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TLR2-Dependent MyD88 Signaling Contributes to Early Host Defense in Murine Enterococcus faecium Peritonitis
Masja Leendertse; Rob J. L. Willems; Ida A. J. Giebelen; Petra S. van den Pangaart; W. Joost Wiersinga; Alex F. de Vos; Sandrine Florquin; Marc J. M. Bonten; Tom van der Poll
J Immunol (2008) 180 (7): 4865–4874.
TIM-4 Expressed on APCs Induces T Cell Expansion and Survival1
Roselynn Rodriguez-Manzanet; Jennifer Hartt Meyers; Savithri Balasubramanian; Jacqueline Slavik; Nasim Kassam; Valerie Dardalhon; Edward A. Greenfield; Ana C. Anderson; Raymond A. Sobel; David A. Hafler; Terry B. Strom; Vijay K. Kuchroo
J Immunol (2008) 180 (7): 4706–4713.
Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice1
Balasubramanian Krishnamurthy; Lina Mariana; Shane A. Gellert; Peter G. Colman; Leonard C. Harrison; Andrew M. Lew; Pere Santamaria; Helen E. Thomas; Thomas W. H. Kay
J Immunol (2008) 180 (7): 4458–4464.
CD209+ Macrophages Mediate Host Defense against Propionibacterium acnes1
Philip T. Liu; Jenny Phan; Dominic Tang; Melissa Kanchanapoomi; Brian Hall; Stephan R. Krutzik; Jenny Kim
J Immunol (2008) 180 (7): 4919–4923.
TLR2 Regulates Gap Junction Intercellular Communication in Airway Cells1
J Immunol (2008) 180 (7): 4986–4993.
Brief Antigenic Stimulation Generates Effector CD8 T Cells with Low Cytotoxic Activity and High IL-2 Production1
J Immunol (2008) 180 (7): 4507–4513.
Gastrointestinal Dendritic Cells Promote Th2 Skewing via OX40L1
J Immunol (2008) 180 (7): 4441–4450.
CD40 on APCs Is Needed for Optimal Programming, Maintenance, and Recall of CD8+ T Cell Memory Even in the Absence of CD4+ T Cell Help1
J Immunol (2008) 180 (7): 4382–4390.
Intracellular Retention of the NKG2D Ligand MHC Class I Chain-Related Gene A in Human Melanomas Confers Immune Privilege and Prevents NK Cell-Mediated Cytotoxicity1
Mercedes B. Fuertes; María V. Girart; Luciana L. Molinero; Carolina I. Domaica; Lucas E. Rossi; María M. Barrio; José Mordoh; Gabriel A. Rabinovich; Norberto W. Zwirner
J Immunol (2008) 180 (7): 4606–4614.
Apoptotic Cells Protect Mice against Lipopolysaccharide-Induced Shock1
J Immunol (2008) 180 (7): 4978–4985.
TRAIL Deficiency Does Not Rescue Impaired CD8+ T Cell Memory Generated in the Absence of CD4+ T Cell Help1
J Immunol (2008) 180 (7): 4570–4576.
Hypoxia and Hypoxia-Inducible Factor-1α Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function1
Jonathan Jantsch; Dipshikha Chakravortty; Nadine Turza; Alexander T. Prechtel; Björn Buchholz; Roman G. Gerlach; Melanie Volke; Joachim Gläsner; Christina Warnecke; Michael S. Wiesener; Kai-Uwe Eckardt; Alexander Steinkasserer; Michael Hensel; Carsten Willam
J Immunol (2008) 180 (7): 4697–4705.
Villous B Cells of the Small Intestine Are Specialized for Invariant NK T Cell Dependence1
Peter Velázquez; Bo Wei; Michael McPherson; Lesley Marie A. Mendoza; Sandra L. Nguyen; Olga Turovskaya; Mitchell Kronenberg; Tiffany T. Huang; Matthew Schrage; Lynn N. Lobato; Daisuke Fujiwara; Sarah Brewer; Moshe Arditi; Genhong Cheng; R. Balfour Sartor; Rodney D. Newberry; Jonathan Braun
J Immunol (2008) 180 (7): 4629–4638.
IL-2/Anti-IL-2 Antibody Complex Enhances Vaccine-Mediated Antigen-Specific CD8+ T Cell Responses and Increases the Ratio of Effector/Memory CD8+ T Cells to Regulatory T Cells1
Sven Mostböck; M. E. Christine Lutsiak; Diane E. Milenic; Kwamena Baidoo; Jeffrey Schlom; Helen Sabzevari
J Immunol (2008) 180 (7): 5118–5129.
