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J Immunol (2009) 183 (11): 6857–6858.

View articletitled, IN THIS ISSUE

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LETTERS TO THE EDITOR

Comment on “TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions”

Christian Bogdan; Ulrike Schleicher

J Immunol (2009) 183 (11): 6859.

View articletitled, Comment on “TLR9-Dependent Activation of Dendritic Cells by DNA from <em>Leishmania major</em> Favors Th1 Cell Development and the Resolution of Lesions”

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Response to Comment on “TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions”

Noëlle Doyen

J Immunol (2009) 183 (11): 6859.

View articletitled, Response to Comment on “TLR9-Dependent Activation of Dendritic Cells by DNA from <em>Leishmania major</em> Favors Th1 Cell Development and the Resolution of Lesions”

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PILLARS OF IMMUNOLOGY

A Crucial Door to the Mast Cell Mystery Knocked In

Toshiaki Kawakami

J Immunol (2009) 183 (11): 6861–6862.

View articletitled, A Crucial Door to the Mast Cell Mystery Knocked In

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Pillars Article: Fate of Bone Marrow-Derived Cultured Mast Cells After Intracutaneous, Intraperitoneal, And Intravenous Transfer Into Genetically Mast Cell-Deficient W/Wv Mice. Evidence That Cultured Mast Cells Can Give Rise To Both Connective Tissue Type And Mucosal Mast Cells. The Journal of Experimental Medicine. 1985. 162: 1025–1043

Toru Nakano; Takashi Sonoda; Chieko Hayashi; Atsushi Yamatodani; Yoshio Kanayama; Tei-Ichi Yamamura; Hidekazu Asai; Takeshi Yonezawa; Yukihiko Kitamura; Stephen J. Galli

J Immunol (2009) 183 (11): 6863–6881.

View articletitled, Pillars Article: Fate of Bone Marrow-Derived Cultured Mast Cells After Intracutaneous, Intraperitoneal, And Intravenous Transfer Into Genetically Mast Cell-Deficient W/Wv Mice. Evidence That Cultured Mast Cells Can Give Rise To Both Connective Tissue Type And Mucosal Mast Cells. <em>The Journal of Experimental Medicine</em>. 1985. 162: 1025–1043

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BRIEF REVIEWS

What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?

Igor M. Belyakov; Jeffrey D. Ahlers

J Immunol (2009) 183 (11): 6883–6892.

View articletitled, What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?

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CUTTING EDGE

Cutting Edge: Requirement of MARCH-I-Mediated MHC II Ubiquitination for the Maintenance of Conventional Dendritic Cells ¹

Mari Ohmura-Hoshino; Yohei Matsuki; Mari Mito-Yoshida; Eiji Goto; Masami Aoki-Kawasumi; Manabu Nakayama; Osamu Ohara; Satoshi Ishido

J Immunol (2009) 183 (11): 6893–6897.

View articletitled, Cutting Edge: Requirement of MARCH-I-Mediated MHC II Ubiquitination for the Maintenance of Conventional Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: Memory CD8 T Cell Compartment Grows in Size with Immunological Experience but Nevertheless Can Lose Function ¹

Katharina M. Huster; Christian Stemberger; Georg Gasteiger; Wolfgang Kastenmüller; Ingo Drexler; Dirk H. Busch

J Immunol (2009) 183 (11): 6898–6902.

View articletitled, Cutting Edge: Memory CD8 T Cell Compartment Grows in Size with Immunological Experience but Nevertheless Can Lose Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Peroxisome Proliferator-Activated Receptor γ Ligands Enhance Human B Cell Antibody Production and Differentiation ¹

Tatiana M. Garcia-Bates; Carolyn J. Baglole; Matthew P. Bernard; Thomas I. Murant; Patricia J. Simpson-Haidaris; Richard P. Phipps

J Immunol (2009) 183 (11): 6903–6912.

View articletitled, Peroxisome Proliferator-Activated Receptor γ Ligands Enhance Human B Cell Antibody Production and Differentiation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Impaired NK Cytolytic Activity and Enhanced Tumor Growth in NK Lytic-Associated Molecule-Deficient Mice ¹^²

Richard G. Hoover; Gail Gullickson; Jacki Kornbluth

J Immunol (2009) 183 (11): 6913–6921.

View articletitled, Impaired NK Cytolytic Activity and Enhanced Tumor Growth in NK Lytic-Associated Molecule-Deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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NOD2 Ligation Subverts IFN-α Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation ¹

Antonino Castellaneta; Tina L. Sumpter; Lieping Chen; Daisuke Tokita; Angus W. Thomson

J Immunol (2009) 183 (11): 6922–6932.

