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J Immunol (2010) 184 (9): 4581–4582.

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LETTERS TO THE EDITOR

Comment on “Human Pregnancy Up-regulates Tim-3 in Innate Immune Cells for Systemic Immunity”

Hai-Feng Pan; Qing-Qing Zhu; Ting-Ting Li; Dong-Qing Ye; Xiang-Pei Li

J Immunol (2010) 184 (9): 4583.

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Response to Comment on “Human Pregnancy Up-regulates Tim-3 in Innate Immune Cells for Systemic Immunity”

Jie Zhao; Bo Huang

J Immunol (2010) 184 (9): 4583–4584.

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PILLARS OF IMMUNOLOGY

The Earliest Knockouts

Michael J. Bevan

J Immunol (2010) 184 (9): 4585–4586.

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Pillars Article: β2-Microglobulin Deficient Mice Lack CD4⁻8⁺ Cytolytic T Cells. Nature. 1990. 344: 742–746

Maarten Zijlstra; Mark Bix; Neil E. Simister; Janet M. Loring; David H. Raulet; Rudolf Jaenisch

J Immunol (2010) 184 (9): 4587–4591.

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Add to Citation Manager for Pillars Article: β2-Microglobulin Deficient Mice Lack CD4<sup>−</sup>8<sup>+</sup> Cytolytic T Cells. <em>Nature</em>. 1990. 344: 742–746

Pillars Article: Normal Development of Mice Deficient in β₂M, MHC Class I Proteins, and CD8⁺ T Cells. Science. 248: 1227–1230

Beverly H. Koller; Philippa Marrack; John W. Kappler; Oliver Smithies

J Immunol (2010) 184 (9): 4592–4595.

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BRIEF REVIEWS

IgM, FcμRs, and Malarial Immune Evasion

Daniel M. Czajkowsky; Ali Salanti; Sisse B. Ditlev; Zhifeng Shao; Ashfaq Ghumra; J. Alexandra Rowe; Richard J. Pleass

J Immunol (2010) 184 (9): 4597–4603.

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CUTTING EDGE

Cutting Edge: IL-23 Receptor Deficiency Prevents the Development of Lupus Nephritis in C57BL/6–lpr/lpr Mice

Vasileios C. Kyttaris; Zheng Zhang; Vijay K. Kuchroo; Mohamed Oukka; George C. Tsokos

J Immunol (2010) 184 (9): 4605–4609.

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Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis

Patrick J. Shaw; John R. Lukens; Samir Burns; Hongbo Chi; Maureen A. McGargill; Thirumala-Devi Kanneganti

J Immunol (2010) 184 (9): 4610–4614.

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Cutting Edge: IL-21 and TLR Signaling Regulate Germinal Center Responses in a B Cell-Intrinsic Manner

Juliana Bessa; Manfred Kopf; Martin F. Bachmann

J Immunol (2010) 184 (9): 4615–4619.

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Cutting Edge: Human Latency-Associated Peptide⁺ T Cells: A Novel Regulatory T Cell Subset

Roopali Gandhi; Mauricio F. Farez; Yue Wang; Deneen Kozoriz; Francisco J. Quintana; Howard L. Weiner

J Immunol (2010) 184 (9): 4620–4624.

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Cutting Edge: Granulocyte-Macrophage Colony-Stimulating Factor Is the Major CD8⁺ T Cell-Derived Licensing Factor for Dendritic Cell Activation

Lin Min; Siti Aminah Bte Mohammad Isa; Wang Shuai; Cher Boon Piang; Fam Wee Nih; Masayo Kotaka; Christiane Ruedl

J Immunol (2010) 184 (9): 4625–4629.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Histone Acetylation at the Single-Cell Level: A Marker of Memory CD8⁺ T Cell Differentiation and Functionality

Joanna R. DiSpirito; Hao Shen

J Immunol (2010) 184 (9): 4631–4636.

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CD22 Expression Mediates the Regulatory Functions of Peritoneal B-1a Cells during the Remission Phase of Contact Hypersensitivity Reactions

Hiroko Nakashima; Yasuhito Hamaguchi; Rei Watanabe; Nobuko Ishiura; Yoshihiro Kuwano; Hitoshi Okochi; Yoshimasa Takahashi; Kunihiko Tamaki; Shinichi Sato; Thomas F. Tedder; Manabu Fujimoto

J Immunol (2010) 184 (9): 4637–4645.

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Naive CD4⁺ T Lymphocytes Circulate through Lymphoid Organs To Interact with Endogenous Antigens and Upregulate Their Function

Michio Tomura; Kikuji Itoh; Osami Kanagawa

J Immunol (2010) 184 (9): 4646–4653.

