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J Immunol (2010) 184 (12): 6561–6562.

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BRIEF REVIEWS

Signaling Pathways in T Follicular Helper Cells

Julia Rolf; Kirsten Fairfax; Martin Turner

J Immunol (2010) 184 (12): 6563–6568.

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CUTTING EDGE

Cutting Edge: Lack of High Affinity Competition for Peptide in Polyclonal CD4⁺ Responses Unmasks IL-4 Production

Joshua D. Milner; Nicolas Fazilleau; Michael McHeyzer-Williams; William Paul

J Immunol (2010) 184 (12): 6569–6573.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Vasodilator-Stimulated Phosphoprotein Regulates Inside-Out Signaling of β₂ Integrins in Neutrophils

Ravi K. Deevi; Madhuri Koney-Dash; Adrien Kissenpfennig; James A. Johnston; Kai Schuh; Ulrich Walter; Karim Dib

J Immunol (2010) 184 (12): 6575–6584.

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Control of T Cell Reactivation by Regulatory Qa-1–Restricted CD8⁺ T Cells

Aditi Varthaman; Jamila Khallou-Laschet; Marc Clement; Giulia Fornasa; Hye-Jung Kim; Anh-Thu Gaston; Michael Dussiot; Giuseppina Caligiuri; André Herbelin; Srinivas Kaveri; Harvey Cantor; Antonino Nicoletti

J Immunol (2010) 184 (12): 6585–6591.

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High-Affinity B Cell Receptor Ligation by Cognate Antigen Induces Cytokine-Independent Isotype Switching

Marian L. Turner; Lynn M. Corcoran; Robert Brink; Philip D. Hodgkin

J Immunol (2010) 184 (12): 6592–6599.

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Human CD34-Derived Myeloid Dendritic Cell Development Requires Intact Phosphatidylinositol 3-Kinase–Protein Kinase B–Mammalian Target of Rapamycin Signaling

Lianne van de Laar; Miranda Buitenhuis; Felix M. Wensveen; Harry L.A. Janssen; Paul J. Coffer; Andrea M. Woltman

J Immunol (2010) 184 (12): 6600–6611.

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Human Intestinal Lamina Propria CD1c⁺ Dendritic Cells Display an Activated Phenotype at Steady State and Produce IL-23 in Response to TLR7/8 Stimulation

Stephanie M. Dillon; Lisa M. Rogers; Rawleigh Howe; Lydia A. Hostetler; Jonathan Buhrman; Martin D. McCarter; Cara C. Wilson

J Immunol (2010) 184 (12): 6612–6621.

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Effects of Polyclonal IgG Derived from Patients with Different Clinical Types of the Antiphospholipid Syndrome on Monocyte Signaling Pathways

Anastasia Lambrianides; Christopher J. Carroll; Silvia S. Pierangeli; Charis Pericleous; Ware Branch; Jurhee Rice; David S. Latchman; Paul Townsend; David A. Isenberg; Anisur Rahman; Ian P. Giles

J Immunol (2010) 184 (12): 6622–6628.

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TGF-β–Induced Myelin Peptide-Specific Regulatory T Cells Mediate Antigen-Specific Suppression of Induction of Experimental Autoimmune Encephalomyelitis

Hong Zhang; Joseph R. Podojil; Judy Chang; Xunrong Luo; Stephen D. Miller

J Immunol (2010) 184 (12): 6629–6636.

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Increased Hematopoietic Cells in the mertk^−/− Mouse Peritoneal Cavity: A Result of Augmented Migration

Julie C. Williams; Nikki J. Wagner; H. Shelton Earp; Barbara J. Vilen; Glenn K. Matsushima

J Immunol (2010) 184 (12): 6637–6648.

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NK Cells Delay Allograft Rejection in Lymphopenic Hosts by Downregulating the Homeostatic Proliferation of CD8⁺ T Cells

Daniel Zecher; Qi Li; Martin H. Oberbarnscheidt; Anthony J. Demetris; Warren D. Shlomchik; David M. Rothstein; Fadi G. Lakkis

J Immunol (2010) 184 (12): 6649–6657.