View articletitled, NOD2 Ligation Subverts IFN-α Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Intranasal Immunization Promotes Th17 Immune Responses ¹

Beata M. Zygmunt; Faiza Rharbaoui; Lothar Groebe; Carlos A. Guzman

J Immunol (2009) 183 (11): 6933–6938.

View articletitled, Intranasal Immunization Promotes Th17 Immune Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment ¹

Amorette Barber; Agnieszka Rynda; Charles L. Sentman

J Immunol (2009) 183 (11): 6939–6947.

View articletitled, Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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RREB-1 Is a Transcriptional Repressor of HLA-G ¹

Sébastien Flajollet; Isabelle Poras; Edgardo D. Carosella; Philippe Moreau

J Immunol (2009) 183 (11): 6948–6959.

View articletitled, RREB-1 Is a Transcriptional Repressor of HLA-G<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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TLR2 Promotes Th2/Th17 Responses via TLR4 and TLR7/8 by Abrogating the Type I IFN Amplification Loop ¹

Mark H. Wenink; Kim C. M. Santegoets; Jacobus C. A. Broen; Lenny van Bon; Shahla Abdollahi-Roodsaz; Calin Popa; Richard Huijbens; Thijs Remijn; Erik Lubberts; Piet L. C. M. van Riel; Wim B. van den Berg; Timothy R. D. J. Radstake

J Immunol (2009) 183 (11): 6960–6970.

View articletitled, TLR2 Promotes Th2/Th17 Responses via TLR4 and TLR7/8 by Abrogating the Type I IFN Amplification Loop<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Innate Immune CD11b⁺Gr-1⁺ Cells, Suppressor Cells, Affect the Immune Response during Theiler’s Virus-Induced Demyelinating Disease ¹

Jenna L. Bowen; Julie K. Olson

J Immunol (2009) 183 (11): 6971–6980.

View articletitled, Innate Immune CD11b<sup>+</sup>Gr-1<sup>+</sup> Cells, Suppressor Cells, Affect the Immune Response during Theiler’s Virus-Induced Demyelinating Disease<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Prostacyclin Inhibits IFN-γ-Stimulated Cytokine Expression by Reduced Recruitment of CBP/p300 to STAT1 in a SOCS-1-Independent Manner ¹

Derek Strassheim; Suzzette R. Riddle; Danielle L. Burke; Mark W. Geraci; Kurt R. Stenmark

J Immunol (2009) 183 (11): 6981–6988.

View articletitled, Prostacyclin Inhibits IFN-γ-Stimulated Cytokine Expression by Reduced Recruitment of CBP/p300 to STAT1 in a SOCS-1-Independent Manner<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses ¹

Qiong Wang; Deepti R. Nagarkar; Emily R. Bowman; Dina Schneider; Babina Gosangi; Jing Lei; Ying Zhao; Christina L. McHenry; Richai V. Burgens; David J. Miller; Umadevi Sajjan; Marc B. Hershenson

J Immunol (2009) 183 (11): 6989–6997.

View articletitled, Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Estrogen Regulates Transcription Factors STAT-1 and NF-κB to Promote Inducible Nitric Oxide Synthase and Inflammatory Responses ¹

Rujuan Dai; Rebecca A. Phillips; Ebru Karpuzoglu; Deena Khan; S. Ansar Ahmed

J Immunol (2009) 183 (11): 6998–7005.

View articletitled, Estrogen Regulates Transcription Factors STAT-1 and NF-κB to Promote Inducible Nitric Oxide Synthase and Inflammatory Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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IL-9 Regulates Pathology during Primary and Memory Responses to Respiratory Syncytial Virus Infection ¹

Jonathan S. Dodd; Eda Lum; John Goulding; Roshell Muir; Jacques Van Snick; Peter J. M. Openshaw

J Immunol (2009) 183 (11): 7006–7013.

View articletitled, IL-9 Regulates Pathology during Primary and Memory Responses to Respiratory Syncytial Virus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Limited Role of CD4⁺Foxp3⁺ Regulatory T Cells in the Control of Experimental Cerebral Malaria ¹

Christiane Steeg; Guido Adler; Tim Sparwasser; Bernhard Fleischer; Thomas Jacobs

J Immunol (2009) 183 (11): 7014–7022.

View articletitled, Limited Role of CD4<sup>+</sup>Foxp3<sup>+</sup> Regulatory T Cells in the Control of Experimental Cerebral Malaria<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Systemic Increase in the Ratio between Foxp3⁺ and IL-17-Producing CD4⁺ T Cells in Healthy Pregnancy but Not in Preeclampsia ¹

Brigitte Santner-Nanan; Michael John Peek; Roma Khanam; Luise Richarts; Erhua Zhu; Barbara Fazekas de St Groth; Ralph Nanan

J Immunol (2009) 183 (11): 7023–7030.

