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Volume 192, Issue 8
15 April 2014
The Journal of Immunology Cover Image for Volume 192, Issue 8
ISSN 0022-1767
EISSN 1550-6606
In this Issue
In This Issue
J Immunol (2014) 192 (8): 3453–3454.
View articletitled, In This Issue
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Iddm30 Controls Pancreatic Expression of Ccl11 (Eotaxin) and the Th1/Th2 Balance within the Insulitic Lesions
Gary Y. C. Chao; Robert H. Wallis; Leili Marandi; Terri Ning; Janice Sarmiento; Andrew D. Paterson; Philippe Poussier
J Immunol (2014) 192 (8): 3645–3653.
View articletitled, <em>Iddm30</em> Controls Pancreatic Expression of <em>Ccl11</em> (<em>Eotaxin</em>) and the Th1/Th2 Balance within the Insulitic Lesions
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Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2
Eisuke Inage; Kazumi Kasakura; Takuya Yashiro; Ryuyo Suzuki; Yosuke Baba; Nobuhiro Nakano; Mutsuko Hara; Atsushi Tanabe; Keisuke Oboki; Kenji Matsumoto; Hirohisa Saito; François Niyonsaba; Yoshikazu Ohtsuka; Hideoki Ogawa; Ko Okumura; Toshiaki Shimizu; Chiharu Nishiyama
J Immunol (2014) 192 (8): 3936–3946.
View articletitled, Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate <em>FCER1A</em>, and GATA2 Transactivates <em>FCER1A</em> and <em>MS4A2</em>
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CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration
Hideo Kohno; Tadao Maeda; Lindsay Perusek; Eric Pearlman; Akiko Maeda
J Immunol (2014) 192 (8): 3816–3827.
View articletitled, CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration
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Cutting Edge: A Double-Mutant Knockin of the CD28 YMNM and PYAP Motifs Reveals a Critical Role for the YMNM Motif in Regulation of T Cell Proliferation and Bcl-xL Expression
Jonathan S. Boomer; Christine M. Deppong; Dulari D. Shah; Traci L. Bricker; Jonathan M. Green
J Immunol (2014) 192 (8): 3465–3469.
View articletitled, Cutting Edge: A Double-Mutant Knockin of the CD28 YMNM and PYAP Motifs Reveals a Critical Role for the YMNM Motif in Regulation of T Cell Proliferation and Bcl-x<sub>L</sub> Expression
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Cutting Edge: Flt3 Ligand Mediates STAT3-Independent Expansion but STAT3-Dependent Activation of Myeloid-Derived Suppressor Cells
Brian R. Rosborough; Lisa R. Mathews; Benjamin M. Matta; Quan Liu; Dàlia Raïch-Regué; Angus W. Thomson; Hēth R. Turnquist
J Immunol (2014) 192 (8): 3470–3473.
View articletitled, Cutting Edge: Flt3 Ligand Mediates STAT3-Independent Expansion but STAT3-Dependent Activation of Myeloid-Derived Suppressor Cells
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Gene Expression in the Gitr Locus Is Regulated by NF-κB and Foxp3 through an Enhancer
Yukiko Tone; Yoko Kidani; Chihiro Ogawa; Kouhei Yamamoto; Masato Tsuda; Christian Peter; Herman Waldmann; Masahide Tone
J Immunol (2014) 192 (8): 3915–3924.
View articletitled, Gene Expression in the <em>Gitr</em> Locus Is Regulated by NF-κB and Foxp3 through an Enhancer
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B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation
Lisa G. Barnett; Helen M. A. Simkins; Burton E. Barnett; Lisa L. Korn; Andy L. Johnson; E. John Wherry; Gregory F. Wu; Terri M. Laufer
J Immunol (2014) 192 (8): 3607–3617.
View articletitled, B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation
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Tissue Requirements for Establishing Long-Term CD4+ T Cell–Mediated Immunity following Leishmania donovani Infection
Patrick T. Bunn; Amanda C. Stanley; Fabian de Labastida Rivera; Alexander Mulherin; Meru Sheel; Clare E. Alexander; Rebecca J. Faleiro; Fiona H. Amante; Marcela Montes De Oca; Shannon E. Best; Kylie R. James; Paul M. Kaye; Ashraful Haque; Christian R. Engwerda
J Immunol (2014) 192 (8): 3709–3718.