Inhibition of TLR Activation and Up-Regulation of IL-1R-Associated Kinase-M Expression by Exogenous Gangliosides1
J Immunol (2008) 180 (7): 4425–4432.
Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity1
Keith Hamel; Paul Doodes; Yanxia Cao; Yumei Wang; Jeffrey Martinson; Robert Dunn; Marilyn R. Kehry; Balint Farkas; Alison Finnegan
J Immunol (2008) 180 (7): 4994–5003.
Relative Levels of M-CSF and GM-CSF Influence the Specific Generation of Macrophage Populations during Infection with Mycobacterium tuberculosis1
David M. Higgins; Joaquin Sanchez-Campillo; Adrian G. Rosas-Taraco; Jonathan R. Higgins; Eric J. Lee; Ian M. Orme; Mercedes Gonzalez-Juarrero
J Immunol (2008) 180 (7): 4892–4900.
Induction of Antitumor Immune Response by Homeostatic Proliferation and CD28 Signaling
J Immunol (2008) 180 (7): 4596–4605.
Renal Cell Carcinoma Tumors Induce T Cell Apoptosis through Receptor-Dependent and Receptor-Independent Pathways1
Tanya Das; Gaurisankar Sa; Ewa Paszkiewicz-Kozik; Cynthia Hilston; Luis Molto; Patricia Rayman; Daisuke Kudo; Kaushik Biswas; Ronald M. Bukowski; James H. Finke; Charles S. Tannenbaum
J Immunol (2008) 180 (7): 4687–4696.
Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes1
Carina L. Pérez; Mette V. Larsen; Rasmus Gustafsson; Melissa M. Norström; Ann Atlas; Douglas F. Nixon; Morten Nielsen; Ole Lund; Annika C. Karlsson
J Immunol (2008) 180 (7): 5092–5100.
Nonhuman Primate IgA: Genetic Heterogeneity and Interactions with CD8912
J Immunol (2008) 180 (7): 4816–4824.
IL-15 Transpresentation Augments CD8+ T Cell Activation and Is Required for Optimal Recall Responses by Central Memory CD8+ T Cells1
J Immunol (2008) 180 (7): 4391–4401.
Complement Receptors 1 and 2 Influence the Immune Environment in a B Cell Receptor-Independent Manner12
J Immunol (2008) 180 (7): 5057–5066.
Dendritic Cell Programming by Cytomegalovirus Stunts Naive T Cell Responses via the PD-L1/PD-1 Pathway1
J Immunol (2008) 180 (7): 4836–4847.
Immunodominance in the TCR Repertoire of αTCR Peptide-Specific CD4+ Treg Population That Controls Experimental Autoimmune Encephalomyelitis1
J Immunol (2008) 180 (7): 4577–4585.
Macrophage Deletion of p38α Partially Impairs Lipopolysaccharide-Induced Cellular Activation1
J Immunol (2008) 180 (7): 5075–5082.
Differential Initiation of Innate Immune Responses Induced by Human Cytomegalovirus Entry into Fibroblast Cells1
J Immunol (2008) 180 (7): 4965–4977.
Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF-κB, Suppresses IκBα Ubiquitination and Modulates Innate Immune Responses1
Gaëlle Le Negrate; Benjamin Faustin; Kate Welsh; Markus Loeffler; Maryla Krajewska; Patty Hasegawa; Sohini Mukherjee; Kim Orth; Stan Krajewski; Adam Godzik; Donald G. Guiney; John C. Reed
J Immunol (2008) 180 (7): 5045–5056.
Molecular Characterization of Helicobacter pylori VacA Induction of IL-8 in U937 Cells Reveals a Prominent Role for p38MAPK in Activating Transcription Factor-2, cAMP Response Element Binding Protein, and NF-κB Activation1
Junzo Hisatsune; Masaaki Nakayama; Hajime Isomoto; Hisao Kurazono; Naofumi Mukaida; Asish K. Mukhopadhyay; Takeshi Azuma; Yoshio Yamaoka; Jan Sap; Eiki Yamasaki; Kinnosuke Yahiro; Joel Moss; Toshiya Hirayama
J Immunol (2008) 180 (7): 5017–5027.
