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Detection of Complement Activation on Antigen Microarrays Generates Functional Antibody Profiles and Helps Characterization of Disease-Associated Changes of the Antibody Repertoire ¹

Krisztián Papp; Péter Végh; Kata Miklós; Julianna Németh; Klára Rásky; Ferenc Péterfy; Anna Erdei; József Prechl

J Immunol (2008) 181 (11): 8162–8169.

View articletitled, Detection of Complement Activation on Antigen Microarrays Generates Functional Antibody Profiles and Helps Characterization of Disease-Associated Changes of the Antibody Repertoire<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Resolution of Unique Sca-1^highc-Kit⁻ Lymphoid-Biased Progenitors in Adult Bone Marrow ¹

Benjamin C. Harman; Daniel L. Northrup; David Allman

J Immunol (2008) 181 (11): 7514–7524.

View articletitled, Resolution of Unique Sca-1<sup>high</sup>c-Kit<sup>−</sup> Lymphoid-Biased Progenitors in Adult Bone Marrow<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Magnitude of Thymic Output Is Genetically Determined through Controlled Intrathymic Precursor T Cell Proliferation ¹

Gaël Dulude; Remi Cheynier; Dominique Gauchat; Ali Abdallah; Nadia Kettaf; Rafick-Pierre Sékaly; Sophie Gratton

J Immunol (2008) 181 (11): 7818–7824.

View articletitled, The Magnitude of Thymic Output Is Genetically Determined through Controlled Intrathymic Precursor T Cell Proliferation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Members of the Staphylococcus aureus Extracellular Fibrinogen-Binding Protein Family Inhibit the Interaction of C3d with Complement Receptor 2 ¹

Daniel Ricklin; Salome K. Ricklin-Lichtsteiner; Maciej M. Markiewski; Brian V. Geisbrecht; John D. Lambris

J Immunol (2008) 181 (11): 7463–7467.

View articletitled, Cutting Edge: Members of the <em>Staphylococcus aureus</em> Extracellular Fibrinogen-Binding Protein Family Inhibit the Interaction of C3d with Complement Receptor 2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Requirement of IL-17RA in Con A Induced Hepatitis and Negative Regulation of IL-17 Production in Mouse T Cells

Takako Nagata; Laura Mckinley; Jacques J. Peschon; John F. Alcorn; Shean J. Aujla; Jay K. Kolls

J Immunol (2008) 181 (11): 7473–7479.

View articletitled, Requirement of IL-17RA in Con A Induced Hepatitis and Negative Regulation of IL-17 Production in Mouse T Cells

Supplementary data

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Persistence of Lung CD8 T Cell Oligoclonal Expansions upon Smoking Cessation in a Mouse Model of Cigarette Smoke-Induced Emphysema ¹

Gregory T. Motz; Bryan L. Eppert; Guangyun Sun; Scott C. Wesselkamper; Michael J. Linke; Ranjan Deka; Michael T. Borchers

J Immunol (2008) 181 (11): 8036–8043.

View articletitled, Persistence of Lung CD8 T Cell Oligoclonal Expansions upon Smoking Cessation in a Mouse Model of Cigarette Smoke-Induced Emphysema<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Coexpression of TGF-β1 and IL-10 Enables Regulatory T Cells to Completely Suppress Airway Hyperreactivity ¹

Katrin Presser; Dorothee Schwinge; Michael Wegmann; Samuel Huber; Steffen Schmitt; Alexander Quaas; Joachim H. Maxeiner; Susetta Finotto; Ansgar W. Lohse; Manfred Blessing; Christoph Schramm

J Immunol (2008) 181 (11): 7751–7758.

View articletitled, Coexpression of TGF-β1 and IL-10 Enables Regulatory T Cells to Completely Suppress Airway Hyperreactivity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Interaction between RANTES Promoter Variant and CCR5Δ32 Favors Recovery from Hepatitis B ¹

Chloe L. Thio; Jacquie Astemborski; Rasmi Thomas; Timothy Mosbruger; Mallory D. Witt; James J. Goedert; Keith Hoots; Cherie Winkler; David L. Thomas; Mary Carrington

J Immunol (2008) 181 (11): 7944–7947.

View articletitled, Interaction between <em>RANTES</em> Promoter Variant and <em>CCR5Δ32</em> Favors Recovery from Hepatitis B<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Targeting Poly(I:C) to the TLR3-Independent Pathway Boosts Effector CD8 T Cell Differentiation through IFN-α/β ¹

Soo M. Ngoi; Michael G. Tovey; Anthony T. Vella

J Immunol (2008) 181 (11): 7670–7680.

View articletitled, Targeting Poly(I:C) to the TLR3-Independent Pathway Boosts Effector CD8 T Cell Differentiation through IFN-α/β<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibition of the Alloimmune Response through the Generation of Regulatory T Cells by a MHC Class II-Derived Peptide ¹

Weiping Zang; Marvin Lin; Safa Kalache; Nan Zhang; Bernd Krüger; Ana Maria Waaga-Gasser; Martin Grimm; Wayne Hancock; Peter Heeger; Bernd Schröppel; Barbara Murphy

J Immunol (2008) 181 (11): 7499–7506.

