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Issues
1 October 2011
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
Pillars Article: CTLA-4 Can Function as a Negative Regulator of T Cell Activation. Immunity. 1994. 1: 405–413
Theresa L. Walunas; Deborah J. Lenschow; Christina Y. Bakker; Peter S. Linsley; Gordon J. Freeman; Jonathan M. Green; Craig B. Thompson; Jeffrey A. Bluestone
J Immunol (2011) 187 (7): 3466–3474.
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Mouse CD300f (CMRF-35–Like Molecule-1) Recognizes Outer Membrane-Exposed Phosphatidylserine and Can Promote Phagocytosis
Seung-Chul Choi; Venkateswara R. Simhadri; Linjie Tian; Aleksandra Gil-Krzewska; Konrad Krzewski; Francisco Borrego; John E. Coligan
J Immunol (2011) 187 (7): 3483–3487.
Cutting Edge: Virus Selectively Primes Human Langerhans Cells for CD70 Expression Promoting CD8+ T Cell Responses
Angelic M. G. van der Aar; Rosa de Groot; Marta Sanchez-Hernandez; Esther W. M. Taanman; René A. W. van Lier; Marcel B. M. Teunissen; Esther C. de Jong; Martien L. Kapsenberg
J Immunol (2011) 187 (7): 3488–3492.
Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3
Maria Bettini; Andrea L. Szymczak-Workman; Karen Forbes; Ashley H. Castellaw; Mark Selby; Xiaoyu Pan; Charles G. Drake; Alan J. Korman; Dario A. A. Vignali
J Immunol (2011) 187 (7): 3493–3498.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Low-Dose Antigen Promotes Induction of FOXP3 in Human CD4+ T Cells
S. Alice Long; Mary Rieck; Megan Tatum; Paul L. Bollyky; Rebecca P. Wu; Isabelle Muller; Jhon-Chun Ho; Heather G. Shilling; Jane H. Buckner
J Immunol (2011) 187 (7): 3511–3520.
Foxp3+-Inducible Regulatory T Cells Suppress Endothelial Activation and Leukocyte Recruitment
Elena Maganto-García; De-xiu Bu; Margarite L. Tarrio; Pilar Alcaide; Gail Newton; Gabriel K. Griffin; Kevin J. Croce; Francis W. Luscinskas; Andrew H. Lichtman; Nir Grabie
J Immunol (2011) 187 (7): 3521–3529.
Dual TCR Expression Biases Lung Inflammation in DO11.10 Transgenic Mice and Promotes Neutrophilia via Microbiota-Induced Th17 Differentiation
Muriel M. Lemaire; Laure Dumoutier; Guy Warnier; Catherine Uyttenhove; Jacques Van Snick; Magali de Heusch; Monique Stevens; Jean-Christophe Renauld
J Immunol (2011) 187 (7): 3530–3537.
Selenite Induces Posttranscriptional Blockade of HLA-E Expression and Sensitizes Tumor Cells to CD94/NKG2A-Positive NK Cells
Monika Enqvist; Gustav Nilsonne; Oscar Hammarfjord; Robert P. A. Wallin; Niklas K. Björkström; Mikael Björnstedt; Anders Hjerpe; Hans-Gustaf Ljunggren; Katalin Dobra; Karl-Johan Malmberg; Mattias Carlsten
J Immunol (2011) 187 (7): 3546–3554.
CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation
Harry Z. Qui; Adam T. Hagymasi; Suman Bandyopadhyay; Marie-Clare St. Rose; Raghunath Ramanarasimhaiah; Antoine Ménoret; Robert S. Mittler; Scott M. Gordon; Steven L. Reiner; Anthony T. Vella; Adam J. Adler
J Immunol (2011) 187 (7): 3555–3564.
MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis
J Immunol (2011) 187 (7): 3578–3586.
IL-7 Is Required for the Development of the Intrinsic Function of Marginal Zone B Cells and the Marginal Zone Microenvironment
J Immunol (2011) 187 (7): 3587–3594.
Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation
Jodi L. Karnell; Fredrick G. Karnell, III; Geoffrey L. Stephens; Bhargavi Rajan; Chris Morehouse; Ying Li; Bonnie Swerdlow; Mildred Wilson; Raphaela Goldbach-Mansky; Christopher Groves; Anthony J. Coyle; Ronald Herbst; Rachel Ettinger
J Immunol (2011) 187 (7): 3603–3612.
TCR-Induced Activation of LFA-1 Involves Signaling through Tiam1
Mikaela Grönholm; Farhana Jahan; Silvia Marchesan; Ulla Karvonen; Maria Aatonen; Suneeta Narumanchi; Carl G. Gahmberg
J Immunol (2011) 187 (7): 3613–3619.
Macrophages at the Fetal–Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10
J Immunol (2011) 187 (7): 3671–3682.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence
Jens C. Krause; Tshidi Tsibane; Terrence M. Tumpey; Chelsey J. Huffman; Bryan S. Briney; Scott A. Smith; Christopher F. Basler; James E. Crowe, Jr.
