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Issues
15 December 2009
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
Comment on “Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF-κB-Dependent Cytokine Expression in Fibroblasts”
J Immunol (2009) 183 (12): 7619.
Response to Comment on “Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF-κB-Dependent Cytokine Expression in Fibroblasts”
J Immunol (2009) 183 (12): 7620–7621.
BRIEF REVIEWS
Inflammasome-Associated Nucleotide-Binding Domain, Leucine-Rich Repeat Proteins and Inflammatory Diseases1
J Immunol (2009) 183 (12): 7623–7629.
CUTTING EDGE
Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice1
Jeong Kim; Katharina Lahl; Shohei Hori; Christoph Loddenkemper; Ashutosh Chaudhry; Paul deRoos; Alexander Rudensky; Tim Sparwasser
J Immunol (2009) 183 (12): 7631–7634.
Cutting Edge: Normal Regional Lymph Node Enrichment of Antigen-Specific Regulatory T Cells with Autoimmune Disease-Suppressive Capacity1
J Immunol (2009) 183 (12): 7635–7638.
Cutting Edge: Inhibitory Effects of CD4 and CD8 on T Cell Activation Induced by High-Affinity Noncognate Ligands1
J Immunol (2009) 183 (12): 7639–7643.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2−/−IL-2Rγc−/− Mice without Affecting Peripheral T Cell Homeostasis1
Anja U. van Lent; Wendy Dontje; Maho Nagasawa; Rachida Siamari; Arjen Q. Bakker; Stephan M. Pouw; Kelly A. Maijoor; Kees Weijer; Jan J. Cornelissen; Bianca Blom; James P. Di Santo; Hergen Spits; Nicolas Legrand
J Immunol (2009) 183 (12): 7645–7655.
Activated CD8+ T-Effector/Memory Cells Eliminate CD4+ CD25+ Foxp3+ T-Suppressor Cells from Tumors via FasL Mediated Apoptosis1
J Immunol (2009) 183 (12): 7656–7660.
B7-1/2 (CD80/CD86) Direct Signaling to B Cells Enhances IgG Secretion1
J Immunol (2009) 183 (12): 7661–7671.
Tracking the Total CD8 T Cell Response to Infection Reveals Substantial Discordance in Magnitude and Kinetics between Inbred and Outbred Hosts1
J Immunol (2009) 183 (12): 7672–7681.
Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes1
J Immunol (2009) 183 (12): 7682–7691.
The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling1
Sandrine Crabé; Angélique Guay-Giroux; Aurélie Jeanne Tormo; Dorothée Duluc; Rami Lissilaa; Florence Guilhot; Ulrick Mavoungou-Bigouagou; Fouad Lefouili; Isabelle Cognet; Walter Ferlin; Greg Elson; Pascale Jeannin; Jean-François Gauchat
J Immunol (2009) 183 (12): 7692–7702.
Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production1
Caroline R. Boyd; Selinda J. Orr; Shaun Spence; James F. Burrows; Joanne Elliott; Helen P. Carroll; Kiva Brennan; Joan Ní Gabhann; Wilson A. Coulter; James A. Johnston; Caroline A. Jefferies
J Immunol (2009) 183 (12): 7703–7709.
IFN-γ Expressed by T Cells Regulates the Persistence of Antigen Presentation by Limiting the Survival of Dendritic Cells1
J Immunol (2009) 183 (12): 7710–7718.
Human Activated T Lymphocytes Modulate IDO Expression in Tumors through Th1/Th2 Balance1
Jessica Godin-Ethier; Sandy Pelletier; Laïla-Aïcha Hanafi; Philippe O. Gannon; Marie-Andrée Forget; Jean-Pierre Routy; Mohamed-Rachid Boulassel; Urszula Krzemien; Simon Tanguay; Jean-Baptiste Lattouf; Nathalie Arbour; Réjean Lapointe
J Immunol (2009) 183 (12): 7752–7760.
Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens1
J Immunol (2009) 183 (12): 7761–7767.
Asynchronous RAG-1 Expression during B Lymphopoiesis1
Robert S. Welner; Brandt L. Esplin; Karla P. Garrett; Rosana Pelayo; Hervé Luche; Hans Jörg Fehling; Paul W. Kincade
J Immunol (2009) 183 (12): 7768–7777.
Brain-Derived Neurotrophic Factor Induces Sustained Elevation of Intracellular Ca2+ in Rodent Microglia1
Yoshito Mizoguchi; Akira Monji; Takahiro Kato; Yoshihiro Seki; Leo Gotoh; Hideki Horikawa; Satoshi O. Suzuki; Toru Iwaki; Miyuki Yonaha; Sadayuki Hashioka; Shigenobu Kanba
J Immunol (2009) 183 (12): 7778–7786.
Activation, Immune Polarization, and Graft-versus-Leukemia Activity of Donor T Cells Are Regulated by Specific Subsets of Donor Bone Marrow Antigen-Presenting Cells in Allogeneic Hemopoietic Stem Cell Transplantation1
Jian-Ming Li; Lauren T. Southerland; Ying Lu; Kataryna A. Darlak; Cynthia R. Giver; Douglas W. McMillin; Wayne A. C. Harris; David L. Jaye; Edmund K. Waller
J Immunol (2009) 183 (12): 7799–7809.
An Innate Response to Allogeneic Nonself Mediated by Monocytes1
J Immunol (2009) 183 (12): 7810–7816.
The Runx3 Transcription Factor Augments Th1 and Down-Modulates Th2 Phenotypes by Interacting with and Attenuating GATA31
Kazuyoshi Kohu; Hidetaka Ohmori; Won Fen Wong; Daisuke Onda; Takeshi Wakoh; Shunsuke Kon; Masakatsu Yamashita; Toshinori Nakayama; Masato Kubo; Masanobu Satake
J Immunol (2009) 183 (12): 7817–7824.
Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption1
Keiichi Koizumi; Yurika Saitoh; Takayuki Minami; Nobuhiro Takeno; Koichi Tsuneyama; Tatsuro Miyahara; Takashi Nakayama; Hiroaki Sakurai; Yasuo Takano; Miyuki Nishimura; Toshio Imai; Osamu Yoshie; Ikuo Saiki
J Immunol (2009) 183 (12): 7825–7831.
TLR2 Engagement on Dendritic Cells Promotes High Frequency Effector and Memory CD4 T Cell Responses1
J Immunol (2009) 183 (12): 7832–7841.
Soluble B and T Lymphocyte Attenuator Possesses Antitumor Effects and Facilitates Heat Shock Protein 70 Vaccine-Triggered Antitumor Immunity against a Murine TC-1 Cervical Cancer Model In Vivo1
Lingfei Han; Wei Wang; Yong Fang; Zuohua Feng; Shujie Liao; Wei Li; Yan Li; Chunxiao Li; Mayinuer Maitituoheti; Hong Dong; Zhiwen Lai; Qinglei Gao; Ling Xi; Mingfu Wu; Daowen Wang; Jianfeng Zhou; Li Meng; Shixuan Wang; Ding Ma
J Immunol (2009) 183 (12): 7842–7850.
Sublingual Immunization with Nonreplicating Antigens Induces Antibody-Forming Cells and Cytotoxic T Cells in the Female Genital Tract Mucosa and Protects against Genital Papillomavirus Infection1
Nicolas Çuburu; Mi-Na Kweon; Catherine Hervouet; Hye-Ran Cha; Yuk-Ying S. Pang; Jan Holmgren; Konrad Stadler; John T. Schiller; Fabienne Anjuère; Cecil Czerkinsky
J Immunol (2009) 183 (12): 7851–7859.
