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Issues
1 January 2011
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
The Influence of Excessive IL-6 Production In Vivo on the Development and Function of Foxp3+ Regulatory T Cells
Minoru Fujimoto; Mayumi Nakano; Fumitaka Terabe; Hirohisa Kawahata; Tomoharu Ohkawara; Yongmei Han; Barry Ripley; Satoshi Serada; Teppei Nishikawa; Akihiro Kimura; Shintaro Nomura; Tadamitsu Kishimoto; Tetsuji Naka
J Immunol (2011) 186 (1): 32–40.
Interactions of NK Cell Receptor KIR3DL1*004 with Chaperones and Conformation-Specific Antibody Reveal a Functional Folded State As Well As Predominant Intracellular Retention
Sabrina B. Taner; Marcelo J. Pando; Allison Roberts; Jennifer Schellekens; Steven G. E. Marsh; Karl-Johan Malmberg; Peter Parham; Frances M. Brodsky
J Immunol (2011) 186 (1): 62–72.
Exosomes Containing Glycoprotein 350 Released by EBV-Transformed B Cells Selectively Target B Cells through CD21 and Block EBV Infection In Vitro
Helen Vallhov; Cindy Gutzeit; Sara M. Johansson; Noémi Nagy; Mandira Paul; Qin Li; Sherree Friend; Thaddeus C. George; Eva Klein; Annika Scheynius; Susanne Gabrielsson
J Immunol (2011) 186 (1): 73–82.
IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression
Kathrin Eller; Dominik Wolf; Julia M. Huber; Martin Metz; Gert Mayer; Andrew N. J. McKenzie; Marcus Maurer; Alexander R. Rosenkranz; Anna M. Wolf
J Immunol (2011) 186 (1): 83–91.
Profiling of CD4+ T Cells with Epigenetic Immune Lineage Analysis
Peter C. J. Janson; Ludvig Bernt Linton; Emma Ahlén Bergman; Per Marits; Michael Eberhardson; Fredrik Piehl; Vivianne Malmström; Ola Winqvist
J Immunol (2011) 186 (1): 92–102.
Targeting the CXCR4–CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1
Paolo Fiorina; Mollie Jurewicz; Andrea Vergani; Alessandra Petrelli; Michele Carvello; Francesca D’Addio; Jonathan G. Godwin; Kenneth Law; Erxi Wu; Ze Tian; Gebhard Thoma; Jiri Kovarik; Stefano La Rosa; Carlo Capella; Scott Rodig; Hans-Guenter Zerwes; Mohamed H. Sayegh; Reza Abdi
J Immunol (2011) 186 (1): 121–131.
The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of Inflammation
Femke Baeke; Hannelie Korf; Lut Overbergh; Annemieke Verstuyf; Lieven Thorrez; Leentje Van Lommel; Mark Waer; Frans Schuit; Conny Gysemans; Chantal Mathieu
J Immunol (2011) 186 (1): 132–142.
A Marked Reduction in Priming of Cytotoxic CD8+ T Cells Mediated by Stress-Induced Glucocorticoids Involves Multiple Deficiencies in Cross-Presentation by Dendritic Cells
John T. Hunzeker; Michael D. Elftman; Jennifer C. Mellinger; Michael F. Princiotta; Robert H. Bonneau; Mary E. Truckenmiller; Christopher C. Norbury
J Immunol (2011) 186 (1): 183–194.
Sepsis Induces Early Alterations in Innate Immunity That Impact Mortality to Secondary Infection
Matthew J. Delano; Terri Thayer; Sonia Gabrilovich; Kindra M. Kelly-Scumpia; Robert D. Winfield; Philip O. Scumpia; Alex G. Cuenca; Elizabeth Warner; Shannon M. Wallet; Mark A. Wallet; Kerri A. O’Malley; Reuben Ramphal; Michael Clare-Salzer; Philip A. Efron; Clayton E. Mathews; Lyle L. Moldawer
J Immunol (2011) 186 (1): 195–202.
Graft-versus-Host Disease Is Independent of Innate Signaling Pathways Triggered by Pathogens in Host Hematopoietic Cells
Hongmei Li; Catherine Matte-Martone; Hung Sheng Tan; Srividhya Venkatesan; Jennifer McNiff; Anthony J. Demetris; Dhanpat Jain; Fadi Lakkis; David Rothstein; Warren D. Shlomchik
J Immunol (2011) 186 (1): 230–241.
