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CD4+ T Cell Epitopes of FliC Conserved between Strains of Burkholderia: Implications for Vaccines against Melioidosis and Cepacia Complex in Cystic Fibrosis
Julie A. Musson; Catherine J. Reynolds; Darawan Rinchai; Arnone Nithichanon; Prasong Khaenam; Emmanuel Favry; Natasha Spink; Karen K. Y. Chu; Anthony De Soyza; Gregory J. Bancroft; Ganjana Lertmemongkolchai; Bernard Maillere; Rosemary J. Boyton; Daniel M. Altmann; John H. Robinson
J Immunol (2014) 193 (12): 6041–6049.
Cutting Edge: New Chimeric NOD2/TLR2 Adjuvant Drastically Increases Vaccine Immunogenicity
Vincent Pavot; Nicolas Rochereau; Julien Rességuier; Alice Gutjahr; Christian Genin; Gerard Tiraby; Eric Perouzel; Thierry Lioux; Fabienne Vernejoul; Bernard Verrier; Stéphane Paul
J Immunol (2014) 193 (12): 5781–5785.
NK Cells with KIR2DS2 Immunogenotype Have a Functional Activation Advantage To Efficiently Kill Glioblastoma and Prolong Animal Survival
Andrea Gras Navarro; Justyna Kmiecik; Lina Leiss; Mateusz Zelkowski; Agnete Engelsen; Øystein Bruserud; Jacques Zimmer; Per Øyvind Enger; Martha Chekenya
J Immunol (2014) 193 (12): 6192–6206.
CCAAT/Enhancer-Binding Protein α Negatively Regulates IFN-γ Expression in T Cells
Shinya Tanaka; Kentaro Tanaka; Fay Magnusson; Yeonseok Chung; Gustavo J. Martinez; Yi-hong Wang; Roza I. Nurieva; Tomohiro Kurosaki; Chen Dong
J Immunol (2014) 193 (12): 6152–6160.
Pig Skin Includes Dendritic Cell Subsets Transcriptomically Related to Human CD1a and CD14 Dendritic Cells Presenting Different Migrating Behaviors and T Cell Activation Capacities
Florian Marquet; Thien-Phong Vu Manh; Pauline Maisonnasse; Jamila Elhmouzi-Younes; Céline Urien; Edwige Bouguyon; Luc Jouneau; Mickael Bourge; Gaëlle Simon; Angel Ezquerra; Jérôme Lecardonnel; Michel Bonneau; Marc Dalod; Isabelle Schwartz-Cornil; Nicolas Bertho
J Immunol (2014) 193 (12): 5883–5893.
TRAM Is Required for TLR2 Endosomal Signaling to Type I IFN Induction
Julianne Stack; Sarah L. Doyle; Dympna J. Connolly; Line S. Reinert; Kate M. O’Keeffe; Rachel M. McLoughlin; Søren R. Paludan; Andrew G. Bowie
J Immunol (2014) 193 (12): 6090–6102.
IgG4 and IgE Transcripts in Childhood Allergic Asthma Reflect Divergent Antigen-Driven Selection
Tobias Rogosch; Sebastian Kerzel; Friederike Dey; Johanna-Josophina Wagner; Zhixin Zhang; Rolf F. Maier; Michael Zemlin
J Immunol (2014) 193 (12): 5801–5808.
Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation
Daniel Smrz; Glenn Cruse; Michael A. Beaven; Arnold Kirshenbaum; Dean D. Metcalfe; Alasdair M. Gilfillan
J Immunol (2014) 193 (12): 5924–5932.
Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans
Jean-Baptiste Reiser; François Legoux; Stéphanie Gras; Eric Trudel; Anne Chouquet; Alexandra Léger; Madalen Le Gorrec; Paul Machillot; Marc Bonneville; Xavier Saulquin; Dominique Housset
J Immunol (2014) 193 (12): 5816–5826.
Borrelia burgdorferi Arthritis–Associated Locus Bbaa1 Regulates Lyme Arthritis and K/B×N Serum Transfer Arthritis through Intrinsic Control of Type I IFN Production
Ying Ma; Kenneth K. C. Bramwell; Robert B. Lochhead; Jackie K. Paquette; James F. Zachary; John H. Weis; Cory Teuscher; Janis J. Weis
J Immunol (2014) 193 (12): 6050–6060.