View articletitled, Tissue Requirements for Establishing Long-Term CD4<sup>+</sup> T Cell–Mediated Immunity following <em>Leishmania donovani</em> Infection
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Staphylococcus aureus Infection of Mice Expands a Population of Memory γδ T Cells That Are Protective against Subsequent Infection
Alison G. Murphy; Kate M. O’Keeffe; Stephen J. Lalor; Belinda M. Maher; Kingston H. G. Mills; Rachel M. McLoughlin
J Immunol (2014) 192 (8): 3697–3708.
View articletitled, <em>Staphylococcus aureus</em> Infection of Mice Expands a Population of Memory γδ T Cells That Are Protective against Subsequent Infection
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Myeloid-Derived Suppressor Cells Contribute to Staphylococcus aureus Orthopedic Biofilm Infection
Cortney E. Heim; Debbie Vidlak; Tyler D. Scherr; Jessica A. Kozel; Melissa Holzapfel; David E. Muirhead; Tammy Kielian
J Immunol (2014) 192 (8): 3778–3792.
View articletitled, Myeloid-Derived Suppressor Cells Contribute to <em>Staphylococcus aureus</em> Orthopedic Biofilm Infection
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Functional Characterization of Ocular-Derived Human Alphaherpesvirus Cross-Reactive CD4 T Cells
Werner J. D. Ouwendijk; Annemieke Geluk; Saskia L. Smits; Sarah Getu; Albert D. M. E. Osterhaus; Georges M. G. M. Verjans
J Immunol (2014) 192 (8): 3730–3739.
View articletitled, Functional Characterization of Ocular-Derived Human Alphaherpesvirus Cross-Reactive CD4 T Cells
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Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis
Erin C. Steinbach; Taku Kobayashi; Steven M. Russo; Shehzad Z. Sheikh; Gregory R. Gipson; Samantha T. Kennedy; Jennifer K. Uno; Yoshiyuki Mishima; Luke B. Borst; Bo Liu; Hans Herfarth; Jenny P. Y. Ting; R. Balfour Sartor; Scott E. Plevy
J Immunol (2014) 192 (8): 3958–3968.
View articletitled, Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis
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Dendritic Cell Motility and T Cell Activation Requires Regulation of Rho-Cofilin Signaling by the Rho-GTPase Activating Protein Myosin IXb
Yan Xu; Stefanie Pektor; Sandra Balkow; Sandra A. Hemkemeyer; Zhijun Liu; Kay Grobe; Peter J. Hanley; Limei Shen; Matthias Bros; Talkea Schmidt; Martin Bähler; Stephan Grabbe
J Immunol (2014) 192 (8): 3559–3568.
View articletitled, Dendritic Cell Motility and T Cell Activation Requires Regulation of Rho-Cofilin Signaling by the Rho-GTPase Activating Protein Myosin IXb
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Correction: H2S Increases Survival During Sepsis: Protective Effect of CHOP Inhibition
Marcella Ferlito; Qihong Wang; William B. Fulton; Paul M. Colombani; Luigi Marchionni; Karen Fox-Talbot; Nazareno Paolocci; Charles Steenbergen
J Immunol (2014) 192 (8): 3991.
View articletitled, Correction: H<sub>2</sub>S Increases Survival During Sepsis: Protective Effect of CHOP Inhibition
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Correction: Peripheral Tissue Homing Receptors Enable T Cell Entry into Lymph Nodes and Affect the Anatomical Distribution of Memory Cells
C. Colin Brinkman; Sherin J. Rouhani; Nithya Srinivasan; Victor H. Engelhard
J Immunol (2014) 192 (8): 3992–3995.
View articletitled, Correction: Peripheral Tissue Homing Receptors Enable T Cell Entry into Lymph Nodes and Affect the Anatomical Distribution of Memory Cells
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Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma
Takehiko Shibata; David M. Habiel; Ana L. Coelho; Steven L. Kunkel; Nicholas W. Lukacs; Cory M. Hogaboam
J Immunol (2014) 192 (8): 3569–3581.
View articletitled, Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma
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Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells
Hannah Rabenstein; Anne C. Behrendt; Joachim W. Ellwart; Ronald Naumann; Marion Horsch; Johannes Beckers; Reinhard Obst
J Immunol (2014) 192 (8): 3507–3517.
View articletitled, Differential Kinetics of Antigen Dependency of CD4<sup>+</sup> and CD8<sup>+</sup> T Cells
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Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans
Tina W. Wong; Alfred D. Doyle; James J. Lee; Diane F. Jelinek
J Immunol (2014) 192 (8): 3548–3558.
