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Issues
1 June 2009
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
Pillars Article: Sequence and Specificity of Two Antibacterial Proteins Involved in Insect Immunity. Nature 1981. 292: 246–248
J Immunol (2009) 182 (11): 6635–6637.
CUTTING EDGE
Cutting Edge: Highly Alloreactive Dual TCR T Cells Play a Dominant Role in Graft-versus-Host Disease1
J Immunol (2009) 182 (11): 6639–6643.
Cutting Edge: CD28 Engagement Releases Antigen-Activated Invariant NKT Cells from the Inhibitory Effects of PD-11
J Immunol (2009) 182 (11): 6644–6647.
Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 11
J Immunol (2009) 182 (11): 6648–6652.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells1
Joseph F. Grosso; Monica V. Goldberg; Derese Getnet; Tullia C. Bruno; Hung-Rong Yen; Kristin J. Pyle; Edward Hipkiss; Dario A. A. Vignali; Drew M. Pardoll; Charles G. Drake
J Immunol (2009) 182 (11): 6659–6669.
Interaction of the Hepatitis B Core Antigen and the Innate Immune System1
Byung O. Lee; Amy Tucker; Lars Frelin; Matti Sallberg; Joyce Jones; Cory Peters; Janice Hughes; David Whitacre; Bryan Darsow; Darrell L. Peterson; David R. Milich
J Immunol (2009) 182 (11): 6670–6681.
PD-1-Mediated Suppression of IL-2 Production Induces CD8+ T Cell Anergy In Vivo1
Shunsuke Chikuma; Seigo Terawaki; Tamon Hayashi; Ryusuke Nabeshima; Takao Yoshida; Shiro Shibayama; Taku Okazaki; Tasuku Honjo
J Immunol (2009) 182 (11): 6682–6689.
Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae1
J Immunol (2009) 182 (11): 6690–6696.
Chronic Antigen Stimulation Alone Is Sufficient to Drive CD8+ T Cell Exhaustion1
J Immunol (2009) 182 (11): 6697–6708.
Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice1
J Immunol (2009) 182 (11): 6709–6717.
Phenotypic and Functional Analyses of KIR3DL1+ and KIR3DS1+ NK Cell Subsets Demonstrate Differential Regulation by Bw4 Molecules and Induced KIR3DS1 Expression on Stimulated NK Cells1
Maelig Morvan; Catherine Willem; Katia Gagne; Nolwenn Kerdudou; Gaelle David; Véronique Sébille; Gilles Folléa; Jean-Denis Bignon; Christelle Retière
J Immunol (2009) 182 (11): 6727–6735.
CARMA1 Controls an Early Checkpoint in the Thymic Development of FoxP3+ Regulatory T Cells1
Luciana L. Molinero; Jianying Yang; Thomas Gajewski; Clara Abraham; Michael A. Farrar; Maria-Luisa Alegre
J Immunol (2009) 182 (11): 6736–6743.
Hypercostimulation through 4-1BB Distorts Homeostasis of Immune Cells1
J Immunol (2009) 182 (11): 6753–6762.
IL-15 Renders Conventional Lymphocytes Resistant to Suppressive Functions of Regulatory T Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway1
Mélika Ben Ahmed; Nadia Belhadj Hmida; Nicolette Moes; Sophie Buyse; Maha Abdeladhim; Hechmi Louzir; Nadine Cerf-Bensussan
J Immunol (2009) 182 (11): 6763–6770.
Tumoricidal Effects of Activated Macrophages in a Mouse Model of Chronic Lymphocytic Leukemia1
J Immunol (2009) 182 (11): 6771–6778.
Teleost B7 Expressed on Monocytes Regulates T Cell Responses12
J Immunol (2009) 182 (11): 6799–6806.
Impaired NFAT Transcriptional Activity in Antigen-Stimulated CD8 T Cells Linked to Defective Phosphorylation of NFAT Transactivation Domain1
Stéphane Leung-Theung-Long; Isabelle Mondor; Martine Guiraud; Camille Lamare; Viswas Nageleekar; Pierre-Emmanuel Paulet; Mercedes Rincon; Sylvie Guerder
J Immunol (2009) 182 (11): 6807–6814.
CD2 Distinguishes Two Subsets of Human Plasmacytoid Dendritic Cells with Distinct Phenotype and Functions1
Toshimichi Matsui; John E. Connolly; Mark Michnevitz; Damien Chaussabel; Chun-I Yu; Casey Glaser; Sasha Tindle; Marc Pypaert; Heidi Freitas; Bernard Piqueras; Jacques Banchereau; A. Karolina Palucka
J Immunol (2009) 182 (11): 6815–6823.
