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PRESIDENTIAL ADDRESS

Life in the MHC

Jeffrey A. Frelinger

J Immunol (2011) 187 (5): 2035–2037.

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IN THIS ISSUE

In This Issue

J Immunol (2011) 187 (5): 2039–2040.

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LETTERS TO THE EDITOR

Comment on “Endothelial ICAM-1 Protein Induction Is Regulated by Cytosolic Phospholipase A₂α via Both NF-κB and CREB Transcription Factors”

Armando Rojas

J Immunol (2011) 187 (5): 2041.

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Response to Comment on “Endothelial ICAM-1 Protein Induction Is Regulated by Cytosolic Phospholipase A₂α via Both NF-κB and CREB Transcription Factors”

Rachel Levy

J Immunol (2011) 187 (5): 2041.

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PILLARS OF IMMUNOLOGY

Which Lymphoid Cells Express MHC Class II Antigens; Are TCRs Encoded within the MHC?

Ted H. Hansen

J Immunol (2011) 187 (5): 2043–2044.

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Pillars Article: A Mouse B-Cell Alloantigen Determined By Gene(s) Linked To The Major Histocompatibility Complex. The Journal of Experimental Medicine. 1973. 138: 1289–1304

David H. Sachs; James L. Cone

J Immunol (2011) 187 (5): 2045–2060.

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BRIEF REVIEWS

CD4⁺FOXP3⁺ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

S. Alice Long; Jane H. Buckner

J Immunol (2011) 187 (5): 2061–2066.

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CUTTING EDGE

Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential

Deena L. Gibbons; Lucie Abeler-Dörner; Tim Raine; Il-Young Hwang; Anett Jandke; Melanie Wencker; Livija Deban; Christopher E. Rudd; Peter M. Irving; John H. Kehrl; Adrian C. Hayday

J Immunol (2011) 187 (5): 2067–2071.

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Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

J Immunol (2011) 187 (5): 2072–2078.

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Cutting Edge: Structural Basis for the Recognition of β-Linked Glycolipid Antigens by Invariant NKT Cells

Esther Dawen Yu; Enrico Girardi; Jing Wang; Dirk M. Zajonc

J Immunol (2011) 187 (5): 2079–2083.

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Cutting Edge: A Dual Role for Type I IFNs during Polyinosinic-Polycytidylic Acid-Induced NK Cell Activation

Hélène Beuneu; Jacques Deguine; Isabelle Bouvier; James P. Di Santo; Matthew L. Albert; Philippe Bousso

J Immunol (2011) 187 (5): 2084–2088.

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Cutting Edge: Distinct Waves of BCL6 Expression during T Follicular Helper Cell Development

Dirk Baumjohann; Takaharu Okada; K. Mark Ansel

J Immunol (2011) 187 (5): 2089–2092.

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CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Reversible Senescence in Human CD4⁺CD45RA⁺CD27⁻ Memory T Cells

Diletta Di Mitri; Rita I. Azevedo; Sian M. Henson; Valentina Libri; Natalie E. Riddell; Richard Macaulay; David Kipling; Maria V. D. Soares; Luca Battistini; Arne N. Akbar

J Immunol (2011) 187 (5): 2093–2100.

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IgG Autoantibodies against Deposited C3 Inhibit Macrophage-Mediated Apoptotic Cell Engulfment in Systemic Autoimmunity

Karla D. Kenyon; Caroline Cole; Fran Crawford; John W. Kappler; Joshua M. Thurman; Donna L. Bratton; Susan A. Boackle; Peter M. Henson

J Immunol (2011) 187 (5): 2101–2111.

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CD8⁻ Dendritic Cells and Macrophages Cross-Present Poly(D,L-lactate-co-glycolate) Acid Microsphere-Encapsulated Antigen In Vivo

Christopher Schliehe; Chiara Redaelli; Sabrina Engelhardt; Michael Fehlings; Marc Mueller; Nico van Rooijen; Marc Thiry; Kai Hildner; Horst Weller; Marcus Groettrup

J Immunol (2011) 187 (5): 2112–2121.

