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Reprogrammed FoxP3+ T Regulatory Cells Become IL-17+ Antigen-Specific Autoimmune Effectors In Vitro and In Vivo1
Suresh Radhakrishnan; Rosalyn Cabrera; Erin L. Schenk; Pilar Nava-Parada; Michael P. Bell; Virginia P. Van Keulen; Ronald J. Marler; Sara J. Felts; Larry R. Pease
J Immunol (2008) 181 (5): 3137–3147.
Tissue-Type Plasminogen Activator Is a Regulator of Monocyte Diapedesis through the Brain Endothelial Barrier1
Arie Reijerkerk; Gijs Kooij; Susanne M. A. van der Pol; Thomas Leyen; Bert van het Hof; Pierre-Olivier Couraud; Denis Vivien; Christine D. Dijkstra; Helga E. de Vries
J Immunol (2008) 181 (5): 3567–3574.
Chronic Lymphocytic Leukemia Cells Bind and Present the Erythrocyte Protein Band 3: Possible Role as Initiators of Autoimmune Hemolytic Anemia1
Jeremías Galletti; Cristian Cañones; Pablo Morande; Mercedes Borge; Pablo Oppezzo; Jorge Geffner; Raimundo Bezares; Romina Gamberale; Mirta Giordano
J Immunol (2008) 181 (5): 3674–3683.
A Polypyrimidine Tract-Binding Protein-Dependent Pathway of mRNA Stability Initiates with CpG Activation of Primary B Cells1
J Immunol (2008) 181 (5): 3336–3345.
Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway1
Emilia Mira; Beatriz León; Domingo F. Barber; Sonia Jiménez-Baranda; Iñigo Goya; Luis Almonacid; Gabriel Márquez; Angel Zaballos; Carlos Martínez-A.; Jens V. Stein; Carlos Ardavín; Santos Mañes
J Immunol (2008) 181 (5): 3524–3534.
IL-17A Produced by γδ T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver1
Satoru Hamada; Masayuki Umemura; Takeru Shiono; Kensho Tanaka; Ayano Yahagi; M. Dilara Begum; Kiyotetsu Oshiro; Yuko Okamoto; Hisami Watanabe; Kazuyoshi Kawakami; Christina Roark; Willi K. Born; Rebecca O'Brien; Koichi Ikuta; Hiromichi Ishikawa; Susumu Nakae; Yoichiro Iwakura; Takao Ohta; Goro Matsuzaki
J Immunol (2008) 181 (5): 3456–3463.
Increased Regulatory versus Effector T Cell Development Is Associated with Thymus Atrophy in Mouse Models of Multiple Myeloma1
J Immunol (2008) 181 (5): 3714–3724.
Adoptive Transfer of Gene-Modified Primary NK Cells Can Specifically Inhibit Tumor Progression In Vivo1
J Immunol (2008) 181 (5): 3449–3455.
Neutrophil Apoptosis: Selective Regulation by Different Ligands of Integrin αMβ21
J Immunol (2008) 181 (5): 3609–3619.
Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells1
Satoko Matsumura; Baomei Wang; Noriko Kawashima; Steve Braunstein; Michelle Badura; Thomas O. Cameron; James S. Babb; Robert J. Schneider; Silvia C. Formenti; Michael L. Dustin; Sandra Demaria
J Immunol (2008) 181 (5): 3099–3107.
Human Anti-IgG1 Hinge Autoantibodies Reconstitute the Effector Functions of Proteolytically Inactivated IgGs1
Randall J. Brezski; Jennifer L. Luongo; Diane Petrone; Mary H. Ryan; Degang Zhong; Susan H. Tam; Albert P. Schmidt; Marian Kruszynski; Brian P. Whitaker; David M. Knight; Robert E. Jordan
J Immunol (2008) 181 (5): 3183–3192.
Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp41
Julie M. Fletcher; Margaret A. Jordan; Sarah L. Snelgrove; Robyn M. Slattery; François D. Dufour; Konstantinos Kyparissoudis; Gurdyal S. Besra; Dale I. Godfrey; Alan G. Baxter
J Immunol (2008) 181 (5): 3400–3412.
Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA11
Clive S. McKimmie; Alasdair R. Fraser; Chris Hansell; Laura Gutiérrez; Sjaak Philipsen; Laura Connell; Antal Rot; Mariola Kurowska-Stolarska; Paz Carreno; Monika Pruenster; Chung-Ching Chu; Giovanna Lombardi; Christina Halsey; Iain B. McInnes; Foo Y. Liew; Robert J. Nibbs; Gerard J. Graham
J Immunol (2008) 181 (5): 3353–3363.
Expression and Functional Significance of SOCS-1 and SOCS-3 in Astrocytes1
J Immunol (2008) 181 (5): 3167–3176.
Targeting CpG Oligonucleotides to the Lymph Node by Nanoparticles Elicits Efficient Antitumoral Immunity1
Carole Bourquin; David Anz; Klaus Zwiorek; Anna-Lisa Lanz; Sebastian Fuchs; Sarah Weigel; Cornelia Wurzenberger; Philip von der Borch; Michaela Golic; Stefan Moder; Gerhard Winter; Conrad Coester; Stefan Endres
J Immunol (2008) 181 (5): 2990–2998.
PKCβΙΙ Augments NF-κB-Dependent Transcription at the CCL11 Promoter via p300/CBP-Associated Factor Recruitment and Histone H4 Acetylation1
J Immunol (2008) 181 (5): 3503–3514.
Two Macrophage Colony-Stimulating Factor Genes Exist in Fish That Differ in Gene Organization and Are Differentially Expressed12
J Immunol (2008) 181 (5): 3310–3322.
Inhalation of Staphylococcus aureus Enterotoxin A Induces IFN-γ and CD8 T Cell-Dependent Airway and Interstitial Lung Pathology in Mice1
J Immunol (2008) 181 (5): 3698–3705.
Teleost TLR22 Recognizes RNA Duplex to Induce IFN and Protect Cells from Birnaviruses1
Aya Matsuo; Hiroyuki Oshiumi; Tadayuki Tsujita; Hiroshi Mitani; Hisae Kasai; Mamoru Yoshimizu; Misako Matsumoto; Tsukasa Seya
J Immunol (2008) 181 (5): 3474–3485.
B Cell Depletion with Anti-CD79 mAbs Ameliorates Autoimmune Disease in MRL/lpr Mice1
Yongmei Li; Fangqi Chen; Mary Putt; Yumee K. Koo; Michael Madaio; John C. Cambier; Philip L. Cohen; Robert A. Eisenberg
J Immunol (2008) 181 (5): 2961–2972.
Expression of a Soluble TGF-β Receptor by Tumor Cells Enhances Dendritic Cell/Tumor Fusion Vaccine Efficacy1
J Immunol (2008) 181 (5): 3690–3697.
CD43 Plays Both Antiadhesive and Proadhesive Roles in Neutrophil Rolling in a Context-Dependent Manner1
J Immunol (2008) 181 (5): 3628–3635.
Colocalization of Antigen-Specific B and T Cells within Ectopic Lymphoid Tissue following Immunization with Exogenous Antigen1
Jason S. Weinstein; Dina C. Nacionales; Pui Y. Lee; Kindra M. Kelly-Scumpia; Xiao-Jie Yan; Philip O. Scumpia; Dustin S. Vale-Cruz; Eric Sobel; Minoru Satoh; Nicholas Chiorazzi; Westley H. Reeves
J Immunol (2008) 181 (5): 3259–3267.
Myelin-Reactive Type B T Cells and T Cells Specific for Low-Affinity MHC-Binding Myelin Peptides Escape Tolerance in HLA-DR Transgenic Mice1
J Immunol (2008) 181 (5): 3202–3211.
