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Volume 184, Issue 3
1 February 2010
Issue Cover
ISSN 0022-1767
EISSN 1550-6606

IN THIS ISSUE

IN THIS ISSUE
J Immunol (2010) 184 (3): 1125–1126.
View articletitled, IN THIS ISSUE
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PILLARS OF IMMUNOLOGY

Plugging the Leaky Pre-B Cell Receptor
Mary Ellen Conley; Peter D. Burrows
J Immunol (2010) 184 (3): 1127–1129.
View articletitled, Plugging the Leaky Pre-B Cell Receptor
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Pillars Article: A Critical Role of λ5 Protein in B Cell Development. Cell. 1992. 69: 823–831
Daisuke Kitamura; Akira Kudo; Stefan Schaal; Werner Müller; Fritz Melchers; Klaus Rajewsky
J Immunol (2010) 184 (3): 1130–1138.
View articletitled, Pillars Article: A Critical Role of λ5 Protein in B Cell Development. <em>Cell</em>. 1992. 69: 823–831
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CUTTING EDGE

Cutting Edge: Bortezomib-Treated Tumors Sensitized to NK Cell Apoptosis Paradoxically Acquire Resistance to Antigen-Specific T Cells
Andreas Lundqvist; Su Su; Sheila Rao; Richard Childs
J Immunol (2010) 184 (3): 1139–1142.
View articletitled, Cutting Edge: Bortezomib-Treated Tumors Sensitized to NK Cell Apoptosis Paradoxically Acquire Resistance to Antigen-Specific T Cells
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Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3
Sohee Kim; Melanie Prout; Hayley Ramshaw; Angel F. Lopez; Graham LeGros; Booki Min
J Immunol (2010) 184 (3): 1143–1147.
View articletitled, Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3
Supplementary data
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Cutting Edge: Nucleotide-Binding Oligomerization Domain 1-Dependent Responses Account for Murine Resistance against Trypanosoma cruzi Infection
Grace K. Silva; Fredy R. S. Gutierrez; Paulo M. M. Guedes; Catarina V. Horta; Larissa D. Cunha; Tiago W. P. Mineo; Juliana Santiago-Silva; Koichi S. Kobayashi; Richard A. Flavell; João S. Silva; Dario S. Zamboni
J Immunol (2010) 184 (3): 1148–1152.
View articletitled, Cutting Edge: Nucleotide-Binding Oligomerization Domain 1-Dependent Responses Account for Murine Resistance against <em>Trypanosoma cruzi</em> Infection
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Cutting Edge: HLA-DM–Mediated Peptide Exchange Functions Normally on MHC Class II–Peptide Complexes That Have Been Weakened by Elimination of a Conserved Hydrogen Bond
Andrea Ferrante; Jack Gorski
J Immunol (2010) 184 (3): 1153–1158.
View articletitled, Cutting Edge: HLA-DM–Mediated Peptide Exchange Functions Normally on MHC Class II–Peptide Complexes That Have Been Weakened by Elimination of a Conserved Hydrogen Bond
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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Human Plasmacytoid Dendritic Cells Support Th17 Cell Effector Function in Response to TLR7 Ligation
Chun-Feng Yu; Wen-Ming Peng; Johannes Oldenburg; Jochen Hoch; Thomas Bieber; Andreas Limmer; Gunther Hartmann; Winfried Barchet; Anna Maria Eis-Hübinger; Natalija Novak
J Immunol (2010) 184 (3): 1159–1167.
View articletitled, Human Plasmacytoid Dendritic Cells Support Th17 Cell Effector Function in Response to TLR7 Ligation
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Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein
Nadege Goutagny; Zhaozhao Jiang; Jane Tian; Peggy Parroche; Jeanne Schickli; Brian G. Monks; Nancy Ulbrandt; Hong Ji; Peter A. Kiener; Anthony J. Coyle; Katherine A. Fitzgerald
J Immunol (2010) 184 (3): 1168–1179.
View articletitled, Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein
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SHP-1 Deficient Mast Cells Are Hyperresponsive to Stimulation and Critical in Initiating Allergic Inflammation in the Lung
Li Zhang; Sun Young Oh; Xinxing Wu; Min Hee Oh; Fan Wu; John T. Schroeder; Clifford M. Takemoto; Tao Zheng; Zhou Zhu
J Immunol (2010) 184 (3): 1180–1190.
