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Volume 184, Issue 6
15 March 2010
Issue Cover
ISSN 0022-1767
EISSN 1550-6606

IN THIS ISSUE

In This Issue
J Immunol (2010) 184 (6): 2741–2742.
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BRIEF REVIEWS

T Cell Ig and Mucin Domain Proteins and Immunity
Lawrence P. Kane
J Immunol (2010) 184 (6): 2743–2749.
View articletitled, T Cell Ig and Mucin Domain Proteins and Immunity
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CUTTING EDGE

Cutting Edge: Polyinosinic:Polycytidylic Acid Boosts the Generation of Memory CD8 T Cells through Melanoma Differentiation-Associated Protein 5 Expressed in Stromal Cells
Yaming Wang; Marina Cella; Susan Gilfillan; Marco Colonna
J Immunol (2010) 184 (6): 2751–2755.
View articletitled, Cutting Edge: Polyinosinic:Polycytidylic Acid Boosts the Generation of Memory CD8 T Cells through Melanoma Differentiation-Associated Protein 5 Expressed in Stromal Cells
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Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate
Hanne Schoenen; Barbara Bodendorfer; Kelly Hitchens; Silvia Manzanero; Kerstin Werninghaus; Falk Nimmerjahn; Else Marie Agger; Steffen Stenger; Peter Andersen; Jürgen Ruland; Gordon D. Brown; Christine Wells; Roland Lang
J Immunol (2010) 184 (6): 2756–2760.
View articletitled, Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate
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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