View articletitled, Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans
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IFN-λ Exerts Opposing Effects on T Cell Responses Depending on the Chronicity of the Virus Infection
Ichiro Misumi; Jason K. Whitmire
J Immunol (2014) 192 (8): 3596–3606.
View articletitled, IFN-λ Exerts Opposing Effects on T Cell Responses Depending on the Chronicity of the Virus Infection
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Regulation of Experimental Autoimmune Encephalomyelitis by TPL-2 Kinase
Srividya Sriskantharajah; Eva Gückel; Niki Tsakiri; Katrin Kierdorf; Christine Brender; Abduelhakem Ben-Addi; Marc Veldhoen; Philip N. Tsichlis; Brigitta Stockinger; Anne O’Garra; Marco Prinz; George Kollias; Steven C. Ley
J Immunol (2014) 192 (8): 3518–3529.
View articletitled, Regulation of Experimental Autoimmune Encephalomyelitis by TPL-2 Kinase
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Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody
Chris B. Russell; Hugh Rand; Jeannette Bigler; Keith Kerkof; Martin Timour; Edgar Bautista; James G. Krueger; David H. Salinger; Andrew A. Welcher; David A. Martin
J Immunol (2014) 192 (8): 3828–3836.
View articletitled, Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody
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IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β
Stefan Fichtner-Feigl; Rebecca Kesselring; Maria Martin; Florian Obermeier; Petra Ruemmele; Atsushi Kitani; Stefan M. Brunner; Michael Haimerl; Edward K. Geissler; Warren Strober; Hans J. Schlitt
J Immunol (2014) 192 (8): 3969–3980.
View articletitled, IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β
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BAFF and BAFF Receptor Levels Correlate with B Cell Subset Activation and Redistribution in Controlled Human Malaria Infection
Anja Scholzen; Anne C. Teirlinck; Else M. Bijker; Meta Roestenberg; Cornelus C. Hermsen; Stephen L. Hoffman; Robert W. Sauerwein
J Immunol (2014) 192 (8): 3719–3729.
View articletitled, BAFF and BAFF Receptor Levels Correlate with B Cell Subset Activation and Redistribution in Controlled Human Malaria Infection
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Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion
Andrew J. Fleetwood; Adrian Achuthan; Heidi Schultz; Anneline Nansen; Kasper Almholt; Pernille Usher; John A. Hamilton
J Immunol (2014) 192 (8): 3540–3547.
View articletitled, Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion
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IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex
Hironari Tamiya; Mika Terao; Tsuyoshi Takiuchi; Masaki Nakahara; Yoshiteru Sasaki; Ichiro Katayama; Hideki Yoshikawa; Kazuhiro Iwai
J Immunol (2014) 192 (8): 3793–3804.
View articletitled, IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex
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MAPK Phosphotase 5 Deficiency Contributes to Protection against Blood-Stage Plasmodium yoelii 17XL Infection in Mice
Qianqian Cheng; Qingfeng Zhang; Xindong Xu; Lan Yin; Lin Sun; Xin Lin; Chen Dong; Weiqing Pan
J Immunol (2014) 192 (8): 3686–3696.
View articletitled, MAPK Phosphotase 5 Deficiency Contributes to Protection against Blood-Stage <em>Plasmodium yoelii</em> 17XL Infection in Mice
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TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis
Fabrizio Fazzi; Joel Njah; Michelangelo Di Giuseppe; Daniel E. Winnica; Kristina Go; Ernest Sala; Claudette M. St Croix; Simon C. Watkins; Vladimir A. Tyurin; Donald G. Phinney; Cheryl L. Fattman; George D. Leikauf; Valerian E. Kagan; Luis A. Ortiz
J Immunol (2014) 192 (8): 3837–3846.
View articletitled, TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis
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The Drosophila Imd Signaling Pathway
Henna Myllymäki; Susanna Valanne; Mika Rämet
J Immunol (2014) 192 (8): 3455–3462.
View articletitled, The <em>Drosophila</em> Imd Signaling Pathway
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Humoral Immunity and CD4+ Th1 Cells Are Both Necessary for a Fully Protective Immune Response upon Secondary Infection with Brucella melitensis
Marie-Alice Vitry; Delphine Hanot Mambres; Carl De Trez; Shizuo Akira; Bernhard Ryffel; Jean-Jacques Letesson; Eric Muraille
J Immunol (2014) 192 (8): 3740–3752.
