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Issues
15 April 2010
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: IFN-γ Is a Negative Regulator of IL-23 in Murine Macrophages and Experimental Colitis
J Immunol (2010) 184 (8): 4069–4073.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke
Bing Zhang; Sandhya Subramanian; Suzan Dziennis; Jia Jia; Masayoshi Uchida; Kozaburo Akiyoshi; Elton Migliati; Anne D. Lewis; Arthur A. Vandenbark; Halina Offner; Patricia D. Hurn
J Immunol (2010) 184 (8): 4087–4094.
Dynamic Regulation of CD8 T Cell Tolerance Induction by Liver Sinusoidal Endothelial Cells
Anna Schurich; Martina Berg; Dirk Stabenow; Jan Böttcher; Michaela Kern; Hans-Jörg Schild; Christian Kurts; Verena Schuette; Sven Burgdorf; Linda Diehl; Andreas Limmer; Percy A. Knolle
J Immunol (2010) 184 (8): 4107–4114.
Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses
Scott E. Hensley; Damien Zanker; Brian P. Dolan; Alexandre David; Heather D. Hickman; Alan C. Embry; Cara N. Skon; Kristie M. Grebe; Thomas A. Griffin; Weisan Chen; Jack R. Bennink; Jonathan W. Yewdell
J Immunol (2010) 184 (8): 4115–4122.
Peripheral B Cell Tolerance and Function in Transgenic Mice Expressing an IgD Superantigen
Bao Hoa Duong; Takayuki Ota; Djemel Aït-Azzouzene; Miyo Aoki-Ota; José Luis Vela; Christoph Huber; Kevin Walsh; Amanda L. Gavin; David Nemazee
J Immunol (2010) 184 (8): 4143–4158.
Lck Mediates Th2 Differentiation through Effects on T-bet and GATA-3
J Immunol (2010) 184 (8): 4178–4184.
Relative Over-Reactivity of Human versus Chimpanzee Lymphocytes: Implications for the Human Diseases Associated with Immune Activation
J Immunol (2010) 184 (8): 4185–4195.
Toxin-Coupled MHC Class I Tetramers Can Specifically Ablate Autoreactive CD8+ T Cells and Delay Diabetes in Nonobese Diabetic Mice
Benjamin G. Vincent; Ellen F. Young; Adam S. Buntzman; Rosemary Stevens; Thomas B. Kepler; Roland M. Tisch; Jeffrey A. Frelinger; Paul R. Hess
J Immunol (2010) 184 (8): 4196–4204.
An Autoimmune Response to Odorant Binding Protein 1a Is Associated with Dry Eye in the Aire-Deficient Mouse
Jason J. DeVoss; Norbert P. LeClair; Yafei Hou; Navdeep K. Grewal; Kellsey P. Johannes; Wen Lu; Ting Yang; Craig Meagher; Lawrence Fong; Erich C. Strauss; Mark S. Anderson
J Immunol (2010) 184 (8): 4236–4246.
Differential IL-17 Production and Mannan Recognition Contribute to Fungal Pathogenicity and Commensalism
Lisa Rizzetto; Mirela Kuka; Carlotta De Filippo; Alessandra Cambi; Mihai G. Netea; Luca Beltrame; Giorgio Napolitani; Maria Gabriella Torcia; Ugo D’Oro; Duccio Cavalieri
J Immunol (2010) 184 (8): 4258–4268.
Mathematical Modeling of Chimeric TCR Triggering Predicts the Magnitude of Target Lysis and Its Impairment by TCR Downmodulation
Scott E. James; Philip D. Greenberg; Michael C. Jensen; Yukang Lin; Jinjuan Wang; Lihua E. Budde; Brian G. Till; Andrew A. Raubitschek; Stephen J. Forman; Oliver W. Press
J Immunol (2010) 184 (8): 4284–4294.
Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells
Ling Lu; Julie Wang; Feng Zhang; Yang Chai; David Brand; Xuehao Wang; David A. Horwitz; Wei Shi; Song Guo Zheng
J Immunol (2010) 184 (8): 4295–4306.
Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO
Nicola J. Booth; Arthur J. McQuaid; Toni Sobande; Steve Kissane; Elaine Agius; Sarah E. Jackson; Mike Salmon; Francesco Falciani; Kwee Yong; Malcolm H. Rustin; Arne N. Akbar; Milica Vukmanovic-Stejic
J Immunol (2010) 184 (8): 4317–4326.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
IMMUNOGENETICS
Adaptive Interactions between HLA and HIV-1: Highly Divergent Selection Imposed by HLA Class I Molecules with Common Supertype Motifs
Mina John; David Heckerman; Ian James; Lawrence P. Park; Jonathan M. Carlson; Abha Chopra; Silvana Gaudieri; David Nolan; David W. Haas; Sharon A. Riddler; Richard Haubrich; Simon Mallal
J Immunol (2010) 184 (8): 4368–4377.
HOST DEFENSE
Lysophosphatidylcholine Increases Neutrophil Bactericidal Activity by Enhancement of Azurophil Granule-Phagosome Fusion via Glycine·GlyRα2/TRPM2/p38 MAPK Signaling
Chang-Won Hong; Taek-Keun Kim; Hwa-Yong Ham; Ju-Suk Nam; Yong Ho Kim; Haifeng Zheng; Bo Pang; Tae-Kwon Min; Jun-Sub Jung; Si-Nae Lee; Hyun-Jeong Cho; Ee-Jin Kim; In-Hwan Hong; Tae-Cheon Kang; Jongho Lee; Seog Bae Oh; Sung Jun Jung; Sung Joon Kim; Dong-Keun Song
J Immunol (2010) 184 (8): 4401–4413.
Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung
Yuko Okamoto Yoshida; Masayuki Umemura; Ayano Yahagi; Rebecca L. O’Brien; Koichi Ikuta; Kenji Kishihara; Hiromitsu Hara; Susumu Nakae; Yoichiro Iwakura; Goro Matsuzaki
J Immunol (2010) 184 (8): 4414–4422.
Single-Chain HLA-A2 MHC Trimers That Incorporate an Immundominant Peptide Elicit Protective T Cell Immunity against Lethal West Nile Virus Infection
Sojung Kim; Lijin Li; Curtis P. McMurtrey; William H. Hildebrand; Jon A. Weidanz; William E. Gillanders; Michael S. Diamond; Ted H. Hansen
J Immunol (2010) 184 (8): 4423–4430.
INFLAMMATION
Overexpression of CXC Chemokine Ligand 14 Exacerbates Collagen-Induced Arthritis
Limo Chen; Linjie Guo; Jun Tian; Hongxia He; Ekaterina Marinova; Pumin Zhang; Biao Zheng; Shuhua Han
J Immunol (2010) 184 (8): 4455–4459.
Inhibitor of NF-κB Kinases α and β Are Both Essential for High Mobility Group Box 1-Mediated Chemotaxis
Marianna Penzo; Raffaella Molteni; Tomomi Suda; Sylvia Samaniego; Angela Raucci; David M. Habiel; Frederick Miller; Hui-ping Jiang; Jun Li; Ruggero Pardi; Roberta Palumbo; Eleonora Olivotto; Richard R. Kew; Marco E. Bianchi; Kenneth B. Marcu
J Immunol (2010) 184 (8): 4497–4509.
Polycomb Group Gene Product Ring1B Regulates Th2-Driven Airway Inflammation through the Inhibition of Bim-Mediated Apoptosis of Effector Th2 Cells in the Lung
Akane Suzuki; Chiaki Iwamura; Kenta Shinoda; Damon J. Tumes; Motoko Y. Kimura; Hiroyuki Hosokawa; Yusuke Endo; Shu Horiuchi; Koji Tokoyoda; Haruhiko Koseki; Masakatsu Yamashita; Toshinori Nakayama
J Immunol (2010) 184 (8): 4510–4520.