View articletitled, Inhibition of the Alloimmune Response through the Generation of Regulatory T Cells by a MHC Class II-Derived Peptide<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation ¹

Suman Bandyopadhyay; Meixiao Long; Harry Z. Qui; Adam T. Hagymasi; Aaron M. Slaiby; Marianne A. Mihalyo; Hector L. Aguila; Robert S. Mittler; Anthony T. Vella; Adam J. Adler

J Immunol (2008) 181 (11): 7728–7737.

View articletitled, Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Protective Immunity to Systemic Infection with Attenuated Salmonella enterica serovar Enteritidis in the Absence of IL-12 Is Associated with IL-23-Dependent IL-22, but Not IL-17 ¹

Silke M. Schulz; Gabriele Köhler; Nicole Schütze; Jens Knauer; Reinhard K. Straubinger; Alissa A. Chackerian; Ellen Witte; Kerstin Wolk; Robert Sabat; Yoichiro Iwakura; Christoph Holscher; Uwe Müller; Robert A. Kastelein; Gottfried Alber

J Immunol (2008) 181 (11): 7891–7901.

View articletitled, Protective Immunity to Systemic Infection with Attenuated <em>Salmonella enterica</em> serovar Enteritidis in the Absence of IL-12 Is Associated with IL-23-Dependent IL-22, but Not IL-17<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lin⁻Sca1⁺Kit⁻ Bone Marrow Cells Contain Early Lymphoid-Committed Precursors That Are Distinct from Common Lymphoid Progenitors ¹

Ritu Kumar; Valentina Fossati; Mason Israel; Hans-Willem Snoeck

J Immunol (2008) 181 (11): 7507–7513.

View articletitled, Lin<sup>−</sup>Sca1<sup>+</sup>Kit<sup>−</sup> Bone Marrow Cells Contain Early Lymphoid-Committed Precursors That Are Distinct from Common Lymphoid Progenitors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity ¹

Joao Gamelas Magalhaes; Jörg H. Fritz; Lionel Le Bourhis; Gernot Sellge; Leonardo H. Travassos; Thirumahal Selvanantham; Stephen E. Girardin; Jennifer L. Gommerman; Dana J. Philpott

J Immunol (2008) 181 (11): 7925–7935.

View articletitled, Nod2-Dependent Th2 Polarization of Antigen-Specific Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Induction of A:T Mutations Is Dependent on Cellular Environment but Independent of Mutation Frequency and Target Gene Location

Akiko Ukai; Konomi Ishimaru; Rika Ouchida; Hiromi Mori; Chie Kano; Toshiyuki Moritan; Ji-Yang Wang

J Immunol (2008) 181 (11): 7835–7842.

View articletitled, Induction of A:T Mutations Is Dependent on Cellular Environment but Independent of Mutation Frequency and Target Gene Location

Supplementary data

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Abnormal Regulatory and Effector T Cell Function Predispose to Autoimmunity following Xenogeneic Thymic Transplantation ¹

Yasuhiro Fudaba; Takashi Onoe; Meredith Chittenden; Akira Shimizu; Juanita M. Shaffer; Roderick Bronson; Megan Sykes

J Immunol (2008) 181 (11): 7649–7659.

View articletitled, Abnormal Regulatory and Effector T Cell Function Predispose to Autoimmunity following Xenogeneic Thymic Transplantation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Intrarectal Vaccination with Recombinant Vaccinia Virus Expressing Carcinoembronic Antigen Induces Mucosal and Systemic Immunity and Prevents Progression of Colorectal Cancer ¹

Seunghee Kim-Schulze; Hong Sung Kim; Alberto Wainstein; Dae Won Kim; Wein Cui Yang; Dorota Moroziewicz; Phyllus Y. Mong; Michal Bereta; Bret Taback; Qin Wang; Howard L. Kaufman

J Immunol (2008) 181 (11): 8112–8119.

View articletitled, Intrarectal Vaccination with Recombinant Vaccinia Virus Expressing Carcinoembronic Antigen Induces Mucosal and Systemic Immunity and Prevents Progression of Colorectal Cancer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Enhanced T Cell Apoptosis within Drak2-Deficient Mice Promotes Resistance to Autoimmunity ¹

Stephanie J. Ramos; Jeniffer B. Hernandez; Martina Gatzka; Craig M. Walsh

J Immunol (2008) 181 (11): 7606–7616.

View articletitled, Enhanced T Cell Apoptosis within <em>Drak2</em>-Deficient Mice Promotes Resistance to Autoimmunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Targeting the Neonatal Fc Receptor for Antigen Delivery Using Engineered Fc Fragments ¹

Wentao Mi; Sylvia Wanjie; Su-Tang Lo; Zhuo Gan; Beatrix Pickl-Herk; Raimund J. Ober; E. Sally Ward

J Immunol (2008) 181 (11): 7550–7561.

View articletitled, Targeting the Neonatal Fc Receptor for Antigen Delivery Using Engineered Fc Fragments<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MHC Class II Presentation of gp100 Epitopes in Melanoma Cells Requires the Function of Conventional Endosomes and Is Influenced by Melanosomes ¹

Valentina Robila; Marina Ostankovitch; Michelle L. Altrich-VanLith; Alexander C. Theos; Sheila Drover; Michael S. Marks; Nicholas Restifo; Victor H. Engelhard

J Immunol (2008) 181 (11): 7843–7852.

