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J Immunol (2008) 181 (9): 5811–5812.

View articletitled, IN THIS ISSUE

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LETTERS TO THE EDITOR

Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections”

Jiezhong Chen

J Immunol (2008) 181 (9): 5813.

View articletitled, Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections”

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Response to Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections”

David K. Meyerholz; Michelle Edsen-Moore; Jodi McGill; Ruth A. Coleman; Robert T. Cook; Kevin L. Legge

J Immunol (2008) 181 (9): 5813–5814.

View articletitled, Response to Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections”

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PILLARS OF IMMUNOLOGY

The “Bubble Boy” Paradox: An Answer That Led to a Question

Leslie J. Berg

J Immunol (2008) 181 (9): 5815–5816.

View articletitled, The “Bubble Boy” Paradox: An Answer That Led to a Question

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Pillars Article: Interleukin-2 Receptor γ Chain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. Cell 73: 147–157.

Masayuki Noguchi; Huafang Yi; Howard M. Rosenblatt; Alexandra H. Filipovich; Stephen Adelstein; William S. Modi; O. Wesley McBride; Warren J. Leonard

J Immunol (2008) 181 (9): 5817–5827.

View articletitled, Pillars Article: Interleukin-2 Receptor γ Chain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. <em>Cell</em> 73: 147–157.

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BRIEF REVIEWS

Macrophages as APC and the Dendritic Cell Myth

David A. Hume

J Immunol (2008) 181 (9): 5829–5835.

View articletitled, Macrophages as APC and the Dendritic Cell Myth

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CUTTING EDGE

Cutting Edge: Local Recall Responses by Memory T Cells Newly Recruited to Peripheral Nonlymphoid Tissues

Linda M. Wakim; Thomas Gebhardt; William R. Heath; Francis R. Carbone

J Immunol (2008) 181 (9): 5837–5841.

View articletitled, Cutting Edge: Local Recall Responses by Memory T Cells Newly Recruited to Peripheral Nonlymphoid Tissues

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Cutting Edge: IFN-γ Enables APC to Promote Memory Th17 and Abate Th1 Cell Development ¹

Ilona Kryczek; Shuang Wei; Wenrong Gong; Xiaogong Shu; Wojciech Szeliga; Linhua Vatan; Lieping Chen; Guobin Wang; Weiping Zou

J Immunol (2008) 181 (9): 5842–5846.

View articletitled, Cutting Edge: IFN-γ Enables APC to Promote Memory Th17 and Abate Th1 Cell Development<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Jakmip1 Is Expressed upon T Cell Differentiation and Has an Inhibitory Function in Cytotoxic T Lymphocytes ¹

Valentina Libri; Dörte Schulte; Amber van Stijn; Josiane Ragimbeau; Lars Rogge; Sandra Pellegrini

J Immunol (2008) 181 (9): 5847–5856.

View articletitled, Jakmip1 Is Expressed upon T Cell Differentiation and Has an Inhibitory Function in Cytotoxic T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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NF-κB Modulates Sensitivity to Apoptosis, Proinflammatory and Migratory Potential in Short- versus Long-Term Cultured Human γδ Lymphocytes

Marina Ferrarini; Fanny Delfanti; Monica Gianolini; Chiara Rizzi; Massimo Alfano; Adriano Lazzarin; Priscilla Biswas

J Immunol (2008) 181 (9): 5857–5864.

View articletitled, NF-κB Modulates Sensitivity to Apoptosis, Proinflammatory and Migratory Potential in Short- versus Long-Term Cultured Human γδ Lymphocytes

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A Complex Interplay among Virus, Dendritic Cells, T Cells, and Cytokines in Dengue Virus Infections ¹

Wanwisa Dejnirattisai; Thaneeya Duangchinda; Chen-Lung Steve Lin; Sirijitt Vasanawathana; Meleri Jones; Michael Jacobs; Prida Malasit; Xiao-ning Xu; Gavin Screaton; Juthathip Mongkolsapaya

J Immunol (2008) 181 (9): 5865–5874.

View articletitled, A Complex Interplay among Virus, Dendritic Cells, T Cells, and Cytokines in Dengue Virus Infections<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-α ¹

Melissa B. Uccellini; Liliana Busconi; Nathaniel M. Green; Patricia Busto; Sean R. Christensen; Mark J. Shlomchik; Ann Marshak-Rothstein; Gregory A. Viglianti

J Immunol (2008) 181 (9): 5875–5884.

View articletitled, Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-α<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors ¹

Qi Yang; Lela Kardava; Anthony St. Leger; Kathleen Martincic; Barbara Varnum-Finney; Irwin D. Bernstein; Christine Milcarek; Lisa Borghesi

J Immunol (2008) 181 (9): 5885–5894.

View articletitled, E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Pathogenic Effector T Cell Enrichment Overcomes Regulatory T Cell Control and Generates Autoimmune Gastritis ¹

João P. Monteiro; Julia Farache; Ana Carolina Mercadante; Julio A. Mignaco; Martin Bonamino; Adriana Bonomo

J Immunol (2008) 181 (9): 5895–5903.