View articletitled, Systemic Increase in the Ratio between Foxp3<sup>+</sup> and IL-17-Producing CD4<sup>+</sup> T Cells in Healthy Pregnancy but Not in Preeclampsia<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Female and Male Sex Hormones Differentially Regulate Expression of Ifi202, an Interferon-Inducible Lupus Susceptibility Gene within the Nba2 Interval ¹

Ravichandran Panchanathan; Hui Shen; Melanie Gubbels Bupp; Karen A. Gould; Divaker Choubey

J Immunol (2009) 183 (11): 7031–7038.

View articletitled, Female and Male Sex Hormones Differentially Regulate Expression of <em>Ifi202</em>, an Interferon-Inducible Lupus Susceptibility Gene within the <em>Nba2</em> Interval<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Absence of the Transcriptional Repressor Blimp-1 in Hematopoietic Lineages Reveals Its Role in Dendritic Cell Homeostatic Development and Function ¹

Yueh-Hsuan Chan; Ming-Feng Chiang; Yueh-Chiao Tsai; Shin-Tang Su; Ming-Hsu Chen; Mau-Sheng Hou; Kuo-I Lin

J Immunol (2009) 183 (11): 7039–7046.

View articletitled, Absence of the Transcriptional Repressor Blimp-1 in Hematopoietic Lineages Reveals Its Role in Dendritic Cell Homeostatic Development and Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis ¹

Mako Nakaya; Masayuki Hashimoto; Ryusuke Nakagawa; Yu Wakabayashi; Takuma Ishizaki; Ichiro Takada; Kyoko Komai; Hiroki Yoshida; Akihiko Yoshimura

J Immunol (2009) 183 (11): 7047–7053.

View articletitled, SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cells Secrete the Immunosuppressive HLA-G Molecule upon CTLA4-Ig Treatment: Implication in Human Renal Transplant Acceptance ¹

Rajia Bahri; Abderrahim Naji; Catherine Menier; Bernard Charpentier; Edgardo D. Carosella; Nathalie Rouas-Freiss; Antoine Durrbach

J Immunol (2009) 183 (11): 7054–7062.

View articletitled, Dendritic Cells Secrete the Immunosuppressive HLA-G Molecule upon CTLA4-Ig Treatment: Implication in Human Renal Transplant Acceptance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression ¹

Torsten Juelich; Elissa Sutcliffe; Alice Denton; Yiqing He; Peter C. Doherty; Christopher Parish; Steven J. Turner; David Tremethick; Sudha Rao

J Immunol (2009) 183 (11): 7063–7072.

View articletitled, Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases ¹

Annette Duelli; Elin Rönnberg; Ida Waern; Maria Ringvall; Svein O. Kolset; Gunnar Pejler

J Immunol (2009) 183 (11): 7073–7083.

View articletitled, Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Sex Steroid Ablation Enhances Hematopoietic Recovery following Cytotoxic Antineoplastic Therapy in Aged Mice ¹

Jarrod A. Dudakov; Gabrielle L. Goldberg; Jessica J. Reiseger; Katerina Vlahos; Ann P. Chidgey; Richard L. Boyd

J Immunol (2009) 183 (11): 7084–7094.

View articletitled, Sex Steroid Ablation Enhances Hematopoietic Recovery following Cytotoxic Antineoplastic Therapy in Aged Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dendritic Cells Matured by Inflammation Induce CD86-Dependent Priming of Naive CD8⁺ T Cells in the Absence of Their Cognate Peptide Antigen ¹

Asher Maroof; Lynette Beattie; Alun Kirby; Mark Coles; Paul M. Kaye

J Immunol (2009) 183 (11): 7095–7103.

View articletitled, Dendritic Cells Matured by Inflammation Induce CD86-Dependent Priming of Naive CD8<sup>+</sup> T Cells in the Absence of Their Cognate Peptide Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Apoptotic Dendritic Cells Induce Tolerance in Mice through Suppression of Dendritic Cell Maturation and Induction of Antigen-Specific Regulatory T Cells ¹

Rahul Kushwah; Jordan R. Oliver; Jinyi Zhang; Katherine A. Siminovitch; Jim Hu

J Immunol (2009) 183 (11): 7104–7118.

View articletitled, Apoptotic Dendritic Cells Induce Tolerance in Mice through Suppression of Dendritic Cell Maturation and Induction of Antigen-Specific Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Deciphering the Immune Function and Regulation by a TLR of the Cytokine EMAPII in the Lesioned Central Nervous System Using a Leech Model ¹^²

David Schikorski; Virginie Cuvillier-Hot; Céline Boidin-Wichlacz; Christian Slomianny; Michel Salzet; Aurélie Tasiemski

J Immunol (2009) 183 (11): 7119–7128.

View articletitled, Deciphering the Immune Function and Regulation by a TLR of the Cytokine EMAPII in the Lesioned Central Nervous System Using a Leech Model<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Dominant Expression of the Inhibitory FcγRIIB Prevents Antigen Presentation by Murine Plasmacytoid Dendritic Cells ¹

Marcella Flores; Dharmesh D. Desai; Matthew Downie; Bitao Liang; Michael P. Reilly; Steven E. McKenzie; Raphael Clynes

J Immunol (2009) 183 (11): 7129–7139.

View articletitled, Dominant Expression of the Inhibitory FcγRIIB Prevents Antigen Presentation by Murine Plasmacytoid Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Plasmacytoid Dendritic Cells Regulate Autoreactive B Cell Activation via Soluble Factors and in a Cell-to-Cell Contact Manner ¹

Chuanlin Ding; Yihua Cai; Jose Marroquin; Suzanne T. Ildstad; Jun Yan

J Immunol (2009) 183 (11): 7140–7149.

View articletitled, Plasmacytoid Dendritic Cells Regulate Autoreactive B Cell Activation via Soluble Factors and in a Cell-to-Cell Contact Manner<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults ¹

Tobias R. Kollmann; Juliet Crabtree; Annie Rein-Weston; Darren Blimkie; Francis Thommai; Xiu Yu Wang; Pascal M. Lavoie; Jeff Furlong; Edgardo S. Fortuno, III; Adeline M. Hajjar; Natalie R. Hawkins; Steven G. Self; Christopher B. Wilson

J Immunol (2009) 183 (11): 7150–7160.

View articletitled, Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity ¹

Hung-Rong Yen; Timothy J. Harris; Satoshi Wada; Joseph F. Grosso; Derese Getnet; Monica V. Goldberg; Kai-Li Liang; Tullia C. Bruno; Kristin J. Pyle; Siaw-Li Chan; Robert A. Anders; Cornelia L. Trimble; Adam J. Adler; Tzou-Yien Lin; Drew M. Pardoll; Ching-Tai Huang; Charles G. Drake

J Immunol (2009) 183 (11): 7161–7168.

View articletitled, Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes ¹

Anneli Jäger; Valérie Dardalhon; Raymond A. Sobel; Estelle Bettelli; Vijay K. Kuchroo

J Immunol (2009) 183 (11): 7169–7177.

View articletitled, Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Recruitment of Sprouty1 to Immune Synapse Regulates T Cell Receptor Signaling ¹

Jun Sung Lee; Ji Eun Lee; Yu Mi Oh; Jong Bae Park; Heonsik Choi; Chung Yeon Choi; In-Hoo Kim; Seung Hoon Lee; Kyungho Choi

J Immunol (2009) 183 (11): 7178–7186.

View articletitled, Recruitment of Sprouty1 to Immune Synapse Regulates T Cell Receptor Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Processing in the Endoplasmic Reticulum Generates an Epitope on the Insulin A Chain that Stimulates Diabetogenic CD8 T Cell Responses ¹

Helen Brosi; Michael Reiser; Tarvo Rajasalu; Andreas Spyrantis; Franz Oswald; Bernhard Otto Boehm; Reinhold Schirmbeck

J Immunol (2009) 183 (11): 7187–7195.

View articletitled, Processing in the Endoplasmic Reticulum Generates an Epitope on the Insulin A Chain that Stimulates Diabetogenic CD8 T Cell Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation ¹

Alexander Filatenkov; Antonia M. S. Müller; William Wei-Lin Tseng; Sussan Dejbakhsh-Jones; Daniel Winer; Richard Luong; Judith A. Shizuru; Edgar G. Engleman; Samuel Strober

J Immunol (2009) 183 (11): 7196–7203.

View articletitled, Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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P-Selectin Glycoprotein Ligand-1 Negatively Regulates T-Cell Immune Responses ¹

Masanori Matsumoto; Masayuki Miyasaka; Takako Hirata

J Immunol (2009) 183 (11): 7204–7211.

View articletitled, P-Selectin Glycoprotein Ligand-1 Negatively Regulates T-Cell Immune Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies ¹

Emma Fiorini; Estelle Merck; Anne Wilson; Isabel Ferrero; Wei Jiang; Ute Koch; Floriane Auderset; Elisa Laurenti; Fabienne Tacchini-Cottier; Michel Pierres; Freddy Radtke; Sanjiv A. Luther; H. Robson MacDonald

J Immunol (2009) 183 (11): 7212–7222.

View articletitled, Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN-γ in Human Osteoclast Precursors ¹

Jong-Dae Ji; Kyung-Hyun Park-Min; Zenxin Shen; Roberto J. Fajardo; Steven R. Goldring; Kevin P. McHugh; Lionel B. Ivashkiv

J Immunol (2009) 183 (11): 7223–7233.

View articletitled, Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN-γ in Human Osteoclast Precursors<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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SHP-2 Expression Negatively Regulates NK Cell Function ¹

Amanda K. Purdy; Kerry S. Campbell

J Immunol (2009) 183 (11): 7234–7243.

View articletitled, SHP-2 Expression Negatively Regulates NK Cell Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MHC Drives TCR Repertoire Shaping, but not Maturation, in Recent Thymic Emigrants ¹^²

Evan G. Houston, Jr.; Pamela J. Fink

J Immunol (2009) 183 (11): 7244–7249.

View articletitled, MHC Drives TCR Repertoire Shaping, but not Maturation, in Recent Thymic Emigrants<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Ectopic T-bet Expression Licenses Dendritic Cells for IL-12-Independent Priming of Type 1 T Cells In Vitro ¹

Michael W. Lipscomb; Lu Chen; Jennifer L. Taylor; Christina Goldbach; Simon C. Watkins; Pawel Kalinski; Lisa H. Butterfield; Amy K. Wesa; Walter J. Storkus

J Immunol (2009) 183 (11): 7250–7258.

View articletitled, Ectopic T-bet Expression Licenses Dendritic Cells for IL-12-Independent Priming of Type 1 T Cells In Vitro<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis ¹

Ann J. Canonigo-Balancio; Camille Fos; Thomas Prod'homme; Stéphane Bécart; Amnon Altman

J Immunol (2009) 183 (11): 7259–7267.

View articletitled, SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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A Nonadjuvanted Polypeptide Nanoparticle Vaccine Confers Long-Lasting Protection against Rodent Malaria ¹

Stephen A. Kaba; Clara Brando; Qin Guo; Christian Mittelholzer; Senthilkumar Raman; David Tropel; Ueli Aebi; Peter Burkhard; David E. Lanar

J Immunol (2009) 183 (11): 7268–7277.

View articletitled, A Nonadjuvanted Polypeptide Nanoparticle Vaccine Confers Long-Lasting Protection against Rodent Malaria<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium

Michiyuki Kasai; Isei Tanida; Takashi Ueno; Eiki Kominami; Sachiko Seki; Tohru Ikeda; Toshiaki Mizuochi

J Immunol (2009) 183 (11): 7278–7285.

View articletitled, Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium

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T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment ¹

Timothy C. Cheung; Lisa M. Oborne; Marcos W. Steinberg; Matthew G. Macauley; Satoshi Fukuyama; Hideki Sanjo; Claire D'Souza; Paula S. Norris; Klaus Pfeffer; Kenneth M. Murphy; Mitchell Kronenberg; Patricia G. Spear; Carl F. Ware

J Immunol (2009) 183 (11): 7286–7296.

View articletitled, T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Role of T Cell TGFβ Signaling and IL-17 in Allograft Acceptance and Fibrosis Associated with Chronic Rejection ¹

Susan M. Faust; Guanyi Lu; Bernard L. Marini; Weiping Zou; David Gordon; Yoichiro Iwakura; Yasmina Laouar; D. Keith Bishop

J Immunol (2009) 183 (11): 7297–7306.

View articletitled, Role of T Cell TGFβ Signaling and IL-17 in Allograft Acceptance and Fibrosis Associated with Chronic Rejection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TGFβ Neutralization within Cardiac Allografts by Decorin Gene Transfer Attenuates Chronic Rejection ¹

Susan M. Faust; Guanyi Lu; Sherri C. Wood; D. Keith Bishop

J Immunol (2009) 183 (11): 7307–7313.

View articletitled, TGFβ Neutralization within Cardiac Allografts by Decorin Gene Transfer Attenuates Chronic Rejection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Taking Advantage: High-Affinity B Cells in the Germinal Center Have Lower Death Rates, but Similar Rates of Division, Compared to Low-Affinity Cells ¹

Shannon M. Anderson; Ashraf Khalil; Mohamed Uduman; Uri Hershberg; Yoram Louzoun; Ann M. Haberman; Steven H. Kleinstein; Mark J. Shlomchik

J Immunol (2009) 183 (11): 7314–7325.

View articletitled, Taking Advantage: High-Affinity B Cells in the Germinal Center Have Lower Death Rates, but Similar Rates of Division, Compared to Low-Affinity Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Endogenous IL-21 Restricts CD8⁺ T Cell Expansion and Is not Required for Tumor Immunity ¹

Henrik Søndergaard; Jonathan M. Coquet; Adam P. Uldrich; Nicole McLaughlin; Dale I. Godfrey; Pallavur V. Sivakumar; Kresten Skak; Mark J. Smyth

J Immunol (2009) 183 (11): 7326–7336.

