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J Immunol (2009) 183 (6): 3557–3558.

View articletitled, IN THIS ISSUE

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LETTERS TO THE EDITOR

Comment on “Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency”

Paolo Ruggero Errante; Carolina Prando; Jacinta Bustamante; Walmir Cutrin Aragão Filho; Paulo Vitor Soelio Pereira; Jussara Rehder; Jean Laurent Casanova; Peter Newburger; Antônio Condino Neto

J Immunol (2009) 183 (6): 3559.

View articletitled, Comment on “Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency”

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Comment on “Spontaneous Autoimmunity Sufficiently Potent to Induce Diabetes Mellitus Is Insufficient to Protect against Insulinoma”

Dan E. H. Andersson; Åke Sjöholm

J Immunol (2009) 183 (6): 3559–3560.

View articletitled, Comment on “Spontaneous Autoimmunity Sufficiently Potent to Induce Diabetes Mellitus Is Insufficient to Protect against Insulinoma”

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Response to Comment on “Spontaneous Autoimmunity Sufficiently Potent to Induce Diabetes Mellitus Is Insufficient to Protect against Insulinoma”

Oliver F. Bathe; Christa Chatten

J Immunol (2009) 183 (6): 3560.

View articletitled, Response to Comment on “Spontaneous Autoimmunity Sufficiently Potent to Induce Diabetes Mellitus Is Insufficient to Protect against Insulinoma”

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BRIEF REVIEWS

B Cell Receptor and BAFF Receptor Signaling Regulation of B Cell Homeostasis ¹

Wasif N. Khan

J Immunol (2009) 183 (6): 3561–3567.

View articletitled, B Cell Receptor and BAFF Receptor Signaling Regulation of B Cell Homeostasis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CUTTING EDGE

Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity ¹

Bruno Moltedo; Carolina B. López; Michael Pazos; María Inés Becker; Tamar Hermesh; Thomas M. Moran

J Immunol (2009) 183 (6): 3569–3573.

View articletitled, Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Cutting Edge: TGF-β1 and IL-15 Induce FOXP3⁺ γδ Regulatory T Cells in the Presence of Antigen Stimulation ¹

Rita Casetti; Chiara Agrati; Marianne Wallace; Alessandra Sacchi; Federico Martini; Angelo Martino; Alessandra Rinaldi; Miroslav Malkovsky

J Immunol (2009) 183 (6): 3574–3577.

View articletitled, Cutting Edge: TGF-β1 and IL-15 Induce FOXP3<sup>+</sup> γδ Regulatory T Cells in the Presence of Antigen Stimulation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome ¹

Sophie Joly; Ning Ma; Jeffrey J. Sadler; David R. Soll; Suzanne L. Cassel; Fayyaz S. Sutterwala

J Immunol (2009) 183 (6): 3578–3581.

View articletitled, Cutting Edge: <em>Candida albicans</em> Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Immune Suppressive Activity and Lack of T Helper Differentiation Are Differentially Regulated in Natural Regulatory T Cells ¹

Wei-ping Zeng; Chawnshang Chang; Jiann-jyh Lai

J Immunol (2009) 183 (6): 3583–3590.

View articletitled, Immune Suppressive Activity and Lack of T Helper Differentiation Are Differentially Regulated in Natural Regulatory T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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IL-33 Activates Unprimed Murine Basophils Directly In Vitro and Induces Their In Vivo Expansion Indirectly by Promoting Hematopoietic Growth Factor Production ¹

Elke Schneider; Anne-France Petit-Bertron; Rachel Bricard; Mélanie Levasseur; Abdelrauf Ramadan; Jean-Philippe Girard; André Herbelin; Michel Dy

J Immunol (2009) 183 (6): 3591–3597.

View articletitled, IL-33 Activates Unprimed Murine Basophils Directly In Vitro and Induces Their In Vivo Expansion Indirectly by Promoting Hematopoietic Growth Factor Production<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Novel Human Interleukin-15 Agonists

Xiaoyun Zhu; Warren D. Marcus; Wenxin Xu; Hyung-il Lee; Kaiping Han; Jack O. Egan; Jason L. Yovandich; Peter R. Rhode; Hing C. Wong

J Immunol (2009) 183 (6): 3598–3607.

View articletitled, Novel Human Interleukin-15 Agonists

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An Accessory Role for B Cells in the IL-12-Induced Activation of Resting Mouse NK Cells ¹

Evette A. Haddad; Laura K. Senger; Fumio Takei

J Immunol (2009) 183 (6): 3608–3615.

