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J Immunol (2009) 183 (5): 2889–2890.

View articletitled, IN THIS ISSUE

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LETTERS TO THE EDITOR

Comment on “Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER^T2”

Anja Uhmann; Kai Dittmann; Jürgen Wienands; Heidi Hahn

J Immunol (2009) 183 (5): 2891.

View articletitled, Comment on “Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER<sup>T2</sup>”

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Response to Comment on “Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER^T2”

Motoko Yanagita; Atsuko Higashi; Tomokatsu Ikawa; Masamichi Muramatsu; Aris N. Economides; Hiroshi Kawamoto

J Immunol (2009) 183 (5): 2891–2892.

View articletitled, Response to Comment on “Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER<sup>T2</sup>”

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PILLARS OF IMMUNOLOGY

Where the Confusion Began: Cloning the First Chemokine Receptors

Barrett J. Rollins

J Immunol (2009) 183 (5): 2893–2894.

View articletitled, Where the Confusion Began: Cloning the First Chemokine Receptors

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Pillars Article: Structure and functional expression of a human interleukin-8 receptor. Science. 1991. 253: 1278–1280.

William E. Holmes; James Lee; Wun-Jing Kuang; Glenn C. Rice; William I. Wood

J Immunol (2009) 183 (5): 2895–2897.

View articletitled, Pillars Article: Structure and functional expression of a human interleukin-8 receptor. <em>Science</em>. 1991. 253: 1278–1280.

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Pillars Article: Cloning of complementary DNA encoding a functional human interleukin-8 receptor. Science. 1991. 253: 1280–1283.

Phillip M. Murphy; H. Lee Tiffany

J Immunol (2009) 183 (5): 2898–2901.

View articletitled, Pillars Article: Cloning of complementary DNA encoding a functional human interleukin-8 receptor. <em>Science</em>. 1991. 253: 1280–1283.

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BRIEF REVIEWS

CD4-CD8 Lineage Differentiation: Thpok-ing into the Nucleus ¹

Lie Wang; Rémy Bosselut

J Immunol (2009) 183 (5): 2903–2910.

View articletitled, CD4-CD8 Lineage Differentiation: Thpok-ing into the Nucleus<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: IL-15-Independent NK Cell Response to Mouse Cytomegalovirus Infection ¹

Joseph C. Sun; Averil Ma; Lewis L. Lanier

J Immunol (2009) 183 (5): 2911–2914.

View articletitled, Cutting Edge: IL-15-Independent NK Cell Response to Mouse Cytomegalovirus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Type I Interferon (IFNα) Acts Directly on Human Memory CD4⁺ T Cells Altering Their Response to Antigen ¹

Kathleen M. E. Gallagher; Sarah Lauder; Ian W. Rees; Awen M. Gallimore; Andrew J. Godkin

J Immunol (2009) 183 (5): 2915–2920.

View articletitled, Type I Interferon (IFNα) Acts Directly on Human Memory CD4<sup>+</sup> T Cells Altering Their Response to Antigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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C3 Promotes Expansion of CD8⁺ and CD4⁺ T Cells in a Listeria monocytogenes Infection ¹

Yumi Nakayama; Shin-Il Kim; Eui Ho Kim; John D. Lambris; Matyas Sandor; M. Suresh

J Immunol (2009) 183 (5): 2921–2931.

View articletitled, C3 Promotes Expansion of CD8<sup>+</sup> and CD4<sup>+</sup> T Cells in a <em>Listeria monocytogenes</em> Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN-γ, as Secreted during an Alloresponse, Induces Differentiation of Monocytes into Tolerogenic Dendritic Cells, Resulting in FoxP3⁺ Regulatory T Cell Promotion ¹

Assia Eljaafari; Yin-Ping Li; Pierre Miossec

J Immunol (2009) 183 (5): 2932–2945.

View articletitled, IFN-γ, as Secreted during an Alloresponse, Induces Differentiation of Monocytes into Tolerogenic Dendritic Cells, Resulting in FoxP3<sup>+</sup> Regulatory T Cell Promotion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells ¹

Yakup Tanriver; Alfonso Martín-Fontecha; Kulachelvy Ratnasothy; Giovanna Lombardi; Robert Lechler

J Immunol (2009) 183 (5): 2946–2956.

View articletitled, Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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High Frequencies of Functionally Competent Circulating Tax-Specific CD8⁺ T Cells in Human T Lymphotropic Virus Type 2 Infection

André L. A. Oliveira; Hitoshi Hayakawa; Doris Schor; Ana Claudia C. B. Leite; Otávio M. Espíndola; Allison Waters; Jonathan Dean; Derek G. Doherty; Abelardo Q.-C. Araújo; William W. Hall

J Immunol (2009) 183 (5): 2957–2965.

