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Inhibition of Arginase Activity Enhances Inflammation in Mice with Allergic Airway Disease, in Association with Increases in Protein S-Nitrosylation and Tyrosine Nitration1
Karina Ckless; Anniek Lampert; Jessica Reiss; David Kasahara; Matthew E. Poynter; Charles G. Irvin; Lennart K. A. Lundblad; Ryan Norton; Albert van der Vliet; Yvonne M. W. Janssen-Heininger
J Immunol (2008) 181 (6): 4255–4264.
Francisella tularensis Live Vaccine Strain Induces Macrophage Alternative Activation as a Survival Mechanism1
J Immunol (2008) 181 (6): 4159–4167.
Contrasting Responses of Lymphoid Progenitors to Canonical and Noncanonical Wnt Signals1
Sachin Malhotra; Yoshihiro Baba; Karla P. Garrett; Frank J. T. Staal; Rachel Gerstein; Paul W. Kincade
J Immunol (2008) 181 (6): 3955–3964.
Liver X Receptor Agonists Increase Airway Reactivity in a Model of Asthma via Increasing Airway Smooth Muscle Growth1
Mark A. Birrell; Jorge De Alba; Matthew C. Catley; Elizabeth Hardaker; Sissie Wong; Michael Collins; Deborah L. Clarke; Stuart N. Farrow; Timothy M. Willson; Jon L. Collins; Maria G. Belvisi
J Immunol (2008) 181 (6): 4265–4271.
Cytokine-Mediated Inhibition of Fibrillar Amyloid-β Peptide Degradation by Human Mononuclear Phagocytes1
J Immunol (2008) 181 (6): 3877–3886.
SAP Enables T Cells to Help B Cells by a Mechanism Distinct from Th Cell Programming or CD40 Ligand Regulation1
J Immunol (2008) 181 (6): 3994–4003.
The Production of IL-10 by Human Regulatory T Cells Is Enhanced by IL-2 through a STAT5-Responsive Intronic Enhancer in the IL-10 Locus
Kazue Tsuji-Takayama; Motoyuki Suzuki; Mayuko Yamamoto; Akira Harashima; Ayumi Okochi; Takeshi Otani; Toshiya Inoue; Akira Sugimoto; Terumasa Toraya; Makoto Takeuchi; Fumiyuki Yamasaki; Shuji Nakamura; Masayoshi Kibata
J Immunol (2008) 181 (6): 3897–3905.
Lung Resident Mesenchymal Stem Cells Isolated from Human Lung Allografts Inhibit T Cell Proliferation via a Soluble Mediator1
Lamis Jarvinen; Linda Badri; Scott Wettlaufer; Takashi Ohtsuka; Theodore J. Standiford; Galen B. Toews; David J. Pinsky; Marc Peters-Golden; Vibha N. Lama
J Immunol (2008) 181 (6): 4389–4396.
Potent Tumor-Specific Protection Ignited by Adoptively Transferred CD4+ T Cells1
J Immunol (2008) 181 (6): 4363–4370.
Fibroblast-Type Reticular Stromal Cells Regulate the Lymph Node Vasculature1
Susan Chyou; Eric H. Ekland; April C. Carpenter; Te-Chen Jenny Tzeng; Sha Tian; Michael Michaud; Joseph A. Madri; Theresa T. Lu
J Immunol (2008) 181 (6): 3887–3896.
Lipids Including Cholesteryl Linoleate and Cholesteryl Arachidonate Contribute to the Inherent Antibacterial Activity of Human Nasal Fluid1
Thai Q. Do; Safiehkhatoon Moshkani; Patricia Castillo; Suda Anunta; Adelina Pogosyan; Annie Cheung; Beth Marbois; Kym F. Faull; William Ernst; Su Ming Chiang; Gary Fujii; Catherine F. Clarke; Krishna Foster; Edith Porter
J Immunol (2008) 181 (6): 4177–4187.
Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors1
J Immunol (2008) 181 (6): 4043–4051.
PIR-B-Deficient Mice Are Susceptible to Salmonella Infection1
Ikuko Torii; Satoshi Oka; Muneki Hotomi; William H. Benjamin, Jr; Toshiyuki Takai; John F. Kearney; David E. Briles; Hiromi Kubagawa
J Immunol (2008) 181 (6): 4229–4239.