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TLR Stimulation of Prostate Tumor Cells Induces Chemokine-Mediated Recruitment of Specific Immune Cell Types

Roberta Galli; Donatella Starace; Roberta Busà; Daniela F. Angelini; Alessio Paone; Paola De Cesaris; Antonio Filippini; Claudio Sette; Luca Battistini; Elio Ziparo; Anna Riccioli

J Immunol (2010) 184 (12): 6658–6669.

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Synergy between IL-15 and Id2 Promotes the Expansion of Human NK Progenitor Cells, Which Can Be Counteracted by the E Protein HEB Required To Drive T Cell Development

Remko Schotte; Wendy Dontje; Maho Nagasawa; Yuko Yasuda; Arjen Q. Bakker; Hergen Spits; Bianca Blom

J Immunol (2010) 184 (12): 6670–6679.

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Phosphoantigens Overcome Human TCRVγ9⁺ γδ Cell Immunosuppression by TGF-β: Relevance for Cancer Immunotherapy

Aude-Hélène Capietto; Ludovic Martinet; Delphine Cendron; Séverine Fruchon; Frédéric Pont; Jean-Jacques Fournié

J Immunol (2010) 184 (12): 6680–6687.

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Human β-Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

Johann Röhrl; De Yang; Joost J. Oppenheim; Thomas Hehlgans

J Immunol (2010) 184 (12): 6688–6694.

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Dendritic Cell-Directed CTLA-4 Engagement during Pancreatic β Cell Antigen Presentation Delays Type 1 Diabetes

Subha Karumuthil-Melethil; Nicolas Perez; Ruobing Li; Bellur S. Prabhakar; Mark J. Holterman; Chenthamarakshan Vasu

J Immunol (2010) 184 (12): 6695–6708.

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Human Tumor Antigen-Specific Helper and Regulatory T Cells Share Common Epitope Specificity but Exhibit Distinct T Cell Repertoire

Julien Fourcade; Zhaojun Sun; Pavol Kudela; Bratislav Janjic; John M. Kirkwood; Talal El-Hafnawy; Hassane M. Zarour

J Immunol (2010) 184 (12): 6709–6718.

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Distinct Roles for IL-2 and IL-15 in the Differentiation and Survival of CD8⁺ Effector and Memory T Cells

Diana M. Mitchell; Eugene V. Ravkov; Matthew A. Williams

J Immunol (2010) 184 (12): 6719–6730.

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Impact of TCR Reactivity and HLA Phenotype on Naive CD8 T Cell Frequency in Humans

François Legoux; Emilie Debeaupuis; Klara Echasserieau; Henri De La Salle; Xavier Saulquin; Marc Bonneville

J Immunol (2010) 184 (12): 6731–6738.

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Loss of Naive T Cells and Repertoire Constriction Predict Poor Response to Vaccination in Old Primates

Luka Čičin-Šain; Sue Smyk-Paerson; Noreen Currier; Laura Byrd; Caroline Koudelka; Tammie Robinson; Gwendolyn Swarbrick; Shane Tackitt; Alfred Legasse; Miranda Fischer; Dragana Nikolich-Žugich; Byung Park; Theodore Hobbs; Cynthia J. Doane; Motomi Mori; Michael T. Axthelm; Deborah A. Lewinsohn; Janko Nikolich-Žugich

J Immunol (2010) 184 (12): 6739–6745.

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PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals

Damian Kovalovsky; Eric S. Alonzo; Olisambu U. Uche; Maggie Eidson; Kim E. Nichols; Derek B. Sant’Angelo

J Immunol (2010) 184 (12): 6746–6755.

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Homeostatic Expansion and Phenotypic Conversion of Human T Cells Depend on Peripheral Interactions with APCs

Takashi Onoe; Hannes Kalscheuer; Meredith Chittenden; Guiling Zhao; Yong-Guang Yang; Megan Sykes

J Immunol (2010) 184 (12): 6756–6765.

