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TLR/MyD88 and Liver X Receptor α Signaling Pathways Reciprocally Control Chlamydia pneumoniae-Induced Acceleration of Atherosclerosis1
Yoshikazu Naiki; Rosalinda Sorrentino; Michelle H. Wong; Kathrin S. Michelsen; Kenichi Shimada; Shuang Chen; Atilla Yilmaz; Anatoly Slepenkin; Nicolas W. J. Schröder; Timothy R. Crother; Yonca Bulut; Terence M. Doherty; Michelle Bradley; Zory Shaposhnik; Ellena M. Peterson; Peter Tontonoz; Prediman K. Shah; Moshe Arditi
J Immunol (2008) 181 (10): 7176–7185.
Multiple Glycines in TCR α-Chains Determine Clonally Diverse Nature of Human T Cell Memory to Influenza A Virus1
J Immunol (2008) 181 (10): 7407–7419.
Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis
Afsaneh Mozaffarian; Avery W. Brewer; Esther S. Trueblood; Irina G. Luzina; Nevins W. Todd; Sergei P. Atamas; Heather A. Arnett
J Immunol (2008) 181 (10): 7243–7253.
Caspase 6 Regulates B Cell Activation and Differentiation into Plasma Cells1
J Immunol (2008) 181 (10): 6810–6819.
Transgenic Mice Expressing Dominant-Negative Bright Exhibit Defects in B1 B Cells1
Jamee C. Nixon; Scott Ferrell; Cathrine Miner; Athenia L. Oldham; Ute Hochgeschwender; Carol F. Webb
J Immunol (2008) 181 (10): 6913–6922.
Active Caspase-1-Mediated Secretion of Retinoic Acid Inducible Gene-I1
J Immunol (2008) 181 (10): 7324–7331.
PI4P5-Kinase Iα Is Required for Efficient HIV-1 Entry and Infection of T Cells1
Marta Barrero-Villar; Jonathan Barroso-González; J. R. Cabrero; Mónica Gordón-Alonso; Susana Álvarez-Losada; M. A. Muñoz-Fernández; Francisco Sánchez-Madrid; Agustín Valenzuela-Fernández
J Immunol (2008) 181 (10): 6882–6888.
Mechanisms of Immunity in Hydatid Disease: Implications for Vaccine Development1
J Immunol (2008) 181 (10): 6679–6685.
Measles Virus Infection in Adults Induces Production of IL-10 and Is Associated with Increased CD4+CD25+ Regulatory T Cells1
Xue-lian Yu; Yu-ming Cheng; Bi-sheng Shi; Fang-xing Qian; Feng-bin Wang; Xi-nian Liu; Hai-ying Yang; Qing-nian Xu; Tang-kai Qi; Li-jun Zha; Zheng-hong Yuan; Reena Ghildyal
J Immunol (2008) 181 (10): 7356–7366.
Prostaglandin E2 Inhibits Eosinophil Trafficking through E-Prostanoid 2 Receptors1
Eva M. Sturm; Petra Schratl; Rufina Schuligoi; Viktoria Konya; Gunter J. Sturm; Irmgard Th. Lippe; Bernhard A. Peskar; Akos Heinemann
J Immunol (2008) 181 (10): 7273–7283.
The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells1
J Immunol (2008) 181 (10): 7350–7355.
The Host Environment Regulates the Function of CD8+ Graft-versus-Host-Reactive Effector Cells1
Ronjon Chakraverty; Barry Flutter; Farnaz Fallah-Arani; Hyeon-Seok Eom; Terry Means; Giovanna Andreola; Sebastian Schwarte; Jennifer Buchli; Pete Cotter; Guiling Zhao; Megan Sykes
J Immunol (2008) 181 (10): 6820–6828.
A Novel C1q Family Member of Amphioxus Was Revealed to Have a Partial Function of Vertebrate C1q Molecule1
Yanhong Yu; Huiqing Huang; Yan Wang; Yingcai Yu; Shaochun Yuan; Shengfeng Huang; Minming Pan; Kaixia Feng; Anlong Xu
J Immunol (2008) 181 (10): 7024–7032.
