Daniel Wansley; Innocent Mbawuike; Shuhua Han

J Immunol (2007) 179 (9): 6153–6159.

View articletitled, Rectification of Age-Associated Deficiency in Cytotoxic T Cell Response to Influenza A Virus by Immunization with Immune Complexes

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VAP-1-Deficient Mice Display Defects in Mucosal Immunity and Antimicrobial Responses: Implications for Antiadhesive Applications ¹

Kaisa Koskinen; Suvi Nevalainen; Marika Karikoski; Arno Hänninen; Sirpa Jalkanen; Marko Salmi

J Immunol (2007) 179 (9): 6160–6168.

View articletitled, VAP-1-Deficient Mice Display Defects in Mucosal Immunity and Antimicrobial Responses: Implications for Antiadhesive Applications<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Salmonella Flagellin Induces Bystander Activation of Splenic Dendritic Cells and Hinders Bacterial Replication In Vivo ¹

Rosa-Maria Salazar-Gonzalez; Aparna Srinivasan; Amanda Griffin; Guruprasaadh Muralimohan; James M. Ertelt; Rajesh Ravindran; Anthony T. Vella; Stephen J. McSorley

J Immunol (2007) 179 (9): 6169–6175.

View articletitled, <em>Salmonella</em> Flagellin Induces Bystander Activation of Splenic Dendritic Cells and Hinders Bacterial Replication In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN-αβ-Mediated Inflammatory Responses and Antiviral Defense in Liver Is TLR9-Independent but MyD88-Dependent during Murine Cytomegalovirus Infection ¹

Kirsten L. Hokeness-Antonelli; Meredith J. Crane; Ana M. Dragoi; Wen-Ming Chu; Thais P. Salazar-Mather

J Immunol (2007) 179 (9): 6176–6183.

View articletitled, IFN-αβ-Mediated Inflammatory Responses and Antiviral Defense in Liver Is TLR9-Independent but MyD88-Dependent during Murine Cytomegalovirus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

Elastin Receptor (Spliced Galactosidase) Occupancy by Elastin Peptides Counteracts Proinflammatory Cytokine Expression in Lipopolysaccharide-Stimulated Human Monocytes through NF-κB Down-Regulation ¹

Thomas Baranek; Romain Debret; Frank Antonicelli; Bouchaib Lamkhioued; Azzaq Belaaouaj; William Hornebeck; Philippe Bernard; Moncef Guenounou; Richard Le Naour

J Immunol (2007) 179 (9): 6184–6192.

View articletitled, Elastin Receptor (Spliced Galactosidase) Occupancy by Elastin Peptides Counteracts Proinflammatory Cytokine Expression in Lipopolysaccharide-Stimulated Human Monocytes through NF-κB Down-Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Prostaglandin I₂-IP Signaling Blocks Allergic Pulmonary Inflammation by Preventing Recruitment of CD4⁺ Th2 Cells into the Airways in a Mouse Model of Asthma ¹

Zeina Jaffar; Maria E. Ferrini; Mary C. Buford; Garret A. FitzGerald; Kevan Roberts

J Immunol (2007) 179 (9): 6193–6203.

View articletitled, Prostaglandin I<sub>2</sub>-IP Signaling Blocks Allergic Pulmonary Inflammation by Preventing Recruitment of CD4<sup>+</sup> Th2 Cells into the Airways in a Mouse Model of Asthma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Urocortin Modulates Inflammatory Response and Neurotoxicity Induced by Microglial Activation ¹

Mei-Jen Wang; Shinn-Zong Lin; Jon-Son Kuo; Hsin-Yi Huang; Shih-Fang Tzeng; Chia-Hsin Liao; Der-Cherng Chen; Wu-Fu Chen

J Immunol (2007) 179 (9): 6204–6214.

View articletitled, Urocortin Modulates Inflammatory Response and Neurotoxicity Induced by Microglial Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lipopolysaccharide, IFN-γ, and IFN-β Induce Expression of the Thiol-Sensitive ART2.1 Ecto-ADP-Ribosyltransferase in Murine Macrophages ¹

Shiyuan Hong; Anette Brass; Michel Seman; Friedrich Haag; Friedrich Koch-Nolte; George R. Dubyak

J Immunol (2007) 179 (9): 6215–6227.

View articletitled, Lipopolysaccharide, IFN-γ, and IFN-β Induce Expression of the Thiol-Sensitive ART2.1 Ecto-ADP-Ribosyltransferase in Murine Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Exacerbation of Antigen-Induced Arthritis in IFN-γ-Deficient Mice As a Result of Unrestricted IL-17 Response ¹

Ingo M. Irmler; Mieczyslaw Gajda; Rolf Bräuer

J Immunol (2007) 179 (9): 6228–6236.

View articletitled, Exacerbation of Antigen-Induced Arthritis in IFN-γ-Deficient Mice As a Result of Unrestricted IL-17 Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Role of IκB Kinase 2, but Not Activation of NF-κB, in the Release of CXCR3 Ligands from IFN-γ-Stimulated Human Bronchial Epithelial Cells

Susan J. Tudhope; Matthew C. Catley; Peter S. Fenwick; Richard E. K. Russell; William L. Rumsey; Robert Newton; Peter J. Barnes; Louise E. Donnelly

J Immunol (2007) 179 (9): 6237–6245.