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Sepsis-Induced Apoptosis Leads to Active Suppression of Delayed-Type Hypersensitivity by CD8⁺ Regulatory T Cells through a TRAIL-Dependent Mechanism

Jacqueline Unsinger; Hirotaka Kazama; Jacqueline S. McDonough; Thomas S. Griffith; Richard S. Hotchkiss; Thomas A. Ferguson

J Immunol (2010) 184 (12): 6766–6772.

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MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4⁺ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

Wen Pan; Shu Zhu; Min Yuan; Huijuan Cui; Lijia Wang; Xiaobing Luo; Jia Li; Haibo Zhou; Yuanjia Tang; Nan Shen

J Immunol (2010) 184 (12): 6773–6781.

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B Cell Development in GALT: Role of Bacterial Superantigen-Like Molecules

Kari M. Severson; Michael Mallozzi; Adam Driks; Katherine L. Knight

J Immunol (2010) 184 (12): 6782–6789.

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NK Cell Regulation of CD4 T Cell-Mediated Graft-versus-Host Disease

Magali Noval Rivas; Marc Hazzan; Kathleen Weatherly; Florence Gaudray; Isabelle Salmon; Michel Y. Braun

J Immunol (2010) 184 (12): 6790–6798.

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Downregulation of Th17 Cells in the Small Intestine by Disruption of Gut Flora in the Absence of Retinoic Acid

Hye-Ran Cha; Sun-Young Chang; Jae-Hoon Chang; Jae-Ouk Kim; Jin-Young Yang; Chang-Hoon Kim; Mi-Na Kweon

J Immunol (2010) 184 (12): 6799–6806.

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Differential Roles of IL-2–Inducible T Cell Kinase-Mediated TCR Signals in Tissue-Specific Localization and Maintenance of Skin Intraepithelial T Cells

Mingcan Xia; Qian Qi; Yan Jin; David L. Wiest; Avery August; Na Xiong

J Immunol (2010) 184 (12): 6807–6814.

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Immunosuppressive Effect of Quercetin on Dendritic Cell Activation and Function

Ren-Yeong Huang; Yen-Ling Yu; Wan-Chien Cheng; Chun-Nan OuYang; Earl Fu; Ching-Liang Chu

J Immunol (2010) 184 (12): 6815–6821.

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Invariant NKT Cell Development Requires a Full Complement of Functional CD3 ζ Immunoreceptor Tyrosine-Based Activation Motifs

Amy M. Becker; Jon S. Blevins; Farol L. Tomson; Jennifer L. Eitson; Jennifer J. Medeiros; Felix Yarovinsky; Michael V. Norgard; Nicolai S. C. van Oers

J Immunol (2010) 184 (12): 6822–6832.

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Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

Dominique B. Hoelzinger; Shannon E. Smith; Noweeda Mirza; Ana Lucia Dominguez; Soraya Zorro Manrique; Joseph Lustgarten

J Immunol (2010) 184 (12): 6833–6842.

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An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation

Andrew M. Platt; Calum C. Bain; Yvonne Bordon; David P. Sester; Allan McI. Mowat

J Immunol (2010) 184 (12): 6843–6854.

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Fusion Proteins for Versatile Antigen Targeting to Cell Surface Receptors Reveal Differential Capacity to Prime Immune Responses

Roland Kratzer; François-Xavier Mauvais; Anne Burgevin; Émilie Barilleau; Peter van Endert

J Immunol (2010) 184 (12): 6855–6864.

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Diversity of TCRs on Natural Foxp3⁺ T Cells in Mice Lacking Aire Expression

Danielle Daniely; Joanna Kern; Anna Cebula; Leszek Ignatowicz

J Immunol (2010) 184 (12): 6865–6873.