Ontogeny of Stromal Organizer Cells during Lymph Node Development
Cécile Bénézech; Andrea White; Emma Mader; Karine Serre; Sonia Parnell; Klaus Pfeffer; Carl F. Ware; Graham Anderson; Jorge H. Caamaño
J Immunol (2010) 184 (8): 4521–4530.
IL-17 Promotes p38 MAPK-Dependent Endothelial Activation Enhancing Neutrophil Recruitment to Sites of Inflammation
Lucie Roussel; François Houle; Carlos Chan; Yu Yao; Julie Bérubé; Ron Olivenstein; James G. Martin; Jacques Huot; Qutayba Hamid; Lorenzo Ferri; Simon Rousseau
J Immunol (2010) 184 (8): 4531–4537.
Access to the Spleen Microenvironment through Lymph Shows Local Cytokine Production, Increased Cell Flux, and Altered Signaling of Immune Cells during Lipopolysaccharide-Induced Acute Inflammation
Elvira Semaeva; Olav Tenstad; Jørn Skavland; Marianne Enger; Per Ole Iversen; Bjørn Tore Gjertsen; Helge Wiig
J Immunol (2010) 184 (8): 4547–4556.
CLINICAL IMMUNOLOGY
Cell-Specific Gene Expression in Langerhans Cell Histiocytosis Lesions Reveals a Distinct Profile Compared with Epidermal Langerhans Cells
Carl E. Allen; Liunan Li; Tricia L. Peters; Hon-chiu Eastwood Leung; Alexander Yu; Tsz-Kwong Man; Sivashankarappa Gurusiddappa; Michelle T. Phillips; M. John Hicks; Amos Gaikwad; Miriam Merad; Kenneth L. McClain
J Immunol (2010) 184 (8): 4557–4567.
Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients
Pandurangan Vijayanand; Kesta Durkin; Guido Hartmann; Jaymin Morjaria; Gregory Seumois; Karl J. Staples; David Hall; Christina Bessant; Michelle Bartholomew; Peter H. Howarth; Peter S. Friedmann; Ratko Djukanović
J Immunol (2010) 184 (8): 4568–4574.
CORRECTIONS
A Th1-recognized peptide P277, when tandemly repeated, enhances a Th2 immune response toward effective vaccines against autoimmune diabetes in nonobese diabetic mice
Liang Jin; Aihua Zhu; Yu Wang; Qingmei Chen; Qiyan Xiong; Jianping Li; Yunxiao Sun; Taiming Li; Rongyue Cao; Jie Wu; Jingjing Liu
J Immunol (2010) 184 (8): 4575.
CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF−/− mice
Anke Leichtle; Michelle Hernandez; Joerg Ebmeyer; Kenshi Yamasaki; Yuping Lai; Katherine Radek; Yun-Hoon Choung; Sara Euteneuer; Kwang Pak; Richard Gallo; Stephen I. Wasserman; Allen F. Ryan
J Immunol (2010) 184 (8): 4576.
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Cover Image
Cover Image
![issue cover]()
On the cover: Odorant binding protein 1a is an important autoantigen in autoimmune dacryoadenitis. Spontaneous autoimmunity in Aire-deficient mice targets a number of different organs, including the lacrimal glands. Transfer of T lymphocytes from Aire-deficient mice stimulated with odorant binding protein 1a fusion protein results in lacrimal gland autoimmunity, as demonstrated by a massive lymphocytic infiltration into the lacrimal glands and destruction of normal tissue architecture (shown). DeVoss, J. J., N. LeClair, Y. Hou, N. Grewal, K. Johannes, W. Lu, T. Yang, C. Meagher, L. Fong, E. C. Strauss, and M. S. Anderson. 2010. An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse. J. Immunol. 184: 4236–4246.
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