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Issues
1 March 2010
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
Pillars Article: CD19: Lowering the Threshold for Antigen Receptor Stimulation of B Lymphocytes. Science, 1992. 256: 105–107
J Immunol (2010) 184 (5): 2233–2235.
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling
Philip O. Scumpia; Kindra M. Kelly-Scumpia; Matthew J. Delano; Jason S. Weinstein; Alex G. Cuenca; Samer Al-Quran; Ian Bovio; Shizuo Akira; Yutaro Kumagai; Lyle L. Moldawer
J Immunol (2010) 184 (5): 2247–2251.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Distinct Phenotype and Function of NK Cells in the Pancreas of Nonobese Diabetic Mice
Hanna Brauner; Marjet Elemans; Sara Lemos; Christian Broberger; Dan Holmberg; Malin Flodström-Tullberg; Klas Kärre; Petter Höglund
J Immunol (2010) 184 (5): 2272–2280.
IL-17 Promotes Tumor Development through the Induction of Tumor Promoting Microenvironments at Tumor Sites and Myeloid-Derived Suppressor Cells
J Immunol (2010) 184 (5): 2281–2288.
Nod1 and Nod2 Are Expressed in Human and Murine Renal Tubular Epithelial Cells and Participate in Renal Ischemia Reperfusion Injury
Alana A. Shigeoka; Amanpreet Kambo; John C. Mathison; Andrew J. King; Wesley F. Hall; Jean da Silva Correia; Richard J. Ulevitch; Dianne B. McKay
J Immunol (2010) 184 (5): 2297–2304.
The Single IgG IL-1–Related Receptor Controls TLR Responses in Differentiated Human Intestinal Epithelial Cells
Mohammed A. Khan; Theodore S. Steiner; Ho Pan Sham; Kirk S. Bergstrom; Jingtian T. Huang; Kiran Assi; Bill Salh; Isabella T. Tai; Xiaoxia Li; Bruce A. Vallance
J Immunol (2010) 184 (5): 2305–2313.
Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression
Guangwen Ren; Xin Zhao; Liying Zhang; Jimin Zhang; Andrew L'Huillier; Weifang Ling; Arthur I. Roberts; Anh D. Le; Songtao Shi; Changshun Shao; Yufang Shi
J Immunol (2010) 184 (5): 2321–2328.
NK Cell Patrolling and Elimination of Donor-Derived Dendritic Cells Favor Indirect Alloreactivity
J Immunol (2010) 184 (5): 2329–2336.
Anti-Programmed Cell Death 1 Antibody Reduces CD4+PD-1+ T Cells and Relieves the Lupus-Like Nephritis of NZB/W F1 Mice
Shimpei Kasagi; Seiji Kawano; Taku Okazaki; Tasuku Honjo; Akio Morinobu; Saori Hatachi; Kenichiro Shimatani; Yoshimasa Tanaka; Nagahiro Minato; Shunichi Kumagai
J Immunol (2010) 184 (5): 2337–2347.
IL-12 and IL-27 Sequential Gene Therapy via Intramuscular Electroporation Delivery for Eliminating Distal Aggressive Tumors
J Immunol (2010) 184 (5): 2348–2354.
Evolution of Recognition of Ligands from Gram-Positive Bacteria: Similarities and Differences in the TLR2-Mediated Response between Mammalian Vertebrates and Teleost Fish
Carla M. S. Ribeiro; Trudi Hermsen; Anja J. Taverne-Thiele; Huub F. J. Savelkoul; Geert F. Wiegertjes
J Immunol (2010) 184 (5): 2355–2368.
MicroRNA Regulation of IFN-β Protein Expression: Rapid and Sensitive Modulation of the Innate Immune Response
J Immunol (2010) 184 (5): 2369–2376.
Transient Receptor Potential Melastatin 2 Is Required for Lipopolysaccharide-Induced Cytokine Production in Human Monocytes
J Immunol (2010) 184 (5): 2386–2393.