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Amphioxus SARM Involved in Neural Development May Function as a Suppressor of TLR Signaling

Shaochun Yuan; Kui Wu; Manyi Yang; Liqun Xu; Ling Huang; Huiling Liu; Xin Tao; Shengfeng Huang; Anlong Xu

J Immunol (2010) 184 (12): 6874–6881.

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Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis

Piotr Mydel; Zeneng Wang; Mikael Brisslert; Annelie Hellvard; Leif E. Dahlberg; Stanley L. Hazen; Maria Bokarewa

J Immunol (2010) 184 (12): 6882–6890.

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Meningeal Mast Cells Affect Early T Cell Central Nervous System Infiltration and Blood-Brain Barrier Integrity through TNF: A Role for Neutrophil Recruitment?

Blayne A. Sayed; Alison L. Christy; Margaret E. Walker; Melissa A. Brown

J Immunol (2010) 184 (12): 6891–6900.

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Multiple Mechanisms Downstream of TLR-4 Stimulation Allow Expression of NKG2D Ligands To Facilitate Macrophage/NK Cell Crosstalk

Philipp Eissmann; J. Henry Evans; Maryam Mehrabi; Emma L. Rose; Shlomo Nedvetzki; Daniel M. Davis

J Immunol (2010) 184 (12): 6901–6909.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Structural and Functional Insights of RANKL–RANK Interaction and Signaling

Changzhen Liu; Thomas S. Walter; Peng Huang; Shiqian Zhang; Xuekai Zhu; Ying Wu; Lucy R. Wedderburn; Peifu Tang; Raymond J. Owens; David I. Stuart; Jingshan Ren; Bin Gao

J Immunol (2010) 184 (12): 6910–6919.

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F₁-Adenosine Triphosphatase Displays Properties Characteristic of an Antigen Presentation Molecule for Vγ9Vδ2 T Cells

Jayati Mookerjee-Basu; Pierre Vantourout; Laurent O. Martinez; Bertrand Perret; Xavier Collet; Christian Périgaud; Suzanne Peyrottes; Eric Champagne

J Immunol (2010) 184 (12): 6920–6928.

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The Microtubule Regulator Stathmin Is an Endogenous Protein Agonist for TLR3

Malika Bsibsi; Jeffrey J. Bajramovic; Mario H. J. Vogt; Eveline van Duijvenvoorden; Aabed Baghat; Carla Persoon-Deen; Frans Tielen; Richard Verbeek; Inge Huitinga; Bernhard Ryffel; Alexander Kros; Wouter H. Gerritsen; Sandra Amor; Johannes M. van Noort

J Immunol (2010) 184 (12): 6929–6937.

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The Optimal Antigen Response of Chimeric Antigen Receptors Harboring the CD3ζ Transmembrane Domain Is Dependent upon Incorporation of the Receptor into the Endogenous TCR/CD3 Complex

John S. Bridgeman; Robert E. Hawkins; Steve Bagley; Morgan Blaylock; Mark Holland; David E. Gilham

J Immunol (2010) 184 (12): 6938–6949.

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Evolutionarily Conserved TCR Binding Sites, Identification of T Cells in Primary Lymphoid Tissues, and Surprising Trans-Rearrangements in Nurse Shark

Michael F. Criscitiello; Yuko Ohta; Mark Saltis; E. Churchill McKinney; Martin F. Flajnik

J Immunol (2010) 184 (12): 6950–6960.

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Bam32/DAPP1 Promotes B Cell Adhesion and Formation of Polarized Conjugates with T Cells

Monther Al-Alwan; Sen Hou; Ting-ting Zhang; Kennedy Makondo; Aaron J. Marshall

J Immunol (2010) 184 (12): 6961–6969.

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Transcription-Dependent Mobilization of Nucleosomes at Accessible TCR Gene Segments In Vivo

Hrisavgi D. Kondilis-Mangum; Robin Milley Cobb; Oleg Osipovich; Sruti Srivatsan; Eugene M. Oltz; Michael S. Krangel

J Immunol (2010) 184 (12): 6970–6977.