Notch3 Activation Is Sufficient but Not Required for Inducing Human T-Lineage Specification
Els Waegemans; Inge Van de Walle; Jelle De Medts; Magda De Smedt; Tessa Kerre; Bart Vandekerckhove; Georges Leclercq; Tao Wang; Jean Plum; Tom Taghon
J Immunol (2014) 193 (12): 5997–6004.
Intestinal Expression of Fas and Fas Ligand Is Upregulated by Bacterial Signaling through TLR4 and TLR5, with Activation of Fas Modulating Intestinal TLR-Mediated Inflammation
Philana Fernandes; Charlotte O’Donnell; Caitriona Lyons; Jonathan Keane; Tim Regan; Stephen O’Brien; Padraic Fallon; Elizabeth Brint; Aileen Houston
J Immunol (2014) 193 (12): 6103–6113.
The Extracellular Adherence Protein from Staphylococcus aureus Inhibits the Classical and Lectin Pathways of Complement by Blocking Formation of the C3 Proconvertase
Jordan L. Woehl; Daphne A. C. Stapels; Brandon L. Garcia; Kasra X. Ramyar; Andrew Keightley; Maartje Ruyken; Maria Syriga; Georgia Sfyroera; Alexander B. Weber; Michal Zolkiewski; Daniel Ricklin; John D. Lambris; Suzan H. M. Rooijakkers; Brian V. Geisbrecht
J Immunol (2014) 193 (12): 6161–6171.
PARP-1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation
J Immunol (2014) 193 (12): 6114–6123.
Definition of the Cattle Killer Cell Ig–like Receptor Gene Family: Comparison with Aurochs and Human Counterparts
Nicholas D. Sanderson; Paul J. Norman; Lisbeth A. Guethlein; Shirley A. Ellis; Christina Williams; Matthew Breen; Steven D. E. Park; David A. Magee; Farbod Babrzadeh; Andrew Warry; Mick Watson; Daniel G. Bradley; David E. MacHugh; Peter Parham; John A. Hammond
J Immunol (2014) 193 (12): 6016–6030.
TCR Signaling Events Are Required for Maintaining CD4 Regulatory T Cell Numbers and Suppressive Capacities in the Periphery
Arnaud Delpoux; Philippe Yakonowsky; Aurélie Durand; Céline Charvet; Michael Valente; Arnaud Pommier; Nelly Bonilla; Bruno Martin; Cédric Auffray; Bruno Lucas
J Immunol (2014) 193 (12): 5914–5923.
The Specialized Proresolving Mediator 17-HDHA Enhances the Antibody-Mediated Immune Response against Influenza Virus: A New Class of Adjuvant?
Sesquile Ramon; Steven F. Baker; Julie M. Sahler; Nina Kim; Eric A. Feldsott; Charles N. Serhan; Luis Martínez-Sobrido; David J. Topham; Richard P. Phipps
J Immunol (2014) 193 (12): 6031–6040.
Glucocorticoid-Induced Leucine Zipper Enhanced Expression in Dendritic Cells Is Sufficient To Drive Regulatory T Cells Expansion In Vivo
Joseph Calmette; Mehdi Ellouze; Thi Tran; Soumaya Karaki; Emilie Ronin; Francis Capel; Marc Pallardy; Françoise Bachelerie; Roman Krzysiek; Dominique Emilie; Géraldine Schlecht-Louf; Véronique Godot
J Immunol (2014) 193 (12): 5863–5872.
CD4 T Cells Specific for a Latency-Associated γ-Herpesvirus Epitope Are Polyfunctional and Cytotoxic
Michael L. Freeman; Claire E. Burkum; Tres Cookenham; Alan D. Roberts; Kathleen G. Lanzer; Gail E. Huston; Meghan K. Jensen; John Sidney; Bjoern Peters; Jacob E. Kohlmeier; David L. Woodland; Linda F. van Dyk; Alessandro Sette; Marcia A. Blackman
J Immunol (2014) 193 (12): 5827–5834.
Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses
Clayton A. White; Egest J. Pone; Tonika Lam; Connie Tat; Ken L. Hayama; Guideng Li; Hong Zan; Paolo Casali
J Immunol (2014) 193 (12): 5933–5950.
Lipocalin 2 Imparts Selective Pressure on Bacterial Growth in the Bladder and Is Elevated in Women with Urinary Tract Infection
Magnus Steigedal; Anne Marstad; Markus Haug; Jan K. Damås; Roland K. Strong; