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J Immunol (2008) 180 (5): 2721–2722.

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PILLARS OF IMMUNOLOGY

Antigen Presentation: Discovery of the Peptide TAP

Luc Van Kaer

J Immunol (2008) 180 (5): 2723–2724.

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Pillars Article: Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing. Science 1990. 250: 1723–1726.

John J. Monaco; Sungae Cho; Michelle Attaya

J Immunol (2008) 180 (5): 2725–2728.

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Pillars Article: MHC Class II Region Encoding Proteins Related to the Multidrug Resistance Family of Transmembrane Transporters. Nature 1990. 348: 738–741.

Edward V. Deverson; Irene R. Gow; W. John Coadwell; John J. Monaco; Geoffrey W. Butcher; Jonathan C. Howard

J Immunol (2008) 180 (5): 2729–2732.

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Pillars Article: Sequences Encoded in the Class II Region of the MHC Related to the ’ABC’ Superfamily of Transporters. Nature 1990. 348: 741–744.

John Trowsdale; Isabel Hanson; Ian Mockridge; Stephan Beck; Alain Townsend; Adrian Kelly

J Immunol (2008) 180 (5): 2733–2736.

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Pillars Article: A Gene in the Human Major Histocompatibility Complex Class II Region Controlling the Class I Antigen Presentation Pathway. Nature 1990. 348: 744–747.

Thomas Spies; Maureen Bresnahan; Seiamak Bahram; Daniele Arnold; George Blanck; Elizabeth Mellins; Donald Pious; Robert DeMars

J Immunol (2008) 180 (5): 2737–2740.

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BRIEF REVIEWS

Mechanisms for Decreased Function of B Cells in Aged Mice and Humans ¹

Daniela Frasca; Ana Marie Landin; Richard L. Riley; Bonnie B. Blomberg

J Immunol (2008) 180 (5): 2741–2746.

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CUTTING EDGE

Cutting Edge: TNFR-Shedding by CD4⁺CD25⁺ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators ¹

Geertje J. D. van Mierlo; Hans U. Scherer; Marjolijn Hameetman; Mary E. Morgan; Roelof Flierman; Tom W. J. Huizinga; René E. M. Toes

J Immunol (2008) 180 (5): 2747–2751.

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Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T Cells

Marcel Batten; Noelyn M. Kljavin; Ji Li; Michael J. Walter; Frederic J. de Sauvage; Nico Ghilardi

J Immunol (2008) 180 (5): 2752–2756.

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Cutting Edge: TGF-β-Induced Expression of Foxp3 in T cells Is Mediated through Inactivation of ERK

Xunrong Luo; Qiang Zhang; Victoria Liu; Zhenbiao Xia; Kathryn L. Pothoven; Chung Lee

J Immunol (2008) 180 (5): 2757–2761.

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Cutting Edge: Contributions of Apoptosis and Anergy to Systemic T Cell Tolerance ¹

Luke Barron; Birgit Knoechel; Jens Lohr; Abul K. Abbas

J Immunol (2008) 180 (5): 2762–2766.

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Cutting Edge: Selective Expression of Inhibitory or Activating Killer Cell Ig-Like Receptors in Circulating CD4⁺ T Lymphocytes ¹

Natacha Remtoula; Armand Bensussan; Anne Marie-Cardine

J Immunol (2008) 180 (5): 2767–2771.

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Cutting Edge: Vasoactive Intestinal Peptide (VIP) Induces Differentiation of Th17 Cells with a Distinctive Cytokine Profile ¹

Mahesh Yadav; Jennifer Rosenbaum; Edward J. Goetzl

J Immunol (2008) 180 (5): 2772–2776.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

β-Glucan Activates Microglia without Inducing Cytokine Production in Dectin-1-Dependent Manner

Vaibhav B. Shah; Yongcheng Huang; Rohan Keshwara; Tammy Ozment-Skelton; David L. Williams; Lakhu Keshvara

J Immunol (2008) 180 (5): 2777–2785.

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1,25-Dihydroxyvitamin D₃ Induces CCR10 Expression in Terminally Differentiating Human B Cells ¹

Aiko-Konno Shirakawa; Daisuke Nagakubo; Kunio Hieshima; Takashi Nakayama; Zhe Jin; Osamu Yoshie

J Immunol (2008) 180 (5): 2786–2795.

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Notch1 Signaling and Regulatory T Cell Function

Naoki Asano; Tomohiro Watanabe; Atsushi Kitani; Ivan J. Fuss; Warren Strober

J Immunol (2008) 180 (5): 2796–2804.

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Polyclonal MHC Ib-Restricted CD8⁺ T Cells Undergo Homeostatic Expansion in the Absence of Conventional MHC-Restricted T Cells ¹

David C. Jay; Lisa M. Reed-Loisel; Peter E. Jensen

J Immunol (2008) 180 (5): 2805–2814.

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RhoA Is Involved in LFA-1 Extension Triggered by CXCL12 but Not in a Novel Outside-In LFA-1 Activation Facilitated by CXCL9 ¹

Ronit Pasvolsky; Valentin Grabovsky; Cinzia Giagulli; Ziv Shulman; Revital Shamri; Sara W. Feigelson; Carlo Laudanna; Ronen Alon

J Immunol (2008) 180 (5): 2815–2823.

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Critical Synergy of CD30 and OX40 Signals in CD4 T Cell Homeostasis and Th1 Immunity to Salmonella¹

Fabrina Gaspal; Vasileios Bekiaris; Mi-Yeon Kim; David R. Withers; Saeeda Bobat; Ian C. M. MacLennan; Graham Anderson; Peter J. Lane; Adam F. Cunningham

J Immunol (2008) 180 (5): 2824–2829.

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Mitigation of Experimental Allergic Encephalomyelitis by TGF-β Induced Foxp3⁺ Regulatory T Lymphocytes through the Induction of Anergy and Infectious Tolerance ¹

Ramesh K. Selvaraj; Terrence L. Geiger

J Immunol (2008) 180 (5): 2830–2838.

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Heparan Sulfate and Heparin Enhance ERK Phosphorylation and Mediate preBCR-Dependent Events during B Lymphopoiesis ¹

Craig D. Milne; Steven A. Corfe; Christopher J. Paige

J Immunol (2008) 180 (5): 2839–2847.

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IL-10 Suppresses Mast Cell IgE Receptor Expression and Signaling In Vitro and In Vivo ¹

Sarah Kennedy Norton; Brian Barnstein; Jennifer Brenzovich; Daniel P. Bailey; Mohit Kashyap; Kelly Speiran; Jill Ford; Daniel Conrad; Stephanie Watowich; Matthew R. Moralle; Christopher L. Kepley; Peter J. Murray; John J. Ryan

J Immunol (2008) 180 (5): 2848–2854.

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Constitutive Expression of IL-7 Receptor α Does Not Support Increased Expansion or Prevent Contraction of Antigen-Specific CD4 or CD8 T Cells following Listeria monocytogenes Infection ¹

Jodie S. Haring; Xuefang Jing; Julie Bollenbacher-Reilley; Hai-Hui Xue; Warren J. Leonard; John T. Harty

J Immunol (2008) 180 (5): 2855–2862.

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B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice despite Isotype-Specific Differences in FcγR Effector Functions ¹

Yan Xiu; Carmen P. Wong; Jean-David Bouaziz; Yasuhito Hamaguchi; Yaming Wang; Shannon M. Pop; Roland M. Tisch; Thomas F. Tedder

J Immunol (2008) 180 (5): 2863–2875.

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Lysosomal Cysteine and Aspartic Proteases Are Heterogeneously Expressed and Act Redundantly to Initiate Human Invariant Chain Degradation ¹

Cristina M. Costantino; Howard C. Hang; Sally C. Kent; David A. Hafler; Hidde L. Ploegh

J Immunol (2008) 180 (5): 2876–2885.

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The Role for Monocyte Chemoattractant Protein-1 in the Generation and Function of Memory CD8⁺ T Cells ¹

Tao Wang; Hehua Dai; Ni Wan; Yolonda Moore; Zhenhua Dai

J Immunol (2008) 180 (5): 2886–2893.

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AIMP1/p43 Protein Induces the Maturation of Bone Marrow-Derived Dendritic Cells with T Helper Type 1-Polarizing Ability ¹

Eugene Kim; Seung Hyun Kim; Sunghoon Kim; Daeho Cho; Tae Sung Kim

J Immunol (2008) 180 (5): 2894–2902.

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STAT3 Is Indispensable to IL-27-Mediated Cell Proliferation but Not to IL-27-Induced Th1 Differentiation and Suppression of Proinflammatory Cytokine Production ¹

Toshiyuki Owaki; Masayuki Asakawa; Noriko Morishima; Izuru Mizoguchi; Fumio Fukai; Kiyoshi Takeda; Junichiro Mizuguchi; Takayuki Yoshimoto

J Immunol (2008) 180 (5): 2903–2911.

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Late Signals from CD27 Prevent Fas-Dependent Apoptosis of Primary CD8⁺ T Cells ¹

Douglas V. Dolfi; Alina C. Boesteanu; Constantinos Petrovas; Dong Xia; Eric A. Butz; Peter D. Katsikis

J Immunol (2008) 180 (5): 2912–2921.

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KIR2DL4 Differentially Signals Downstream Functions in Human NK Cells through Distinct Structural Modules ¹

S. M. Shahjahan Miah; Tracey L. Hughes; Kerry S. Campbell

J Immunol (2008) 180 (5): 2922–2932.

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Mutation in the Fas Pathway Impairs CD8⁺ T Cell Memory ¹

Renu Dudani; Marsha Russell; Henk van Faassen; Lakshmi Krishnan; Subash Sad

J Immunol (2008) 180 (5): 2933–2941.

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Involvement of Secretory and Endosomal Compartments in Presentation of an Exogenous Self-Glycolipid to Type II NKT Cells ¹

Keshab Chandra Roy; Igor Maricic; Archana Khurana; Trevor R. F. Smith; Ramesh C. Halder; Vipin Kumar

J Immunol (2008) 180 (5): 2942–2950.

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Splenic Stromal Microenvironment Negatively Regulates Virus-Activated Plasmacytoid Dendritic Cells through TGF-β ¹

Li Li; Shuxun Liu; Ting Zhang; Wei Pan; Xiao Yang; Xuetao Cao

J Immunol (2008) 180 (5): 2951–2956.

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Proliferative Expansion and Acquisition of Effector Activity by Memory CD4⁺ T Cells in the Lungs following Pulmonary Virus Infection ¹

Erika L. Wissinger; Whitney W. Stevens; Steven M. Varga; Thomas J. Braciale

J Immunol (2008) 180 (5): 2957–2966.

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Expression of ICOS on Human Melanoma-Infiltrating CD4⁺CD25^highFoxp3⁺ T Regulatory Cells: Implications and Impact on Tumor-Mediated Immune Suppression ¹

Laura Strauss; Christoph Bergmann; Miroslaw J. Szczepanski; Stephan Lang; John M. Kirkwood; Theresa L. Whiteside

J Immunol (2008) 180 (5): 2967–2980.

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Regulatory and Conventional CD4⁺ T Cells Show Differential Effects Correlating with PD-1 and B7-H1 Expression after Immunotherapy ¹^²

Kory L. Alderson; Qing Zhou; Vanessa Berner; Danice E. C. Wilkins; Jonathan M. Weiss; Bruce R. Blazar; Lisbeth A. Welniak; Robert H. Wiltrout; Doug Redelman; William J. Murphy

J Immunol (2008) 180 (5): 2981–2988.

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Interactions of T Cells with Fibroblast-Like Synoviocytes: Role of the B7 Family Costimulatory Ligand B7-H3 ¹

Chinh N. Tran; Seth G. Thacker; Deanna M. Louie; Jennifer Oliver; Peter T. White; Judith L. Endres; Andrew G. Urquhart; Kevin C. Chung; David A. Fox

J Immunol (2008) 180 (5): 2989–2998.

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Rat CD4⁺CD8⁺ Macrophages Kill Tumor Cells through an NKG2D- and Granzyme/Perforin-Dependent Mechanism ¹

Tomohisa Baba; Sari Iwasaki; Takako Maruoka; Akira Suzuki; Utano Tomaru; Hitoshi Ikeda; Takashi Yoshiki; Masanori Kasahara; Akihiro Ishizu

J Immunol (2008) 180 (5): 2999–3006.

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The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival ¹

Martin Felices; Leslie J. Berg

J Immunol (2008) 180 (5): 3007–3018.

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Blood Monocyte Subsets Differentially Give Rise to CD103⁺ and CD103⁻ Pulmonary Dendritic Cell Populations ¹

Claudia Jakubzick; Frank Tacke; Florent Ginhoux; Amy J. Wagers; Nico van Rooijen; Matthias Mack; Miriam Merad; Gwendalyn J. Randolph

J Immunol (2008) 180 (5): 3019–3027.

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Alternatively Activated Macrophages Regulate Extracellular Levels of the Hormone Placental Lactogen via Receptor-Mediated Uptake and Transcytosis ¹

Julia Kzhyshkowska; Alexei Gratchev; Christina Schmuttermaier; Heike Brundiers; Liis Krusell; Srinivas Mamidi; Jingjing Zhang; Gail Workman; E. Helene Sage; Christine Anderle; Peter Sedlmayr; Sergij Goerdt

J Immunol (2008) 180 (5): 3028–3037.

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Prophylactic Treatment with Fms-Like Tyrosine Kinase-3 Ligand after Burn Injury Enhances Global Immune Responses to Infection ¹

Julia Bohannon; Weihua Cui; Robert Cox; Rene Przkora; Edward Sherwood; Tracy Toliver-Kinsky

J Immunol (2008) 180 (5): 3038–3048.

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CCR5-Dependent Regulatory T Cell Migration Mediates Fungal Survival and Severe Immunosuppression ¹

Ana Paula Moreira; Karen Angelica Cavassani; Fabrine Sales Massafera Tristão; Ana Paula Campanelli; Roberto Martinez; Marcos Antonio Rossi; João S. Silva

J Immunol (2008) 180 (5): 3049–3056.

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Dermal Dendritic Cells, and Not Langerhans Cells, Play an Essential Role in Inducing an Immune Response ¹

Atsushi Fukunaga; Noor M. Khaskhely; Coimbatore S. Sreevidya; Scott N. Byrne; Stephen E. Ullrich

J Immunol (2008) 180 (5): 3057–3064.

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Phenotypic and Functional Characterization of Ultraviolet Radiation-Induced Regulatory T Cells ¹

Akira Maeda; Stefan Beissert; Thomas Schwarz; Agatha Schwarz

J Immunol (2008) 180 (5): 3065–3071.