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HLA-B35 Upregulates Endothelin-1 and Downregulates Endothelial Nitric Oxide Synthase via Endoplasmic Reticulum Stress Response in Endothelial Cells

Stefania Lenna; Danyelle M. Townsend; Filemon K. Tan; Bagrat Kapanadze; Malgorzata Markiewicz; Maria Trojanowska; Raffaella Scorza

J Immunol (2010) 184 (9): 4654–4661.

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TLR4 Promotes B Cell Maturation: Independence and Cooperation with B Lymphocyte-Activating Factor

Elize A. Hayashi; Alessandra Granato; Luciana S. Paiva; Álvaro L. Bertho; Maria Bellio; Alberto Nobrega

J Immunol (2010) 184 (9): 4662–4672.

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Notch2 Signaling Is Required for Potent Antitumor Immunity In Vivo

Koji Sugimoto; Yoichi Maekawa; Akiko Kitamura; Jun Nishida; Akemi Koyanagi; Hideo Yagita; Hidefumi Kojima; Shigeru Chiba; Mitsuo Shimada; Koji Yasutomo

J Immunol (2010) 184 (9): 4673–4678.

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Soluble IL-7Rα (sCD127) Inhibits IL-7 Activity and Is Increased in HIV Infection

Angela M. Crawley; Sylvie Faucher; Jonathan B. Angel

J Immunol (2010) 184 (9): 4679–4687.

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IL-4 and TGF-β1 Counterbalance One Another while Regulating Mast Cell Homeostasis

Matthew R. Macey; Jamie L. Sturgill; Johanna K. Morales; Yves T. Falanga; Joshua Morales; Sarah K. Norton; Nitin Yerram; Hoon Shim; Josephine Fernando; Alasdair M. Gifillan; Gregorio Gomez; Lawrence Schwartz; Carole Oskeritzian; Sarah Spiegel; Daniel Conrad; John J. Ryan

J Immunol (2010) 184 (9): 4688–4695.

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Premature Terminal Exhaustion of Friend Virus-Specific Effector CD8⁺ T Cells by Rapid Induction of Multiple Inhibitory Receptors

Shiki Takamura; Sachiyo Tsuji-Kawahara; Hideo Yagita; Hisaya Akiba; Mayumi Sakamoto; Tomomi Chikaishi; Maiko Kato; Masaaki Miyazawa

J Immunol (2010) 184 (9): 4696–4707.

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The Effector T Cell Response to Ryegrass Pollen Is Counterregulated by Simultaneous Induction of Regulatory T Cells

Diana Mittag; Anja Scholzen; Nirupama Varese; Lorraine Baxter; Geza Paukovics; Leonard C. Harrison; Jennifer M. Rolland; Robyn E. O’Hehir

J Immunol (2010) 184 (9): 4708–4716.

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CXC Chemokine Ligand 2 Induced by Receptor Activator of NF-κB Ligand Enhances Osteoclastogenesis

Jeongim Ha; Hyo-Sun Choi; Youngkyun Lee; Hyung-Joo Kwon; Yeong Wook Song; Hong-Hee Kim

J Immunol (2010) 184 (9): 4717–4724.

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Characterizing the Specificity and Cooperation of Aminopeptidases in the Cytosol and Endoplasmic Reticulum during MHC Class I Antigen Presentation

Arron Hearn; Ian A. York; Courtney Bishop; Kenneth L. Rock

J Immunol (2010) 184 (9): 4725–4732.

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Differential but Direct Abolishment of Human Regulatory T Cell Suppressive Capacity by Various TLR2 Ligands

Hans-Heinrich Oberg; Thi Thuy Hoa Ly; Sandra Ussat; Tim Meyer; Dieter Kabelitz; Daniela Wesch

J Immunol (2010) 184 (9): 4733–4740.

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Signal Inhibitory Receptor on Leukocytes-1 Is a Novel Functional Inhibitory Immune Receptor Expressed on Human Phagocytes

Tessa A. M. Steevels; Robert Jan Lebbink; Geertje H. A. Westerlaken; Paul J. Coffer; Linde Meyaard

J Immunol (2010) 184 (9): 4741–4748.

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CD4⁺CD25⁺Foxp3⁺ Regulatory T Cells Optimize Diversity of the Conventional T Cell Repertoire during Reconstitution from Lymphopenia

Colleen J. Winstead; Cavan S. Reilly; James J. Moon; Marc K. Jenkins; Sara E. Hamilton; Stephen C. Jameson; Sing Sing Way; Alexander Khoruts

J Immunol (2010) 184 (9): 4749–4760.