Aging Impairs IFN Regulatory Factor 7 Up-Regulation in Plasmacytoid Dendritic Cells during TLR9 Activation1
J Immunol (2008) 181 (10): 6747–6756.
Dendritic Cell Differentiation Induced by a Self-Peptide Derived from Apolipoprotein E1
Tracey A. Stephens; Enayat Nikoopour; Beverly J. Rider; Matilde Leon-Ponte; Thu A. Chau; Sebastian Mikolajczak; Pratibha Chaturvedi; Edwin Lee-Chan; Richard A. Flavell; S. M. Mansour Haeryfar; Joaquin Madrenas; Bhagirath Singh
J Immunol (2008) 181 (10): 6859–6871.
Experimental Antibody Therapy of Liver Metastases Reveals Functional Redundancy between FcγRI and FcγRIV1
Marielle A. Otten; Gerben J. van der Bij; Sjef J. Verbeek; Falk Nimmerjahn; Jeffrey V. Ravetch; Robert H. J. Beelen; Jan G. J. van de Winkel; Marjolein van Egmond
J Immunol (2008) 181 (10): 6829–6836.
MHC Variant Peptide-Mediated Anergy of Encephalitogenic T Cells Requires SHP-11
J Immunol (2008) 181 (10): 6843–6849.
IFN-γ-Dependent Regulatory Circuits in Immune Inflammation Highlighted in Diabetes1
J Immunol (2008) 181 (10): 6964–6974.
The Effect of the JNK Inhibitor, JIP Peptide, on Human T Lymphocyte Proliferation and Cytokine Production1
J Immunol (2008) 181 (10): 7300–7306.
Antiviral-Activated Dendritic Cells: A Paracrine-Induced Response State1
J Immunol (2008) 181 (10): 6872–6881.
Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand1
Karen L. Mossman; M. Firoz Mian; Nicole M. Lauzon; Carlton L. Gyles; Brian Lichty; Randy Mackenzie; Navkiran Gill; Ali A. Ashkar
J Immunol (2008) 181 (10): 6702–6706.
Cutting Edge: Helminth Infection Induces IgE in the Absence of μ- or δ-Chain Expression1
Georgia Perona-Wright; Katja Mohrs; Justin Taylor; Colby Zaph; David Artis; Edward J. Pearce; Markus Mohrs
J Immunol (2008) 181 (10): 6697–6701.
Thymocyte-Dendritic Cell Interactions near Sources of CCR7 Ligands in the Thymic Cortex1
Ena Ladi; Tanja A. Schwickert; Tatyana Chtanova; Ying Chen; Paul Herzmark; Xinye Yin; Holly Aaron; Shiao Wei Chan; Martin Lipp; Badrinath Roysam; Ellen A. Robey
J Immunol (2008) 181 (10): 7014–7023.
TNF-α Is a Positive Regulatory Factor for Human Vγ2Vδ2 T Cells1
J Immunol (2008) 181 (10): 7131–7137.
TGF-β1 Attenuates Mediator Release and De Novo Kit Expression by Human Skin Mast Cells through a Smad-Dependent Pathway1
J Immunol (2008) 181 (10): 7263–7272.
Induction of Scavenger Receptor Class B Type I Is Critical for Simvastatin Enhancement of High-Density Lipoprotein-Induced Anti-Inflammatory Actions in Endothelial Cells1
Takao Kimura; Chihiro Mogi; Hideaki Tomura; Atsushi Kuwabara; Doon-Soon Im; Koichi Sato; Hitoshi Kurose; Masami Murakami; Fumikazu Okajima
J Immunol (2008) 181 (10): 7332–7340.
Ion Channels Modulating Mouse Dendritic Cell Functions1
Nicole Matzner; Irina M. Zemtsova; Nguyen Thi Xuan; Michael Duszenko; Ekaterina Shumilina; Florian Lang
J Immunol (2008) 181 (10): 6803–6809.
Enhanced Early Expansion and Maturation of Semi-Invariant NK T Cells Inhibited Autoimmune Pathogenesis in Congenic Nonobese Diabetic Mice1
J Immunol (2008) 181 (10): 6789–6796.