View articletitled, High Frequencies of Functionally Competent Circulating Tax-Specific CD8<sup>+</sup> T Cells in Human T Lymphotropic Virus Type 2 Infection

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Roles of the TRAF2/3 Binding Site in Differential B Cell Signaling by CD40 and Its Viral Oncogenic Mimic, LMP1 ¹

John P. Graham; Carissa R. Moore; Gail A. Bishop

J Immunol (2009) 183 (5): 2966–2973.

View articletitled, Roles of the TRAF2/3 Binding Site in Differential B Cell Signaling by CD40 and Its Viral Oncogenic Mimic, LMP1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Antigen Receptor Signals Rescue B Cells from TLR Tolerance ¹

Jayakumar S. Poovassery; Tony J. Vanden Bush; Gail A. Bishop

J Immunol (2009) 183 (5): 2974–2983.

View articletitled, Antigen Receptor Signals Rescue B Cells from TLR Tolerance<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program ¹

Sonia Chamorro; Juan J. García-Vallejo; Wendy W. J. Unger; Rosette J. Fernandes; Sven C. M. Bruijns; Sandra Laban; Bart O. Roep; Bert A. 't Hart; Yvette van Kooyk

J Immunol (2009) 183 (5): 2984–2994.

View articletitled, TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Jagged1 on Dendritic Cells and Notch on CD4⁺ T Cells Initiate Lung Allergic Responsiveness by Inducing IL-4 Production ¹^²

Masakazu Okamoto; Hiroyuki Matsuda; Anthony Joetham; Joseph J. Lucas; Joanne Domenico; Koji Yasutomo; Katsuyuki Takeda; Erwin W. Gelfand

J Immunol (2009) 183 (5): 2995–3003.

View articletitled, Jagged1 on Dendritic Cells and Notch on CD4<sup>+</sup> T Cells Initiate Lung Allergic Responsiveness by Inducing IL-4 Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Survival and Migration of Human Dendritic Cells Are Regulated by an IFN-α-Inducible Axl/Gas6 Pathway ¹

Sara Scutera; Tiziana Fraone; Tiziana Musso; Paola Cappello; Silvia Rossi; Daniele Pierobon; Zane Orinska; Ralf Paus; Silvia Bulfone-Paus; Mirella Giovarelli

J Immunol (2009) 183 (5): 3004–3013.

View articletitled, Survival and Migration of Human Dendritic Cells Are Regulated by an IFN-α-Inducible Axl/Gas6 Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Mast Cells Down-Regulate CD4⁺CD25⁺ T Regulatory Cell Suppressor Function via Histamine H1 Receptor Interaction ¹

Nicholas A. Forward; Suzanne J. Furlong; Yongjun Yang; Tong-Jun Lin; David W. Hoskin

J Immunol (2009) 183 (5): 3014–3022.

View articletitled, Mast Cells Down-Regulate CD4<sup>+</sup>CD25<sup>+</sup> T Regulatory Cell Suppressor Function via Histamine H1 Receptor Interaction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Gli3 Transcription Factor Expressed in the Thymus Stroma Controls Thymocyte Negative Selection Via Hedgehog-Dependent and -Independent Mechanisms ¹

Ariadne L. Hager-Theodorides; Anna L. Furmanski; Susan E. Ross; Susan V. Outram; Nicola J. Rowbotham; Tessa Crompton

J Immunol (2009) 183 (5): 3023–3032.

View articletitled, The Gli3 Transcription Factor Expressed in the Thymus Stroma Controls Thymocyte Negative Selection Via Hedgehog-Dependent and -Independent Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Basophils Can Directly Present or Cross-Present Antigen to CD8 Lymphocytes and Alter CD8 T Cell Differentiation into IL-10-Producing Phenotypes ¹

Sohee Kim; Tao Shen; Booki Min

J Immunol (2009) 183 (5): 3033–3039.

View articletitled, Basophils Can Directly Present or Cross-Present Antigen to CD8 Lymphocytes and Alter CD8 T Cell Differentiation into IL-10-Producing Phenotypes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Inhibition of Thymic Adipogenesis by Caloric Restriction Is Coupled with Reduction in Age-Related Thymic Involution ¹

Hyunwon Yang; Yun-Hee Youm; Vishwa Deep Dixit

J Immunol (2009) 183 (5): 3040–3052.

