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Volume 191, Issue 2
15 July 2013
Issue Cover
ISSN 0022-1767
EISSN 1550-6606

IN THIS ISSUE

In This Issue
J Immunol (2013) 191 (2): 523–524.
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LETTERS TO THE EDITOR

Comment on “CXCL9 Causes Heterologous Desensitization of CXCL12-Mediated Memory T Lymphocyte Activation”
Graeme O’Boyle; Simi Ali; John A. Kirby
J Immunol (2013) 191 (2): 525.
View articletitled, Comment on “CXCL9 Causes Heterologous Desensitization of CXCL12-Mediated Memory T Lymphocyte Activation”
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Response to Comment on “CXCL9 Causes Heterologous Desensitization of CXCL12-Mediated Memory T Lymphocyte Activation”
Oliver Giegold; Nadine Ogrissek; Heinfried H. Radeke
J Immunol (2013) 191 (2): 525–526.
View articletitled, Response to Comment on “CXCL9 Causes Heterologous Desensitization of CXCL12-Mediated Memory T Lymphocyte Activation”
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BRIEF REVIEWS

Immune Regulation in Obesity-Associated Adipose Inflammation
Jonathan M. Han; Megan K. Levings
J Immunol (2013) 191 (2): 527–532.
View articletitled, Immune Regulation in Obesity-Associated Adipose Inflammation
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CUTTING EDGE

Cutting Edge: ABIN-1 Protects against Psoriasis by Restricting MyD88 Signals in Dendritic Cells
Joseph A. Callahan; Gianna E. Hammer; Alexander Agelides; Bao H. Duong; Shigeru Oshima; Jeffrey North; Rommel Advincula; Nataliya Shifrin; Hong-An Truong; Jonathan Paw; Julio Barrera; Anthony DeFranco; Michael D. Rosenblum; Barbara A. Malynn; Averil Ma
J Immunol (2013) 191 (2): 535–539.
View articletitled, Cutting Edge: ABIN-1 Protects against Psoriasis by Restricting MyD88 Signals in Dendritic Cells
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Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells
Ben Youngblood; Alessandra Noto; Filippos Porichis; Rama S. Akondy; Zaza M. Ndhlovu; James W. Austin; Rebeka Bordi; Francesco A. Procopio; Toshiyuki Miura; Todd M. Allen; John Sidney; Alessandro Sette; Bruce D. Walker; Rafi Ahmed; Jeremy M. Boss; Rafick-Pierre Sékaly; Daniel E. Kaufmann
J Immunol (2013) 191 (2): 540–544.
View articletitled, Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells
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Cutting Edge: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses
Angela S. Archambault; Javier A. Carrero; Lisa G. Barnett; Nigel G. McGee; Julia Sim; Jonathan O. Wright; Tobias Raabe; Peiquin Chen; Hua Ding; Eric J. Allenspach; Ioannis Dragatsis; Terri M. Laufer; Gregory F. Wu
J Immunol (2013) 191 (2): 545–550.
View articletitled, Cutting Edge: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses
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ANTIGEN RECOGNITION AND RESPONSES

Phl p 1–Specific Human Monoclonal IgE and Design of a Hypoallergenic Group 1 Grass Pollen Allergen Fragment
Mattias Levin; Frida Rydnert; Eva Källström; Lor Wai Tan; Peter J. Wormald; Malin Lindstedt; Lennart Greiff; Mats Ohlin
J Immunol (2013) 191 (2): 551–560.
View articletitled, Phl p 1–Specific Human Monoclonal IgE and Design of a Hypoallergenic Group 1 Grass Pollen Allergen Fragment
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HLA Peptide Length Preferences Control CD8+ T Cell Responses
Melissa J. Rist; Alex Theodossis; Nathan P. Croft; Michelle A. Neller; Andrew Welland; Zhenjun Chen; Lucy C. Sullivan; Jacqueline M. Burrows; John J. Miles; Rebekah M. Brennan; Stephanie Gras; Rajiv Khanna; Andrew G. Brooks; James McCluskey; Anthony W. Purcell; Jamie Rossjohn; Scott R. Burrows
J Immunol (2013) 191 (2): 561–571.
View articletitled, HLA Peptide Length Preferences Control CD8<sup>+</sup> T Cell Responses
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The Mechanism of Splenic Invariant NKT Cell Activation Dictates Localization In Vivo
Irah L. King; Eyal Amiel; Mike Tighe; Katja Mohrs; Natacha Veerapen; Gurdyal Besra; Markus Mohrs; Elizabeth A. Leadbetter
J Immunol (2013) 191 (2): 572–582.
View articletitled, The Mechanism of Splenic Invariant NKT Cell Activation Dictates Localization In Vivo
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HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses
Rachid Boucherma; Hédia Kridane-Miledi; Romain Bouziat; Michael Rasmussen; Tanja Gatard; Francina Langa-Vives; Brigitte Lemercier; Annick Lim; Marion Bérard; Lbachir BenMohamed; Søren Buus; Ronald Rooke; François A. Lemonnier
J Immunol (2013) 191 (2): 583–593.
View articletitled, HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses
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AUTOIMMUNITY

