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Issues
15 April 2009
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
Comment on “Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching”
Hideharu Sekine; Ricardo C. Ferreira; Qiang Pan-Hammarström; Lennart Hammarström; Gary S. Gilkeson; Timothy W. Behrens
J Immunol (2009) 182 (8): 4495–4496.
BRIEF REVIEWS
Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer 1
J Immunol (2009) 182 (8): 4499–4506.
CUTTING EDGE
Cutting Edge: IL-2 Immune Complexes As a Therapy for Persistent Virus Infection 1
J Immunol (2009) 182 (8): 4512–4515.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
IL-22-Dependent Attenuation of T Cell-Dependent (ConA) Hepatitis in Herpes Virus Entry Mediator Deficiency 1
J Immunol (2009) 182 (8): 4521–4528.
Early Hematopoietic Zinc Finger Protein Prevents Tumor Cell Recognition by Natural Killer Cells1
Rosanna La Rocca; Mariateresa Fulciniti; Tadepally Lakshmikanth; Maria Mesuraca; Talib Hassan Ali; Valerio Mazzei; Nicola Amodio; Lucio Catalano; Bruno Rotoli; Ouathek Ouerfelli; Michele Grieco; Elio Gulletta; Heather M. Bond; Giovanni Morrone; Soldano Ferrone; Ennio Carbone
J Immunol (2009) 182 (8): 4529–4537.
Induction of Tumor Cell Apoptosis or Necrosis by Conditional Expression of Cell Death Proteins: Analysis of Cell Death Pathways and In Vitro Immune Stimulatory Potential 1
Christine Lohmann; Andreas Muschaweckh; Susanne Kirschnek; Luise Jennen; Hermann Wagner; Georg Häcker
J Immunol (2009) 182 (8): 4538–4546.
FcγRIIA and FcγRIIIB Mediate Nuclear Factor Activation through Separate Signaling Pathways in Human Neutrophils 1
J Immunol (2009) 182 (8): 4547–4556.
Costimulation of Dendritic Epidermal γδ T Cells by a New NKG2D Ligand Expressed Specifically in the Skin 1
J Immunol (2009) 182 (8): 4557–4564.
A Single-Chain H-2Db Molecule Presenting an Influenza Virus Nucleoprotein Epitope Shows Enhanced Ability at Stimulating CD8+ T Cell Responses In Vivo 1
Michael J. Palmowski; Mathew Parker; Kaushik Choudhuri; Christopher Chiu; Margaret F. C. Callan; P. Anton van der Merwe; Vincenzo Cerundolo; Keith G. Gould
J Immunol (2009) 182 (8): 4565–4571.
NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model 1
J Immunol (2009) 182 (8): 4572–4580.
Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands 1
J Immunol (2009) 182 (8): 4581–4589.
Rabbit Polyclonal Mouse Antithymocyte Globulin Administration Alters Dendritic Cell Profile and Function in NOD Mice to Suppress Diabetogenic Responses 1
Yanfei Huang; Matthew Parker; Changqing Xia; Ruihua Peng; Clive Wasserfall; Tracy Clarke; Lizhen Wu; Tayseer Chowdhry; Martha Campbell-Thompson; John Williams; Michael Clare-Salzler; Mark A. Atkinson; Karl L. Womer
J Immunol (2009) 182 (8): 4608–4615.
The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells 1
Jeffrey M. Wilson; William G. Ross; Oma N. Agbai; Renea Frazier; Robert A. Figler; Jayson Rieger; Joel Linden; Peter B. Ernst
J Immunol (2009) 182 (8): 4616–4623.
Activin A Promotes the TGF-β-Induced Conversion of CD4+CD25− T Cells into Foxp3+ Induced Regulatory T Cells 1
Samuel Huber; Felix R. Stahl; Jörg Schrader; Stefan Lüth; Katrin Presser; Antonella Carambia; Richard A. Flavell; Sabine Werner; Manfred Blessing; Johannes Herkel; Christoph Schramm
J Immunol (2009) 182 (8): 4633–4640.
Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development 1
Marcin P. Mycko; Isabel Ferrero; Anne Wilson; Wei Jiang; Teresa Bianchi; Andreas Trumpp; H. Robson MacDonald
J Immunol (2009) 182 (8): 4641–4648.
Langerhans Cells Are Not Required for the CD8 T Cell Response to Epidermal Self-Antigens 1
J Immunol (2009) 182 (8): 4657–4664.
Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells 1
Derese Getnet; Charles H. Maris; Edward L. Hipkiss; Joseph F. Grosso; Timothy J. Harris; Hung-Rong Yen; Tullia C. Bruno; Satoshi Wada; Adam Adler; Robert W. Georgantas; Chunfa Jie; Monica V. Goldberg; Drew M. Pardoll; Charles G. Drake
J Immunol (2009) 182 (8): 4675–4685.
Inositol 1,4,5-Trisphosphate 3-Kinase B Is a Negative Regulator of BCR Signaling That Controls B Cell Selection and Tolerance Induction
J Immunol (2009) 182 (8): 4696–4704.
Nerve Growth Factor and Neurotrophin-3 Mediate Survival of Pulmonary Plasma Cells during the Allergic Airway Inflammation 1
Melanie Abram; Michael Wegmann; Verena Fokuhl; Sanchaita Sonar; Elke Olga Luger; Sebastian Kerzel; Andreas Radbruch; Harald Renz; Michael Zemlin
J Immunol (2009) 182 (8): 4705–4712.
The Generation of Influenza-Specific Humoral Responses Is Impaired in ST6Gal I-Deficient Mice 1
J Immunol (2009) 182 (8): 4721–4727.
Adaptive Immune Response in JAM-C-Deficient Mice: Normal Initiation but Reduced IgG Memory1
Claudia Zimmerli; Boris P. L. Lee; Gaby Palmer; Cem Gabay; Ralf Adams; Michel Aurrand-Lions; Beat A. Imhof
J Immunol (2009) 182 (8): 4728–4736.
IL-9 Promotes IL-13-Dependent Paneth Cell Hyperplasia and Up-Regulation of Innate Immunity Mediators in Intestinal Mucosa 1
Valérie Steenwinckel; Jamila Louahed; Muriel M. Lemaire; Caroline Sommereyns; Guy Warnier; Andrew McKenzie; Frank Brombacher; Jacques Van Snick; Jean-Christophe Renauld
J Immunol (2009) 182 (8): 4737–4743.
Association of HIV-Specific and Total CD8+ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point1
Wendy A. Burgers; Catherine Riou; Mandla Mlotshwa; Pholo Maenetje; Debra de Assis Rosa; Jason Brenchley; Koleka Mlisana; Daniel C. Douek; Richard Koup; Mario Roederer; Guy de Bruyn; Salim Abdool Karim; Carolyn Williamson; Clive M. Gray; and the CAPRISA 002 Acute Infection Study Team
J Immunol (2009) 182 (8): 4751–4761.
Drak2 Is Upstream of p70S6 Kinase: Its Implication in Cytokine-Induced Islet Apoptosis, Diabetes, and Islet Transplantation1
J Immunol (2009) 182 (8): 4762–4770.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Interaction of Bap31 and MHC Class I Molecules and Their Traffic Out of the Endoplasmic Reticulum 1
J Immunol (2009) 182 (8): 4776–4783.
Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments 1
J Immunol (2009) 182 (8): 4784–4791.
Evolution of the Ikaros Gene Family: Implications for the Origins of Adaptive Immunity 1
J Immunol (2009) 182 (8): 4792–4799.
Steric Hindrance and Fast Dissociation Explain the Lack of Immunogenicity of the Minor Histocompatibility HA-1Arg Null Allele 1
Eric Spierings; Stéphanie Gras; Jean-Baptiste Reiser; Bregje Mommaas; Mathilde Almekinders; Michel G. D. Kester; Anne Chouquet; Madalen Le Gorrec; Jan W. Drijfhout; Ferry Ossendorp; Dominique Housset; Els Goulmy
J Immunol (2009) 182 (8): 4809–4816.
Trimolecular Complex Formation of IgE, FcεRI, and a Recombinant Nonanaphylactic Single-Chain Antibody Fragment with High Affinity for IgE 1
Christian Lupinek; Kenneth H. Roux; Sylvia Laffer; Ingrid Rauter; Kavita Reginald; Michael Kneidinger; Katharina Blatt; Tanja Ball; Ines Pree; Beatrice Jahn-Schmid; Jean-Pierre Allam; Natalija Novak; Anja Drescher; Franz Kricek; Peter Valent; Hakan Englund; Rudolf Valenta
J Immunol (2009) 182 (8): 4817–4829.
N-Glycosylation Enhances Presentation of a MHC Class I-Restricted Epitope from Tyrosinase 1
J Immunol (2009) 182 (8): 4830–4835.