Isoform-Specific Inhibition of RORα-Mediated Transcriptional Activation by Human FOXP31
J Immunol (2008) 180 (7): 4785–4792.
Invariant NKT Cells Promote CD8+ Cytotoxic T Cell Responses by Inducing CD70 Expression on Dendritic Cells1
Vadim Y. Taraban; Sonya Martin; Kathrine E. Attfield; Martin J. Glennie; Tim Elliott; Dirk Elewaut; Serge Van Calenbergh; Bruno Linclau; Aymen Al-Shamkhani
J Immunol (2008) 180 (7): 4615–4620.
Protection against Influenza A Virus by Memory CD8 T Cells Requires Reactivation by Bone Marrow-Derived Dendritic Cells1
J Immunol (2008) 180 (7): 4956–4964.
Combined CXCR3/CCR5 Blockade Attenuates Acute and Chronic Rejection1
Gabriel T. Schnickel; Sam Bastani; George R. Hsieh; Ali Shefizadeh; Rubina Bhatia; Michael C. Fishbein; John Belperio; Abbas Ardehali
J Immunol (2008) 180 (7): 4714–4721.
Selective Roles of MAPKs during the Macrophage Response to IFN-γ1
Annabel F. Valledor; Ester Sánchez-Tilló; Luis Arpa; Jin Mo Park; Carme Caelles; Jorge Lloberas; Antonio Celada
J Immunol (2008) 180 (7): 4523–4529.
Leishmania major-Specific B Cells Are Necessary for Th2 Cell Development and Susceptibility to L. major LV39 in BALB/c Mice1
Catherine Ronet; Heike Voigt; Hayo Himmelrich; Marie-Agnès Doucey; Yazmin Hauyon-La Torre; Mélanie Revaz-Breton; Fabienne Tacchini-Cottier; Claude Bron; Jacques Louis; Pascal Launois
J Immunol (2008) 180 (7): 4825–4835.
Impact of Post-Thymic Cellular Longevity on the Development of Age-Associated CD4+ T Cell Defects1
Stephen C. Jones; Karen Clise-Dwyer; Gail Huston; John Dibble; Sheri Eaton; Laura Haynes; Susan L. Swain
J Immunol (2008) 180 (7): 4465–4475.
Innate-Like Effector Differentiation of Human Invariant NKT Cells Driven by IL-71
Claudia de Lalla; Nicola Festuccia; Inka Albrecht; Hyun-Dong Chang; Grazia Andolfi; Ulrike Benninghoff; Ferdinando Bombelli; Giovanna Borsellino; Alessandro Aiuti; Andreas Radbruch; Paolo Dellabona; Giulia Casorati
J Immunol (2008) 180 (7): 4415–4424.
NK Cells Contribute to Intracellular Bacterial Infection-Mediated Inhibition of Allergic Responses1
J Immunol (2008) 180 (7): 4621–4628.
Regulatory T Cells Control Dendritic Cell/NK Cell Cross-Talk in Lymph Nodes at the Steady State by Inhibiting CD4+ Self-Reactive T Cells
J Immunol (2008) 180 (7): 4679–4686.
The Synthetic Peroxisome Proliferator-Activated Receptor-γ Agonist Ciglitazone Attenuates Neuroinflammation and Accelerates Encapsulation in Bacterial Brain Abscesses1
Tammy Kielian; Mohsin Md. Syed; Shuliang Liu; Nirmal K. Phulwani; Napoleon Phillips; Gail Wagoner; Paul D. Drew; Nilufer Esen
J Immunol (2008) 180 (7): 5004–5016.
Homeostasis and Effector Function of Lymphopenia-Induced “Memory-Like” T Cells in Constitutively T Cell-Depleted Mice1
J Immunol (2008) 180 (7): 4742–4753.
Blockade of PD-1/B7-H1 Interaction Restores Effector CD8+ T Cell Responses in a Hepatitis C Virus Core Murine Model1
J Immunol (2008) 180 (7): 4875–4884.
Doc2α and Munc13-4 Regulate Ca2+-Dependent Secretory Lysosome Exocytosis in Mast Cells1
Hironori Higashio; Noriyuki Nishimura; Hiroyoshi Ishizaki; Jun Miyoshi; Satoshi Orita; Ayuko Sakane; Takuya Sasaki
J Immunol (2008) 180 (7): 4774–4784.