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Tight Regulation of Diacylglycerol-Mediated Signaling Is Critical for Proper Invariant NKT Cell Development

Shudan Shen; Jinhong Wu; Sruti Srivatsan; Balachandra K. Gorentla; Jinwook Shin; Li Xu; Xiao-Ping Zhong

J Immunol (2011) 187 (5): 2122–2129.

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IL-22–Induced Regulatory CD11b⁺ APCs Suppress Experimental Autoimmune Uveitis

Yan Ke; Deming Sun; Guomin Jiang; Henry J. Kaplan; Hui Shao

J Immunol (2011) 187 (5): 2130–2139.

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Chronic B Cell Deficiency from Birth Prevents Age-Related Alterations in the B Lineage

Zohar Keren; Dana Averbuch; Gitit Shahaf; Simona Zisman-Rozen; Karin Golan; Tomer Itkin; Tsvee Lapidot; Ramit Mehr; Doron Melamed

J Immunol (2011) 187 (5): 2140–2147.

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Immune Unresponsiveness to Secondary Heterologous Bacterial Infection after Sepsis Induction Is TRAIL Dependent

Prajwal Gurung; Deepa Rai; Stephanie A. Condotta; Jeffrey C. Babcock; Vladimir P. Badovinac; Thomas S. Griffith

J Immunol (2011) 187 (5): 2148–2154.

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Lack of Th17 Cell Generation in Patients with Severe Burn Injuries

Akihito Inatsu; Mari Kogiso; Marc G. Jeschke; Akira Asai; Makiko Kobayashi; David N. Herndon; Fujio Suzuki

J Immunol (2011) 187 (5): 2155–2161.

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Analysis of Binding of KIR3DS1*014 to HLA Suggests Distinct Evolutionary History of KIR3DS1

Geraldine M. O’Connor; Eriko Yamada; Andy Rampersaud; Rasmi Thomas; Mary Carrington; Daniel W. McVicar

J Immunol (2011) 187 (5): 2162–2171.

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The Immunodominant CD8 T Cell Response to the Human Cytomegalovirus Tegument Phosphoprotein pp65_495–503 Epitope Critically Depends on CD4 T Cell Help in Vaccinated HLA-A*0201 Transgenic Mice

Michael Reiser; Andreas Wieland; Bodo Plachter; Thomas Mertens; Jochen Greiner; Reinhold Schirmbeck

J Immunol (2011) 187 (5): 2172–2180.

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Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

Daniel R. Sharda; Shan Yu; Manujendra Ray; Mario Leonardo Squadrito; Michele De Palma; Thomas A. Wynn; Sidney M. Morris, Jr.; Pamela A. Hankey

J Immunol (2011) 187 (5): 2181–2192.

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Presentation of Type B Peptide–MHC Complexes from Hen Egg White Lysozyme by TLR Ligands and Type I IFNs Independent of H2-DM Regulation

Beverly S. I. Strong; Emil R. Unanue

J Immunol (2011) 187 (5): 2193–2201.

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Enterovirus 71 2C Protein Inhibits TNF-α–Mediated Activation of NF-κB by Suppressing IκB Kinase β Phosphorylation

Zhenhua Zheng; Hongxia Li; Zhenfeng Zhang; Jin Meng; Da Mao; Bingke Bai; Baojing Lu; Panyong Mao; Qinxue Hu; Hanzhong Wang

J Immunol (2011) 187 (5): 2202–2212.

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Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis

Gopal Murugaiyan; Vanessa Beynon; Akanksha Mittal; Nicole Joller; Howard L. Weiner

J Immunol (2011) 187 (5): 2213–2221.

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Functional Capacity of Mycobacterium tuberculosis-Specific T Cell Responses in Humans Is Associated with Mycobacterial Load

Cheryl L. Day; Deborah A. Abrahams; Lesedi Lerumo; Esme Janse van Rensburg; Lynnett Stone; Terrence O’rie; Bernadette Pienaar; Marwou de Kock; Gilla Kaplan; Hassan Mahomed; Keertan Dheda; Willem A. Hanekom

J Immunol (2011) 187 (5): 2222–2232.