Protection of Murine Systemic Lupus by the Ea Transgene without Expression of I-E Heterodimers1
J Immunol (2008) 181 (5): 3651–3657.
Induction of CD83+CD14+ Nondendritic Antigen-Presenting Cells by Exposure of Monocytes to IFN-α1
Gianni Gerlini; Giulia Mariotti; Alberto Chiarugi; Paola Di Gennaro; Roberto Caporale; Astrid Parenti; Leonardo Cavone; Adrian Tun-Kyi; Francesca Prignano; Riccardo Saccardi; Lorenzo Borgognoni; Nicola Pimpinelli
J Immunol (2008) 181 (5): 2999–3008.
TLR Adaptor MyD88 Is Essential for Pathogen Control during Oral Toxoplasma gondii Infection but Not Adaptive Immunity Induced by a Vaccine Strain of the Parasite1
Woraporn Sukhumavasi; Charlotte E. Egan; Amy L. Warren; Gregory A. Taylor; Barbara A. Fox; David J. Bzik; Eric Y. Denkers
J Immunol (2008) 181 (5): 3464–3473.
Comparative Functional Evolution of Human and Mouse CR1 and CR212
J Immunol (2008) 181 (5): 2953–2959.
Characterization of HLA Class II/Peptide-TCR Interactions of the Immunodominant T Cell Epitope in Art v 1, the Major Mugwort Pollen Allergen1
Beatrice Jahn-Schmid; Philémon Sirven; Victoria Leb; Winfried F. Pickl; Gottfried F. Fischer; Gabriele Gadermaier; Matthias Egger; Christof Ebner; Fatima Ferreira; Bernard Maillére; Barbara Bohle
J Immunol (2008) 181 (5): 3636–3642.
Lipopolysaccharide Is a Direct Agonist for Platelet RNA Splicing1
J Immunol (2008) 181 (5): 3495–3502.
Molecular Requirements for MHC Class II α-Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C1
Katherine J. Kasper; Wang Xi; A. K. M. Nur-ur Rahman; Mohammed M. Nooh; Malak Kotb; Eric J. Sundberg; Joaquín Madrenas; John K. McCormick
J Immunol (2008) 181 (5): 3384–3392.
Contribution of Mutation, Recombination, and Gene Conversion to Chicken Mhc-B Haplotype Diversity12
Kazuyoshi Hosomichi; Marcia M. Miller; Ronald M. Goto; Yujun Wang; Shingo Suzuki; Jerzy K. Kulski; Masahide Nishibori; Hidetoshi Inoko; Kei Hanzawa; Takashi Shiina
J Immunol (2008) 181 (5): 3393–3399.
The Src Kinase Lck Facilitates Assembly of HIV-1 at the Plasma Membrane1
J Immunol (2008) 181 (5): 3706–3713.
Tumor-Induced CD11b+Gr-1+ Myeloid Cells Suppress T Cell Sensitization in Tumor-Draining Lymph Nodes1
Satoshi Watanabe; Katsuya Deguchi; Rongxiu Zheng; Hidemasa Tamai; Li-xin Wang; Peter A. Cohen; Suyu Shu
J Immunol (2008) 181 (5): 3291–3300.
The Induction of Inflammation by Dectin-1 In Vivo Is Dependent on Myeloid Cell Programming and the Progression of Phagocytosis1
Marcela Rosas; Kate Liddiard; Matti Kimberg; Inês Faro-Trindade; Jacqueline U. McDonald; David L. Williams; Gordon D. Brown; Philip R. Taylor
J Immunol (2008) 181 (5): 3549–3557.
OX40/OX40L Costimulation Affects Induction of Foxp3+ Regulatory T Cells in Part by Expanding Memory T Cells In Vivo1
J Immunol (2008) 181 (5): 3193–3201.