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TAp63 Regulates VLA-4 Expression and Chronic Lymphocytic Leukemia Cell Migration to the Bone Marrow in a CD74-Dependent Manner

Inbal Binsky; Frida Lantner; Valentin Grabovsky; Nurit Harpaz; Lev Shvidel; Alain Berrebi; David M. Goldenberg; Lin Leng; Richard Bucala; Ronen Alon; Michal Haran; Idit Shachar

J Immunol (2010) 184 (9): 4761–4769.

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Dendritic Cells and Stat3 Are Essential for CD137-Induced CD8 T Cell Activation-Induced Cell Death

Benyue Zhang; Yuanyuan Zhang; Liguo Niu; Anthony T. Vella; Robert S. Mittler

J Immunol (2010) 184 (9): 4770–4778.

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Th17 Polarized Cells from Nonobese Diabetic Mice Following Mycobacterial Adjuvant Immunotherapy Delay Type 1 Diabetes

Enayat Nikoopour; Jordan A. Schwartz; Katrina Huszarik; Christian Sandrock; Olga Krougly; Edwin Lee-Chan; Bhagirath Singh

J Immunol (2010) 184 (9): 4779–4788.

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Protective and Pathogenic Roles for B Cells during Systemic Autoimmunity in NZB/W F₁ Mice

Karen M. Haas; Rei Watanabe; Takashi Matsushita; Hiroko Nakashima; Nobuko Ishiura; Hitoshi Okochi; Manabu Fujimoto; Thomas F. Tedder

J Immunol (2010) 184 (9): 4789–4800.

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Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

Rei Watanabe; Nobuko Ishiura; Hiroko Nakashima; Yoshihiro Kuwano; Hitoshi Okochi; Kunihiko Tamaki; Shinichi Sato; Thomas F. Tedder; Manabu Fujimoto

J Immunol (2010) 184 (9): 4801–4809.

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CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

Christian A. Gleissner; Iftach Shaked; Kristina M. Little; Klaus Ley

J Immunol (2010) 184 (9): 4810–4818.

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B Cell-Derived Vascular Endothelial Growth Factor A Promotes Lymphangiogenesis and High Endothelial Venule Expansion in Lymph Nodes

Binita Shrestha; Teruto Hashiguchi; Takashi Ito; Naoki Miura; Kazunori Takenouchi; Yoko Oyama; Ko-ichi Kawahara; Salunya Tancharoen; Yuya Ki-i; Noboru Arimura; Narimasa Yoshinaga; Satoshi Noma; Chandan Shrestha; Takao Nitanda; Shinichi Kitajima; Kimiyoshi Arimura; Masahiro Sato; Taiji Sakamoto; Ikuro Maruyama

J Immunol (2010) 184 (9): 4819–4826.

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Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: Mechanism of Ciprofloxacin-Mediated Immunosuppression

Marcin M. Kamiński; Sven W. Sauer; Claus-Detlev Klemke; Dorothee Süss; Jürgen G. Okun; Peter H. Krammer; Karsten Gülow

J Immunol (2010) 184 (9): 4827–4841.

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Langerhans Cells Prime IL-17–Producing T Cells and Dampen Genital Cytotoxic Responses following Mucosal Immunization

Catherine Hervouet; Carmelo Luci; Nicolas Rol; Déborah Rousseau; Adrien Kissenpfennig; Bernard Malissen; Cecil Czerkinsky; Fabienne Anjuère

J Immunol (2010) 184 (9): 4842–4851.

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Cytokine Secretion Is Distinct from Secretion of Cytotoxic Granules in NK Cells

Esther Reefman; Jason G. Kay; Stephanie M. Wood; Carolin Offenhäuser; Darren L. Brown; Sandrine Roy; Amanda C. Stanley; Pei Ching Low; Anthony P. Manderson; Jennifer L. Stow

J Immunol (2010) 184 (9): 4852–4862.

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Central Nervous System Destruction Mediated by Glutamic Acid Decarboxylase-Specific CD4⁺ T Cells

Amanda R. Burton; Zachary Baquet; George S. Eisenbarth; Roland Tisch; Richard Smeyne; Creg J. Workman; Dario A. A. Vignali

J Immunol (2010) 184 (9): 4863–4870.

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Expression of Cellular FLIP by B Cells Is Required for Their Participation in an Immune Response

Francis Coffey; Tim Manser

J Immunol (2010) 184 (9): 4871–4879.