View articletitled, An Accessory Role for B Cells in the IL-12-Induced Activation of Resting Mouse NK Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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A CD26-Controlled Cell Surface Cascade for Regulation of T Cell Motility and Chemokine Signals ¹

Zhiwen Liu; Marta Christensson; Anna Forslöw; Ingrid De Meester; Karl-Gösta Sundqvist

J Immunol (2009) 183 (6): 3616–3624.

View articletitled, A CD26-Controlled Cell Surface Cascade for Regulation of T Cell Motility and Chemokine Signals<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Early Triggering of Exclusive IFN-γ Responses of Human Vγ9Vδ2 T Cells by TLR-Activated Myeloid and Plasmacytoid Dendritic Cells ¹

Marie-Claire Devilder; Sophie Allain; Christelle Dousset; Marc Bonneville; Emmanuel Scotet

J Immunol (2009) 183 (6): 3625–3633.

View articletitled, Early Triggering of Exclusive IFN-γ Responses of Human Vγ9Vδ2 T Cells by TLR-Activated Myeloid and Plasmacytoid Dendritic Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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TLR3-Stimulated Dendritic Cells Up-regulate B7-H1 Expression and Influence the Magnitude of CD8 T Cell Responses to Tumor Vaccination ¹

Vesna Pulko; Xin Liu; Christopher J. Krco; Kimberley J. Harris; Xavier Frigola; Eugene D. Kwon; Haidong Dong

J Immunol (2009) 183 (6): 3634–3641.

View articletitled, TLR3-Stimulated Dendritic Cells Up-regulate B7-H1 Expression and Influence the Magnitude of CD8 T Cell Responses to Tumor Vaccination<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3 ¹

Elaine F. Kenny; Suzanne Talbot; Mei Gong; Douglas T. Golenbock; Clare E. Bryant; Luke A. J. O'Neill

J Immunol (2009) 183 (6): 3642–3651.

View articletitled, MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils ¹

Etsushi Kuroda; Victor Ho; Jens Ruschmann; Frann Antignano; Melisa Hamilton; Michael J. Rauh; Andrey Antov; Richard A. Flavell; Laura M. Sly; Gerald Krystal

J Immunol (2009) 183 (6): 3652–3660.

View articletitled, SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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CD21/35 Promotes Protective Immunity to Streptococcus pneumoniae through a Complement-Independent but CD19-Dependent Pathway That Regulates PD-1 Expression ¹

Karen M. Haas; Jonathan C. Poe; Thomas F. Tedder

J Immunol (2009) 183 (6): 3661–3671.

View articletitled, CD21/35 Promotes Protective Immunity to <em>Streptococcus pneumoniae</em> through a Complement-Independent but CD19-Dependent Pathway That Regulates PD-1 Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Estrogen Controls Vitamin D₃-Mediated Resistance to Experimental Autoimmune Encephalomyelitis by Controlling Vitamin D₃ Metabolism and Receptor Expression ¹

Faye E. Nashold; Karen M. Spach; Justin A. Spanier; Colleen E. Hayes

J Immunol (2009) 183 (6): 3672–3681.

View articletitled, Estrogen Controls Vitamin D<sub>3</sub>-Mediated Resistance to Experimental Autoimmune Encephalomyelitis by Controlling Vitamin D<sub>3</sub> Metabolism and Receptor Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Disruption of TGF-β Signaling Prevents the Generation of Tumor-Sensitized Regulatory T Cells and Facilitates Therapeutic Antitumor Immunity ¹

Ulf Petrausch; Shawn M. Jensen; Christopher Twitty; Christian H. Poehlein; Daniel P. Haley; Edwin B. Walker; Bernard A. Fox

J Immunol (2009) 183 (6): 3682–3689.

View articletitled, Disruption of TGF-β Signaling Prevents the Generation of Tumor-Sensitized Regulatory T Cells and Facilitates Therapeutic Antitumor Immunity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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XBP-1-Deficient Plasmablasts Show Normal Protein Folding but Altered Glycosylation and Lipid Synthesis ¹

Annette M. McGehee; Stephanie K. Dougan; Elizabeth J. Klemm; Guanghou Shui; Boyoun Park; You-Me Kim; Nicki Watson; Markus R. Wenk; Hidde L. Ploegh; Chih-Chi Andrew Hu

J Immunol (2009) 183 (6): 3690–3699.

