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Issues
1 September 2009
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
PILLARS OF IMMUNOLOGY
Where the Confusion Began: Cloning the First Chemokine Receptors
J Immunol (2009) 183 (5): 2893–2894.
BRIEF REVIEWS
CUTTING EDGE
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
C3 Promotes Expansion of CD8+ and CD4+ T Cells in a Listeria monocytogenes Infection1
J Immunol (2009) 183 (5): 2921–2931.
Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells1
J Immunol (2009) 183 (5): 2946–2956.
High Frequencies of Functionally Competent Circulating Tax-Specific CD8+ T Cells in Human T Lymphotropic Virus Type 2 Infection
André L. A. Oliveira; Hitoshi Hayakawa; Doris Schor; Ana Claudia C. B. Leite; Otávio M. Espíndola; Allison Waters; Jonathan Dean; Derek G. Doherty; Abelardo Q.-C. Araújo; William W. Hall
J Immunol (2009) 183 (5): 2957–2965.
TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program1
Sonia Chamorro; Juan J. García-Vallejo; Wendy W. J. Unger; Rosette J. Fernandes; Sven C. M. Bruijns; Sandra Laban; Bart O. Roep; Bert A. 't Hart; Yvette van Kooyk
J Immunol (2009) 183 (5): 2984–2994.
The Gli3 Transcription Factor Expressed in the Thymus Stroma Controls Thymocyte Negative Selection Via Hedgehog-Dependent and -Independent Mechanisms1
Ariadne L. Hager-Theodorides; Anna L. Furmanski; Susan E. Ross; Susan V. Outram; Nicola J. Rowbotham; Tessa Crompton
J Immunol (2009) 183 (5): 3023–3032.
Secretion and Biological Activity of Short Signal Peptide IL-15 Is Chaperoned by IL-15 Receptor Alpha In Vivo1
Cristina Bergamaschi; Rashmi Jalah; Viraj Kulkarni; Margherita Rosati; Gen-Mu Zhang; Candido Alicea; Andrei S. Zolotukhin; Barbara K. Felber; George N. Pavlakis
J Immunol (2009) 183 (5): 3064–3072.
The C-Type Lectin-Like Receptor CLEC-1, Expressed by Myeloid Cells and Endothelial Cells, Is Up-Regulated by Immunoregulatory Mediators and Moderates T Cell Activation1
Pamela Thebault; Natacha Lhermite; Gaëlle Tilly; Laëtitia Le Texier; Thibaut Quillard; Michele Heslan; Ignacio Anegon; Jean-Paul Soulillou; Sophie Brouard; Beatrice Charreau; Maria-Cristina Cuturi; Elise Chiffoleau
J Immunol (2009) 183 (5): 3099–3108.
Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes1
Kei Yasuda; Christophe Richez; Melissa B. Uccellini; Rocco J. Richards; Ramon G. Bonegio; Shizuo Akira; Marc Monestier; Ronald B. Corley; Gregory A. Viglianti; Ann Marshak-Rothstein; Ian R. Rifkin
J Immunol (2009) 183 (5): 3109–3117.
Self-Peptides Prolong Survival in Murine Autoimmunity via Reduced IL-2/IL-7-Mediated STAT5 Signaling, CD8 Coreceptor, and Vα2 Down-Regulation1
J Immunol (2009) 183 (5): 3130–3138.
Modulation of Single-Cell IgG Secretion Frequency and Rates in Human Memory B Cells by CpG DNA, CD40L, IL-21, and Cell Division1
Alicia D. Henn; Jonathan Rebhahn; Miguel A. Brown; Alison J. Murphy; Mircea N. Coca; Ollivier Hyrien; Tina Pellegrin; Tim Mosmann; Martin S. Zand
J Immunol (2009) 183 (5): 3177–3187.
Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands
Brian A. Zabel; Yu Wang; Susanna Lewén; Robert D. Berahovich; Mark E. T. Penfold; Penglie Zhang; Jay Powers; Bretton C. Summers; Zhenhua Miao; Bin Zhao; Ali Jalili; Anna Janowska-Wieczorek; Juan C. Jaen; Thomas J. Schall
J Immunol (2009) 183 (5): 3204–3211.
Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-β In Vivo1
Stefan Lienenklaus; Marius Cornitescu; Natalia Ziętara; Marcin Łyszkiewicz; Nelson Gekara; Jadwiga Jabłońska; Frank Edenhofer; Klaus Rajewsky; Dunja Bruder; Martin Hafner; Peter Staeheli; Siegfried Weiss
J Immunol (2009) 183 (5): 3229–3236.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
The Binding of Antigenic Peptides to HLA-DR Is Influenced by Interactions between Pocket 6 and Pocket 91
J Immunol (2009) 183 (5): 3249–3258.