View articletitled, The Role of IκB Kinase 2, but Not Activation of NF-κB, in the Release of CXCR3 Ligands from IFN-γ-Stimulated Human Bronchial Epithelial Cells

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Biomechanical Signals Suppress TAK1 Activation to Inhibit NF-κB Transcriptional Activation in Fibrochondrocytes ¹

Shashi Madhavan; Mirela Anghelina; Danen Sjostrom; Anar Dossumbekova; Denis C. Guttridge; Sudha Agarwal

J Immunol (2007) 179 (9): 6246–6254.

View articletitled, Biomechanical Signals Suppress TAK1 Activation to Inhibit NF-κB Transcriptional Activation in Fibrochondrocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Role of Dendritic Cells in the Development of Acute Dextran Sulfate Sodium Colitis ¹

Bradford E. Berndt; Min Zhang; Gwo-Hsiao Chen; Gary B. Huffnagle; John Y. Kao

J Immunol (2007) 179 (9): 6255–6262.

View articletitled, The Role of Dendritic Cells in the Development of Acute Dextran Sulfate Sodium Colitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Vasoactive Hormone Adrenomedullin and Its Binding Protein: Anti-Inflammatory Effects by Up-Regulating Peroxisome Proliferator-Activated Receptor-γ ¹

Michael Miksa; Rongqian Wu; Xiaoxuan Cui; Weifeng Dong; Padmalaya Das; H. Hank Simms; Thanjavur S. Ravikumar; Ping Wang

J Immunol (2007) 179 (9): 6263–6272.

View articletitled, Vasoactive Hormone Adrenomedullin and Its Binding Protein: Anti-Inflammatory Effects by Up-Regulating Peroxisome Proliferator-Activated Receptor-γ<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Topically Applied 1,25-Dihydroxyvitamin D₃ Enhances the Suppressive Activity of CD4⁺CD25⁺ Cells in the Draining Lymph Nodes ¹

Shelley Gorman; L. Alexandra Kuritzky; Melinda A. Judge; Katie M. Dixon; Jacqueline P. McGlade; Rebecca S. Mason; John J. Finlay-Jones; Prue H. Hart

J Immunol (2007) 179 (9): 6273–6283.

View articletitled, Topically Applied 1,25-Dihydroxyvitamin D<sub>3</sub> Enhances the Suppressive Activity of CD4<sup>+</sup>CD25<sup>+</sup> Cells in the Draining Lymph Nodes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Estradiol Attenuates Lipopolysaccharide-Induced CXC Chemokine Ligand 8 Production by Human Peripheral Blood Monocytes

Patricia A. Pioli; Amy L. Jensen; Lehn K. Weaver; Eyal Amiel; Zheng Shen; Li Shen; Charles R. Wira; Paul M. Guyre

J Immunol (2007) 179 (9): 6284–6290.

View articletitled, Estradiol Attenuates Lipopolysaccharide-Induced CXC Chemokine Ligand 8 Production by Human Peripheral Blood Monocytes

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Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF-κB-Inducing Kinase ¹

Janelle C. Arthur; John D. Lich; Ramy K. Aziz; Malak Kotb; Jenny P.-Y. Ting

J Immunol (2007) 179 (9): 6291–6296.

View articletitled, Heat Shock Protein 90 Associates with Monarch-1 and Regulates Its Ability to Promote Degradation of NF-κB-Inducing Kinase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Nerve Growth Factor Promotes TLR4 Signaling-Induced Maturation of Human Dendritic Cells In Vitro through Inducible p75^{NTR 1}

Yingming Jiang; Guoyou Chen; Yi Zhang; Lin Lu; Shuxun Liu; Xuetao Cao

J Immunol (2007) 179 (9): 6297–6304.

View articletitled, Nerve Growth Factor Promotes TLR4 Signaling-Induced Maturation of Human Dendritic Cells In Vitro through Inducible p75<sup>NTR 1</sup>

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HVEM Signaling in Monocytes Is Mediated by Intracellular Calcium Mobilization ¹

Sook-Kyoung Heo; Min-A Yoon; Sang-Chul Lee; Seong-A Ju; Jang-Hyun Choi; Pann-Ghill Suh; Byoung S. Kwon; Byung-Sam Kim

J Immunol (2007) 179 (9): 6305–6310.

View articletitled, HVEM Signaling in Monocytes Is Mediated by Intracellular Calcium Mobilization<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3 ¹

Alessia Cotena; Virginia Maina; Marina Sironi; Barbara Bottazzi; Pascale Jeannin; Annunciata Vecchi; Nathalie Corvaia; Mohamed R. Daha; Alberto Mantovani; Cecilia Garlanda

J Immunol (2007) 179 (9): 6311–6317.

View articletitled, Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Hsp72 Induces Inflammation and Regulates Cytokine Production in Airway Epithelium through a TLR4- and NF-κB-Dependent Mechanism ¹

Margaret A. Chase; Derek S. Wheeler; Kristin M. Lierl; Valerie S. Hughes; Hector R. Wong; Kristen Page

J Immunol (2007) 179 (9): 6318–6324.