Selection of Molecular Structure and Delivery of RNA Oligonucleotides to Activate TLR7 versus TLR8 and to Induce High Amounts of IL-12p70 in Primary Human Monocytes1
Andrea Ablasser; Hendrik Poeck; David Anz; Michael Berger; Martin Schlee; Sarah Kim; Carole Bourquin; Nadege Goutagny; Zhaozhao Jiang; Katherine A. Fitzgerald; Simon Rothenfusser; Stefan Endres; Gunther Hartmann; Veit Hornung
J Immunol (2009) 182 (11): 6824–6833.
CD40-Independent Engagement of Mammalian hsp70 by Antigen-Presenting Cells1
J Immunol (2009) 182 (11): 6844–6850.
Chemokine Receptor CCR7 Contributes to a Rapid and Efficient Clearance of Lytic Murine γ-Herpes Virus 68 from the Lung, Whereas Bronchus-Associated Lymphoid Tissue Harbors Virus during Latency1
Jessica R. Kocks; Heiko Adler; Heike Danzer; Katharina Hoffmann; Danny Jonigk; Ulrich Lehmann; Reinhold Förster
J Immunol (2009) 182 (11): 6861–6869.
Vav1 Is Essential for Mechanotactic Crawling and Migration of Neutrophils out of the Inflamed Microvasculature1
Mia Phillipson; Bryan Heit; Sean A. Parsons; Björn Petri; Sarah C. Mullaly; Pina Colarusso; R. Michael Gower; Gregory Neely; Scott I. Simon; Paul Kubes
J Immunol (2009) 182 (11): 6870–6878.
Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones1
Frank Timmermans; Imke Velghe; Lieve Vanwalleghem; Magda De Smedt; Stefanie Van Coppernolle; Tom Taghon; Harry D. Moore; Georges Leclercq; Anton W. Langerak; Tessa Kerre; Jean Plum; Bart Vandekerckhove
J Immunol (2009) 182 (11): 6879–6888.
The Golgi-Associated Protein p115 Mediates the Secretion of Macrophage Migration Inhibitory Factor1
Melanie Merk; John Baugh; Swen Zierow; Lin Leng; Utpal Pal; Seung Joon Lee; Antje D. Ebert; Yuka Mizue; John O. Trent; Robert Mitchell; Walter Nickel; Paula B. Kavathas; Jürgen Bernhagen; Richard Bucala
J Immunol (2009) 182 (11): 6896–6906.
Macrophage Migration Inhibitory Factor Homologs of Anisakis simplex Suppress Th2 Response in Allergic Airway Inflammation Model via CD4+CD25+Foxp3+ T Cell Recruitment1
Sang Kyun Park; Min Kyoung Cho; Hye-Kyung Park; Keun Hee Lee; Sun Joo Lee; Seon Hee Choi; Mee Sun Ock; Hae Jin Jeong; Moo Hyung Lee; Hak Sun Yu
J Immunol (2009) 182 (11): 6907–6914.
In Situ IL-12/23p40 Production during Mycobacterial Infection Is Sustained by CD11bhigh Dendritic Cells Localized in Tissue Sites Distinct from Those Harboring Bacilli1
Antonio Gigliotti Rothfuchs; Jackson G. Egen; Carl G. Feng; Lis R. V. Antonelli; Andre Bafica; Nathalie Winter; Richard M. Locksley; Alan Sher
J Immunol (2009) 182 (11): 6915–6925.
IL-7 Promotes CXCR3 Ligand-Dependent T Cell Antitumor Reactivity in Lung Cancer1
Åsa Andersson; Seok-Chul Yang; Min Huang; Li Zhu; Upendra K. Kar; Raj K. Batra; David Elashoff; Robert M. Strieter; Steven M. Dubinett; Sherven Sharma
J Immunol (2009) 182 (11): 6951–6958.
Dendritic Cells Use Endocytic Pathway for Cross-Priming Class Ib MHC-Restricted CD8αα+TCRαβ+ T Cells with Regulatory Properties1
J Immunol (2009) 182 (11): 6959–6968.
Myosin IIA Associates with NK Cell Lytic Granules to Enable Their Interaction with F-Actin and Function at the Immunological Synapse1
Keri B. Sanborn; Gregory D. Rak; Saumya Y. Maru; Korey Demers; Analisa Difeo; John A. Martignetti; Michael R. Betts; Rémi Favier; Pinaki P. Banerjee; Jordan S. Orange
J Immunol (2009) 182 (11): 6969–6984.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
The Chicken Leukocyte Receptor Complex Encodes a Family of Different Affinity FcY Receptors12
J Immunol (2009) 182 (11): 6985–6992.