View articletitled, MHC Class II Presentation of gp100 Epitopes in Melanoma Cells Requires the Function of Conventional Endosomes and Is Influenced by Melanosomes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibitors of TLR8 Reduce TNF Production from Human Rheumatoid Synovial Membrane Cultures ¹

Sandra M. Sacre; Alexandra Lo; Bernard Gregory; Rachel E. Simmonds; Lynn Williams; Marc Feldmann; Fionula M. Brennan; Brian M. Foxwell

J Immunol (2008) 181 (11): 8002–8009.

View articletitled, Inhibitors of TLR8 Reduce TNF Production from Human Rheumatoid Synovial Membrane Cultures<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells ¹

Hye Sun Kuehn; Emily J. Swindle; Mi-Sun Kim; Michael A. Beaven; Dean D. Metcalfe; Alasdair M. Gilfillan

J Immunol (2008) 181 (11): 7706–7712.

View articletitled, The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Promiscuous Interaction between Gold-Specific T Cells and APCs in Gold Allergy ¹

Hideo Hashizume; Naohiro Seo; Taisuke Ito; Masahiro Takigawa; Hiroaki Yagi

J Immunol (2008) 181 (11): 8096–8102.

View articletitled, Promiscuous Interaction between Gold-Specific T Cells and APCs in Gold Allergy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: Selective Blockade of LIGHT-Lymphotoxin β Receptor Signaling Protects Mice from Experimental Cerebral Malaria Caused by Plasmodium berghei ANKA

Louise M. Randall; Fiona H. Amante; Yonghong Zhou; Amanda C. Stanley; Ashraful Haque; Fabian Rivera; Klaus Pfeffer; Stefanie Scheu; Geoff R. Hill; Koji Tamada; Christian R. Engwerda

J Immunol (2008) 181 (11): 7458–7462.

View articletitled, Cutting Edge: Selective Blockade of LIGHT-Lymphotoxin β Receptor Signaling Protects Mice from Experimental Cerebral Malaria Caused by <em>Plasmodium berghei</em> ANKA

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Restoration of Adenosine Deaminase-Deficient Human Thymocyte Development In Vitro by Inhibition of Deoxynucleoside Kinases ¹^²

Michelle L. Joachims; Patrick A. Marble; Aletha B. Laurent; Peter Pastuszko; Marco Paliotta; Michael R. Blackburn; Linda F. Thompson

J Immunol (2008) 181 (11): 8153–8161.

View articletitled, Restoration of Adenosine Deaminase-Deficient Human Thymocyte Development In Vitro by Inhibition of Deoxynucleoside Kinases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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The Role of Thymic Stromal Lymphopoietin in CD8⁺ T Cell Homeostasis ¹

Yrina Rochman; Warren J. Leonard

J Immunol (2008) 181 (11): 7699–7705.

View articletitled, The Role of Thymic Stromal Lymphopoietin in CD8<sup>+</sup> T Cell Homeostasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dynamic Modulation of CCR7 Expression and Function on Naive T Lymphocytes In Vivo ¹

Mirjam R. Britschgi; Alexander Link; Tonje Katrine A. Lissandrin; Sanjiv A. Luther

J Immunol (2008) 181 (11): 7681–7688.

View articletitled, Dynamic Modulation of CCR7 Expression and Function on Naive T Lymphocytes In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Retinoic Acids Are Potent Inhibitors of Spontaneous Human Eosinophil Apoptosis

Shigeharu Ueki; Gulixian Mahemuti; Hajime Oyamada; Hikari Kato; Junko Kihara; Masako Tanabe; Wataru Ito; Takahito Chiba; Masahide Takeda; Hiroyuki Kayaba; Junichi Chihara

J Immunol (2008) 181 (11): 7689–7698.

View articletitled, Retinoic Acids Are Potent Inhibitors of Spontaneous Human Eosinophil Apoptosis

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OX40 Drives Protective Vaccinia Virus-Specific CD8 T Cells ¹^²

Shahram Salek-Ardakani; Magdalini Moutaftsi; Shane Crotty; Alessandro Sette; Michael Croft

J Immunol (2008) 181 (11): 7969–7976.

View articletitled, OX40 Drives Protective Vaccinia Virus-Specific CD8 T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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T Cell-Independent Spontaneous Loss of Tolerance by Anti-Double-Stranded DNA B Cells in C57BL/6 Mice ¹

Patricia Y. Tsao; Jing Jiao; Mei Qing Ji; Philip L. Cohen; Robert A. Eisenberg

J Immunol (2008) 181 (11): 7770–7777.

View articletitled, T Cell-Independent Spontaneous Loss of Tolerance by Anti-Double-Stranded DNA B Cells in C57BL/6 Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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NK Cells Induce Apoptosis in Tubular Epithelial Cells and Contribute to Renal Ischemia-Reperfusion Injury ¹

Zhu-Xu Zhang; Shuang Wang; Xuyan Huang; Wei-Ping Min; Hongtao Sun; Weihua Liu; Bertha Garcia; Anthony M. Jevnikar

J Immunol (2008) 181 (11): 7489–7498.