Intracellular MHC Class II Controls Regulatory Tolerance to Allogeneic Transplants
Christian LeGuern; Yoshinobu Akiyama; Sharon Germana; Katsunori Tanaka; Luis Fernandez; Yoshiko Iwamoto; Stuart Houser; Gilles Benichou
J Immunol (2010) 184 (5): 2394–2400.
Stimulation of Naive CD8+ T Cells by a Variant Viral Epitope Induces Activation and Enhanced Apoptosis
J Immunol (2010) 184 (5): 2401–2409.
Transient CD86 Expression on Hepatitis C Virus-Specific CD8+ T Cells in Acute Infection Is Linked to Sufficient IL-2 Signaling
Henry Radziewicz; Chris C. Ibegbu; Huiming Hon; Nathalie Bédard; Julie Bruneau; Kimberly A. Workowski; Stuart J. Knechtle; Allan D. Kirk; Christian P. Larsen; Naglaa H. Shoukry; Arash Grakoui
J Immunol (2010) 184 (5): 2410–2422.
Distinct Protease Requirements for Antigen Presentation In Vitro and In Vivo
J Immunol (2010) 184 (5): 2423–2431.
Receptor Activator of NF-κB (RANK) Ligand Induces Ectodomain Shedding of RANK in Murine RAW264.7 Macrophages
Akihiro Hakozaki; Masaki Yoda; Takahide Tohmonda; Mitsuru Furukawa; Tomohiro Hikata; Shinichi Uchikawa; Hironari Takaishi; Morio Matsumoto; Kazuhiro Chiba; Keisuke Horiuchi; Yoshiaki Toyama
J Immunol (2010) 184 (5): 2442–2448.
Improving Survival Rates in Two Models of Spontaneous Postoperative Metastasis in Mice by Combined Administration of a β-Adrenergic Antagonist and a Cyclooxygenase-2 Inhibitor
Ariella Glasner; Roi Avraham; Ella Rosenne; Marganit Benish; Oded Zmora; Shaily Shemer; Hadas Meiboom; Shamgar Ben-Eliyahu
J Immunol (2010) 184 (5): 2449–2457.
Control of α4β7 Integrin Expression and CD4 T Cell Homing by the β1 Integrin Subunit
J Immunol (2010) 184 (5): 2458–2467.
CD72 Negatively Regulates KIT-Mediated Responses in Human Mast Cells
J Immunol (2010) 184 (5): 2468–2475.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
The Role of the LAT–PLC-γ1 Interaction in T Regulatory Cell Function
J Immunol (2010) 184 (5): 2476–2486.
Activation-Induced Cytidine Deaminase Splice Variants Are Defective Because of the Lack of Structural Support for the Catalytic Site
J Immunol (2010) 184 (5): 2487–2491.
Five HLA-DP Molecules Frequently Expressed in the Worldwide Human Population Share a Common HLA Supertypic Binding Specificity
J Immunol (2010) 184 (5): 2492–2503.
Structural Basis for Lipid-Antigen Recognition in Avian Immunity
J Immunol (2010) 184 (5): 2504–2511.
IMMUNOGENETICS
HOST DEFENSE
Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response
Alexander Panda; Feng Qian; Subhasis Mohanty; David van Duin; Frances K. Newman; Lin Zhang; Shu Chen; Virginia Towle; Robert B. Belshe; Erol Fikrig; Heather G. Allore; Ruth R. Montgomery; Albert C. Shaw
J Immunol (2010) 184 (5): 2518–2527.
Differential Effector Pathways Regulate Memory CD8 T Cell Immunity against Plasmodium berghei versus P. yoelii Sporozoites
J Immunol (2010) 184 (5): 2528–2538.
Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment
Anastasia Nijnik; Laurence Madera; Shuhua Ma; Matthew Waldbrook; Melissa R. Elliott; Donna M. Easton; Matthew L. Mayer; Sarah C. Mullaly; Jason Kindrachuk; Håvard Jenssen; Robert E. W. Hancock
J Immunol (2010) 184 (5): 2539–2550.
Stimulator of IFN Gene Is Critical for Induction of IFN-β during Chlamydia muridarum Infection
J Immunol (2010) 184 (5): 2551–2560.
A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8+ T Cell Epitope-Based Vaccines against Ocular Herpes
Aziz A. Chentoufi; Gargi Dasgupta; Neil D. Christensen; Jiafen Hu; Zareen S. Choudhury; Arfan Azeem; James V. Jester; Anthony B. Nesburn; Steven L. Wechsler; Lbachir BenMohamed
J Immunol (2010) 184 (5): 2561–2571.
Arginase II Restricts Host Defense to Helicobacter pylori by Attenuating Inducible Nitric Oxide Synthase Translation in Macrophages
Nuruddeen D. Lewis; Mohammad Asim; Daniel P. Barry; Kshipra Singh; Thibaut de Sablet; Jean-Luc Boucher; Alain P. Gobert; Rupesh Chaturvedi; Keith T. Wilson
J Immunol (2010) 184 (5): 2572–2582.
Therapeutic Glucocorticoid-Induced TNF Receptor-Mediated Amplification of CD4+ T Cell Responses Enhances Antiparasitic Immunity
Ashraful Haque; Amanda C. Stanley; Fiona H. Amante; Fabian de Labastida Rivera; YongHong Zhou; Rachel D. Kuns; Vanessa Yardley; Shimon Sakaguchi; Geoffrey R. Hill; Christian R. Engwerda
J Immunol (2010) 184 (5): 2583–2592.
INFLAMMATION
NFAT1 Mediates Placental Growth Factor-Induced Myelomonocytic Cell Recruitment via the Induction of TNF-α
Yanping Ding; Yujie Huang; Nan Song; Xiaobin Gao; Shaopeng Yuan; Xiaofeng Wang; Hongchen Cai; Yan Fu; Yongzhang Luo
J Immunol (2010) 184 (5): 2593–2601.
Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation
Neil Dufton; Robert Hannon; Vincenzo Brancaleone; Jesmond Dalli; Hetal B. Patel; Mohini Gray; Fulvio D’Acquisto; Julia C. Buckingham; Mauro Perretti; Roderick J. Flower
J Immunol (2010) 184 (5): 2611–2619.
IL-33 Exacerbates Autoantibody-Induced Arthritis
Damo Xu; Hui-Rong Jiang; Yubin Li; Peter N. Pushparaj; Mariola Kurowska-Stolarska; Bernard P. Leung; Rong Mu; Hwee Kee Tay; Andrew N. J. McKenzie; Iain B. McInnes; Alirio J. Melendez; Foo Y. Liew
J Immunol (2010) 184 (5): 2620–2626.
The CCL3/Macrophage Inflammatory Protein-1α–Binding Protein Evasin-1 Protects from Graft-versus-Host Disease but Does Not Modify Graft-versus-Leukemia in Mice
Marina G. M. Castor; Bárbara Rezende; Carolina B. Resende; Ana L. Alessandri; Caio T. Fagundes; Lirlândia P. Sousa; Rosa M. E. Arantes; Danielle G. Souza; Tarcília A. Silva; Amanda E. I. Proudfoot; Mauro M. Teixeira; Vanessa Pinho
J Immunol (2010) 184 (5): 2646–2654.
Transcriptional Regulation of the Endogenous Danger Signal Tenascin-C: A Novel Autocrine Loop in Inflammation
J Immunol (2010) 184 (5): 2655–2662.