Different Modulation of Ptpn22 in Effector and Regulatory T Cells Leads to Attenuation of Autoimmune Diabetes in Transgenic Nonobese Diabetic Mice
Li-Tzu Yeh; Shi-Chuen Miaw; Ming-Hong Lin; Feng-Cheng Chou; Shing-Jia Shieh; Yi-Ping Chuang; Shih-Hua Lin; Deh-Ming Chang; Huey-Kang Sytwu
J Immunol (2013) 191 (2): 594–607.
View articletitled, Different Modulation of <em>Ptpn22</em> in Effector and Regulatory T Cells Leads to Attenuation of Autoimmune Diabetes in Transgenic Nonobese Diabetic Mice
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Different Stages of Primary Sjögren’s Syndrome Involving Lymphotoxin and Type 1 IFN
Long Shen; Lakshmanan Suresh; Kishore Malyavantham; Przemek Kowal; Jingxiu Xuan; Matthew J. Lindemann; Julian L. Ambrus, Jr.
J Immunol (2013) 191 (2): 608–613.
View articletitled, Different Stages of Primary Sjögren’s Syndrome Involving Lymphotoxin and Type 1 IFN
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Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis
Naresha Saligrama; Laure K. Case; Roxana del Rio; Rajkumar Noubade; Cory Teuscher
J Immunol (2013) 191 (2): 614–622.
View articletitled, Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis
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CLINICAL AND HUMAN IMMUNOLOGY

Longitudinal and Integrative Biomodeling of Effector and Memory Immune Compartments after Inactivated Influenza Vaccination
Olivia Bonduelle; Nora Yahia; Sophie Siberil; Nora Benhabiles; Fabrice Carrat; Anne Krivine; Flore Rozenberg; Jordan Dimitrov; Srini V. Kaveri; Angélique Curjol; Malka Tindel; Martine Louet; Florent Desert; Odile Launay; Pierre Loulergue; Gwenaelle Badre; Christine Katlama; François Bricaire; Assia Samri; Dominique Rousset; Sylvie van der Werf; Stephane Jauréguiberry; Behazine Combadiere
J Immunol (2013) 191 (2): 623–631.
View articletitled, Longitudinal and Integrative Biomodeling of Effector and Memory Immune Compartments after Inactivated Influenza Vaccination
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IMMUNE REGULATION

