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J Immunol (2008) 180 (4): 2005–2006.

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LETTERS TO THE EDITOR

Comment on “TCR Activation Eliminates Glutamate Receptor GluR3 from the Cell Surface of Normal Human T Cells, via an Autocrine/Paracrine Granzyme B-Mediated Proteolytic Cleavage”

Cornelia Poulopoulou

J Immunol (2008) 180 (4): 2007.

View articletitled, Comment on “TCR Activation Eliminates Glutamate Receptor GluR3 from the Cell Surface of Normal Human T Cells, via an Autocrine/Paracrine Granzyme B-Mediated Proteolytic Cleavage”

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Response to Comment on “TCR Activation Eliminates Glutamate Receptor GluR3 from the Cell Surface of Normal Human T Cells, via an Autocrine/Paracrine Granzyme B-Mediated Proteolytic Cleavage”

Mia Levite

J Immunol (2008) 180 (4): 2007.

View articletitled, Response to Comment on “TCR Activation Eliminates Glutamate Receptor GluR3 from the Cell Surface of Normal Human T Cells, via an Autocrine/Paracrine Granzyme B-Mediated Proteolytic Cleavage”

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Comment on “Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome”

Olivier Thaunat; Antonino Nicoletti

J Immunol (2008) 180 (4): 2007–2008.

View articletitled, Comment on “Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome”

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Response to Comment on “Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome”

Michele Bombardieri; Francesca Barone; Costantino Pitzalis

J Immunol (2008) 180 (4): 2008–2009.

View articletitled, Response to Comment on “Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjögren’s Syndrome”

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Comment on “Resistin-Like Molecule β (RELMβ/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis”

Sicheng Wen; Christian P. Felley; Vera Kessler; Pierre Michetti; Qiang Pan-Hammarström

J Immunol (2008) 180 (4): 2009.

View articletitled, Comment on “Resistin-Like Molecule β (RELMβ/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis”

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Response to Comment on “Resistin-Like Molecule β (RELM β/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis”

Steven M. Cohn; Alda Vidrich

J Immunol (2008) 180 (4): 2009–2010.

View articletitled, Response to Comment on “Resistin-Like Molecule β (RELM β/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis”

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BRIEF REVIEWS

Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms ¹

Subhra K. Biswas; Antonio Sica; Claire E. Lewis

J Immunol (2008) 180 (4): 2011–2017.

View articletitled, Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: A cis-Acting DNA Element Targets AID-Mediated Sequence Diversification to the Chicken Ig Light Chain Gene Locus ¹

Nagarama Kothapalli; Darrell D. Norton; Sebastian D. Fugmann

J Immunol (2008) 180 (4): 2019–2023.

View articletitled, Cutting Edge: A <em>cis</em>-Acting DNA Element Targets AID-Mediated Sequence Diversification to the Chicken Ig Light Chain Gene Locus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Activation by Innate Cytokines or Microbial Antigens Can Cause Arrest of Natural Killer T Cell Patrolling of Liver Sinusoids ¹

Peter Velázquez; Thomas O. Cameron; Yuki Kinjo; Niranjana Nagarajan; Mitchell Kronenberg; Michael L. Dustin

J Immunol (2008) 180 (4): 2024–2028.

View articletitled, Cutting Edge: Activation by Innate Cytokines or Microbial Antigens Can Cause Arrest of Natural Killer T Cell Patrolling of Liver Sinusoids<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: Progesterone Regulates IFN-α Production by Plasmacytoid Dendritic Cells ¹

Grant C. Hughes; Sunil Thomas; Chang Li; Murali-Krishna Kaja; Edward A. Clark

J Immunol (2008) 180 (4): 2029–2033.

View articletitled, Cutting Edge: Progesterone Regulates IFN-α Production by Plasmacytoid Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway ¹

Julien Pothlichet; Michel Chignard; Mustapha Si-Tahar

J Immunol (2008) 180 (4): 2034–2038.

View articletitled, Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: CD4 T Cell-Mast Cell Interactions Alter IgE Receptor Expression and Signaling ¹

Mohit Kashyap; Angela M. Thornton; Sarah Kennedy Norton; Brian Barnstein; Matthew Macey; Jennifer Brenzovich; Ethan Shevach; Warren J. Leonard; John J. Ryan

J Immunol (2008) 180 (4): 2039–2043.

View articletitled, Cutting Edge: CD4 T Cell-Mast Cell Interactions Alter IgE Receptor Expression and Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells ¹

Lina A. Thorén; Karina Liuba; David Bryder; Jens M. Nygren; Christina T. Jensen; Hong Qian; Jennifer Antonchuk; Sten-Eirik W. Jacobsen

J Immunol (2008) 180 (4): 2045–2053.

View articletitled, Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Critical Roles of the p110β Subtype of Phosphoinositide 3-Kinase in Lipopolysaccharide-Induced Akt Activation and Negative Regulation of Nitrite Production in RAW 264.7 Cells

Ken Tsukamoto; Kaoru Hazeki; Megumi Hoshi; Kiyomi Nigorikawa; Norimitsu Inoue; Takehiko Sasaki; Osamu Hazeki

J Immunol (2008) 180 (4): 2054–2061.