Cathelicidin Antimicrobial Peptides Inhibit Hyaluronan-Induced Cytokine Release and Modulate Chronic Allergic Dermatitis1
J Immunol (2008) 181 (6): 3915–3922.
Sulfhydryl-Based Tumor Antigen-Carrier Protein Conjugates Stimulate Superior Antitumor Immunity against B Cell Lymphomas1
J Immunol (2008) 181 (6): 4131–4140.
IL-12Rβ2 Promotes the Development of CD4+CD25+ Regulatory T Cells1
Zhao Zhao; Shuo Yu; Denise C. Fitzgerald; Mohamed Elbehi; Bogoljub Ciric; A. M. Rostami; Guang-Xian Zhang
J Immunol (2008) 181 (6): 3870–3876.
Rab27a Regulates Exocytosis of Tertiary and Specific Granules in Human Neutrophils1
J Immunol (2008) 181 (6): 3793–3803.
RAGE Ligation Affects T Cell Activation and Controls T Cell Differentiation1
Yali Chen; Eitan M. Akirav; Wei Chen; Octavian Henegariu; Bernhard Moser; Dharmesh Desai; Jane M. Shen; Jeffery C. Webster; Robert C. Andrews; Adnan M. Mjalli; Robert Rothlein; Ann Marie Schmidt; Raphael Clynes; Kevan C. Herold
J Immunol (2008) 181 (6): 4272–4278.
A Human Dendritic Cell Subset Receptive to the Venezuelan Equine Encephalitis Virus-Derived Replicon Particle Constitutively Expresses IL-321
J Immunol (2008) 181 (6): 4010–4018.
Fibroblastic Reticular Cells Guide T Lymphocyte Entry into and Migration within the Splenic T Cell Zone1
J Immunol (2008) 181 (6): 3947–3954.
Elevated Numbers of FcγRIIIA+ (CD16+) Effector CD8 T Cells with NK Cell-Like Function in Chronic Hepatitis C Virus Infection1
Niklas K. Björkström; Veronica D. Gonzalez; Karl-Johan Malmberg; Karolin Falconer; Annette Alaeus; Greg Nowak; Carl Jorns; Bo-Göran Ericzon; Ola Weiland; Johan K. Sandberg; Hans-Gustaf Ljunggren
J Immunol (2008) 181 (6): 4219–4228.
Characterization of a Novel Nonclassical T Cell Clone with Broad Reactivity against Human Renal Cell Carcinomas1
J Immunol (2008) 181 (6): 3769–3776.
Response to Comment on “Characterizing the N-Terminal Processing Motif of MHC Class I Ligands”
J Immunol (2008) 181 (6): 3731–3732.
A RAG1 Mutation Found in Omenn Syndrome Causes Coding Flank Hypersensitivity: A Novel Mechanism for Antigen Receptor Repertoire Restriction1
J Immunol (2008) 181 (6): 4124–4130.
Resistin Inhibits Essential Functions of Polymorphonuclear Leukocytes
J Immunol (2008) 181 (6): 3761–3768.
TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice1
Laura McKinley; John F. Alcorn; Alanna Peterson; Rachel B. DuPont; Shernaaz Kapadia; Alison Logar; Adam Henry; Charles G. Irvin; Jon D. Piganelli; Anuradha Ray; Jay K. Kolls
J Immunol (2008) 181 (6): 4089–4097.
Inside-Out Regulation of FcαRI (CD89) Depends on PP2A1
Jantine E. Bakema; Annie Bakker; Simone de Haij; Henk Honing; Madelon Bracke; Leo Koenderman; Gestur Vidarsson; Jan G. J. van de Winkel; Jeanette H. W. Leusen
J Immunol (2008) 181 (6): 4080–4088.
B Cell Receptor Affinity and B Cell Subset Identity Integrate to Define the Effectiveness, Affinity Threshold, and Mechanism of Anergy1
J Immunol (2008) 181 (6): 3834–3840.
TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation1
J Immunol (2008) 181 (6): 4279–4286.