View articletitled, NK Cells Induce Apoptosis in Tubular Epithelial Cells and Contribute to Renal Ischemia-Reperfusion Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Factor C Acts as a Lipopolysaccharide-Responsive C3 Convertase in Horseshoe Crab Complement Activation ¹^²

Shigeru Ariki; Shusaku Takahara; Toshio Shibata; Takaaki Fukuoka; Aya Ozaki; Yuichi Endo; Teizo Fujita; Takumi Koshiba; Shun-ichiro Kawabata

J Immunol (2008) 181 (11): 7994–8001.

View articletitled, Factor C Acts as a Lipopolysaccharide-Responsive C3 Convertase in Horseshoe Crab Complement Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

Supplementary data

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CD40-Induced Signaling in Human Endothelial Cells Results in mTORC2- and Akt-Dependent Expression of Vascular Endothelial Growth Factor In Vitro and In Vivo ¹

Olivier Dormond; Alan G. Contreras; Esther Meijer; Dipak Datta; Evelyn Flynn; Soumitro Pal; David M. Briscoe

J Immunol (2008) 181 (11): 8088–8095.

View articletitled, CD40-Induced Signaling in Human Endothelial Cells Results in mTORC2- and Akt-Dependent Expression of Vascular Endothelial Growth Factor In Vitro and In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Rapid Deletion of Antigen-Specific CD4⁺ T Cells following Infection Represents a Strategy of Immune Evasion and Persistence for Anaplasma marginale¹

Sushan Han; Junzo Norimine; Guy H. Palmer; Waithaka Mwangi; Kevin K. Lahmers; Wendy C. Brown

J Immunol (2008) 181 (11): 7759–7769.

View articletitled, Rapid Deletion of Antigen-Specific CD4<sup>+</sup> T Cells following Infection Represents a Strategy of Immune Evasion and Persistence for <em>Anaplasma marginale</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Number of Respiratory Syncytial Virus (RSV)-Specific Memory CD8 T Cells in the Lung Is Critical for Their Ability to Inhibit RSV Vaccine-Enhanced Pulmonary Eosinophilia ¹

Matthew R. Olson; Stacey M. Hartwig; Steven M. Varga

J Immunol (2008) 181 (11): 7958–7968.

View articletitled, The Number of Respiratory Syncytial Virus (RSV)-Specific Memory CD8 T Cells in the Lung Is Critical for Their Ability to Inhibit RSV Vaccine-Enhanced Pulmonary Eosinophilia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Multidrug Resistance-Associated Transporter 2 Regulates Mucosal Inflammation by Facilitating the Synthesis of Hepoxilin A₃ ¹

Michael Pazos; Dario Siccardi; Karen L. Mumy; Jeffrey D. Bien; Steve Louie; Hai Ning Shi; Karsten Gronert; Randall J. Mrsny; Beth A. McCormick

J Immunol (2008) 181 (11): 8044–8052.

View articletitled, Multidrug Resistance-Associated Transporter 2 Regulates Mucosal Inflammation by Facilitating the Synthesis of Hepoxilin A<sub>3</sub><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Increased Osteopontin Expression in Dendritic Cells Amplifies IL-17 Production by CD4⁺ T Cells in Experimental Autoimmune Encephalomyelitis and in Multiple Sclerosis ¹

Gopal Murugaiyan; Akanksha Mittal; Howard L. Weiner

J Immunol (2008) 181 (11): 7480–7488.

View articletitled, Increased Osteopontin Expression in Dendritic Cells Amplifies IL-17 Production by CD4<sup>+</sup> T Cells in Experimental Autoimmune Encephalomyelitis and in Multiple Sclerosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Migration of Langerhans Dendritic Cells Is Impaired in Autoimmune Dermatitis ¹

Anna U. Eriksson; Ram Raj Singh

J Immunol (2008) 181 (11): 7468–7472.

View articletitled, Cutting Edge: Migration of Langerhans Dendritic Cells Is Impaired in Autoimmune Dermatitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: Viral Infection Breaks NK Cell Tolerance to “Missing Self”¹

Joseph C. Sun; Lewis L. Lanier

J Immunol (2008) 181 (11): 7453–7457.

View articletitled, Cutting Edge: Viral Infection Breaks NK Cell Tolerance to “Missing Self”<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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RGS13 Controls G Protein-Coupled Receptor-Evoked Responses of Human Mast Cells ¹

Geetanjali Bansal; Jeffrey A. DiVietro; Hye Sun Kuehn; Sudhir Rao; Karl H. Nocka; Alasdair M. Gilfillan; Kirk M. Druey

J Immunol (2008) 181 (11): 7882–7890.

View articletitled, RGS13 Controls G Protein-Coupled Receptor-Evoked Responses of Human Mast Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Egr2 Is Required for Bcl-2 Induction during Positive Selection ¹

Jens-Peter Holst Lauritsen; Sridevi Kurella; Sang-Yun Lee; Juliette M. Lefebvre; Michele Rhodes; José Alberola-Ila; David L. Wiest

J Immunol (2008) 181 (11): 7778–7785.

View articletitled, Egr2 Is Required for Bcl-2 Induction during Positive Selection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Photoaffinity Antigens for Human γδ T Cells ¹

Ghanashyam Sarikonda; Hong Wang; Kia-Joo Puan; Xiao-hui Liu; Hoi K. Lee; Yongcheng Song; Mark D. Distefano; Eric Oldfield; Glenn D. Prestwich; Craig T. Morita

J Immunol (2008) 181 (11): 7738–7750.