View articletitled, Endogenous IL-21 Restricts CD8<sup>+</sup> T Cell Expansion and Is not Required for Tumor Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers ¹

Laura Martínez Muñoz; Pilar Lucas; Gemma Navarro; Ana I. Checa; Rafael Franco; Carlos Martínez-A.; José Miguel Rodríguez-Frade; Mario Mellado

J Immunol (2009) 183 (11): 7337–7346.

View articletitled, Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Coexistence of Closed and Open Conformations of Complement Factor B in the Alternative Pathway C3bB(Mg²⁺) Proconvertase ¹^²

Eva Torreira; Agustín Tortajada; Tamara Montes; Santiago Rodríguez de Córdoba; Oscar Llorca

J Immunol (2009) 183 (11): 7347–7351.

View articletitled, Coexistence of Closed and Open Conformations of Complement Factor B in the Alternative Pathway C3bB(Mg<sup>2+</sup>) Proconvertase<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase Cγ1 Microcluster Dynamics during T Cell Spreading ¹

Esteban Carrizosa; Timothy S. Gomez; Christine M. Labno; Deborah A. Klos Dehring; Xiaohong Liu; Bruce D. Freedman; Daniel D. Billadeau; Janis K. Burkhardt

J Immunol (2009) 183 (11): 7352–7361.

View articletitled, Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase Cγ1 Microcluster Dynamics during T Cell Spreading<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes ¹

Miguel E. Moreno-García; Karen Sommer; Claudia Haftmann; Clayton Sontheimer; Sarah F. Andrews; David J. Rawlings

J Immunol (2009) 183 (11): 7362–7370.

View articletitled, Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation ¹

Søren E. Degn; Annette G. Hansen; Rudi Steffensen; Christian Jacobsen; Jens C. Jensenius; Steffen Thiel

J Immunol (2009) 183 (11): 7371–7378.

View articletitled, MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cytosolic Aminopeptidases Influence MHC Class I-Mediated Antigen Presentation in an Allele-Dependent Manner ¹

Eunkyung Kim; Heechun Kwak; Kwangseog Ahn

J Immunol (2009) 183 (11): 7379–7387.

View articletitled, Cytosolic Aminopeptidases Influence MHC Class I-Mediated Antigen Presentation in an Allele-Dependent Manner<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells ¹

Robert J. Salmond; Juliet Emery; Klaus Okkenhaug; Rose Zamoyska

J Immunol (2009) 183 (11): 7388–7397.

View articletitled, MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

The DC-SIGN of Zebrafish: Insights into the Existence of a CD209 Homologue in a Lower Vertebrate and Its Involvement in Adaptive Immunity ¹

Ai-Fu Lin; Li-Xin Xiang; Qu-Long Wang; Wei-Ren Dong; Yong-Feng Gong; Jian-Zhong Shao

J Immunol (2009) 183 (11): 7398–7410.

View articletitled, The DC-SIGN of Zebrafish: Insights into the Existence of a CD209 Homologue in a Lower Vertebrate and Its Involvement in Adaptive Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HOST DEFENSE

Increased Inflammation, Impaired Bacterial Clearance, and Metabolic Disruption after Gram-Negative Sepsis in Mkp-1-Deficient Mice ¹

W. Joshua Frazier; Xianxi Wang; Lyn M. Wancket; Xiang-An Li; Xiaomei Meng; Leif D. Nelin; Andrew C. B. Cato; Yusen Liu

J Immunol (2009) 183 (11): 7411–7419.

View articletitled, Increased Inflammation, Impaired Bacterial Clearance, and Metabolic Disruption after Gram-Negative Sepsis in <em>Mkp-1</em>-Deficient Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Early Response of Mucosal Epithelial Cells during Toxoplasma gondii Infection

Chia-Hsin Ju; Annapoorani Chockalingam; Cynthia A. Leifer

J Immunol (2009) 183 (11): 7420–7427.

View articletitled, Early Response of Mucosal Epithelial Cells during <em>Toxoplasma gondii</em> Infection

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Immune Gene and Cell Enrichment Is Associated with a Good Prognosis in Ependymoma ¹

Andrew M. Donson; Diane K. Birks; Valerie N. Barton; Qi Wei; Bette K. Kleinschmidt-DeMasters; Michael H. Handler; Allen E. Waziri; Michael Wang; Nicholas K. Foreman

J Immunol (2009) 183 (11): 7428–7440.

View articletitled, Immune Gene and Cell Enrichment Is Associated with a Good Prognosis in Ependymoma<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection ¹

Michelle D. Tate; Yi-Mo Deng; Jessica E. Jones; Gary P. Anderson; Andrew G. Brooks; Patrick C. Reading

J Immunol (2009) 183 (11): 7441–7450.