IL-13Rα2 Membrane and Soluble Isoforms Differ in Humans and Mice1
Weiguo Chen; Umasundari Sivaprasad; Yasuhiro Tabata; Aaron M. Gibson; Matthew T. Stier; Fred D. Finkelman; Gurjit K. Khurana Hershey
J Immunol (2009) 183 (12): 7870–7876.
Neuronal IκB Kinase β Protects Mice from Autoimmune Encephalomyelitis by Mediating Neuroprotective and Immunosuppressive Effects in the Central Nervous System1
Mary Emmanouil; Era Taoufik; Vivian Tseveleki; Sotiris-Spyros Vamvakas; Theodore Tselios; Michael Karin; Hans Lassmann; Lesley Probert
J Immunol (2009) 183 (12): 7877–7889.
Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages1
Tatsukuni Ohno; Keisuke Oboki; Naoki Kajiwara; Eiichi Morii; Katsuyuki Aozasa; Richard A. Flavell; Ko Okumura; Hirohisa Saito; Susumu Nakae
J Immunol (2009) 183 (12): 7890–7897.
Dual Control of Antitumor CD8 T Cells through the Programmed Death-1/Programmed Death-Ligand 1 Pathway and Immunosuppressive CD4 T Cells: Regulation and Counterregulation1
Andrew J. Currie; Amy Prosser; Alison McDonnell; Amanda L. Cleaver; Bruce W. S. Robinson; Gordon J. Freeman; Robbert G. van der Most
J Immunol (2009) 183 (12): 7898–7908.
Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction1
J Immunol (2009) 183 (12): 7909–7918.
The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response1
Rama S. Akondy; Nathan D. Monson; Joseph D. Miller; Srilatha Edupuganti; Dirk Teuwen; Hong Wu; Farah Quyyumi; Seema Garg; John D. Altman; Carlos Del Rio; Harry L. Keyserling; Alexander Ploss; Charles M. Rice; Walter A. Orenstein; Mark J. Mulligan; Rafi Ahmed
J Immunol (2009) 183 (12): 7919–7930.
RasGRP1 Is Required for Human NK Cell Function1
Suk Hyung Lee; Sohyun Yun; Jiwon Lee; Mi Jeong Kim; Zheng-Hao Piao; Mira Jeong; Jin Woong Chung; Tae-Don Kim; Suk Ran Yoon; Philip D. Greenberg; Inpyo Choi
J Immunol (2009) 183 (12): 7931–7938.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
IMMUNOGENETICS
The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease1
Nengming Xiao; Celine Eidenschenk; Philippe Krebs; Katharina Brandl; Amanda L. Blasius; Yu Xia; Kevin Khovananth; Nora G. Smart; Bruce Beutler
J Immunol (2009) 183 (12): 7975–7983.
HOST DEFENSE
Enhanced Susceptibility to Leishmania Infection in Resistant Mice in the Absence of Immediate Early Response Gene X-11
J Immunol (2009) 183 (12): 7994–8003.
In a Murine Tuberculosis Model, the Absence of Homeostatic Chemokines Delays Granuloma Formation and Protective Immunity1
Shabaana A. Khader; Javier Rangel-Moreno; Jeffrey J. Fountain; Cynthia A. Martino; William W. Reiley; John E. Pearl; Gary M. Winslow; David L. Woodland; Troy D. Randall; Andrea M. Cooper
J Immunol (2009) 183 (12): 8004–8014.
The Heavy Chain Variable Segment Gene Repertoire in Chronic Chagas′ Heart Disease1
Vanina Grippo; Evelyn Mahler; Fernando E. Elias; Ana Cauerhff; Karina A. Gómez; Maria C. Tentori; Aurora Ruiz; Carlos A. Vigliano; Ruben P. Laguens; Claudia Berek; Mariano J. Levin
J Immunol (2009) 183 (12): 8015–8025.
IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes1
J Immunol (2009) 183 (12): 8026–8034.