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Stabilization of an E3 Ligase–E2–Ubiquitin Complex Increases Cell Surface MHC Class I Expression

Lidia M. Duncan; James A. Nathan; Paul J. Lehner

J Immunol (2010) 184 (12): 6978–6985.

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IMMUNOGENETICS

Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements

Scott D. Boyd; Bruno A. Gaëta; Katherine J. Jackson; Andrew Z. Fire; Eleanor L. Marshall; Jason D. Merker; Jay M. Maniar; Lyndon N. Zhang; Bita Sahaf; Carol D. Jones; Birgitte B. Simen; Bozena Hanczaruk; Khoa D. Nguyen; Kari C. Nadeau; Michael Egholm; David B. Miklos; James L. Zehnder; Andrew M. Collins

J Immunol (2010) 184 (12): 6986–6992.

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The Differential Evolutionary Dynamics of Avian Cytokine and TLR Gene Classes

Tim Downing; Andrew T. Lloyd; Cliona O’Farrelly; Daniel G. Bradley

J Immunol (2010) 184 (12): 6993–7000.

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African-Derived Genetic Polymorphisms in TNFAIP3 Mediate Risk for Autoimmunity

James P. Lodolce; Lauren E. Kolodziej; Lesley Rhee; Silvia N. Kariuki; Beverly S. Franek; Nancy M. McGreal; Mark F. Logsdon; Sarah J. Bartulis; Minoli A. Perera; Nathan A. Ellis; Erin J. Adams; Stephen B. Hanauer; Meenakshi Jolly; Timothy B. Niewold; David L. Boone

J Immunol (2010) 184 (12): 7001–7009.

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HOST DEFENSE

Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling

Daniel C. Peltier; Allison Simms; Jocelyn R. Farmer; David J. Miller

J Immunol (2010) 184 (12): 7010–7021.

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TLR9-Dependent Induction of Intestinal α-Defensins by Toxoplasma gondii

David M. Foureau; Daniel W. Mielcarz; Laurence C. Menard; Julie Schulthess; Catherine Werts; Virginie Vasseur; Bernhard Ryffel; Lloyd H. Kasper; Dominique Buzoni-Gatel

J Immunol (2010) 184 (12): 7022–7029.

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HIV-1 Nef Triggers Macrophage Fusion in a p61Hck- and Protease-Dependent Manner

Christel Vérollet; Yan Mei Zhang; Véronique Le Cabec; Julie Mazzolini; Guillaume Charrière; Arnaud Labrousse; Jérôme Bouchet; Indira Medina; Erik Biessen; Florence Niedergang; Serge Bénichou; Isabelle Maridonneau-Parini

J Immunol (2010) 184 (12): 7030–7039.

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P2X₇ Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

Michael P. Lees; Stephen J. Fuller; Rima McLeod; Nicola R. Boulter; Catherine M. Miller; Alana M. Zakrzewski; Ernest J. Mui; William H. Witola; Jessica J. Coyne; Aubrey C. Hargrave; Sarra E. Jamieson; Jenefer M. Blackwell; James S. Wiley; Nicholas C. Smith

J Immunol (2010) 184 (12): 7040–7046.

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Type I IFN Receptor Regulates Neutrophil Functions and Innate Immunity to Leishmania Parasites

Lijun Xin; Diego A. Vargas-Inchaustegui; Sharon S. Raimer; Brent C. Kelly; Jiping Hu; Leiyi Zhu; Jiaren Sun; Lynn Soong

J Immunol (2010) 184 (12): 7047–7056.

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Partial Redundancy of the Pattern Recognition Receptors, Scavenger Receptors, and C-Type Lectins for the Long-Term Control of Mycobacterium tuberculosis Infection

Nathalie Court; Virginie Vasseur; Rachel Vacher; Cécile Frémond; Yury Shebzukhov; Vladimir V. Yeremeev; Isabelle Maillet; Sergei A. Nedospasov; Siamon Gordon; Padraic G. Fallon; Hiroshi Suzuki; Bernhard Ryffel; Valérie F. J. Quesniaux

J Immunol (2010) 184 (12): 7057–7070.