View articletitled, SHP-1 Deficient Mast Cells Are Hyperresponsive to Stimulation and Critical in Initiating Allergic Inflammation in the Lung
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Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells
Dong-Mei Zhao; Shuyang Yu; Xinyuan Zhou; Jodie S. Haring; Werner Held; Vladimir P. Badovinac; John T. Harty; Hai-Hui Xue
J Immunol (2010) 184 (3): 1191–1199.
View articletitled, Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells
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Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes
Katrin Dietl; Kathrin Renner; Katja Dettmer; Birgit Timischl; Karin Eberhart; Christoph Dorn; Claus Hellerbrand; Michael Kastenberger; Leoni A. Kunz-Schughart; Peter J. Oefner; Reinhard Andreesen; Eva Gottfried; Marina P. Kreutz
J Immunol (2010) 184 (3): 1200–1209.
View articletitled, Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes
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A Recombinant Bispecific Single-Chain Fragment Variable Specific for HLA Class II and FcαRI (CD89) Recruits Polymorphonuclear Neutrophils for Efficient Lysis of Malignant B Lymphoid Cells
Yvonne Guettinger; Karin Barbin; Matthias Peipp; Joerg Bruenke; Michael Dechant; Heike Horner; Doreen Thierschmidt; Thomas Valerius; Roland Repp; Georg H. Fey; Bernhard Stockmeyer
J Immunol (2010) 184 (3): 1210–1217.
View articletitled, A Recombinant Bispecific Single-Chain Fragment Variable Specific for HLA Class II and FcαRI (CD89) Recruits Polymorphonuclear Neutrophils for Efficient Lysis of Malignant B Lymphoid Cells
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Commensal Microbiota and CD8+ T Cells Shape the Formation of Invariant NKT Cells
Bo Wei; Gerhard Wingender; Daisuke Fujiwara; Diana YuHui Chen; Michael McPherson; Sarah Brewer; James Borneman; Mitchell Kronenberg; Jonathan Braun
J Immunol (2010) 184 (3): 1218–1226.
View articletitled, Commensal Microbiota and CD8<sup>+</sup> T Cells Shape the Formation of Invariant NKT Cells
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B Cells Delay Neutrophil Migration toward the Site of Stimulus: Tardiness Critical for Effective Bacillus Calmette-Guérin Vaccination against Tuberculosis Infection in Mice
Tatiana K. Kondratieva; Elvira I. Rubakova; Irina A. Linge; Vladimir V. Evstifeev; Konstantin B. Majorov; Alexander S. Apt
J Immunol (2010) 184 (3): 1227–1234.
View articletitled, B Cells Delay Neutrophil Migration toward the Site of Stimulus: Tardiness Critical for Effective Bacillus Calmette-Guérin Vaccination against Tuberculosis Infection in Mice
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Early Recycling Compartment Trafficking of CD1a Is Essential for Its Intersection and Presentation of Lipid Antigens
Manuela Cernadas; Marco Cavallari; Gerald Watts; Lucia Mori; Gennaro De Libero; Michael B. Brenner
J Immunol (2010) 184 (3): 1235–1241.
View articletitled, Early Recycling Compartment Trafficking of CD1a Is Essential for Its Intersection and Presentation of Lipid Antigens
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Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-γ Production
Stephen R. Mattarollo; Azad Rahimpour; Allison Choyce; Dale I. Godfrey; Graham R. Leggatt; Ian H. Frazer
J Immunol (2010) 184 (3): 1242–1250.
View articletitled, Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-γ Production
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Progenitor Cell Origin Plays a Role in Fate Choices of Mature B Cells
Valentina Fossati; Ritu Kumar; Hans-Willem Snoeck
J Immunol (2010) 184 (3): 1251–1260.
View articletitled, Progenitor Cell Origin Plays a Role in Fate Choices of Mature B Cells
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Recruitment and Differentiation of Conventional Dendritic Cell Precursors in Tumors
Jun Diao; Jun Zhao; Erin Winter; Mark S. Cattral
J Immunol (2010) 184 (3): 1261–1267.
