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1 July 2013
ISSN 0022-1767
EISSN 1550-6606
In this Issue
EDITORIAL
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
ANTIGEN RECOGNITION AND RESPONSES
Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation
Kerrie J. Sandgren; Anna Smed-Sörensen; Mattias N. Forsell; Martina Soldemo; William C. Adams; Frank Liang; Leif Perbeck; Richard A. Koup; Richard T. Wyatt; Gunilla B. Karlsson Hedestam; Karin Loré
J Immunol (2013) 191 (1): 60–69.
AUTOIMMUNITY
The Disease-Ameliorating Function of Autoregulatory CD8 T Cells Is Mediated by Targeting of Encephalitogenic CD4 T Cells in Experimental Autoimmune Encephalomyelitis
Sterling B. Ortega; Venkatesh P. Kashi; Andrew F. Tyler; Khrishen Cunnusamy; Jason P. Mendoza; Nitin J. Karandikar
J Immunol (2013) 191 (1): 117–126.
CLINICAL AND HUMAN IMMUNOLOGY
Antibody-Secreting Cells with a Phenotype of Ki-67low, CD138high, CD31high, and CD38high Secrete Nonspecific IgM during Primary Hepatitis A Virus Infection
Seokchan Hong; Hyun Woong Lee; Dong-Yeop Chang; Sooseong You; Jihye Kim; Jun Yong Park; Sang Hoon Ahn; Dongeun Yong; Kwang-Hyub Han; Ook Joon Yoo; Eui-Cheol Shin
J Immunol (2013) 191 (1): 127–134.
Autologous Tax-Specific CTL Therapy in a Primary Adult T Cell Leukemia/Lymphoma Cell–Bearing NOD/Shi-scid, IL-2Rγnull Mouse Model
Ayako Masaki; Takashi Ishida; Susumu Suzuki; Asahi Ito; Fumiko Mori; Fumihiko Sato; Tomoko Narita; Tomiko Yamada; Masaki Ri; Shigeru Kusumoto; Hirokazu Komatsu; Yuetsu Tanaka; Akio Niimi; Hiroshi Inagaki; Shinsuke Iida; Ryuzo Ueda
J Immunol (2013) 191 (1): 135–144.
Fetal–Maternal Alignment of Regulatory T Cells Correlates with IL-10 and Bcl-2 Upregulation in Pregnancy
Brigitte Santner-Nanan; Kathrin Straubinger; Peter Hsu; Grant Parnell; Ben Tang; Bei Xu; Angela Makris; Annemarie Hennessy; Michael J. Peek; Dirk H. Busch; Clarissa Prazeres da Costa; Ralph Nanan
J Immunol (2013) 191 (1): 145–153.
IMMUNE REGULATION
Nitric Oxide–Induced Regulatory T Cells Inhibit Th17 but Not Th1 Cell Differentiation and Function
Wanda Niedbala; Anne-Gaelle Besnard; Hui R. Jiang; Jose C. Alves-Filho; Sandra Y. Fukada; Daniela Nascimento; Akio Mitani; Peter Pushparaj; Mohammed H. Alqahtani; Foo Y. Liew
J Immunol (2013) 191 (1): 164–170.
Phosphatidylinositol 3-Kinase–Independent Signaling Pathways Contribute to ICOS-Mediated T Cell Costimulation in Acute Graft-Versus-Host Disease in Mice
Jun Li; Jessica Heinrichs; Julien Leconte; Kelley Haarberg; Kenrick Semple; Chen Liu; Mathieu Gigoux; Mara Kornete; Ciriaco A. Piccirillo; Woong-Kyung Suh; Xue-Zhong Yu
J Immunol (2013) 191 (1): 200–207.
IMMUNOTHERAPY AND VACCINES
INFECTIOUS DISEASE AND HOST RESPONSE
Enhanced T Cell Function in a Mouse Model of Human Glycosylation
George Buchlis; Pamela Odorizzi; Paula C. Soto; Oliver M. T. Pearce; Daniel J. Hui; Martha S. Jordan; Ajit Varki; E. John Wherry; Katherine A. High
J Immunol (2013) 191 (1): 228–237.
Cryptococcus gattii Is Killed by Dendritic Cells, but Evades Adaptive Immunity by Failing To Induce Dendritic Cell Maturation
Shaunna M. Huston; Shu Shun Li; Danuta Stack; Martina Timm-McCann; Gareth J. Jones; Anowara Islam; Byron M. Berenger; Richard F. Xiang; Pina Colarusso; Christopher H. Mody
J Immunol (2013) 191 (1): 249–261.
Leishmania-Infected MHC Class IIhigh Dendritic Cells Polarize CD4+ T Cells toward a Nonprotective T-bet+ IFN-γ+ IL-10+ Phenotype
Mariana Resende; Diana Moreira; Jorge Augusto; Joana Cunha; Bruno Neves; Maria Teresa Cruz; Jérôme Estaquier; Anabela Cordeiro-da-Silva; Ricardo Silvestre
J Immunol (2013) 191 (1): 262–273.
Dormant Mycobacterium tuberculosis Fails To Block Phagosome Maturation and Shows Unexpected Capacity To Stimulate Specific Human T Lymphocytes
Sabrina Mariotti; Manuela Pardini; Maria Cristina Gagliardi; Raffaela Teloni; Federico Giannoni; Maurizio Fraziano; Francesco Lozupone; Stefania Meschini; Roberto Nisini
J Immunol (2013) 191 (1): 274–282.
MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B
Saifeng Wang; Xiaojun Zhang; Ying Ju; Bao Zhao; Xiaoli Yan; Jun Hu; Lei Shi; Lebing Yang; Zhibo Ma; Lizhao Chen; Yali Liu; Zhongping Duan; Xinyue Chen; Songdong Meng
J Immunol (2013) 191 (1): 293–301.
Influenza A Virus Infection Impairs Mycobacteria-Specific T Cell Responses and Mycobacterial Clearance in the Lung during Pulmonary Coinfection
Manuela Flórido; Michael A. Grima; Caitlin M. Gillis; Yingju Xia; Stephen J. Turner; James A. Triccas; John Stambas; Warwick J. Britton
J Immunol (2013) 191 (1): 302–311.
INNATE IMMUNITY AND INFLAMMATION
The Bacterial Quorum-Sensing Signal Molecule N-3-Oxo-Dodecanoyl-l-Homoserine Lactone Reciprocally Modulates Pro- and Anti-Inflammatory Cytokines in Activated Macrophages
Yifat Glucksam-Galnoy; Roy Sananes; Nava Silberstein; Pnina Krief; Vladimir V. Kravchenko; Michael M. Meijler; Tsaffrir Zor
J Immunol (2013) 191 (1): 337–344.
Staphylococcus aureus Formyl Peptide Receptor–like 1 Inhibitor (FLIPr) and Its Homologue FLIPr-like Are Potent FcγR Antagonists That Inhibit IgG-Mediated Effector Functions
Annette M. Stemerding; Jörg Köhl; Manoj K. Pandey; Annemarie Kuipers; Jeanette H. Leusen; Peter Boross; Maaike Nederend; Gestur Vidarsson; Annemarie Y. L. Weersink; Jan G. J. van de Winkel; Kok P. M. van Kessel; Jos A. G. van Strijp
J Immunol (2013) 191 (1): 353–362.
CD166/ALCAM Mediates Proinflammatory Effects of S100B in Delayed Type Hypersensitivity
Rüdiger von Bauer; Dimitrios Oikonomou; Alba Sulaj; Sawsan Mohammed; Agnes Hotz-Wagenblatt; Hermann-Josef Gröne; Bernd Arnold; Christine Falk; Dorit Luethje; Axel Erhardt; David M. Stern; Angelika Bierhaus; Peter P. Nawroth
J Immunol (2013) 191 (1): 369–377.
Cyclooxygenase-2 Deficiency in Macrophages Leads to Defective p110γ PI3K Signaling and Impairs Cell Adhesion and Migration
J Immunol (2013) 191 (1): 395–406.
GILZ Overexpression Inhibits Endothelial Cell Adhesive Function through Regulation of NF-κB and MAPK Activity
Qiang Cheng; Huapeng Fan; Devi Ngo; Elaine Beaulieu; Patrick Leung; Camden Y. Lo; Rosemary Burgess; Yvonne G. van der Zwan; Stefan J. White; Levon M. Khachigian; Michael J. Hickey; Eric F. Morand
J Immunol (2013) 191 (1): 424–433.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
TRANSPLANTATION
Unconventional RORγt+ T Cells Drive Hepatic Ischemia Reperfusion Injury
Elke Eggenhofer; Jordi Rovira; Manije Sabet-Baktach; Anja Groell; Marcus N. Scherer; Marc-Hendrik Dahlke; Stefan A. Farkas; Martin Loss; Gudrun E. Koehl; Sven A. Lang; Michael Melter; Hans J. Schlitt; Edward K. Geissler; Alexander Kroemer
J Immunol (2013) 191 (1): 480–487.
Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells
Tao Wu; James S. Young; Heather Johnston; Xiong Ni; Ruishu Deng; Jeremy Racine; Miao Wang; Audrey Wang; Ivan Todorov; Jianmin Wang; Defu Zeng
J Immunol (2013) 191 (1): 488–499.
TUMOR IMMUNOLOGY
Critical Role of Dendritic Cell–Derived IL-27 in Antitumor Immunity through Regulating the Recruitment and Activation of NK and NKT Cells
Jun Wei; Siyuan Xia; Huayan Sun; Song Zhang; Jingya Wang; Huiyuan Zhao; Xiaoli Wu; Xi Chen; Jianlei Hao; Xinglong Zhou; Zhengmao Zhu; Xiang Gao; Jian-xin Gao; Puyue Wang; Zhenzhou Wu; Liqing Zhao; Zhinan Yin
J Immunol (2013) 191 (1): 500–508.
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Cover Image
Cover Image
![issue cover]()
On the cover: Focal adhesion formation on peritoneal macrophages treated with PGE2 for 18 h. Vinculin (red) accumulates in focal adhesion plaques, and anchors filamentous actin stress fibers (green) to the cytoplasmic membrane. M. D. Díaz-Muoz, I. C. Osma-García, M. A. Íñiguez, and M. Fresno. 2013. Cyclooxygenase-2 deficiency in macrophages leads to defective p110γ PI3K signaling and impairs cell adhesion and migration. J. Immunol. 191: 395–406.
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