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MicroRNA Regulation of Molecular Networks Mapped by Global MicroRNA, mRNA, and Protein Expression in Activated T Lymphocytes

Yevgeniy A. Grigoryev; Sunil M. Kurian; Traver Hart; Aleksey A. Nakorchevsky; Caifu Chen; Daniel Campbell; Steven R. Head; John R. Yates, III; Daniel R. Salomon

J Immunol (2011) 187 (5): 2233–2243.

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FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus

Liang Zhi; Pilhan Kim; Brian D. Thompson; Costas Pitsillides; Alexander J. Bankovich; Seok-Hyun Yun; Charles P. Lin; Jason G. Cyster; Mei X. Wu

J Immunol (2011) 187 (5): 2244–2251.

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The Novel Role of SERPINB9 in Cytotoxic Protection of Human Mesenchymal Stem Cells

Najib El Haddad; Robert Moore; Dean Heathcote; Marwan Mounayar; Jamil Azzi; Bechara Mfarrej; Ibrahim Batal; Christopher Ting; Mark Atkinson; Mohamed H. Sayegh; Philip G. Ashton-Rickardt; Reza Abdi

J Immunol (2011) 187 (5): 2252–2260.

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Fungal Chitin from Asthma-Associated Home Environments Induces Eosinophilic Lung Infiltration

Steven J. Van Dyken; Daniel Garcia; Paul Porter; Xiaozhu Huang; Patricia J. Quinlan; Paul D. Blanc; David B. Corry; Richard M. Locksley

J Immunol (2011) 187 (5): 2261–2267.

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SIRPα/CD172a Regulates Eosinophil Homeostasis

Noel Verjan Garcia; Eiji Umemoto; Yasuyuki Saito; Mikako Yamasaki; Erina Hata; Takashi Matozaki; Masaaki Murakami; Yun-Jae Jung; So-Youn Woo; Ju-Young Seoh; Myoung Ho Jang; Katsuyuki Aozasa; Masayuki Miyasaka

J Immunol (2011) 187 (5): 2268–2277.

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TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function

Mukanthu H. Nyirenda; Lara Sanvito; Peter J. Darlington; Kate O’Brien; Guang-Xian Zhang; Cris S. Constantinescu; Amit Bar-Or; Bruno Gran

J Immunol (2011) 187 (5): 2278–2290.

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Phagocytosis, a Potential Mechanism for Myeloid-Derived Suppressor Cell Regulation of CD8⁺ T Cell Function Mediated through Programmed Cell Death-1 and Programmed Cell Death-1 Ligand Interaction

Young-June Kim; Su-Jung Park; Hal E. Broxmeyer

J Immunol (2011) 187 (5): 2291–2301.

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Proteasome Immunosubunits Protect against the Development of CD8 T Cell-Mediated Autoimmune Diseases

Dietmar M. W. Zaiss; Cornelis P. J. Bekker; Andrea Gröne; Benedicte A. Lie; Alice J. A. M. Sijts

J Immunol (2011) 187 (5): 2302–2309.

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Duration of Antigen Availability Influences the Expansion and Memory Differentiation of T Cells

David A. Blair; Damian L. Turner; Tina O. Bose; Quynh-Mai Pham; Keith R. Bouchard; Kristina J. Williams; Jeremy P. McAleer; Linda S. Cauley; Anthony T. Vella; Leo Lefrançois

J Immunol (2011) 187 (5): 2310–2321.

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Notch Ligand Delta-Like 4 Blockade Alleviates Experimental Autoimmune Encephalomyelitis by Promoting Regulatory T Cell Development

Ribal Bassil; Bing Zhu; Youmna Lahoud; Leonardo V. Riella; Hideo Yagita; Wassim Elyaman; Samia J. Khoury

J Immunol (2011) 187 (5): 2322–2328.

