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Issues
15 April 2011
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
BRIEF REVIEWS
Physiologic Control of the Functional Status of Foxp3+ Regulatory T Cells
J Immunol (2011) 186 (8): 4535–4540.
CUTTING EDGE
Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces Type III Rather Than Type I IFN
Xing Zhang; Terrence W. Brann; Ming Zhou; Jun Yang; Raphael M. Oguariri; Kristy B. Lidie; Hiromi Imamichi; Da-Wei Huang; Richard A. Lempicki; Michael W. Baseler; Timothy D. Veenstra; Howard A. Young; H. Clifford Lane; Tomozumi Imamichi
J Immunol (2011) 186 (8): 4541–4545.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Requirements for Eomesodermin and Promyelocytic Leukemia Zinc Finger in the Development of Innate-Like CD8+ T Cells
Scott M. Gordon; Shannon A. Carty; Jiyeon S. Kim; Tao Zou; Jennifer Smith-Garvin; Eric S. Alonzo; Ethan Haimm; Derek B. Sant’Angelo; Gary A. Koretzky; Steven L. Reiner; Martha S. Jordan
J Immunol (2011) 186 (8): 4573–4578.
Gads Regulates the Expansion Phase of CD8+ T Cell-Mediated Immunity
J Immunol (2011) 186 (8): 4579–4589.
Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8+ T Cell Responses during the Effector Phase In Vivo
Douglas V. Dolfi; Priyanka A. Duttagupta; Alina C. Boesteanu; Yvonne M. Mueller; Caspian H. Oliai; Annie B. Borowski; Peter D. Katsikis
J Immunol (2011) 186 (8): 4599–4608.
Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin β7
Patricia Monteiro; Annie Gosselin; Vanessa Sue Wacleche; Mohamed El-Far; Elias A. Said; Hassen Kared; Nathalie Grandvaux; Mohamed-Rachid Boulassel; Jean-Pierre Routy; Petronela Ancuta
J Immunol (2011) 186 (8): 4618–4630.
Impaired Basophil Induction Leads to an Age-Dependent Innate Defect in Type 2 Immunity during Helminth Infection in Mice
Hendrik J. Nel; Emily Hams; Sean P. Saunders; Niamh E. Mangan; Philip Smith; Ann Atzberger; Richard A. Flavell; Shizuo Akira; Andrew N. McKenzie; Padraic G. Fallon
J Immunol (2011) 186 (8): 4631–4639.
NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity
Taku Kobayashi; Katsuyoshi Matsuoka; Shehzad Z. Sheikh; Houda Z. Elloumi; Nobuhiko Kamada; Tadakazu Hisamatsu; Jonathan J. Hansen; Kevin R. Doty; Scott D. Pope; Stephen T. Smale; Toshifumi Hibi; Paul B. Rothman; Masaki Kashiwada; Scott E. Plevy
J Immunol (2011) 186 (8): 4649–4655.
Liver X Receptors Inhibit Macrophage Proliferation through Downregulation of Cyclins D1 and B1 and Cyclin-Dependent Kinases 2 and 4
Mónica Pascual-García; José M. Carbó; Theresa León; Jonathan Matalonga; Ruud Out; Theo Van Berkel; Maria-Rosa Sarrias; Francisco Lozano; Antonio Celada; Annabel F. Valledor
J Immunol (2011) 186 (8): 4656–4667.
The Neonatal FcR-Mediated Presentation of Immune-Complexed Antigen Is Associated with Endosomal and Phagosomal pH and Antigen Stability in Macrophages and Dendritic Cells
Xindong Liu; Li Lu; Ziyan Yang; Senthilkumar Palaniyandi; Rongyu Zeng; Lian-Yong Gao; David M. Mosser; Derry C. Roopenian; Xiaoping Zhu
J Immunol (2011) 186 (8): 4674–4686.
The TLR7 Ligand 9-Benzyl-2-Butoxy-8-Hydroxy Adenine Inhibits IL-17 Response by Eliciting IL-10 and IL-10–Inducing Cytokines
Alessandra Vultaggio; Francesca Nencini; Sara Pratesi; Laura Maggi; Antonio Guarna; Francesco Annunziato; Sergio Romagnani; Paola Parronchi; Enrico Maggi
J Immunol (2011) 186 (8): 4707–4715.
Both miR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating STAT3 Expression
Miaomiao Zhang; Qiaofei Liu; Siping Mi; Xue Liang; Zhiqian Zhang; Xiaomin Su; Jinyi Liu; Yingying Chen; Mengmeng Wang; Yuan Zhang; Fenghua Guo; Zhujun Zhang; Rongcun Yang
J Immunol (2011) 186 (8): 4716–4724.
Filarial Infection Suppresses Malaria-Specific Multifunctional Th1 and Th17 Responses in Malaria and Filarial Coinfections
Simon Metenou; Benoit Dembele; Siaka Konate; Housseini Dolo; Yaya I. Coulibaly; Abdallah A. Diallo; Lamine Soumaoro; Michel E. Coulibaly; Siaka Y. Coulibaly; Dramane Sanogo; Salif S. Doumbia; Sekou F. Traoré; Siddhartha Mahanty; Amy Klion; Thomas B. Nutman
J Immunol (2011) 186 (8): 4725–4733.
Impairment of Regulatory Capacity of CD4+CD25+ Regulatory T Cells Mediated by Dendritic Cell Polarization and Hyperthyroidism in Graves’ Disease
Chaoming Mao; Shu Wang; Yichuan Xiao; Jingwei Xu; Qian Jiang; Min Jin; Xiaohua Jiang; Hua Guo; Guang Ning; Yanyun Zhang
J Immunol (2011) 186 (8): 4734–4743.