View articletitled, Pathogenic Effector T Cell Enrichment Overcomes Regulatory T Cell Control and Generates Autoimmune Gastritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Quantitative Trait Locus on Chromosome 4 Affects Cycling of Hematopoietic Stem and Progenitor Cells through Regulation of TGF-β2 Responsiveness ¹

Serine Avagyan; Ludmila Glouchkova; Juhyun Choi; Hans-Willem Snoeck

J Immunol (2008) 181 (9): 5904–5911.

View articletitled, A Quantitative Trait Locus on Chromosome 4 Affects Cycling of Hematopoietic Stem and Progenitor Cells through Regulation of TGF-β2 Responsiveness<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Fas Expression on Antigen-Specific T Cells Has Costimulatory, Helper, and Down-Regulatory Functions In Vivo for Cytotoxic T Cell Responses but Not for T Cell-Dependent B Cell Responses ¹

Irina Puliaeva; Roman Puliaev; Andrei Shustov; Mark Haas; Charles S. Via

J Immunol (2008) 181 (9): 5912–5929.

View articletitled, Fas Expression on Antigen-Specific T Cells Has Costimulatory, Helper, and Down-Regulatory Functions In Vivo for Cytotoxic T Cell Responses but Not for T Cell-Dependent B Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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SIT and TRIM Determine T Cell Fate in the Thymus ¹

Uwe Koelsch; Burkhart Schraven; Luca Simeoni

J Immunol (2008) 181 (9): 5930–5939.

View articletitled, SIT and TRIM Determine T Cell Fate in the Thymus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification of CD25⁺ γδ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers ¹

Kensuke Shibata; Hisakata Yamada; Risa Nakamura; Xun Sun; Momoe Itsumi; Yasunobu Yoshikai

J Immunol (2008) 181 (9): 5940–5947.

View articletitled, Identification of CD25<sup>+</sup> γδ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage ¹

Gretta L. Stritesky; Norman Yeh; Mark H. Kaplan

J Immunol (2008) 181 (9): 5948–5955.

View articletitled, IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells ¹

Akira Maeda; Agatha Schwarz; Ann Bullinger; Akimichi Morita; David Peritt; Thomas Schwarz

J Immunol (2008) 181 (9): 5956–5962.

View articletitled, Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Rho-ROCK-Dependent Ezrin-Radixin-Moesin Phosphorylation Regulates Fas-Mediated Apoptosis in Jurkat Cells ¹

Marylise Hébert; Sophie Potin; Michaël Sebbagh; Jacques Bertoglio; Jacqueline Bréard; Jocelyne Hamelin

J Immunol (2008) 181 (9): 5963–5973.

View articletitled, Rho-ROCK-Dependent Ezrin-Radixin-Moesin Phosphorylation Regulates Fas-Mediated Apoptosis in Jurkat Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Heterospecific CD4 Help to Rescue CD8 T Cell Killers ¹

Marie-Ghislaine de Goër de Herve; Anne Cariou; Federico Simonetta; Yassine Taoufik

J Immunol (2008) 181 (9): 5974–5980.

View articletitled, Heterospecific CD4 Help to Rescue CD8 T Cell Killers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor ¹

Maho Suzukawa; Motoyasu Iikura; Rikiya Koketsu; Hiroyuki Nagase; Chise Tamura; Akiko Komiya; Susumu Nakae; Kouji Matsushima; Ken Ohta; Kazuhiko Yamamoto; Masao Yamaguchi

J Immunol (2008) 181 (9): 5981–5989.

View articletitled, An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8⁺ T Cells ¹

Seyed Fazlollah Mousavi; Pejman Soroosh; Takeshi Takahashi; Yasunobu Yoshikai; Hao Shen; Leo Lefrançois; Jannie Borst; Kazuo Sugamura; Naoto Ishii

J Immunol (2008) 181 (9): 5990–6001.

View articletitled, OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TCR Complex-Activated CD8 Adhesion Function by Human T Cells ¹

Jay C. Varghese; Kevin P. Kane

J Immunol (2008) 181 (9): 6002–6009.

View articletitled, TCR Complex-Activated CD8 Adhesion Function by Human T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A KIR Haplotype ¹

Cyril Fauriat; Sandra Andersson; Andreas T. Björklund; Mattias Carlsten; Marie Schaffer; Niklas K. Björkström; Bettina C. Baumann; Jakob Michaëlsson; Hans-Gustaf Ljunggren; Karl-Johan Malmberg

J Immunol (2008) 181 (9): 6010–6019.

View articletitled, Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A <em>KIR</em> Haplotype<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity ¹

Wanhong Ding; Lori L. Stohl; John A. Wagner; Richard D. Granstein

J Immunol (2008) 181 (9): 6020–6026.

View articletitled, Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Intraclonal Competition Inhibits the Formation of High-Affinity Antibody-Secreting Cells ¹

Thuc-vy L. Le; Tea Hyun Kim; David D. Chaplin

J Immunol (2008) 181 (9): 6027–6037.