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Physiologic Control of IDO Competence in Splenic Dendritic Cells

Babak Baban; Phillip R. Chandler; Burles A. Johnson, III; Lei Huang; Minghui Li; Marlon L. Sharpe; Loise M. Francisco; Arlene H. Sharpe; Bruce R. Blazar; David H. Munn; Andrew L. Mellor

J Immunol (2011) 187 (5): 2329–2335.

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Antiasthmatic Drugs Targeting the Cysteinyl Leukotriene Receptor 1 Alleviate Central Nervous System Inflammatory Cell Infiltration and Pathogenesis of Experimental Autoimmune Encephalomyelitis

Liefeng Wang; Changsheng Du; Jie Lv; Wei Wei; Ye Cui; Xin Xie

J Immunol (2011) 187 (5): 2336–2345.

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TLT2 Potentiates Neutrophil Antibacterial Activity and Chemotaxis in Response to G Protein-Coupled Receptor-Mediated Signaling

Matthew M. Halpert; Kimberly A. Thomas; R. Glenn King; Louis B. Justement

J Immunol (2011) 187 (5): 2346–2355.

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In Vivo Analysis of Uropod Function during Physiological T Cell Trafficking

Silvia F. Soriano; Miroslav Hons; Kathrin Schumann; Varsha Kumar; Timo J. Dennier; Ruth Lyck; Michael Sixt; Jens V. Stein

J Immunol (2011) 187 (5): 2356–2364.

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P2X₇ Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP

Ben J. Gu; Bernadette M. Saunders; Steven Petrou; James S. Wiley

J Immunol (2011) 187 (5): 2365–2375.

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Enhanced Phosphoinositide 3-Kinase δ Activity Is a Frequent Event in Systemic Lupus Erythematosus That Confers Resistance to Activation-Induced T Cell Death

Abel Suárez-Fueyo; Domingo F. Barber; Jorge Martínez-Ara; Antonio C. Zea-Mendoza; Ana C. Carrera

J Immunol (2011) 187 (5): 2376–2385.

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Estrogen Receptor α Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis

Karine Lélu; Sophie Laffont; Laurent Delpy; Pierre-Emmanuel Paulet; Therese Périnat; Stefan A. Tschanz; Lucette Pelletier; Britta Engelhardt; Jean-Charles Guéry

J Immunol (2011) 187 (5): 2386–2393.

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The Role of Intermediary Domain of MyD88 in Cell Activation and Therapeutic Inhibition of TLRs

Monika Avbelj; Simon Horvat; Roman Jerala

J Immunol (2011) 187 (5): 2394–2404.

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Tolerance Induced by Apoptotic Antigen-Coupled Leukocytes Is Induced by PD-L1⁺ and IL-10–Producing Splenic Macrophages and Maintained by T Regulatory Cells

Daniel R. Getts; Danielle M. Turley; Cassandra E. Smith; Christopher T. Harp; Derrick McCarthy; Emma M. Feeney; Meghann Teague Getts; Aaron J. Martin; Xunrong Luo; Rachael L. Terry; Nicholas J. C. King; Stephen D. Miller

J Immunol (2011) 187 (5): 2405–2417.

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Plasticity of Ly-6C^hi Myeloid Cells in T Cell Regulation

Bing Zhu; Jennifer K. Kennedy; Yue Wang; Carolina Sandoval-Garcia; Li Cao; Sheng Xiao; Chuan Wu; Wassim Elyaman; Samia J. Khoury

J Immunol (2011) 187 (5): 2418–2432.

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Ral GTPases Regulate Cell-Mediated Cytotoxicity in NK Cells

Jesús Sánchez-Ruiz; Raquel Mejías; María García-Belando; Domingo F. Barber; Ana González-García

J Immunol (2011) 187 (5): 2433–2441.

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MOLECULAR AND STRUCTURAL IMMUNOLOGY

An Insertion Mutant in DQA1*0501 Restores Susceptibility to HLA-DM: Implications for Disease Associations

Tieying Hou; Henriette Macmillan; Zhenjun Chen; Catherine L. Keech; Xi Jin; John Sidney; Michael Strohman; Taejin Yoon; Elizabeth D. Mellins

J Immunol (2011) 187 (5): 2442–2452.