View articletitled, Critical Roles of the p110β Subtype of Phosphoinositide 3-Kinase in Lipopolysaccharide-Induced Akt Activation and Negative Regulation of Nitrite Production in RAW 264.7 Cells

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4-1BB Engagement Costimulates NKT Cell Activation and Exacerbates NKT Cell Ligand-Induced Airway Hyperresponsiveness and Inflammation ¹

Dong-Hyeon Kim; Woo-Sung Chang; Yoon-Sook Lee; Kyoo-A Lee; Yoon-Keun Kim; Byoung S. Kwon; Chang-Yuil Kang

J Immunol (2008) 180 (4): 2062–2068.

View articletitled, 4-1BB Engagement Costimulates NKT Cell Activation and Exacerbates NKT Cell Ligand-Induced Airway Hyperresponsiveness and Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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pConsensus Peptide Induces Tolerogenic CD8⁺ T Cells in Lupus-Prone (NZB × NZW)F₁ Mice by Differentially Regulating Foxp3 and PD1 Molecules ¹

Ram Pyare Singh; Antonio La Cava; Bevra H. Hahn

J Immunol (2008) 180 (4): 2069–2080.

View articletitled, pConsensus Peptide Induces Tolerogenic CD8<sup>+</sup> T Cells in Lupus-Prone (NZB × NZW)F<sub>1</sub> Mice by Differentially Regulating Foxp3 and PD1 Molecules<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Selective Regulation of CD8 Effector T Cell Migration by the p110γ Isoform of Phosphatidylinositol 3-Kinase ¹

Amanda L. Martin; Matthew D. Schwartz; Stephen C. Jameson; Yoji Shimizu

J Immunol (2008) 180 (4): 2081–2088.

View articletitled, Selective Regulation of CD8 Effector T Cell Migration by the p110γ Isoform of Phosphatidylinositol 3-Kinase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibition of STAT3 Promotes the Efficacy of Adoptive Transfer Therapy Using Type-1 CTLs by Modulation of the Immunological Microenvironment in a Murine Intracranial Glioma ¹

Mitsugu Fujita; Xinmei Zhu; Kotaro Sasaki; Ryo Ueda; Keri L. Low; Ian F. Pollack; Hideho Okada

J Immunol (2008) 180 (4): 2089–2098.

View articletitled, Inhibition of STAT3 Promotes the Efficacy of Adoptive Transfer Therapy Using Type-1 CTLs by Modulation of the Immunological Microenvironment in a Murine Intracranial Glioma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Preassociation of IL-15 with IL-15Rα-IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8⁺/CD44^high T Cells and Its Antitumor Action ¹

Sigrid Dubois; Hiral J. Patel; Meili Zhang; Thomas A. Waldmann; Jürgen R. Müller

J Immunol (2008) 180 (4): 2099–2106.

View articletitled, Preassociation of IL-15 with IL-15Rα-IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8<sup>+</sup>/CD44<sup>high</sup> T Cells and Its Antitumor Action<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Antigen Controls IL-7Rα Expression Levels on CD8 T Cells during Full Activation or Tolerance Induction ¹

Christopher D. Hammerbeck; Matthew F. Mescher

J Immunol (2008) 180 (4): 2107–2116.

View articletitled, Antigen Controls IL-7Rα Expression Levels on CD8 T Cells during Full Activation or Tolerance Induction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages ¹

Michael P. Gantier; Stephen Tong; Mark A. Behlke; Dakang Xu; Simon Phipps; Paul S. Foster; Bryan R. G. Williams

J Immunol (2008) 180 (4): 2117–2124.

View articletitled, TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Prostaglandin E₂ Suppresses Lipopolysaccharide-Stimulated IFN-β Production ¹

X. Julia Xu; Jonathan S. Reichner; Balduino Mastrofrancesco; William L. Henry, Jr.; Jorge E. Albina

J Immunol (2008) 180 (4): 2125–2131.

View articletitled, Prostaglandin E<sub>2</sub> Suppresses Lipopolysaccharide-Stimulated IFN-β Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Ex Vivo Generated Regulatory T Cells Modulate Experimental Autoimmune Myasthenia Gravis ¹

Revital Aricha; Tali Feferman; Sara Fuchs; Miriam C. Souroujon

J Immunol (2008) 180 (4): 2132–2139.

View articletitled, Ex Vivo Generated Regulatory T Cells Modulate Experimental Autoimmune Myasthenia Gravis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-12 Is Required for Anti-OX40-Mediated CD4 T Cell Survival

Carl E. Ruby; Ryan Montler; Rongxui Zheng; Suyu Shu; Andrew D. Weinberg

J Immunol (2008) 180 (4): 2140–2148.

View articletitled, IL-12 Is Required for Anti-OX40-Mediated CD4 T Cell Survival

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CD4⁺CD25⁺ Regulatory T Cell Repertoire Formation Shaped by Differential Presentation of Peptides from a Self-Antigen ¹

Joseph Larkin, III; Andrew L. Rankin; Cristina Cozzo Picca; Michael P. Riley; Scott A. Jenks; Andrea J. Sant; Andrew J. Caton

J Immunol (2008) 180 (4): 2149–2157.