Bcl6 Is Required for the Development of Mouse CD4+ and CD8α+ Dendritic Cells
Hiromi Ohtsuka; Akemi Sakamoto; Jing Pan; Sumina Inage; Satoshi Horigome; Hirohito Ichii; Masafumi Arima; Masahiko Hatano; Seiji Okada; Takeshi Tokuhisa
J Immunol (2011) 186 (1): 255–263.
Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens
Anik L. Côté; Peisheng Zhang; Jeremy A. O'Sullivan; Valerie L. Jacobs; Carli R. Clemis; Shimon Sakaguchi; José A. Guevara-Patiño; Mary Jo Turk
J Immunol (2011) 186 (1): 275–283.
The TLR7 Agonist R848 Alleviates Allergic Inflammation by Targeting Invariant NKT Cells To Produce IFN-γ
Françoise Grela; Aude Aumeunier; Emilie Bardel; Linh Pham Van; Elvire Bourgeois; Jeroen Vanoirbeek; Maria Leite-de-Moraes; Elke Schneider; Michel Dy; André Herbelin; Nathalie Thieblemont
J Immunol (2011) 186 (1): 284–290.
Enhancement of Suboptimal CD8 Cytotoxic T Cell Effector Function In Vivo Using Antigen-Specific CD80 Defective T Cells
J Immunol (2011) 186 (1): 291–304.
Endogenous Cortisol and TGF-β in Human Aqueous Humor Contribute to Ocular Immune Privilege by Regulating Dendritic Cell Function
Alastair K. Denniston; Sherine H. Kottoor; Imran Khan; Kadambari Oswal; Geraint P. Williams; Joseph Abbott; Graham R. Wallace; Mike Salmon; Saaeha Rauz; Philip I. Murray; S. John Curnow
J Immunol (2011) 186 (1): 305–311.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
IMMUNOGENETICS
Persistent Survival of Prevalent Clonotypes within an Immunodominant HIV Gag-Specific CD8+ T Cell Response
David J. van Bockel; David A. Price; Mee Ling Munier; Vanessa Venturi; Tedi E. Asher; Kristin Ladell; Hui Yee Greenaway; John Zaunders; Daniel C. Douek; David A. Cooper; Miles P. Davenport; Anthony D. Kelleher
J Immunol (2011) 186 (1): 359–371.
HOST DEFENSE
Leishmania Inhibitor of Serine Peptidase 2 Prevents TLR4 Activation by Neutrophil Elastase Promoting Parasite Survival in Murine Macrophages
Marilia S. Faria; Flavia C. G. Reis; Ricardo L. Azevedo-Pereira; Lesley S. Morrison; Jeremy C. Mottram; Ana Paula C. A. Lima
J Immunol (2011) 186 (1): 411–422.
Protective Roles of CX3CR1-Mediated Signals in Toxin A-Induced Enteritis through the Induction of Heme Oxygenase-1 Expression
J Immunol (2011) 186 (1): 423–431.
Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils
Naomi N. McGovern; Andrew S. Cowburn; Linsey Porter; Sarah R. Walmsley; Charlotte Summers; Alfred A. R. Thompson; Sadia Anwar; Lisa C. Willcocks; Moira K. B. Whyte; Alison M. Condliffe; Edwin R. Chilvers
J Immunol (2011) 186 (1): 453–463.
HIV Immune Escape at an Immunodominant Epitope in HLA-B*27–Positive Individuals Predicts Viral Load Outcome
Palanee Ammaranond; David J. van Bockel; Kathy Petoumenos; Marylin McMurchie; Robert Finlayson; Melanie G. Middleton; Miles P. Davenport; Vanessa Venturi; Kazuo Suzuki; Linda Gelgor; John M. Kaldor; David A. Cooper; Anthony D. Kelleher
J Immunol (2011) 186 (1): 479–488.
Akt Contributes to Activation of the TRIF-Dependent Signaling Pathways of TLRs by Interacting with TANK-Binding Kinase 1
J Immunol (2011) 186 (1): 499–507.
INFLAMMATION
CCR2-Antagonist Prophylaxis Reduces Pulmonary Immune Pathology and Markedly Improves Survival during Influenza Infection
J Immunol (2011) 186 (1): 508–515.
