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Issues
1 July 2010
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
TLR4 Signaling Inhibitory Pathway Induced by Green Tea Polyphenol Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor
J Immunol (2010) 185 (1): 33–45.
Mechanisms of IL-12 Synthesis by Human Dendritic Cells Treated with the Chemical Sensitizer NiSO4
J Immunol (2010) 185 (1): 89–98.
The Adaptor Molecule Act1 Regulates BAFF Responsiveness and Self-Reactive B Cell Selection during Transitional B Cell Maturation
J Immunol (2010) 185 (1): 99–109.
An Autoantigen-Specific, Highly Restricted T Cell Repertoire Infiltrates the Arthritic Joints of Mice in an HLA-DR1 Humanized Mouse Model of Autoimmune Arthritis
Zhaohui Qian; Kary A. Latham; Karen B. Whittington; David C. Miller; David D. Brand; Edward F. Rosloniec
J Immunol (2010) 185 (1): 110–118.
Lipopolysaccharide-Mediated Mast Cell Activation Induces IFN-γ Secretion by NK Cells
J Immunol (2010) 185 (1): 119–125.
Naturally Activated Vγ4 γδ T Cells Play a Protective Role in Tumor Immunity through Expression of Eomesodermin
Weifeng He; Jianlei Hao; Siyuan Dong; Yunfei Gao; Jian Tao; Hongbo Chi; Richard Flavell; Rebecca L. O’Brien; Willi K. Born; Joseph Craft; Jihong Han; Puyue Wang; Liqing Zhao; Jun Wu; Zhinan Yin
J Immunol (2010) 185 (1): 126–133.
High Expression of the Ectonucleotidase CD39 on T Cells from the Inflamed Site Identifies Two Distinct Populations, One Regulatory and One Memory T Cell Population
Halima Moncrieffe; Kiran Nistala; Yasmine Kamhieh; Jamie Evans; Ayad Eddaoudi; Simon Eaton; Lucy R. Wedderburn
J Immunol (2010) 185 (1): 134–143.
Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function
Idil Aktan; Alan Chant; Zachary D. Borg; David E. Damby; Paige C. Leenstra; Graham W. G. Lilley; Joseph Petty; Benjamin T. Suratt; Cory Teuscher; Edward K. Wakeland; Matthew E. Poynter; Jonathan E. Boyson
J Immunol (2010) 185 (1): 144–156.
Increased Targeting of Donor Switch Region and IgE in Sγ1-Deficient B Cells
Shahram Misaghi; Christopher S. Garris; Yonglian Sun; Allen Nguyen; Juan Zhang; Andrew Sebrell; Kate Senger; Donghong Yan; Maria N. Lorenzo; Sherry Heldens; Wyne P. Lee; Min Xu; Jiansheng Wu; Laura DeForge; Tao Sai; Vishva M. Dixit; Ali A. Zarrin
J Immunol (2010) 185 (1): 166–173.
CD49d Is a New Marker for Distinct Myeloid-Derived Suppressor Cell Subpopulations in Mice
J Immunol (2010) 185 (1): 203–210.
T Cell and APC Dynamics In Situ Control the Outcome of Vaccination
Kamal M. Khanna; David A. Blair; Anthony T. Vella; Stephen J. McSorley; Sandip K. Datta; Leo Lefrançois
J Immunol (2010) 185 (1): 239–252.
Plasticity of Invariant NKT Cell Regulation of Allergic Airway Disease Is Dependent on IFN-γ Production
Hiroyuki Matsuda; Katsuyuki Takeda; Toshiyuki Koya; Masakazu Okamoto; Yoshiki Shiraishi; Nobuaki Miyahara; Azzeddine Dakhama; Jennifer L. Matsuda; Laurent Gapin; Erwin W. Gelfand
J Immunol (2010) 185 (1): 253–262.
Early Signals during CD8+ T Cell Priming Regulate the Generation of Central Memory Cells
J Immunol (2010) 185 (1): 263–272.
Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus
J Immunol (2010) 185 (1): 284–293.
A Role for Lysosomal-Associated Protein Transmembrane 5 in the Negative Regulation of Surface B Cell Receptor Levels and B Cell Activation
J Immunol (2010) 185 (1): 294–301.
Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype
J Immunol (2010) 185 (1): 302–312.
Distinct Roles of Adenylyl Cyclase VII in Regulating the Immune Responses in Mice
Biyan Duan; Richard Davis; Eva L. Sadat; Julie Collins; Paul C. Sternweis; Dorothy Yuan; Lily I. Jiang
J Immunol (2010) 185 (1): 335–344.