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IL-17 Amplifies Human Contact Hypersensitivity by Licensing Hapten Nonspecific Th1 Cells to Kill Autologous Keratinocytes

Davide Pennino; Kilian Eyerich; Claudia Scarponi; Teresa Carbone; Stefanie Eyerich; Francesca Nasorri; Simone Garcovich; Claudia Traidl-Hoffmann; Cristina Albanesi; Andrea Cavani

J Immunol (2010) 184 (9): 4880–4888.

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The Role of Skin-Derived Dendritic Cells in CD8⁺ T Cell Priming Following Immunization with Lentivectors

Karina Furmanov; Mazal Elnekave; Dan Lehmann; Bjorn E. Clausen; Darrell N. Kotton; Avi-Hai Hovav

J Immunol (2010) 184 (9): 4889–4897.

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IL-17 Enhancement of the IL-6 Signaling Cascade in Astrocytes

Xiangyu Ma; Stephanie L. Reynolds; Brandi J. Baker; Xingang Li; Etty N. Benveniste; Hongwei Qin

J Immunol (2010) 184 (9): 4898–4906.

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Gene Coexpression Analysis in Single Cells Indicates Lymphomyeloid Copriming in Short-Term Hematopoietic Stem Cells and Multipotent Progenitors

Laetitia Gautreau; Amine Boudil; Valérie Pasqualetto; Lamia Skhiri; Laure Grandin; Marta Monteiro; Jean-Philippe Jais; Sophie Ezine

J Immunol (2010) 184 (9): 4907–4917.

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Keratinocyte-Associated B7-H1 Directly Regulates Cutaneous Effector CD8⁺ T Cell Responses

Patcharee Ritprajak; Masaaki Hashiguchi; Fumihiko Tsushima; Narumon Chalermsarp; Miyuki Azuma

J Immunol (2010) 184 (9): 4918–4925.

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A Steady State of CD4⁺ T Cell Memory Maturation and Activation Is Established during Primary Subtype C HIV-1 Infection

Pholo Maenetje; Catherine Riou; Joseph P. Casazza; David Ambrozak; Brenna Hill; Glenda Gray; Richard A. Koup; Guy de Bruyn; Clive M. Gray

J Immunol (2010) 184 (9): 4926–4935.

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Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

Daphné A. Schmid; Melita B. Irving; Vilmos Posevitz; Michael Hebeisen; Anita Posevitz-Fejfar; J-C. Floyd Sarria; Raquel Gomez-Eerland; Margot Thome; Ton N. M. Schumacher; Pedro Romero; Daniel E. Speiser; Vincent Zoete; Olivier Michielin; Nathalie Rufer

J Immunol (2010) 184 (9): 4936–4946.

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Plasma Cells and Nonplasma B Cells Express Differing IgE Repertoires in Allergic Sensitization

Tobias Rogosch; Sebastian Kerzel; Larisa Sikula; Katrin Gentil; Michael Liebetruth; Karl-Peter Schlingmann; Rolf F. Maier; Michael Zemlin

J Immunol (2010) 184 (9): 4947–4954.

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miR-146a Is Differentially Expressed by Myeloid Dendritic Cell Subsets and Desensitizes Cells to TLR2-Dependent Activation

Jennifer Jurkin; Yvonne M. Schichl; Rene Koeffel; Thomas Bauer; Susanne Richter; Sabine Konradi; Bernhard Gesslbauer; Herbert Strobl

J Immunol (2010) 184 (9): 4955–4965.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Isoallergen Variations Contribute to the Overall Complexity of Effector Cell Degranulation: Effect Mediated through Differentiated IgE Affinity

Lars H. Christensen; Erik Riise; Lærke Bang; Chunqing Zhang; Kaare Lund

J Immunol (2010) 184 (9): 4966–4972.

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A Threonine-Based Targeting Signal in the Human CD1d Cytoplasmic Tail Controls Its Functional Expression

Jianyun Liu; Daniel Shaji; Sungyoo Cho; Wenjun Du; Jacquelyn Gervay-Hague; Randy R. Brutkiewicz

J Immunol (2010) 184 (9): 4973–4981.

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Functional Characterization of the Recombinant Human C1 Inhibitor Serpin Domain: Insights into Heparin Binding

Véronique Rossi; Isabelle Bally; Sarah Ancelet; Yuanyuan Xu; Véronique Frémeaux-Bacchi; Romain R. Vivès; Rabia Sadir; Nicole Thielens; Gérard J. Arlaud

J Immunol (2010) 184 (9): 4982–4989.

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Activating Transcription Factor 3 Is a Positive Regulator of Human IFNG Gene Expression

Sanna Filén; Emmi Ylikoski; Subhash Tripathi; Anne West; Mari Björkman; Joel Nyström; Helena Ahlfors; Eleanor Coffey; Kanury V. S. Rao; Omid Rasool; Riitta Lahesmaa

J Immunol (2010) 184 (9): 4990–4999.