Thrombin Binding Predicts the Effects of Sequence Changes in a Human Monoclonal Antiphospholipid Antibody on Its In Vivo Biologic Actions 1
Ian Giles; Charis Pericleous; Xiaowei Liu; Jasmine Ehsanullah; Lindsey Clarke; Paul Brogan; Marvin Newton-West; Robert Swerlick; Anastasia Lambrianides; Pojen Chen; David Latchman; David Isenberg; Silvia Pierangeli; Anisur Rahman
J Immunol (2009) 182 (8): 4836–4843.
Critical and Multiple Roles for the CD3ε Intracytoplasmic Tail in Double Negative to Double Positive Thymocyte Differentiation 1
J Immunol (2009) 182 (8): 4844–4853.
HOST DEFENSE
Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway 1
J Immunol (2009) 182 (8): 4854–4864.
A Protective Role for Dengue Virus-Specific CD8+ T Cells 1
Lauren E. Yauch; Raphaël M. Zellweger; Maya F. Kotturi; Afrina Qutubuddin; John Sidney; Bjoern Peters; Tyler R. Prestwood; Alessandro Sette; Sujan Shresta
J Immunol (2009) 182 (8): 4865–4873.
Host-Derived Interleukin-1α Is Important in Determining the Immunogenicity of 3-Methylcholantrene Tumor Cells1
Moshe Elkabets; Yakov Krelin; Shahar Dotan; Adelheid Cerwenka; Angel Porgador; Rachel G. Lichtenstein; Malka R. White; Margot Zoller; Yoichizo Iwakura; Charles A. Dinarello; Elena Voronov; Ron N. Apte
J Immunol (2009) 182 (8): 4874–4881.
Protective Response to Leishmania major in BALB/c Mice Requires Antigen Processing in the Absence of DM 1
J Immunol (2009) 182 (8): 4882–4890.
Group V Secretory Phospholipase A2 Modulates Phagosome Maturation and Regulates the Innate Immune Response against Candida albicans1
J Immunol (2009) 182 (8): 4891–4898.
Differential Requirements for Protection against Mucosal Challenge with Francisella tularensis in the Presence versus Absence of Cholera Toxin B and Inactivated F. tularensis1
Constantine Bitsaktsis; Deepak B. Rawool; Ying Li; Nitin V. Kurkure; Bibiana Iglesias; Edmund J. Gosselin
J Immunol (2009) 182 (8): 4899–4909.
The NF-κB RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation
J Immunol (2009) 182 (8): 4910–4916.
Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae1
Christine Winter; Wiebke Herbold; Regina Maus; Florian Länger; David E. Briles; James C. Paton; Tobias Welte; Ulrich A. Maus
J Immunol (2009) 182 (8): 4931–4937.
INFLAMMATION
Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling 1
Qi-Quan Huang; Rudina Sobkoviak; Angela R. Jockheck-Clark; Bo Shi; Arthur M. Mandelin, II; Paul Peter Tak; G. Kennith Haines, III; Christopher V. Nicchitta; Richard M. Pope
J Immunol (2009) 182 (8): 4965–4973.
Formyl Peptide Receptor-Like 2 Is Expressed and Functional in Plasmacytoid Dendritic Cells, Tissue-Specific Macrophage Subpopulations, and Eosinophils 1
Thalie Devosse; Aude Guillabert; Nicky D'Haene; Alix Berton; Patricia De Nadai; Sophie Noel; Maryse Brait; Jean-Denis Franssen; Silvano Sozzani; Isabelle Salmon; Marc Parmentier
J Immunol (2009) 182 (8): 4974–4984.
Role of the Heparan Sulfate Proteoglycan Syndecan-1 (CD138) in Delayed-Type Hypersensitivity 1
Behzad Kharabi Masouleh; Gerdy B. Ten Dam; Martin K. Wild; Ruth Seelige; Johan van der Vlag; Angelique L. Rops; Frank G. Echtermeyer; Dietmar Vestweber; Toin H. van Kuppevelt; Ludwig Kiesel; Martin Götte
J Immunol (2009) 182 (8): 4985–4993.
MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression 1
J Immunol (2009) 182 (8): 4994–5002.
IL-20 Is Regulated by Hypoxia-Inducible Factor and Up-Regulated after Experimental Ischemic Stroke
J Immunol (2009) 182 (8): 5003–5012.
Functional Blocking Monoclonal Antibodies against IL-12p40 Homodimer Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis 1
J Immunol (2009) 182 (8): 5013–5023.