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Phagocytosis and Phagosome Acidification Are Required for Pathogen Processing and MyD88-Dependent Responses to Staphylococcus aureus

W. K. Eddie Ip; Anna Sokolovska; Guillaume M. Charriere; Laurent Boyer; Stephanie Dejardin; Michael P. Cappillino; L. Michael Yantosca; Kazue Takahashi; Kathryn J. Moore; Adam Lacy-Hulbert; Lynda M. Stuart

J Immunol (2010) 184 (12): 7071–7081.

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CD8⁺ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

Santhi Gorantla; Edward Makarov; Jennifer Finke-Dwyer; Catherine L. Gebhart; William Domm; Stephen Dewhurst; Howard E. Gendelman; Larisa Y. Poluektova

J Immunol (2010) 184 (12): 7082–7091.

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Spatiotemporal Regulation of Heat Shock Protein 90-Chaperoned Self-DNA and CpG-Oligodeoxynucleotide for Type I IFN Induction via Targeting to Static Early Endosome

Koichi Okuya; Yasuaki Tamura; Keita Saito; Goro Kutomi; Toshihiko Torigoe; Koichi Hirata; Noriyuki Sato

J Immunol (2010) 184 (12): 7092–7099.

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Essential Role for TLR9 in Prime but Not Prime-Boost Plasmid DNA Vaccination To Activate Dendritic Cells and Protect from Lethal Viral Infection

Diane Rottembourg; Christophe M. Filippi; Damien Bresson; Katrin Ehrhardt; Elizabeth A. Estes; Janine E. Oldham; Matthias G. von Herrath

J Immunol (2010) 184 (12): 7100–7107.

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Human Lung Mast Cells Mediate Pneumococcal Cell Death in Response to Activation by Pneumolysin

Glenn Cruse; Vitor E. Fernandes; Jose de Salort; Depesh Pankhania; Marta S. Marinas; Hannah Brewin; Peter W. Andrew; Peter Bradding; Aras Kadioglu

J Immunol (2010) 184 (12): 7108–7115.

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INFLAMMATION

Identification of Complin, a Novel Complement Inhibitor that Targets Complement Proteins Factor B and C2

Archana P. Kadam; Arvind Sahu

J Immunol (2010) 184 (12): 7116–7124.

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Human Airway Eosinophils Respond to Chemoattractants with Greater Eosinophil-Derived Neurotoxin Release, Adherence to Fibronectin, and Activation of the Ras–ERK Pathway When Compared with Blood Eosinophils

Mary Ellen Bates; Julie B. Sedgwick; Yiming Zhu; Lin Ying Liu; Rose G. Heuser; Nizar N. Jarjour; Hirohito Kita; Paul J. Bertics

J Immunol (2010) 184 (12): 7125–7133.

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Thymic Stromal Lymphopoietin Receptor-Mediated IL-6 and CC/CXC Chemokines Expression in Human Airway Smooth Muscle Cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 Pathways

Lianyu Shan; Naresh Singh Redhu; Ali Saleh; Andrew J. Halayko; Jamila Chakir; Abdelilah S. Gounni

J Immunol (2010) 184 (12): 7134–7143.

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IL-35 Stimulation of CD39⁺ Regulatory T Cells Confers Protection against Collagen II-Induced Arthritis via the Production of IL-10

Irina Kochetkova; Sarah Golden; Kathryn Holderness; Gayle Callis; David W. Pascual

J Immunol (2010) 184 (12): 7144–7153.

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Lupus Serum IgG Induces Skin Inflammation through the TNFR1 Signaling Pathway

Guo-Min Deng; Lena Liu; Vasileios C. Kyttaris; George C. Tsokos

J Immunol (2010) 184 (12): 7154–7161.

