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15 June 2012
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
LETTERS TO THE EDITOR
Comment on “CD4+CD8+ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection”
J Immunol (2012) 188 (12): 5809.
Response to Comment on “CD4+CD8+ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection”
J Immunol (2012) 188 (12): 5809–5810.
BRIEF REVIEWS
Hidden Memories: Frontline Memory T Cells and Early Pathogen Interception
J Immunol (2012) 188 (12): 5811–5817.
CUTTING EDGE
Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism
William F. Hawse; Matthew M. Champion; Michelle V. Joyce; Lance M. Hellman; Moushumi Hossain; Veronica Ryan; Brian G. Pierce; Zhiping Weng; Brian M. Baker
J Immunol (2012) 188 (12): 5819–5823.
Cutting Edge: Slamf8 Is a Negative Regulator of Nox2 Activity in Macrophages
Guoxing Wang; Ana C. Abadía-Molina; Scott B. Berger; Xavier Romero; Michael S. O’Keeffe; Domingo I. Rojas-Barros; Marta Aleman; Gongxian Liao; Elena Maganto-García; Manuel Fresno; Ninghai Wang; Cynthia Detre; Cox Terhorst
J Immunol (2012) 188 (12): 5829–5832.
Cutting Edge: Divergent Cell-Specific Functions of MyD88 for Inflammatory Responses and Organ Injury in Septic Peritonitis
Petra Gais; Daniel Reim; Gabriela Jusek; Tanja Rossmann-Bloeck; Heike Weighardt; Klaus Pfeffer; Felicitas Altmayr; Klaus-Peter Janssen; Bernhard Holzmann
J Immunol (2012) 188 (12): 5833–5837.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
An In Vivo IL-7 Requirement for Peripheral Foxp3+ Regulatory T Cell Homeostasis
Grace Y. Kim; Davinna L. Ligons; Changwan Hong; Megan A. Luckey; Hilary R. Keller; Xuguang Tai; Philip J. Lucas; Ronald E. Gress; Jung-Hyun Park
J Immunol (2012) 188 (12): 5859–5866.
Decoy Receptor 3 Suppresses TLR2-Mediated B Cell Activation by Targeting NF-κB
Zi-Ming Huang; Jhi-Kai Kang; Chih-Yu Chen; Tz-Hau Tseng; Chien-Wen Chang; Yung-Chi Chang; Shyh-Kuan Tai; Shie-Liang Hsieh; Chuen-Miin Leu
J Immunol (2012) 188 (12): 5867–5876.
Protein Kinase C-θ Promotes Th17 Differentiation via Upregulation of Stat3
J Immunol (2012) 188 (12): 5887–5897.
CIKS/Act1-Mediated Signaling by IL-17 Cytokines in Context: Implications for How a CIKS Gene Variant May Predispose to Psoriasis
J Immunol (2012) 188 (12): 5906–5914.
Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals
Shao Chong Zhang; Eric Martin; Mariko Shimada; Sasha Blue Godfrey; Jennifer Fricke; Shirley Locastro; Nicole Y. Lai; Paul Liebesny; Jonathan M. Carlson; Chanson J. Brumme; Oluwatobi Awele Ogbechie; Huabiao Chen; Bruce D. Walker; Zabrina L. Brumme; Daniel G. Kavanagh; Sylvie Le Gall
J Immunol (2012) 188 (12): 5924–5934.
CD23+CD21highCD1dhigh B Cells in Inflamed Lymph Nodes Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential
Safiehkhatoon Moshkani; Igor I. Kuzin; Funmilola Adewale; Johan Jansson; Iñaki Sanz; Edward M. Schwarz; Andrea Bottaro
J Immunol (2012) 188 (12): 5944–5953.
Activated T Cell Exosomes Promote Tumor Invasion via Fas Signaling Pathway
Zhijian Cai; Fei Yang; Lei Yu; Zhou Yu; Lingling Jiang; Qingqing Wang; Yunshan Yang; Lie Wang; Xuetao Cao; Jianli Wang
J Immunol (2012) 188 (12): 5954–5961.
Immunological Disruption of Antiangiogenic Signals by Recruited Allospecific T Cells Leads to Corneal Allograft Rejection
Yaohong Tan; Fernando Cruz-Guilloty; Carlos A. Medina-Mendez; Nicholas J. Cutrufello; Rosa E. Martinez; Maitee Urbieta; David Wilson; Yiwen Li; Victor L. Perez
J Immunol (2012) 188 (12): 5962–5969.
Megakaryocyte Progenitors Are the Main APCs Inducing Th17 Response to Lupus Autoantigens and Foreign Antigens
J Immunol (2012) 188 (12): 5970–5980.