View articletitled, XBP-1-Deficient Plasmablasts Show Normal Protein Folding but Altered Glycosylation and Lipid Synthesis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Kinin Danger Signals Proteolytically Released by Gingipain Induce Fimbriae-Specific IFN-γ- and IL-17-Producing T Cells in Mice Infected Intramucosally with Porphyromonas gingivalis¹

Ana Carolina Monteiro; Aline Scovino; Susane Raposo; Vinicius Mussa Gaze; Catia Cruz; Erik Svensjö; Marcelo Sampaio Narciso; Ana Paula Colombo; João B. Pesquero; Eduardo Feres-Filho; Ky-Anh Nguyen; Aneta Sroka; Jan Potempa; Julio Scharfstein

J Immunol (2009) 183 (6): 3700–3711.

View articletitled, Kinin Danger Signals Proteolytically Released by Gingipain Induce Fimbriae-Specific IFN-γ- and IL-17-Producing T Cells in Mice Infected Intramucosally with <em>Porphyromonas gingivalis</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Inflammatory Regulation by TLR3 in Acute Hepatitis ¹

Xiaoyan Xiao; Peng Zhao; Daniel Rodriguez-Pinto; Dake Qi; Octavian Henegariu; Lena Alexopoulou; Richard A. Flavell; F. Susan Wong; Li Wen

J Immunol (2009) 183 (6): 3712–3719.

View articletitled, Inflammatory Regulation by TLR3 in Acute Hepatitis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8⁺ T Lymphocytes ¹

Eva U. Wieckowski; Carmen Visus; Marta Szajnik; Miroslaw J. Szczepanski; Walter J. Storkus; Theresa L. Whiteside

J Immunol (2009) 183 (6): 3720–3730.

View articletitled, Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8<sup>+</sup> T Lymphocytes<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Foxp3-Deficient Regulatory T Cells Do Not Revert into Conventional Effector CD4⁺ T Cells but Constitute a Unique Cell Subset ¹^²

Michal Kuczma; Robert Podolsky; Nikhil Garge; Danielle Daniely; Rafal Pacholczyk; Leszek Ignatowicz; Piotr Kraj

J Immunol (2009) 183 (6): 3731–3741.

View articletitled, Foxp3-Deficient Regulatory T Cells Do Not Revert into Conventional Effector CD4<sup>+</sup> T Cells but Constitute a Unique Cell Subset<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

Supplementary data

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Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells ¹

Jian Zheng; Yinping Liu; Gang Qin; Ping-Lung Chan; Huawei Mao; Kwok-Tai Lam; David B. Lewis; Yu-Lung Lau; Wenwei Tu

J Immunol (2009) 183 (6): 3742–3750.

View articletitled, Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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The Sphingosine 1-Phosphate Receptor Agonist FTY720 Potently Inhibits Regulatory T Cell Proliferation In Vitro and In Vivo ¹^²

Anna Maria Wolf; Kathrin Eller; Robert Zeiser; Christoph Dürr; Ulrike V. Gerlach; Michael Sixt; Lydia Markut; Guenther Gastl; Alexander R. Rosenkranz; Dominik Wolf

J Immunol (2009) 183 (6): 3751–3760.

View articletitled, The Sphingosine 1-Phosphate Receptor Agonist FTY720 Potently Inhibits Regulatory T Cell Proliferation In Vitro and In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Helicobacter pylori Hp(2–20) Promotes Migration and Proliferation of Gastric Epithelial Cells by Interacting with Formyl Peptide Receptors In Vitro and Accelerates Gastric Mucosal Healing In Vivo ¹

Amato de Paulis; Nella Prevete; Francesca W. Rossi; Felice Rivellese; Fiamma Salerno; Gabriele Delfino; Bianca Liccardo; Elvira Avilla; Nunzia Montuori; Massimo Mascolo; Stefania Staibano; Rosa Marina Melillo; Giuseppe D'Argenio; Vittorio Ricci; Marco Romano; Gianni Marone

J Immunol (2009) 183 (6): 3761–3769.

View articletitled, <em>Helicobacter pylori</em> Hp(2–20) Promotes Migration and Proliferation of Gastric Epithelial Cells by Interacting with Formyl Peptide Receptors In Vitro and Accelerates Gastric Mucosal Healing In Vivo<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Blocking of CD27-CD70 Pathway by Anti-CD70 Antibody Ameliorates Joint Disease in Murine Collagen-Induced Arthritis

Ezogelin Oflazoglu; Tamar E. Boursalian; Weiping Zeng; Ana C. Edwards; Steve Duniho; Julie A. McEarchern; Che-Leung Law; Hans-Peter Gerber; Iqbal S. Grewal

J Immunol (2009) 183 (6): 3770–3777.