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TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

Oleg Y. Borbulevych; Sujatha M. Santhanagopolan; Moushumi Hossain; Brian M. Baker

J Immunol (2011) 187 (5): 2453–2463.

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AID Binds Cooperatively with UNG and Msh2-Msh6 to Ig Switch Regions Dependent upon the AID C Terminus

Sanjay Ranjit; Lyne Khair; Erin K. Linehan; Anna J. Ucher; Mrinmay Chakrabarti; Carol E. Schrader; Janet Stavnezer

J Immunol (2011) 187 (5): 2464–2475.

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Krüppel-Associated Box-Associated Protein 1 Negatively Regulates TNF-α–Induced NF-κB Transcriptional Activity by Influencing the Interactions among STAT3, p300, and NF-κB/p65

Shinya Kamitani; Sumihito Togi; Osamu Ikeda; Misa Nakasuji; Asuka Sakauchi; Yuichi Sekine; Ryuta Muromoto; Kenji Oritani; Tadashi Matsuda

J Immunol (2011) 187 (5): 2476–2483.

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Long-Distance Regulation of Fetal V_δ Gene Segment TRDV4 by the Tcrd Enhancer

Bingtao Hao; Michael S. Krangel

J Immunol (2011) 187 (5): 2484–2491.

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The Multiple Shark Ig H Chain Genes Rearrange and Hypermutate Autonomously

Catherine Zhu; Wendy Feng; Jeremy Weedon; Pauline Hua; Dimitre Stefanov; Yuko Ohta; Martin F. Flajnik; Ellen Hsu

J Immunol (2011) 187 (5): 2492–2501.

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IMMUNOGENETICS

Translation of HLA–HIV Associations to the Cellular Level: HIV Adapts To Inflate CD8 T Cell Responses against Nef and HLA-Adapted Variant Epitopes

Coral-Ann M. Almeida; Corine Bronke; Steven G. Roberts; Elizabeth McKinnon; Niamh M. Keane; Abha Chopra; Carl Kadie; Jonathan Carlson; David W. Haas; Sharon A. Riddler; Richard Haubrich; David Heckerman; Simon Mallal; Mina John

J Immunol (2011) 187 (5): 2502–2513.

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Discovery of the DIGIRR Gene from Teleost Fish: A Novel Toll–IL-1 Receptor Family Member Serving as a Negative Regulator of IL-1 Signaling

Yi-feng Gu; Yu Fang; Yang Jin; Wei-ren Dong; Li-xin Xiang; Jian-zhong Shao

J Immunol (2011) 187 (5): 2514–2530.

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HOST DEFENSE

Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7

Fan Sun; Yi-Bing Zhang; Ting-Kai Liu; Jun Shi; Bing Wang; Jian-Fang Gui

J Immunol (2011) 187 (5): 2531–2539.

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Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1β Production in Human Macrophages

Aleksey Novikov; Marco Cardone; Robert Thompson; Kevin Shenderov; Kevin D. Kirschman; Katrin D. Mayer-Barber; Timothy G. Myers; Ronald L. Rabin; Giorgio Trinchieri; Alan Sher; Carl G. Feng

J Immunol (2011) 187 (5): 2540–2547.

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TLR6-Driven Lipid Droplets in Mycobacterium leprae-Infected Schwann Cells: Immunoinflammatory Platforms Associated with Bacterial Persistence

Katherine A. Mattos; Viviane G. C. Oliveira; Heloisa D’Avila; Luciana S. Rodrigues; Roberta O. Pinheiro; Euzenir N. Sarno; Maria Cristina V. Pessolani; Patricia T. Bozza

J Immunol (2011) 187 (5): 2548–2558.

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IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

Xin-Yi Liu; Wei Chen; Bo Wei; Yu-Fei Shan; Chen Wang

J Immunol (2011) 187 (5): 2559–2568.