View articletitled, Inhibition of Thymic Adipogenesis by Caloric Restriction Is Coupled with Reduction in Age-Related Thymic Involution<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Crucial Contribution of Thymic Sirpα⁺ Conventional Dendritic Cells to Central Tolerance against Blood-Borne Antigens in a CCR2-Dependent Manner

Tomohisa Baba; Yasunari Nakamoto; Naofumi Mukaida

J Immunol (2009) 183 (5): 3053–3063.

View articletitled, Crucial Contribution of Thymic Sirpα<sup>+</sup> Conventional Dendritic Cells to Central Tolerance against Blood-Borne Antigens in a CCR2-Dependent Manner

Supplementary data

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Secretion and Biological Activity of Short Signal Peptide IL-15 Is Chaperoned by IL-15 Receptor Alpha In Vivo ¹

Cristina Bergamaschi; Rashmi Jalah; Viraj Kulkarni; Margherita Rosati; Gen-Mu Zhang; Candido Alicea; Andrei S. Zolotukhin; Barbara K. Felber; George N. Pavlakis

J Immunol (2009) 183 (5): 3064–3072.

View articletitled, Secretion and Biological Activity of Short Signal Peptide IL-15 Is Chaperoned by IL-15 Receptor Alpha In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism ¹

Andrea P. Martin; Tatjana Marinkovic; Claudia Canasto-Chibuque; Rauf Latif; Jay C. Unkeless; Terry F. Davies; Yousuke Takahama; Glaucia C. Furtado; Sergio A. Lira

J Immunol (2009) 183 (5): 3073–3080.

View articletitled, CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Compound A, a Plant Origin Ligand of Glucocorticoid Receptors, Increases Regulatory T Cells and M2 Macrophages to Attenuate Experimental Autoimmune Neuritis with Reduced Side Effects

Zhiren Zhang; Zhi-Yuan Zhang; Hermann J. Schluesener

J Immunol (2009) 183 (5): 3081–3091.

View articletitled, Compound A, a Plant Origin Ligand of Glucocorticoid Receptors, Increases Regulatory T Cells and M2 Macrophages to Attenuate Experimental Autoimmune Neuritis with Reduced Side Effects

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T Cell Activation by Heat Shock Protein 70 Vaccine Requires TLR Signaling and Scavenger Receptor Expressed by Endothelial Cells-1 ¹

Jianlin Gong; Bangmin Zhu; Ayesha Murshid; Hideki Adachi; Baizheng Song; Allegra Lee; Chunlei Liu; Stuart K. Calderwood

J Immunol (2009) 183 (5): 3092–3098.

View articletitled, T Cell Activation by Heat Shock Protein 70 Vaccine Requires TLR Signaling and Scavenger Receptor Expressed by Endothelial Cells-1<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The C-Type Lectin-Like Receptor CLEC-1, Expressed by Myeloid Cells and Endothelial Cells, Is Up-Regulated by Immunoregulatory Mediators and Moderates T Cell Activation ¹

Pamela Thebault; Natacha Lhermite; Gaëlle Tilly; Laëtitia Le Texier; Thibaut Quillard; Michele Heslan; Ignacio Anegon; Jean-Paul Soulillou; Sophie Brouard; Beatrice Charreau; Maria-Cristina Cuturi; Elise Chiffoleau

J Immunol (2009) 183 (5): 3099–3108.

View articletitled, The C-Type Lectin-Like Receptor CLEC-1, Expressed by Myeloid Cells and Endothelial Cells, Is Up-Regulated by Immunoregulatory Mediators and Moderates T Cell Activation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes ¹

Kei Yasuda; Christophe Richez; Melissa B. Uccellini; Rocco J. Richards; Ramon G. Bonegio; Shizuo Akira; Marc Monestier; Ronald B. Corley; Gregory A. Viglianti; Ann Marshak-Rothstein; Ian R. Rifkin

J Immunol (2009) 183 (5): 3109–3117.

View articletitled, Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TCR Repertoire and Foxp3 Expression Define Functionally Distinct Subsets of CD4⁺ Regulatory T Cells ¹

Michal Kuczma; Iwona Pawlikowska; Magdalena Kopij; Robert Podolsky; Grzegorz A. Rempala; Piotr Kraj

J Immunol (2009) 183 (5): 3118–3129.

View articletitled, TCR Repertoire and Foxp3 Expression Define Functionally Distinct Subsets of CD4<sup>+</sup> Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Self-Peptides Prolong Survival in Murine Autoimmunity via Reduced IL-2/IL-7-Mediated STAT5 Signaling, CD8 Coreceptor, and Vα2 Down-Regulation ¹

Jan Gutermuth; Kristine E. Nograles; Fumi Miyagawa; Emily Nelson; Young-Hun Cho; Stephen I. Katz

J Immunol (2009) 183 (5): 3130–3138.