View articletitled, Photoaffinity Antigens for Human γδ T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

Dominik Hartl; Susanne Krauss-Etschmann; Barbara Koller; Peter L. Hordijk; Taco W. Kuijpers; Florian Hoffmann; Andreas Hector; Ernst Eber; Veronica Marcos; Iris Bittmann; Oliver Eickelberg; Matthias Griese; Dirk Roos

J Immunol (2008) 181 (11): 8053–8067.

View articletitled, Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

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Transgenic Expression of Cyclooxygenase-2 in Hepatocytes Accelerates Endotoxin-Induced Acute Liver Failure ¹

Chang Han; Guiying Li; Kyu Lim; Marie C. DeFrances; Chandrashekhar R. Gandhi; Tong Wu

J Immunol (2008) 181 (11): 8027–8035.

View articletitled, Transgenic Expression of Cyclooxygenase-2 in Hepatocytes Accelerates Endotoxin-Induced Acute Liver Failure<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1

C. S. McKimmie; A. R. Fraser; C. Hansell; L. Gutiérrez; S. Philipsen; L. Connell; A. Rot; M. Kurowska-Stolarska; P. Carreno; M. Pruenster; C.-C. Chu; G. Lombardi; C. Halsey; I. B. McInnes; F. Y. Liew; R. J. Nibbs; G. J. Graham

J Immunol (2008) 181 (11): 8170–8181.

View articletitled, Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1

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Cutting Edge: The Idd3 Genetic Interval Determines Regulatory T Cell Function through CD11b⁺CD11c⁻ APC ¹

Ana C. Anderson; Rucha Chandwaskar; David H. Lee; Vijay K. Kuchroo

J Immunol (2008) 181 (11): 7449–7452.

View articletitled, Cutting Edge: The <em>Idd3</em> Genetic Interval Determines Regulatory T Cell Function through CD11b<sup>+</sup>CD11c<sup>−</sup> APC<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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SOCS1 Regulates the IFN but Not NFκB Pathway in TLR-Stimulated Human Monocytes and Macrophages ¹

Cecilia M. Prêle; Eleanor A. Woodward; Jacqueline Bisley; April Keith-Magee; Sandra E. Nicholson; Prue H. Hart

J Immunol (2008) 181 (11): 8018–8026.

View articletitled, SOCS1 Regulates the IFN but Not NFκB Pathway in TLR-Stimulated Human Monocytes and Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Secretion and Uptake of Lysosomal Phospholipase A₂ by Alveolar Macrophages ¹

Akira Abe; Robert Kelly; Jessica Kollmeyer; Miki Hiraoka; Ye Lu; James A. Shayman

J Immunol (2008) 181 (11): 7873–7881.

View articletitled, The Secretion and Uptake of Lysosomal Phospholipase A<sub>2</sub> by Alveolar Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mucosal Clearance of Capsule-Expressing Bacteria Requires Both TLR and Nucleotide-Binding Oligomerization Domain 1 Signaling ¹

Tracey A. Zola; Elena S. Lysenko; Jeffrey N. Weiser

J Immunol (2008) 181 (11): 7909–7916.

View articletitled, Mucosal Clearance of Capsule-Expressing Bacteria Requires Both TLR and Nucleotide-Binding Oligomerization Domain 1 Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Enhancement in Specific CD8⁺ T Cell Recognition of EphA2⁺ Tumors In Vitro and In Vivo after Treatment with Ligand Agonists ¹

Amy K. Wesa; Christopher J. Herrem; Maja Mandic; Jennifer L. Taylor; Cecilia Vasquez; Mayumi Kawabe; Tomohide Tatsumi; Michael S. Leibowitz; James H. Finke; Ronald M. Bukowski; Elizabeth Bruckheimer; Michael S. Kinch; Walter J. Storkus

J Immunol (2008) 181 (11): 7721–7727.

View articletitled, Enhancement in Specific CD8<sup>+</sup> T Cell Recognition of EphA2<sup>+</sup> Tumors In Vitro and In Vivo after Treatment with Ligand Agonists<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification of Human T Cell Antigens for the Development of Vaccines against Mycobacterium tuberculosis¹

Sylvie Bertholet; Gregory C. Ireton; Maria Kahn; Jeffrey Guderian; Raodoh Mohamath; Nicole Stride; Elsa M. Laughlin; Susan L. Baldwin; Thomas S. Vedvick; Rhea N. Coler; Steven G. Reed

J Immunol (2008) 181 (11): 7948–7957.

View articletitled, Identification of Human T Cell Antigens for the Development of Vaccines against <em>Mycobacterium tuberculosis</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Multimerization of Surfactant Protein D, but Not Its Collagen Domain, Is Required for Antiviral and Opsonic Activities Related to Influenza Virus ¹

Mitchell White; Paul Kingma; Tesfaldet Tecle; Nilgun Kacak; Bruce Linders; John Heuser; Erika Crouch; Kevan Hartshorn

J Immunol (2008) 181 (11): 7936–7943.

View articletitled, Multimerization of Surfactant Protein D, but Not Its Collagen Domain, Is Required for Antiviral and Opsonic Activities Related to Influenza Virus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dysregulation of CXCR3 Signaling due to CXCL10 Deficiency Impairs the Antiviral Response to Herpes Simplex Virus 1 Infection ¹

Todd R. Wuest; Daniel J. J. Carr

J Immunol (2008) 181 (11): 7985–7993.