View articletitled, Recruitment and Differentiation of Conventional Dendritic Cell Precursors in Tumors
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Development of Promyelocytic Zinc Finger and ThPOK-Expressing Innate γδ T Cells Is Controlled by Strength of TCR Signaling and Id3
Eric S. Alonzo; Rachel A. Gottschalk; Joy Das; Takeshi Egawa; Robin M. Hobbs; Pier Paolo Pandolfi; Pablo Pereira; Kim E. Nichols; Gary A. Koretzky; Martha S. Jordan; Derek B. Sant’Angelo
J Immunol (2010) 184 (3): 1268–1279.
View articletitled, Development of Promyelocytic Zinc Finger and ThPOK-Expressing Innate γδ T Cells Is Controlled by Strength of TCR Signaling and Id3
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TLR4-Mediated Podosome Loss Discriminates Gram-Negative from Gram-Positive Bacteria in Their Capacity to Induce Dendritic Cell Migration and Maturation
Suzanne F. G. van Helden; Koen van den Dries; Machteld M. Oud; Reinier A. P. Raymakers; Mihai G. Netea; Frank N. van Leeuwen; Carl G. Figdor
J Immunol (2010) 184 (3): 1280–1291.
View articletitled, TLR4-Mediated Podosome Loss Discriminates Gram-Negative from Gram-Positive Bacteria in Their Capacity to Induce Dendritic Cell Migration and Maturation
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Loss of CD34 Leads To Exacerbated Autoimmune Arthritis through Increased Vascular Permeability
Marie-Renée Blanchet; Matthew Gold; Steven Maltby; Jami Bennett; Björn Petri; Paul Kubes; David M. Lee; Kelly M. McNagny
J Immunol (2010) 184 (3): 1292–1299.
View articletitled, Loss of CD34 Leads To Exacerbated Autoimmune Arthritis through Increased Vascular Permeability
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Human Embryonic Stem Cells Suppress T Cell Responses via Arginase I-Dependent Mechanism
Nurit Yachimovich-Cohen; Sharona Even-Ram; Yoel Shufaro; Jacob Rachmilewitz; Benjamin Reubinoff
J Immunol (2010) 184 (3): 1300–1308.
View articletitled, Human Embryonic Stem Cells Suppress T Cell Responses via Arginase I-Dependent Mechanism
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Phylogenetic and Functional Analysis Identifies Ets-1 as a Novel Regulator of the Th2 Cytokine Gene Locus
Jannine M. Strempel; Roland Grenningloh; I-Cheng Ho; Donata Vercelli
J Immunol (2010) 184 (3): 1309–1316.
View articletitled, Phylogenetic and Functional Analysis Identifies Ets-1 as a Novel Regulator of the Th2 Cytokine Gene Locus
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T Cell–Dendritic Cell Interaction Dynamics during the Induction of Respiratory Tolerance and Immunity
Nadja Bakočević; Tim Worbs; Ana Davalos-Misslitz; Reinhold Förster
J Immunol (2010) 184 (3): 1317–1327.
View articletitled, T Cell–Dendritic Cell Interaction Dynamics during the Induction of Respiratory Tolerance and Immunity
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Formation of a Mast Cell Synapse: FcεRI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on Surfaces
Amanda Carroll-Portillo; Kathrin Spendier; Janet Pfeiffer; Gary Griffiths; Haitao Li; Keith A. Lidke; Janet M. Oliver; Diane S. Lidke; James L. Thomas; Bridget S. Wilson; Jerilyn A. Timlin
J Immunol (2010) 184 (3): 1328–1338.
View articletitled, Formation of a Mast Cell Synapse: FcεRI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on Surfaces
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Broad Volume Distributions Indicate Nonsynchronized Growth and Suggest Sudden Collapses of Germinal Center B Cell Populations
Nicole Wittenbrink; Tom S. Weber; Anke Klein; Armin A. Weiser; Werner Zuschratter; Michael Sibila; Johannes Schuchhardt; Michal Or-Guil
J Immunol (2010) 184 (3): 1339–1347.
View articletitled, Broad Volume Distributions Indicate Nonsynchronized Growth and Suggest Sudden Collapses of Germinal Center B Cell Populations
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Autoimmune Disease in Lyn-Deficient Mice Is Dependent on an Inflammatory Environment Established by IL-6
Evelyn Tsantikos; Sarah A. Oracki; Cathy Quilici; Gary P. Anderson; David M. Tarlinton; Margaret L. Hibbs
J Immunol (2010) 184 (3): 1348–1360.
View articletitled, Autoimmune Disease in Lyn-Deficient Mice Is Dependent on an Inflammatory Environment Established by IL-6
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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Structural Basis for the Blockage of IL-2 Signaling by Therapeutic Antibody Basiliximab
Jiamu Du; Hui Yang; Dapeng Zhang; Jianchuan Wang; Huaizu Guo; Baozhen Peng; Yajun Guo; Jianping Ding
J Immunol (2010) 184 (3): 1361–1368.
View articletitled, Structural Basis for the Blockage of IL-2 Signaling by Therapeutic Antibody Basiliximab
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TCRβ Feedback Signals Inhibit the Coupling of Recombinationally Accessible Vβ14 Segments with DJβ Complexes
Katherine S. Yang-Iott; Andrea C. Carpenter; Marta A. W. Rowh; Natalie Steinel; Brenna L. Brady; Konrad Hochedlinger; Rudolf Jaenisch; Craig H. Bassing
J Immunol (2010) 184 (3): 1369–1378.
View articletitled, TCRβ Feedback Signals Inhibit the Coupling of Recombinationally Accessible Vβ14 Segments with DJβ Complexes
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IMMUNOGENETICS

A Small, Variable, and Irregular Killer Cell Ig-Like Receptor Locus Accompanies the Absence of MHC-C and MHC-G in Gibbons
Laurent Abi-Rached; Heiner Kuhl; Christian Roos; Boudewijn ten Hallers; Baoli Zhu; Lucia Carbone; Pieter J. de Jong; Alan R. Mootnick; Florian Knaust; Richard Reinhardt; Peter Parham; Lutz Walter
J Immunol (2010) 184 (3): 1379–1391.
View articletitled, A Small, Variable, and Irregular Killer Cell Ig-Like Receptor Locus Accompanies the Absence of <em>MHC-C</em> and <em>MHC-G</em> in Gibbons
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HOST DEFENSE

IL-10 Induction by Bordetella parapertussis Limits a Protective IFN-γ Response
Daniel N. Wolfe; Alexia T. Karanikas; Sara E. Hester; Mary J. Kennett; Eric T. Harvill
J Immunol (2010) 184 (3): 1392–1400.
View articletitled, IL-10 Induction by <em>Bordetella parapertussis</em> Limits a Protective IFN-γ Response
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IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis
Shigeaki Inoue; Jacqueline Unsinger; Christopher G. Davis; Jared T. Muenzer; Thomas A. Ferguson; Katherine Chang; Dale F. Osborne; Andrew T. Clark; Craig M. Coopersmith; Jonathan E. McDunn; Richard S. Hotchkiss
J Immunol (2010) 184 (3): 1401–1409.
View articletitled, IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis
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Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia
Masafumi Seki; Shigeru Kohno; Michael W. Newstead; Xianying Zeng; Urvashi Bhan; Nicholas W. Lukacs; Steven L. Kunkel; Theodore J. Standiford
J Immunol (2010) 184 (3): 1410–1418.
View articletitled, Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia
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Defective Ribosomal Products Are the Major Source of Antigenic Peptides Endogenously Generated from Influenza A Virus Neuraminidase
Brian P. Dolan; Lily Li; Kazuyo Takeda; Jack R. Bennink; Jonathan W. Yewdell
J Immunol (2010) 184 (3): 1419–1424.
View articletitled, Defective Ribosomal Products Are the Major Source of Antigenic Peptides Endogenously Generated from Influenza A Virus Neuraminidase
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LL-37 Promotes Rapid Sensing of CpG Oligodeoxynucleotides by B Lymphocytes and Plasmacytoid Dendritic Cells
Plinio Hurtado; Chen Au Peh
J Immunol (2010) 184 (3): 1425–1435.