View articletitled, Hsp72 Induces Inflammation and Regulates Cytokine Production in Airway Epithelium through a TLR4- and NF-κB-Dependent Mechanism<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Macrophages from 11β-Hydroxysteroid Dehydrogenase Type 1-Deficient Mice Exhibit an Increased Sensitivity to Lipopolysaccharide Stimulation Due to TGF-β-Mediated Up-Regulation of SHIP1 Expression

Tian Y. Zhang; Raymond A. Daynes

J Immunol (2007) 179 (9): 6325–6335.

View articletitled, Macrophages from 11β-Hydroxysteroid Dehydrogenase Type 1-Deficient Mice Exhibit an Increased Sensitivity to Lipopolysaccharide Stimulation Due to TGF-β-Mediated Up-Regulation of SHIP1 Expression

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CLINICAL IMMUNOLOGY

Decline in the Frequencies of Borrelia burgdorferi OspA_161–175-Specific T Cells after Antibiotic Therapy in HLA-DRB1*0401-Positive Patients with Antibiotic-Responsive or Antibiotic-Refractory Lyme Arthritis ¹

Priya Kannian; Elise E. Drouin; Lisa Glickstein; William W. Kwok; Gerald T. Nepom; Allen C. Steere

J Immunol (2007) 179 (9): 6336–6342.

View articletitled, Decline in the Frequencies of <em>Borrelia burgdorferi</em> OspA<sub>161–175</sub>-Specific T Cells after Antibiotic Therapy in HLA-DRB1*0401-Positive Patients with Antibiotic-Responsive or Antibiotic-Refractory Lyme Arthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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V_H4 Gene Segments Dominate the Intrathecal Humoral Immune Response in Multiple Sclerosis ¹

Gregory P. Owens; Kimberly M. Winges; Alanna M. Ritchie; Sydni Edwards; Mark P. Burgoon; Laura Lehnhoff; Kirsten Nielsen; John Corboy; Donald H. Gilden; Jeffrey L. Bennett

J Immunol (2007) 179 (9): 6343–6351.

View articletitled, V<sub>H</sub>4 Gene Segments Dominate the Intrathecal Humoral Immune Response in Multiple Sclerosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Demethylation of CD40LG on the Inactive X in T Cells from Women with Lupus ¹

Qianjin Lu; Ailing Wu; Laura Tesmer; Donna Ray; Neda Yousif; Bruce Richardson

J Immunol (2007) 179 (9): 6352–6358.

View articletitled, Demethylation of <em>CD40LG</em> on the Inactive X in T Cells from Women with Lupus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Rheumatoid Arthritis Shared Epitope Triggers Innate Immune Signaling via Cell Surface Calreticulin ¹

Song Ling; Xiujun Pi; Joseph Holoshitz

J Immunol (2007) 179 (9): 6359–6367.

View articletitled, The Rheumatoid Arthritis Shared Epitope Triggers Innate Immune Signaling via Cell Surface Calreticulin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

Protection from lethal infection by adoptive transfer of CD8 T cells genetically engineered to express virus-specific innate immune receptor.

K. Iizuka; C. Nakajima; Y.-M. Iizuka; M. Takase; T. Kato; S. Noda; K. Tanaka; O. Kanagawa

J Immunol (2007) 179 (9): 6368.

View articletitled, Protection from lethal infection by adoptive transfer of CD8 T cells genetically engineered to express virus-specific innate immune receptor.

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The endothelial cell-produced anti-angiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.

F. Tian; S. Grimaldo; M. Fugita; J. Cutts; N. L. Vujanovic; L.-Y. Li

J Immunol (2007) 179 (9): 6369.

View articletitled, The endothelial cell-produced anti-angiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.

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Bruton’s tyrosine kinase mediates NF-κB activation and B cell survival by B cell-activating factor receptor of the TNF-R family.

N. P. Shinners; G. Carlesso; I. Castro; K. L. Hoek; R. A. Corn; R. L. Woodland; M. L. Scott; D. Wang; W. N. Khan

J Immunol (2007) 179 (9): 6369.

View articletitled, Bruton’s tyrosine kinase mediates NF-κB activation and B cell survival by B cell-activating factor receptor of the TNF-R family.

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Cover Image

Cover Image

On the cover: TGF-β1 induces phenotypic transition and migration of mesothelial cells in the context of pleural fibrosis, a process called "mesothelial fibroblastoid transformation." The image shows a rat pleura 7 days after adenoviral gene transfer of TGF-β1 to the pleural mesothelium. Immunofluorescence identifies cells with dual positivity for mesothelial (cytokeratin, green) and myofibroblast-like (α-SMA, red) markers. Decologne, N., M. Kolb, P. J. Margetts, F. Menetrier, Y. Artur, C. Garrido, J. Gauldie, P. Camus, and P. Bonniaud. 2007. TGF-β1 induces progressive pleural scarring and subpleural fibrosis. J. Immunol. 179: 6043–6051.
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