Lipopolysaccharide-Activated Dendritic Cells: “Exhausted” or Alert and Waiting?
J Immunol (2012) 188 (12): 5981–5989.
High DGK-α and Disabled MAPK Pathways Cause Dysfunction of Human Tumor-Infiltrating CD8+ T Cells That Is Reversible by Pharmacologic Intervention
J Immunol (2012) 188 (12): 5990–6000.
A Switch in Pathogenic Mechanism in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis in IFN-γ–Inducible Lysosomal Thiol Reductase-Free Mice
Cheryl M. Bergman; Cecilia B. Marta; Maja Maric; Steven E. Pfeiffer; Peter Cresswell; Nancy H. Ruddle
J Immunol (2012) 188 (12): 6001–6009.
The Non-Ig Parts of the VpreB and λ5 Proteins of the Surrogate Light Chain Play Opposite Roles in the Surface Representation of the Precursor B Cell Receptor
Marko Knoll; Yuki Yanagisawa; Szandor Simmons; Niklas Engels; Jürgen Wienands; Fritz Melchers; Kazuo Ohnishi
J Immunol (2012) 188 (12): 6010–6017.
BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses
Pia Dosenovic; Martina Soldemo; Jean L. Scholz; Sijy O’Dell; Emilie K. Grasset; Nadège Pelletier; Mikael C. I. Karlsson; John R. Mascola; Richard T. Wyatt; Michael P. Cancro; Gunilla B. Karlsson Hedestam
J Immunol (2012) 188 (12): 6018–6026.
The Skin, a Novel Niche for Recirculating B Cells
Skye A. Geherin; Sarah R. Fintushel; Michael H. Lee; R. Paul Wilson; Reema T. Patel; Carsten Alt; Alan J. Young; John B. Hay; Gudrun F. Debes
J Immunol (2012) 188 (12): 6027–6035.
HIV-1 Capture and Antigen Presentation by Dendritic Cells: Enhanced Viral Capture Does Not Correlate with Better T Cell Activation
Maria T. Rodriguez-Plata; Alejandra Urrutia; Sylvain Cardinaud; Maria J. Buzón; Nuria Izquierdo-Useros; Julia G. Prado; Maria C. Puertas; Itziar Erkizia; Pierre-Grégoire Coulon; Samandhy Cedeño; Bonaventura Clotet; Arnaud Moris; Javier Martinez-Picado
J Immunol (2012) 188 (12): 6036–6045.
Human CCR4+CCR6+Th17 Cells Suppress Autologous CD8+ T Cell Responses
Fei Zhao; Bastian Hoechst; Jaba Gamrekelashvili; Lars A. Ormandy; Torsten Voigtländer; Heiner Wedemeyer; Kris Ylaya; Xin Wei Wang; Stephen M. Hewitt; Michael P. Manns; Firouzeh Korangy; Tim F. Greten
J Immunol (2012) 188 (12): 6055–6062.
Differential Effects of Denileukin Diftitox IL-2 Immunotoxin on NK and Regulatory T Cells in Nonhuman Primates
Yohei Yamada; Akihiro Aoyama; Georges Tocco; Svjetlan Boskovic; Ognjenka Nadazdin; Alessandro Alessandrini; Joren C. Madsen; A. Benedict Cosimi; Gilles Benichou; Tatsuo Kawai
J Immunol (2012) 188 (12): 6063–6070.
Stromal Endothelial Cells Establish a Bidirectional Crosstalk with Chronic Lymphocytic Leukemia Cells through the TNF-Related Factors BAFF, APRIL, and CD40L
Montserrat Cols; Carolina M. Barra; Bing He; Irene Puga; Weifeng Xu; April Chiu; Wayne Tam; Daniel M. Knowles; Stacey R. Dillon; John P. Leonard; Richard R. Furman; Kang Chen; Andrea Cerutti
J Immunol (2012) 188 (12): 6071–6083.
IL-7 Functionally Segregates the Pro-B Cell Stage by Regulating Transcription of Recombination Mediators across Cell Cycle
Kristen Johnson; Julie Chaumeil; Mariann Micsinai; Joy M. H. Wang; Laura B. Ramsey; Gisele V. Baracho; Robert C. Rickert; Francesco Strino; Yuval Kluger; Michael A. Farrar; Jane A. Skok
J Immunol (2012) 188 (12): 6084–6092.
Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity
Matthew J. Johnson; Constantinos Petrovas; Takuya Yamamoto; Ross W. B. Lindsay; Karin Loré; Jason G. D. Gall; Emma Gostick; François Lefebvre; Mark J. Cameron; David A. Price; Elias Haddad; Rafick-Pierre Sekaly; Robert A. Seder; Richard A. Koup
J Immunol (2012) 188 (12): 6109–6118.