The Association of MHC Class I Proteins with the 2B4 Receptor Inhibits Self-Killing of Human NK Cells
Gili Betser-Cohen; Saar Mizrahi; Moran Elboim; Osnat Alsheich-Bartok; Ofer Mandelboim
J Immunol (2010) 184 (6): 2761–2768.
View articletitled, The Association of MHC Class I Proteins with the 2B4 Receptor Inhibits Self-Killing of Human NK Cells
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In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis
Martin Guimond; Aharon G. Freud; Hsiaoyin C. Mao; Jianhua Yu; Bradley W. Blaser; Jeffrey W. Leong; Jeffrey B. Vandeusen; Adrienne Dorrance; Jianying Zhang; Crystal L. Mackall; Michael A. Caligiuri
J Immunol (2010) 184 (6): 2769–2775.
View articletitled, In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis
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ADP-Ribosylation Controls the Outcome of Tolerance or Enhanced Priming Following Mucosal Immunization
Annemarie Hasselberg; Lena Ekman; Linda Fahlén Yrlid; Karin Schön; Nils Y. Lycke
J Immunol (2010) 184 (6): 2776–2784.
View articletitled, ADP-Ribosylation Controls the Outcome of Tolerance or Enhanced Priming Following Mucosal Immunization
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Requirement for Runx Proteins in IgA Class Switching Acting Downstream of TGF-β1 and Retinoic Acid Signaling
Kakeru Watanabe; Manabu Sugai; Yukiko Nambu; Motomi Osato; Tatsunari Hayashi; Miho Kawaguchi; Toshihisa Komori; Yoshiaki Ito; Akira Shimizu
J Immunol (2010) 184 (6): 2785–2792.
View articletitled, Requirement for Runx Proteins in IgA Class Switching Acting Downstream of TGF-β1 and Retinoic Acid Signaling
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c-Myb Promotes the Survival of CD4+CD8+ Double-Positive Thymocytes through Upregulation of Bcl-xL
Joan Yuan; Rowena B. Crittenden; Timothy P. Bender
J Immunol (2010) 184 (6): 2793–2804.
View articletitled, c-Myb Promotes the Survival of CD4<sup>+</sup>CD8<sup>+</sup> Double-Positive Thymocytes through Upregulation of Bcl-xL
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SHIP Is Required for Dendritic Cell Maturation
Frann Antignano; Mariko Ibaraki; Connie Kim; Jens Ruschmann; Angela Zhang; Cheryl D. Helgason; Gerald Krystal
J Immunol (2010) 184 (6): 2805–2813.
View articletitled, SHIP Is Required for Dendritic Cell Maturation
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Neisseria gonorrhoeae Enhances HIV-1 Infection of Primary Resting CD4+ T Cells through TLR2 Activation
Jian Ding; Aprille Rapista; Natalia Teleshova; Goar Mosoyan; Gary A. Jarvis; Mary E. Klotman; Theresa L. Chang
J Immunol (2010) 184 (6): 2814–2824.
View articletitled, <em>Neisseria gonorrhoeae</em> Enhances HIV-1 Infection of Primary Resting CD4<sup>+</sup> T Cells through TLR2 Activation
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CD8 T Cell Cross-Reactivity Networks Mediate Heterologous Immunity in Human EBV and Murine Vaccinia Virus Infections
Markus Cornberg; Shalyn C. Clute; Levi B. Watkin; Frances M. Saccoccio; Sung-Kwon Kim; Yuri N. Naumov; Michael A. Brehm; Nuray Aslan; Raymond M. Welsh; Liisa K. Selin
J Immunol (2010) 184 (6): 2825–2838.
View articletitled, CD8 T Cell Cross-Reactivity Networks Mediate Heterologous Immunity in Human EBV and Murine Vaccinia Virus Infections
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Contribution of Myelin Autoantigen Citrullination to T Cell Autoaggression in the Central Nervous System
Antonio Carrillo-Vico; Melanie D. Leech; Stephen M. Anderton
J Immunol (2010) 184 (6): 2839–2846.
View articletitled, Contribution of Myelin Autoantigen Citrullination to T Cell Autoaggression in the Central Nervous System
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Adenosine Deaminase Modulation of Telomerase Activity and Replicative Senescence in Human CD8 T Lymphocytes
Stanley T. Parish; Sarah Kim; Rekha K. Sekhon; Jennifer E. Wu; Yukako Kawakatsu; Rita B. Effros
J Immunol (2010) 184 (6): 2847–2854.
View articletitled, Adenosine Deaminase Modulation of Telomerase Activity and Replicative Senescence in Human CD8 T Lymphocytes
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IFN-γ Receptor Signaling Regulates Memory CD8+ T Cell Differentiation
Özen Sercan; Diana Stoycheva; Günter J. Hämmerling; Bernd Arnold; Thomas Schüler
J Immunol (2010) 184 (6): 2855–2862.
View articletitled, IFN-γ Receptor Signaling Regulates Memory CD8<sup>+</sup> T Cell Differentiation