Endogenous MHC-Related Protein 1 Is Transiently Expressed on the Plasma Membrane in a Conformation That Activates Mucosal-Associated Invariant T Cells
Wei-Jen Chua; Sojung Kim; Nancy Myers; Shouxiong Huang; Lawrence Yu; Daved H. Fremont; Michael S. Diamond; Ted H. Hansen
J Immunol (2011) 186 (8): 4744–4750.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Suppressor of Cytokine Signaling 1 Regulates Embryonic Myelopoiesis Independently of Its Effects on T Cell Development
Lynda A. O’Sullivan; Suzita M. Noor; Monique C. Trengove; Rowena S. Lewis; Clifford Liongue; Naomi S. Sprigg; Sandra E. Nicholson; Alister C. Ward
J Immunol (2011) 186 (8): 4751–4761.
Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes
Herbert G. Kasler; Bryan D. Young; Denis Mottet; Hyung W. Lim; Amy M. Collins; Eric N. Olson; Eric Verdin
J Immunol (2011) 186 (8): 4782–4793.
Hematopoietic Lineage Cell-Specific Protein 1 Functions in Concert with the Wiskott–Aldrich Syndrome Protein To Promote Podosome Array Organization and Chemotaxis in Dendritic Cells
Deborah A. Klos Dehring; Fiona Clarke; Brendon G. Ricart; Yanping Huang; Timothy S. Gomez; Edward K. Williamson; Daniel A. Hammer; Daniel D. Billadeau; Yair Argon; Janis K. Burkhardt
J Immunol (2011) 186 (8): 4805–4818.
IMMUNOGENETICS
CD5 Promotes IL-10 Production in Chronic Lymphocytic Leukemia B Cells through STAT3 and NFAT2 Activation
Soizic Garaud; Ahsen Morva; Sébastien Lemoine; Sophie Hillion; Anne Bordron; Jacques-Olivier Pers; Christian Berthou; Rizgar A. Mageed; Yves Renaudineau; Pierre Youinou
J Immunol (2011) 186 (8): 4835–4844.
HOST DEFENSE
CCL17 Controls Mast Cells for the Defense against Filarial Larval Entry
Sabine Specht; Jutta K. Frank; Judith Alferink; Bettina Dubben; Laura E. Layland; Gaelle Denece; Odile Bain; Irmgard Förster; Carsten J. Kirschning; Coralie Martin; Achim Hoerauf
J Immunol (2011) 186 (8): 4845–4852.
Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen
Mizuho Hasegawa; Takashi Yamazaki; Nobuhiko Kamada; Kazuki Tawaratsumida; Yun-Gi Kim; Gabriel Núñez; Naohiro Inohara
J Immunol (2011) 186 (8): 4872–4880.
INFLAMMATION
Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature
Vincenzo Brancaleone; Jesmond Dalli; Stefania Bena; Roderick J. Flower; Giuseppe Cirino; Mauro Perretti
J Immunol (2011) 186 (8): 4905–4914.
Mal Mediates TLR-Induced Activation of CREB and Expression of IL-10
J Immunol (2011) 186 (8): 4925–4935.
Phospholipase C-β3 Is a Key Modulator of IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells
Valentino Bezzerri; Pio d’Adamo; Alessandro Rimessi; Carmen Lanzara; Sergio Crovella; Elena Nicolis; Anna Tamanini; Emmanouil Athanasakis; Maela Tebon; Giulia Bisoffi; Mitchell L. Drumm; Michael R. Knowles; Paolo Pinton; Paolo Gasparini; Giorgio Berton; Giulio Cabrini
J Immunol (2011) 186 (8): 4946–4958.
Periostin Regulates Goblet Cell Metaplasia in a Model of Allergic Airway Inflammation
Sarita Sehra; Weiguo Yao; Evelyn T. Nguyen; Ayele-Nati N. Ahyi; Florencia M. Barbé Tuana; Shawn K. Ahlfeld; Paige Snider; Robert S. Tepper; Irina Petrache; Simon J. Conway; Mark H. Kaplan
J Immunol (2011) 186 (8): 4959–4966.
CLINICAL IMMUNOLOGY
A Unique Hybrid Renal Mononuclear Phagocyte Activation Phenotype in Murine Systemic Lupus Erythematosus Nephritis
Ramalingam Bethunaickan; Celine C. Berthier; Meera Ramanujam; Ranjit Sahu; Weijia Zhang; Yezou Sun; Erwin P. Bottinger; Lionel Ivashkiv; Matthias Kretzler; Anne Davidson
J Immunol (2011) 186 (8): 4994–5003.
CORRECTIONS
Correction: IL-2–Controlled Expression of Multiple T Cell Trafficking Genes and Th2 Cytokines in the Regulatory T Cell-Deficient Scurfy Mice: Implication to Multiorgan Inflammation and Control of Skin and Lung Inflammation
Rahul Sharma; Poonam R. Sharma; Young-Chul Kim; Norbert Leitinger; Jae K. Lee; Shu Man Fu; Shyr-Te Ju
J Immunol (2011) 186 (8): 5012–5013.
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Cover Image
Cover Image
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On the cover: Twenty-five TLR4 TIR dimer models in which the BB loop of one TIR domain interacts with the E helix of the other. Toshchakov et al. screened a library of TLR4 TIR-derived decoy peptides to demonstrate that peptides derived from these regions inhibit TLR4 signaling by binding to the TLR4 TIR. Toshchakov, V. Y., H. Szmacinski, L. A. Couture, J. R. Lakowicz, and S. N. Vogel. 2011. Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: Identification of the TLR4 Toll/IL-1 receptor domain dimerization interface. J. Immunol. 186: 4819-4827.
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