Regulation of Cytokine-Driven Functional Differentiation of CD8 T Cells by Suppressor of Cytokine Signaling 1 Controls Autoimmunity and Preserves Their Proliferative Capacity toward Foreign Antigens
Sheela Ramanathan; Stephanie Dubois; Julien Gagnon; Chantal Leblanc; Sanjeev Mariathasan; Gerardo Ferbeyre; Robert Rottapel; Pamela S. Ohashi; Subburaj Ilangumaran
J Immunol (2010) 185 (1): 357–366.
Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms
Jane Oliaro; Vanessa Van Ham; Faruk Sacirbegovic; Anupama Pasam; Ze’ev Bomzon; Kim Pham; Mandy J. Ludford-Menting; Nigel J. Waterhouse; Michael Bots; Edwin D. Hawkins; Sally V. Watt; Leonie A. Cluse; Chris J. P. Clarke; David J. Izon; John T. Chang; Natalie Thompson; Min Gu; Ricky W. Johnstone; Mark J. Smyth; Patrick O. Humbert; Steven L. Reiner; Sarah M. Russell
J Immunol (2010) 185 (1): 367–375.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Crystal Structure of Bovine CD1b3 with Endogenously Bound Ligands
Enrico Girardi; Jing Wang; Thien-Thi Mac; Cees Versluis; Veemal Bhowruth; Gurdyal Besra; Albert J.R. Heck; Ildiko Van Rhijn; Dirk M. Zajonc
J Immunol (2010) 185 (1): 376–386.
Dicer-Dependent MicroRNAs Control Maturation, Function, and Maintenance of Langerhans Cells In Vivo
J Immunol (2010) 185 (1): 400–409.
Notch Target Gene Deregulation and Maintenance of the Leukemogenic Phenotype Do Not Require RBP-Jκ in Ikaros Null Mice
J Immunol (2010) 185 (1): 410–417.
IMMUNOGENETICS
Combined Genotypic and Phenotypic Killer Cell Ig-Like Receptor Analyses Reveal KIR2DL3 Alleles Displaying Unexpected Monoclonal Antibody Reactivity: Identification of the Amino Acid Residues Critical for Staining
Michela Falco; Elisa Romeo; Stefania Marcenaro; Stefania Martini; Massimo Vitale; Cristina Bottino; Maria Cristina Mingari; Lorenzo Moretta; Alessandro Moretta; Daniela Pende
J Immunol (2010) 185 (1): 433–441.
HOST DEFENSE
Double-Stranded RNA Exacerbates Pulmonary Allergic Reaction through TLR3: Implication of Airway Epithelium and Dendritic Cells
David Torres; Audrey Dieudonné; Bernhard Ryffel; Eva Vilain; Mustapha Si-Tahar; Muriel Pichavant; Philippe Lassalle; François Trottein; Philippe Gosset
J Immunol (2010) 185 (1): 451–459.
Chicken TLR21 Is an Innate CpG DNA Receptor Distinct from Mammalian TLR9
J Immunol (2010) 185 (1): 460–467.
Myeloid PTEN Promotes Inflammation but Impairs Bactericidal Activities during Murine Pneumococcal Pneumonia
Gernot Schabbauer; Ulrich Matt; Philipp Günzl; Joanna Warszawska; Tanja Furtner; Eva Hainzl; Immanuel Elbau; Ildiko Mesteri; Bianca Doninger; Bernd R. Binder; Sylvia Knapp
J Immunol (2010) 185 (1): 468–476.
Herpes Simplex Virus Infects Skin γδ T Cells before Langerhans Cells and Impedes Migration of Infected Langerhans Cells by Inducing Apoptosis and Blocking E-Cadherin Downregulation
Franz K. Puttur; Marian A. Fernandez; Rose White; Ben Roediger; Anthony L. Cunningham; Wolfgang Weninger; Cheryl A. Jones
J Immunol (2010) 185 (1): 477–487.
Identification of an Important Immunological Difference between Virulent Varicella-Zoster Virus and Its Avirulent Vaccine: Viral Disruption of Dendritic Cell Instruction
Cindy Gutzeit; Martin J. Raftery; Matthias Peiser; Karsten B. Tischer; Martina Ulrich; Melanie Eberhardt; Eggert Stockfleth; Thomas Giese; Andreas Sauerbrei; Craig T. Morita; Günther Schönrich
J Immunol (2010) 185 (1): 488–497.
HIV-Specific IL-21 Producing CD4+ T Cells Are Induced in Acute and Chronic Progressive HIV Infection and Are Associated with Relative Viral Control
Feng Yun Yue; Calvin Lo; Ali Sakhdari; Erika Yue Lee; Colin M. Kovacs; Erika Benko; Jun Liu; Haihan Song; R. Brad Jones; Prameet Sheth; Duncan Chege; Rupert Kaul; Mario A. Ostrowski
J Immunol (2010) 185 (1): 498–506.