View articletitled, CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cell Repertoire Formation Shaped by Differential Presentation of Peptides from a Self-Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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STAT1 Signaling in CD8 T Cells Is Required for Their Clonal Expansion and Memory Formation Following Viral Infection In Vivo ¹

Michael Quigley; Xiaopei Huang; Yiping Yang

J Immunol (2008) 180 (4): 2158–2164.

View articletitled, STAT1 Signaling in CD8 T Cells Is Required for Their Clonal Expansion and Memory Formation Following Viral Infection In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Magnitude of the Antibody and Memory B Cell Responses during Priming with a Protein-Polysaccharide Conjugate Vaccine in Human Infants Is Associated with the Persistence of Antibody and the Intensity of Booster Response ¹

Geraldine Blanchard Rohner; Matthew D. Snape; Dominic F. Kelly; Tessa John; Anita Morant; Ly-Mee Yu; Astrid Borkowski; Francesca Ceddia; Ray Borrow; Claire-Anne Siegrist; Andrew J. Pollard

J Immunol (2008) 180 (4): 2165–2173.

View articletitled, The Magnitude of the Antibody and Memory B Cell Responses during Priming with a Protein-Polysaccharide Conjugate Vaccine in Human Infants Is Associated with the Persistence of Antibody and the Intensity of Booster Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Induction of Broad Cross-Subtype-Specific HIV-1 Immune Responses by a Novel Multivalent HIV-1 Peptide Vaccine in Cynomolgus Macaques

Ali Azizi; David E. Anderson; José V. Torres; Andrei Ogrel; Masoud Ghorbani; Catalina Soare; Paul Sandstrom; Jocelyne Fournier; Francisco Diaz-Mitoma

J Immunol (2008) 180 (4): 2174–2186.

View articletitled, Induction of Broad Cross-Subtype-Specific HIV-1 Immune Responses by a Novel Multivalent HIV-1 Peptide Vaccine in Cynomolgus Macaques

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Bacterial Fimbriae Stimulate Proinflammatory Activation in the Endothelium through Distinct TLRs ¹

Michael Davey; Xinyan Liu; Takashi Ukai; Vishal Jain; Cynthia Gudino; Frank C. Gibson, III; Douglas Golenbock; Alberto Visintin; Caroline A. Genco

J Immunol (2008) 180 (4): 2187–2195.

View articletitled, Bacterial Fimbriae Stimulate Proinflammatory Activation in the Endothelium through Distinct TLRs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Molecular and Anatomical Basis for B Cell Migration into the Peritoneal Cavity and Omental Milky Spots ¹

Simon Berberich; Sabrina Dähne; Angela Schippers; Thorsten Peters; Werner Müller; Elisabeth Kremmer; Reinhold Förster; Oliver Pabst

J Immunol (2008) 180 (4): 2196–2203.

View articletitled, Differential Molecular and Anatomical Basis for B Cell Migration into the Peritoneal Cavity and Omental Milky Spots<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination: A New Role for Neurotrophic Cytokines in Neuroinflammation ¹

Ralf A. Linker; Niels Kruse; Stephanie Israel; Tao Wei; Silvia Seubert; Anja Hombach; Bettina Holtmann; Fred Luhder; Richard M. Ransohoff; Michael Sendtner; Ralf Gold

J Immunol (2008) 180 (4): 2204–2213.

View articletitled, Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination: A New Role for Neurotrophic Cytokines in Neuroinflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Anti-MHC Class I Antibody Activation of Proliferation and Survival Signaling in Murine Cardiac Allografts ¹

Peter T. Jindra; Aileen Hsueh; Longshen Hong; David Gjertson; Xiu-Da Shen; Feng Gao; Julie Dang; Paul S. Mischel; William M. Baldwin, III; Michael C. Fishbein; Jerzy W. Kupiec-Weglinski; Elaine F. Reed

J Immunol (2008) 180 (4): 2214–2224.

View articletitled, Anti-MHC Class I Antibody Activation of Proliferation and Survival Signaling in Murine Cardiac Allografts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Chlamydia muridarum Infection Subverts Dendritic Cell Function to Promote Th2 Immunity and Airways Hyperreactivity

Gerard E. Kaiko; Simon Phipps; Danica K. Hickey; Chuan En Lam; Philip M. Hansbro; Paul S. Foster; Kenneth W. Beagley

J Immunol (2008) 180 (4): 2225–2232.

View articletitled, <em>Chlamydia muridarum</em> Infection Subverts Dendritic Cell Function to Promote Th2 Immunity and Airways Hyperreactivity

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Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr²⁺ Entry, Optimal Influx of Ca²⁺, and Degranulation in a Rat Mast Cell Line ¹

Hong-Tao Ma; Ze Peng; Takaaki Hiragun; Shoko Iwaki; Alasdair M. Gilfillan; Michael A. Beaven

J Immunol (2008) 180 (4): 2233–2239.

View articletitled, Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr<sup>2+</sup> Entry, Optimal Influx of Ca<sup>2+</sup>, and Degranulation in a Rat Mast Cell Line<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Comprehensive Assessment and Mathematical Modeling of T Cell Population Dynamics and Homeostasis ¹

Véronique Thomas-Vaslin; Hester Korthals Altes; Rob J. de Boer; David Klatzmann

J Immunol (2008) 180 (4): 2240–2250.