View articletitled, Humoral Immunity and CD4<sup>+</sup> Th1 Cells Are Both Necessary for a Fully Protective Immune Response upon Secondary Infection with <em>Brucella melitensis</em>
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CD56brightPerforinlow Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph
Paolo Carrega; Irene Bonaccorsi; Emma Di Carlo; Barbara Morandi; Petra Paul; Valeria Rizzello; Giuseppe Cipollone; Giuseppe Navarra; Maria Cristina Mingari; Lorenzo Moretta; Guido Ferlazzo
J Immunol (2014) 192 (8): 3805–3815.
View articletitled, CD56<sup>bright</sup>Perforin<sup>low</sup> Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph
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Signal-Transducing Adaptor Protein-2 Controls the IgE-Mediated, Mast Cell–Mediated Anaphylactic Responses
Yuichi Sekine; Keigo Nishida; Satoru Yamasaki; Ryuta Muromoto; Shigeyuki Kon; Jun-ichi Kashiwakura; Kodai Saitoh; Sumihito Togi; Akihiko Yoshimura; Kenji Oritani; Tadashi Matsuda
J Immunol (2014) 192 (8): 3488–3495.
View articletitled, Signal-Transducing Adaptor Protein-2 Controls the IgE-Mediated, Mast Cell–Mediated Anaphylactic Responses
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Presence of CD8+ T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-Infected Women despite a Low Prevalence of HIV RNA–Expressing Cells in the Tissue
Anna Gibbs; Taha Hirbod; Qingsheng Li; Karin Bohman; Terry B. Ball; Francis A. Plummer; Rupert Kaul; Joshua Kimani; Kristina Broliden; Annelie Tjernlund
J Immunol (2014) 192 (8): 3947–3957.
View articletitled, Presence of CD8<sup>+</sup> T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-Infected Women despite a Low Prevalence of HIV RNA–Expressing Cells in the Tissue
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CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile
Elena Sierra-Filardi; Concha Nieto; Ángeles Domínguez-Soto; Rubén Barroso; Paloma Sánchez-Mateos; Amaya Puig-Kroger; María López-Bravo; Jorge Joven; Carlos Ardavín; José L. Rodríguez-Fernández; Carmen Sánchez-Torres; Mario Mellado; Ángel L. Corbí
J Immunol (2014) 192 (8): 3858–3867.
View articletitled, CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile
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Involvement of the 4-1BB/4-1BBL Pathway in Control of Monocyte Numbers by Invariant NKT Cells
Suzanne L. Cole; Kambez H. Benam; Andrew J. McMichael; Ling-Pei Ho
J Immunol (2014) 192 (8): 3898–3907.
View articletitled, Involvement of the 4-1BB/4-1BBL Pathway in Control of Monocyte Numbers by Invariant NKT Cells
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Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function
Mohammed G. Ghonime; Obada R. Shamaa; Srabani Das; Ramadan A. Eldomany; Teresa Fernandes-Alnemri; Emad S. Alnemri; Mikhail A. Gavrilin; Mark D. Wewers
J Immunol (2014) 192 (8): 3881–3888.
View articletitled, Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function
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Impaired B Cell Receptor Signaling Is Responsible for Reduced TACI Expression and Function in X-Linked Immunodeficient Mice
Kadriye Uslu; Adam S. Coleman; Windy R. Allman; Nora Katsenelson; Richard J. Bram; Kishore R. Alugupalli; Mustafa Akkoyunlu
J Immunol (2014) 192 (8): 3582–3595.
View articletitled, Impaired B Cell Receptor Signaling Is Responsible for Reduced TACI Expression and Function in X-Linked Immunodeficient Mice
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Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells
Julia Geisel; Jürgen Brück; Ivana Glocova; Katja Dengler; Tobias Sinnberg; Oliver Rothfuss; Michael Walter; Klaus Schulze-Osthoff; Martin Röcken; Kamran Ghoreschi
J Immunol (2014) 192 (8): 3530–3539.
View articletitled, Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells
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Differential Role of Th1 and Th2 Cytokines in Autotoxicity Driven by CD19-Specific Second-Generation Chimeric Antigen Receptor T Cells in a Mouse Model
Eleanor J. Cheadle; Victoria Sheard; Dominic G. Rothwell; John S. Bridgeman; Garry Ashton; Vivien Hanson; A. Wasat Mansoor; Robert E. Hawkins; David E. Gilham
J Immunol (2014) 192 (8): 3654–3665.