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Foxp3⁺ Regulatory T Cells Impede the Priming of Protective CD8⁺ T Cells

James M. Ertelt; Jared H. Rowe; Margaret A. Mysz; Charanjeet Singh; Monika Roychowdhury; Marijo N. Aguilera; Sing Sing Way

J Immunol (2011) 187 (5): 2569–2577.

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STAT3 Negatively Regulates Type I IFN-Mediated Antiviral Response

Wei-Bei Wang; David E. Levy; Chien-Kuo Lee

J Immunol (2011) 187 (5): 2578–2585.

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Pulmonary Collectins Play Distinct Roles in Host Defense against Mycobacterium avium

Shigeru Ariki; Takashi Kojima; Shinsei Gasa; Atsushi Saito; Chiaki Nishitani; Motoko Takahashi; Takeyuki Shimizu; Yuichiro Kurimura; Norimasa Sawada; Nobuhiro Fujii; Yoshio Kuroki

J Immunol (2011) 187 (5): 2586–2594.

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MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP

Lei Jin; Krista K. Hill; Holly Filak; Jennifer Mogan; Heather Knowles; Bicheng Zhang; Anne-Laure Perraud; John C. Cambier; Laurel L. Lenz

J Immunol (2011) 187 (5): 2595–2601.

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The Requirement for Potent Adjuvants To Enhance the Immunogenicity and Protective Efficacy of Protein Vaccines Can Be Overcome by Prior Immunization with a Recombinant Adenovirus

Simone C. de Cassan; Emily K. Forbes; Alexander D. Douglas; Anita Milicic; Bijender Singh; Puneet Gupta; Virander S. Chauhan; Chetan E. Chitnis; Sarah C. Gilbert; Adrian V. S. Hill; Simon J. Draper

J Immunol (2011) 187 (5): 2602–2616.

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INFLAMMATION

The Protein Kinase IKKε Is a Potential Target for the Treatment of Inflammatory Hyperalgesia

Christine V. Möser; Katharina Kynast; Katharina Baatz; Otto Quintus Russe; Nerea Ferreirós; Heike Costiuk; Ruirui Lu; Achim Schmidtko; Irmgard Tegeder; Gerd Geisslinger; Ellen Niederberger

J Immunol (2011) 187 (5): 2617–2625.

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Extracellular Histones Are Mediators of Death through TLR2 and TLR4 in Mouse Fatal Liver Injury

Jun Xu; Xiaomei Zhang; Marc Monestier; Naomi L. Esmon; Charles T. Esmon

J Immunol (2011) 187 (5): 2626–2631.

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IL-1R–Associated Kinase-1 Mediates Protein Kinase Cδ-Induced IL-1β Production in Monocytes

Rajiv Lochan Tiwari; Vishal Singh; Ankita Singh; Manoj Kumar Barthwal

J Immunol (2011) 187 (5): 2632–2645.

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A Strain of Lactobacillus casei Inhibits the Effector Phase of Immune Inflammation

Cécile Schiffer; Ana Inés Lalanne; Lydie Cassard; David A. Mancardi; Odile Malbec; Pierre Bruhns; Fariel Dif; Marc Daëron

J Immunol (2011) 187 (5): 2646–2655.

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Myeloid-Derived Suppressor Cells Infiltrate the Heart in Acute Trypanosoma cruzi Infection

Henar Cuervo; Néstor A. Guerrero; Sofía Carbajosa; Alain Beschin; Patrick De Baetselier; Núria Gironès; Manuel Fresno

J Immunol (2011) 187 (5): 2656–2665.

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Inhibition of SOCS1^−/− Lethal Autoinflammatory Disease Correlated to Enhanced Peripheral Foxp3⁺ Regulatory T Cell Homeostasis

Erin L. Collins; Lindsey D. Jager; Rea Dabelic; Patrick Benitez; Kaitlin Holdstein; Kenneth Lau; Mohammed I. Haider; Howard M. Johnson; Joseph Larkin, III

J Immunol (2011) 187 (5): 2666–2676.