CD45-Mediated Fodrin Cleavage during Galectin-1 T Cell Death Promotes Phagocytic Clearance of Dying Cells1
J Immunol (2009) 182 (11): 7001–7008.
The Binding of Factor H to a Complex of Physiological Polyanions and C3b on Cells Is Impaired in Atypical Hemolytic Uremic Syndrome1
Viviana P. Ferreira; Andrew P. Herbert; Claudio Cortés; Kristi A. McKee; Bärbel S. Blaum; Stefan T. Esswein; Dušan Uhrín; Paul N. Barlow; Michael K. Pangburn; David Kavanagh
J Immunol (2009) 182 (11): 7009–7018.
Cloning, Expression, and Mapping of Allergenic Determinants of αS1-Casein, a Major Cow’s Milk Allergen1
Ulrike Schulmeister; Heidrun Hochwallner; Ines Swoboda; Margarete Focke-Tejkl; Beate Geller; Mats Nystrand; Annika Härlin; Josef Thalhamer; Sandra Scheiblhofer; Walter Keller; Bodo Niggemann; Santiago Quirce; Christoph Ebner; Adriano Mari; Gabrielle Pauli; Udo Herz; Rudolf Valenta; Susanne Spitzauer
J Immunol (2009) 182 (11): 7019–7029.
Fatty Acyl Structures of Mycobacterium tuberculosis Sulfoglycolipid Govern T Cell Response1
Julie Guiard; Anthony Collmann; Luis Fernando Garcia-Alles; Lionel Mourey; Thérèse Brando; Lucia Mori; Martine Gilleron; Jacques Prandi; Gennaro De Libero; Germain Puzo
J Immunol (2009) 182 (11): 7030–7037.
De Novo Ceramide Synthesis Is Required for N-Linked Glycosylation in Plasma Cells1
Meidan Goldfinger; Elad L. Laviad; Rivka Hadar; Miri Shmuel; Arie Dagan; Hyejung Park; Alfred H. Merrill, Jr; Israel Ringel; Anthony H. Futerman; Boaz Tirosh
J Immunol (2009) 182 (11): 7038–7047.
Inhibition and Genetic Deficiency of p38 MAPK Up-Regulates Heme Oxygenase-1 Gene Expression via Nrf21
J Immunol (2009) 182 (11): 7048–7057.
HOST DEFENSE
Antiviral Antibodies Target Adenovirus to Phagolysosomes and Amplify the Innate Immune Response1
Anne K. Zaiss; Akosua Vilaysane; Matthew J. Cotter; Sharon A. Clark; H. Christopher Meijndert; Pina Colarusso; Robin M. Yates; Virginie Petrilli; Jurg Tschopp; Daniel A. Muruve
J Immunol (2009) 182 (11): 7058–7068.
Identification of an IFN-γ-Producing Neutrophil Early in the Response to Listeria monocytogenes1
J Immunol (2009) 182 (11): 7069–7073.
The UDP-Glucose Receptor P2RY14 Triggers Innate Mucosal Immunity in the Female Reproductive Tract by Inducing IL-81
Toru Arase; Hiroshi Uchida; Takashi Kajitani; Masanori Ono; Kayoko Tamaki; Hideyuki Oda; Sayaka Nishikawa; Maki Kagami; Takashi Nagashima; Hirotaka Masuda; Hironori Asada; Yasunori Yoshimura; Tetsuo Maruyama
J Immunol (2009) 182 (11): 7074–7084.
Airway Delivery of Silica Increases Susceptibility to Mycobacterial Infection in Mice: Potential Role of Repopulating Macrophages1
J Immunol (2009) 182 (11): 7102–7109.
TLR2 Deficiency Leads to Increased Th17 Infiltrates in Experimental Brain Abscesses1
J Immunol (2009) 182 (11): 7119–7130.
Kinetics of Expansion of Epitope-Specific T Cell Responses during Primary HIV-1 Infection1
Emma L. Turnbull; MaiLee Wong; Shuyi Wang; Xiping Wei; Nicola A. Jones; Karen E. Conrod; Diana Aldam; Jo Turner; Pierre Pellegrino; Brandon F. Keele; Ian Williams; George M. Shaw; Persephone Borrow
J Immunol (2009) 182 (11): 7131–7145.
Miltefosine Promotes IFN-γ-Dominated Anti-Leishmanial Immune Response1
J Immunol (2009) 182 (11): 7146–7154.
MHC Class I Dk Locus and Ly49G2+ NK Cells Confer H-2k Resistance to Murine Cytomegalovirus1
J Immunol (2009) 182 (11): 7163–7171.