A Small-Molecule Macrophage Migration Inhibitory Factor Antagonist Protects against Glomerulonephritis in Lupus-Prone NZB/NZW F1 and MRL/lpr Mice
Lin Leng; Liang Chen; Juan Fan; Dorothee Greven; Alvaro Arjona; Xin Du; David Austin; Michael Kashgarian; Zhinan Yin; Xiao R. Huang; Hui Y. Lan; Elias Lolis; David Nikolic-Paterson; Richard Bucala
J Immunol (2011) 186 (1): 527–538.
Negative Feedback Regulation of NF-κB Action by CITED2 in the Nucleus
J Immunol (2011) 186 (1): 539–548.
TLR4 through IFN-β Promotes Low Molecular Mass Hyaluronan-Induced Neutrophil Apoptosis
Shaw-Wei Leu; Liyun Shi; Changqing Xu; Yili Zhao; Baoling Liu; Yongqing Li; Aviva Shiedlin; Charlie Xiang; Huahao Shen; Deborah A. Quinn; Charles A. Hales; Hang Zhao
J Immunol (2011) 186 (1): 556–562.
EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity
Theodore J. Yun; Erin K. Harning; Keith Giza; Dania Rabah; Ping Li; Joseph W. Arndt; David Luchetti; Marco A. Biamonte; Jiandong Shi; Karen Lundgren; Anthony Manning; Marilyn R. Kehry
J Immunol (2011) 186 (1): 563–575.
5A, an Apolipoprotein A-I Mimetic Peptide, Attenuates the Induction of House Dust Mite-Induced Asthma
Xianglan Yao; Cuilian Dai; Karin Fredriksson; Pradeep K. Dagur; J. Philip McCoy; Xuan Qu; Zu-Xi Yu; Karen J. Keeran; Gayle J. Zywicke; Marcelo J. A. Amar; Alan T. Remaley; Stewart J. Levine
J Immunol (2011) 186 (1): 576–583.
Antiplatelet Activity of Valproic Acid Contributes to Decreased Soluble CD40 Ligand Production in HIV Type 1-Infected Individuals
Donna C. Davidson; Michael P. Hirschman; Sherry L. Spinelli; Craig N. Morrell; Giovanni Schifitto; Richard P. Phipps; Sanjay B. Maggirwar
J Immunol (2011) 186 (1): 584–591.
CLINICAL IMMUNOLOGY
Acquisition of Humoral Transplantation Tolerance upon De Novo Emergence of B Lymphocytes
Ronald F. Parsons; Kumar Vivek; Susan Y. Rostami; Ghazal Zekavat; Seyed M. Ziaie; Yanping Luo; Brigitte Koeberlein; Robert R. Redfield; Michael P. Cancro; Ali Naji; Hooman Noorchashm
J Immunol (2011) 186 (1): 614–620.
Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor γ or Retinoid X Receptor α Deficiency
Tamás Rőszer; María P. Menéndez-Gutiérrez; Martina I. Lefterova; Daniel Alameda; Vanessa Núñez; Mitchell A. Lazar; Thierry Fischer; Mercedes Ricote
J Immunol (2011) 186 (1): 621–631.
CORRECTIONS
Correction: Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development
Tomohito Takimoto; Yu Wakabayashi; Takashi Sekiya; Naoko Inoue; Rimpei Morita; Kenji Ichiyama; Reiko Takahashi; Mayako Asakawa; Go Muto; Tomoaki Mori; Eiichi Hasegawa; Saika Shizuya; Toshiro Hara; Masatoshi Nomura; Akihiko Yoshimura
J Immunol (2011) 186 (1): 632.
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Cover Image
Cover Image
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On the cover: Epigenetic immune lineage analysis. DNA extracted from CD4+ T lymphocytes is subjected to bisulphite conversion and PCR amplified with primers targeting the IL-17, IFNG, FOXP3 and IL-13 loci. Methylation status, and thus lineage commitment towards Th1, Th2, Th17, and regulatory T cells, is subsequently determined using methyl-sensitive single-nucleotide primer extension. Janson, P. C. J., L. B. Linton, E. Ahlén Bergman, P. Marits, M. Eberhardson, F. Piehl, V. Malmström, and O. Winqvist. 2011. Profiling of CD4+ T cells with epigenetic immune lineage analysis. J. Immunol. 186: 92–102.
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