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Cytokine-Induced Alterations of α7 Nicotinic Receptor in Colonic CD4 T Cells Mediate Dichotomous Response to Nicotine in Murine Models of Th1/Th17- versus Th2-Mediated Colitis

Valentin Galitovskiy; Jing Qian; Alexander I. Chernyavsky; Steve Marchenko; Vivian Gindi; Robert A. Edwards; Sergei A. Grando

J Immunol (2011) 187 (5): 2677–2687.

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Chronic Fetal Exposure to Ureaplasma parvum Suppresses Innate Immune Responses in Sheep

Suhas G. Kallapur; Boris W. Kramer; Christine L. Knox; Clare A. Berry; Jennifer J. P. Collins; Matthew W. Kemp; Ilias Nitsos; Graeme R. Polglase; James Robinson; Noah H. Hillman; John P. Newnham; Claire Chougnet; Alan H. Jobe

J Immunol (2011) 187 (5): 2688–2695.

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Zinc Finger Protein Tristetraprolin Interacts with CCL3 mRNA and Regulates Tissue Inflammation

Ju-Gyeong Kang; Marcelo J. Amar; Alan T. Remaley; Jaeyul Kwon; Perry J. Blackshear; Ping-yuan Wang; Paul M. Hwang

J Immunol (2011) 187 (5): 2696–2701.

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Absence of β₂ Integrins Impairs Regulatory T Cells and Exacerbates CD4⁺ T Cell-Dependent Autoimmune Carditis

Stefanie Haasken; Jennifer L. Auger; Bryce A. Binstadt

J Immunol (2011) 187 (5): 2702–2710.

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Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension

Min Li; Suzette R. Riddle; Maria G. Frid; Karim C. El Kasmi; Timothy A. McKinsey; Ronald J. Sokol; Derek Strassheim; Barbara Meyrick; Michael E. Yeager; Amanda R. Flockton; B. Alexandre McKeon; Douglas D. Lemon; Todd R. Horn; Adil Anwar; Carlos Barajas; Kurt R. Stenmark

J Immunol (2011) 187 (5): 2711–2722.

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Osteopontin-Stimulated Expression of Matrix Metalloproteinase-9 Causes Cardiomyopathy in the mdx Model of Duchenne Muscular Dystrophy

Saurabh Dahiya; Srikanth Givvimani; Shephali Bhatnagar; Natia Qipshidze; Suresh C. Tyagi; Ashok Kumar

J Immunol (2011) 187 (5): 2723–2731.

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Misfolded Truncated Protein τ Induces Innate Immune Response via MAPK Pathway

Andrej Kovac; Norbert Zilka; Zuzana Kazmerova; Martin Cente; Monika Zilkova; Michal Novak

J Immunol (2011) 187 (5): 2732–2739.

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NF-κB Signaling in Fetal Lung Macrophages Disrupts Airway Morphogenesis

Timothy S. Blackwell; Ashley N. Hipps; Yasutoshi Yamamoto; Wei Han; Whitney J. Barham; Michael C. Ostrowski; Fiona E. Yull; Lawrence S. Prince

J Immunol (2011) 187 (5): 2740–2747.

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Coordinated Host Responses during Pyroptosis: Caspase-1–Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation

Tessa Bergsbaken; Susan L. Fink; Andreas B. den Hartigh; Wendy P. Loomis; Brad T. Cookson

J Immunol (2011) 187 (5): 2748–2754.

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IL-1 Blockade Attenuates Islet Amyloid Polypeptide-Induced Proinflammatory Cytokine Release and Pancreatic Islet Graft Dysfunction

Clara Westwell-Roper; Derek L. Dai; Galina Soukhatcheva; Kathryn J. Potter; Nico van Rooijen; Jan A. Ehses; C. Bruce Verchere

J Immunol (2011) 187 (5): 2755–2765.

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Functional Screening of TLRs in Human Amniotic Epithelial Cells

Claire Gillaux; Céline Méhats; Daniel Vaiman; Dominique Cabrol; Michelle Breuiller-Fouché

J Immunol (2011) 187 (5): 2766–2774.