15 kDa Granulysin Causes Differentiation of Monocytes to Dendritic Cells but Lacks Cytotoxic Activity
Carol Clayberger; Michael W. Finn; Tianhong Wang; Reena Saini; Christine Wilson; Valarie A. Barr; Marianna Sabatino; Luciano Castiello; David Stroncek; Alan M. Krensky
J Immunol (2012) 188 (12): 6119–6126.
B Cell Receptor-ERK1/2 Signal Cancels PAX5-Dependent Repression of BLIMP1 through PAX5 Phosphorylation: A Mechanism of Antigen-Triggering Plasma Cell Differentiation
Takahiko Yasuda; Fumihiko Hayakawa; Shingo Kurahashi; Keiki Sugimoto; Yosuke Minami; Akihiro Tomita; Tomoki Naoe
J Immunol (2012) 188 (12): 6127–6134.
Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice
Meili Zhang; Wei Ju; Zhengsheng Yao; Ping Yu; Bih-Rong Wei; R. Mark Simpson; Rebecca Waitz; Marcella Fassò; James P. Allison; Thomas A. Waldmann
J Immunol (2012) 188 (12): 6156–6164.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Dimerization of NKp46 Receptor Is Essential for NKp46-Mediated Lysis: Characterization of the Dimerization Site by Epitope Mapping
Michal Jaron-Mendelson; Rami Yossef; Michael Y. Appel; Alon Zilka; Uzi Hadad; Fabian Afergan; Benyamin Rosental; Stanislav Engel; Shlomo Nedvetzki; Alex Braiman; Angel Porgador
J Immunol (2012) 188 (12): 6165–6174.
Negative Feedback Regulation of Antigen Receptors through Calmodulin Inhibition of E2A
J Immunol (2012) 188 (12): 6175–6183.
HLA-B27 Homodimers and Free H Chains Are Stronger Ligands for Leukocyte Ig-like Receptor B2 than Classical HLA Class I
Joanna Giles; Jackie Shaw; Christopher Piper; Isabel Wong-Baeza; Kirsty McHugh; Anna Ridley; Demin Li; Izabela Lenart; Antony N. Antoniou; Katilin DiGleria; Kimiko Kuroki; Katsumi Maenaka; Paul Bowness; Simon Kollnberger
J Immunol (2012) 188 (12): 6184–6193.
Signal-Transducing Adaptor Protein-2 Modulates Fas-Mediated T Cell Apoptosis by Interacting with Caspase-8
Yuichi Sekine; Chikako Yamamoto; Michinori Kakisaka; Ryuta Muromoto; Shigeyuki Kon; Dai Ashitomi; Natsuko Fujita; Akihiko Yoshimura; Kenji Oritani; Tadashi Matsuda
J Immunol (2012) 188 (12): 6194–6204.
HOST DEFENSE
Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis
J Immunol (2012) 188 (12): 6205–6215.
Differential Regulation of the Let-7 Family of MicroRNAs in CD4+ T Cells Alters IL-10 Expression
Sanjay Swaminathan; Kazuo Suzuki; Nabila Seddiki; Warren Kaplan; Mark J. Cowley; Chantelle L. Hood; Jennifer L. Clancy; Daniel D. Murray; Catalina Méndez; Linda Gelgor; Ben Anderson; Norman Roth; David A. Cooper; Anthony D. Kelleher
J Immunol (2012) 188 (12): 6238–6246.
Herpes Simplex Virus Type 2 Infection of Human Epithelial Cells Induces CXCL9 Expression and CD4+ T Cell Migration via Activation of p38-CCAAT/Enhancer-Binding Protein-β Pathway
Wenjie Huang; Kai Hu; Sukun Luo; Mudan Zhang; Chang Li; Wei Jin; Yalan Liu; George E. Griffin; Robin J. Shattock; Qinxue Hu
J Immunol (2012) 188 (12): 6247–6257.
Loss of TNF Signaling Facilitates the Development of a Novel Ly-6Clow Macrophage Population Permissive for Leishmania major Infection
J Immunol (2012) 188 (12): 6258–6266.
INFLAMMATION
The Transcription Factor Zeb2 Regulates Signaling in Mast Cells
Emilia Alina Barbu; Juan Zhang; Elsa H. Berenstein; Jacqueline R. Groves; Lauren M. Parks; Reuben P. Siraganian
J Immunol (2012) 188 (12): 6278–6286.
IL-17 and TNF-α Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation
Gabriel K. Griffin; Gail Newton; Margarite L. Tarrio; De-xiu Bu; Elena Maganto-Garcia; Veronica Azcutia; Pilar Alcaide; Nir Grabie; Francis W. Luscinskas; Kevin J. Croce; Andrew H. Lichtman
J Immunol (2012) 188 (12): 6287–6299.