View articletitled, LL-37 Promotes Rapid Sensing of CpG Oligodeoxynucleotides by B Lymphocytes and Plasmacytoid Dendritic Cells
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Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events
Sheerazed Boulkroun; Laure Guenin-Macé; Maria-Isabel Thoulouze; Marc Monot; Anaïs Merckx; Gordon Langsley; Georges Bismuth; Vincenzo Di Bartolo; Caroline Demangel
J Immunol (2010) 184 (3): 1436–1444.
View articletitled, Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events
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Critical Protective Role for MCP-1 in Pneumonic Burkholderia mallei Infection
Andrew Goodyear; Abby Jones; Ryan Troyer; Helle Bielefeldt-Ohmann; Steven Dow
J Immunol (2010) 184 (3): 1445–1454.
View articletitled, Critical Protective Role for MCP-1 in Pneumonic <em>Burkholderia mallei</em> Infection
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TLR2-Dependent Inflammatory Response to Porphyromonas gingivalis Is MyD88 Independent, whereas MyD88 Is Required To Clear Infection
Elia Burns; Tal Eliyahu; Satoshi Uematsu; Shizuo Akira; Gabriel Nussbaum
J Immunol (2010) 184 (3): 1455–1462.
View articletitled, TLR2-Dependent Inflammatory Response to <em>Porphyromonas gingivalis</em> Is MyD88 Independent, whereas MyD88 Is Required To Clear Infection
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INFLAMMATION

Regulation of FcεRI Expression during Murine Basophil Maturation: The Interplay between IgE, Cell Division, and FcεRI Synthetic Rate
Asifa K. Zaidi; Donald W. MacGlashan
J Immunol (2010) 184 (3): 1463–1474.
View articletitled, Regulation of FcεRI Expression during Murine Basophil Maturation: The Interplay between IgE, Cell Division, and FcεRI Synthetic Rate
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Inhibitory Role of Sphingosine 1-Phosphate Receptor 2 in Macrophage Recruitment during Inflammation
Jason Michaud; Dong-Soon Im; Timothy Hla
J Immunol (2010) 184 (3): 1475–1483.
View articletitled, Inhibitory Role of Sphingosine 1-Phosphate Receptor 2 in Macrophage Recruitment during Inflammation
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IL-17 Regulates CXCL1 mRNA Stability via an AUUUA/Tristetraprolin-Independent Sequence
Shyamasree Datta; Michael Novotny; Paul G. Pavicic, Jr.; Chenyang Zhao; Tomasz Herjan; Justin Hartupee; Thomas Hamilton
J Immunol (2010) 184 (3): 1484–1491.
View articletitled, IL-17 Regulates CXCL1 mRNA Stability via an AUUUA/Tristetraprolin-Independent Sequence
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The Alarmin Cytokine, High Mobility Group Box 1, Is Produced by Viable Cardiomyocytes and Mediates the Lipopolysaccharide-Induced Myocardial Dysfunction via a TLR4/Phosphatidylinositol 3-Kinase γ Pathway
Hu Xu; Zhaoliang Su; Jun Wu; Min Yang; Josef M. Penninger; Claudio M. Martin; Peter R. Kvietys; Tao Rui
J Immunol (2010) 184 (3): 1492–1498.
View articletitled, The Alarmin Cytokine, High Mobility Group Box 1, Is Produced by Viable Cardiomyocytes and Mediates the Lipopolysaccharide-Induced Myocardial Dysfunction via a TLR4/Phosphatidylinositol 3-Kinase γ Pathway
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Roles of Sema4D–Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis
Tatsusada Okuno; Yuji Nakatsuji; Masayuki Moriya; Hyota Takamatsu; Satoshi Nojima; Noriko Takegahara; Toshihiko Toyofuku; Yukinobu Nakagawa; Sujin Kang; Roland H. Friedel; Saburo Sakoda; Hitoshi Kikutani; Atsushi Kumanogoh
J Immunol (2010) 184 (3): 1499–1506.
View articletitled, Roles of Sema4D–Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis
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Diabetes-Induced Oxidative Stress Is Mediated by Ca2+-Independent Phospholipase A2 in Neutrophils
Srinivas Ayilavarapu; Alpdogan Kantarci; Gabrielle Fredman; Oya Turkoglu; Kazuhiro Omori; Hongsheng Liu; Tomoyuki Iwata; Motohiko Yagi; Hatice Hasturk; Thomas E. Van Dyke
J Immunol (2010) 184 (3): 1507–1515.