IMMUNOGENETICS
Ornithorhynchus anatinus (Platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Nonmammalian Tetrapods12
Yaofeng Zhao; Huiting Cui; Camilla M. Whittington; Zhiguo Wei; Xiaofeng Zhang; Ziding Zhang; Li Yu; Liming Ren; Xiaoxiang Hu; Yaping Zhang; Lars Hellman; Katherine Belov; Ning Li; Lennart Hammarström
J Immunol (2009) 183 (5): 3285–3293.
HOST DEFENSE
Sequential, Ordered Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 Domains1
Gerald K. K. Cham; Louise Turner; John Lusingu; Lasse Vestergaard; Bruno P. Mmbando; Jonathan D. Kurtis; Anja T. R. Jensen; Ali Salanti; Thomas Lavstsen; Thor G. Theander
J Immunol (2009) 183 (5): 3356–3363.
Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization1
Pia Dosenovic; Bimal Chakrabarti; Martina Soldemo; Iyadh Douagi; Mattias N. E. Forsell; Yuxing Li; Adhuna Phogat; Staffan Paulie; James Hoxie; Richard T. Wyatt; Gunilla B. Karlsson Hedestam
J Immunol (2009) 183 (5): 3373–3382.
INFLAMMATION
12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis
Gerhard Krönke; Julia Katzenbeisser; Stefan Uderhardt; Mario M. Zaiss; Carina Scholtysek; Gernot Schabbauer; Alexander Zarbock; Marije I. Koenders; Roland Axmann; Jochen Zwerina; Hans W. Baenckler; Wim van den Berg; Reinhard E. Voll; Hartmut Kühn; Leo A. B. Joosten; Georg Schett
J Immunol (2009) 183 (5): 3383–3389.
GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway1
J Immunol (2009) 183 (5): 3390–3399.
Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function1
Márton Megyeri; Veronika Makó; László Beinrohr; Zoltán Doleschall; Zoltán Prohászka; László Cervenak; Péter Závodszky; Péter Gál
J Immunol (2009) 183 (5): 3409–3416.
Identification of Human Cathepsin G As a Functional Target of Boswellic Acids from the Anti-Inflammatory Remedy Frankincense1
Lars Tausch; Arne Henkel; Ulf Siemoneit; Daniel Poeckel; Nicole Kather; Lutz Franke; Bettina Hofmann; Gisbert Schneider; Carlo Angioni; Gerd Geisslinger; Carsten Skarke; Wolfgang Holtmeier; Tobias Beckhaus; Michael Karas; Johann Jauch; Oliver Werz
J Immunol (2009) 183 (5): 3433–3442.
Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease
Antonio Di Sabatino; Laura Rovedatti; Rejbinder Kaur; Jonathan P. Spencer; Jon T. Brown; Valerie D. Morisset; Paolo Biancheri; Nicholas A. B. Leakey; Jonathan I. Wilde; Laurie Scott; Gino R. Corazza; Kevin Lee; Neel Sengupta; Charles H. Knowles; Martin J. Gunthorpe; Peter G. McLean; Thomas T. MacDonald; Laurens Kruidenier
J Immunol (2009) 183 (5): 3454–3462.
Lymphocytes in the Development of Lung Inflammation: A Role for Regulatory CD4+ T Cells in Indirect Pulmonary Lung Injury1
J Immunol (2009) 183 (5): 3472–3480.
CLINICAL IMMUNOLOGY
Stimulatory and Inhibitory Killer Ig-Like Receptor Molecules Are Expressed and Functional on Lupus T Cells1
Dhiman Basu; Ying Liu; Ailing Wu; Sushma Yarlagadda; Gabriela J. Gorelik; Mariana J. Kaplan; Anura Hewagama; Robert C. Hinderer; Faith M. Strickland; Bruce C. Richardson
J Immunol (2009) 183 (5): 3481–3487.
γ-Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways1
J Immunol (2009) 183 (5): 3488–3495.
Mannose-Binding Lectin (MBL) Substitution: Recovery of Opsonic Function In Vivo Lags behind MBL Serum Levels1
Nannette Brouwer; Florine N. J. Frakking; Marianne D. van de Wetering; Michel van Houdt; Margreet Hart; Ilona Kleine Budde; Paul F. W. Strengers; Inga Laursen; Gunnar Houen; Dirk Roos; Jens C. Jensenius; Huib N. Caron; Koert M. Dolman; Taco W. Kuijpers
J Immunol (2009) 183 (5): 3496–3504.
CORRECTIONS
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Cover Image
Cover Image
![issue cover]()
On the cover: Modeled pocket 6 of HLA-DRB1*0901 (shown with p6Lys in foreground), uniquely accommodates a wide range of residues (acidic, aliphatic, polar, and basic), due to the arrangement of three acidic and two basic residues (shown in stick form). β9Lys swings into this pocket although normally found pointing into neighboring pocket 9. James, E. A., A. K. Moustakas, J. Bui, R. Nouv, G. K. Papadopoulos, and W. W. Kwok. 2009. The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9. J. Immunol. 183: 3249–3258.
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