View articletitled, Dysregulation of CXCR3 Signaling due to CXCL10 Deficiency Impairs the Antiviral Response to Herpes Simplex Virus 1 Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: CD4⁺ T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8⁺ T Cell Responses ¹

Elizabeth B. Wilson; Alexandra M. Livingstone

J Immunol (2008) 181 (11): 7445–7448.

View articletitled, Cutting Edge: CD4<sup>+</sup> T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8<sup>+</sup> T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TREM-2 Mediated Signaling Induces Antigen Uptake and Retention in Mature Myeloid Dendritic Cells ¹

Suresh Radhakrishnan; Laura N. Arneson; Jadee L. Upshaw; Charles L. Howe; Sara J. Felts; Marco Colonna; Paul J. Leibson; Moses Rodriguez; Larry R. Pease

J Immunol (2008) 181 (11): 7863–7872.

View articletitled, TREM-2 Mediated Signaling Induces Antigen Uptake and Retention in Mature Myeloid Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An In Vitro System to Model the Establishment and Reactivation of HIV-1 Latency

Alessandra Marini; Jill M. Harper; Fabio Romerio

J Immunol (2008) 181 (11): 7713–7720.

View articletitled, An In Vitro System to Model the Establishment and Reactivation of HIV-1 Latency

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TCR β-Chain Sharing in Human CD8⁺ T Cell Responses to Cytomegalovirus and EBV ¹

Vanessa Venturi; Hui Yee Chin; Tedi E. Asher; Kristin Ladell; Phillip Scheinberg; Ethan Bornstein; David van Bockel; Anthony D. Kelleher; Daniel C. Douek; David A. Price; Miles P. Davenport

J Immunol (2008) 181 (11): 7853–7862.

View articletitled, TCR β-Chain Sharing in Human CD8<sup>+</sup> T Cell Responses to Cytomegalovirus and EBV<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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IN THIS ISSUE

J Immunol (2008) 181 (11): 7433–7434.

View articletitled, IN THIS ISSUE

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Pillars Article: Generation of T-cell Function in Organ Culture of Foetal Mouse Thymus. I. Mitogen Responsiveness

J. H. Robinson; J. J. T. Owen

J Immunol (2008) 181 (11): 7437–7444.

View articletitled, Pillars Article: Generation of T-cell Function in Organ Culture of Foetal Mouse Thymus. I. Mitogen Responsiveness

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Binding of Rituximab, Trastuzumab, Cetuximab, or mAb T101 to Cancer Cells Promotes Trogocytosis Mediated by THP-1 Cells and Monocytes ¹

Paul V. Beum; David A. Mack; Andrew W. Pawluczkowycz; Margaret A. Lindorfer; Ronald P. Taylor

J Immunol (2008) 181 (11): 8120–8132.

View articletitled, Binding of Rituximab, Trastuzumab, Cetuximab, or mAb T101 to Cancer Cells Promotes Trogocytosis Mediated by THP-1 Cells and Monocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TCR Down-Regulation Controls Virus-Specific CD8⁺ T Cell Responses ¹

Charlotte Menné Bonefeld; Mariëlle Haks; Bodil Nielsen; Marina von Essen; Lasse Boding; Ann Kathrine Hansen; Jeppe Madura Larsen; Niels Ødum; Paul Krimpenfort; Ada Kruisbeek; Jan Pravsgaard Christensen; Allan Randrup Thomsen; Carsten Geisler

J Immunol (2008) 181 (11): 7786–7799.

View articletitled, TCR Down-Regulation Controls Virus-Specific CD8<sup>+</sup> T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Uncoupling of Induced Protein Processing from Maturation in Dendritic Cells Exposed to a Highly Antigenic Preparation from a Helminth Parasite ¹

Fraser A. Marshall; Edward J. Pearce

J Immunol (2008) 181 (11): 7562–7570.

View articletitled, Uncoupling of Induced Protein Processing from Maturation in Dendritic Cells Exposed to a Highly Antigenic Preparation from a Helminth Parasite<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Deregulation of c-Myc Confers Distinct Survival Requirements for Memory B Cells, Plasma Cells, and Their Progenitors ¹

Sefat E. Khuda; William M. Loo; Siegfried Janz; Brian Van Ness; Loren D. Erickson

J Immunol (2008) 181 (11): 7537–7549.

View articletitled, Deregulation of c-Myc Confers Distinct Survival Requirements for Memory B Cells, Plasma Cells, and Their Progenitors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Expression and Molecular Associations of Syk in Systemic Lupus Erythematosus T Cells ¹

Sandeep Krishnan; Yuang-Taung Juang; Bhabadeb Chowdhury; Abigail Magilavy; Carolyn U. Fisher; Hang Nguyen; Madhusoodana P. Nambiar; Vasileios Kyttaris; Arthur Weinstein; Rena Bahjat; Polly Pine; Violeta Rus; George C. Tsokos

J Immunol (2008) 181 (11): 8145–8152.

View articletitled, Differential Expression and Molecular Associations of Syk in Systemic Lupus Erythematosus T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells ¹

Sae-Bom Jeon; Hee Jung Yoon; Se-Ho Park; In-Hoo Kim; Eun Jung Park

J Immunol (2008) 181 (11): 8077–8087.