View articletitled, Blocking of CD27-CD70 Pathway by Anti-CD70 Antibody Ameliorates Joint Disease in Murine Collagen-Induced Arthritis

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Selectively Reduced Intracellular Proliferation of Salmonella enterica Serovar Typhimurium within APCs Limits Antigen Presentation and Development of a Rapid CD8 T Cell Response ¹

Homam Albaghdadi; Nirmal Robinson; Brett Finlay; Lakshmi Krishnan; Subash Sad

J Immunol (2009) 183 (6): 3778–3787.

View articletitled, Selectively Reduced Intracellular Proliferation of <em>Salmonella enterica</em> Serovar Typhimurium within APCs Limits Antigen Presentation and Development of a Rapid CD8 T Cell Response<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Alveolar Macrophages and Lung Dendritic Cells Sense RNA and Drive Mucosal IgA Responses

Juliana Bessa; Andrea Jegerlehner; Heather J. Hinton; Paul Pumpens; Philippe Saudan; Pascal Schneider; Martin F. Bachmann

J Immunol (2009) 183 (6): 3788–3799.

View articletitled, Alveolar Macrophages and Lung Dendritic Cells Sense RNA and Drive Mucosal IgA Responses

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Characterization of FIBCD1 as an Acetyl Group-Binding Receptor That Binds Chitin ¹

Anders Schlosser; Theresa Thomsen; Jesper B. Moeller; Ole Nielsen; Ida Tornøe; Jan Mollenhauer; Søren K. Moestrup; Uffe Holmskov

J Immunol (2009) 183 (6): 3800–3809.

View articletitled, Characterization of FIBCD1 as an Acetyl Group-Binding Receptor That Binds Chitin<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Factor G Utilizes a Carbohydrate-Binding Cleft That Is Conserved between Horseshoe Crab and Bacteria for the Recognition of β-1,3-d-Glucans ¹

Yuki Ueda; Shuhei Ohwada; Yoshito Abe; Toshio Shibata; Manabu Iijima; Yukiko Yoshimitsu; Takumi Koshiba; Munehiro Nakata; Tadashi Ueda; Shun-ichiro Kawabata

J Immunol (2009) 183 (6): 3810–3818.

View articletitled, Factor G Utilizes a Carbohydrate-Binding Cleft That Is Conserved between Horseshoe Crab and Bacteria for the Recognition of β-1,3-<span class="small-caps">d</span>-Glucans<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Divergent Roles of RelA and c-Rel in Establishing Chromosomal Loops upon Activation of the Igκ Gene ¹

Zhe Liu; Zhenyi Ma; Lance S. Terada; William T. Garrard

J Immunol (2009) 183 (6): 3819–3830.

View articletitled, Divergent Roles of RelA and c-Rel in Establishing Chromosomal Loops upon Activation of the Igκ Gene<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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MEKK1 Binds HECT E3 Ligase Itch by Its Amino-Terminal RING Motif to Regulate Th2 Cytokine Gene Expression ¹

Thomas Enzler; Xing Chang; Valeria Facchinetti; Gerry Melino; Michael Karin; Bing Su; Ewen Gallagher

J Immunol (2009) 183 (6): 3831–3838.

View articletitled, MEKK1 Binds HECT E3 Ligase Itch by Its Amino-Terminal RING Motif to Regulate Th2 Cytokine Gene Expression<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Temporal Induction Pattern of STAT4 Target Genes Defines Potential for Th1 Lineage-Specific Programming ¹

Seth R. Good; Vivian T. Thieu; Anubhav N. Mathur; Qing Yu; Gretta L. Stritesky; Norman Yeh; John T. O'Malley; Narayanan B. Perumal; Mark H. Kaplan

J Immunol (2009) 183 (6): 3839–3847.

View articletitled, Temporal Induction Pattern of STAT4 Target Genes Defines Potential for Th1 Lineage-Specific Programming<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Specific Requirements for Vγ9Vδ2 T Cell Stimulation by a Natural Adenylated Phosphoantigen ¹

Pierre Vantourout; Jayati Mookerjee-Basu; Corinne Rolland; Frédéric Pont; Hélène Martin; Christian Davrinche; Laurent O. Martinez; Bertrand Perret; Xavier Collet; Christian Périgaud; Suzanne Peyrottes; Eric Champagne

J Immunol (2009) 183 (6): 3848–3857.