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The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Down-Regulation ¹

Liying Wang; Neelam Azad; Lalana Kongkaneramit; Fei Chen; Yongju Lu; Bing-Hua Jiang; Yon Rojanasakul

J Immunol (2008) 180 (5): 3072–3080.

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Exosomes As a Short-Range Mechanism to Spread Alloantigen between Dendritic Cells during T Cell Allorecognition ¹

Angela Montecalvo; William J. Shufesky; Donna Beer Stolz; Mara G. Sullivan; Zhiliang Wang; Sherrie J. Divito; Glenn D. Papworth; Simon C. Watkins; Paul D. Robbins; Adriana T. Larregina; Adrian E. Morelli

J Immunol (2008) 180 (5): 3081–3090.

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Differential Roles of Galectin-1 and Galectin-3 in Regulating Leukocyte Viability and Cytokine Secretion ¹

Sean R. Stowell; Yuning Qian; Sougata Karmakar; Natalia S. Koyama; Marcelo Dias-Baruffi; Hakon Leffler; Rodger P. McEver; Richard D. Cummings

J Immunol (2008) 180 (5): 3091–3102.

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Spontaneous Renal Allograft Acceptance Associated with “Regulatory” Dendritic Cells and IDO ¹

Charles H. Cook; Alice A. Bickerstaff; Jiao-Jing Wang; Tibor Nadasdy; Patricia Della Pelle; Robert B. Colvin; Charles G. Orosz

J Immunol (2008) 180 (5): 3103–3112.

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Absence of CTL Responses to Early Viral Antigens Facilitates Viral Persistence ¹

Anita Schildknecht; Sarah Welti; Markus B. Geuking; Lars Hangartner; Maries van den Broek

J Immunol (2008) 180 (5): 3113–3121.

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Tumor-Specific CD4⁺ T Cells Render the Tumor Environment Permissive for Infiltration by Low-Avidity CD8⁺ T Cells ¹

S. B. Justin Wong; Rinke Bos; Linda A. Sherman

J Immunol (2008) 180 (5): 3122–3131.

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Radiation-Induced IFN-γ Production within the Tumor Microenvironment Influences Antitumor Immunity ¹

Amit A. Lugade; Elizabeth W. Sorensen; Scott A. Gerber; James P. Moran; John G. Frelinger; Edith M. Lord

J Immunol (2008) 180 (5): 3132–3139.

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ICOS Mediates the Development of Insulin-Dependent Diabetes Mellitus in Nonobese Diabetic Mice ¹

Daniel Hawiger; Elise Tran; Wei Du; Carmen J. Booth; Li Wen; Chen Dong; Richard A. Flavell

J Immunol (2008) 180 (5): 3140–3147.

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Vesicle-Associated Membrane Protein-8/Endobrevin Negatively Regulates Phagocytosis of Bacteria in Dendritic Cells ¹

Yong Hou Sunny Ho; Deyu Tarika Cai; Cheng-Chun Wang; Dachuan Huang; Siew Heng Wong

J Immunol (2008) 180 (5): 3148–3157.

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Knockdown of Mgat5 Inhibits Breast Cancer Cell Growth with Activation of CD4⁺ T Cells and Macrophages ¹

Dongqing Li; Yanmei Li; Xianglei Wu; Qiao Li; Jing Yu; Jie Gen; Xiao-Lian Zhang

J Immunol (2008) 180 (5): 3158–3165.

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Abnormal NF-κB Function Characterizes Human Type 1 Diabetes Dendritic Cells and Monocytes ¹

Zia U. A. Mollah; Saparna Pai; Craig Moore; Brendan J. O’Sullivan; Matthew J. Harrison; Judy Peng; Karen Phillips; Johannes B. Prins; John Cardinal; Ranjeny Thomas

J Immunol (2008) 180 (5): 3166–3175.

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Phylogenetic Conservation of Glycoprotein 96 Ability to Interact with CD91 and Facilitate Antigen Cross-Presentation ¹

Jacques Robert; Thaminda Ramanayake; Gregory D. Maniero; Heidi Morales; Asiya S. Chida

J Immunol (2008) 180 (5): 3176–3182.

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Contribution of Neural Crest-Derived Cells in the Embryonic and Adult Thymus ¹

Katie Foster; Julie Sheridan; Henrique Veiga-Fernandes; Kathleen Roderick; Vassilis Pachnis; Ralf Adams; Clare Blackburn; Dimitris Kioussis; Mark Coles

J Immunol (2008) 180 (5): 3183–3189.

Supplementary data

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Expansion of Effector Memory TCR Vβ4⁺CD8⁺ T Cells Is Associated with Latent Infection-Mediated Resistance to Transplantation Tolerance ¹

Dale Stapler; Eun D. Lee; Saranya A. Selvaraj; Andrew G. Evans; Leslie S. Kean; Samuel H. Speck; Christian P. Larsen; Shivaprakash Gangappa

J Immunol (2008) 180 (5): 3190–3200.