Human CD4+CD25+Foxp3+ Regulatory T Cells Do Not Constitutively Express IL-35
Emilie Bardel; Frédérique Larousserie; Pascaline Charlot-Rabiega; Aurore Coulomb-L'Herminé; Odile Devergne
J Immunol (2008) 181 (10): 6898–6905.
Breaking of CD8+ T Cell Tolerance through In Vivo Ligation of CD40 Results in Inhibition of Chronic Graft-versus-Host Disease and Complete Donor Cell Engraftment1
Juyang Kim; Keunhee Park; Hyun J. Kim; Jiyoung Kim; Hyun-A Kim; Daehee Jung; Hye J. Kim; Hye-Jeong Choi; Suck-Young Choi; Kwang W. Seo; Hong R. Cho; Byungsuk Kwon
J Immunol (2008) 181 (10): 7380–7389.
CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T Cells1
J Immunol (2008) 181 (10): 7033–7043.
Fibrillar Amyloid-β Peptides Activate Microglia via TLR2: Implications for Alzheimer’s Disease1
J Immunol (2008) 181 (10): 7254–7262.
NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity1
Maziar Divangahi; Serge Mostowy; François Coulombe; Robert Kozak; Loïc Guillot; Frédéric Veyrier; Koichi S. Kobayashi; Richard A. Flavell; Philippe Gros; Marcel A. Behr
J Immunol (2008) 181 (10): 7157–7165.
CD4+ and CD8+ T Cells Exhibit Differential Requirements for CCR7-Mediated Antigen Transport during Influenza Infection1
J Immunol (2008) 181 (10): 6984–6994.
Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes1
Steven Russell Fauce; Beth D. Jamieson; Allison C. Chin; Ronald T. Mitsuyasu; Stan T. Parish; Hwee L. Ng; Christina M. Ramirez Kitchen; Otto O. Yang; Calvin B. Harley; Rita B. Effros
J Immunol (2008) 181 (10): 7400–7406.
Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease1
Xiaoming Hu; Dan Zhang; Hao Pang; W. Michael Caudle; Yachen Li; Huiming Gao; Yuxin Liu; Li Qian; Belinda Wilson; Donato A. Di Monte; Syed F. Ali; Jing Zhang; Michelle L. Block; Jau-Shyong Hong
J Immunol (2008) 181 (10): 7194–7204.
Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 Cells1
J Immunol (2008) 181 (10): 7205–7213.
Negative Regulation of TCR Signaling by Linker for Activation of X Cells via Phosphotyrosine-Dependent and -Independent Mechanisms1
J Immunol (2008) 181 (10): 7055–7061.
Pleural Mesothelial Cells Express Both BLT2 and PPARα and Mount an Integrated Response to Pleural Leukotriene B41
Elisabetta Pace; Maria Ferraro; Christopher H. Mody; Mario R. Melis; Valeria Scafidi; Anna Bonanno; Mirella Profita; Antonino Giarratano; Mark Gjomarkaj
J Immunol (2008) 181 (10): 7292–7299.
Sodium-dependent glucose transporter-1 as a novel immunological player in the intestinal mucosa.
M. Palazzo; S. Gariboldi; L. Zanobbio; S. Selleri; G. F. Dusio; V. Mauro; A. Rossini; A. Balsari; Cr. Rumio
J Immunol (2008) 181 (10): 7428.
Cutting Edge: Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency Virus Induces Significant Increases in Viral Replication and CD4+ T Cell Depletion1
Ivona Pandrea; Thaidra Gaufin; Jason M. Brenchley; Rajeev Gautam; Christopher Monjure; Aarti Gautam; Clint Coleman; Andrew A. Lackner; Ruy M. Ribeiro; Daniel C. Douek; Cristian Apetrei
J Immunol (2008) 181 (10): 6687–6691.
Induction of TRAIL- and TNF-α-Dependent Apoptosis in Human Monocyte-Derived Dendritic Cells by Microfilariae of Brugia malayi1
Roshanak Tolouei Semnani; Priyanka Goel Venugopal; Lily Mahapatra; Jason A. Skinner; Francoise Meylan; Daniel Chien; David W. Dorward; Damien Chaussabel; Richard M. Siegel; Thomas B. Nutman
J Immunol (2008) 181 (10): 7081–7089.