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Reactive Oxygen Species Level Defines Two Functionally Distinctive Stages of Inflammatory Dendritic Cell Development from Mouse Bone Marrow
Kuo-Ching Sheng; Geoffrey A. Pietersz; Choon Kit Tang; Paul A. Ramsland; Vasso Apostolopoulos
J Immunol (2010) 184 (6): 2863–2872.
View articletitled, Reactive Oxygen Species Level Defines Two Functionally Distinctive Stages of Inflammatory Dendritic Cell Development from Mouse Bone Marrow
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Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node
Jennifer J. Linderman; Thomas Riggs; Manjusha Pande; Mark Miller; Simeone Marino; Denise E. Kirschner
J Immunol (2010) 184 (6): 2873–2885.
View articletitled, Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node
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Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver
Ye H. Oo; Chris J. Weston; Patricia F. Lalor; Stuart M. Curbishley; David R. Withers; Gary M. Reynolds; Shishir Shetty; Jehan Harki; Jean C. Shaw; Bertus Eksteen; Stefan G. Hubscher; Lucy S. K. Walker; David H. Adams
J Immunol (2010) 184 (6): 2886–2898.
View articletitled, Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver
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Dendritic Cells Derived from Hemozoin-Loaded Monocytes Display a Partial Maturation Phenotype that Promotes HIV-1 Trans-Infection of CD4+ T Cells and Virus Replication
Juliette Diou; Mélanie R. Tardif; Corinne Barat; Michel J. Tremblay
J Immunol (2010) 184 (6): 2899–2907.
View articletitled, Dendritic Cells Derived from Hemozoin-Loaded Monocytes Display a Partial Maturation Phenotype that Promotes HIV-1 <em>Trans</em>-Infection of CD4<sup>+</sup> T Cells and Virus Replication
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Antiviral Response Dictated by Choreographed Cascade of Transcription Factors
Elena Zaslavsky; Uri Hershberg; Jeremy Seto; Alissa M. Pham; Susanna Marquez; Jamie L. Duke; James G. Wetmur; Benjamin R. tenOever; Stuart C. Sealfon; Steven H. Kleinstein
J Immunol (2010) 184 (6): 2908–2917.
View articletitled, Antiviral Response Dictated by Choreographed Cascade of Transcription Factors
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Glutathione-Redox Balance Regulates c-rel–Driven IL-12 Production in Macrophages: Possible Implications in Antituberculosis Immunotherapy
Kaiser Alam; Sheikh Ghousunnissa; Shiny Nair; Vijaya Lakshmi Valluri; Sangita Mukhopadhyay
J Immunol (2010) 184 (6): 2918–2929.
View articletitled, Glutathione-Redox Balance Regulates c-rel–Driven IL-12 Production in Macrophages: Possible Implications in Antituberculosis Immunotherapy
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In Vivo Imaging of an Inducible Oncogenic Tumor Antigen Visualizes Tumor Progression and Predicts CTL Tolerance
Christian Buschow; Jehad Charo; Kathleen Anders; Christoph Loddenkemper; Ana Jukica; Wisam Alsamah; Cynthia Perez; Gerald Willimsky; Thomas Blankenstein
J Immunol (2010) 184 (6): 2930–2938.
View articletitled, In Vivo Imaging of an Inducible Oncogenic Tumor Antigen Visualizes Tumor Progression and Predicts CTL Tolerance
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Ischemic Injury Enhances Dendritic Cell Immunogenicity via TLR4 and NF-κB Activation
Mollie Jurewicz; Ayumi Takakura; Andrea Augello; Said Movahedi Naini; Takaharu Ichimura; Kambiz Zandi-Nejad; Reza Abdi
J Immunol (2010) 184 (6): 2939–2948.
View articletitled, Ischemic Injury Enhances Dendritic Cell Immunogenicity via TLR4 and NF-κB Activation
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Modulation of T Lymphocyte Function by the Pregnane X Receptor
Sandrine Dubrac; Andreas Elentner; Susanne Ebner; Jutta Horejs-Hoeck; Matthias Schmuth
J Immunol (2010) 184 (6): 2949–2957.
View articletitled, Modulation of T Lymphocyte Function by the Pregnane X Receptor
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Diversity of the CD8+ T Cell Repertoire Elicited against an Immunodominant Epitope Does Not Depend on the Context of Infection
Brian D. Rudd; Vanessa Venturi; Megan J. Smithey; Sing Sing Way; Miles P. Davenport; Janko Nikolich-Žugich
J Immunol (2010) 184 (6): 2958–2965.
View articletitled, Diversity of the CD8<sup>+</sup> T Cell Repertoire Elicited against an Immunodominant Epitope Does Not Depend on the Context of Infection