Antigen Load Governs the Differential Priming of CD8 T Cells in Response to the Bacille Calmette Guérin Vaccine or Mycobacterium tuberculosis Infection1
Anthony A. Ryan; Jonathan K. Nambiar; Teresa M. Wozniak; Ben Roediger; Elena Shklovskaya; Warwick J. Britton; Barbara Fazekas de St. Groth; James A. Triccas
J Immunol (2009) 182 (11): 7172–7177.
Multiple Mechanisms Contribute to Impairment of Type 1 Interferon Production during Chronic Lymphocytic Choriomeningitis Virus Infection of Mice1
J Immunol (2009) 182 (11): 7178–7189.
INFLAMMATION
Myeloid-Specific Deletion of Tumor Suppressor PTEN Augments Neutrophil Transendothelial Migration during Inflammation1
Bara Sarraj; Steffen Massberg; Yitang Li; Anongnard Kasorn; Kulandayan Subramanian; Fabien Loison; Leslie E. Silberstein; Ulrich von Andrian; Hongbo R. Luo
J Immunol (2009) 182 (11): 7190–7200.
Suppression of NF-κB by Cyclosporin A and Tacrolimus (FK506) via Induction of the C/EBP Family: Implication for Unfolded Protein Response1
Shuqi Du; Nobuhiko Hiramatsu; Kunihiro Hayakawa; Ayumi Kasai; Maro Okamura; Tao Huang; Jian Yao; Masayuki Takeda; Isao Araki; Norifumi Sawada; Adrienne W. Paton; James C. Paton; Masanori Kitamura
J Immunol (2009) 182 (11): 7201–7211.
MFG-E8 Attenuates Intestinal Inflammation in Murine Experimental Colitis by Modulating Osteopontin-Dependent αvβ3 Integrin Signaling1
Md. Monowar Aziz; Shunji Ishihara; Yoshiyuki Mishima; Naoki Oshima; Ichiro Moriyama; Takafumi Yuki; Yasunori Kadowaki; Mohammad Azharul Karim Rumi; Yuji Amano; Yoshikazu Kinoshita
J Immunol (2009) 182 (11): 7222–7232.
Coronin-1 Is Associated with Neutrophil Survival and Is Cleaved during Apoptosis: Potential Implication in Neutrophils from Cystic Fibrosis Patients1
Sandra Moriceau; Chahrazade Kantari; Julie Mocek; Noélie Davezac; Julie Gabillet; Ida Chiara Guerrera; Frank Brouillard; Danielle Tondelier; Isabelle Sermet-Gaudelus; Claire Danel; Gérard Lenoir; Soizic Daniel; Aleksander Edelman; Véronique Witko-Sarsat
J Immunol (2009) 182 (11): 7254–7263.
Recombinant Soluble Human FcγR1A (CD64A) Reduces Inflammation in Murine Collagen-Induced Arthritis1
Jeff L. Ellsworth; Nels Hamacher; Brandon Harder; Ken Bannink; Thomas R. Bukowski; Kelly Byrnes-Blake; Sara Underwood; Colleen Oliver; Kimberly S. Waggie; Claire Noriega; LuAnne Hebb; Mark W. Rixon; Katherine E. Lewis
J Immunol (2009) 182 (11): 7272–7279.
Lipopolysaccharide-Induced Apoptosis in Transformed Bovine Brain Endothelial Cells and Human Dermal Microvessel Endothelial Cells: The Role of JNK1
J Immunol (2009) 182 (11): 7280–7286.
CLINICAL IMMUNOLOGY
Efficient Killing of Human Colon Cancer Stem Cells by γδ T Lymphocytes1
Matilde Todaro; Matilde D'Asaro; Nadia Caccamo; Flora Iovino; Maria Giovanna Francipane; Serena Meraviglia; Valentina Orlando; Carmela La Mendola; Gaspare Gulotta; Alfredo Salerno; Francesco Dieli; Giorgio Stassi
J Immunol (2009) 182 (11): 7287–7296.
CD27 Expression on CD4+ T Cells Differentiates Effector from Regulatory T Cell Subsets in the Lung1
J Immunol (2009) 182 (11): 7317–7324.
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Cover Image
Cover Image
On the cover: Human embryonic stem cells colonies generate hematopoietic zones upon transfer on OP9 feeder layers. These hematopoietic zones are endothelium-lined structures containing round CD34+CD43+ hematopoietic precursor cells. Transfer of such zones on Delta-ligand 1-expressing OP9 cells results in differentiation to mature T cells. Timmermans, F., I. Velghe, L. Vanwalleghem, M. De Smedt, S. Van Coppernolle, T. Taghon, H. D. Moore, G. Leclercq, A. W. Langerak, T. Kerre, J. Plum, and B. Vandekerckhove. 2009. Generation of T cells from human embryonic stem cell-derived hematopoietic zones. J. Immunol. 182: 6879–6888.
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