View articletitled, Comprehensive Assessment and Mathematical Modeling of T Cell Population Dynamics and Homeostasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Agonists of the Mas-Related Gene (Mrgs) Orphan Receptors as Novel Mediators of Mast Cell-Sensory Nerve Interactions ¹

Min-Goo Lee; Xinzhong Dong; Qin Liu; Kush N. Patel; Oksoon Hong Choi; Becky Vonakis; Bradley J. Undem

J Immunol (2008) 180 (4): 2251–2255.

View articletitled, Agonists of the <em>Mas</em>-Related Gene (Mrgs) Orphan Receptors as Novel Mediators of Mast Cell-Sensory Nerve Interactions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Characterization of the In Vivo Dynamics of Medullary CD4⁺CD8⁻ Thymocyte Development ¹

Rong Jin; Wei Wang; Jin-Yan Yao; Yu-Bin Zhou; Xiao-Ping Qian; Jun Zhang; Yu Zhang; Wei-Feng Chen

J Immunol (2008) 180 (4): 2256–2263.

View articletitled, Characterization of the In Vivo Dynamics of Medullary CD4<sup>+</sup>CD8<sup>−</sup> Thymocyte Development<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Histone Methylation Patterns Are Cell-Type Specific in Human Monocytes and Lymphocytes and Well Maintained at Core Genes ¹

Feng Miao; Xiwei Wu; Lingxiao Zhang; Arthur D. Riggs; Rama Natarajan

J Immunol (2008) 180 (4): 2264–2269.

View articletitled, Histone Methylation Patterns Are Cell-Type Specific in Human Monocytes and Lymphocytes and Well Maintained at Core Genes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Maturing Dendritic Cells Depend on RAGE for In Vivo Homing to Lymph Nodes ¹

Angelo A. Manfredi; Annalisa Capobianco; Antonio Esposito; Francesco De Cobelli; Tamara Canu; Antonella Monno; Angela Raucci; Francesca Sanvito; Claudio Doglioni; Peter P. Nawroth; Angelika Bierhaus; Marco E. Bianchi; Patrizia Rovere-Querini; Alessandro Del Maschio

J Immunol (2008) 180 (4): 2270–2275.

View articletitled, Maturing Dendritic Cells Depend on RAGE for In Vivo Homing to Lymph Nodes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Critical Role of Costimulation during Intrathymic Development of Invariant NK T Cells ¹

Yeonseok Chung; Roza Nurieva; Eiji Esashi; Yi-Hong Wang; Dapeng Zhou; Laurent Gapin; Chen Dong

J Immunol (2008) 180 (4): 2276–2283.

View articletitled, A Critical Role of Costimulation during Intrathymic Development of Invariant NK T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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ICOS, CD40, and Lymphotoxin β Receptors Signal Sequentially and Interdependently to Initiate a Germinal Center Reaction ¹

Frances Vu; Umberto Dianzani; Carl F. Ware; Tak Mak; Jennifer L. Gommerman

J Immunol (2008) 180 (4): 2284–2293.

View articletitled, ICOS, CD40, and Lymphotoxin β Receptors Signal Sequentially and Interdependently to Initiate a Germinal Center Reaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complement Activation Plays a Key Role in Antibody-Induced Infusion Toxicity in Monkeys and Rats

Tomonori Tawara; Kazumasa Hasegawa; Yusuke Sugiura; Katsuhiko Harada; Toru Miura; Sunao Hayashi; Tomoyuki Tahara; Masaharu Ishikawa; Hideaki Yoshida; Kinya Kubo; Isao Ishida; Shiro Kataoka

J Immunol (2008) 180 (4): 2294–2298.

View articletitled, Complement Activation Plays a Key Role in Antibody-Induced Infusion Toxicity in Monkeys and Rats

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Why T Cells of Thymic Versus Extrathymic Origin Are Functionally Different ¹

Marie-Ève Blais; Sylvie Brochu; Martin Giroux; Marie-Pier Bélanger; Gaël Dulude; Rafick-Pierre Sékaly; Claude Perreault

J Immunol (2008) 180 (4): 2299–2312.

View articletitled, Why T Cells of Thymic Versus Extrathymic Origin Are Functionally Different<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Three-Dimensional Structure of the Cross-Reactive Pollen Allergen Che a 3: Visualizing Cross-Reactivity on the Molecular Surfaces of Weed, Grass, and Tree Pollen Allergens ¹

Petra Verdino; Rodrigo Barderas; Mayte Villalba; Kerstin Westritschnig; Rudolf Valenta; Rosalia Rodriguez; Walter Keller

J Immunol (2008) 180 (4): 2313–2321.

View articletitled, Three-Dimensional Structure of the Cross-Reactive Pollen Allergen Che a 3: Visualizing Cross-Reactivity on the Molecular Surfaces of Weed, Grass, and Tree Pollen Allergens<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Protective Effect of IL-18 on Kainate- and IL-1β-Induced Cerebellar Ataxia in Mice ¹

Tsugunobu Andoh; Hiroyuki Kishi; Kazumi Motoki; Kenji Nakanishi; Yasushi Kuraishi; Atsushi Muraguchi

J Immunol (2008) 180 (4): 2322–2328.