View articletitled, Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification of Lipoteichoic Acid as a Ligand for Draper in the Phagocytosis of Staphylococcus aureus by Drosophila Hemocytes ¹

Yumi Hashimoto; Yukichika Tabuchi; Kenji Sakurai; Mayumi Kutsuna; Kenji Kurokawa; Takeshi Awasaki; Kazuhisa Sekimizu; Yoshinobu Nakanishi; Akiko Shiratsuchi

J Immunol (2009) 183 (11): 7451–7460.

View articletitled, Identification of Lipoteichoic Acid as a Ligand for Draper in the Phagocytosis of <em>Staphylococcus aureus</em> by <em>Drosophila</em> Hemocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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INFLAMMATION

TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients ¹

Madhumita Jagannathan; Hatice Hasturk; YanMei Liang; Hyunjin Shin; Jeremy T. Hetzel; Alpdogan Kantarci; Daniel Rubin; Marie E. McDonnell; Thomas E. Van Dyke; Lisa M. Ganley-Leal; Barbara S. Nikolajczyk

J Immunol (2009) 183 (11): 7461–7470.

View articletitled, TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner ¹

Xiaoyang Wang; Linnea Stridh; Wenli Li; Justin Dean; Anders Elmgren; Liming Gan; Kristina Eriksson; Henrik Hagberg; Carina Mallard

J Immunol (2009) 183 (11): 7471–7477.

View articletitled, Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CCR5 Ligands Modulate CXCL12-Induced Chemotaxis, Adhesion, and Akt Phosphorylation of Human Cord Blood CD34⁺ Cells ¹

Sunanda Basu; Hal E. Broxmeyer

J Immunol (2009) 183 (11): 7478–7488.

View articletitled, CCR5 Ligands Modulate CXCL12-Induced Chemotaxis, Adhesion, and Akt Phosphorylation of Human Cord Blood CD34<sup>+</sup> Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Oxazolidinone Derivative Locostatin Induces Cytokine Appeasement ¹

Antoine Ménoret; Jeremy P. McAleer; Soo-Mun Ngoi; Swagatam Ray; Nicholas A. Eddy; Gabriel Fenteany; Seung-Joo Lee; Robert J. Rossi; Bijay Mukherji; David L. Allen; Nitya G. Chakraborty; Anthony T. Vella

J Immunol (2009) 183 (11): 7489–7496.

View articletitled, The Oxazolidinone Derivative Locostatin Induces Cytokine Appeasement<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Calcium-Independent Phospholipase A₂β-Akt Signaling Is Involved in Lipopolysaccharide-Induced NADPH Oxidase 1 Expression and Foam Cell Formation ¹

Sun-Hye Lee; Dae-Weon Park; Sung Chul Park; Yun-Ki Park; Seong Yeon Hong; Jae-Ryong Kim; Chu-Hee Lee; Suk-Hwan Baek

J Immunol (2009) 183 (11): 7497–7504.

View articletitled, Calcium-Independent Phospholipase A<sub>2</sub>β-Akt Signaling Is Involved in Lipopolysaccharide-Induced NADPH Oxidase 1 Expression and Foam Cell Formation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD80 Blockade Enhance Glucocorticoid-Induced Leucine Zipper Expression and Suppress Experimental Autoimmune Encephalomyelitis ¹

Shailesh P. Dudhgaonkar; Srihari B. Janardhanam; Krithika N. Kodumudi; Mythily Srinivasan

J Immunol (2009) 183 (11): 7505–7513.

View articletitled, CD80 Blockade Enhance Glucocorticoid-Induced Leucine Zipper Expression and Suppress Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation ¹

J Immunol (2009) 183 (11): 7514–7522.

View articletitled, G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Natural Occurring IL-17 Producing T Cells Regulate the Initial Phase of Neutrophil Mediated Airway Responses ¹

Shinya Tanaka; Takayuki Yoshimoto; Tetsuji Naka; Susumu Nakae; Yo-ichi Iwakura; Daniel Cua; Masato Kubo

J Immunol (2009) 183 (11): 7523–7530.

View articletitled, Natural Occurring IL-17 Producing T Cells Regulate the Initial Phase of Neutrophil Mediated Airway Responses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Fms-Like Tyrosine Kinase 3 Ligand Regulates Migratory Pattern and Antigen Uptake of Lung Dendritic Cell Subsets in a Murine Model of Allergic Airway Inflammation ¹

Zhifei Shao; Toluwalope O. Makinde; Halvor S. McGee; Xiang Wang; Devendra K. Agrawal

J Immunol (2009) 183 (11): 7531–7538.