View articletitled, Specific Requirements for Vγ9Vδ2 T Cell Stimulation by a Natural Adenylated Phosphoantigen<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Expression of IgM, IgD, and IgY in a Reptile, Anolis carolinensis¹

Zhiguo Wei; Qian Wu; Liming Ren; Xiaoxiang Hu; Ying Guo; Gregory W. Warr; Lennart Hammarström; Ning Li; Yaofeng Zhao

J Immunol (2009) 183 (6): 3858–3864.

View articletitled, Expression of IgM, IgD, and IgY in a Reptile, <em>Anolis carolinensis</em><sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Cell-Intrinsic Role for Mst1 in Regulating Thymocyte Egress ¹

Yongli Dong; Xingrong Du; Jian Ye; Min Han; Tian Xu; Yuan Zhuang; Wufan Tao

J Immunol (2009) 183 (6): 3865–3872.

View articletitled, A Cell-Intrinsic Role for <em>Mst1</em> in Regulating Thymocyte Egress<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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IMMUNOGENETICS

β-Catenin/Tcf Determines the Outcome of Thymic Selection in Response to αβTCR Signaling ¹

Damian Kovalovsky; Yu Yu; Marei Dose; Anastasia Emmanouilidou; Tassos Konstantinou; Kristine Germar; Katayoun Aghajani; Zhuyan Guo; Malay Mandal; Fotini Gounari

J Immunol (2009) 183 (6): 3873–3884.

View articletitled, β-Catenin/Tcf Determines the Outcome of Thymic Selection in Response to αβTCR Signaling<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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HOST DEFENSE

Galactoxylomannan-Mediated Immunological Paralysis Results from Specific B Cell Depletion in the Context of Widespread Immune System Damage ¹^²

Magdia De Jesus; André Moraes Nicola; Susana Frases; Ian R. Lee; Steven Mieses; Arturo Casadevall

J Immunol (2009) 183 (6): 3885–3894.

View articletitled, Galactoxylomannan-Mediated Immunological Paralysis Results from Specific B Cell Depletion in the Context of Widespread Immune System Damage<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup><sup><a href="javascript:;" reveal-id="FN2" data-open="FN2" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>2</sup></a></sup>

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Persistent Viral Infection Elevates Central Nervous System MHC Class I through Chronic Production of Interferons ¹

Phi Truong; Sara Heydari; Lucile Garidou; Dorian B. McGavern

J Immunol (2009) 183 (6): 3895–3905.

View articletitled, Persistent Viral Infection Elevates Central Nervous System MHC Class I through Chronic Production of Interferons<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Disruption of Th2 Immunity Results in a Gender-Specific Expansion of IL-13 Producing Accessory NK Cells during Helminth Infection ¹

Matthew R. Hepworth; Richard K. Grencis

J Immunol (2009) 183 (6): 3906–3914.

View articletitled, Disruption of Th2 Immunity Results in a Gender-Specific Expansion of IL-13 Producing Accessory NK Cells during Helminth Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Tuberculosis-Associated Immune Restoration Syndrome in HIV-1-Infected Patients Involves Tuberculin-Specific CD4 Th1 Cells and KIR-Negative γδ T Cells ¹

Anne Bourgarit; Guislaine Carcelain; Assia Samri; Christophe Parizot; Matthieu Lafaurie; Sophie Abgrall; Veronique Delcey; Eric Vicaut; Daniel Sereni; Brigitte Autran; the PARADOX Study Group

J Immunol (2009) 183 (6): 3915–3923.

View articletitled, Tuberculosis-Associated Immune Restoration Syndrome in HIV-1-Infected Patients Involves Tuberculin-Specific CD4 Th1 Cells and KIR-Negative γδ T Cells<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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The Two Groups of Zebrafish Virus-Induced Interferons Signal via Distinct Receptors with Specific and Shared Chains ¹

Dina Aggad; Martine Mazel; Pierre Boudinot; Knud Erik Mogensen; Ole Jensen Hamming; Rune Hartmann; Sergei Kotenko; Philippe Herbomel; Georges Lutfalla; Jean-Pierre Levraud

J Immunol (2009) 183 (6): 3924–3931.