Distinct Antiviral Roles for Human 2′,5′-Oligoadenylate Synthetase Family Members against Dengue Virus Infection1
J Immunol (2009) 183 (12): 8035–8043.
Accumulation of CD11b+ Lung Dendritic Cells in Response to Fungal Infection Results from the CCR2-Mediated Recruitment and Differentiation of Ly-6Chigh Monocytes12
John J. Osterholzer; Gwo-Hsiao Chen; Michal A. Olszewski; Jeffrey L. Curtis; Gary B. Huffnagle; Galen B. Toews
J Immunol (2009) 183 (12): 8044–8053.
β-Defensins 2 and 3 Together Promote Resistance to Pseudomonas aeruginosa Keratitis1
J Immunol (2009) 183 (12): 8054–8060.
Infection with Arginase-Deficient Leishmania major Reveals a Parasite Number-Dependent and Cytokine-Independent Regulation of Host Cellular Arginase Activity and Disease Pathogenesis1
Helen M. Muleme; Rosa M. Reguera; Alicia Berard; Richard Azinwi; Ping Jia; Ifeoma B. Okwor; Stephen Beverley; Jude E. Uzonna
J Immunol (2009) 183 (12): 8068–8076.
Neutrophils and Macrophages Cooperate in Host Resistance against Leishmania braziliensis Infection1
Fernanda O. Novais; Rômulo C. Santiago; André Báfica; Ricardo Khouri; Lilian Afonso; Valéria M. Borges; Cláudia Brodskyn; Manoel Barral-Netto; Aldina Barral; Camila I. de Oliveira
J Immunol (2009) 183 (12): 8088–8098.
Helicobacter pylori Induces MAPK Phosphorylation and AP-1 Activation via a NOD1-Dependent Mechanism1
J Immunol (2009) 183 (12): 8099–8109.
INFLAMMATION
Signaling Crosstalk during Sequential TLR4 and TLR9 Activation Amplifies the Inflammatory Response of Mouse Macrophages1
J Immunol (2009) 183 (12): 8110–8118.
Cell Surface Externalization of Annexin A1 as a Failsafe Mechanism Preventing Inflammatory Responses during Secondary Necrosis1
Karin E. Blume; Szabolcs Soeroes; Michaela Waibel; Hildegard Keppeler; Sebastian Wesselborg; Martin Herrmann; Klaus Schulze-Osthoff; Kirsten Lauber
J Immunol (2009) 183 (12): 8138–8147.
Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation1
Sinéad Weldon; Paul McNally; Noel G. McElvaney; J. Stuart Elborn; Danny F. McAuley; Julien Wartelle; Abderrazzaq Belaaouaj; Rodney L. Levine; Clifford C. Taggart
J Immunol (2009) 183 (12): 8148–8156.
DcR3 Protects Islet β Cells from Apoptosis through Modulating Adcyap1 and Bank1 Expression1
J Immunol (2009) 183 (12): 8157–8166.
Inhibition of IL-17A Attenuates Atherosclerotic Lesion Development in ApoE-Deficient Mice1
Christian Erbel; Lili Chen; Florian Bea; Susanne Wangler; Sultan Celik; Felix Lasitschka; Ying Wang; Dittmar Böckler; Hugo A. Katus; Thomas J. Dengler
J Immunol (2009) 183 (12): 8167–8175.
Expression of Soluble Vascular Endothelial Growth Factor Receptor-1 in Human Monocyte-Derived Mature Dendritic Cells Contributes to Their Antiangiogenic Property1
Masatoshi Kishuku; Yasuhiko Nishioka; Shinji Abe; Jun Kishi; Hirokazu Ogino; Yoshinori Aono; Momoyo Azuma; Katsuhiro Kinoshita; Batmungh Rentsenhand; Hideki Makino; Priya Ranjan; Kazuo Minakuchi; Saburo Sone
J Immunol (2009) 183 (12): 8176–8185.
CCR7 Modulates Pulmonary and Lymph Node Inflammatory Responses in Cigarette Smoke-Exposed Mice1
J Immunol (2009) 183 (12): 8186–8194.
IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema1
Isabelle Couillin; Virginie Vasseur; Sabine Charron; Pamela Gasse; Marie Tavernier; Julien Guillet; Vincent Lagente; Lizette Fick; Muazzam Jacobs; Fernando Rodrigues Coelho; René Moser; Bernhard Ryffel
J Immunol (2009) 183 (12): 8195–8202.
CD69 Controls the Pathogenesis of Allergic Airway Inflammation1
Takako Miki-Hosokawa; Akihiro Hasegawa; Chiaki Iwamura; Kenta Shinoda; Soichi Tofukuji; Yukiko Watanabe; Hiroyuki Hosokawa; Shinichiro Motohashi; Kahoko Hashimoto; Mutsunori Shirai; Masakatsu Yamashita; Toshinori Nakayama
J Immunol (2009) 183 (12): 8203–8215.
Dynamics of the Interaction of Human IgG Subtype Immune Complexes with Cells Expressing R and H Allelic Forms of a Low-Affinity Fcγ Receptor CD32A1
Rangaiah Shashidharamurthy; Fang Zhang; Aaron Amano; Aparna Kamat; Ravichandran Panchanathan; Daniel Ezekwudo; Cheng Zhu; Periasamy Selvaraj
J Immunol (2009) 183 (12): 8216–8224.
CLINICAL IMMUNOLOGY
Autoantibodies against C1q in Systemic Lupus Erythematosus Are Antigen-Driven1
J Immunol (2009) 183 (12): 8225–8231.
In Vivo Induction of Type 1-Like Regulatory T Cells Using Genetically Modified B Cells Confers Long-Term IL-10-Dependent Antigen-Specific Unresponsiveness1
Roxana Roohi Ahangarani; Wim Janssens; Luc VanderElst; Vincent Carlier; Thierry VandenDriessche; Marinee Chuah; Birgit Weynand; Jeroen A. J. Vanoirbeek; Marc Jacquemin; Jean-Marie Saint-Remy
J Immunol (2009) 183 (12): 8232–8243.
ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis1
Karnail Singh; Pratima Deshpande; Sergey Pryshchep; Inés Colmegna; Vladimir Liarski; Cornelia M. Weyand; Jörg J. Goronzy
J Immunol (2009) 183 (12): 8258–8267.
A Dual Action of Rheumatoid Arthritis Synovial Fibroblast IL-15 Expression on the Equilibrium between CD4+CD25+ Regulatory T Cells and CD4+CD25− Responder T Cells1
Marta Benito-Miguel; Yolanda García-Carmona; Alejandro Balsa; Carlos Pérez de Ayala; Tatiana Cobo-Ibáñez; Emilio Martín-Mola; María-Eugenia Miranda-Carús
J Immunol (2009) 183 (12): 8268–8279.
Allele *1 of HS1.2 Enhancer Associates with Selective IgA Deficiency and IgM Concentration1
Vincenzo Giambra; Rossella Cianci; Serena Lolli; Claudia Mattioli; Giacomo Tampella; Marco Cattalini; Sebnem S. Kilic; Franco Pandolfi; Alessandro Plebani; Domenico Frezza
J Immunol (2009) 183 (12): 8280–8285.
CORRECTIONS
Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII
M. Miksa; R. Wu; W. Dong; H. Komura; D. Amin; Y. Ji; Z. Wang; H. Wang; T. S. Ravikumar; K. J. Tracey; P. Wang
J Immunol (2009) 183 (12): 8295.
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Cover Image
Cover Image
On the cover: Laser scanning confocal micrograph of one day post infection BALB/c mouse cornea showing epithelial and stromal staining for murine β-defensin 4. Wu, M., S. A. McClellan, R. P. Barrett, Y. Zhang, and L. D. Hazlett. 2009. β-Defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis. J. Immunol 183: 8054–8060.
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