T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells
Guilin Qiao; Yixia Zhao; Zhenping Li; Peter Q. Tang; Wallace Y. Langdon; Tianlan Yang; Jian Zhang
J Immunol (2013) 191 (2): 632–639.
View articletitled, T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells
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HuR Is Required for IL-17–Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization
Tomasz Herjan; Peng Yao; Wen Qian; Xiao Li; Caini Liu; Katarzyna Bulek; Dongxu Sun; Wen-Pin Yang; Jun Zhu; Aiqing He; Julie A. Carman; Serpil C. Erzurum; Howard D. Lipshitz; Paul L. Fox; Thomas A. Hamilton; Xiaoxia Li
J Immunol (2013) 191 (2): 640–649.
View articletitled, HuR Is Required for IL-17–Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization
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Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103+ Dendritic Cells
Gonghua Huang; Yanyan Wang; Hongbo Chi
J Immunol (2013) 191 (2): 650–659.
View articletitled, Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103<sup>+</sup> Dendritic Cells
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Human Bocavirus VP2 Upregulates IFN-β Pathway by Inhibiting Ring Finger Protein 125–Mediated Ubiquitination of Retinoic Acid–Inducible Gene-I
Huanle Luo; Zhenfeng Zhang; Zhenhua Zheng; Xianliang Ke; Xiaowei Zhang; Qian Li; Yan Liu; Bingke Bai; Panyong Mao; Qinxue Hu; Hanzhong Wang
J Immunol (2013) 191 (2): 660–669.
View articletitled, Human Bocavirus VP2 Upregulates IFN-β Pathway by Inhibiting Ring Finger Protein 125–Mediated Ubiquitination of Retinoic Acid–Inducible Gene-I
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IL-4 Upregulates Igα and Igβ Protein, Resulting in Augmented IgM Maturation and B Cell Receptor–Triggered B Cell Activation
Benchang Guo; Thomas L. Rothstein
J Immunol (2013) 191 (2): 670–677.
View articletitled, IL-4 Upregulates Igα and Igβ Protein, Resulting in Augmented IgM Maturation and B Cell Receptor–Triggered B Cell Activation
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STAT4 and T-bet Are Required for the Plasticity of IFN-γ Expression across Th2 Ontogeny and Influence Changes in Ifng Promoter DNA Methylation
Christopher L. Williams; Marcia M. Schilling; Sung Hoon Cho; Keunwook Lee; Mei Wei; Aditi; Mark Boothby
J Immunol (2013) 191 (2): 678–687.
View articletitled, STAT4 and T-bet Are Required for the Plasticity of IFN-γ Expression across Th2 Ontogeny and Influence Changes in <em>Ifng</em> Promoter DNA Methylation
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Contrasting Effects of Anti-Ly49A Due to MHC Class I cis Binding on NK Cell–Mediated Allogeneic Bone Marrow Cell Resistance
Maite Alvarez; Can M. Sungur; Erik Ames; Stephen K. Anderson; Claire Pomeroy; William J. Murphy
J Immunol (2013) 191 (2): 688–698.
View articletitled, Contrasting Effects of Anti-Ly49A Due to MHC Class I <em>cis</em> Binding on NK Cell–Mediated Allogeneic Bone Marrow Cell Resistance
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Critical Role of the Tumor Suppressor Tuberous Sclerosis Complex 1 in Dendritic Cell Activation of CD4 T Cells by Promoting MHC Class II Expression via IRF4 and CIITA
Hongjie Pan; Thomas F. O’Brien; Gabriela Wright; Jialong Yang; Jinwook Shin; Kenneth L. Wright; Xiao-Ping Zhong
J Immunol (2013) 191 (2): 699–707.
View articletitled, Critical Role of the Tumor Suppressor Tuberous Sclerosis Complex 1 in Dendritic Cell Activation of CD4 T Cells by Promoting MHC Class II Expression via IRF4 and CIITA
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RKIP Contributes to IFN-γ Synthesis by CD8+ T Cells after Serial TCR Triggering in Systemic Inflammatory Response Syndrome
Kyle T. Wright; Anthony T. Vella
J Immunol (2013) 191 (2): 708–716.
View articletitled, RKIP Contributes to IFN-γ Synthesis by CD8<sup>+</sup> T Cells after Serial TCR Triggering in Systemic Inflammatory Response Syndrome
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An Alternative Role for Foxp3 As an Effector T Cell Regulator Controlled through CD40
Gisela M. Vaitaitis; Jessica R. Carter; Dan M. Waid; Michael H. Olmstead; David H. Wagner, Jr.
J Immunol (2013) 191 (2): 717–725.
View articletitled, An Alternative Role for Foxp3 As an Effector T Cell Regulator Controlled through CD40
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IMMUNE SYSTEM DEVELOPMENT

Notch-Regulated Periphery B Cell Differentiation Involves Suppression of E Protein Function
Ping Zhang; Ying Zhao; Xiao-Hong Sun
J Immunol (2013) 191 (2): 726–736.
View articletitled, Notch-Regulated Periphery B Cell Differentiation Involves Suppression of E Protein Function
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A Transgenic TCR Directs the Development of IL-4+ and PLZF+ Innate CD4 T Cells
Lingqiao Zhu; Yu Qiao; Esther S. Choi; Joy Das; Derek B. Sant’Angelo; Cheong-Hee Chang
J Immunol (2013) 191 (2): 737–744.
View articletitled, A Transgenic TCR Directs the Development of IL-4<sup>+</sup> and PLZF<sup>+</sup> Innate CD4 T Cells
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Hoxa9 and Flt3 Signaling Synergistically Regulate an Early Checkpoint in Lymphopoiesis
Kimberly A. Gwin; Mariya B. Shapiro; Joseph J. Dolence; Zhixin L. Huang; Kay L. Medina
J Immunol (2013) 191 (2): 745–754.
View articletitled, Hoxa9 and Flt3 Signaling Synergistically Regulate an Early Checkpoint in Lymphopoiesis
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IMMUNOTHERAPY AND VACCINES