The Major Bactericidal Activity of Human Seminal Plasma Is Zinc-Dependent and Derived from Fragmentation of the Semenogelins1
Anneli M. L. Edström; Johan Malm; Birgitta Frohm; Julie A. Martellini; Aleksander Giwercman; Matthias Mörgelin; Alexander M. Cole; Ole E. Sørensen
J Immunol (2008) 181 (5): 3413–3421.
FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase1
Stéphanie Fabre; Florent Carrette; Jing Chen; Valérie Lang; Monique Semichon; Christine Denoyelle; Vladimir Lazar; Nicolas Cagnard; Anne Dubart-Kupperschmitt; Marianne Mangeney; David A. Fruman; Georges Bismuth
J Immunol (2008) 181 (5): 2980–2989.
Critical and Differential Roles of NKp46- and NKp30-Activating Receptors Expressed by Uterine NK Cells in Early Pregnancy1
Hicham El Costa; Audrey Casemayou; Maryse Aguerre-Girr; Magali Rabot; Alain Berrebi; Olivier Parant; Muriel Clouet-Delannoy; Letizia Lombardelli; Nabila Jabrane-Ferrat; Daniel Rukavina; Armand Bensussan; Marie-Pierre Piccinni; Philippe Le Bouteiller; Julie Tabiasco
J Immunol (2008) 181 (5): 3009–3017.
Myeloid-Related Proteins Rapidly Modulate Macrophage Nitric Oxide Production during Innate Immune Response1
J Immunol (2008) 181 (5): 3595–3601.
In Vivo Suppression of Naive CD4 T Cell Responses by IL-2- and Antigen-Stimulated T Lymphocytes in the Absence of APC Competition1
J Immunol (2008) 181 (5): 3323–3335.
Synoviocyte Innate Immune Responses: I. Differential Regulation of Interferon Responses and the JNK Pathway by MAPK Kinases1
J Immunol (2008) 181 (5): 3252–3258.
Production of C5a by ASP, a Serine Protease Released from Aeromonas sobria1
Hidetoshi Nitta; Takahisa Imamura; Yoshihiro Wada; Atsushi Irie; Hidetomo Kobayashi; Keinosuke Okamoto; Hideo Baba
J Immunol (2008) 181 (5): 3602–3608.
B and T Lymphocyte Attenuator Regulates T Cell Survival in the Lung1
J Immunol (2008) 181 (5): 2973–2979.
Potent Simian Immunodeficiency Virus-Specific Cellular Immune Responses in the Breast Milk of Simian Immunodeficiency Virus-Infected, Lactating Rhesus Monkeys1
Sallie R. Permar; Helen H. Kang; Angela Carville; Keith G. Mansfield; Rebecca S. Gelman; Srinivas S. Rao; James B. Whitney; Norman L. Letvin
J Immunol (2008) 181 (5): 3643–3650.
Transcription Factor-Dependent Chromatin Remodeling of Il18r1 during Th1 and Th2 Differentiation1
J Immunol (2008) 181 (5): 3346–3352.
Gp130 Signaling Promotes Development of Acute Experimental Colitis by Facilitating Early Neutrophil/Macrophage Recruitment and Activation1
Leif E. Sander; Florian Obermeier; Uta Dierssen; Daniela C. Kroy; Anurag K. Singh; Ursula Seidler; Konrad L. Streetz; Holger H. Lutz; Werner Müller; Frank Tacke; Christian Trautwein
J Immunol (2008) 181 (5): 3586–3594.
B Lymphocyte Activation by Coinfection Prevents Immune Control of Friend Virus Infection1
J Immunol (2008) 181 (5): 3432–3440.
Nucleotide Oligomerization Domains 1 and 2: Regulation of Expression and Function in Preadipocytes1
Thorsten Stroh; Arvind Batra; Rainer Glauben; Inka Fedke; Ulrike Erben; Anjo Kroesen; Markus M. Heimesaat; Stefan Bereswill; Stephen Girardin; Martin Zeitz; Britta Siegmund
J Immunol (2008) 181 (5): 3620–3627.