A Physiological Function of Inflammation-Associated SerpinB2 Is Regulation of Adaptive Immunity
Wayne A. Schroder; Thuy T. T. Le; Lee Major; Shayna Street; Joy Gardner; Eleanore Lambley; Kate Markey; Kelli P. MacDonald; Richard J. Fish; Ranjeny Thomas; Andreas Suhrbier
J Immunol (2010) 184 (5): 2663–2670.
Monocyte Chemoattractant Protein-1 Contributes to Gut Homeostasis and Intestinal Inflammation by Composition of IL-10–Producing Regulatory Macrophage Subset
Yasuhiro Takada; Tadakazu Hisamatsu; Nobuhiko Kamada; Mina T. Kitazume; Haruki Honda; Yosuke Oshima; Riko Saito; Tetsuro Takayama; Taku Kobayashi; Hiroshi Chinen; Yohei Mikami; Takanori Kanai; Susumu Okamoto; Toshifumi Hibi
J Immunol (2010) 184 (5): 2671–2676.
Kinetics of Chemokine–Glycosaminoglycan Interactions Control Neutrophil Migration into the Airspaces of the Lungs
Yoshi Tanino; Deirdre R. Coombe; Sean E. Gill; Warren C. Kett; Osamu Kajikawa; Amanda E. I. Proudfoot; Timothy N. C. Wells; William C. Parks; Thomas N. Wight; Thomas R. Martin; Charles W. Frevert
J Immunol (2010) 184 (5): 2677–2685.
Complement Component C3 Binds to Activated Normal Platelets without Preceding Proteolytic Activation and Promotes Binding to Complement Receptor 1
J Immunol (2010) 184 (5): 2686–2692.
Intrahepatic IL-10 Maintains NKG2A+Ly49− Liver NK Cells in a Functionally Hyporesponsive State
J Immunol (2010) 184 (5): 2693–2701.
CLINICAL IMMUNOLOGY
TLR Activation Pathways in HIV-1–Exposed Seronegative Individuals
Mara Biasin; Luca Piacentini; Sergio Lo Caputo; Valentina Naddeo; Piera Pierotti; Manuela Borelli; Daria Trabattoni; Francesco Mazzotta; Gene M. Shearer; Mario Clerici
J Immunol (2010) 184 (5): 2710–2717.
Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue
Aleksander M. Grabiec; Sarah Krausz; Wilco de Jager; Tomasz Burakowski; Dion Groot; Marjolein E. Sanders; Berent J. Prakken; Wlodzimierz Maslinski; Eric Eldering; Paul P. Tak; Kris A. Reedquist
J Immunol (2010) 184 (5): 2718–2728.
Sustained Exogenous Expression of Therapeutic Levels of IFN-γ Ameliorates Atopic Dermatitis in NC/Nga Mice via Th1 Polarization
Kayoko Hattori; Makiya Nishikawa; Kanitta Watcharanurak; Akihiko Ikoma; Kenji Kabashima; Hiroyasu Toyota; Yuki Takahashi; Rei Takahashi; Yoshihiko Watanabe; Yoshinobu Takakura
J Immunol (2010) 184 (5): 2729–2735.
CORRECTIONS
Cutting Edge: Sympathetic nervous system increases proinflammatory cytokines and exacerbates influenza A virus pathogenesis
J Immunol (2010) 184 (5): 2736.
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Cover Image
Cover Image
On the cover: Human colonic biopsy stained for single IgGIL-1–related receptor (Sigirr) and the tight junction protein claudin-3. Sigirr (red) immunoreactivity and claudin-3 (green) immunoreactivity localize to intestinal epithelial cells on the crypt surface. Note that nuclei are stained with DAPI (blue). Khan, M., T. S. Steiner, H. P. Sham, K. S. Bergstrom, J. T. Huang, K. Assi, B. Salh, I. T. Tai, X. Li, and B. A. Vallance. 2010. The single IgG IL-1–related receptor controls TLR responses in differentiated human intestinal epithelial cells. J. Immunol. 184: 2305–2313.
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