View articletitled, Fms-Like Tyrosine Kinase 3 Ligand Regulates Migratory Pattern and Antigen Uptake of Lung Dendritic Cell Subsets in a Murine Model of Allergic Airway Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis ¹

Akiko Oyamada; Hiori Ikebe; Momoe Itsumi; Hirokazu Saiwai; Seiji Okada; Kazuya Shimoda; Yoichiro Iwakura; Keiichi I. Nakayama; Yukihide Iwamoto; Yasunobu Yoshikai; Hisakata Yamada

J Immunol (2009) 183 (11): 7539–7546.

View articletitled, Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Unlike Th1, Th17 Cells Mediate Sustained Autoimmune Inflammation and Are Highly Resistant to Restimulation-Induced Cell Death ¹

Guangpu Shi; Madhu Ramaswamy; Barbara P. Vistica; Catherine A. Cox; Cuiyan Tan; Eric F. Wawrousek; Richard M. Siegel; Igal Gery

J Immunol (2009) 183 (11): 7547–7556.

View articletitled, Unlike Th1, Th17 Cells Mediate Sustained Autoimmune Inflammation and Are Highly Resistant to Restimulation-Induced Cell Death<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Selective Down-Regulation of Neutrophil Mac-1 in Endotoxemic Hepatic Microcirculation via IL-10 ¹

Gustavo Batista Menezes; Woo-Yong Lee; Hong Zhou; Christopher Curtis Matchett Waterhouse; Denise Carmona Cara; Paul Kubes

J Immunol (2009) 183 (11): 7557–7568.

View articletitled, Selective Down-Regulation of Neutrophil Mac-1 in Endotoxemic Hepatic Microcirculation via IL-10<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Systematic Classification of Primary Immunodeficiencies Based on Clinical, Pathological, and Laboratory Parameters ¹

Crina Samarghitean; Csaba Ortutay; Mauno Vihinen

J Immunol (2009) 183 (11): 7569–7575.

View articletitled, Systematic Classification of Primary Immunodeficiencies Based on Clinical, Pathological, and Laboratory Parameters<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics ¹

Chris Pickard; Fethi Louafi; Carolann McGuire; Kelly Lowings; Pawan Kumar; Hywel Cooper; Rebecca J. Dearman; Marie Cumberbatch; Ian Kimber; Eugene Healy; Peter S. Friedmann

J Immunol (2009) 183 (11): 7576–7584.

View articletitled, The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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β Cell-Specific CD4⁺ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct ¹

Li Li; Qiuming He; Alaina Garland; Zuoan Yi; Lydia T. Aybar; Thomas B. Kepler; Jeffrey A. Frelinger; Bo Wang; Roland Tisch

J Immunol (2009) 183 (11): 7585–7591.

View articletitled, β Cell-Specific CD4<sup>+</sup> T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Immunomodulation of Nasal Epithelial Cells by Staphylococcus aureus-Derived Serine Proteases ¹

Claudia Rudack; Florian Sachse; Nils Albert; Karsten Becker; Christof von Eiff

J Immunol (2009) 183 (11): 7592–7601.

View articletitled, Immunomodulation of Nasal Epithelial Cells by <em>Staphylococcus aureus</em>-Derived Serine Proteases<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD39⁺Foxp3⁺ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis ¹

Jean M. Fletcher; Roisin Lonergan; Lisa Costelloe; Katie Kinsella; Barry Moran; Cliona O'Farrelly; Niall Tubridy; Kingston H. G. Mills

J Immunol (2009) 183 (11): 7602–7610.

View articletitled, CD39<sup>+</sup>Foxp3<sup>+</sup> Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway

A. Chaudhry; D. A. Verghese; S. R. Das; S. Jameel; A. George; V. Bal; S. Mayor; S. Rath

J Immunol (2009) 183 (11): 7611.

View articletitled, HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway

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Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

N. Tatsis; M. O. Lasaro; S.-W. Lin; Z. Q. Xiang; D. Zhou; L. DiMenna; H. Li; A. Bian; S. Abdulla; Y. Li; W. Giles-Davis; J. Engram; S. J. Ratcliffe; G. Silvestri; H. C. Ertl; M. R. Betts

J Immunol (2009) 183 (11): 7611.

View articletitled, Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

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Cover Image

Cover Image

On the cover: A single linear polypeptide comprising a pentameric (green) and trimeric (blue) coiled-coil domain self-assembles into an icosahedral nanoparticle composed of 60 peptide chains. Peptide B cell epitopes (red) cloned onto the end of the gene are displayed on the surface in a highly ordered repetitive array that is extremely immunogenic. Kaba, S. A., C. Brando, Q. Guo, C. Mittelholzer, S. Raman, D. Tropel, U. Aebi, P. Burkhard, and D. E. Lanar. 2009. A non-adjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria. J. Immunol 183: 7268–7277.
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