View articletitled, Self-Peptides Prolong Survival in Murine Autoimmunity via Reduced IL-2/IL-7-Mediated STAT5 Signaling, CD8 Coreceptor, and Vα2 Down-Regulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts ¹

Tyani D. Chan; Dominique Gatto; Katherine Wood; Tahra Camidge; Antony Basten; Robert Brink

J Immunol (2009) 183 (5): 3139–3149.

View articletitled, Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Smallpox Inhibitor of Complement Enzymes (SPICE): Dissecting Functional Sites and Abrogating Activity ¹

M. Kathryn Liszewski; Marilyn K. Leung; Richard Hauhart; Celia J. Fang; Paula Bertram; John P. Atkinson

J Immunol (2009) 183 (5): 3150–3159.

View articletitled, Smallpox Inhibitor of Complement Enzymes (SPICE): Dissecting Functional Sites and Abrogating Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Role of IL-23/IL-17 Axis in Lupus Nephritis ¹

Zheng Zhang; Vasileios C. Kyttaris; George C. Tsokos

J Immunol (2009) 183 (5): 3160–3169.

View articletitled, The Role of IL-23/IL-17 Axis in Lupus Nephritis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells ¹

Wendy A. Goodman; Alan D. Levine; Jessica V. Massari; Hideaki Sugiyama; Thomas S. McCormick; Kevin D. Cooper

J Immunol (2009) 183 (5): 3170–3176.

View articletitled, IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Modulation of Single-Cell IgG Secretion Frequency and Rates in Human Memory B Cells by CpG DNA, CD40L, IL-21, and Cell Division ¹

Alicia D. Henn; Jonathan Rebhahn; Miguel A. Brown; Alison J. Murphy; Mircea N. Coca; Ollivier Hyrien; Tina Pellegrin; Tim Mosmann; Martin S. Zand

J Immunol (2009) 183 (5): 3177–3187.

View articletitled, Modulation of Single-Cell IgG Secretion Frequency and Rates in Human Memory B Cells by CpG DNA, CD40L, IL-21, and Cell Division<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells ¹

Jeff X. Zhou; Chang Hoon Lee; Chen Feng Qi; Hongsheng Wang; Zohreh Naghashfar; Sadia Abbasi; Herbert C. Morse, III

J Immunol (2009) 183 (5): 3188–3194.

View articletitled, IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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In Vivo Sensitized and In Vitro Activated B Cells Mediate Tumor Regression in Cancer Adoptive Immunotherapy ¹

Qiao Li; Seagal Teitz-Tennenbaum; Elizabeth J. Donald; Mu Li; Alfred E. Chang

J Immunol (2009) 183 (5): 3195–3203.

View articletitled, In Vivo Sensitized and In Vitro Activated B Cells Mediate Tumor Regression in Cancer Adoptive Immunotherapy<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands

Brian A. Zabel; Yu Wang; Susanna Lewén; Robert D. Berahovich; Mark E. T. Penfold; Penglie Zhang; Jay Powers; Bretton C. Summers; Zhenhua Miao; Bin Zhao; Ali Jalili; Anna Janowska-Wieczorek; Juan C. Jaen; Thomas J. Schall

J Immunol (2009) 183 (5): 3204–3211.

View articletitled, Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands

Supplementary data

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X-linked Foxp3 (Scurfy) Mutation Dominantly Inhibits Submandibular Gland Development and Inflammation Respectively through Adaptive and Innate Immune Mechanisms ¹

Rahul Sharma; Umesh S. Deshmukh; Lingjie Zheng; Shu Man Fu; Shyr-Te Ju

J Immunol (2009) 183 (5): 3212–3218.

View articletitled, X-linked Foxp3 (Scurfy) Mutation Dominantly Inhibits Submandibular Gland Development and Inflammation Respectively through Adaptive and Innate Immune Mechanisms<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tissue-Specific Homing and Expansion of Donor NK Cells in Allogeneic Bone Marrow Transplantation ¹

Janelle A. Olson; Robert Zeiser; Andreas Beilhack; Joshua J. Goldman; Robert S. Negrin

J Immunol (2009) 183 (5): 3219–3228.

View articletitled, Tissue-Specific Homing and Expansion of Donor NK Cells in Allogeneic Bone Marrow Transplantation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-β In Vivo ¹

Stefan Lienenklaus; Marius Cornitescu; Natalia Ziętara; Marcin Łyszkiewicz; Nelson Gekara; Jadwiga Jabłońska; Frank Edenhofer; Klaus Rajewsky; Dunja Bruder; Martin Hafner; Peter Staeheli; Siegfried Weiss

J Immunol (2009) 183 (5): 3229–3236.