Dynamin 2 Regulates Granule Exocytosis during NK Cell-Mediated Cytotoxicity1
Laura N. Arneson; Colin M. Segovis; Timothy S. Gomez; Renee A. Schoon; Christopher J. Dick; Zhenkun Lou; Daniel D. Billadeau; Paul J. Leibson
J Immunol (2008) 181 (10): 6995–7001.
Imatinib Mesylate Inhibits CD4+CD25+ Regulatory T Cell Activity and Enhances Active Immunotherapy against BCR-ABL− Tumors1
Nicolas Larmonier; Nona Janikashvili; Collin James LaCasse; Claire Billerey Larmonier; Jessica Cantrell; Elaine Situ; Tamara Lundeen; Bernard Bonnotte; Emmanuel Katsanis
J Immunol (2008) 181 (10): 6955–6963.
Neuropeptide Y Is Expressed by Rat Mononuclear Blood Leukocytes and Strongly Down-Regulated during Inflammation1
Julia Holler; Anna Zakrzewicz; Andreas Kaufmann; Jochen Wilhelm; Gabriele Fuchs-Moll; Hartmut Dietrich; Winfried Padberg; Jitka Kuncová; Wolfgang Kummer; Veronika Grau
J Immunol (2008) 181 (10): 6906–6912.
IFN-β Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3-β1
Huizhi Wang; Carlos A. Garcia; Kunal Rehani; Caglar Cekic; Pascale Alard; Denis F. Kinane; Thomas Mitchell; Michael Martin
J Immunol (2008) 181 (10): 6797–6802.
A New Mechanism for Inhalational Priming: IL-4 Bypasses Innate Immune Signals1
Anna M. Dittrich; Hui-Chen Chen; Lan Xu; Patricia Ranney; Sean Connolly; Timur O. Yarovinsky; H. Kim Bottomly
J Immunol (2008) 181 (10): 7307–7315.
Hyaluronan Induces Cell Death in Activated T Cells through CD441
J Immunol (2008) 181 (10): 7044–7054.
Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but Not CCL7 and CCL8, Chemokine Expression1
J Immunol (2008) 181 (10): 7341–7349.
Species-Specific Interaction of Streptococcus pneumoniae with Human Complement Factor H1
J Immunol (2008) 181 (10): 7138–7146.
IL-10 and TGF-β Redundantly Protect against Severe Liver Injury and Mortality during Acute Schistosomiasis1
J Immunol (2008) 181 (10): 7214–7220.
Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric Ulcerative Colitis1
Richard Ahrens; Amanda Waddell; Luqman Seidu; Carine Blanchard; Rebecca Carey; Elizabeth Forbes; Maria Lampinen; Tara Wilson; Elizabeth Cohen; Keith Stringer; Edgar Ballard; Ariel Munitz; Huan Xu; Nancy Lee; James J. Lee; Marc E. Rothenberg; Lee Denson; Simon P. Hogan
J Immunol (2008) 181 (10): 7390–7399.
TLR Ligands in the Local Treatment of Established Intracerebral Murine Gliomas1
Oliver M. Grauer; Johan W. Molling; Erik Bennink; Liza W. J. Toonen; Roger P. M. Sutmuller; Stefan Nierkens; Gosse J. Adema
J Immunol (2008) 181 (10): 6720–6729.
A Novel Role for Neutrophils As Critical Activators of NK Cells1
J Immunol (2008) 181 (10): 7121–7130.
Regulatory Roles for NKT Cell Ligands in Environmentally Induced Autoimmunity1
Jaya Vas; Jochen Mattner; Stewart Richardson; Rachel Ndonye; John P. Gaughan; Amy Howell; Marc Monestier
J Immunol (2008) 181 (10): 6779–6788.