View articletitled, The Two Groups of Zebrafish Virus-Induced Interferons Signal via Distinct Receptors with Specific and Shared Chains<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CD4⁺ T Cell Help Has an Epitope-Dependent Impact on CD8⁺ T Cell Memory Inflation during Murine Cytomegalovirus Infection ¹

Christopher M. Snyder; Andrea Loewendorf; Elizabeth L. Bonnett; Michael Croft; Chris A. Benedict; Ann B. Hill

J Immunol (2009) 183 (6): 3932–3941.

View articletitled, CD4<sup>+</sup> T Cell Help Has an Epitope-Dependent Impact on CD8<sup>+</sup> T Cell Memory Inflation during Murine Cytomegalovirus Infection<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome ¹

Raúl Muñoz-Planillo; Luigi Franchi; Lloyd S. Miller; Gabriel Núñez

J Immunol (2009) 183 (6): 3942–3948.

View articletitled, A Critical Role for Hemolysins and Bacterial Lipoproteins in <em>Staphylococcus aureus</em>-Induced Activation of the Nlrp3 Inflammasome<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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INFLAMMATION

Eosinophil Cationic Protein (ECP) Is Processed during Secretion ¹

Charlotte Woschnagg; Jenny Rubin; Per Venge

J Immunol (2009) 183 (6): 3949–3954.

View articletitled, Eosinophil Cationic Protein (ECP) Is Processed during Secretion<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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ERK and Not p38 Pathway Is Required for IL-12 Restoration of T Cell IL-2 and IFN-γ in a Rodent Model of Alcohol Intoxication and Burn Injury ¹

Xiaoling Li; Irshad H. Chaudry; Mashkoor A. Choudhry

J Immunol (2009) 183 (6): 3955–3962.

View articletitled, ERK and Not p38 Pathway Is Required for IL-12 Restoration of T Cell IL-2 and IFN-γ in a Rodent Model of Alcohol Intoxication and Burn Injury<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Regulation of Murine Splenic B Cell CR3 Expression by Complement Component 3 ¹

Amanda C. Jacobson; Kirstin M. Roundy; Janis J. Weis; John H. Weis

J Immunol (2009) 183 (6): 3963–3970.

View articletitled, Regulation of Murine Splenic B Cell CR3 Expression by Complement Component 3<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Deficiency of Endothelial Heparan Sulfates Attenuates Allergic Airway Inflammation ¹

Riaz I. Zuberi; Xiao Na Ge; Shuxia Jiang; Nooshin S. Bahaie; Bit Na Kang; Reza M. Hosseinkhani; Elizabeth M. Frenzel; Mark M. Fuster; Jeffrey D. Esko; Savita P. Rao; P. Sriramarao

J Immunol (2009) 183 (6): 3971–3979.

View articletitled, Deficiency of Endothelial Heparan Sulfates Attenuates Allergic Airway Inflammation<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Both Complement and IgG Fc Receptors Are Required for Development of Attenuated Antiglomerular Basement Membrane Nephritis in Mice ¹

Marielle A. Otten; Tom W. L. Groeneveld; Roelof Flierman; Maria Pia Rastaldi; Leendert A. Trouw; Maria C. Faber-Krol; Annemieke Visser; Maria C. Essers; Jill Claassens; J. Sjef Verbeek; Cees van Kooten; Anja Roos; Mohamed R. Daha

J Immunol (2009) 183 (6): 3980–3988.

View articletitled, Both Complement and IgG Fc Receptors Are Required for Development of Attenuated Antiglomerular Basement Membrane Nephritis in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain ¹

Susan Carpenter; Thaddeus Carlson; Jerome Dellacasagrande; Amaya Garcia; Sharon Gibbons; Paul Hertzog; Anthony Lyons; Lih-Ling Lin; Marina Lynch; Tom Monie; Caroline Murphy; Katherine J. Seidl; Christine Wells; Aisling Dunne; Luke A. J. O'Neill

J Immunol (2009) 183 (6): 3989–3995.

View articletitled, TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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TC1(C8orf4) Is a Novel Endothelial Inflammatory Regulator Enhancing NF-κB Activity ¹

Jungtae Kim; Yunlim Kim; Hyun-Taek Kim; Dong Wook Kim; Yunhi Ha; Jihun Kim; Cheol-Hee Kim; Inchul Lee; Kyuyoung Song

J Immunol (2009) 183 (6): 3996–4002.