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Selection of an Antibody Library Identifies a Pathway to Induce Immunity by Targeting CD36 on Steady-State CD8α⁺ Dendritic Cells ¹

Elisa Tagliani; Pierre Guermonprez; Jorge Sepúlveda; María López-Bravo; Carlos Ardavín; Sebastian Amigorena; Federica Benvenuti; Oscar R. Burrone

J Immunol (2008) 180 (5): 3201–3209.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Characterizing the N-Terminal Processing Motif of MHC Class I Ligands ¹

Mark M. Schatz; Björn Peters; Nadja Akkad; Nina Ullrich; Alejandra Nacarino Martinez; Oliver Carroll; Sascha Bulik; Hans-Georg Rammensee; Peter van Endert; Hermann-Georg Holzhütter; Stefan Tenzer; Hansjörg Schild

J Immunol (2008) 180 (5): 3210–3217.

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Differential Activation of Dual Promoters Alters Dβ2 Germline Transcription during Thymocyte Development ¹

Ruth E. McMillan; Michael L. Sikes

J Immunol (2008) 180 (5): 3218–3228.

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Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference ¹

Florian Eberle; Kerstin Gießler; Christopher Deck; Klaus Heeg; Mirjam Peter; Clemens Richert; Alexander H. Dalpke

J Immunol (2008) 180 (5): 3229–3237.

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The Tumor Suppressor Death-Associated Protein Kinase Targets to TCR-Stimulated NF-κB Activation ¹

Ya-Ting Chuang; Li-Wen Fang; Ming-Hsien Lin-Feng; Ruey-Hwa Chen; Ming-Zong Lai

J Immunol (2008) 180 (5): 3238–3249.

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IMMUNOGENETICS

Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8⁺ T Cells in Nonobese Diabetic Mice ¹

David V. Serreze; Caroline Morgane Choisy-Rossi; Alexandra E. Grier; T. Mathew Holl; Harold D. Chapman; J. Reed Gahagan; Melissa A. Osborne; Weidong Zhang; Benjamin L. King; Aaron Brown; Derry Roopenian; Michele P. Marron

J Immunol (2008) 180 (5): 3250–3259.

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Regulation of the NK Cell Alloreactivity to Bone Marrow Cells by the Combination of the Host NK Gene Complex and MHC Haplotypes ¹

Koho Iizuka; Anthony A. Scalzo; Hong Xian; Wayne M. Yokoyama

J Immunol (2008) 180 (5): 3260–3267.

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Large-Scale Characterization of Natural Ligands Explains the Unique Gluten-Binding Properties of HLA-DQ2 ¹

Dariusz Stepniak; Martina Wiesner; Arnoud H. de Ru; Antonis K. Moustakas; Jan Wouter Drijfhout; George K. Papadopoulos; Peter A. van Veelen; Frits Koning

J Immunol (2008) 180 (5): 3268–3278.

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Immunodominance of the V_H1–46 Antibody Gene Segment in the Primary Repertoire of Human Rotavirus-Specific B Cells Is Reduced in the Memory Compartment through Somatic Mutation of Nondominant Clones ¹

Cuixia Tian; Grace K. Luskin; Kevin M. Dischert; James N. Higginbotham; Bryan E. Shepherd; James E. Crowe, Jr

J Immunol (2008) 180 (5): 3279–3288.

Supplementary data

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Vra4 Congenic Rats with Allelic Differences in the Class II Transactivator Gene Display Altered Susceptibility to Experimental Autoimmune Encephalomyelitis ¹

Karin Harnesk; Maria Swanberg; Johan Öckinger; Margarita Diez; Olle Lidman; Erik Wallström; Anna Lobell; Tomas Olsson; Fredrik Piehl

J Immunol (2008) 180 (5): 3289–3296.

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HOST DEFENSE

Significant Virus Replication in Langerhans Cells following Application of HIV to Abraded Skin: Relevance to Occupational Transmission of HIV ¹

Tatsuyoshi Kawamura; Yoshio Koyanagi; Yuumi Nakamura; Youichi Ogawa; Atsuya Yamashita; Taku Iwamoto; Masahiko Ito; Andrew Blauvelt; Shinji Shimada

J Immunol (2008) 180 (5): 3297–3304.

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Effects of Liver X Receptor Agonist Treatment on Pulmonary Inflammation and Host Defense ¹

Kathleen Smoak; Jennifer Madenspacher; Samithamby Jeyaseelan; Belinda Williams; Darlene Dixon; Katie R. Poch; Jerry A. Nick; G. Scott Worthen; Michael B. Fessler

J Immunol (2008) 180 (5): 3305–3312.

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Properdin Plays a Protective Role in Polymicrobial Septic Peritonitis ¹

Cordula M. Stover; Jeni C. Luckett; Bernd Echtenacher; Aline Dupont; Sue E. Figgitt; Jane Brown; Daniela N. Männel; Wilhelm J. Schwaeble

J Immunol (2008) 180 (5): 3313–3318.