View articletitled, Intraclonal Competition Inhibits the Formation of High-Affinity Antibody-Secreting Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4⁺CD25⁻LAP⁺ Regulatory T Cell and Is Associated with Down-Regulation of IL-17⁺CD4⁺ICOS⁺CXCR5⁺ Follicular Helper T Cells ¹

Henry Yim Wu; Francisco J. Quintana; Howard L. Weiner

J Immunol (2008) 181 (9): 6038–6050.

View articletitled, Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4<sup>+</sup>CD25<sup>−</sup>LAP<sup>+</sup> Regulatory T Cell and Is Associated with Down-Regulation of IL-17<sup>+</sup>CD4<sup>+</sup>ICOS<sup>+</sup>CXCR5<sup>+</sup> Follicular Helper T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-24 Induces Apoptosis of Chronic Lymphocytic Leukemia B Cells Engaged into the Cell Cycle through Dephosphorylation of STAT3 and Stabilization of p53 Expression

Alexander Sainz-Perez; Hélène Gary-Gouy; Françoise Gaudin; Ghyath Maarof; Anne Marfaing-Koka; Thierry de Revel; Ali Dalloul

J Immunol (2008) 181 (9): 6051–6060.

View articletitled, IL-24 Induces Apoptosis of Chronic Lymphocytic Leukemia B Cells Engaged into the Cell Cycle through Dephosphorylation of STAT3 and Stabilization of p53 Expression

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Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis ¹

Takafumi Yokota; Kenji Oritani; Karla P. Garrett; Taku Kouro; Makoto Nishida; Isao Takahashi; Michiko Ichii; Yusuke Satoh; Paul W. Kincade; Yuzuru Kanakura

J Immunol (2008) 181 (9): 6061–6072.

View articletitled, Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H3 ¹

Yasuhiro Nagai; Hisashi Aso; Hideki Ogasawara; Sachi Tanaka; Yoshikazu Taketa; Kouichi Watanabe; Shyuichi Ohwada; Michael T. Rose; Haruki Kitazawa; Takahiro Yamaguchi

J Immunol (2008) 181 (9): 6073–6081.

View articletitled, Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development ¹

Rustom Falahati; David Leitenberg

J Immunol (2008) 181 (9): 6082–6091.

View articletitled, Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Central Tolerance Regulates B Cells Reactive with Goodpasture Antigen α3(IV)NC1 Collagen ¹

Ying Zhang; Susan C. Su; Douglas B. Hecox; Graham F. Brady; Katherine M. Mackin; Amy G. Clark; Mary H. Foster

J Immunol (2008) 181 (9): 6092–6100.

View articletitled, Central Tolerance Regulates B Cells Reactive with Goodpasture Antigen α3(IV)NC1 Collagen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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An Epithelial Progenitor Pool Regulates Thymus Growth ¹

William E. Jenkinson; Andrea Bacon; Andrea J. White; Graham Anderson; Eric J. Jenkinson

J Immunol (2008) 181 (9): 6101–6108.

View articletitled, An Epithelial Progenitor Pool Regulates Thymus Growth<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Expression of CD86 on Human Islet Endothelial Cells Facilitates T Cell Adhesion and Migration ¹

Biliana Lozanoska-Ochser; Nigel J. Klein; Guo C. Huang; Raymond A. Alvarez; Mark Peakman

J Immunol (2008) 181 (9): 6109–6116.

View articletitled, Expression of CD86 on Human Islet Endothelial Cells Facilitates T Cell Adhesion and Migration<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma ¹

Chuanwang Song; Liqiong Luo; Zhang Lei; Bo Li; Zhihui Liang; Guanghui Liu; Dong Li; Guimei Zhang; Bo Huang; Zuo-Hua Feng

J Immunol (2008) 181 (9): 6117–6124.

View articletitled, IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses ¹

Nisebita Sahu; Ana M. Venegas; Dragana Jankovic; Wayne Mitzner; Julio Gomez-Rodriguez; Jennifer L. Cannons; Connie Sommers; Paul Love; Alan Sher; Pamela L. Schwartzberg; Avery August

J Immunol (2008) 181 (9): 6125–6131.

View articletitled, Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Critical Role of TLR9 in Acute Graft-versus-Host Disease ¹

Claudia Calcaterra; Lucia Sfondrini; Anna Rossini; Michele Sommariva; Cristiano Rumio; Sylvie Ménard; Andrea Balsari

J Immunol (2008) 181 (9): 6132–6139.

View articletitled, Critical Role of TLR9 in Acute Graft-versus-Host Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Unique Receptor Repertoire in Mouse Uterine NK cells ¹

Hakim Yadi; Shannon Burke; Zofia Madeja; Myriam Hemberger; Ashley Moffett; Francesco Colucci

J Immunol (2008) 181 (9): 6140–6147.

View articletitled, Unique Receptor Repertoire in Mouse Uterine NK cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunosurveillance of Lung Melanoma Metastasis in EBI-3-Deficient Mice Mediated by CD8⁺ T Cells ¹

Kerstin A. Sauer; Joachim H. Maxeiner; Roman Karwot; Petra Scholtes; Hans A. Lehr; Mark Birkenbach; Richard S. Blumberg; Susetta Finotto

J Immunol (2008) 181 (9): 6148–6157.