View articletitled, Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-β In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Activation-Induced Cytidine Deaminase Expression and Activity in the Absence of Germinal Centers: Insights into Hyper-IgM Syndrome ¹

Masayuki Kuraoka; Dongmei Liao; Kaiyong Yang; Sallie D. Allgood; Marc C. Levesque; Garnett Kelsoe; Yoshihiro Ueda

J Immunol (2009) 183 (5): 3237–3248.

View articletitled, Activation-Induced Cytidine Deaminase Expression and Activity in the Absence of Germinal Centers: Insights into Hyper-IgM Syndrome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

The Binding of Antigenic Peptides to HLA-DR Is Influenced by Interactions between Pocket 6 and Pocket 9 ¹

Eddie A. James; Antonis K. Moustakas; John Bui; Randi Nouv; George K. Papadopoulos; William W. Kwok

J Immunol (2009) 183 (5): 3249–3258.

View articletitled, The Binding of Antigenic Peptides to HLA-DR Is Influenced by Interactions between Pocket 6 and Pocket 9<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Peroxisome Proliferator-Activated Receptor γ Agonist Down-Regulates IL-17 Expression in a Murine Model of Allergic Airway Inflammation ¹

Seoung Ju Park; Kyung Sun Lee; So Ri Kim; Kyung Hoon Min; Yeong Hun Choe; Hee Moon; Han Jung Chae; Wan Hee Yoo; Yong Chul Lee

J Immunol (2009) 183 (5): 3259–3267.

View articletitled, Peroxisome Proliferator-Activated Receptor γ Agonist Down-Regulates IL-17 Expression in a Murine Model of Allergic Airway Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Phosphorylation of Nur77 by the MEK-ERK-RSK Cascade Induces Mitochondrial Translocation and Apoptosis in T Cells ¹

Aibo Wang; Jonathan Rud; Chris M. Olson, Jr.; Juan Anguita; Barbara A. Osborne

J Immunol (2009) 183 (5): 3268–3277.

View articletitled, Phosphorylation of Nur77 by the MEK-ERK-RSK Cascade Induces Mitochondrial Translocation and Apoptosis in T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Membrane-Bound Fas Ligand Requires RIP1 for Efficient Activation of Caspase-8 within the Death-Inducing Signaling Complex ¹

Michael J. Morgan; You-Sun Kim; Zheng-gang Liu

J Immunol (2009) 183 (5): 3278–3284.

View articletitled, Membrane-Bound Fas Ligand Requires RIP1 for Efficient Activation of Caspase-8 within the Death-Inducing Signaling Complex<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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IMMUNOGENETICS

Ornithorhynchus anatinus (Platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Nonmammalian Tetrapods ¹^²

Yaofeng Zhao; Huiting Cui; Camilla M. Whittington; Zhiguo Wei; Xiaofeng Zhang; Ziding Zhang; Li Yu; Liming Ren; Xiaoxiang Hu; Yaping Zhang; Lars Hellman; Katherine Belov; Ning Li; Lennart Hammarström

J Immunol (2009) 183 (5): 3285–3293.

View articletitled, <em>Ornithorhynchus anatinus</em> (Platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Nonmammalian Tetrapods<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

Supplementary data

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HOST DEFENSE

Original Antigenic Sin Responses to Influenza Viruses ¹

Jin Hyang Kim; Ioanna Skountzou; Richard Compans; Joshy Jacob

J Immunol (2009) 183 (5): 3294–3301.

View articletitled, Original Antigenic Sin Responses to Influenza Viruses<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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NADPH Oxidase NOX2 Mediates Rapid Cellular Oxidation following ATP Stimulation of Endotoxin-Primed Macrophages ¹

Samantha F. Moore; Amanda B. MacKenzie

J Immunol (2009) 183 (5): 3302–3308.

View articletitled, NADPH Oxidase NOX2 Mediates Rapid Cellular Oxidation following ATP Stimulation of Endotoxin-Primed Macrophages<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Neutrophils Sequestered in the Liver Suppress the Proinflammatory Response of Kupffer Cells to Systemic Bacterial Infection ¹

Martin Holub; Chao-Wen Cheng; Stephanie Mott; Philip Wintermeyer; Nico van Rooijen; Stephen H. Gregory

J Immunol (2009) 183 (5): 3309–3316.

View articletitled, Neutrophils Sequestered in the Liver Suppress the Proinflammatory Response of Kupffer Cells to Systemic Bacterial Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Genetic Control of Severe Egg-Induced Immunopathology and IL-17 Production in Murine Schistosomiasis ¹

Patrick M. Smith; Mara G. Shainheit; Lindsey E. Bazzone; Laura I. Rutitzky; Alexander Poltorak; Miguel J. Stadecker

J Immunol (2009) 183 (5): 3317–3323.