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Differential Recruitment of Activating and Inhibitory FcγRII during Phagocytosis
Sujata Syam; Patricia Mero; Theodore Pham; Courtney A. McIntosh; Pierre Bruhns; James W. Booth
J Immunol (2010) 184 (6): 2966–2973.
View articletitled, Differential Recruitment of Activating and Inhibitory FcγRII during Phagocytosis
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Dibutyl Phthalate-Induced Thymic Stromal Lymphopoietin Is Required for Th2 Contact Hypersensitivity Responses
Ryan P. Larson; Simone C. Zimmerli; Michael R. Comeau; Andrea Itano; Miyuki Omori; Masanori Iseki; Conrad Hauser; Steven F. Ziegler
J Immunol (2010) 184 (6): 2974–2984.
View articletitled, Dibutyl Phthalate-Induced Thymic Stromal Lymphopoietin Is Required for Th2 Contact Hypersensitivity Responses
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Post-Endoplasmic Reticulum Rescue of Unstable MHC Class I Requires Proprotein Convertase PC7
Ralf M. Leonhardt; Dorothee Fiegl; Elke Rufer; Axel Karger; Barbara Bettin; Michael R. Knittler
J Immunol (2010) 184 (6): 2985–2998.
View articletitled, Post-Endoplasmic Reticulum Rescue of Unstable MHC Class I Requires Proprotein Convertase PC7
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Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+ Regulatory T Cells in Human Thymus
Shino Hanabuchi; Tomoki Ito; Woon-Ryon Park; Norihiko Watanabe; Joanne L. Shaw; Eulogia Roman; Kazuhiko Arima; Yui-Hsi Wang; Kui Shin Voo; Wei Cao; Yong-Jun Liu
J Immunol (2010) 184 (6): 2999–3007.
View articletitled, Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3<sup>+</sup> Regulatory T Cells in Human Thymus
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Transfusion of Nonobese Diabetic Mice with Allogeneic Newborn Blood Ameliorates Autoimmune Diabetes and Modifies the Expression of Selected Immune Response Genes
Sundararajan Jayaraman; Tejas Patel; Vasu Patel; Shahnaz Ajani; Rebecca Garza; Arathi Jayaraman; Sung Kwon; Rajvir Singh; Damiano Rondelli; Bellur S. Prabhakar; Mark Holterman
J Immunol (2010) 184 (6): 3008–3015.
View articletitled, Transfusion of Nonobese Diabetic Mice with Allogeneic Newborn Blood Ameliorates Autoimmune Diabetes and Modifies the Expression of Selected Immune Response Genes
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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Splicing of Distant Peptide Fragments Occurs in the Proteasome by Transpeptidation and Produces the Spliced Antigenic Peptide Derived from Fibroblast Growth Factor-5
Alexandre Dalet; Nathalie Vigneron; Vincent Stroobant; Ken-ichi Hanada; Benoît J. Van den Eynde
J Immunol (2010) 184 (6): 3016–3024.
View articletitled, Splicing of Distant Peptide Fragments Occurs in the Proteasome by Transpeptidation and Produces the Spliced Antigenic Peptide Derived from Fibroblast Growth Factor-5
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MyD88 Adaptor-Like D96N Is a Naturally Occurring Loss-of-Function Variant of TIRAP
Julie George; Andriy V. Kubarenko; Anna Rautanen; Tara C. Mills; Elif Colak; Tore Kempf; Adrian V. S. Hill; Alexandra Nieters; Alexander N. R. Weber
J Immunol (2010) 184 (6): 3025–3032.
View articletitled, MyD88 Adaptor-Like D96N Is a Naturally Occurring Loss-of-Function Variant of <em>TIRAP</em>
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Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells
Nicolas Blanchard; Takayuki Kanaseki; Hernando Escobar; Frédéric Delebecque; Niranjana A. Nagarajan; Eduardo Reyes-Vargas; David K. Crockett; David H. Raulet; Julio C. Delgado; Nilabh Shastri
J Immunol (2010) 184 (6): 3033–3042.
View articletitled, Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells
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The Human IL-3/Granulocyte-Macrophage Colony-Stimulating Factor Locus Is Epigenetically Silent in Immature Thymocytes and Is Progressively Activated during T Cell Development
Fabio Mirabella; Euan W. Baxter; Marjorie Boissinot; Sally R. James; Peter N. Cockerill
J Immunol (2010) 184 (6): 3043–3054.
View articletitled, The Human IL-3/Granulocyte-Macrophage Colony-Stimulating Factor Locus Is Epigenetically Silent in Immature Thymocytes and Is Progressively Activated during T Cell Development
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IMMUNOGENETICS