View articletitled, Immunosurveillance of Lung Melanoma Metastasis in EBI-3-Deficient Mice Mediated by CD8<sup>+</sup> T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cross-Linking of B7-H1 on EBV-Transformed B Cells Induces Apoptosis through Reactive Oxygen Species Production, JNK Signaling Activation, and fasL Expression ¹

Yeong Seok Kim; Ga Bin Park; Hyun-Kyung Lee; Hyunkeun Song; In-Hak Choi; Wang Jae Lee; Dae Young Hur

J Immunol (2008) 181 (9): 6158–6169.

View articletitled, Cross-Linking of B7-H1 on EBV-Transformed B Cells Induces Apoptosis through Reactive Oxygen Species Production, JNK Signaling Activation, and fasL Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Human NK Cells Kill Resting but Not Activated Microglia via NKG2D- and NKp46-Mediated Recognition ¹

Anna Lünemann; Jan D. Lünemann; Susanne Roberts; Brady Messmer; Rosa Barreira da Silva; Cedric S. Raine; Christian Münz

J Immunol (2008) 181 (9): 6170–6177.

View articletitled, Human NK Cells Kill Resting but Not Activated Microglia via NKG2D- and NKp46-Mediated Recognition<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CX₃CR1⁺c-kit⁺ Bone Marrow Cells Give Rise to CD103⁺ and CD103⁻ Dendritic Cells with Distinct Functional Properties ¹

Maria-Luisa del Rio; Jose-Ignacio Rodriguez-Barbosa; Jasmin Bölter; Matthias Ballmaier; Oliver Dittrich-Breiholz; Michael Kracht; Steffen Jung; Reinhold Förster

J Immunol (2008) 181 (9): 6178–6188.

View articletitled, CX<sub>3</sub>CR1<sup>+</sup>c-kit<sup>+</sup> Bone Marrow Cells Give Rise to CD103<sup>+</sup> and CD103<sup>−</sup> Dendritic Cells with Distinct Functional Properties<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs ¹

Tomoya Katakai; Hidenori Suto; Manabu Sugai; Hiroyuki Gonda; Atsushi Togawa; Sachiko Suematsu; Yukihiko Ebisuno; Koko Katagiri; Tatsuo Kinashi; Akira Shimizu

J Immunol (2008) 181 (9): 6189–6200.

View articletitled, Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Mycobacterium bovis Bacille Calmette-Guérin Infection in the CNS Suppresses Experimental Autoimmune Encephalomyelitis and Th17 Responses in an IFN-γ-Independent Manner ¹

JangEun Lee; Emily K. Reinke; Alla L. Zozulya; Matyas Sandor; Zsuzsanna Fabry

J Immunol (2008) 181 (9): 6201–6212.

View articletitled, <em>Mycobacterium bovis</em> Bacille Calmette-Guérin Infection in the CNS Suppresses Experimental Autoimmune Encephalomyelitis and Th17 Responses in an IFN-γ-Independent Manner<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

Sonia Schoonbroodt; Mieke Steukers; Malini Viswanathan; Nicolas Frans; Marie Timmermans; Anita Wehnert; Minh Nguyen; Robert Charles Ladner; René M. Hoet

J Immunol (2008) 181 (9): 6213–6221.

View articletitled, Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

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Transcription Factor Gfi1 Restricts B Cell-Mediated Autoimmunity ¹

Chozhavendan Rathinam; Hans Lassmann; Michael Mengel; Christoph Klein

J Immunol (2008) 181 (9): 6222–6229.

View articletitled, Transcription Factor Gfi1 Restricts B Cell-Mediated Autoimmunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes ¹

Yanay Ofran; Avner Schlessinger; Burkhard Rost

J Immunol (2008) 181 (9): 6230–6235.

View articletitled, Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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n-3 Polyunsaturated Fatty Acids Suppress the Localization and Activation of Signaling Proteins at the Immunological Synapse in Murine CD4⁺ T Cells by Affecting Lipid Raft Formation ¹

Wooki Kim; Yang-Yi Fan; Rola Barhoumi; Roger Smith; David N. McMurray; Robert S. Chapkin

J Immunol (2008) 181 (9): 6236–6243.

View articletitled, n-3 Polyunsaturated Fatty Acids Suppress the Localization and Activation of Signaling Proteins at the Immunological Synapse in Murine CD4<sup>+</sup> T Cells by Affecting Lipid Raft Formation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Loss of Protein Kinase Cθ, Bcl10, or Malt1 Selectively Impairs Proliferation and NF-κB Activation in the CD4⁺ T Cell Subset ¹

Lara M. Kingeter; Brian C. Schaefer

J Immunol (2008) 181 (9): 6244–6254.

View articletitled, Loss of Protein Kinase Cθ, Bcl10, or Malt1 Selectively Impairs Proliferation and NF-κB Activation in the CD4<sup>+</sup> T Cell Subset<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation ¹

Lindsay L. Jones; Leremy A. Colf; Jennifer D. Stone; K. Christopher Garcia; David M. Kranz

J Immunol (2008) 181 (9): 6255–6264.