View articletitled, Differential Role of Th1 and Th2 Cytokines in Autotoxicity Driven by CD19-Specific Second-Generation Chimeric Antigen Receptor T Cells in a Mouse Model
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Distinct Requirements for Activation of NKT and NK Cells during Viral Infection
Aaron J. Tyznik; Shilpi Verma; Qiao Wang; Mitchell Kronenberg; Chris A. Benedict
J Immunol (2014) 192 (8): 3676–3685.
View articletitled, Distinct Requirements for Activation of NKT and NK Cells during Viral Infection
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Histone Deacetylase Inhibitor Sensitizes Apoptosis-Resistant Melanomas to Cytotoxic Human T Lymphocytes through Regulation of TRAIL/DR5 Pathway
Ali R. Jazirehi; Siavash K. Kurdistani; James S. Economou
J Immunol (2014) 192 (8): 3981–3989.
View articletitled, Histone Deacetylase Inhibitor Sensitizes Apoptosis-Resistant Melanomas to Cytotoxic Human T Lymphocytes through Regulation of TRAIL/DR5 Pathway
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NKp46+CD3+ Cells: A Novel Nonconventional T Cell Subset in Cattle Exhibiting Both NK Cell and T Cell Features
Timothy K. Connelley; Cassandra Longhi; Alison Burrells; Kathryn Degnan; Jayne Hope; Alasdair J. Allan; John A. Hammond; Anne K. Storset; W. Ivan Morrison
J Immunol (2014) 192 (8): 3868–3880.
View articletitled, NKp46<sup>+</sup>CD3<sup>+</sup> Cells: A Novel Nonconventional T Cell Subset in Cattle Exhibiting Both NK Cell and T Cell Features
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Chemokine Cooperativity Is Caused by Competitive Glycosaminoglycan Binding
Folkert Verkaar; Jody van Offenbeek; Miranda M. C. van der Lee; Lambertus H. C. J. van Lith; Anne O. Watts; Angelique L. W. M. M. Rops; David C. Aguilar; Joshua J. Ziarek; Johan van der Vlag; Tracy M. Handel; Brian F. Volkman; Amanda E. I. Proudfoot; Henry F. Vischer; Guido J. R. Zaman; Martine J. Smit
J Immunol (2014) 192 (8): 3908–3914.
View articletitled, Chemokine Cooperativity Is Caused by Competitive Glycosaminoglycan Binding
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B Cell Differentiation Is Associated with Reprogramming the CCCTC Binding Factor–Dependent Chromatin Architecture of the Murine MHC Class II Locus
Parimal Majumder; Christopher D. Scharer; Nancy M. Choi; Jeremy M. Boss
J Immunol (2014) 192 (8): 3925–3935.
View articletitled, B Cell Differentiation Is Associated with Reprogramming the CCCTC Binding Factor–Dependent Chromatin Architecture of the Murine MHC Class II Locus
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Hepatic Stellate Cells Orchestrate Clearance of Necrotic Cells in a Hypoxia-Inducible Factor-1α–Dependent Manner by Modulating Macrophage Phenotype in Mice
Akie Mochizuki; Aaron Pace; Cheryl E. Rockwell; Katherine J. Roth; Aaron Chow; Kate M. O’Brien; Ryan Albee; Kara Kelly; Keara Towery; James P. Luyendyk; Bryan L. Copple
J Immunol (2014) 192 (8): 3847–3857.
View articletitled, Hepatic Stellate Cells Orchestrate Clearance of Necrotic Cells in a Hypoxia-Inducible Factor-1α–Dependent Manner by Modulating Macrophage Phenotype in Mice
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Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand
Martin Felices; Todd R. Lenvik; Dave E. M. Ankarlo; Bree Foley; Julie Curtsinger; Xianghua Luo; Bruce R. Blazar; Stephen K. Anderson; Jeffrey S. Miller
J Immunol (2014) 192 (8): 3889–3897.
View articletitled, Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand
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Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
Alfredo Caro-Maldonado; Ruoning Wang; Amanda G. Nichols; Masayuki Kuraoka; Sandra Milasta; Lillian D. Sun; Amanda L. Gavin; E. Dale Abel; Garnett Kelsoe; Douglas R. Green; Jeffrey C. Rathmell
J Immunol (2014) 192 (8): 3626–3636.
View articletitled, Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
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ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma
Marina Miller; Peter Rosenthal; Andrew Beppu; James L. Mueller; Hal M. Hoffman; Arvin B. Tam; Taylor A. Doherty; Matthew D. McGeough; Carla A. Pena; Maho Suzukawa; Maho Niwa; David H. Broide
J Immunol (2014) 192 (8): 3475–3487.