An Evaluation of the Role of Properdin in Alternative Pathway Activation on Neisseria meningitidis and Neisseria gonorrhoeae
J Immunol (2010) 185 (1): 507–516.
IL-7–Dependent B Lymphocytes Are Essential for the Anti-polysaccharide Response and Protective Immunity to Streptococcus pneumoniae
J Immunol (2010) 185 (1): 525–531.
CD11c+ Dendritic Cells and B Cells Contribute to the Tumoricidal Activity of Anti-DR5 Antibody Therapy in Established Tumors
Nicole M. Haynes; Edwin D. Hawkins; Ming Li; Nicole M. McLaughlin; Günter J. Hämmerling; Reto Schwendener; Astar Winoto; Allen Wensky; Hideo Yagita; Kazuyoshi Takeda; Michael H. Kershaw; Phillip K. Darcy; Mark J. Smyth
J Immunol (2010) 185 (1): 532–541.
A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation
Balázs Csóka; Zoltán H. Németh; Peter Rosenberger; Holger K. Eltzschig; Zoltán Spolarics; Pál Pacher; Zsolt Selmeczy; Balázs Koscsó; Leonóra Himer; E. Sylvester Vizi; Michael R. Blackburn; Edwin A. Deitch; György Haskó
J Immunol (2010) 185 (1): 542–550.
CD40 Expression Levels Modulate Regulatory T Cells in Leishmania donovani Infection
J Immunol (2010) 185 (1): 551–559.
INFLAMMATION
NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice
J Immunol (2010) 185 (1): 569–577.
Protein Tyrosine Nitration of Aldolase in Mast Cells: A Plausible Pathway in Nitric Oxide-Mediated Regulation of Mast Cell Function
J Immunol (2010) 185 (1): 578–587.
Nicotine Inhibits FcεRI-Induced Cysteinyl Leukotrienes and Cytokine Production without Affecting Mast Cell Degranulation Through α7/α9/α10-Nicotinic Receptors
Neerad C. Mishra; Jules Rir-sima-ah; R. Thomas Boyd; Shashi P. Singh; Sravanthi Gundavarapu; Raymond J. Langley; Seddigheh Razani-Boroujerdi; Mohan L. Sopori
J Immunol (2010) 185 (1): 588–596.
TLR2- and Nucleotide-Binding Oligomerization Domain 2-Dependent Krüppel-Like Factor 2 Expression Downregulates NF-κB–Related Gene Expression
Janine Zahlten; Robert Steinicke; Bastian Opitz; Julia Eitel; Philippe Dje N’Guessan; Maya Vinzing; Martin Witzenrath; Bernd Schmeck; Sven Hammerschmidt; Norbert Suttorp; Stefan Hippenstiel
J Immunol (2010) 185 (1): 597–604.
α-Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1
Eun-Jung Lee; Moon-Sook Woo; Pyong-Gon Moon; Moon-Chang Baek; In-Young Choi; Won-Ki Kim; Eunsung Junn; Hee-Sun Kim
J Immunol (2010) 185 (1): 615–623.
Mouse Mast Cell Protease-4 Deteriorates Renal Function by Contributing to Inflammation and Fibrosis in Immune Complex-Mediated Glomerulonephritis
Lisa Scandiuzzi; Walid Beghdadi; Eric Daugas; Magnus Åbrink; Neeraj Tiwari; Cristiana Brochetta; Julien Claver; Nassim Arouche; Xingxing Zang; Marina Pretolani; Renato C. Monteiro; Gunnar Pejler; Ulrich Blank
J Immunol (2010) 185 (1): 624–633.
Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome
J Immunol (2010) 185 (1): 634–641.
Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility
Graziella Solinas; Silvia Schiarea; Manuela Liguori; Marco Fabbri; Samantha Pesce; Luca Zammataro; Fabio Pasqualini; Manuela Nebuloni; Chiara Chiabrando; Alberto Mantovani; Paola Allavena
J Immunol (2010) 185 (1): 642–652.
Ig-Free Light Chains Play a Crucial Role in Murine Mast Cell-Dependent Colitis and Are Associated with Human Inflammatory Bowel Diseases
Anneke Rijnierse; Frank A. Redegeld; Bart R. Blokhuis; Maurice W. Van der Heijden; Anje A. Te Velde; Inge Pronk; Daniel W. Hommes; Frans P. Nijkamp; Andries S. Koster; Aletta D. Kraneveld
J Immunol (2010) 185 (1): 653–659.
