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Issues
1 March 2012
ISSN 0022-1767
EISSN 1550-6606
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Fasting-Induced Hypoleptinemia Expands Functional Regulatory T Cells in Systemic Lupus Erythematosus
J Immunol (2012) 188 (5): 2070–2073.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
Multiple Receptors Trigger Human NK Cell-Mediated Cytotoxicity against Porcine Chondrocytes
J Immunol (2012) 188 (5): 2075–2083.
Adjuvant Immunotherapy of Experimental Autoimmune Encephalomyelitis: Immature Myeloid Cells Expressing CXCL10 and CXCL16 Attract CXCR3+CXCR6+ and Myelin-Specific T Cells to the Draining Lymph Nodes Rather Than the Central Nervous System
Richard A. O’Connor; Xujian Li; Seth Blumerman; Stephen M. Anderton; Randolph J. Noelle; Dyana K. Dalton
J Immunol (2012) 188 (5): 2093–2101.
HLA Anchor Optimization of the Melan-A–HLA-A2 Epitope within a Long Peptide Is Required for Efficient Cross-Priming of Human Tumor-Reactive T Cells
Joë-Marc Chauvin; Pierre Larrieu; Guillaume Sarrabayrouse; Armelle Prévost-Blondel; Renée Lengagne; Juliette Desfrançois; Nathalie Labarrière; Francine Jotereau
J Immunol (2012) 188 (5): 2102–2110.
Differential Regulation of Primary and Memory CD8 T Cell Immune Responses by Diacylglycerol Kinases
J Immunol (2012) 188 (5): 2111–2117.
MicroRNA miR-150 Is Involved in Vα14 Invariant NKT Cell Development and Function
J Immunol (2012) 188 (5): 2118–2126.
HER2/HER3 Signaling Regulates NK Cell-Mediated Cytotoxicity via MHC Class I Chain-Related Molecule A and B Expression in Human Breast Cancer Cell Lines
Riki Okita; Dimitrios Mougiakakos; Takashi Ando; Yumeng Mao; Dhifaf Sarhan; Erik Wennerberg; Barbara Seliger; Andreas Lundqvist; Kousaku Mimura; Rolf Kiessling
J Immunol (2012) 188 (5): 2136–2145.
Skin Langerin+ Dendritic Cells Transport Intradermally Injected Anti–DEC-205 Antibodies but Are Not Essential for Subsequent Cytotoxic CD8+ T Cell Responses
Vincent Flacher; Christoph H. Tripp; Bernhard Haid; Adrien Kissenpfennig; Bernard Malissen; Patrizia Stoitzner; Juliana Idoyaga; Nikolaus Romani
J Immunol (2012) 188 (5): 2146–2155.
Brain-Derived Antigens in Lymphoid Tissue of Patients with Acute Stroke
J Immunol (2012) 188 (5): 2156–2163.
Maintenance of T Cell Function in the Face of Chronic Antigen Stimulation and Repeated Reactivation for a Latent Virus Infection
Laura K. Mackay; Linda Wakim; Catherine J. van Vliet; Claerwen M. Jones; Scott N. Mueller; Oliver Bannard; Douglas T. Fearon; William R. Heath; Francis R. Carbone
J Immunol (2012) 188 (5): 2173–2178.
The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine
J Immunol (2012) 188 (5): 2189–2197.
Distinct Kinetics of Gag-Specific CD4+ and CD8+ T Cell Responses during Acute HIV-1 Infection
Catherine Riou; Vitaly V. Ganusov; Suzanne Campion; Mandla Mlotshwa; Michael K. P. Liu; Victoria E. Whale; Nilu Goonetilleke; Persephone Borrow; Guido Ferrari; Michael R. Betts; Barton F. Haynes; Andrew J. McMichael; Clive M. Gray
J Immunol (2012) 188 (5): 2198–2206.
Potently Immunosuppressive 5-Fluorouracil–Resistant Mesenchymal Stromal Cells Completely Remit an Experimental Autoimmune Disease
J Immunol (2012) 188 (5): 2207–2217.
Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets
J Immunol (2012) 188 (5): 2218–2226.
Manipulation of CD98 Resolves Type 1 Diabetes in Nonobese Diabetic Mice
Gaojian Lian; Hideki Arimochi; Akiko Kitamura; Jun Nishida; Shigen Li; Kenji Kishihara; Yoichi Maekawa; Koji Yasutomo
J Immunol (2012) 188 (5): 2227–2234.
Mutation of a Positively Charged Cytoplasmic Motif within CD1d Results in Multiple Defects in Antigen Presentation to NKT Cells
J Immunol (2012) 188 (5): 2235–2243.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Interaction of Ets-1 with HDAC1 Represses IL-10 Expression in Th1 Cells
Choong-Gu Lee; Ho-Keun Kwon; Anupama Sahoo; Won Hwang; Jae-Seon So; Ji-Sun Hwang; Chang-Suk Chae; Gi-Cheon Kim; Jung-Eun Kim; Hong-Seob So; Eun Sook Hwang; Roland Grenningloh; I-Cheng Ho; Sin-Hyeog Im
J Immunol (2012) 188 (5): 2244–2253.
Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties
Jerome Kerzerho; Esther D. Yu; Carolina M. Barra; Elisenda Alari-Pahisa; Enrico Girardi; Youssef Harrak; Pilar Lauzurica; Amadeu Llebaria; Dirk M. Zajonc; Omid Akbari; A. Raúl Castaño
J Immunol (2012) 188 (5): 2254–2265.
A Developmentally Controlled Competitive STAT5–PU.1 DNA Binding Mechanism Regulates Activity of the Ig κE3′ Enhancer
J Immunol (2012) 188 (5): 2276–2284.
IMMUNOGENETICS
Skewed Primary Igκ Repertoire and V–J Joining in C57BL/6 Mice: Implications for Recombination Accessibility and Receptor Editing
J Immunol (2012) 188 (5): 2305–2315.
HOST DEFENSE
Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps
Jing Yan; Xiaomei Meng; Lyn M. Wancket; Katherine Lintner; Leif D. Nelin; Bernadette Chen; Kevin P. Francis; Charles V. Smith; Lynette K. Rogers; Yusen Liu
J Immunol (2012) 188 (5): 2316–2327.
Reciprocal Regulation of Protein Kinase C Isoforms Results in Differential Cellular Responsiveness
J Immunol (2012) 188 (5): 2328–2337.
Exposure to Nicotine Adversely Affects the Dendritic Cell System and Compromises Host Response to Vaccination
J Immunol (2012) 188 (5): 2359–2370.
INFLAMMATION
The MC159 Protein from the Molluscum Contagiosum Poxvirus Inhibits NF-κB Activation by Interacting with the IκB Kinase Complex
J Immunol (2012) 188 (5): 2371–2379.
The IKKα-Dependent NF-κB p52/RelB Noncanonical Pathway Is Essential To Sustain a CXCL12 Autocrine Loop in Cells Migrating in Response to HMGB1
J Immunol (2012) 188 (5): 2380–2386.
CD163-L1 Is an Endocytic Macrophage Protein Strongly Regulated by Mediators in the Inflammatory Response
Jesper B. Moeller; Marianne J. Nielsen; Martin P. Reichhardt; Anders Schlosser; Grith L. Sorensen; Ole Nielsen; Ida Tornøe; Jørn Grønlund; Maria E. Nielsen; Jan S. Jørgensen; Ole N. Jensen; Jan Mollenhauer; Søren K. Moestrup; Uffe Holmskov
J Immunol (2012) 188 (5): 2399–2409.
IL-22 Mediates Host Defense against an Intestinal Intracellular Parasite in the Absence of IFN-γ at the Cost of Th17-Driven Immunopathology
Jörg Stange; Matthew R. Hepworth; Sebastian Rausch; Lara Zajic; Anja A. Kühl; Catherine Uyttenhove; Jean-Christophe Renauld; Susanne Hartmann; Richard Lucius
J Immunol (2012) 188 (5): 2410–2418.
Proteinase 3 Contributes to Transendothelial Migration of NB1-Positive Neutrophils
J Immunol (2012) 188 (5): 2419–2426.
Epithelial Cell-Intrinsic Notch Signaling Plays an Essential Role in the Maintenance of Gut Immune Homeostasis
Yuuki Obata; Daisuke Takahashi; Masashi Ebisawa; Kisa Kakiguchi; Shigenobu Yonemura; Toshi Jinnohara; Takashi Kanaya; Yumiko Fujimura; Masumi Ohmae; Koji Hase; Hiroshi Ohno
J Immunol (2012) 188 (5): 2427–2436.
MicroRNA-127 Inhibits Lung Inflammation by Targeting IgG Fcγ Receptor I
J Immunol (2012) 188 (5): 2437–2444.
CLINICAL IMMUNOLOGY
Phenotypic Analysis of Pneumococcal Polysaccharide-Specific B Cells
Noor Khaskhely; Jason Mosakowski; Rebecca S. Thompson; Sadik Khuder; S. Louise Smithson; M. A. Julie Westerink
J Immunol (2012) 188 (5): 2455–2463.
Decoy Receptor 3 Enhances Tumor Progression via Induction of Tumor-Associated Macrophages
Shyh-Kuan Tai; Hsin-Chuan Chang; Keng-Li Lan; Chun-Ting Lee; Chih-Ya Yang; Nien-Jung Chen; Teh-Ying Chou; Der-Cherng Tarng; Shie-Liang Hsieh
J Immunol (2012) 188 (5): 2464–2471.
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Cover Image
Cover Image
On the cover: Red signals represent immunofluorescence detection of an adherens junction component E-cadherin in the colonic epithelium of mice with intestinal epithelium-specific deletion of Rbpj, a transcription factor that is responsible for Notch signaling. Nuclei were counterstained with DAPI (blue). Obata, Y., D. Takahashi, M. Ebisawa, K. Kakiguchi, S. Yonemura, T. Jinnohara, T. Kanaya, Y. Fujimura, M. Ohmae, K. Hase and H. Ohno. 2012. Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis. J. Immunol. 188: 2427–2436. - PDF Icon PDF LinkFront Matter
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