Immunotherapy of Radioresistant Mammary Tumors with Early Metastasis Using Molecular Chaperone Vaccines Combined with Ionizing Radiation
Desheng Weng; Baizheng Song; Shigeo Koido; Stuart K. Calderwood; Jianlin Gong
J Immunol (2013) 191 (2): 755–763.
View articletitled, Immunotherapy of Radioresistant Mammary Tumors with Early Metastasis Using Molecular Chaperone Vaccines Combined with Ionizing Radiation
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Orchestration of CD4 T Cell Epitope Preferences after Multipeptide Immunization
Jacqueline Tung; Andrea J. Sant
J Immunol (2013) 191 (2): 764–772.
View articletitled, Orchestration of CD4 T Cell Epitope Preferences after Multipeptide Immunization
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INFECTIOUS DISEASE AND HOST RESPONSE

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms
Joshua T. Mattila; Olabisi O. Ojo; Diane Kepka-Lenhart; Simeone Marino; Jin Hee Kim; Seok Yong Eum; Laura E. Via; Clifton E. Barry, III; Edwin Klein; Denise E. Kirschner; Sidney M. Morris, Jr.; Philana Ling Lin; JoAnne L. Flynn
J Immunol (2013) 191 (2): 773–784.
View articletitled, Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms
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Erythrocyte-Binding Antigens of Plasmodium falciparum Are Targets of Human Inhibitory Antibodies and Function To Evade Naturally Acquired Immunity
Kristina E. M. Persson; Freya J. I. Fowkes; Fiona J. McCallum; Nimmo Gicheru; Linda Reiling; Jack S. Richards; Danny W. Wilson; Sash Lopaticki; Alan F. Cowman; Kevin Marsh; James G. Beeson
J Immunol (2013) 191 (2): 785–794.
View articletitled, Erythrocyte-Binding Antigens of <em>Plasmodium falciparum</em> Are Targets of Human Inhibitory Antibodies and Function To Evade Naturally Acquired Immunity
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Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development
Jack S. Richards; Thangavelu U. Arumugam; Linda Reiling; Julie Healer; Anthony N. Hodder; Freya J. I. Fowkes; Nadia Cross; Christine Langer; Satoru Takeo; Alex D. Uboldi; Jennifer K. Thompson; Paul R. Gilson; Ross L. Coppel; Peter M. Siba; Christopher L. King; Motomi Torii; Chetan E. Chitnis; David L. Narum; Ivo Mueller; Brendan S. Crabb; Alan F. Cowman; Takafumi Tsuboi; James G. Beeson
J Immunol (2013) 191 (2): 795–809.
View articletitled, Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to <em>Plasmodium falciparum</em> Malaria for Vaccine and Biomarker Development
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B Cell–Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection
Jonathan M. Clingan; Mehrdad Matloubian
J Immunol (2013) 191 (2): 810–818.
View articletitled, B Cell–Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection
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INNATE IMMUNITY AND INFLAMMATION

Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis
Andreas Barratt-Due; Ebbe B. Thorgersen; Kjetil Egge; Søren Pischke; Andrey Sokolov; Bernt C. Hellerud; Julie K. Lindstad; Anne Pharo; Anjan K. Bongoni; Robert Rieben; Miles Nunn; Helge Scott; Tom E. Mollnes
J Immunol (2013) 191 (2): 819–827.
View articletitled, Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis
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CD160 Activation by Herpesvirus Entry Mediator Augments Inflammatory Cytokine Production and Cytolytic Function by NK Cells
John R. Šedý; Ryan L. Bjordahl; Vasileios Bekiaris; Matthew G. Macauley; Brian C. Ware; Paula S. Norris; Nell S. Lurain; Chris A. Benedict; Carl F. Ware
J Immunol (2013) 191 (2): 828–836.
View articletitled, CD160 Activation by Herpesvirus Entry Mediator Augments Inflammatory Cytokine Production and Cytolytic Function by NK Cells
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Trp53 Deficiency Protects against Acute Intestinal Inflammation
Martina E. Spehlmann; Carolin F. Manthey; Sara M. Dann; Elaine Hanson; Sukhman S. Sandhu; Linus Y. Liu; Farid K. Abdelmalak; Michaela A. Diamanti; Kristin Retzlaff; Jürgen Scheller; Stefan Rose-John; Florian R. Greten; Jean Y. J. Wang; Lars Eckmann
J Immunol (2013) 191 (2): 837–847.
View articletitled, <em>Trp53</em> Deficiency Protects against Acute Intestinal Inflammation
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Neutrophil Recruitment to the Lung in Both C5a- and CXCL1-Induced Alveolitis Is Impaired in Vitamin D–Binding Protein–Deficient Mice
Glenda Trujillo; David M. Habiel; Lingyin Ge; Mahalakshmi Ramadass; Nancy E. Cooke; Richard R. Kew
J Immunol (2013) 191 (2): 848–856.
View articletitled, Neutrophil Recruitment to the Lung in Both C5a- and CXCL1-Induced Alveolitis Is Impaired in Vitamin D–Binding Protein–Deficient Mice
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TLR4 Signaling Augments Monocyte Chemotaxis by Regulating G Protein–Coupled Receptor Kinase 2 Translocation
Zheng Liu; Yong Jiang; Yuehua Li; Juan Wang; Liyan Fan; Melanie J. Scott; Guozhi Xiao; Song Li; Timothy R. Billiar; Mark A. Wilson; Jie Fan
J Immunol (2013) 191 (2): 857–864.
View articletitled, TLR4 Signaling Augments Monocyte Chemotaxis by Regulating G Protein–Coupled Receptor Kinase 2 Translocation
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β-Defensin 2 and 3 Promote the Uptake of Self or CpG DNA, Enhance IFN-α Production by Human Plasmacytoid Dendritic Cells, and Promote Inflammation
Poonam Tewary; Gonzalo de la Rosa; Neeraj Sharma; Luis G. Rodriguez; Sergey G. Tarasov; O. M. Zack Howard; Hidekazu Shirota; Folkert Steinhagen; Dennis M. Klinman; De Yang; Joost J. Oppenheim
J Immunol (2013) 191 (2): 865–874.
View articletitled, β-Defensin 2 and 3 Promote the Uptake of Self or CpG DNA, Enhance IFN-α Production by Human Plasmacytoid Dendritic Cells, and Promote Inflammation
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SARM Is Required for Neuronal Injury and Cytokine Production in Response to Central Nervous System Viral Infection
Ying-Ju Hou; Rebecca Banerjee; Bobby Thomas; Carl Nathan; Adolfo García-Sastre; Aihao Ding; Melissa B. Uccellini
J Immunol (2013) 191 (2): 875–883.
View articletitled, SARM Is Required for Neuronal Injury and Cytokine Production in Response to Central Nervous System Viral Infection
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MOLECULAR AND STRUCTURAL IMMUNOLOGY

Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy
Jun Lin; Naiqian Cheng; James M. Hogle; Alasdair C. Steven; David M. Belnap
J Immunol (2013) 191 (2): 884–891.
View articletitled, Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy
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SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling
Shauna M. Dauphinee; Ashley Clayton; Angela Hussainkhel; Cindy Yang; Yoo-Jin Park; Megan E. Fuller; Josip Blonder; Timothy D. Veenstra; Aly Karsan
J Immunol (2013) 191 (2): 892–901.
View articletitled, SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling
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Opposing Roles of STAT4 and Dnmt3a in Th1 Gene Regulation
Duy Pham; Qing Yu; Crystal C. Walline; Rajarajeswari Muthukrishnan; Janice S. Blum; Mark H. Kaplan
J Immunol (2013) 191 (2): 902–911.
View articletitled, Opposing Roles of STAT4 and Dnmt3a in Th1 Gene Regulation
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An Engineered Construct Combining Complement Regulatory and Surface-Recognition Domains Represents a Minimal-Size Functional Factor H
Mario Hebecker; María Alba-Domínguez; Lubka T. Roumenina; Stefanie Reuter; Satu Hyvärinen; Marie-Agnès Dragon-Durey; T. Sakari Jokiranta; Pilar Sánchez-Corral; Mihály Józsi
J Immunol (2013) 191 (2): 912–921.
View articletitled, An Engineered Construct Combining Complement Regulatory and Surface-Recognition Domains Represents a Minimal-Size Functional Factor H
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MUCOSAL IMMUNOLOGY