View articletitled, Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Ikaros Regulates Notch Target Gene Expression in Developing Thymocytes ¹

Sheila Chari; Susan Winandy

J Immunol (2008) 181 (9): 6265–6274.

View articletitled, Ikaros Regulates Notch Target Gene Expression in Developing Thymocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Regulates Quality of Processed Peptides Presented by MHC Class I Molecules ¹

Takayuki Kanaseki; Nilabh Shastri

J Immunol (2008) 181 (9): 6275–6282.

View articletitled, Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Regulates Quality of Processed Peptides Presented by MHC Class I Molecules<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

Impact of Protective IL-2 Allelic Variants on CD4⁺Foxp3⁺ Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice ¹

Evridiki Sgouroudis; Alexandre Albanese; Ciriaco A. Piccirillo

J Immunol (2008) 181 (9): 6283–6292.

View articletitled, Impact of Protective IL-2 Allelic Variants on CD4<sup>+</sup>Foxp3<sup>+</sup> Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Polymorphic Sites Away from the Bw4 Epitope That Affect Interaction of Bw4⁺ HLA-B with KIR3DL1 ¹

Bharati Sanjanwala; Monia Draghi; Paul J. Norman; Lisbeth A. Guethlein; Peter Parham

J Immunol (2008) 181 (9): 6293–6300.

View articletitled, Polymorphic Sites Away from the Bw4 Epitope That Affect Interaction of Bw4<sup>+</sup> HLA-B with KIR3DL1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization ¹

Benjamin N. Bimber; Anna J. Moreland; Roger W. Wiseman; Austin L. Hughes; David H. O'Connor

J Immunol (2008) 181 (9): 6301–6308.

View articletitled, Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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HOST DEFENSE

An Indispensable Role for the Chemokine Receptor CCR10 in IgA Antibody-Secreting Cell Accumulation ¹

Olivier Morteau; Craig Gerard; Bao Lu; Sorina Ghiran; Miriam Rits; Yuko Fujiwara; Yuetching Law; Kathryn Distelhorst; Elizabeth M. Nielsen; Erica D. Hill; Raymond Kwan; Nicole H. Lazarus; Eugene C. Butcher; Eric Wilson

J Immunol (2008) 181 (9): 6309–6315.

View articletitled, An Indispensable Role for the Chemokine Receptor CCR10 in IgA Antibody-Secreting Cell Accumulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Novel Role of CD30L/CD30 Signaling by T-T Cell Interaction in Th1 Response against Mycobacterial Infection ¹

Ce Tang; Hisakata Yamada; Kensuke Shibata; Hiromi Muta; Worawidh Wajjwalku; Eckhard R. Podack; Yasunobu Yoshikai

J Immunol (2008) 181 (9): 6316–6327.

View articletitled, A Novel Role of CD30L/CD30 Signaling by T-T Cell Interaction in Th1 Response against Mycobacterial Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immune Evasion of Enterococcus faecalis by an Extracellular Gelatinase That Cleaves C3 and iC3b ¹

Shin Yong Park; Yong Pyo Shin; Chong Han Kim; Ho Jin Park; Yeon Sun Seong; Byung Sam Kim; Sook Jae Seo; In Hee Lee

J Immunol (2008) 181 (9): 6328–6336.

View articletitled, Immune Evasion of <em>Enterococcus faecalis</em> by an Extracellular Gelatinase That Cleaves C3 and iC3b<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV ¹

Fumihiko Yasui; Chieko Kai; Masahiro Kitabatake; Shingo Inoue; Misako Yoneda; Shoji Yokochi; Ryoichi Kase; Satoshi Sekiguchi; Kouichi Morita; Tsunekazu Hishima; Hidenori Suzuki; Katsuo Karamatsu; Yasuhiro Yasutomi; Hisatoshi Shida; Minoru Kidokoro; Kyosuke Mizuno; Kouji Matsushima; Michinori Kohara

J Immunol (2008) 181 (9): 6337–6348.

View articletitled, Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes ¹

Markus Sköld; Samuel M. Behar

J Immunol (2008) 181 (9): 6349–6360.

View articletitled, Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Design, Expression, and Processing of Epitomized Hepatitis C Virus-Encoded CTL Epitopes ¹

Daniel Yerly; David Heckerman; Todd Allen; Todd J. Suscovich; Nebojsa Jojic; Carl Kadie; Werner J. Pichler; Andreas Cerny; Christian Brander

J Immunol (2008) 181 (9): 6361–6370.

View articletitled, Design, Expression, and Processing of Epitomized Hepatitis C Virus-Encoded CTL Epitopes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Long-Term Immunity against Actual Poxviral HLA Ligands as Identified by Differential Stable Isotope Labeling ¹

Verena S. Meyer; Wolfgang Kastenmuller; Georg Gasteiger; Mirita Franz-Wachtel; Tobias Lamkemeyer; Hans-Georg Rammensee; Stefan Stevanovic; Dagmar Sigurdardottir; Ingo Drexler

J Immunol (2008) 181 (9): 6371–6383.