View articletitled, TC1(C8orf4) Is a Novel Endothelial Inflammatory Regulator Enhancing NF-κB Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF ¹

Laeticia Kolly; Mahir Karababa; Leo A. B. Joosten; Sharmal Narayan; Roberto Salvi; Virginie Pétrilli; Jurg Tschopp; Wim B. van den Berg; Alexander Kai-Lik So; Nathalie Busso

J Immunol (2009) 183 (6): 4003–4012.

View articletitled, Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Eosinophil Ribonucleases and Their Cutaneous Lesion-Forming Activity ¹

Douglas A. Plager; Mark D. P. Davis; Amy G. Andrews; Michael J. Coenen; Terry J. George; Gerald J. Gleich; Kristin M. Leiferman

J Immunol (2009) 183 (6): 4013–4020.

View articletitled, Eosinophil Ribonucleases and Their Cutaneous Lesion-Forming Activity<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages

Unja Martin; John Scholler; Jesse Gurgel; Blair Renshaw; John E. Sims; Christopher A. Gabel

J Immunol (2009) 183 (6): 4021–4030.

View articletitled, Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages

Supplementary data

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A Pivotal Role of Endothelial-Specific NF-κB Signaling in the Pathogenesis of Septic Shock and Septic Vascular Dysfunction ¹

Jianqiang Ding; Dongmei Song; Xiaobing Ye; Shu Fang Liu

J Immunol (2009) 183 (6): 4031–4038.

View articletitled, A Pivotal Role of Endothelial-Specific NF-κB Signaling in the Pathogenesis of Septic Shock and Septic Vascular Dysfunction<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Complement C3a Regulates Late Asthmatic Response and Airway Hyperresponsiveness in Mice ¹

Nobuaki Mizutani; Takeshi Nabe; Shin Yoshino

J Immunol (2009) 183 (6): 4039–4046.

View articletitled, Complement C3a Regulates Late Asthmatic Response and Airway Hyperresponsiveness in Mice<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Neutrophil-Derived Hyperresistinemia in Severe Acute Streptococcal Infections ¹

Linda Johansson; Anna Linnér; Jonas Sundén-Cullberg; Axana Haggar; Heiko Herwald; Karin Loré; Carl-Johan Treutiger; Anna Norrby-Teglund

J Immunol (2009) 183 (6): 4047–4054.

View articletitled, Neutrophil-Derived Hyperresistinemia in Severe Acute Streptococcal Infections<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Site-Specific Carboxypeptidase B1 Tyrosine Nitration and Pathophysiological Implications following Its Physical Association with Nitric Oxide Synthase-3 in Experimental Sepsis ¹

Saurabh Chatterjee; Olivier Lardinois; Marcelo G. Bonini; Suchandra Bhattacharjee; Krisztian Stadler; Jean Corbett; Leesa J. Deterding; Kenneth B. Tomer; Maria Kadiiska; Ronald P. Mason

J Immunol (2009) 183 (6): 4055–4066.

View articletitled, Site-Specific Carboxypeptidase B1 Tyrosine Nitration and Pathophysiological Implications following Its Physical Association with Nitric Oxide Synthase-3 in Experimental Sepsis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CLINICAL IMMUNOLOGY

Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis ¹

J Immunol (2009) 183 (6): 4067–4076.

View articletitled, Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Expression of Tolerance Associated Gene-1, a Mitochondrial Protein Inhibiting T Cell Activation, Can Be Used to Predict Response to Immune Modulating Therapies ¹

Kathrin Keeren; Markus Friedrich; Inga Gebuhr; Sandra Philipp; Robert Sabat; Wolfram Sterry; Christine Brandt; Christian Meisel; Gerald Grütz; Hans-Dieter Volk; Birgit Sawitzki

J Immunol (2009) 183 (6): 4077–4087.

View articletitled, Expression of Tolerance Associated Gene-1, a Mitochondrial Protein Inhibiting T Cell Activation, Can Be Used to Predict Response to Immune Modulating Therapies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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A Novel Humanized Neonatal Autoimmune Blistering Skin Disease Model Induced by Maternally Transferred Antibodies ¹

Wataru Nishie; Daisuke Sawamura; Ken Natsuga; Satoru Shinkuma; Maki Goto; Akihiko Shibaki; Hideyuki Ujiie; Edit Olasz; Kim B. Yancey; Hiroshi Shimizu

J Immunol (2009) 183 (6): 4088–4093.

View articletitled, A Novel Humanized Neonatal Autoimmune Blistering Skin Disease Model Induced by Maternally Transferred Antibodies<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Direct Expansion of Human Allospecific FoxP3⁺CD4⁺ Regulatory T Cells with Allogeneic B Cells for Therapeutic Application

Leo C. Chen; Julio C. Delgado; Peter E. Jensen; Xinjian Chen

J Immunol (2009) 183 (6): 4094–4102.