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Airway Epithelial versus Immune Cell Stat1 Function for Innate Defense against Respiratory Viral Infection ¹

Laurie P. Shornick; Audrey G. Wells; Yong Zhang; Anand C. Patel; Guangming Huang; Kazutaka Takami; Moises Sosa; Nikhil A. Shukla; Eugene Agapov; Michael J. Holtzman

J Immunol (2008) 180 (5): 3319–3328.

Supplementary data

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Fcγ Receptors Regulate Immune Activation and Susceptibility during Mycobacterium tuberculosis Infection ¹

Paul J. Maglione; Jiayong Xu; Arturo Casadevall; John Chan

J Immunol (2008) 180 (5): 3329–3338.

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MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines ¹

Peter Johannes Holst; Maria Rathmann Sorensen; Camilla Maria Mandrup Jensen; Cathrine Orskov; Allan Randrup Thomsen; Jan Pravsgaard Christensen

J Immunol (2008) 180 (5): 3339–3346.

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Glycosylation-Dependent Interactions of C-Type Lectin DC-SIGN with Colorectal Tumor-Associated Lewis Glycans Impair the Function and Differentiation of Monocyte-Derived Dendritic Cells ¹

Motohiro Nonaka; Bruce Yong Ma; Ryuuya Murai; Natsuko Nakamura; Makoto Baba; Nobuko Kawasaki; Keiko Hodohara; Shinji Asano; Toshisuke Kawasaki

J Immunol (2008) 180 (5): 3347–3356.

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Platelet-Activating Factor Receptor Contributes to Host Defense against Pseudomonas aeruginosa Pneumonia but Is Not Essential for the Accompanying Inflammatory and Procoagulant Response ¹

Marieke A. D. van Zoelen; Sandrine Florquin; Joost C. M. Meijers; Regina de Beer; Alex F. de Vos; Onno J. de Boer; Tom van der Poll

J Immunol (2008) 180 (5): 3357–3365.

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Blockade of Antimicrobial Proteins S100A8 and S100A9 Inhibits Phagocyte Migration to the Alveoli in Streptococcal Pneumonia ¹

Marie-Astrid Raquil; Nadia Anceriz; Pascal Rouleau; Philippe A. Tessier

J Immunol (2008) 180 (5): 3366–3374.

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Antigen-Specific CD4⁺ T Cells Produce Sufficient IFN-γ to Mediate Robust Protective Immunity against Genital Chlamydia muridarum Infection ¹

Weidang Li; Ashlesh K. Murthy; M. Neal Guentzel; J. Seshu; Thomas G. Forsthuber; Guangming Zhong; Bernard P. Arulanandam

J Immunol (2008) 180 (5): 3375–3382.

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Fine Specificity of Neonatal Lymphocytes to an Abundant Malaria Blood-Stage Antigen: Epitope Mapping of Plasmodium falciparum MSP1₃₃ ¹

Indu Malhotra; Alex N. Wamachi; Peter L. Mungai; Elton Mzungu; Davy Koech; Eric Muchiri; Ann M. Moormann; Christopher L. King

J Immunol (2008) 180 (5): 3383–3390.

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Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses ¹

Patrick C. Reading; Silvia Bozza; Brad Gilbertson; Michelle Tate; Silvia Moretti; Emma R. Job; Erika C. Crouch; Andrew G. Brooks; Lorena E. Brown; Barbara Bottazzi; Luigina Romani; Alberto Mantovani

J Immunol (2008) 180 (5): 3391–3398.

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Human Lymphatic Endothelial Cells Express Multiple Functional TLRs ¹

Amarendra Pegu; Shulin Qin; Beth A. Fallert Junecko; Riccardo E. Nisato; Michael S. Pepper; Todd A. Reinhart

J Immunol (2008) 180 (5): 3399–3405.

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Stimulation of Enhanced CD8 T Cell Responses Following Immunization with a Hyper-Antigen Secreting Intracytosolic Bacterial Pathogen ¹

Megan J. Smithey; Suzanne Brandt; Nancy E. Freitag; Darren E. Higgins; H. G. Archie Bouwer

J Immunol (2008) 180 (5): 3406–3416.

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γδ⁺ T Cells Involvement in Viral Immune Control of Chronic Human Herpesvirus 8 Infection ¹

Serge Barcy; Stephen C. De Rosa; Jeffrey Vieira; Kurt Diem; Minako Ikoma; Corey Casper; Lawrence Corey

J Immunol (2008) 180 (5): 3417–3425.

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Human Factor H Interacts Selectively with Neisseria gonorrhoeae and Results in Species-Specific Complement Evasion ¹

Jutamas Ngampasutadol; Sanjay Ram; Sunita Gulati; Sarika Agarwal; Chongqing Li; Alberto Visintin; Brian Monks; Guillermo Madico; Peter A. Rice

J Immunol (2008) 180 (5): 3426–3435.