View articletitled, Diabetes-Induced Oxidative Stress Is Mediated by Ca<sup>2+</sup>-Independent Phospholipase A2 in Neutrophils
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A New Strategy for the Identification of Novel Molecules with Targeted Proresolution of Inflammation Properties
Roberta A. Navarro-Xavier; Justine Newson; Vera Lucia Flor Silveira; Stuart N. Farrow; Derek W. Gilroy; Jonas Bystrom
J Immunol (2010) 184 (3): 1516–1525.
View articletitled, A New Strategy for the Identification of Novel Molecules with Targeted Proresolution of Inflammation Properties
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IL-33 Induces IL-13–Dependent Cutaneous Fibrosis
Andrew L. Rankin; John B. Mumm; Erin Murphy; Scott Turner; Ni Yu; Terrill K. McClanahan; Patricia A. Bourne; Robert H. Pierce; Rob Kastelein; Stefan Pflanz
J Immunol (2010) 184 (3): 1526–1535.
View articletitled, IL-33 Induces IL-13–Dependent Cutaneous Fibrosis
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Stromal Interaction Molecules 1 and 2 Are Key Regulators of Autoreactive T Cell Activation in Murine Autoimmune Central Nervous System Inflammation
Michael K. Schuhmann; David Stegner; Alejandro Berna-Erro; Stefan Bittner; Attila Braun; Christoph Kleinschnitz; Guido Stoll; Heinz Wiendl; Sven G. Meuth; Bernhard Nieswandt
J Immunol (2010) 184 (3): 1536–1542.
View articletitled, Stromal Interaction Molecules 1 and 2 Are Key Regulators of Autoreactive T Cell Activation in Murine Autoimmune Central Nervous System Inflammation
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Essential Roles of IL-6 Trans-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble–IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model
Satoshi Matsumoto; Taeko Hara; Keiichi Mitsuyama; Mayuko Yamamoto; Osamu Tsuruta; Michio Sata; Jürgen Scheller; Stefan Rose-John; Sho-ichi Kado; Toshihiko Takada
J Immunol (2010) 184 (3): 1543–1551.
View articletitled, Essential Roles of IL-6 <em>Trans</em>-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble–IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model
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IFN-γ Regulates the Requirement for IL-17 in Proteoglycan-Induced Arthritis
Paul D. Doodes; Yanxia Cao; Keith M. Hamel; Yumei Wang; Rachel L. Rodeghero; Katalin Mikecz; Tibor T. Glant; Yoichiro Iwakura; Alison Finnegan
J Immunol (2010) 184 (3): 1552–1559.
View articletitled, IFN-γ Regulates the Requirement for IL-17 in Proteoglycan-Induced Arthritis
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Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF-α
Akira Hashiramoto; Takashi Yamane; Ken Tsumiyama; Kohsuke Yoshida; Koichiro Komai; Hiroyuki Yamada; Fumiyoshi Yamazaki; Masao Doi; Hitoshi Okamura; Shunichi Shiozawa
J Immunol (2010) 184 (3): 1560–1565.
View articletitled, Mammalian <em>Clock</em> Gene <em>Cryptochrome</em> Regulates Arthritis via Proinflammatory Cytokine TNF-α
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Regulation of Lentivirus Neurovirulence by Lipopolysaccharide Conditioning: Suppression of CXCL10 in the Brain by IL-10
Ferdinand Maingat; Serena Viappiani; Yu Zhu; Pornpun Vivithanaporn; Kristofor K. Ellestad; Janet Holden; Claudia Silva; Christopher Power
J Immunol (2010) 184 (3): 1566–1574.
View articletitled, Regulation of Lentivirus Neurovirulence by Lipopolysaccharide Conditioning: Suppression of CXCL10 in the Brain by IL-10
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Matrix Metalloproteinase-8 Inactivates Macrophage Inflammatory Protein-1α To Reduce Acute Lung Inflammation and Injury in Mice
Pablo A. Quintero; Martin D. Knolle; Luisa F. Cala; Yuehong Zhuang; Caroline A. Owen
J Immunol (2010) 184 (3): 1575–1588.