J Immunol (2011) 187 (7): 3704–3711.
IL-2 Regulates Expression of C-MAF in Human CD4 T Cells
Aradhana Rani; Behdad Afzali; Audrey Kelly; Lemlem Tewolde-Berhan; Mark Hackett; Aditi S. Kanhere; Isabela Pedroza-Pacheco; Holly Bowen; Stipo Jurcevic; Richard G. Jenner; David J. Cousins; Jack A. Ragheb; Paul Lavender; Susan John
J Immunol (2011) 187 (7): 3721–3729.
IMMUNOGENETICS
Virus-Specific CD8+ T Cells Upregulate Programmed Death-1 Expression during Acute Friend Retrovirus Infection but Are Highly Cytotoxic and Control Virus Replication
Gennadiy Zelinskyy; Lara Myers; Kirsten K. Dietze; Kathrin Gibbert; Michael Roggendorf; Jia Liu; Mengji Lu; Anke R. Kraft; Volker Teichgräber; Kim J. Hasenkrug; Ulf Dittmer
J Immunol (2011) 187 (7): 3730–3737.
HOST DEFENSE
The Role of Mannose-Binding Lectin-Associated Serine Protease-3 in Activation of the Alternative Complement Pathway
J Immunol (2011) 187 (7): 3751–3758.
Functional CD8 T Cell Memory Responding to Persistent Latent Infection Is Maintained for Life
J Immunol (2011) 187 (7): 3759–3768.
Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B Cells in 2F5 VH × VL Knockin Mice Reveals Multiple Tolerance Controls
Laurent Verkoczy; Yao Chen; Hilary Bouton-Verville; Jinsong Zhang; Marilyn Diaz; Jennifer Hutchinson; Ying-Bin Ouyang; S. Munir Alam; T. Matt Holl; Kwan-Ki Hwang; Garnett Kelsoe; Barton F. Haynes
J Immunol (2011) 187 (7): 3785–3797.
INFLAMMATION
The Process of Macrophage Migration Promotes Matrix Metalloproteinase-Independent Invasion by Tumor Cells
Romain Guiet; Emeline Van Goethem; Céline Cougoule; Stéphanie Balor; Annie Valette; Talal Al Saati; Clifford A. Lowell; Véronique Le Cabec; Isabelle Maridonneau-Parini
J Immunol (2011) 187 (7): 3806–3814.
Experimental Arthritis Triggers Periodontal Disease in Mice: Involvement of TNF-α and the Oral Microbiota
Celso Martins Queiroz-Junior; Mila Fernandes Moreira Madeira; Fernanda Matos Coelho; Vivian Vasconcelos Costa; Rafaela Leal Costa Bessoni; Larissa Fonseca da Cunha Sousa; Gustavo Pompermaier Garlet; Danielle da Glória de Souza; Mauro Martins Teixeira; Tarcília Aparecida da Silva
J Immunol (2011) 187 (7): 3821–3830.
Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2
Lily D. Lu; Kristine L. Stump; Nate H. Wallace; Pawel Dobrzanski; Cynthia Serdikoff; Diane E. Gingrich; Benjamin J. Dugan; Thelma S. Angeles; Mark S. Albom; Jennifer L. Mason; Mark A. Ator; Bruce D. Dorsey; Bruce A. Ruggeri; Matthew M. Seavey
J Immunol (2011) 187 (7): 3840–3853.
Myeloid-Specific Expression of Human Lysosomal Acid Lipase Corrects Malformation and Malfunction of Myeloid-Derived Suppressor Cells in lal−/− Mice
J Immunol (2011) 187 (7): 3854–3866.
Glycogen Synthase Kinase-3 Facilitates Con A-Induced IFN-γ–Mediated Immune Hepatic Injury
Cheng-Chieh Tsai; Wei-Ching Huang; Chia-Ling Chen; Chia-Yuan Hsieh; Yee-Shin Lin; Shun-Hua Chen; Kao-Chi Yang; Chiou-Feng Lin
J Immunol (2011) 187 (7): 3867–3877.
The P2X7 Receptor and Pannexin-1 Are Both Required for the Promotion of Multinucleated Macrophages by the Inflammatory Cytokine GM-CSF
J Immunol (2011) 187 (7): 3878–3887.
CLINICAL IMMUNOLOGY
An Acquired Defect in IgG-Dependent Phagocytosis Explains the Impairment in Antibody-Mediated Cellular Depletion in Lupus
J Immunol (2011) 187 (7): 3888–3894.
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Cover Image
Cover Image
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On the cover: Intermolecular ionic interactions between lipid A and human TLR4 are key interactions in the human TLR4/MD-2/LPS cocrystal structure. Color scheme: TLR4 is white and light purple (surface view), MD-2 is yellow and brown (surface view), and the lipid A portion of LPS is green and red (stick view). The graphics were created in PyMol. Meng, J., M. Gong, H. Björkbacka, and D. T. Golenbock. 2011. Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions. J. Immunol. 187: 3683–3693. - PDF Icon PDF LinkFront Matter
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