CD4+ T Lymphocytes Are Not Necessary for the Acute Rejection of Vascularized Mouse Lung Transplants1
Andrew E. Gelman; Mikio Okazaki; Jiaming Lai; Christopher G. Kornfeld; Friederike H. Kreisel; Steven B. Richardson; Seiichiro Sugimoto; Jeremy R. Tietjens; G. Alexander Patterson; Alexander S. Krupnick; Daniel Kreisel
J Immunol (2008) 180 (7): 4754–4762.
The Presence of Activated CD4+ T Cells Is Essential for the Formation of Colony-Forming Unit-Endothelial Cells by CD14+ Cells
Rachel T. van Beem; Willy A. Noort; Carlijn Voermans; Marion Kleijer; Anja ten Brinke; S. Marieke van Ham; C. Ellen van der Schoot; Jaap Jan Zwaginga
J Immunol (2008) 180 (7): 5141–5148.
Aberrant Genetic Control of Invariant TCR-Bearing NKT Cell Function in New Zealand Mouse Strains: Possible Involvement in Systemic Lupus Erythematosus Pathogenesis1
Kazuyuki Tsukamoto; Mareki Ohtsuji; Wakana Shiroiwa; Qingshun Lin; Kazuhiro Nakamura; Hiromichi Tsurui; Yi Jiang; Katsuko Sudo; Hiroyuki Nishimura; Toshikazu Shirai; Sachiko Hirose
J Immunol (2008) 180 (7): 4530–4539.
Intercellular Adhesion Molecule-3 Binding of Integrin αLβ2 Requires Both Extension and Opening of the Integrin Headpiece1
J Immunol (2008) 180 (7): 4793–4804.
Protein Kinase Cα and ζ Differentially Regulate Death-Inducing Signaling Complex Formation in Cigarette Smoke Extract-Induced Apoptosis1
Jeong-Woong Park; Hong Pyo Kim; Seon-Jin Lee; Xue Wang; Yong Wang; Emeka Ifedigbo; Simon C. Watkins; Motoi Ohba; Stefan W. Ryter; Yatin M. Vyas; Augustine M. K. Choi
J Immunol (2008) 180 (7): 4668–4678.
CXCL13, CCL21, and CXCL12 Expression in Salivary Glands of Patients with Sjögren’s Syndrome and MALT Lymphoma: Association with Reactive and Malignant Areas of Lymphoid Organization1
Francesca Barone; Michele Bombardieri; Manuela Maria Rosado; Peter Roger Morgan; Stephen J. Challacombe; Salvatore De Vita; Rita Carsetti; Jo Spencer; Guido Valesini; Costantino Pitzalis
J Immunol (2008) 180 (7): 5130–5140.
Multivectorial Abnormal Cell Migration in the NOD Mouse Thymus1
J Immunol (2008) 180 (7): 4639–4647.
Macrophages Produce TGF-β-Induced (β-ig-h3) following Ingestion of Apoptotic Cells and Regulate MMP14 Levels and Collagen Turnover in Fibroblasts1
Natalia Nacu; Irina G. Luzina; Kendrick Highsmith; Virginia Lockatell; Kerill Pochetuhen; Zachary A. Cooper; Michael P. Gillmeister; Nevins W. Todd; Sergei P. Atamas
J Immunol (2008) 180 (7): 5036–5044.
Inducing Antitumor T Cell Immunity: Comparative Functional Analysis of Interstitial Versus Langerhans Dendritic Cells in a Human Cell Line Model
Saskia J. A. M. Santegoets; Hetty J. Bontkes; Anita G. M. Stam; Farien Bhoelan; Janneke J. Ruizendaal; Alfons J. M. van den Eertwegh; Erik Hooijberg; Rik J. Scheper; Tanja D. de Gruijl
J Immunol (2008) 180 (7): 4540–4549.
Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor1
Scott Wilkie; Gianfranco Picco; Julie Foster; David M. Davies; Sylvain Julien; Lucienne Cooper; Sefina Arif; Stephen J. Mather; Joyce Taylor-Papadimitriou; Joy M. Burchell; John Maher
J Immunol (2008) 180 (7): 4901–4909.