The Major Locus for Mouse Adenovirus Susceptibility Maps to Genes of the Hematopoietic Cell Surface-Expressed LY6 Family
Katherine R. Spindler; Amanda R. Welton; Efrem S. Lim; Suman Duvvuru; Irene W. Althaus; Jennifer E. Imperiale; Adam I. Daoud; Elissa J. Chesler
J Immunol (2010) 184 (6): 3055–3062.
View articletitled, The Major Locus for Mouse Adenovirus Susceptibility Maps to Genes of the Hematopoietic Cell Surface-Expressed LY6 Family
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HOST DEFENSE

Public TCR Use by Herpes Simplex Virus-2–Specific Human CD8 CTLs
Lichun Dong; Penny Li; Tjitske Oenema; Christopher L. McClurkan; David M. Koelle
J Immunol (2010) 184 (6): 3063–3071.
View articletitled, Public TCR Use by Herpes Simplex Virus-2–Specific Human CD8 CTLs
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Essential Role of Mitochondrial Antiviral Signaling, IFN Regulatory Factor (IRF)3, and IRF7 in Chlamydophila pneumoniae-Mediated IFN-β Response and Control of Bacterial Replication in Human Endothelial Cells
Claudia Buß; Bastian Opitz; Andreas C. Hocke; Juliane Lippmann; Vincent van Laak; Stefan Hippenstiel; Matthias Krüll; Norbert Suttorp; Julia Eitel
J Immunol (2010) 184 (6): 3072–3078.
View articletitled, Essential Role of Mitochondrial Antiviral Signaling, IFN Regulatory Factor (IRF)3, and IRF7 in <em>Chlamydophila pneumoniae</em>-Mediated IFN-β Response and Control of Bacterial Replication in Human Endothelial Cells
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Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis
W. Joost Wiersinga; Liesbeth M. Kager; Joppe W. R. Hovius; Gerritje J. W. van der Windt; Alex F. de Vos; Joost C. M. Meijers; Joris J. Roelofs; Arjen Dondorp; Marcel Levi; Nicholas P. Day; Sharon J. Peacock; Tom van der Poll
J Immunol (2010) 184 (6): 3079–3086.
View articletitled, Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis
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CC Chemokine Ligand 3 Overcomes the Bacteriocidal and Phagocytic Defect of Macrophages and Hastens Recovery from Experimental Otitis Media in TNF−/− Mice
Anke Leichtle; Michelle Hernandez; Joerg Ebmeyer; Kenshi Yamasaki; Yuping Lai; Katherine Radek; Yun-Hoon Choung; Sara Euteneuer; Kwang Pak; Richard Gallo; Stephen I. Wasserman; Allen F. Ryan
J Immunol (2010) 184 (6): 3087–3097.
View articletitled, CC Chemokine Ligand 3 Overcomes the Bacteriocidal and Phagocytic Defect of Macrophages and Hastens Recovery from Experimental Otitis Media in TNF<sup>−/−</sup> Mice
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The p110δ Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti-Leishmania Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets
Dong Liu; Jude E. Uzonna
J Immunol (2010) 184 (6): 3098–3105.
View articletitled, The p110δ Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti-<em>Leishmania</em> Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets
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Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells
Srinivas Nagaraj; Adam G. Schrum; Hyun-Il Cho; Esteban Celis; Dmitry I. Gabrilovich
J Immunol (2010) 184 (6): 3106–3116.
View articletitled, Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells
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Nitric Oxide Is Involved in Mycobacterium bovis Bacillus Calmette-Guérin–Activated Jagged1 and Notch1 Signaling
Nisha Kapoor; Yeddula Narayana; Shripad A. Patil; Kithiganahalli N. Balaji
J Immunol (2010) 184 (6): 3117–3126.
View articletitled, Nitric Oxide Is Involved in <em>Mycobacterium bovis</em> Bacillus Calmette-Guérin–Activated Jagged1 and Notch1 Signaling
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Diet-Induced Obesity Impairs the T Cell Memory Response to Influenza Virus Infection
Erik A. Karlsson; Patricia A. Sheridan; Melinda A. Beck
J Immunol (2010) 184 (6): 3127–3133.
View articletitled, Diet-Induced Obesity Impairs the T Cell Memory Response to Influenza Virus Infection
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Dendritic Cell Inhibition Is Connected to Exhaustion of CD8+ T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection
Ian Gaël Rodrigue-Gervais; Hawley Rigsby; Loubna Jouan; Dominike Sauvé; Rafick-Pierre Sékaly; Bernard Willems; Daniel Lamarre
J Immunol (2010) 184 (6): 3134–3144.
View articletitled, Dendritic Cell Inhibition Is Connected to Exhaustion of CD8<sup>+</sup> T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection
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INFLAMMATION