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Mycobacterial Lipopeptides Elicit CD4⁺ CTLs in Mycobacterium tuberculosis-Infected Humans ¹

Max Bastian; Tobias Braun; Heiko Bruns; Martin Röllinghoff; Steffen Stenger

J Immunol (2008) 180 (5): 3436–3446.

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INFLAMMATION

Inhibition of Monocyte Chemoattractant Protein-1 Ameliorates Rat Adjuvant-Induced Arthritis ¹

Shiva Shahrara; Amanda E. I. Proudfoot; Christy C. Park; Michael V. Volin; G. Kenneth Haines; James M. Woods; Christopher H. Aikens; Tracy M. Handel; Richard M. Pope

J Immunol (2008) 180 (5): 3447–3456.

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Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice

J Immunol (2008) 180 (5): 3457–3466.

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Lymphotoxin-α1β2 and LIGHT Induce Classical and Noncanonical NF-κB-Dependent Proinflammatory Gene Expression in Vascular Endothelial Cells ¹

Lisa A. Madge; Martin S. Kluger; Jordan S. Orange; Michael J. May

J Immunol (2008) 180 (5): 3467–3477.

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Lipoteichoic Acid-Induced Lung Inflammation Depends on TLR2 and the Concerted Action of TLR4 and the Platelet-Activating Factor Receptor

Sylvia Knapp; Sonja von Aulock; Masja Leendertse; Isabella Haslinger; Christian Draing; Douglas T. Golenbock; Tom van der Poll

J Immunol (2008) 180 (5): 3478–3484.

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Etk/BMX, a Btk Family Tyrosine Kinase, and Mal Contribute to the Cross-Talk between MyD88 and FAK Pathways ¹

Noha Semaan; Ghada Alsaleh; Jacques-Eric Gottenberg; Dominique Wachsmann; Jean Sibilia

J Immunol (2008) 180 (5): 3485–3491.

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Transcriptional Complex Formation of c-Fos, STAT3, and Hepatocyte NF-1α Is Essential for Cytokine-Driven C-Reactive Protein Gene Expression ¹

Teppei Nishikawa; Keisuke Hagihara; Satoshi Serada; Tomoyasu Isobe; Atsumi Matsumura; Jian Song; Toshio Tanaka; Ichiro Kawase; Tetsuji Naka; Kazuyuki Yoshizaki

J Immunol (2008) 180 (5): 3492–3501.

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Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin ¹

Lynne R. Prince; Stephen M. Bianchi; Kathryn M. Vaughan; Martin A. Bewley; Helen M. Marriott; Sarah R. Walmsley; Graham W. Taylor; David J. Buttle; Ian Sabroe; David H. Dockrell; Moira K. B. Whyte

J Immunol (2008) 180 (5): 3502–3511.

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Resolvin E1 Metabolome in Local Inactivation during Inflammation-Resolution ¹

Song Hong; Timothy F. Porter; Yan Lu; Sungwhan F. Oh; Padmini S. Pillai; Charles N. Serhan

J Immunol (2008) 180 (5): 3512–3519.

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Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and Positive and Negative Cross-Talk with Bacterial Lipopolysaccharide

Ken Dower; Debra K. Ellis; Kathryn Saraf; Scott A. Jelinsky; Lih-Ling Lin

J Immunol (2008) 180 (5): 3520–3534.

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Dipeptidyl Peptidase I-Dependent Neutrophil Recruitment Modulates the Inflammatory Response to Sendai Virus Infection ¹

Antonina M. Akk; Pamela M. Simmons; Happy W. Chan; Eugene Agapov; Michael J. Holtzman; Mitchell H. Grayson; Christine T. N. Pham

J Immunol (2008) 180 (5): 3535–3542.

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Mast Cell-Fibroblast Interactions Induce Matrix Metalloproteinase-9 Release from Fibroblasts: Role for IgE-Mediated Mast Cell Activation ¹

Melanie Abel; Harissios Vliagoftis

J Immunol (2008) 180 (5): 3543–3550.

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IL-4 Is a Critical Determinant in the Generation of Allergic Inflammation Initiated by a Constitutively Active Stat6

Sarita Sehra; Heather A. Bruns; Ayele-Nati N. Ahyi; Evelyn T. Nguyen; Nathan W. Schmidt; E. Grace Michels; Götz-Ulrich von Bülow; Mark H. Kaplan

J Immunol (2008) 180 (5): 3551–3559.

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Loss of ABCG1 Results in Chronic Pulmonary Inflammation ¹

Ángel Baldán; Aldrin V. Gomes; Peipei Ping; Peter A. Edwards

J Immunol (2008) 180 (5): 3560–3568.

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CLINICAL IMMUNOLOGY

Bacillus Calmette-Guérin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles ¹

Andreia P. Soares; Thomas J. Scriba; Sarah Joseph; Ryhor Harbacheuski; Rose Ann Murray; Sebastian J. Gelderbloem; Anthony Hawkridge; Gregory D. Hussey; Holden Maecker; Gilla Kaplan; Willem A. Hanekom

J Immunol (2008) 180 (5): 3569–3577.