View articletitled, Protective Effect of IL-18 on Kainate- and IL-1β-Induced Cerebellar Ataxia in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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C1q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition ¹

Helena Païdassi; Pascale Tacnet-Delorme; Virginie Garlatti; Claudine Darnault; Berhane Ghebrehiwet; Christine Gaboriaud; Gérard J. Arlaud; Philippe Frachet

J Immunol (2008) 180 (4): 2329–2338.

View articletitled, C1q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Productive Coupling of Accessible Vβ14 Segments and DJβ Complexes Determines the Frequency of Vβ14 Rearrangement ¹

Sheila Ranganath; Andrea C. Carpenter; Megan Gleason; Albert C. Shaw; Craig H. Bassing; Frederick W. Alt

J Immunol (2008) 180 (4): 2339–2346.

View articletitled, Productive Coupling of Accessible Vβ14 Segments and DJβ Complexes Determines the Frequency of Vβ14 Rearrangement<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Porcine Reproductive and Respiratory Syndrome Virus Subverts Repertoire Development by Proliferation of Germline-Encoded B Cells of All Isotypes Bearing Hydrophobic Heavy Chain CDR3 ¹

John E. Butler; Nancy Wertz; Patrick Weber; Kelly M. Lager

J Immunol (2008) 180 (4): 2347–2356.

View articletitled, Porcine Reproductive and Respiratory Syndrome Virus Subverts Repertoire Development by Proliferation of Germline-Encoded B Cells of All Isotypes Bearing Hydrophobic Heavy Chain CDR3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HLA Class I Antibody-Mediated Endothelial Cell Proliferation via the mTOR Pathway ¹

Peter T. Jindra; Yi-Ping Jin; Enquire Rozengurt; Elaine F. Reed

J Immunol (2008) 180 (4): 2357–2366.

View articletitled, HLA Class I Antibody-Mediated Endothelial Cell Proliferation via the mTOR Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

Human Trophoblasts Recruited T Lymphocytes and Monocytes into Decidua by Secretion of Chemokine CXCL16 and Interaction with CXCR6 in the First-Trimester Pregnancy ¹

Yu Huang; Xiao-Yong Zhu; Mei-Rong Du; Da-Jin Li

J Immunol (2008) 180 (4): 2367–2375.

View articletitled, Human Trophoblasts Recruited T Lymphocytes and Monocytes into Decidua by Secretion of Chemokine CXCL16 and Interaction with CXCR6 in the First-Trimester Pregnancy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

IL-13 Is Required for Eosinophil Entry into the Lung during Respiratory Syncytial Virus Vaccine-Enhanced Disease ¹

Elaine M. Castilow; David K. Meyerholz; Steven M. Varga

J Immunol (2008) 180 (4): 2376–2384.

View articletitled, IL-13 Is Required for Eosinophil Entry into the Lung during Respiratory Syncytial Virus Vaccine-Enhanced Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Interferon-Induced Expression of MxA in the Respiratory Tract of Rhesus Macaques Is Suppressed by Influenza Virus Replication ¹

Timothy D. Carroll; Shannon R. Matzinger; Meritxell Genescà; Linda Fritts; Roxana Colòn; Michael B. McChesney; Christopher J. Miller

J Immunol (2008) 180 (4): 2385–2395.

View articletitled, Interferon-Induced Expression of MxA in the Respiratory Tract of Rhesus Macaques Is Suppressed by Influenza Virus Replication<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection ¹

Shibichakravarthy Kannan; Aaron Audet; Huang Huang; Li-juan Chen; Min Wu

J Immunol (2008) 180 (4): 2396–2408.

View articletitled, Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during <em>Pseudomonas aeruginosa</em> Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Pneumococcal Capsular Polysaccharide Is Immunogenic When Present on the Surface of Macrophages and Dendritic Cells: TLR4 Signaling Induced by a Conjugate Vaccine or by Lipopolysaccharide Is Conducive ¹

Noam Cohen; Michal Stolarsky-Bennun; Hila Amir-Kroll; Raanan Margalit; Gabriel Nussbaum; Michal Cohen-Sfady; Meirav Pevsner-Fischer; Mati Fridkin; Herve Bercovier; Lea Eisenbach; Steffen Jung; Irun R. Cohen

J Immunol (2008) 180 (4): 2409–2418.

View articletitled, Pneumococcal Capsular Polysaccharide Is Immunogenic When Present on the Surface of Macrophages and Dendritic Cells: TLR4 Signaling Induced by a Conjugate Vaccine or by Lipopolysaccharide Is Conducive<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Integrin β₁ Regulates Phagosome Maturation in Macrophages through Rac Expression ¹

Qing-Qing Wang; Hong Li; Tim Oliver; Michael Glogauer; Jian Guo; You-Wen He

J Immunol (2008) 180 (4): 2419–2428.

View articletitled, Integrin β<sub>1</sub> Regulates Phagosome Maturation in Macrophages through Rac Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A238L Inhibits NF-ATc2, NF-κB, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C-θ-Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p300 ¹

Aitor G. Granja; Neil D. Perkins; Yolanda Revilla

J Immunol (2008) 180 (4): 2429–2442.