Cutting Edge: Langerin+ Dendritic Cells in the Mesenteric Lymph Node Set the Stage for Skin and Gut Immune System Cross-Talk1
Sun-Young Chang; Hye-Ran Cha; Osamu Igarashi; Paul D. Rennert; Adrien Kissenpfennig; Bernard Malissen; Masanobu Nanno; Hiroshi Kiyono; Mi-Na Kweon
J Immunol (2008) 180 (7): 4361–4365.
Pillars Article: Theta Isoantigen as a Marker of Thymus-Derived Lymphocytes in Mice. Nature 1969. 224: 378–379.
J Immunol (2008) 180 (7): 4353–4354.
IL-13 Attenuates Gastrointestinal Candidiasis in Normal and Immunodeficient RAG-2−/− Mice via Peroxisome Proliferator-Activated Receptor-γ Activation1
Agnès Coste; Céline Lagane; Cédric Filipe; Hélène Authier; Amandine Galès; José Bernad; Victorine Douin-Echinard; Jean-Claude Lepert; Patricia Balard; Marie-Denise Linas; Jean-François Arnal; Johan Auwerx; Bernard Pipy
J Immunol (2008) 180 (7): 4939–4947.
Phosphatidylinositol 3-Kinase and Xanthine Oxidase Regulate Nitric Oxide and Reactive Oxygen Species Productions by Apoptotic Lymphocyte Microparticles in Endothelial Cells1
H. Ahmed Mostefai; Abdelali Agouni; Nunzia Carusio; M. Letizia Mastronardi; Christophe Heymes; Daniel Henrion; Ramaroson Andriantsitohaina; M. Carmen Martinez
J Immunol (2008) 180 (7): 5028–5035.
Age-Related Dysregulation of CD8+ T Cell Memory Specific for a Persistent Virus Is Independent of Viral Replication1
J Immunol (2008) 180 (7): 4848–4857.
Assessment of Bet v 1-Specific CD4+ T Cell Responses in Allergic and Nonallergic Individuals Using MHC Class II Peptide Tetramers1
Laurence Van Overtvelt; Erik Wambre; Bernard Maillère; Eric von Hofe; Anne Louise; Anne Marie Balazuc; Barbara Bohle; Didier Ebo; Christophe Leboulaire; Gilles Garcia; Philippe Moingeon
J Immunol (2008) 180 (7): 4514–4522.
STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation1
Sean A. Diehl; Heike Schmidlin; Maho Nagasawa; Simon D. van Haren; Mark J. Kwakkenbos; Etsuko Yasuda; Tim Beaumont; Ferenc A. Scheeren; Hergen Spits
J Immunol (2008) 180 (7): 4805–4815.
IL-4Rα Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis1
J Immunol (2008) 180 (7): 4948–4955.
Cutting Edge: Autoimmune Disease in Day 3 Thymectomized Mice Is Actively Controlled by Endogenous Disease-Specific Regulatory T Cells1
J Immunol (2008) 180 (7): 4366–4370.
Dendritic Cell-Dependent Inhibition of B Cell Proliferation Requires CD221
J Immunol (2008) 180 (7): 4561–4569.
A Novel Type I IFN-Producing Cell Subset in Murine Lupus1
Pui Y. Lee; Jason S. Weinstein; Dina C. Nacionales; Philip O. Scumpia; Yi Li; Edward Butfiloski; Nico van Rooijen; Lyle Moldawer; Minoru Satoh; Westley H. Reeves
J Immunol (2008) 180 (7): 5101–5108.
Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions1
Liangchun Wang; Laura S. Bursch; Adrien Kissenpfennig; Bernard Malissen; Stephen C. Jameson; Kristin A. Hogquist
J Immunol (2008) 180 (7): 4722–4727.
Human CD4+ T Cells Recognize an Epitope within α-Fetoprotein Sequence and Develop into TGF-β-Producing CD4+ T Cells1
J Immunol (2008) 180 (7): 5109–5117.
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Cover Image
Cover Image
On the cover: Integrin αLβ2 mediates leukocyte adhesion and migration on cells expressing the intercellular adhesion molecules (ICAMs). Transition of αLβ2 from a bent conformation (illustrated) to an extended conformation is a hallmark of αLβ2 activation and the opening of the αLβ2 headpiece could fine regulate the binding of αLβ2 to different ICAMs.Tang, X.-Y., Y.-F. Li, and S.-M. Tan. 2008. Intercellular adhesion molecule-3 binding of integrin αLβ2 requires both extension and opening of the integrin headpiece. J. Immunol. 180: 4793–4804.
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