Protein Kinase D1 Is Essential for the Proinflammatory Response Induced by Hypersensitivity Pneumonitis-Causing Thermophilic Actinomycetes Saccharopolyspora rectivirgula
Young-In Kim; Jeoung-Eun Park; David D. Brand; Elizabeth A. Fitzpatrick; Ae-Kyung Yi
J Immunol (2010) 184 (6): 3145–3156.
View articletitled, Protein Kinase D1 Is Essential for the Proinflammatory Response Induced by Hypersensitivity Pneumonitis-Causing Thermophilic Actinomycetes <em>Saccharopolyspora rectivirgula</em>
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The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-κB
Jamie R. Privratsky; Benjamin E. Tourdot; Debra K. Newman; Peter J. Newman
J Immunol (2010) 184 (6): 3157–3163.
View articletitled, The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-κB
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Small-Molecule Inhibitors of Vascular Adhesion Protein-1 Reduce the Accumulation of Myeloid Cells into Tumors and Attenuate Tumor Growth in Mice
Fumiko Marttila-Ichihara; Karolien Castermans; Kaisa Auvinen; Mirjam G. A. oude Egbrink; Sirpa Jalkanen; Arjan W. Griffioen; Marko Salmi
J Immunol (2010) 184 (6): 3164–3173.
View articletitled, Small-Molecule Inhibitors of Vascular Adhesion Protein-1 Reduce the Accumulation of Myeloid Cells into Tumors and Attenuate Tumor Growth in Mice
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Substrain Differences Reveal Novel Disease-Modifying Gene Candidates That Alter the Clinical Course of a Rodent Model of Multiple Sclerosis
Leslie E. Summers deLuca; Natalia B. Pikor; Jennifer O’Leary; Georgina Galicia-Rosas; Lesley A. Ward; Dustin Defreitas; Trisha M. Finlay; Shalina S. Ousman; Lucy R. Osborne; Jennifer L. Gommerman
J Immunol (2010) 184 (6): 3174–3185.
View articletitled, Substrain Differences Reveal Novel Disease-Modifying Gene Candidates That Alter the Clinical Course of a Rodent Model of Multiple Sclerosis
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IL-4 Regulates Skin Homeostasis and the Predisposition toward Allergic Skin Inflammation
Sarita Sehra; Yongxue Yao; Michael D. Howell; Evelyn T. Nguyen; Geoffrey S. Kansas; Donald Y. M. Leung; Jeffrey B. Travers; Mark H. Kaplan
J Immunol (2010) 184 (6): 3186–3190.
View articletitled, IL-4 Regulates Skin Homeostasis and the Predisposition toward Allergic Skin Inflammation
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Phosphatidylserine-Containing Liposomes Inhibit the Differentiation of Osteoclasts and Trabecular Bone Loss
Zhou Wu; Hong Mei Ma; Toshio Kukita; Yoshinobu Nakanishi; Hiroshi Nakanishi
J Immunol (2010) 184 (6): 3191–3201.
View articletitled, Phosphatidylserine-Containing Liposomes Inhibit the Differentiation of Osteoclasts and Trabecular Bone Loss
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Chemokine Scavenger D6 Is Expressed by Trophoblasts and Aids the Survival of Mouse Embryos Transferred into Allogeneic Recipients
Judith Madigan; Dilys J. Freeman; Fiona Menzies; Steve Forrow; Scott M. Nelson; Anne Young; Andrew Sharkey; Ashley Moffett; Gerard J. Graham; Ian A. Greer; Antal Rot; Robert J. B. Nibbs
J Immunol (2010) 184 (6): 3202–3212.
View articletitled, Chemokine Scavenger D6 Is Expressed by Trophoblasts and Aids the Survival of Mouse Embryos Transferred into Allogeneic Recipients
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PI3K-Dependent Upregulation of Mcl-1 by Human Cytomegalovirus Is Mediated by Epidermal Growth Factor Receptor and Inhibits Apoptosis in Short-Lived Monocytes
Gary Chan; Maciej T. Nogalski; Gretchen L. Bentz; M. Shane Smith; Alexander Parmater; Andrew D. Yurochko
J Immunol (2010) 184 (6): 3213–3222.
View articletitled, PI3K-Dependent Upregulation of Mcl-1 by Human Cytomegalovirus Is Mediated by Epidermal Growth Factor Receptor and Inhibits Apoptosis in Short-Lived Monocytes
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Matricellular Protein CCN1 Activates a Proinflammatory Genetic Program in Murine Macrophages
Tao Bai; Chih-Chiun Chen; Lester F. Lau
J Immunol (2010) 184 (6): 3223–3232.
View articletitled, Matricellular Protein CCN1 Activates a Proinflammatory Genetic Program in Murine Macrophages
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IL-17 Contributes to Angiogenesis in Rheumatoid Arthritis
Sarah R. Pickens; Michael V. Volin; Arthur M. Mandelin, II; Jay K. Kolls; Richard M. Pope; Shiva Shahrara
J Immunol (2010) 184 (6): 3233–3241.
View articletitled, IL-17 Contributes to Angiogenesis in Rheumatoid Arthritis
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CLINICAL IMMUNOLOGY