View articletitled, Direct Expansion of Human Allospecific FoxP3<sup>+</sup>CD4<sup>+</sup> Regulatory T Cells with Allogeneic B Cells for Therapeutic Application

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Chronic Human Infection with Trypanosoma cruzi Drives CD4⁺ T Cells to Immune Senescence ¹

María Cecilia Albareda; Gabriela Carina Olivera; Susana A. Laucella; María Gabriela Alvarez; Esteban Rodrigo Fernandez; Bruno Lococo; Rodolfo Viotti; Rick L. Tarleton; Miriam Postan

J Immunol (2009) 183 (6): 4103–4108.

View articletitled, Chronic Human Infection with <em>Trypanosoma cruzi</em> Drives CD4<sup>+</sup> T Cells to Immune Senescence<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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Resident Dendritic Cells Prevent Postischemic Acute Renal Failure by Help of Single Ig IL-1 Receptor-Related Protein ¹

Maciej Lech; Alejandro Avila-Ferrufino; Ramanjaneyulu Allam; Stephan Segerer; Alexander Khandoga; Fritz Krombach; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders

J Immunol (2009) 183 (6): 4109–4118.

View articletitled, Resident Dendritic Cells Prevent Postischemic Acute Renal Failure by Help of Single Ig IL-1 Receptor-Related Protein<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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De Novo Generation and Enhanced Suppression of Human CD4⁺CD25⁺ Regulatory T Cells by Retinoic Acid ¹

Jun Wang; Tom W. J. Huizinga; Rene E. M. Toes

J Immunol (2009) 183 (6): 4119–4126.

View articletitled, De Novo Generation and Enhanced Suppression of Human CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cells by Retinoic Acid<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

Supplementary data

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Therapeutic Antibody Targeting of CD97 in Experimental Arthritis: the Role of Antigen Expression, Shedding, and Internalization on the Pharmacokinetics of Anti-CD97 Monoclonal Antibody 1B2 ¹

Dorien M. de Groot; Gerard Vogel; John Dulos; Leonie Teeuwen; Karin Stebbins; Jörg Hamann; Bronwyn M. Owens; Hans van Eenennaam; Ebo Bos; Annemieke M. Boots

J Immunol (2009) 183 (6): 4127–4134.

View articletitled, Therapeutic Antibody Targeting of CD97 in Experimental Arthritis: the Role of Antigen Expression, Shedding, and Internalization on the Pharmacokinetics of Anti-CD97 Monoclonal Antibody 1B2<sup><a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal"><sup>1</sup></a></sup>

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CORRECTIONS

Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis

M. Manocha; R. Svend; A. Laouar; G. Liao; A. Bhan; J. Borst; C. Terhorst; N. Manjunath

J Immunol (2009) 183 (6): 4135.

View articletitled, Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis

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A central role for transcription factor C/EBP-β in regulating CD1d gene expression in human keratinocytes

H. Sikder; Y. Zhao; A. Balato; A. Chapoval; R. Fishelevich; P. Gade; I. S. Singh; D. V. Kalvakolanu; P. F. Johnson; A. A. Gaspari

J Immunol (2009) 183 (6): 4135.

View articletitled, A central role for transcription factor C/EBP-β in regulating CD1d gene expression in human keratinocytes

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IL-17A controls IL-17F production and maintains blood neutrophil counts in mice

S. von Vietinghoff; K. Ley

J Immunol (2009) 183 (6): 4136.

View articletitled, IL-17A controls IL-17F production and maintains blood neutrophil counts in mice

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Cover Image

Cover Image

On the cover: Zebrafish embryo, 36 h post-fertilization, double in situ hybridization for tc1a (blue) and fli1 (brown). TC1(C8orf4) is a novel regulator of endothelial inflammation among vertebrates. Zebrafish has two homologs, tc1a and tc1b. In embryos, tc1a is mostly expressed in developing blood vessels showing fli1 and in the brain. Hematopoietic precursor cells express tc1b. Kim J., Y. Kim, H.-T. Kim, D. W. Kim, Y. Ha, J. Kim, C.-H. Kim, I. Lee, and K. Song. 2009. TC1(C8orf4) is a novel endothelial inflammatory regulator enhancing NF-κB activity. J. Immunol 183: 3996–4002.
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