View articletitled, A238L Inhibits NF-ATc2, NF-κB, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C-θ-Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p300<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes ¹

Neil E. Humphreys; Damo Xu; Matthew R. Hepworth; Foo Y. Liew; Richard K. Grencis

J Immunol (2008) 180 (4): 2443–2449.

View articletitled, IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Injury Enhances Resistance to Escherichia coli Infection by Boosting Innate Immune System Function ¹

Adrian A. Maung; Satoshi Fujimi; Malcolm P. MacConmara; Goro Tajima; Ann M. McKenna; Adam J. Delisle; Christopher Stallwood; Andrew B. Onderdonk; John A. Mannick; James A. Lederer

J Immunol (2008) 180 (4): 2450–2458.

View articletitled, Injury Enhances Resistance to <em>Escherichia coli</em> Infection by Boosting Innate Immune System Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunoproteomic Discovery of Novel T Cell Antigens from the Obligate Intracellular Pathogen Chlamydia¹

Karuna P. Karunakaran; Jose Rey-Ladino; Nikolay Stoynov; Kyra Berg; Caixia Shen; Xiaozhou Jiang; Brent R. Gabel; Hong Yu; Leonard J. Foster; Robert C. Brunham

J Immunol (2008) 180 (4): 2459–2465.

View articletitled, Immunoproteomic Discovery of Novel T Cell Antigens from the Obligate Intracellular Pathogen <em>Chlamydia</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Role of Galectin-3 in Leukocyte Recruitment in a Murine Model of Lung Infection by Streptococcus pneumoniae¹

Julie Nieminen; Christian St-Pierre; Pampa Bhaumik; Françoise Poirier; Sachiko Sato

J Immunol (2008) 180 (4): 2466–2473.

View articletitled, Role of Galectin-3 in Leukocyte Recruitment in a Murine Model of Lung Infection by <em>Streptococcus pneumoniae</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity ¹

Nina Ank; Marie B. Iversen; Christina Bartholdy; Peter Staeheli; Rune Hartmann; Uffe B. Jensen; Frederik Dagnaes-Hansen; Allan R. Thomsen; Zhi Chen; Harald Haugen; Kevin Klucher; Søren R. Paludan

J Immunol (2008) 180 (4): 2474–2485.

View articletitled, An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-23 Is Required for the Development of Severe Egg-Induced Immunopathology in Schistosomiasis and for Lesional Expression of IL-17 ¹

Laura I. Rutitzky; Lindsey Bazzone; Mara G. Shainheit; Barbara Joyce-Shaikh; Daniel J. Cua; Miguel J. Stadecker

J Immunol (2008) 180 (4): 2486–2495.

View articletitled, IL-23 Is Required for the Development of Severe Egg-Induced Immunopathology in Schistosomiasis and for Lesional Expression of IL-17<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells ¹

Hajime Hisaeda; Kohhei Tetsutani; Takashi Imai; Chikako Moriya; Liping Tu; Shinjiro Hamano; Xuefeng Duan; Bin Chou; Hidekazu Ishida; Akiko Aramaki; Jianying Shen; Ken J. Ishii; Cevayir Coban; Shizuo Akira; Kiyoshi Takeda; Koji Yasutomo; Motomi Torii; Kunisuke Himeno

J Immunol (2008) 180 (4): 2496–2503.

View articletitled, Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Novel Vaccination Protocol with Two Live Mucosal Vectors Elicits Strong Cell-Mediated Immunity in the Vagina and Protects against Vaginal Virus Challenge ¹

Zhongxia Li; Manxin Zhang; Chenghui Zhou; Xinyan Zhao; Norifumi Iijima; Fred R. Frankel

J Immunol (2008) 180 (4): 2504–2513.

View articletitled, Novel Vaccination Protocol with Two Live Mucosal Vectors Elicits Strong Cell-Mediated Immunity in the Vagina and Protects against Vaginal Virus Challenge<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulatory T Cells Prevent Control of Experimental African Trypanosomiasis ¹

Guojian Wei; Henry Tabel

J Immunol (2008) 180 (4): 2514–2521.

View articletitled, Regulatory T Cells Prevent Control of Experimental African Trypanosomiasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

Auto-Oxidation and Oligomerization of Protein S on the Apoptotic Cell Surface Is Required for Mer Tyrosine Kinase-Mediated Phagocytosis of Apoptotic Cells

Hiroshi Uehara; Emily Shacter

J Immunol (2008) 180 (4): 2522–2530.

View articletitled, Auto-Oxidation and Oligomerization of Protein S on the Apoptotic Cell Surface Is Required for Mer Tyrosine Kinase-Mediated Phagocytosis of Apoptotic Cells

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HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines ¹

Yonggang Sha; Jaroslaw Zmijewski; Zhiwei Xu; Edward Abraham

J Immunol (2008) 180 (4): 2531–2537.