Differential Regulatory Function of Resting and Preactivated Allergen-Specific CD4+CD25+ Regulatory T Cells in Th2-Type Airway Inflammation1
Kanako Saito; Mie Torii; Ning Ma; Tomoko Tsuchiya; Linan Wang; Tomohide Hori; Daisuke Nagakubo; Nao Nitta; Shiro Kanegasaki; Kunio Hieshima; Osamu Yoshie; Esteban C. Gabazza; Naoyuki Katayama; Hiroshi Shiku; Kagemasa Kuribayashi; Takuma Kato
J Immunol (2008) 181 (10): 6889–6897.
Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses1
Penelope M. Drake; Jay K. Nathan; Christina M. Stock; Pamela V. Chang; Marcus O. Muench; Daisuke Nakata; J. Rachel Reader; Phung Gip; Kevin P. K. Golden; Birgit Weinhold; Rita Gerardy-Schahn; Frederic A. Troy, II; Carolyn R. Bertozzi
J Immunol (2008) 181 (10): 6850–6858.
Role of Human CD36 in Bacterial Recognition, Phagocytosis, and Pathogen-Induced JNK-Mediated Signaling1
Irina N. Baranova; Roger Kurlander; Alexander V. Bocharov; Tatyana G. Vishnyakova; Zhigang Chen; Alan T. Remaley; Gyorgy Csako; Amy P. Patterson; Thomas L. Eggerman
J Immunol (2008) 181 (10): 7147–7156.
NF-κB-Driven STAT2 and CCL2 Expression in Astrocytes in Response to Brain Injury1
J Immunol (2008) 181 (10): 7284–7291.
Cutting Edge: Eosinophils Do Not Contribute to Respiratory Syncytial Virus Vaccine-Enhanced Disease1
J Immunol (2008) 181 (10): 6692–6696.
Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88-Dependent and -Independent Signaling and Is Reciprocally Modulated by Liver X Receptor Activation1
Shuang Chen; Rosalinda Sorrentino; Kenichi Shimada; Yonca Bulut; Terence M. Doherty; Timothy R. Crother; Moshe Arditi
J Immunol (2008) 181 (10): 7186–7193.
Respiratory Epithelial Cells Convert Inactive Vitamin D to Its Active Form: Potential Effects on Host Defense1
J Immunol (2008) 181 (10): 7090–7099.
Expression of a soluble TGF-β receptor by tumor cells enhances dendritic cell/tumor fusion vaccine efficacy.
J Immunol (2008) 181 (10): 7428.
Dendritic Cells Genetically Engineered to Express IL-10 Induce Long-Lasting Antigen-Specific Tolerance in Experimental Asthma1
Emmanuelle Henry; Christophe J. Desmet; Virginie Garzé; Laurence Fiévez; Denis Bedoret; Carlo Heirman; Pedro Faisca; Fabrice J. Jaspar; Philippe Gosset; Alain P. A. Jacquet; Daniel Desmecht; Kris Thielemans; Pierre Lekeux; Muriel Moser; Fabrice Bureau
J Immunol (2008) 181 (10): 7230–7242.
Histoplasma capsulatum Cyclophilin A Mediates Attachment to Dendritic Cell VLA-51
J Immunol (2008) 181 (10): 7106–7114.
Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis1
Emma Guttman-Yassky; Michelle A. Lowes; Judilyn Fuentes-Duculan; Lisa C. Zaba; Irma Cardinale; Kristine E. Nograles; Artemis Khatcherian; Inna Novitskaya; John A. Carucci; Reuven Bergman; James G. Krueger
J Immunol (2008) 181 (10): 7420–7427.
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Cover Image
Cover Image
On the cover: Cutaneous lesions in MRL-Faslpr mice (5 mo of age) resemble the verrucoid variant of human discoid lupus, characterized by interface vacuolar changes with apoptotic keratinocytes, acanthosis with hyperkeratosis/hypergranulosis and follicular plugging, and a superficial and deep lymphohistiocytic infiltrate with associated scarring alopecia (refer to Fig. 1 on page 7369; H&E, ×40). Menke, J., M.-Y. Hsu, K. T. Byrne, J. A. Lucas, W. A. Rabacal, B. P. Croker, X.-H. Zong, E. R. Stanley, and V. R. Kelley. 2008. Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Faslpr mice. J. Immunol. 181: 7367–7379.
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