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Functional Analysis of Lyn Kinase A and B Isoforms Reveals Redundant and Distinct Roles in FcεRI-Dependent Mast Cell Activation

Damiana Alvarez-Errico; Yumi Yamashita; Ryo Suzuki; Sandra Odom; Yasuko Furumoto; Toshiyuki Yamashita; Juan Rivera

J Immunol (2010) 184 (9): 5000–5008.

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Multiple RNA Surveillance Mechanisms Cooperate to Reduce the Amount of Nonfunctional Igκ Transcripts

Guillaume Chemin; Aurélien Tinguely; Christophe Sirac; Fabien Lechouane; Sophie Duchez; Michel Cogné; Laurent Delpy

J Immunol (2010) 184 (9): 5009–5017.

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PU.1 Binds to a Distal Regulatory Element That Is Necessary for B Cell-Specific Expression of CIITA

Hyesuk Yoon; Jeremy M. Boss

J Immunol (2010) 184 (9): 5018–5028.

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Estradiol Suppresses NF-κB Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

Amy J. Murphy; Paul M. Guyre; Patricia A. Pioli

J Immunol (2010) 184 (9): 5029–5037.

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IMMUNOGENETICS

Intron-Containing Type I and Type III IFN Coexist in Amphibians: Refuting the Concept That a Retroposition Event Gave Rise to Type I IFNs

Zhitao Qi; Pin Nie; Chris J. Secombes; Jun Zou

J Immunol (2010) 184 (9): 5038–5046.

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Human CD1D Gene Expression Is Regulated by LEF-1 through Distal Promoter Regulatory Elements

Qiao-Yi Chen; Tao Zhang; Seth H. Pincus; Shixiu Wu; David Ricks; Donald Liu; Zhongsheng Sun; Noel Maclaren; Michael S. Lan

J Immunol (2010) 184 (9): 5047–5054.

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Evolution of the Pentraxin Family: The New Entry PTX4

Yeny Martinez de la Torre; Marco Fabbri; Sebastien Jaillon; Antonio Bastone; Manuela Nebuloni; Annunciata Vecchi; Alberto Mantovani; Cecilia Garlanda

J Immunol (2010) 184 (9): 5055–5064.

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SHIP Influences Signals from CD48 and MHC Class I Ligands That Regulate NK Cell Homeostasis, Effector Function, and Repertoire Formation

Nicole R. Fortenbery; Kim H. T. Paraiso; Masaru Taniguchi; Colin Brooks; Leina Ibrahim; William G. Kerr

J Immunol (2010) 184 (9): 5065–5074.

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Nonobese Diabetic Congenic Strain Analysis of Autoimmune Diabetes Reveals Genetic Complexity of the Idd18 Locus and Identifies Vav3 as a Candidate Gene

Heather I. Fraser; Calliope A. Dendrou; Barry Healy; Daniel B. Rainbow; Sarah Howlett; Luc J. Smink; Simon Gregory; Charles A. Steward; John A. Todd; Laurence B. Peterson; Linda S. Wicker

J Immunol (2010) 184 (9): 5075–5084.

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HOST DEFENSE

Impaired Germinal Center Responses and Suppression of Local IgG Production during Intracellular Bacterial Infection

Rachael Racine; Derek D. Jones; Madhumouli Chatterjee; Maura McLaughlin; Katherine C. MacNamara; Gary M. Winslow

J Immunol (2010) 184 (9): 5085–5093.

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Human TLRs 10 and 1 Share Common Mechanisms of Innate Immune Sensing but Not Signaling

Yue Guan; Diana Rose E. Ranoa; Song Jiang; Sarita K. Mutha; Xinyan Li; Jerome Baudry; Richard I. Tapping

J Immunol (2010) 184 (9): 5094–5103.

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Alterations in Ceramide Concentration and pH Determine the Release of Reactive Oxygen Species by Cftr-Deficient Macrophages on Infection

Yang Zhang; Xiang Li; Heike Grassmé; Gerd Döring; Erich Gulbins

J Immunol (2010) 184 (9): 5104–5111.

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Disordered Lymphoid Purine Metabolism Contributes to the Pathogenesis of Persistent Borrelia garinii Infection in Mice

Gennady G. Yegutkin; Jukka Hytönen; Sergei S. Samburski; Heta Yrjänäinen; Sirpa Jalkanen; Matti K. Viljanen

J Immunol (2010) 184 (9): 5112–5120.