View articletitled, Long-Term Immunity against Actual Poxviral HLA Ligands as Identified by Differential Stable Isotope Labeling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CCL3-CCR5 Axis Regulates Intratumoral Accumulation of Leukocytes and Fibroblasts and Promotes Angiogenesis in Murine Lung Metastasis Process ¹

Yu Wu; Ying-Yi Li; Kouji Matsushima; Tomohisa Baba; Naofumi Mukaida

J Immunol (2008) 181 (9): 6384–6393.

View articletitled, CCL3-CCR5 Axis Regulates Intratumoral Accumulation of Leukocytes and Fibroblasts and Promotes Angiogenesis in Murine Lung Metastasis Process<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Ly49h-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex ¹

Nassima Fodil-Cornu; Seung-Hwan Lee; Simon Belanger; Andrew P. Makrigiannis; Christine A. Biron; R. Mark Buller; Silvia M. Vidal

J Immunol (2008) 181 (9): 6394–6405.

View articletitled, <em>Ly49h</em>-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells ¹

Tzong-Shi Lu; Hava Karsenty Avraham; Seyha Seng; Souvenir D. Tachado; Henry Koziel; Alexandros Makriyannis; Shalom Avraham

J Immunol (2008) 181 (9): 6406–6416.

View articletitled, Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis ¹

Cristina P. Marques; Maxim C-J. Cheeran; Joseph M. Palmquist; Shuxian Hu; Stina L. Urban; James R. Lokensgard

J Immunol (2008) 181 (9): 6417–6426.

View articletitled, Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF-κB Activation via the DNA-Dependent Activator of IFN Regulatory Factors ¹

William J. Kaiser; Jason W. Upton; Edward S. Mocarski

J Immunol (2008) 181 (9): 6427–6434.

View articletitled, Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF-κB Activation via the DNA-Dependent Activator of IFN Regulatory Factors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T Cell Repertoire ¹

Matthias Wölfl; Alleluiah Rutebemberwa; Timothy Mosbruger; Qing Mao; Hong-mei Li; Dale Netski; Stuart C. Ray; Drew Pardoll; John Sidney; Alessandro Sette; Todd Allen; Thomas Kuntzen; Daniel G. Kavanagh; Jürgen Kuball; Philip D. Greenberg; Andrea L. Cox

J Immunol (2008) 181 (9): 6435–6446.

View articletitled, Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T Cell Repertoire<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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MyD88 Signaling Is Not Essential for Induction of Antigen-Specific B Cell Responses but Is Indispensable for Protection against Streptococcus pneumoniae Infection following Oral Vaccination with Attenuated Salmonella Expressing PspA Antigen ¹

Sung-Moo Park; Hyun-Jeong Ko; Doo-Hee Shim; Jin-Young Yang; Yong-Ho Park; Roy Curtiss, III; Mi-Na Kweon

J Immunol (2008) 181 (9): 6447–6455.

View articletitled, MyD88 Signaling Is Not Essential for Induction of Antigen-Specific B Cell Responses but Is Indispensable for Protection against <em>Streptococcus pneumoniae</em> Infection following Oral Vaccination with Attenuated <em>Salmonella</em> Expressing PspA Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Expansion of Foxp3⁺ Regulatory T Cells in Mice Infected with the Filarial Parasite Brugia malayi¹

Henry J. McSorley; Yvonne M. Harcus; Janice Murray; Matthew D. Taylor; Rick M. Maizels

J Immunol (2008) 181 (9): 6456–6466.

View articletitled, Expansion of Foxp3<sup>+</sup> Regulatory T Cells in Mice Infected with the Filarial Parasite <em>Brugia malayi</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Level of Hepatitis B Virus Replication Is Not Affected by Protein ISG15 Modification but Is Reduced by Inhibition of UBP43 (USP18) Expression ¹

Jung-Hwan Kim; Jiann-Kae Luo; Dong-Er Zhang

J Immunol (2008) 181 (9): 6467–6472.

View articletitled, The Level of Hepatitis B Virus Replication Is Not Affected by Protein ISG15 Modification but Is Reduced by Inhibition of UBP43 (USP18) Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

Functional Dichotomy of Dendritic Cells following Interaction with Leishmania braziliensis: Infected Cells Produce High Levels of TNF-α, whereas Bystander Dendritic Cells Are Activated to Promote T Cell Responses ¹

Lucas P. Carvalho; Edward J. Pearce; Phillip Scott

J Immunol (2008) 181 (9): 6473–6480.

View articletitled, Functional Dichotomy of Dendritic Cells following Interaction with <em>Leishmania braziliensis</em>: Infected Cells Produce High Levels of TNF-α, whereas Bystander Dendritic Cells Are Activated to Promote T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury ¹

Alicia A. Babcock; Henrik Toft-Hansen; Trevor Owens

J Immunol (2008) 181 (9): 6481–6490.

View articletitled, Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes ¹

Hajo Haase; Julia L. Ober-Blöbaum; Gabriela Engelhardt; Silke Hebel; Antje Heit; Holger Heine; Lothar Rink

J Immunol (2008) 181 (9): 6491–6502.

View articletitled, Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-4-Induced Selective Clearance of Oligomeric β-Amyloid Peptide_1–42 by Rat Primary Type 2 Microglia ¹

Eisuke Shimizu; Kohichi Kawahara; Makoto Kajizono; Makoto Sawada; Hitoshi Nakayama

J Immunol (2008) 181 (9): 6503–6513.