Inhaled Birch Pollen Extract Induces Airway Hyperresponsiveness via Oxidative Stress but Independently of Pollen-Intrinsic NADPH Oxidase Activity, or the TLR4–TRIF Pathway
Karim H. Shalaby; Alexandra Allard-Coutu; Michael J. O’Sullivan; Emily Nakada; Salman T. Qureshi; Brian J. Day; James G. Martin
J Immunol (2013) 191 (2): 922–933.
View articletitled, Inhaled Birch Pollen Extract Induces Airway Hyperresponsiveness via Oxidative Stress but Independently of Pollen-Intrinsic NADPH Oxidase Activity, or the TLR4–TRIF Pathway
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Viral Infection of the Pregnant Cervix Predisposes to Ascending Bacterial Infection
Karen Racicot; Ingrid Cardenas; Vera Wünsche; Paulomi Aldo; Seth Guller; Robert E. Means; Roberto Romero; Gil Mor
J Immunol (2013) 191 (2): 934–941.
View articletitled, Viral Infection of the Pregnant Cervix Predisposes to Ascending Bacterial Infection
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Critical Role of Dendritic Cells in T Cell Retention in the Interfollicular Region of Peyer’s Patches
Takashi Obata; Naoko Shibata; Yoshiyuki Goto; Izumi Ishikawa; Shintaro Sato; Jun Kunisawa; Hiroshi Kiyono
J Immunol (2013) 191 (2): 942–948.
View articletitled, Critical Role of Dendritic Cells in T Cell Retention in the Interfollicular Region of Peyer’s Patches
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Paraoxonase-1 Suppresses Experimental Colitis via the Inhibition of IFN-γ Production from CD4 T Cells
Junji Yamashita; Chiaki Iwamura; Toshihiro Ito; Masakuni Narita; Yukio Hara; Tetsuya Sasaki; Daisuke Masuda; Munehisa Takahashi; Manami Tsuchiya; Kaori Hada; Makoto Ishikawa; Takato Matsuo; Yoichi Ohno; Hitoshi Tanaka; Hideya Maruyama; Yasumasa Ogawa; Toshinori Nakayama
J Immunol (2013) 191 (2): 949–960.
View articletitled, Paraoxonase-1 Suppresses Experimental Colitis via the Inhibition of IFN-γ Production from CD4 T Cells
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TUMOR IMMUNOLOGY

Inflammatory Cytokine–Mediated Evasion of Virus-Induced Tumors from NK Cell Control
Rabinarayan Mishra; Bojan Polic; Raymond M. Welsh; Eva Szomolanyi-Tsuda
J Immunol (2013) 191 (2): 961–970.
View articletitled, Inflammatory Cytokine–Mediated Evasion of Virus-Induced Tumors from NK Cell Control
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Tumor-Derived Vascular Pericytes Anergize Th Cells
Anamika Bose; Subhasis Barik; Saptak Banerjee; Tithi Ghosh; Atanu Mallick; Suchandra Bhattacharyya Majumdar; Kuntal Kanti Goswami; Avishek Bhuniya; Sayantan Banerjee; Rathindranath Baral; Walter J. Storkus; Partha Sarathi Dasgupta; Subrata Majumdar
J Immunol (2013) 191 (2): 971–981.
View articletitled, Tumor-Derived Vascular Pericytes Anergize Th Cells
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    On the cover: Model of neutralizing Ab C3 bound to a poliovirus 135S particle. C3 Ab (blue ribbon) binds bivalently to adjacent epitopes on the surface of poliovirus (surface rendering, darker hues indicate portions of poliovirus capsid closer to the particle center). The virus–Ab interaction likely inhibits a conformational change necessary for infection. Lin, J., N. Cheng, J. M. Hogle, A. C. Steven, and D. M. Belnap. 2013. Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy. J. Immunol. 191: 884–891.
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  • Online ISSN 1550-6606
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