The Pattern Recognition Receptor CD36 Is a Chondrocyte Hypertrophy Marker Associated with Suppression of Catabolic Responses and Promotion of Repair Responses to Inflammatory Stimuli 1
Denise L. Cecil; C. Thomas G. Appleton; Monika D. Polewski; John S. Mort; Ann Marie Schmidt; Alison Bendele; Frank Beier; Robert Terkeltaub
J Immunol (2009) 182 (8): 5024–5031.
The Atypical Chemokine Receptor D6 Contributes to the Development of Experimental Colitis 1
Yvonne Bordon; Chris A. H. Hansell; David P. Sester; Mairi Clarke; Allan McI. Mowat; Robert J. B. Nibbs
J Immunol (2009) 182 (8): 5032–5040.
A Novel and Critical Role for Tyrosine 663 in Platelet Endothelial Cell Adhesion Molecule-1 Trafficking and Transendothelial Migration 1
J Immunol (2009) 182 (8): 5041–5051.
p53 Attenuates Lipopolysaccharide-Induced NF-κB Activation and Acute Lung Injury 1
J Immunol (2009) 182 (8): 5063–5071.
Mitocryptide-2: Purification, Identification, and Characterization of a Novel Cryptide That Activates Neutrophils 1
Hidehito Mukai; Tetsuo Seki; Hiroko Nakano; Yoshinori Hokari; Toshifumi Takao; Masanori Kawanami; Hiroyuki Tsukagoshi; Hirokazu Kimura; Yoshiaki Kiso; Yasutsugu Shimonishi; Yoshisuke Nishi; Eisuke Munekata
J Immunol (2009) 182 (8): 5072–5080.
Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes 1
J Immunol (2009) 182 (8): 5081–5087.
Bruton’s Tyrosine Kinase Is Involved in miR-346-Related Regulation of IL-18 Release by Lipopolysaccharide-Activated Rheumatoid Fibroblast-Like Synoviocytes 1
Ghada Alsaleh; Guillaume Suffert; Noha Semaan; Tom Juncker; Laurent Frenzel; Jacques-Eric Gottenberg; Jean Sibilia; Sébastien Pfeffer; Dominique Wachsmann
J Immunol (2009) 182 (8): 5088–5097.
Pathogenesis of Steroid-Resistant Airway Hyperresponsiveness: Interaction between IFN-γ and TLR4/MyD88 Pathways 1
J Immunol (2009) 182 (8): 5107–5115.
Induction of Airway Hyperreactivity by IL-25 Is Dependent on a Subset of Invariant NKT Cells Expressing IL-17RB 1
J Immunol (2009) 182 (8): 5116–5122.
CLINICAL IMMUNOLOGY
Enrichment of Human CD4+ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors 1
Gabriel Bricard; Valerie Cesson; Estelle Devevre; Hanifa Bouzourene; Catherine Barbey; Nathalie Rufer; Jin S. Im; Pedro M. Alves; Olivier Martinet; Nermin Halkic; Jean-Charles Cerottini; Pedro Romero; Steven A. Porcelli; H. Robson MacDonald; Daniel E. Speiser
J Immunol (2009) 182 (8): 5140–5151.
CORRECTIONS
Linking C5 deficiency to an exonic splicing enhancer mutation
N. Pfarr; D. Prawitt; M. Kirschfink; C. Schroff; M. Knuf; P. Habermehl; W. Mannhardt; F. Zepp; W. Fairbrother; M. Loos; C. B. Burge; J. Pohlenz
J Immunol (2009) 182 (8): 5152.
Extracellular granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo
E. H. A. Spaeny-Dekking; W. L. Hanna; A. M. Wolbink; P. C. Wever; A. J. Kummer; A. J. G. Swaak; J. M. Middeldorp; H. G. Huisman; C. J. Froelich; C. E. Hack
J Immunol (2009) 182 (8): 5152.
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Cover Image
Cover Image
On the cover: Dendritic cells (DC) infected with Leishmania major are stained with Giemsa. The dark purple large mass in each DC is the host cell nucleus and smaller dots are the nuclei of intracellular L. major. DM-deficient BALB/c mice are resistant to L. major infections whereas the wild-type mice are susceptible even though the parasite can infect the wild-type and DM−/− DC in a comparable manner. Kamala, T., and N. Nanda. 2009. Protective response to Leishmania major in BALB/c mice requires antigen processing in the absence of DM. J. Immunol. 182: 4882–4890.
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