View articletitled, IL-4-Induced Selective Clearance of Oligomeric β-Amyloid Peptide<sub>1–42</sub> by Rat Primary Type 2 Microglia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo ¹

Vincent Dioszeghy; Marcela Rosas; Benjamin H. Maskrey; Chantal Colmont; Nicholas Topley; Pavlos Chaitidis; Hartmut Kühn; Simon A. Jones; Philip R. Taylor; Valerie B. O'Donnell

J Immunol (2008) 181 (9): 6514–6524.

View articletitled, 12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses ¹

AnnaMaria De Filippo; Robert J. Binder; Chiara Camisaschi; Valeria Beretta; Flavio Arienti; Antonello Villa; Pamela Della Mina; Giorgio Parmiani; Licia Rivoltini; Chiara Castelli

J Immunol (2008) 181 (9): 6525–6535.

View articletitled, Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells ¹

Jimmy W. Lee; Ping Wang; Michael G. Kattah; Sawsan Youssef; Lawrence Steinman; Kathryn DeFea; Daniel S. Straus

J Immunol (2008) 181 (9): 6536–6545.

View articletitled, Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CCR5 Deficiency Aggravates Crescentic Glomerulonephritis in Mice ¹

Jan-Eric Turner; Hans-Joachim Paust; Oliver M. Steinmetz; Anett Peters; Catherine Meyer-Schwesinger; Felix Heymann; Udo Helmchen; Susanne Fehr; Richard Horuk; Ulrich Wenzel; Christian Kurts; Hans-Willi Mittrücker; Rolf A. K. Stahl; Ulf Panzer

J Immunol (2008) 181 (9): 6546–6556.

View articletitled, CCR5 Deficiency Aggravates Crescentic Glomerulonephritis in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Reversal of Thymic Stromal Lymphopoietin-Induced Airway Inflammation through Inhibition of Th2 Responses ¹

Baohua Zhou; Mark B. Headley; Theingi Aye; Joel Tocker; Michael R. Comeau; Steven F. Ziegler

J Immunol (2008) 181 (9): 6557–6562.

View articletitled, Reversal of Thymic Stromal Lymphopoietin-Induced Airway Inflammation through Inhibition of Th2 Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils ¹

Nicola Tamassia; Vincent Le Moigne; Marzia Rossato; Marta Donini; Stephen McCartney; Federica Calzetti; Marco Colonna; Flavia Bazzoni; Marco A. Cassatella

J Immunol (2008) 181 (9): 6563–6573.

View articletitled, Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Analysis of CD97 Expression and Manipulation: Antibody Treatment but Not Gene Targeting Curtails Granulocyte Migration ¹

Henrike Veninga; Susann Becker; Robert M. Hoek; Manja Wobus; Elke Wandel; Jos van der Kaa; Martin van der Valk; Alex F. de Vos; Hannelore Haase; Bronwyn Owens; Tom van der Poll; René A. W. van Lier; J. Sjef Verbeek; Gabriela Aust; Jörg Hamann

J Immunol (2008) 181 (9): 6574–6583.

View articletitled, Analysis of CD97 Expression and Manipulation: Antibody Treatment but Not Gene Targeting Curtails Granulocyte Migration<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis ¹

Yu-Huei Liu; Chang-Yueh Lin; Wei-Chou Lin; Sai-Wen Tang; Ming-Kuen Lai; Jung-Yaw Lin

J Immunol (2008) 181 (9): 6584–6594.

View articletitled, Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Carcinoembryonic Antigen-Specific but Not Antiviral CD4⁺ T Cell Immunity Is Impaired in Pancreatic Carcinoma Patients ¹

Elena Tassi; Francesca Gavazzi; Luca Albarello; Vladimir Senyukov; Renato Longhi; Paolo Dellabona; Claudio Doglioni; Marco Braga; Valerio Di Carlo; Maria Pia Protti

J Immunol (2008) 181 (9): 6595–6603.

View articletitled, Carcinoembryonic Antigen-Specific but Not Antiviral CD4<sup>+</sup> T Cell Immunity Is Impaired in Pancreatic Carcinoma Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects ¹

Min Kim; Janette Taylor; John Sidney; Zorka Mikloska; Neil Bodsworth; Katerina Lagios; Heather Dunckley; Karen Byth-Wilson; Martine Denis; Robert Finlayson; Rajiv Khanna; Alessandro Sette; Anthony L. Cunningham

J Immunol (2008) 181 (9): 6604–6615.

View articletitled, Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Strategic Nonmyeloablative Conditioning: CD154:CD40 Costimulatory Blockade at Primary Bone Marrow Transplantation Promotes Engraftment for Secondary Bone Marrow Transplantation after Engraftment Failure ¹

Hong Xu; Yiming Huang; Paula M. Chilton; Lala-Rukh Hussain; Michael K. Tanner; Jun Yan; Suzanne T. Ildstad

J Immunol (2008) 181 (9): 6616–6624.