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CLINICAL IMMUNOLOGY

Cytotoxic Dendritic Cells Generated from Cancer Patients

Daniela Lakomy; Nona Janikashvili; Jennifer Fraszczak; Malika Trad; Sylvain Audia; Maxime Samson; Marion Ciudad; Julien Vinit; Catherine Vergely; Denis Caillot; Pascal Foucher; Laurent Lagrost; Salem Chouaib; Emmanuel Katsanis; Nicolas Larmonier; Bernard Bonnotte

J Immunol (2011) 187 (5): 2775–2782.

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Identification of a Novel Proinflammatory Human Skin-Homing Vγ9Vδ2 T Cell Subset with a Potential Role in Psoriasis

Ute Laggner; Paola Di Meglio; Gayathri K. Perera; Christian Hundhausen; Katie E. Lacy; Niwa Ali; Catherine H. Smith; Adrian C. Hayday; Brian J. Nickoloff; Frank O. Nestle

J Immunol (2011) 187 (5): 2783–2793.

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A SOCS-1 Promoter Variant Is Associated with Total Serum IgE Levels

Justin Mostecki; Suzanne L. Cassel; Walter T. Klimecki; Debra A. Stern; Judit Knisz; Sachiyo Iwashita; Penelope Graves; Rachel L. Miller; Maartje van Peer; Marilyn Halonen; Fernando D. Martinez; Donata Vercelli; Paul B. Rothman

J Immunol (2011) 187 (5): 2794–2802.

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Delta-Like Ligand 4 Regulates Central Nervous System T Cell Accumulation during Experimental Autoimmune Encephalomyelitis

Nathanael D. Reynolds; Nicholas W. Lukacs; Nancy Long; William J. Karpus

J Immunol (2011) 187 (5): 2803–2813.

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IL-13 Induces Connective Tissue Growth Factor in Rat Hepatic Stellate Cells via TGF-β–Independent Smad Signaling

Yan Liu; Christoph Meyer; Alexandra Müller; Frank Herweck; Qi Li; Roman Müllenbach; Peter R. Mertens; Steven Dooley; Hong-Lei Weng

J Immunol (2011) 187 (5): 2814–2823.

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Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity

Willem J. J. Falkenburg; J. Joseph Melenhorst; Marian van de Meent; Michel G. D. Kester; Pleun Hombrink; Mirjam H. M. Heemskerk; Renate S. Hagedoorn; Emma Gostick; David A. Price; J. H. Frederik Falkenburg; A. John Barrett; Inge Jedema

J Immunol (2011) 187 (5): 2824–2833.

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CORRECTIONS

Corrections: Airway Epithelial versus Immune Cell Stat1 Function for Innate Defense against Respiratory Viral Infection

Laurie P. Shornick; Audrey G. Wells; Yong Zhang; Anand C. Patel; Guangming Huang; Kazutaka Takami; Moises Sosa; Nikhil A. Shukla; Eugene Agapov; Michael J. Holtzman

J Immunol (2011) 187 (5): 2834.

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Corrections: Viral Infection of the Placenta Leads to Fetal Inflammation and Sensitization to Bacterial Products Predisposing to Preterm Labor

Ingrid Cardenas; Robert E. Means; Paulomi Aldo; Kaori Koga; Sabine M. Lang; Carmen Booth; Alejandro Manzur; Enrique Oyarzun; Roberto Romero; Gil Mor

J Immunol (2011) 187 (5): 2835.

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Cover Image

Cover Image

On the cover: A cluster of dendritic cells with plasmacytoid morphology expressing the regulatory enzyme IDO (dark brown AEC stain, hematoxylin counterstain). The image captures cells in the perifollicular region of the spleen from a mouse treated for 24 hours with TLR9 ligands (CpG oligonucleotides) to induce IDO. Baban, B., P. R. Chandler, B. A. Johnson, III, L. Huang, M. Li, M. L. Sharpe, L. M. Francisco, A. H. Sharpe, B. R. Blazar, D. H. Munn, and A. L. Mellor. 2011. Physiologic control of IDO competence in splenic dendritic cells. J. Immunol. 187: 2329–2335.
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