Plasmacytoid Dendritic Cells Take Up Opsonized Antigen Leading to CD4+ and CD8+ T Cell Activation In Vivo1
J Immunol (2008) 181 (6): 3811–3817.
TLR2 Expression in Astrocytes Is Induced by TNF-α- and NF-κB-Dependent Pathways1
J Immunol (2008) 181 (6): 3841–3849.
Hydrogen Sulfide Augments Neutrophil Migration through Enhancement of Adhesion Molecule Expression and Prevention of CXCR2 Internalization: Role of ATP-Sensitive Potassium Channels1
Daniela Dal-Secco; Thiago M. Cunha; Andressa Freitas; José Carlos Alves-Filho; Fabrício O. Souto; Sandra Y. Fukada; Renata Grespan; Nylane M. N. Alencar; Alberto F. Neto; Marcos A. Rossi; Sérgio H. Ferreira; John S. Hothersall; Fernando Q. Cunha
J Immunol (2008) 181 (6): 4287–4298.
Evidence for an Association between Thyroid-Stimulating Hormone and Insulin-Like Growth Factor 1 Receptors: A Tale of Two Antigens Implicated in Graves’ Disease1
Shanli Tsui; Vibha Naik; Neil Hoa; Catherine J. Hwang; Nikoo F. Afifiyan; Amiya Sinha Hikim; Andrew G. Gianoukakis; Raymond S. Douglas; Terry J. Smith
J Immunol (2008) 181 (6): 4397–4405.
CD137 Induces Proliferation of Murine Hematopoietic Progenitor Cells and Differentiation to Macrophages1
J Immunol (2008) 181 (6): 3923–3932.
Endogenous Hydrogen Sulfide Regulates Inflammatory Response by Activating the ERK Pathway in Polymicrobial Sepsis1
J Immunol (2008) 181 (6): 4320–4331.
An Atypical NF-κB-Regulated Pathway Mediates Phorbol Ester-Dependent Heme Oxygenase-1 Gene Activation in Monocytes1
J Immunol (2008) 181 (6): 4113–4123.
Characterization of T Cell Responses to the RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis in BALB/c Mice1
J Immunol (2008) 181 (6): 4150–4158.
CD8+ Th17 Mediate Costimulation Blockade-Resistant Allograft Rejection in T-bet-Deficient Mice1
J Immunol (2008) 181 (6): 3906–3914.
CD8+ T Cells Targeting a Single Immunodominant Epitope are Sufficient for Elimination of Established SV40 T Antigen-Induced Brain Tumors1
Angela M. Tatum; Lawrence M. Mylin; Susan J. Bender; Matthew A. Fischer; Beth A. Vigliotti; M. Judith Tevethia; Satvir S. Tevethia; Todd D. Schell
J Immunol (2008) 181 (6): 4406–4417.
High Mobility Group Protein-1 Inhibits Phagocytosis of Apoptotic Neutrophils through Binding to Phosphatidylserine1
J Immunol (2008) 181 (6): 4240–4246.
Cross-Tolerization between Nod1 and Nod2 Signaling Results in Reduced Refractoriness to Bacterial Infection in Nod2-Deficient Macrophages1
J Immunol (2008) 181 (6): 4340–4346.
TGF-β Utilizes SMAD3 to Inhibit CD16-Mediated IFN-γ Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells1
Rossana Trotta; Jessica Dal Col; Jianhua Yu; David Ciarlariello; Brittany Thomas; Xiaoli Zhang; Jeffrey Allard, II; Min Wei; Hsiaoyin Mao; John C. Byrd; Danilo Perrotti; Michael A. Caligiuri
J Immunol (2008) 181 (6): 3784–3792.
Effector Mechanisms of the Autoimmune Syndrome in the Murine Model of Autoimmune Polyglandular Syndrome Type 11
Jason J. DeVoss; Anthony K. Shum; Kellsey P. A. Johannes; Wen Lu; Anna K. Krawisz; Peter Wang; Ting Yang; Norbert P. LeClair; Cecilia Austin; Erich C. Strauss; Mark S. Anderson
J Immunol (2008) 181 (6): 4072–4079.