View articletitled, Strategic Nonmyeloablative Conditioning: CD154:CD40 Costimulatory Blockade at Primary Bone Marrow Transplantation Promotes Engraftment for Secondary Bone Marrow Transplantation after Engraftment Failure<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Characterization of the Antibody Response against NeuGcGM3 Ganglioside Elicited in Non-Small Cell Lung Cancer Patients Immunized with an Anti-Idiotype Antibody ¹

Ana María Hernández; Darién Toledo; Darel Martínez; Tania Griñán; Victor Brito; Amparo Macías; Sailyn Alfonso; Teresa Rondón; Eduardo Suárez; Ana María Vázquez; Rolando Pérez

J Immunol (2008) 181 (9): 6625–6634.

View articletitled, Characterization of the Antibody Response against NeuGcGM3 Ganglioside Elicited in Non-Small Cell Lung Cancer Patients Immunized with an Anti-Idiotype Antibody<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Activation of Antigen-Specific Cytotoxic T Lymphocytes by β₂-Microglobulin or TAP1 Gene Disruption and the Introduction of Recipient-Matched MHC Class I Gene in Allogeneic Embryonic Stem Cell-Derived Dendritic Cells ¹

Yusuke Matsunaga; Daiki Fukuma; Shinya Hirata; Satoshi Fukushima; Miwa Haruta; Tokunori Ikeda; Izumi Negishi; Yasuharu Nishimura; Satoru Senju

J Immunol (2008) 181 (9): 6635–6643.

View articletitled, Activation of Antigen-Specific Cytotoxic T Lymphocytes by β<sub>2</sub>-Microglobulin or TAP1 Gene Disruption and the Introduction of Recipient-Matched MHC Class I Gene in Allogeneic Embryonic Stem Cell-Derived Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunization with a Mimotope of GD2 Ganglioside Induces CD8⁺ T Cells That Recognize Cell Adhesion Molecules on Tumor Cells ¹

Andrzej Wierzbicki; Margaret Gil; Michael Ciesielski; Robert A. Fenstermaker; Yutaro Kaneko; Hanna Rokita; Joseph T. Lau; Danuta Kozbor

J Immunol (2008) 181 (9): 6644–6653.

View articletitled, Immunization with a Mimotope of GD2 Ganglioside Induces CD8<sup>+</sup> T Cells That Recognize Cell Adhesion Molecules on Tumor Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Bone Marrow-Derived IFN-Producing Killer Dendritic Cells Account for the Tumoricidal Activity of Unpulsed Dendritic Cells ¹

Nourredine Himoudi; Stephen Nabarro; Jo Buddle; Ayad Eddaoudi; Adrian J. Thrasher; John Anderson

J Immunol (2008) 181 (9): 6654–6663.

View articletitled, Bone Marrow-Derived IFN-Producing Killer Dendritic Cells Account for the Tumoricidal Activity of Unpulsed Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions ¹

Lucie Baudino; Yasuro Shinohara; Falk Nimmerjahn; Jun-Ichi Furukawa; Munehiro Nakata; Eduardo Martínez-Soria; Franz Petry; Jeffery V. Ravetch; Shin-Ichiro Nishimura; Shozo Izui

J Immunol (2008) 181 (9): 6664–6669.

View articletitled, Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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LETTERS OF RETRACTION

Retraction: Dual Effect of AMD3100, a CXCR4 Antagonist, on Bleomycin-Indiced Lung Inflammation

Masaki Watanabe; Yuko Shirahama; Hideo Mitsuyama; Ken-ichi Oonakahara; Satoshi Noma; Ikkou Higashimoto; Mitsuhiro Osame; Kimiyoshi Arimura

J Immunol (2008) 181 (9): 6670.

View articletitled, Retraction: Dual Effect of AMD3100, a CXCR4 Antagonist, on Bleomycin-Indiced Lung Inflammation

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Retraction: Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation

Masaki Watanabe; Yuko Shirahama; Ryuki Hirano; Hideo Mitsuyama; Ikkou Higashimoto; Mitsuhiro Osame; Kimiyoshi Arimura

J Immunol (2008) 181 (9): 6671.

View articletitled, Retraction: Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation

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Retraction: Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Fibrosis

Masaki Watanabe; Yuko Shirahama; Ken-ichi Oonakahara; Ikkou Higashimoto; Mitsuhiro Osame; Kimiyoshi Arimura; Teizo Yoshimura

J Immunol (2008) 181 (9): 6672.

View articletitled, Retraction: Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Fibrosis

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Cover Image

Cover Image

On the cover: Expansion of MAdCAM-1⁺ marginal reticular cell (MRC) layer at the outermost region immediately underneath the subcapsular sinus of postnatally growing mesenteric lymph node (MLN). Immunofluorescent staining of MAdCAM-1 (orange) and laminin (green) in day 6 mouse MLN. MAdCAM-1 is also highly expressed by blood vessels (inner ring-like structures). Katakai, T., H. Suto, M. Sugai, H. Gonda, A. Togawa, S. Suematsu, Y. Ebisuno, K. Katagiri, T. Kinashi, and A. Shimizu. 2008. Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J. Immunol. 181: 6189–6200.
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