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Synoviocyte Innate Immune Responses: II. Pivotal Role of IFN Regulatory Factor 3

Susan E. Sweeney; Trevor B. Kimbler; Gary S. Firestein

J Immunol (2010) 184 (12): 7162–7168.

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Leptin Modulates Innate and Adaptive Immune Cell Recruitment after Cigarette Smoke Exposure in Mice

Juanita H. J. Vernooy; Ken R. Bracke; Nadja E. A. Drummen; Nele S. A. Pauwels; Lennart Zabeau; Robert Jan van Suylen; Jan Tavernier; Guy F. Joos; Emiel F. M. Wouters; Guy G. Brusselle

J Immunol (2010) 184 (12): 7169–7177.

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Small Interfering RNA Screen for Phosphatases Involved in IgE-Mediated Mast Cell Degranulation

Juan Zhang; Mary Mendoza; Michel F. Guiraldelli; Emilia Alina Barbu; Reuben P. Siraganian

J Immunol (2010) 184 (12): 7178–7185.

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Commensal Escherichia coli Reduces Epithelial Apoptosis through IFN-αA–Mediated Induction of Guanylate Binding Protein-1 in Human and Murine Models of Developing Intestine

Julie Mirpuri; Jennifer C. Brazil; Andrew J. Berardinelli; Tala R. Nasr; Kiesha Cooper; Michael Schnoor; Patricia W. Lin; Charles A. Parkos; Nancy A. Louis

J Immunol (2010) 184 (12): 7186–7195.

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α₄β₁ Integrin Mediates the Recruitment of Immature Dendritic Cells across the Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis

Pooja Jain; Caroline Coisne; Gaby Enzmann; Robert Rottapel; Britta Engelhardt

J Immunol (2010) 184 (12): 7196–7206.

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The Prostaglandin E₂ E-Prostanoid 4 Receptor Exerts Anti-Inflammatory Effects in Brain Innate Immunity

Ju Shi; Jenny Johansson; Nathaniel S. Woodling; Qian Wang; Thomas J. Montine; Katrin Andreasson

J Immunol (2010) 184 (12): 7207–7218.

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Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor

Molly M. McFarland-Mancini; Holly M. Funk; Andrew M. Paluch; Mingfu Zhou; Premkumar Vummidi Giridhar; Carol A. Mercer; Sara C. Kozma; Angela F. Drew

J Immunol (2010) 184 (12): 7219–7228.

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CLINICAL IMMUNOLOGY

TLR2 Agonists Enhance CD8⁺Foxp3⁺ Regulatory T Cells and Suppress Th2 Immune Responses during Allergen Immunotherapy

Yi-Giien Tsai; Kuender D. Yang; Dau-Ming Niu; Jien-Wen Chien; Ching-Yuang Lin

J Immunol (2010) 184 (12): 7229–7237.

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Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis

Mario M. Zaiss; Benjamin Frey; Andreas Hess; Jochen Zwerina; Julia Luther; Falk Nimmerjahn; Klaus Engelke; George Kollias; Thomas Hünig; Georg Schett; Jean-Pierre David

J Immunol (2010) 184 (12): 7238–7246.

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The Pathogen Recognition Receptor NOD2 Regulates Human FOXP3⁺ T Cell Survival

Meher K. Rahman; Emilie H. Midtling; Phyllis A. Svingen; Yuning Xiong; Michael P. Bell; Jeanne Tung; Tom Smyrk; Larry J. Egan; William A. Faubion, Jr.

J Immunol (2010) 184 (12): 7247–7256.

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8-Methoxypsoralen Plus Ultraviolet A Therapy Acts via Inhibition of the IL-23/Th17 Axis and Induction of Foxp3⁺ Regulatory T Cells Involving CTLA4 Signaling in a Psoriasis-Like Skin Disorder

Tej Pratap Singh; Michael P. Schön; Katrin Wallbrecht; Kai Michaelis; Beate Rinner; Gerlinde Mayer; Ulrike Schmidbauer; Heimo Strohmaier; Xiao-Jing Wang; Peter Wolf

J Immunol (2010) 184 (12): 7257–7267.