View articletitled, ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma
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Incorporation of CpG into a Liposomal Vaccine Formulation Increases the Maturation of Antigen-Loaded Dendritic Cells and Monocytes To Improve Local and Systemic Immunity
Melanie R. Neeland; Martin J. Elhay; Jackie Nathanielsz; Els N. T. Meeusen; Michael J. de Veer
J Immunol (2014) 192 (8): 3666–3675.
View articletitled, Incorporation of CpG into a Liposomal Vaccine Formulation Increases the Maturation of Antigen-Loaded Dendritic Cells and Monocytes To Improve Local and Systemic Immunity
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Resolvin D1 Stimulates Alveolar Fluid Clearance through Alveolar Epithelial Sodium Channel, Na,K-ATPase via ALX/cAMP/PI3K Pathway in Lipopolysaccharide-Induced Acute Lung Injury
Qian Wang; Xia Zheng; Yang Cheng; Yi-Lan Zhang; Hai-Xu Wen; Zhen Tao; Hui Li; Yu Hao; Ye Gao; Liang-Min Yang; Fang Gao Smith; Chang-Jiang Huang; Sheng-Wei Jin
J Immunol (2014) 192 (8): 3765–3777.
View articletitled, Resolvin D1 Stimulates Alveolar Fluid Clearance through Alveolar Epithelial Sodium Channel, Na,K-ATPase via ALX/cAMP/PI3K Pathway in Lipopolysaccharide-Induced Acute Lung Injury
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Correction: Oral Combined Therapy With Probiotics and Alloantigen Induces B Cell–Dependent Long-Lasting Specific Tolerance
Ana C. T. Mercadante; Suelen M. Perobelli; Ana P. G. Alves; Triciana Gonçalves-Silva; Wallace Mello; Ana C. Gomes-Santos; Anderson Miyoshi; Ana M. C. Faria; Adriana Bonomo
J Immunol (2014) 192 (8): 3990.
View articletitled, Correction: Oral Combined Therapy With Probiotics and Alloantigen Induces B Cell–Dependent Long-Lasting Specific Tolerance
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Polymicrobial Sepsis Alters Antigen-Dependent and -Independent Memory CD8 T Cell Functions
Sean Duong; Stephanie A. Condotta; Deepa Rai; Matthew D. Martin; Thomas S. Griffith; Vladimir P. Badovinac
J Immunol (2014) 192 (8): 3618–3625.
View articletitled, Polymicrobial Sepsis Alters Antigen-Dependent and -Independent Memory CD8 T Cell Functions
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NF90 Exerts Antiviral Activity through Regulation of PKR Phosphorylation and Stress Granules in Infected Cells
Xi Wen; Xiaofeng Huang; Bobo Wing-Yee Mok; Yixin Chen; Min Zheng; Siu-Ying Lau; Pui Wang; Wenjun Song; Dong-Yan Jin; Kwok-Yung Yuen; Honglin Chen
J Immunol (2014) 192 (8): 3753–3764.
View articletitled, NF90 Exerts Antiviral Activity through Regulation of PKR Phosphorylation and Stress Granules in Infected Cells
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Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors
Georgio Kourjian; Yang Xu; Ijah Mondesire-Crump; Mariko Shimada; Pauline Gourdain; Sylvie Le Gall
J Immunol (2014) 192 (8): 3496–3506.
View articletitled, Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors
Supplementary data
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Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization
Christopher Sundling; Zhenhai Zhang; Ganesh E. Phad; Zizhang Sheng; Yimeng Wang; John R. Mascola; Yuxing Li; Richard T. Wyatt; Lawrence Shapiro; Gunilla B. Karlsson Hedestam
J Immunol (2014) 192 (8): 3637–3644.
View articletitled, Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization
Supplementary data
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  • Cover Image

    Cover Image

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    On the cover: The SEM image has been pseudocolored to depict presumed Staphylococcus aureus (golden) on the surface of an orthopedic titanium implant in vivo to model biofilm growth. The implant surface is extensively coated with a matrix material of unknown origin (original magnification ×20,000). Heim, C. E., D. Vidlak, T. D. Scherr, J. A. Kozel, M. Holzapfel, D. E. Muirhead, and T. Kielian. 2014. Myeloid-derived suppressor cells contribute to S. aureus orthopedic biofilm infection. J. Immunol. 192: 3778–3792.
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