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Helicobacter pylori-Induced Th17 Responses Modulate Th1 Cell Responses, Benefit Bacterial Growth, and Contribute to Pathology in Mice

J Immunol (2010) 184 (9): 5121–5129.

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Induction of TGF-β1, Not Regulatory T Cells, Impairs Antiviral Immunity in the Lung following Bone Marrow Transplant

Stephanie M. Coomes; Carol A. Wilke; Thomas A. Moore; Bethany B. Moore

J Immunol (2010) 184 (9): 5130–5140.

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Francisella Acid Phosphatases Inactivate the NADPH Oxidase in Human Phagocytes

Nrusingh P. Mohapatra; Shilpa Soni; Murugesan V. S. Rajaram; Pham My-Chan Dang; Tom J. Reilly; Jamel El-Benna; Corey D. Clay; Larry S. Schlesinger; John S. Gunn

J Immunol (2010) 184 (9): 5141–5150.

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Cell-Intrinsic Defects in the Proliferative Response of Antiviral Memory CD8 T Cells in Aged Mice upon Secondary Infection

Vilma Decman; Brian J. Laidlaw; Lauren J. DiMenna; Sarah Abdulla; Krystyna Mozdzanowska; Jan Erikson; Hildegund C. J. Ertl; E. John Wherry

J Immunol (2010) 184 (9): 5151–5159.

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Suppression of Host Innate Immune Response by Burkholderia pseudomallei through the Virulence Factor TssM

Kai Soo Tan; Yahua Chen; Yaw-Chyn Lim; Gek-Yen Gladys Tan; Yichun Liu; Yan-Ting Lim; Paul MacAry; Yunn-Hwen Gan

J Immunol (2010) 184 (9): 5160–5171.

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Activation of Naive NK Cells in Response to Listeria monocytogenes Requires IL-18 and Contact with Infected Dendritic Cells

Jessica Humann; Laurel L. Lenz

J Immunol (2010) 184 (9): 5172–5178.

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IFN Regulatory Factor-1 Bypasses IFN-Mediated Antiviral Effects through Viperin Gene Induction

Anja Stirnweiss; Antje Ksienzyk; Katjana Klages; Ulfert Rand; Martina Grashoff; Hansjörg Hauser; Andrea Kröger

J Immunol (2010) 184 (9): 5179–5185.

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Kaposi’s Sarcoma-Associated Herpesvirus K3 and K5 Proteins Block Distinct Steps in Transendothelial Migration of Effector Memory CD4+ T Cells by Targeting Different Endothelial Proteins

Thomas D. Manes; Simon Hoer; William A. Muller; Paul J. Lehner; Jordan S. Pober

J Immunol (2010) 184 (9): 5186–5192.

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Caspases in Virus-Infected Cells Contribute to Recognition by CD8⁺ T Lymphocytes

Daniel López; Margarita García-Calvo; Geoffrey L. Smith; Margarita Del Val

J Immunol (2010) 184 (9): 5193–5199.

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The Protein Moiety of Brucella abortus Outer Membrane Protein 16 Is a New Bacterial Pathogen-Associated Molecular Pattern That Activates Dendritic Cells In Vivo, Induces a Th1 Immune Response, and Is a Promising Self-Adjuvanting Vaccine against Systemic and Oral Acquired Brucellosis

Karina A. Pasquevich; Clara García Samartino; Lorena M. Coria; Silvia M. Estein; Astrid Zwerdling; Andrés E. Ibañez; Paula Barrionuevo; Fernanda Souza de Oliveira; Natalia Barbosa Carvalho; Julia Borkowski; Sergio Costa Oliveira; Heribert Warzecha; Guillermo H. Giambartolomei; Juliana Cassataro

J Immunol (2010) 184 (9): 5200–5212.

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B Cells Have Distinct Roles in Host Protection against Different Nematode Parasites

Qian Liu; Timothy Kreider; Scott Bowdridge; Zhugong Liu; Youngmia Song; Andrew G. Gaydo; Joseph F. Urban, Jr.; William C. Gause

J Immunol (2010) 184 (9): 5213–5223.

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CCR5 Dictates the Equilibrium of Proinflammatory IL-17⁺ and Regulatory Foxp3⁺ T Cells in Fungal Infection

Danielle N. Kroetz; George S. Deepe, Jr.

J Immunol (2010) 184 (9): 5224–5231.