PP2A Dephosphorylates Elf-1 and Determines the Expression of CD3ζ and FcRγ in Human Systemic Lupus Erythematosus T Cells1
Yuang-Taung Juang; Ying Wang; Guisen Jiang; Hai-Bin Peng; Sukran Ergin; Michelle Finnell; Abigail Magilavy; Vasileios C. Kyttaris; George C. Tsokos
J Immunol (2008) 181 (5): 3658–3664.
Tumor-Educated Tolerogenic Dendritic Cells Induce CD3ε Down-Regulation and Apoptosis of T Cells through Oxygen-Dependent Pathways1
J Immunol (2008) 181 (5): 3089–3098.
A Unique Role for the λ5 Nonimmunoglobulin Tail in Early B Lymphocyte Development1
Christian Vettermann; Kai Herrmann; Christine Albert; Edith Roth; Michael R. Bösl; Hans-Martin Jäck
J Immunol (2008) 181 (5): 3232–3242.
Immunodominance of CD4 T Cells to Foreign Antigens Is Peptide Intrinsic and Independent of Molecular Context: Implications for Vaccine Design1
Jason M. Weaver; Christopher A. Lazarski; Katherine A. Richards; Francisco A. Chaves; Scott A. Jenks; Paula R. Menges; Andrea J. Sant
J Immunol (2008) 181 (5): 3039–3048.
Apoptotic Cell-Mediated Immunoregulation of Dendritic Cells Does Not Require iC3b Opsonization1
J Immunol (2008) 181 (5): 3018–3026.
MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma1
Teresa L. Tinder; Durai B. Subramani; Gargi D. Basu; Judy M. Bradley; Jorge Schettini; Arefayene Million; Todd Skaar; Pinku Mukherjee
J Immunol (2008) 181 (5): 3116–3125.
A Critical Role for the Proapoptotic Protein Bid in Ultraviolet-Induced Immune Suppression and Cutaneous Apoptosis1
Sanjay Pradhan; Hee Kyung Kim; Christopher J. Thrash; Maureen A. Cox; Sudheer K. Mantena; Jian-He Wu; Mohammad Athar; Santosh K. Katiyar; Craig A. Elmets; Laura Timares
J Immunol (2008) 181 (5): 3077–3088.
TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol1
J Immunol (2008) 181 (5): 3049–3056.
Synthetic Peptide Dendrimers Block the Development and Expression of Experimental Allergic Encephalomyelitis1
J Immunol (2008) 181 (5): 3301–3309.
Modulation of Lipid and Protein Mediators of Inflammation by Cytosolic Phospholipase A2α during Experimental Sepsis1
J Immunol (2008) 181 (5): 3558–3566.
Combined Triggering of Dendritic Cell Receptors Results in Synergistic Activation and Potent Cytotoxic Immunity1
J Immunol (2008) 181 (5): 3422–3431.
Mononuclear Phagocyte-Derived IL-10 Suppresses the Innate IL-12/IFN-γ Axis in Lung-Challenged Aged Mice1
J Immunol (2008) 181 (5): 3156–3166.
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Cover Image
Cover Image
On the cover: Immunofluorescent staining of the serine protease tissue-type plasminogen activator (in green) in an experimentally induced acute encephalomyelitis lesion in the rat brain. The picture shows two capillaries surrounded by perivascular infiltrates of inflammatory cells. The brain endothelial cell basement membrane is shown in red, and cell nuclei are shown in blue. Reijerkerk, A., G. Kooij, S. M. A. van der Pol, T. Leyen, B. van het Hof, P.-O. Couraud, D. Vivien, C. D. Dijkstra, and H. E. de Vries. 2008. Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. J. Immunol. 181: 3567–3574.
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