View articletitled, Genetic Control of Severe Egg-Induced Immunopathology and IL-17 Production in Murine Schistosomiasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-12p40 and IL-18 Play Pivotal Roles in Orchestrating the Cell-Mediated Immune Response to a Poxvirus Infection ¹

Yang Wang; Geeta Chaudhri; Ronald J. Jackson; Gunasegaran Karupiah

J Immunol (2009) 183 (5): 3324–3331.

View articletitled, IL-12p40 and IL-18 Play Pivotal Roles in Orchestrating the Cell-Mediated Immune Response to a Poxvirus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CXCR2-Dependent Mucosal Neutrophil Influx Protects against Colitis-Associated Diarrhea Caused by an Attaching/Effacing Lesion-Forming Bacterial Pathogen ¹

Martina E. Spehlmann; Sara M. Dann; Petr Hruz; Elaine Hanson; Declan F. McCole; Lars Eckmann

J Immunol (2009) 183 (5): 3332–3343.

View articletitled, CXCR2-Dependent Mucosal Neutrophil Influx Protects against Colitis-Associated Diarrhea Caused by an Attaching/Effacing Lesion-Forming Bacterial Pathogen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Processing and Presentation of Variant Surface Glycoprotein Molecules to T Cells in African Trypanosomiasis ¹

Taylor R. Dagenais; Bailey E. Freeman; Karen P. Demick; Donna M. Paulnock; John M. Mansfield

J Immunol (2009) 183 (5): 3344–3355.

View articletitled, Processing and Presentation of Variant Surface Glycoprotein Molecules to T Cells in African Trypanosomiasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Sequential, Ordered Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 Domains ¹

Gerald K. K. Cham; Louise Turner; John Lusingu; Lasse Vestergaard; Bruno P. Mmbando; Jonathan D. Kurtis; Anja T. R. Jensen; Ali Salanti; Thomas Lavstsen; Thor G. Theander

J Immunol (2009) 183 (5): 3356–3363.

View articletitled, Sequential, Ordered Acquisition of Antibodies to <em>Plasmodium falciparum</em> Erythrocyte Membrane Protein 1 Domains<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Memory-Like CD8⁺ T Cells Generated during Homeostatic Proliferation Defer to Antigen-Experienced Memory Cells ¹

Kitty P. Cheung; Edward Yang; Ananda W. Goldrath

J Immunol (2009) 183 (5): 3364–3372.

View articletitled, Memory-Like CD8<sup>+</sup> T Cells Generated during Homeostatic Proliferation Defer to Antigen-Experienced Memory Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization ¹

Pia Dosenovic; Bimal Chakrabarti; Martina Soldemo; Iyadh Douagi; Mattias N. E. Forsell; Yuxing Li; Adhuna Phogat; Staffan Paulie; James Hoxie; Richard T. Wyatt; Gunilla B. Karlsson Hedestam

J Immunol (2009) 183 (5): 3373–3382.

View articletitled, Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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INFLAMMATION

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

Gerhard Krönke; Julia Katzenbeisser; Stefan Uderhardt; Mario M. Zaiss; Carina Scholtysek; Gernot Schabbauer; Alexander Zarbock; Marije I. Koenders; Roland Axmann; Jochen Zwerina; Hans W. Baenckler; Wim van den Berg; Reinhard E. Voll; Hartmut Kühn; Leo A. B. Joosten; Georg Schett

J Immunol (2009) 183 (5): 3383–3389.

View articletitled, 12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

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GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway ¹

Myeung Su Lee; Hun Soo Kim; Jeong-Tae Yeon; Sik-Won Choi; Churl Hong Chun; Han Bok Kwak; Jaemin Oh

J Immunol (2009) 183 (5): 3390–3399.

View articletitled, GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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A TLR2 Agonist in German Cockroach Frass Activates MMP-9 Release and Is Protective against Allergic Inflammation in Mice ¹

Kristen Page; John R. Ledford; Ping Zhou; Marsha Wills-Karp

J Immunol (2009) 183 (5): 3400–3408.

View articletitled, A TLR2 Agonist in German Cockroach Frass Activates MMP-9 Release and Is Protective against Allergic Inflammation in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function ¹

Márton Megyeri; Veronika Makó; László Beinrohr; Zoltán Doleschall; Zoltán Prohászka; László Cervenak; Péter Závodszky; Péter Gál

J Immunol (2009) 183 (5): 3409–3416.