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INFLAMMATION

Production of Vascular Endothelial Growth Factors from Human Lung Macrophages Induced by Group IIA and Group X Secreted Phospholipases A₂

Francescopaolo Granata; Annunziata Frattini; Stefania Loffredo; Rosaria I. Staiano; Angelica Petraroli; Domenico Ribatti; Rob Oslund; Michael H. Gelb; Gerard Lambeau; Gianni Marone; Massimo Triggiani

J Immunol (2010) 184 (9): 5232–5241.

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Intercellular Adhesion Molecule-1 Enrichment near Tricellular Endothelial Junctions Is Preferentially Associated with Leukocyte Transmigration and Signals for Reorganization of These Junctions To Accommodate Leukocyte Passage

Ronen Sumagin; Ingrid H. Sarelius

J Immunol (2010) 184 (9): 5242–5252.

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Hypertonicity-Induced Expression of Monocyte Chemoattractant Protein-1 through a Novel Cis-Acting Element and MAPK Signaling Pathways

Ryoji Kojima; Hajime Taniguchi; Aya Tsuzuki; Kanako Nakamura; Yumi Sakakura; Mikio Ito

J Immunol (2010) 184 (9): 5253–5262.

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Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1α, and TNF-α Recapitulates Some Features of Psoriasis

Karline Guilloteau; Isabelle Paris; Nathalie Pedretti; Katia Boniface; Franck Juchaux; Vincent Huguier; Gerard Guillet; François-Xavier Bernard; Jean-Claude Lecron; Franck Morel

J Immunol (2010) 184 (9): 5263–5270.

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Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

Ulrich Schingnitz; Katherine Hartmann; Christopher F. MacManus; Tobias Eckle; Stephanie Zug; Sean P. Colgan; Holger K. Eltzschig

J Immunol (2010) 184 (9): 5271–5279.

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Docosahexaenoic Acid-Enriched Fish Oil Attenuates Kidney Disease and Prolongs Median and Maximal Life Span of Autoimmune Lupus-Prone Mice

Ganesh V. Halade; Md Mizanur Rahman; Arunabh Bhattacharya; Jeffrey L. Barnes; Bysani Chandrasekar; Gabriel Fernandes

J Immunol (2010) 184 (9): 5280–5286.

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Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF-κB Signaling

Claudia Toma; Naomi Higa; Yukiko Koizumi; Noboru Nakasone; Yasunori Ogura; Andrea J. McCoy; Luigi Franchi; Satoshi Uematsu; Junji Sagara; Shun’ichiro Taniguchi; Hiroko Tsutsui; Shizuo Akira; Jürg Tschopp; Gabriel Núñez; Toshihiko Suzuki

J Immunol (2010) 184 (9): 5287–5297.

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Selective Inhibition of JAK1 and JAK2 Is Efficacious in Rodent Models of Arthritis: Preclinical Characterization of INCB028050

J Immunol (2010) 184 (9): 5298–5307.

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TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation

Hang Zhao; Shaw-Wei Leu; Liyun Shi; Rejmon Dedaj; Gaofeng Zhao; Hari G. Garg; Lianjun Shen; Egil Lien; Katherine A. Fitzgerald; Aviva Shiedlin; Huahao Shen; Deborah A. Quinn; Charles A. Hales

J Immunol (2010) 184 (9): 5308–5314.

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Chemerin Peptides Promote Phagocytosis in a ChemR23- and Syk-Dependent Manner

Jenna L. Cash; Annabel R. Christian; David R. Greaves

J Immunol (2010) 184 (9): 5315–5324.

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Fas-Activated Serine/Threonine Phosphoprotein Promotes Immune-Mediated Pulmonary Inflammation

Maria Simarro; Giorgio Giannattasio; Miguel A. De la Fuente; Charaf Benarafa; Kulandayan K. Subramanian; Rumey Ishizawar; Barbara Balestrieri; Emma M. Andersson; Hongbo R. Luo; Antonio Orduña; Joshua Boyce; Paul Anderson

J Immunol (2010) 184 (9): 5325–5332.

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IFN-γ Promotes Complement Expression and Attenuates Amyloid Plaque Deposition in Amyloid β Precursor Protein Transgenic Mice

Paramita Chakrabarty; Carolina Ceballos-Diaz; Amanda Beccard; Christopher Janus; Dennis Dickson; Todd E. Golde; Pritam Das

J Immunol (2010) 184 (9): 5333–5343.

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CLINICAL IMMUNOLOGY

Intragraft Th17 Infiltrate Promotes Lymphoid Neogenesis and Hastens Clinical Chronic Rejection

Clémence Deteix; Valérie Attuil-Audenis; Aurélie Duthey; Natacha Patey; Brigitte McGregor; Valérie Dubois; Giuseppina Caligiuri; Stéphanie Graff-Dubois; Emmanuel Morelon; Olivier Thaunat

J Immunol (2010) 184 (9): 5344–5351.