View articletitled, Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Aging Mice Exhibit a Functional Defect in Mucosal Dendritic Cell Response against an Intracellular Pathogen ¹

Magali M. Moretto; Elizabeth M. Lawlor; Imtiaz A. Khan

J Immunol (2008) 181 (11): 7977–7984.

View articletitled, Aging Mice Exhibit a Functional Defect in Mucosal Dendritic Cell Response against an Intracellular Pathogen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Transplantation of Bone Marrow Transduced to Express Self-Antigen Establishes Deletional Tolerance and Permanently Remits Autoimmune Disease ¹

James Chan; Ee Jun Ban; Keng Hao Chun; Shunhe Wang; B. Thomas Bäckström; Claude C. A. Bernard; Ban-Hock Toh; Frank Alderuccio

J Immunol (2008) 181 (11): 7571–7580.

View articletitled, Transplantation of Bone Marrow Transduced to Express Self-Antigen Establishes Deletional Tolerance and Permanently Remits Autoimmune Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Retinal Pigment Epithelium-Derived CTLA-2α Induces TGFβ-Producing T Regulatory Cells ¹^²

Sunao Sugita; Shintaro Horie; Orie Nakamura; Yuri Futagami; Hiroshi Takase; Hiroshi Keino; Hiroyuki Aburatani; Nobuhiko Katunuma; Kazumi Ishidoh; Yoshimi Yamamoto; Manabu Mochizuki

J Immunol (2008) 181 (11): 7525–7536.

View articletitled, Retinal Pigment Epithelium-Derived CTLA-2α Induces TGFβ-Producing T Regulatory Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Signals and Sequences That Control CD28 Localization to the Central Region of the Immunological Synapse ¹

Mariano Sanchez-Lockhart; Beth Graf; Jim Miller

J Immunol (2008) 181 (11): 7639–7648.

View articletitled, Signals and Sequences That Control CD28 Localization to the Central Region of the Immunological Synapse<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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In Vivo BLyS/BAFF Neutralization Ameliorates Islet-Directed Autoimmunity in Nonobese Diabetic Mice ¹

Ghazal Zekavat; Susan Y. Rostami; Armen Badkerhanian; Ronald F. Parsons; Brigitte Koeberlein; Ming Yu; Christopher D. Ward; Thi-Sau Migone; Liping Yu; George S. Eisenbarth; Michael P. Cancro; Ali Naji; Hooman Noorchashm

J Immunol (2008) 181 (11): 8133–8144.

View articletitled, In Vivo BLyS/BAFF Neutralization Ameliorates Islet-Directed Autoimmunity in Nonobese Diabetic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel Targeted Inhibitor of the Alternative Pathway of Complement and Its Therapeutic Application in Ischemia/Reperfusion Injury ¹

Yuxiang Huang; Fei Qiao; Carl Atkinson; V. Michael Holers; Stephen Tomlinson

J Immunol (2008) 181 (11): 8068–8076.

View articletitled, A Novel Targeted Inhibitor of the Alternative Pathway of Complement and Its Therapeutic Application in Ischemia/Reperfusion Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complement Receptor of the Ig Superfamily Enhances Complement-Mediated Phagocytosis in a Subpopulation of Tissue Resident Macrophages

Nick N. Gorgani; Jeannie Q. He; Kenneth J. Katschke, Jr.; Karim Y. Helmy; Hongkang Xi; Micah Steffek; Philip E. Hass; Menno van Lookeren Campagne

J Immunol (2008) 181 (11): 7902–7908.

View articletitled, Complement Receptor of the Ig Superfamily Enhances Complement-Mediated Phagocytosis in a Subpopulation of Tissue Resident Macrophages

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Deficiency of HIV-Gag-Specific T Cells in Early Childhood Correlates with Poor Viral Containment ¹

SiHong Huang; Jacqueline Dunkley-Thompson; YanHua Tang; Eric A. Macklin; Julianne Steel-Duncan; Indira Singh-Minott; Elizabeth G. Ryland; Monica Smikle; Bruce D. Walker; Celia D. C. Christie; Margaret E. Feeney

J Immunol (2008) 181 (11): 8103–8111.

View articletitled, Deficiency of HIV-Gag-Specific T Cells in Early Childhood Correlates with Poor Viral Containment<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Granzyme C Supports Efficient CTL-Mediated Killing Late in Primary Alloimmune Responses ¹

Yonas Getachew; Heather Stout-Delgado; Bonnie C. Miller; Dwain L. Thiele

J Immunol (2008) 181 (11): 7810–7817.

View articletitled, Granzyme C Supports Efficient CTL-Mediated Killing Late in Primary Alloimmune Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel IFN Regulatory Factor 3-Dependent Pathway Activated by Trypanosomes Triggers IFN-β in Macrophages and Fibroblasts ¹

Anne-Danielle C. Chessler; Ludmila R. P. Ferreira; Tun-Han Chang; Katherine A. Fitzgerald; Barbara A. Burleigh

J Immunol (2008) 181 (11): 7917–7924.