View articletitled, Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IL-10 Is a Negative Regulatory Factor of CAWS-Vasculitis in CBA/J Mice as Assessed by Comparison with Bruton’s Tyrosine Kinase-Deficient CBA/N Mice ¹

Noriko N. Miura; Motohiko Komai; Yoshiyuki Adachi; Naoki Osada; Yosuke Kameoka; Kazuo Suzuki; Naohito Ohno

J Immunol (2009) 183 (5): 3417–3424.

View articletitled, IL-10 Is a Negative Regulatory Factor of CAWS-Vasculitis in CBA/J Mice as Assessed by Comparison with Bruton’s Tyrosine Kinase-Deficient CBA/N Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Differential Activation and Regulation of CXCR1 and CXCR2 by CXCL8 Monomer and Dimer ¹

Mohd W. Nasser; Sandeep K. Raghuwanshi; Delores J. Grant; Venkatakrishna R. Jala; Krishna Rajarathnam; Ricardo M. Richardson

J Immunol (2009) 183 (5): 3425–3432.

View articletitled, Differential Activation and Regulation of CXCR1 and CXCR2 by CXCL8 Monomer and Dimer<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Identification of Human Cathepsin G As a Functional Target of Boswellic Acids from the Anti-Inflammatory Remedy Frankincense ¹

Lars Tausch; Arne Henkel; Ulf Siemoneit; Daniel Poeckel; Nicole Kather; Lutz Franke; Bettina Hofmann; Gisbert Schneider; Carlo Angioni; Gerd Geisslinger; Carsten Skarke; Wolfgang Holtmeier; Tobias Beckhaus; Michael Karas; Johann Jauch; Oliver Werz

J Immunol (2009) 183 (5): 3433–3442.

View articletitled, Identification of Human Cathepsin G As a Functional Target of Boswellic Acids from the Anti-Inflammatory Remedy Frankincense<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Impaired Lung Dendritic Cell Migration and T Cell Stimulation Induced by Immunostimulatory Oligonucleotides Contribute to Reduced Allergic Airway Inflammation ¹

Hannelore Constabel; Metodi V. Stankov; Christina Hartwig; Thomas Tschernig; Georg M. N. Behrens

J Immunol (2009) 183 (5): 3443–3453.

View articletitled, Impaired Lung Dendritic Cell Migration and T Cell Stimulation Induced by Immunostimulatory Oligonucleotides Contribute to Reduced Allergic Airway Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Targeting Gut T Cell Ca²⁺ Release-Activated Ca²⁺ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

Antonio Di Sabatino; Laura Rovedatti; Rejbinder Kaur; Jonathan P. Spencer; Jon T. Brown; Valerie D. Morisset; Paolo Biancheri; Nicholas A. B. Leakey; Jonathan I. Wilde; Laurie Scott; Gino R. Corazza; Kevin Lee; Neel Sengupta; Charles H. Knowles; Martin J. Gunthorpe; Peter G. McLean; Thomas T. MacDonald; Laurens Kruidenier

J Immunol (2009) 183 (5): 3454–3462.

View articletitled, Targeting Gut T Cell Ca<sup>2+</sup> Release-Activated Ca<sup>2+</sup> Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

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Monocyte Chemoattractant Protein-1 (MCP-1), Not MCP-3, Is the Primary Chemokine Required for Monocyte Recruitment in Mouse Peritonitis Induced with Thioglycollate or Zymosan A ¹

Munehisa Takahashi; Carole Galligan; Lino Tessarollo; Teizo Yoshimura

J Immunol (2009) 183 (5): 3463–3471.

View articletitled, Monocyte Chemoattractant Protein-1 (MCP-1), Not MCP-3, Is the Primary Chemokine Required for Monocyte Recruitment in Mouse Peritonitis Induced with Thioglycollate or Zymosan A<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Lymphocytes in the Development of Lung Inflammation: A Role for Regulatory CD4⁺ T Cells in Indirect Pulmonary Lung Injury ¹

Fabienne Venet; Chun-Shiang Chung; Xin Huang; Joanne Lomas-Neira; Yaping Chen; Alfred Ayala

J Immunol (2009) 183 (5): 3472–3480.

View articletitled, Lymphocytes in the Development of Lung Inflammation: A Role for Regulatory CD4<sup>+</sup> T Cells in Indirect Pulmonary Lung Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Stimulatory and Inhibitory Killer Ig-Like Receptor Molecules Are Expressed and Functional on Lupus T Cells ¹

Dhiman Basu; Ying Liu; Ailing Wu; Sushma Yarlagadda; Gabriela J. Gorelik; Mariana J. Kaplan; Anura Hewagama; Robert C. Hinderer; Faith M. Strickland; Bruce C. Richardson

J Immunol (2009) 183 (5): 3481–3487.