Human Th17 Cells Comprise Heterogeneous Subsets Including IFN-γ–Producing Cells with Distinct Properties from the Th1 Lineage
Katia Boniface; Wendy M. Blumenschein; Katherine Brovont-Porth; Mandy J. McGeachy; Beth Basham; Bela Desai; Robert Pierce; Terrill K. McClanahan; Svetlana Sadekova; René de Waal Malefyt
J Immunol (2010) 185 (1): 679–687.
CLINICAL IMMUNOLOGY
Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema
Sanja Cicko; Monica Lucattelli; Tobias Müller; Marek Lommatzsch; Giovanna De Cunto; Silvia Cardini; William Sundas; Melanine Grimm; Robert Zeiser; Thorsten Dürk; Gernot Zissel; Jean-Marie Boeynaems; Stephan Sorichter; Davide Ferrari; Francesco Di Virgilio; J. Christian Virchow; Giuseppe Lungarella; Marco Idzko
J Immunol (2010) 185 (1): 688–697.
Intratumoral Neoadjuvant Immunotherapy Using IL-12 and Dendritic Cells Is an Effective Strategy To Control Recurrence of Murine Hepatocellular Carcinoma in Immunosuppressed Mice
Hiroto Kayashima; Takeo Toshima; Shinji Okano; Akinobu Taketomi; Noboru Harada; Yo-ichi Yamashita; Yukihiro Tomita; Ken Shirabe; Yoshihiko Maehara
J Immunol (2010) 185 (1): 698–708.
Mast Cell Stabilization Improves Survival by Preventing Apoptosis in Sepsis
J Immunol (2010) 185 (1): 709–716.
Chronic Rejection Triggers the Development of an Aggressive Intragraft Immune Response through Recapitulation of Lymphoid Organogenesis
Olivier Thaunat; Natacha Patey; Giuseppina Caligiuri; Chantal Gautreau; Maria Mamani-Matsuda; Yahia Mekki; Marie-Caroline Dieu-Nosjean; Gérard Eberl; René Ecochard; Jean-Baptiste Michel; Stéphanie Graff-Dubois; Antonino Nicoletti
J Immunol (2010) 185 (1): 717–728.
Conformation-Dependent High-Affinity Monoclonal Antibodies to Prion Proteins
Larry H. Stanker; Ana V. Serban; Elisa Cleveland; Robert Hnasko; Azucena Lemus; Jiri Safar; Stephen J. DeArmond; Stanley B. Prusiner
J Immunol (2010) 185 (1): 729–737.
TLR4-Mediated Sensing of Campylobacter jejuni by Dendritic Cells Is Determined by Sialylation
Mark L. Kuijf; Janneke N. Samsom; Wouter van Rijs; Marieke Bax; Ruth Huizinga; Astrid P. Heikema; Pieter A. van Doorn; Alex van Belkum; Yvette van Kooyk; Peter C. Burgers; Theo M. Luider; Hubert P. Endtz; Edward E. S. Nieuwenhuis; Bart C. Jacobs
J Immunol (2010) 185 (1): 748–755.
Fluctuation of Peripheral Blood T, B, and NK Cells during a Menstrual Cycle of Normal Healthy Women
Sungki Lee; Jeeyun Kim; Byungwoo Jang; Sungeun Hur; Unsuk Jung; Kihyun Kil; Baegju Na; Millina Lee; Youngmin Choi; Atsushi Fukui; Alice Gilman-Sachs; Joanne Y. Kwak-Kim
J Immunol (2010) 185 (1): 756–762.
A Novel Strategy To Reduce the Immunogenicity of Biological Therapies
Jennifer Somerfield; Grant A. Hill-Cawthorne; Andrew Lin; Michael S. Zandi; Claire McCarthy; Joanne L. Jones; Michael Willcox; David Shaw; Sara A. J. Thompson; Alastair S. Compston; Geoff Hale; Herman Waldmann; Alasdair J. Coles
J Immunol (2010) 185 (1): 763–768.
CORRECTIONS
Correction: Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes
J Immunol (2010) 185 (1): 769.
Correction: Fas Apoptosis Inhibitory Molecule Enhances CD40 Signaling in B Cells and Augments the Plasma Cell Compartment
J Immunol (2010) 185 (1): 771.
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Cover Image
Cover Image
On the cover: Side view of the Ag-binding groove of bovine CD1b3 (in gray) and human CD1b (in cyan). The bound bovine CD1b3 ligands phosphatidylcholine and phosphatidylethanolamine (in yellow and orange, respectively) are shown in comparison with the human CD1b ligands phosphatidylcholine and a spacer molecule (both in cyan). Girardi, E., J. Wang, T.-T. Mac, C. Versluis, V. Bhowruth, G. Besra, A. J. R. Heck, I. Van Rhijn, and D. M. Zajonc. 2010. Crystal structure of bovine CD1b3 with endogenously bound ligands. J. Immunol. 185: 376–386.
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