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Transgenic Expression of TGF-β on Thyrocytes Inhibits Development of Spontaneous Autoimmune Thyroiditis and Increases Regulatory T Cells in Thyroids of NOD.H-2h4 Mice

Shiguang Yu; Yujiang Fang; Gordon C. Sharp; Helen Braley-Mullen

J Immunol (2010) 184 (9): 5352–5359.

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Treatment Failure of a TLR-7 Agonist Occurs Due to Self-Regulation of Acute Inflammation and Can Be Overcome by IL-10 Blockade

Hailing Lu; Wolfgang M. Wagner; Ekram Gad; Yi Yang; Hangjun Duan; Lynn M. Amon; Nathaniel Van Denend; Emily R. Larson; Amy Chang; Helena Tufvesson; Mary L. Disis

J Immunol (2010) 184 (9): 5360–5367.

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An Imbalance of Two Functionally and Phenotypically Different Subsets of Plasmacytoid Dendritic Cells Characterizes the Dysfunctional Immune Regulation in Multiple Sclerosis

Nicholas Schwab; Alla L. Zozulya; Bernd C. Kieseier; Klaus V. Toyka; Heinz Wiendl

J Immunol (2010) 184 (9): 5368–5374.

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At Homeostasis Filarial Infections Have Expanded Adaptive T Regulatory but Not Classical Th2 Cells

Simon Metenou; Benoit Dembele; Siaka Konate; Housseini Dolo; Siaka Y. Coulibaly; Yaya I. Coulibaly; Abdallah A. Diallo; Lamine Soumaoro; Michel E. Coulibaly; Dramane Sanogo; Salif S. Doumbia; Sekou F. Traoré; Siddhartha Mahanty; Amy Klion; Thomas B. Nutman

J Immunol (2010) 184 (9): 5375–5382.

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Interdisciplinary Analysis of HIV-Specific CD8⁺ T Cell Responses against Variant Epitopes Reveals Restricted TCR Promiscuity

Ilka Hoof; Carina L. Pérez; Marcus Buggert; Rasmus K. L. Gustafsson; Morten Nielsen; Ole Lund; Annika C. Karlsson

J Immunol (2010) 184 (9): 5383–5391.

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Ezrin, Maspin, Peroxiredoxin 2, and Heat Shock Protein 27: Potential Targets of a Streptococcal-Induced Autoimmune Response in Psoriasis

Petra Besgen; Paul Trommler; Sigrid Vollmer; Joerg Christoph Prinz

J Immunol (2010) 184 (9): 5392–5402.

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Identification, Recombinant Expression, and Characterization of the 100 kDa High Molecular Weight Hymenoptera Venom Allergens Api m 5 and Ves v 3

Simon Blank; Henning Seismann; Benjamin Bockisch; Ingke Braren; Liliana Cifuentes; Mareike McIntyre; Dana Rühl; Johannes Ring; Reinhard Bredehorst; Markus W. Ollert; Thomas Grunwald; Edzard Spillner

J Immunol (2010) 184 (9): 5403–5413.

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CORRECTIONS

Predominant expression of CCL2 at the tumor site of prostate cancer patients directs a selective loss of immunological tolerance to CCL2 that could be amplified in a beneficial manner

Liat Izhak; Gizi Wildbaum; Weinberg Uri; Yuval Shaked; Jennifer Alami; Daniel Dumont; Daniel Dumont; Avi Stein; Nathan Karin

J Immunol (2010) 184 (9): 5414.

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Contribution of mutation, recombination, and gene conversion to chicken Mhc-B haplotype diversity

Kazuyoshi Hosomichi; Marcia M. Miller; Ronald M. Goto; Yujun Wang; Shingo Suzuki; Jerzy K. Kulski; Masahide Nishibori; Hidetoshi Inoko; Kei Hanzawa; Takashi Shiina

J Immunol (2010) 184 (9): 5415.

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Cover Image

Cover Image

On the cover: Silver staining of peripheral lymph nodes from Borrelia garinii-infected C3H/He mice. Along with the fine reticular architecture of the lymph node body, which appears brown in color, darker silver impregnated spirochete-like elements can be seen in the infected lymphoid tissues (as easily visualized at higher magnification on inset). Yegutkin, G. G., J. Hytönen, S. S. Samburski, H. Yrjänäinen, S. Jalkanen, and M. K. Viljanen. 2010. Disordered lymphoid purine metabolism contributes to the pathogenesis of persistent Borrelia garinii infection in mice. J. Immunol. 184: 5112–5120.
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