Intense Antiextracellular Adaptive Immune Response to Human Cytomegalovirus in Very Old Subjects with Impaired Health and Cognitive and Functional Status
Rosanna Vescovini; Claudia Biasini; Anna Rita Telera; Manuela Basaglia; Adriano Stella; Francesca Magalini; Laura Bucci; Daniela Monti; Tiziana Lazzarotto; Paola Dal Monte; Mario Pedrazzoni; Maria Cristina Medici; Carlo Chezzi; Claudio Franceschi; Francesco F. Fagnoni; Paolo Sansoni
J Immunol (2010) 184 (6): 3242–3249.
View articletitled, Intense Antiextracellular Adaptive Immune Response to Human Cytomegalovirus in Very Old Subjects with Impaired Health and Cognitive and Functional Status
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Detailed Characterization of T Cell Responses to Herpes Simplex Virus-2 in Immune Seronegative Persons
Christine M. Posavad; Michael Remington; Dawn E. Mueller; Lin Zhao; Amalia S. Magaret; Anna Wald; Lawrence Corey
J Immunol (2010) 184 (6): 3250–3259.
View articletitled, Detailed Characterization of T Cell Responses to Herpes Simplex Virus-2 in Immune Seronegative Persons
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Vγ9Vδ2 T Lymphocytes Efficiently Recognize and Kill Zoledronate-Sensitized, Imatinib-Sensitive, and Imatinib-Resistant Chronic Myelogenous Leukemia Cells
Matilde D’Asaro; Carmela La Mendola; Diana Di Liberto; Valentina Orlando; Matilde Todaro; Marisa Spina; Giuliana Guggino; Serena Meraviglia; Nadia Caccamo; Angelo Messina; Alfredo Salerno; Francesco Di Raimondo; Paolo Vigneri; Giorgio Stassi; Jean Jacques Fourniè; Francesco Dieli
J Immunol (2010) 184 (6): 3260–3268.
View articletitled, Vγ9Vδ2 T Lymphocytes Efficiently Recognize and Kill Zoledronate-Sensitized, Imatinib-Sensitive, and Imatinib-Resistant Chronic Myelogenous Leukemia Cells
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Immunological Property of Antibodies against N-Glycolylneuraminic Acid Epitopes in Cytidine Monophospho–N-Acetylneuraminic Acid Hydroxylase-Deficient Mice
Hiroyuki Tahara; Kentaro Ide; Nabin Bahadur Basnet; Yuka Tanaka; Haruo Matsuda; Hiromu Takematsu; Yasunori Kozutsumi; Hideki Ohdan
J Immunol (2010) 184 (6): 3269–3275.
View articletitled, Immunological Property of Antibodies against <em>N</em>-Glycolylneuraminic Acid Epitopes in Cytidine Monophospho–<em>N</em>-Acetylneuraminic Acid Hydroxylase-Deficient Mice
Supplementary data
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The Endoplasmic Reticulum Stress-Inducible Protein, Herp, Is a Potential Triggering Antigen for Anti-DNA Response
Yasuhiko Hirabayashi; Yumiko Oka; Tomoko Ikeda; Hiroshi Fujii; Tomonori Ishii; Takeshi Sasaki; Hideo Harigae
J Immunol (2010) 184 (6): 3276–3283.
View articletitled, The Endoplasmic Reticulum Stress-Inducible Protein, Herp, Is a Potential Triggering Antigen for Anti-DNA Response
Supplementary data
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A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs
Michael F. Denny; Srilakshmi Yalavarthi; Wenpu Zhao; Seth G. Thacker; Marc Anderson; Ashley R. Sandy; W. Joseph McCune; Mariana J. Kaplan
J Immunol (2010) 184 (6): 3284–3297.
View articletitled, A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs
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CORRECTIONS

IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
Tomohiro Yoshimoto; Takayuki Yoshimoto; Koubun Yasuda; Junichiro Mizuguchi; Kenji Nakanishi
J Immunol (2010) 184 (6): 3298.
View articletitled, IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
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  • Cover Image

    Cover Image

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    On the cover: Our virtual model represents events occurring in the T zone of a lymph node, represented by a grid (only a portion is shown). Cells move onto, off of, and around the grid. T cells and dendritic cells enter the lymph node and can move to any adjacent square; T cells can divide, and cells in adjacent squares can interact. Linderman, J. J., T. Riggs, M. Pande, M. Miller, S. Marino, and D. E. Kirschner. 2010. Characterizing the dynamics of CD4+ T cell priming within a lymph node. J. Immunol. 184: 2873–2885.

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