View articletitled, Stimulatory and Inhibitory Killer Ig-Like Receptor Molecules Are Expressed and Functional on Lupus T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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γ-Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways ¹

Ying Wang; Qingqiong Luo; Yan Xu; Dechun Feng; Jian Fei; Qi Cheng; Lingyun Xu

J Immunol (2009) 183 (5): 3488–3495.

View articletitled, γ-Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Mannose-Binding Lectin (MBL) Substitution: Recovery of Opsonic Function In Vivo Lags behind MBL Serum Levels ¹

Nannette Brouwer; Florine N. J. Frakking; Marianne D. van de Wetering; Michel van Houdt; Margreet Hart; Ilona Kleine Budde; Paul F. W. Strengers; Inga Laursen; Gunnar Houen; Dirk Roos; Jens C. Jensenius; Huib N. Caron; Koert M. Dolman; Taco W. Kuijpers

J Immunol (2009) 183 (5): 3496–3504.

View articletitled, Mannose-Binding Lectin (MBL) Substitution: Recovery of Opsonic Function In Vivo Lags behind MBL Serum Levels<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Genetic Complementation Results in Augmented Autoantibody Responses to Lupus-Associated Antigens ¹

Davis L. Sim; Harini Bagavant; Yogesh M. Scindia; Yan Ge; Felicia Gaskin; Shu Man Fu; Umesh S. Deshmukh

J Immunol (2009) 183 (5): 3505–3511.

View articletitled, Genetic Complementation Results in Augmented Autoantibody Responses to Lupus-Associated Antigens<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Autoantibodies against Complement C1q Specifically Target C1q Bound on Early Apoptotic Cells ¹

Cornelia Bigler; Monica Schaller; Iryna Perahud; Michael Osthoff; Marten Trendelenburg

J Immunol (2009) 183 (5): 3512–3521.

View articletitled, Autoantibodies against Complement C1q Specifically Target C1q Bound on Early Apoptotic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HLA-DR Alleles in Amyloid β-Peptide Autoimmunity: A Highly Immunogenic Role for the DRB1*1501 Allele ¹

Victor Zota; Anna Nemirovsky; Rona Baron; Yair Fisher; Dennis J. Selkoe; Daniel M. Altmann; Howard L. Weiner; Alon Monsonego

J Immunol (2009) 183 (5): 3522–3530.

View articletitled, HLA-DR Alleles in Amyloid β-Peptide Autoimmunity: A Highly Immunogenic Role for the DRB1*1501 Allele<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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HLA-DQB10602 Determines Disease Susceptibility in a New “Humanized” Multiple Sclerosis Model in HLA-DR15 (DRB11501;DQB1*0602) Transgenic Mice ¹

Nathali Kaushansky; Daniel M. Altmann; Stephanie Ascough; Chella S. David; Hans Lassmann; Avraham Ben-Nun

J Immunol (2009) 183 (5): 3531–3541.

View articletitled, HLA-DQB1*0602 Determines Disease Susceptibility in a New “Humanized” Multiple Sclerosis Model in HLA-DR15 (DRB1*1501;DQB1*0602) Transgenic Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The MHC Haplotype H2b Converts Two Pure Nonlupus Mouse Strains to Producers of Antinuclear Antibodies ¹

Kristian Hannestad; Helge Scott

J Immunol (2009) 183 (5): 3542–3550.

View articletitled, The MHC Haplotype H2b Converts Two Pure Nonlupus Mouse Strains to Producers of Antinuclear Antibodies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

N. Nath; M. Khan; M. K. Paintlia; M. N. Hoda; S. Giri

J Immunol (2009) 183 (5): 3551.

View articletitled, Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

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Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production

M. T. Bailey; S. Kierstein; S. Sharma; M. Spaits; S. G. Kinsey; O. Tliba; J. F. Sheridan; R. A. Panettieri; A. Haczku

J Immunol (2009) 183 (5): 3551.

View articletitled, Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production

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Cover Image

Cover Image

On the cover: Modeled pocket 6 of HLA-DRB1*0901 (shown with p6Lys in foreground), uniquely accommodates a wide range of residues (acidic, aliphatic, polar, and basic), due to the arrangement of three acidic and two basic residues (shown in stick form). β9Lys swings into this pocket although normally found pointing into neighboring pocket 9. James, E. A., A. K. Moustakas, J. Bui, R. Nouv, G. K. Papadopoulos, and W. W. Kwok. 2009. The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9. J. Immunol. 183: 3249–3258.
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