View articletitled, A Novel IFN Regulatory Factor 3-Dependent Pathway Activated by Trypanosomes Triggers IFN-β in Macrophages and Fibroblasts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Drak2 Regulates the Survival of Activated T Cells and Is Required for Organ-Specific Autoimmune Disease ¹

Maureen A. McGargill; Carmen Choy; Ben G. Wen; Stephen M. Hedrick

J Immunol (2008) 181 (11): 7593–7605.

View articletitled, Drak2 Regulates the Survival of Activated T Cells and Is Required for Organ-Specific Autoimmune Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Immunosuppressor Mycophenolic Acid Kills Activated Lymphocytes by Inducing a Nonclassical Actin-Dependent Necrotic Signal ¹

Benjamin Chaigne-Delalande; Gwendaline Guidicelli; Lionel Couzi; Pierre Merville; Walid Mahfouf; Stéphane Bouchet; Mathieu Molimard; Benoit Pinson; Jean-François Moreau; Patrick Legembre

J Immunol (2008) 181 (11): 7630–7638.

View articletitled, The Immunosuppressor Mycophenolic Acid Kills Activated Lymphocytes by Inducing a Nonclassical Actin-Dependent Necrotic Signal<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A New Approach to the Blocking of Alloreactive T Cell-Mediated Graft-versus-Host Disease by In Vivo Administration of Anti-CXCR3 Neutralizing Antibody ¹

Shan He; Qi Cao; Yuhua Qiu; Jianqing Mi; Jingwu Z. Zhang; Min Jin; Hailiang Ge; Stephen G. Emerson; Yi Zhang; Yanyun Zhang

J Immunol (2008) 181 (11): 7581–7592.

View articletitled, A New Approach to the Blocking of Alloreactive T Cell-Mediated Graft-versus-Host Disease by In Vivo Administration of Anti-CXCR3 Neutralizing Antibody<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-33 induced Ag-specific IL-5⁺ T cells and promotes allergic-induced airway inflammation independent of IL-4

M. Kurowska-Stolarska; P. Kewin; G. Murphy; R. C. Russo; B. Stolarski; C. C. Garcia; M. Komai-Koma; N. Pitman; Y. Li; A. N. J. McKenzie; M. M. Teixeira; F. Y. Liew; D. Xu

J Immunol (2008) 181 (11): 8170.

View articletitled, IL-33 induced Ag-specific IL-5<sup>+</sup> T cells and promotes allergic-induced airway inflammation independent of IL-4

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Bringing the Thymus to the Bench

Graham Anderson; Eric J. Jenkinson

J Immunol (2008) 181 (11): 7435–7436.

View articletitled, Bringing the Thymus to the Bench

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Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis ¹

Wen-Qi Lai; Anastasia Windy Irwan; Hong Heng Goh; Hwee Siew Howe; David T. Yu; Rafael Valle-Oñate; Iain B. McInnes; Alirio J. Melendez; Bernard P. Leung

J Immunol (2008) 181 (11): 8010–8017.

View articletitled, Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Erk2 MAPK Regulates CD8 T Cell Proliferation and Survival ¹

Warren N. D'Souza; Chiung-Fang Chang; April M. Fischer; Manqing Li; Stephen M. Hedrick

J Immunol (2008) 181 (11): 7617–7629.

View articletitled, The Erk2 MAPK Regulates CD8 T Cell Proliferation and Survival<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TNF Receptor-Associated Factor 5 Is Required for Optimal T Cell Expansion and Survival in Response to Infection ¹

Zachary J. Kraus; Jodie S. Haring; Gail A. Bishop

J Immunol (2008) 181 (11): 7800–7809.

View articletitled, TNF Receptor-Associated Factor 5 Is Required for Optimal T Cell Expansion and Survival in Response to Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An Activation-Induced Cytidine Deaminase-Independent Mechanism of Secondary V_H Gene Rearrangement in Preimmune Human B Cells ¹

Nancy S. Longo; Gabrielle J. Grundy; Jisoo Lee; Martin Gellert; Peter E. Lipsky

J Immunol (2008) 181 (11): 7825–7834.

View articletitled, An Activation-Induced Cytidine Deaminase-Independent Mechanism of Secondary V<sub>H</sub> Gene Rearrangement in Preimmune Human B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Galectin-9 Increases Tim-3⁺ Dendritic Cells and CD8⁺ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions ¹

Keiko Nagahara; Tomohiro Arikawa; Souichi Oomizu; Keiichi Kontani; Atsuya Nobumoto; Hiroaki Tateno; Kota Watanabe; Toshiro Niki; Shigeki Katoh; Minoru Miyake; Syun-Ichiro Nagahata; Jun Hirabayashi; Vijay K. Kuchroo; Akira Yamauchi; Mitsuomi Hirashima

J Immunol (2008) 181 (11): 7660–7669.

View articletitled, Galectin-9 Increases Tim-3<sup>+</sup> Dendritic Cells and CD8<sup>+</sup> T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cover Image

Cover Image

On the cover: Langerhans dendritic cells in the skin. Immunofluorescence staining of MHC class II (green) and langerin (blue) in epidermal sheets freshly isolated from the ear skin of a normal adult mouse. Confocal images show that all MHCII⁺ cells in the epidermis express langerin and are called Langerhans cells. Eriksson, A. U., and R. R. Singh. 2008. Cutting Edge: Migration of Langerhans dendritic cells is impaired in autoimmune dermatitis. J. Immunol. 181: 7468–7472.
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