Leukemia Inhibitory Factor Signaling Is Required for Lung Protection during Pneumonia
Lee J. Quinton; Joseph P. Mizgerd; Kristie L. Hilliard; Matthew R. Jones; Candice Y. Kwon; Eri Allen
J Immunol (2012) 188 (12): 6300–6308.
Enhanced Anti-Serpin Antibody Activity Inhibits Autoimmune Inflammation in Type 1 Diabetes
Jan Czyzyk; Octavian Henegariu; Paula Preston-Hurlburt; Raman Baldzizhar; Christine Fedorchuk; Enric Esplugues; Kim Bottomly; Frans K. Gorus; Kevan Herold; Richard A. Flavell
J Immunol (2012) 188 (12): 6319–6327.
Monocytic Thrombomodulin Triggers LPS- and Gram-Negative Bacteria-Induced Inflammatory Response
J Immunol (2012) 188 (12): 6328–6337.
RGS16 Attenuates Pulmonary Th2/Th17 Inflammatory Responses
Sucharita P. Shankar; Mark S. Wilson; Jeffrey A. DiVietro; Margaret M. Mentink-Kane; Zhihui Xie; Thomas A. Wynn; Kirk M. Druey
J Immunol (2012) 188 (12): 6347–6356.
L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes
Michael Freeley; Francis O’Dowd; Toby Paul; Dmitry Kashanin; Anthony Davies; Dermot Kelleher; Aideen Long
J Immunol (2012) 188 (12): 6357–6370.
EVI1 Acts as an Inducible Negative-Feedback Regulator of NF-κB by Inhibiting p65 Acetylation
Xiangbin Xu; Chang-Hoon Woo; Rachel R. Steere; Byung Cheol Lee; Yuxian Huang; Jing Wu; Jinjiang Pang; Jae Hyang Lim; Haidong Xu; Wenhong Zhang; Anuhya S. Konduru; Chen Yan; Michael T. Cheeseman; Steve D. M. Brown; Jian-Dong Li
J Immunol (2012) 188 (12): 6371–6380.
Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells
Andressa de Freitas; Sami Banerjee; Na Xie; Huachun Cui; Kasey I. Davis; Arnaud Friggeri; Mingui Fu; Edward Abraham; Gang Liu
J Immunol (2012) 188 (12): 6381–6388.
CLINICAL IMMUNOLOGY
Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-γ and GM-CSF
J Immunol (2012) 188 (12): 6389–6398.
CXCL17 Is a Mucosal Chemokine Elevated in Idiopathic Pulmonary Fibrosis That Exhibits Broad Antimicrobial Activity
Amanda M. Burkhardt; Kenneth P. Tai; Juan P. Flores-Guiterrez; Natalia Vilches-Cisneros; Karishma Kamdar; Oralia Barbosa-Quintana; Ricardo Valle-Rios; Peter A. Hevezi; Joaquin Zuñiga; Moises Selman; André J. Ouellette; Albert Zlotnik
J Immunol (2012) 188 (12): 6399–6406.
Adjuvant-like Effect of Vaccinia Virus 14K Protein: A Case Study with Malaria Vaccine Based on the Circumsporozoite Protein
Aneesh Vijayan; Carmen E. Gómez; Diego A. Espinosa; Alan G. Goodman; Lucas Sanchez-Sampedro; Carlos Oscar S. Sorzano; Fidel Zavala; Mariano Esteban
J Immunol (2012) 188 (12): 6407–6417.
CORRECTIONS
Correction: Protection of nonself surfaces from complement attack by factor h-binding peptides: implications for therapeutic medicine
You-Qiang Wu; Hongchang Qu; Georgia Sfyroera; Apostolia Tzekou; Brian K. Kay; Bo Nilsson; Kristina Nilsson Ekdahl; Daniel Ricklin; John D. Lambris
J Immunol (2012) 188 (12): 6425.
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Cover Image
Cover Image
On the cover: Macrophages control the capacity of mesoangioblasts to yield terminally differentiated myotubes. Myogenic differentiation was assessed, verifying by immunofluorescence the expression of MyHC (green). Macrophages were identified by the expression of CD11b (red). Nuclei were counterstained with Hoechst (blue). Bosurgi, L., G. Corna, M. Vezzoli, T. Touvier, G. Cossu, A. A. Manfredi, S. Brunelli, and P. Rovere-Querini. 2012. Transplanted mesoangioblasts require macrophage IL-10 for survival in a mouse model of muscle injury. J. Immunol. 188: 6267–6277. - PDF Icon PDF LinkFront Matter
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