B7-H3 Contributes to the Development of Pathogenic Th2 Cells in a Murine Model of Asthma1
Osamu Nagashima; Norihiro Harada; Yoshihiko Usui; Tomohide Yamazaki; Hideo Yagita; Ko Okumura; Kazuhisa Takahashi; Hisaya Akiba
J Immunol (2008) 181 (6): 4062–4071.
Unique Properties of the Chicken TLR4/MD-2 Complex: Selective Lipopolysaccharide Activation of the MyD88-Dependent Pathway1
J Immunol (2008) 181 (6): 4354–4362.
Cholera Toxin B Accelerates Disease Progression in Lupus-Prone Mice by Promoting Lipid Raft Aggregation1
J Immunol (2008) 181 (6): 4019–4026.
Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome
Mirjam Kool; Virginie Pétrilli; Thibaut De Smedt; Aline Rolaz; Hamida Hammad; Menno van Nimwegen; Ingrid M. Bergen; Rosa Castillo; Bart N. Lambrecht; Jürg Tschopp
J Immunol (2008) 181 (6): 3755–3759.
Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis1
Richard A. O'Connor; Catriona T. Prendergast; Catherine A. Sabatos; Clement W. Z. Lau; Melanie D. Leech; David C. Wraith; Stephen M. Anderton
J Immunol (2008) 181 (6): 3750–3754.
Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells1
Federica Casiraghi; Nadia Azzollini; Paola Cassis; Barbara Imberti; Marina Morigi; Daniela Cugini; Regiane Aparecida Cavinato; Marta Todeschini; Samantha Solini; Aurelio Sonzogni; Norberto Perico; Giuseppe Remuzzi; Marina Noris
J Immunol (2008) 181 (6): 3933–3946.
Importance of TLR2 in Early Innate Immune Response to Acute Pulmonary Infection with Porphyromonas gingivalis in Mice1
J Immunol (2008) 181 (6): 4141–4149.
Defects in Skin γδ T Cell Function Contribute to Delayed Wound Repair in Rapamycin-Treated Mice1
J Immunol (2008) 181 (6): 3974–3983.
MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection1
Adeeb H. Rahman; Weiguo Cui; David F. LaRosa; Devon K. Taylor; Jidong Zhang; Daniel R. Goldstein; E. John Wherry; Susan M. Kaech; Laurence A. Turka
J Immunol (2008) 181 (6): 3804–3810.
Intradermal Administration of Thymic Stromal Lymphopoietin Induces a T Cell- and Eosinophil-Dependent Systemic Th2 Inflammatory Response
Heidi K. Jessup; Avery W. Brewer; Miyuki Omori; Erika A. Rickel; Alison L. Budelsky; Bo-Rin Park Yoon; Steven F. Ziegler; Michael R. Comeau
J Immunol (2008) 181 (6): 4311–4319.
Acid Sphingomyelinase Amplifies Redox Signaling in Pseudomonas aeruginosa-Induced Macrophage Apoptosis1
J Immunol (2008) 181 (6): 4247–4254.
Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities
Erika A. Rickel; Lori A. Siegel; Bo-Rin Park Yoon; James B. Rottman; David G. Kugler; David A. Swart; Penny M. Anders; Joel E. Tocker; Michael R. Comeau; Alison L. Budelsky
J Immunol (2008) 181 (6): 4299–4310.
A Novel Role for Non-Neutralizing Antibodies against Nucleoprotein in Facilitating Resistance to Influenza Virus1
J Immunol (2008) 181 (6): 4168–4176.
Elevating Calcium in Th2 Cells Activates Multiple Pathways to Induce IL-4 Transcription and mRNA Stabilization1
J Immunol (2008) 181 (6): 3984–3993.
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Cover Image
Cover Image
On the cover: A critical role for T cells in Aire-deficient mice. Spontaneous autoimmunity in Aire-deficient mice targets a number of different organs, including the retina. Aire-deficient mice that lack T cells are completely free of disease. In contrast, Aire-deficient mice devoid of B cells still develop autoimmunity including inflammatory infiltrates in the retina (shown). DeVoss, J. J., A. K. Shum, K. P. A. Johannes, W. Lu, A. K. Krawisz, P. Wang, T. Yang, N. P. LeClair, C. Austin, E. C. Strauss, and M. S. Anderson. 2008. Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1. J. Immunol. 181: 4072–4079.
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