View articletitled, HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110δ but Not p110γ Promotes Optimal Allergic Responses In Vivo ¹

Khaled Ali; Montserrat Camps; Wayne P. Pearce; Hong Ji; Thomas Rückle; Nicolas Kuehn; Christian Pasquali; Christian Chabert; Christian Rommel; Bart Vanhaesebroeck

J Immunol (2008) 180 (4): 2538–2544.

View articletitled, Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110δ but Not p110γ Promotes Optimal Allergic Responses In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tristetraprolin Regulates CXCL1 (KC) mRNA Stability ¹

Shyamasree Datta; Roopa Biswas; Michael Novotny; Paul G. Pavicic, Jr.; Tomasz Herjan; Palash Mandal; Thomas A. Hamilton

J Immunol (2008) 180 (4): 2545–2552.

View articletitled, Tristetraprolin Regulates CXCL1 (KC) mRNA Stability<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lipoteichoic Acid Isolated from Lactobacillus plantarum Inhibits Lipopolysaccharide-Induced TNF-α Production in THP-1 Cells and Endotoxin Shock in Mice ¹

Han Geun Kim; Na-Ra Kim; Min Geun Gim; Jung Min Lee; Seung Yeon Lee; Mi Yeon Ko; Joo Yun Kim; Seung Hyun Han; Dae Kyun Chung

J Immunol (2008) 180 (4): 2553–2561.

View articletitled, Lipoteichoic Acid Isolated from <em>Lactobacillus plantarum</em> Inhibits Lipopolysaccharide-Induced TNF-α Production in THP-1 Cells and Endotoxin Shock in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CCR2⁺ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality ¹

Kaifeng Lisa Lin; Yasushi Suzuki; Hideki Nakano; Elizabeth Ramsburg; Michael Dee Gunn

J Immunol (2008) 180 (4): 2562–2572.

View articletitled, CCR2<sup>+</sup> Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A CD8⁺/CD103^high T Cell Subset Regulates TNF-Mediated Chronic Murine Ileitis ¹

Johnson Ho; Courtney C. Kurtz; Makoto Naganuma; Peter B. Ernst; Fabio Cominelli; Jesús Rivera-Nieves

J Immunol (2008) 180 (4): 2573–2580.

View articletitled, A CD8<sup>+</sup>/CD103<sup>high</sup> T Cell Subset Regulates TNF-Mediated Chronic Murine Ileitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type ¹

Mikako Sasaki; Riichiro Abe; Yasuyuki Fujita; Satomi Ando; Daisuke Inokuma; Hiroshi Shimizu

J Immunol (2008) 180 (4): 2581–2587.

View articletitled, Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Loss of Epithelial RelA Results in Deregulated Intestinal Proliferative/Apoptotic Homeostasis and Susceptibility to Inflammation ¹

Kris A. Steinbrecher; Eleana Harmel-Laws; Raquel Sitcheran; Albert S. Baldwin

J Immunol (2008) 180 (4): 2588–2599.

View articletitled, Loss of Epithelial RelA Results in Deregulated Intestinal Proliferative/Apoptotic Homeostasis and Susceptibility to Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Granulocyte-Macrophage Colony-Stimulating Factor Is Required for Bronchial Eosinophilia in a Murine Model of Allergic Airway Inflammation ¹

Yung-Chang Su; Michael S. Rolph; Nicole G. Hansbro; Charles R. Mackay; William A. Sewell

J Immunol (2008) 180 (4): 2600–2607.

View articletitled, Granulocyte-Macrophage Colony-Stimulating Factor Is Required for Bronchial Eosinophilia in a Murine Model of Allergic Airway Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Plant-Derived Ligand Favoring Monomeric Glucocorticoid Receptor Conformation with Impaired Transactivation Potential Attenuates Collagen-Induced Arthritis ¹

Pieter Dewint; Valerie Gossye; Karolien De Bosscher; Wim Vanden Berghe; Katrien Van Beneden; Dieter Deforce; Serge Van Calenbergh; Ulf Müller-Ladner; Bert Vander Cruyssen; Gust Verbruggen; Guy Haegeman; Dirk Elewaut

J Immunol (2008) 180 (4): 2608–2615.

View articletitled, A Plant-Derived Ligand Favoring Monomeric Glucocorticoid Receptor Conformation with Impaired Transactivation Potential Attenuates Collagen-Induced Arthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Transglutaminase Type II Is Involved in the Pathogenesis of Endotoxic Shock ¹

Laura Falasca; Maria Grazia Farrace; Alessandra Rinaldi; Loretta Tuosto; Gennard Melino; Mauro Piacentini

J Immunol (2008) 180 (4): 2616–2624.

View articletitled, Transglutaminase Type II Is Involved in the Pathogenesis of Endotoxic Shock<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD44 Is Critically Involved in Infarct Healing by Regulating the Inflammatory and Fibrotic Response ¹

Peter Huebener; Tareq Abou-Khamis; Pawel Zymek; Marcin Bujak; Xia Ying; Khaled Chatila; Sandra Haudek; Geeta Thakker; Nikolaos G. Frangogiannis

J Immunol (2008) 180 (4): 2625–2633.