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Cytokine Requirements for the Differentiation and Expansion of IL-17A– and IL-22–Producing Human Vγ2Vδ2 T Cells

Kristin J. Ness-Schwickerath; Chenggang Jin; Craig T. Morita

J Immunol (2010) 184 (12): 7268–7280.

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Timing of CD8⁺ T Cell Responses in Relation to Commencement of Capillary Leakage in Children with Dengue

Nguyen Thi Phuong Dung; Huynh Thi Le Duyen; Nguyen Thi Van Thuy; Tran Van Ngoc; Nguyen Van Vinh Chau; Tran Tinh Hien; Sarah L. Rowland-Jones; Tao Dong; Jeremy Farrar; Bridget Wills; Cameron P. Simmons

J Immunol (2010) 184 (12): 7281–7287.

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Dendritic Cells from Mycobacteria-Infected Mice Inhibits Established Allergic Airway Inflammatory Responses to Ragweed via IL-10– and IL-12–Secreting Mechanisms

Laura Bilenki; Xiaoling Gao; Shuhe Wang; Jie Yang; Yijun Fan; Xiaobing Han; Hongyu Qiu; Xi Yang

J Immunol (2010) 184 (12): 7288–7296.

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Analysis of Complex Biomarkers for Human Immune-Mediated Disorders Based on Cytokine Responsiveness of Peripheral Blood Cells

John M. Davis, III; Keith L. Knutson; Michael A. Strausbauch; Cynthia S. Crowson; Terry M. Therneau; Peter J. Wettstein; Eric L. Matteson; Sherine E. Gabriel

J Immunol (2010) 184 (12): 7297–7304.

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B Cell Receptor-Mediated Calcium Signaling Is Impaired in B Lymphocytes of Type Ia Patients with Common Variable Immunodeficiency

Christian Foerster; Nadine Voelxen; Mirzokhid Rakhmanov; Baerbel Keller; Sylvia Gutenberger; Sigune Goldacker; Jens Thiel; Stefan Feske; Hans-Hartmut Peter; Klaus Warnatz

J Immunol (2010) 184 (12): 7305–7313.

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CORRECTIONS

Correction: Inhibitor Of Nk-κB Kinases α And β Are Both Essential for High Mobility Group Box 1-Mediated Chemotaxis

Marianna Penzo; Raffaella Molteni; Tomomi Suda; Sylvia Samaniego; Angela Raucci; David M. Habiel; Frederick Miller; Hui-ping Jiang; Jun Li; Ruggero Pardi; Roberta Palumbo; Eleonora Olivotto; Richard R. Kew; Marco E. Bianchi; Kenneth B. Marcu

J Immunol (2010) 184 (12): 7314.

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Correction: Persistent γ-Herpesvirus Infection Induces a Cd4 T Cell Response Containing Functionally Distinct Effector Populations

Kathleen A. Stuller; Stephanie S. Cush; Emilio Flaño

J Immunol (2010) 184 (12): 7315.

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Correction: IDO Mediates Tlr9-Driven Protection From Experimental Autoimmune Diabetes

Francesca Fallarino; Claudia Volpi; Teresa Zelante; Carmine Vacca; Mario Calvitti; Maria C. Fioretti; Paolo Puccetti; Luigina Romani; Ursula Grohmann

J Immunol (2010) 184 (12): 7316.

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Cover Image

Cover Image

On the cover: Human airway smooth muscle cells express thymic stromal lymphopoietin receptor subunits. Note the merged colocalization of thymic stromal lymphopoietin receptor (green), IL-7Rα (red), and nuclei (blue) in primary human airway smooth muscle cells. Shan, L., N. S. Redhu, A. Saleh, A. J. Halayko, J. Chakir, A. S. Gounni. 2010. Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38 and JNK) and STAT3 Pathways. J. Immunol. 184: 7134–7143.
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