View articletitled, Matrix Metalloproteinase-8 Inactivates Macrophage Inflammatory Protein-1α To Reduce Acute Lung Inflammation and Injury in Mice
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CLINICAL IMMUNOLOGY

Promoting Immune Responses by LIGHT in the Face of Abundant Regulatory T Cell Inhibition
Yugang Wang; Mingzhao Zhu; Ping Yu; Yang-Xin Fu
J Immunol (2010) 184 (3): 1589–1595.
View articletitled, Promoting Immune Responses by LIGHT in the Face of Abundant Regulatory T Cell Inhibition
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T Cells Are Required for the Production of Blister-Inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita
Ana Gabriela Sitaru; Alina Sesarman; Sidonia Mihai; Mircea T. Chiriac; Detlef Zillikens; Per Hultman; Werner Solbach; Cassian Sitaru
J Immunol (2010) 184 (3): 1596–1603.
View articletitled, T Cells Are Required for the Production of Blister-Inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita
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Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection
Annie Gosselin; Patricia Monteiro; Nicolas Chomont; Felipe Diaz-Griffero; Elias A. Said; Simone Fonseca; Vanessa Wacleche; Mohamed El-Far; Mohamed-Rachid Boulassel; Jean-Pierre Routy; Rafick-Pierre Sekaly; Petronela Ancuta
J Immunol (2010) 184 (3): 1604–1616.
View articletitled, Peripheral Blood CCR4<sup>+</sup>CCR6<sup>+</sup> and CXCR3<sup>+</sup>CCR6<sup>+</sup> CD4<sup>+</sup> T Cells Are Highly Permissive to HIV-1 Infection
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A Single TCRα-Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire
Xiaoling Liang; Luise U. Weigand; Ingrid G. Schuster; Elfriede Eppinger; Judith C. van der Griendt; Andrea Schub; Matthias Leisegang; Daniel Sommermeyer; Florian Anderl; Yanyan Han; Joachim Ellwart; Andreas Moosmann; Dirk H. Busch; Wolfgang Uckert; Christian Peschel; Angela M. Krackhardt
J Immunol (2010) 184 (3): 1617–1629.
View articletitled, A Single TCRα-Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire
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Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells
Xinming Su; Jian Ye; Eddy C. Hsueh; Yanping Zhang; Daniel F. Hoft; Guangyong Peng
J Immunol (2010) 184 (3): 1630–1641.
View articletitled, Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells
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IL-8 Dictates Glycosaminoglycan Binding and Stability of IL-18 in Cystic Fibrosis
Emer P. Reeves; Michael Williamson; Barry Byrne; David A. Bergin; Stephen G. J. Smith; Peter Greally; Richard O’Kennedy; Shane J. O’Neill; Noel G. McElvaney
J Immunol (2010) 184 (3): 1642–1652.
View articletitled, IL-8 Dictates Glycosaminoglycan Binding and Stability of IL-18 in Cystic Fibrosis
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CORRECTIONS

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression
Torsten Juelich; Elissa Sutcliffe; Alice Denton; Yiqing He; Peter C. Doherty; Christopher Parish; Steven J. Turner; David Tremethick; Sudha Rao
J Immunol (2010) 184 (3): 1653.
View articletitled, Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression
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IL-4Rα, a new member that associates with Syk kinase: implication in IL-4-induced human neutrophil functions
Jamila Ennaciri; Denis Girard
J Immunol (2010) 184 (3): 1654.
View articletitled, IL-4Rα, a new member that associates with Syk kinase: implication in IL-4-induced human neutrophil functions
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Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production
Caroline R. Boyd; Selinda J. Orr; Shaun Spence; James F. Burrows; Joanne Elliott; Helen P. Carroll; Kiva Brennan; Joan Ní Gabhann; Wilson A. Coulter; James A. Johnston; Caroline A. Jefferies
J Immunol (2010) 184 (3): 1655.
View articletitled, Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production
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Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis
Qunzhou Zhang; Shihong Shi; Yi Liu; Jettie Uyanne; Yufang Shi; Songtao Shi; Anh D. Le
J Immunol (2010) 184 (3): 1656.
View articletitled, Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis
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