View articletitled, CD44 Is Critically Involved in Infarct Healing by Regulating the Inflammatory and Fibrotic Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Notch3 Inhibition in Myelin-Reactive T Cells Down-Regulates Protein Kinase Cθ and Attenuates Experimental Autoimmune Encephalomyelitis ¹

Maciej Jurynczyk; Anna Jurewicz; Cedric S. Raine; Krzysztof Selmaj

J Immunol (2008) 180 (4): 2634–2640.

View articletitled, Notch3 Inhibition in Myelin-Reactive T Cells Down-Regulates Protein Kinase Cθ and Attenuates Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CXCR3 Mediates Region-Specific Antiviral T Cell Trafficking within the Central Nervous System during West Nile Virus Encephalitis ¹

Bo Zhang; Ying Kai Chan; Bao Lu; Michael S. Diamond; Robyn S. Klein

J Immunol (2008) 180 (4): 2641–2649.

View articletitled, CXCR3 Mediates Region-Specific Antiviral T Cell Trafficking within the Central Nervous System during West Nile Virus Encephalitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Alternative Macrophage Activation by Galectin-3 ¹

Alison C. MacKinnon; Sarah L. Farnworth; Philip S. Hodkinson; Neil C. Henderson; Kirsten M. Atkinson; Hakon Leffler; Ulf J. Nilsson; Christopher Haslett; Stuart J. Forbes; Tariq Sethi

J Immunol (2008) 180 (4): 2650–2658.

View articletitled, Regulation of Alternative Macrophage Activation by Galectin-3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Intestinal Inflammation Increases the Expression of the P2Y₆ Receptor on Epithelial Cells and the Release of CXC Chemokine Ligand 8 by UDP ¹

Djordje M. Grbic; Émilie Degagné; Christine Langlois; Andrée-Anne Dupuis; Fernand-Pierre Gendron

J Immunol (2008) 180 (4): 2659–2668.

View articletitled, Intestinal Inflammation Increases the Expression of the P2Y<sub>6</sub> Receptor on Epithelial Cells and the Release of CXC Chemokine Ligand 8 by UDP<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibitory ITAM Signaling by FcαRI-FcRγ Chain Controls Multiple Activating Responses and Prevents Renal Inflammation ¹

Yutaka Kanamaru; Séverine Pfirsch; Meryem Aloulou; François Vrtovsnik; Marie Essig; Chantal Loirat; Georges Deschênes; Claudine Guérin-Marchand; Ulrich Blank; Renato C. Monteiro

J Immunol (2008) 180 (4): 2669–2678.

View articletitled, Inhibitory ITAM Signaling by FcαRI-FcRγ Chain Controls Multiple Activating Responses and Prevents Renal Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

IL-13-Mediated Gender Difference in Susceptibility to Autoimmune Encephalomyelitis ¹

Sushmita Sinha; Laurie J. Kaler; Thomas M. Proctor; Cory Teuscher; Arthur A. Vandenbark; Halina Offner

J Immunol (2008) 180 (4): 2679–2685.

View articletitled, IL-13-Mediated Gender Difference in Susceptibility to Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD11b⁺ Monocytes Abrogate Th17 CD4⁺ T Cell-Mediated Experimental Autoimmune Myocarditis ¹

Alan Valaperti; René R. Marty; Gabriela Kania; Davide Germano; Nora Mauermann; Stefan Dirnhofer; Bernd Leimenstoll; Przemyslaw Blyszczuk; Chen Dong; Christian Mueller; Lukas Hunziker; Urs Eriksson

J Immunol (2008) 180 (4): 2686–2695.

View articletitled, CD11b<sup>+</sup> Monocytes Abrogate Th17 CD4<sup>+</sup> T Cell-Mediated Experimental Autoimmune Myocarditis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Pixantrone (BBR2778) Reduces the Severity of Experimental Autoimmune Myasthenia Gravis in Lewis Rats ¹

Federica Ubiali; Sara Nava; Valeria Nessi; Renato Longhi; Gabriella Pezzoni; Raffaella Capobianco; Renato Mantegazza; Carlo Antozzi; Fulvio Baggi

J Immunol (2008) 180 (4): 2696–2703.

View articletitled, Pixantrone (BBR2778) Reduces the Severity of Experimental Autoimmune Myasthenia Gravis in Lewis Rats<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Up-Regulation of Programmed Death-1 Expression on Beryllium-Specific CD4⁺ T Cells in Chronic Beryllium Disease ¹

Brent E. Palmer; Douglas G. Mack; Allison K. Martin; May Gillespie; Margaret M. Mroz; Lisa A. Maier; Andrew P. Fontenot

J Immunol (2008) 180 (4): 2704–2712.

View articletitled, Up-Regulation of Programmed Death-1 Expression on Beryllium-Specific CD4<sup>+</sup> T Cells in Chronic Beryllium Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cover Image

Cover Image

On the cover: Mouse omenta were stained as whole mounts using anti-B220 (blue), anti-CD31 (green), and anti-MECA-79 (red) Abs and analyzed using confocal microscopy. Vessels within milky spots show MECA-79 reactivity, which overlaps with MAdCAM-1 expression, enabling B cell entry into the omentum. Berberich, S., S. Dähne, A. Schippers, T. Peters, W. Muller, E. Kremmer, R. Förster, and O. Pabst. 2008. Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J. Immunol. 180: 2196–2203.
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