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Questionable Relevance of γδ T Lymphocytes in Renal Cell Carcinoma ¹

Brant A. Inman; Xavier Frigola; Kimberley J. Harris; Susan M. Kuntz; Christine M. Lohse; Bradley C. Leibovich; Eugene D. Kwon

J Immunol (2008) 180 (5): 3578–3584.

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Vaccination of a Melanoma Patient with Mature Dendritic Cells Pulsed with MAGE-3 Peptides Triggers the Activity of Nonvaccine Anti-Tumor Cells ¹

Javier Carrasco; Aline Van Pel; Bart Neyns; Bernard Lethé; Francis Brasseur; Nicolina Renkvist; Pierre van der Bruggen; Nicolas van Baren; Robert Paulus; Kris Thielemans; Thierry Boon; Danièle Godelaine

J Immunol (2008) 180 (5): 3585–3593.

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Morphine Induces Defects in Early Response of Alveolar Macrophages to Streptococcus pneumoniae by Modulating TLR9-NF-κB Signaling ¹

Jinghua Wang; Roderick A. Barke; Richard Charboneau; Reto Schwendener; Sabita Roy

J Immunol (2008) 180 (5): 3594–3600.

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Redirecting Therapeutic T Cells against Myelin-Specific T Lymphocytes Using a Humanized Myelin Basic Protein-HLA-DR2-ζ Chimeric Receptor ¹

Ioana Moisini; Phuong Nguyen; Lars Fugger; Terrence L. Geiger

J Immunol (2008) 180 (5): 3601–3611.

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CORRECTIONS

Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8⁺ T cells

F. Masson; T. Calzascia; W. Di Berardino-Besson; N. de Tribolet; P.-Y. Dietrich; P. R. Walker

J Immunol (2008) 180 (5): 3612.

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Cutting edge: a transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway

K. C. El Kasmi; A. M. Smith; L. Williams; G. Neale; A. Panopolous; S. S. Watowich; H. Häcker; B. M. J. Foxwell; P. J. Murray

J Immunol (2008) 180 (5): 3612.

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Membrane vesicles are immunogenic facsimiles of Salmonella typhimurium that potently activate dendritic cells, prime B and T cell responses, and stimulate protective immunity in vivo

R. C. Alaniz; B. L. Deatherage; J. C. Lara; B. T. Cookson

J Immunol (2008) 180 (5): 3612.

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TLR ligands differentially modulate T cell responses to acute and chronic antigen presentation

N. J. Singh; M. Cox; R. H. Schwartz

J Immunol (2008) 180 (5): 3612.

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Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins

Y. Li; J. Yan; P. De; H.-C. Chang; A. Yamauchi; K. W. Christopherson, II; N. C. Paranavitana; X. Peng; C. Kim; V. Munugulavadla; R. Kapur; H. Chen; W. Shou; J. C. Stone; M. H. Kaplan; M. C. Dinauer; D. L. Durden; L. A. Quilliam

J Immunol (2008) 180 (5): 3612.

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ICOS controls the pool size of effector-memory and regulatory T cells

Y. Burmeister; T. Lischke; A. C. Dahler; H. W. Mages; K.-P. Lam; A. J. Coyle; R. A. Kroczek; A. Hutloff

J Immunol (2008) 180 (5): 3613.

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Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers

K. Khosrotehrani; M. Leduc; V. Bachy; S. N. Huu; M. Oster; A. Abbas; S. Uzan; S. Aractingi

J Immunol (2008) 180 (5): 3613.

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Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2

R. J. Nunes; M. A. A. Castro; C. M. Gonçalves; M. Bamberger; C. F. Pereira; G. Bismuth; A. M. Carmo

J Immunol (2008) 180 (5): 3613.

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Role of the β-subunit arginine/lysine finger in integrin heterodimer formation and function

V. Gupta; J. L. Alonso; T. Sugimori; M. Issafi; J.-P. Xiong; M. A. Arnaout

J Immunol (2008) 180 (5): 3613.

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Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis

L. Schiffer; R. Bethunaickan; M. Ramanujam; W. Huang; M. Schiffer; H. Tao; M. M. Madaio; E. P. Bottinger; A. Davidson

J Immunol (2008) 180 (5): 3613.

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Cover Image

Cover Image

On the cover: Nonaka, M., B. Y. Ma, R. Murai, N. Nakamura, M. Baba, N. Kawasaki, K. Hodohara, S. Asano, and T. Kawasaki. 2008. Glycosylation-dependent interactions of C-type lectin DC-SIGN with colorectal tumor-associated Lewis glycans impair the function and differentiation of monocyte-derived dendritic cells. Immunohistochemistry of human moderately differentiated sigmoid colon adenocarcinoma. The deparaffinized cryosection was stained with anti-DC-SIGN (green) and anti-Lea glycan (red) mAbs. The association of DC-SIGN-expressing DCs with colon adenocarcinoma epithelia expressing Lea glycans in situ was visualized by confocal microscopy. J. Immunol. 180: 3347–3356.
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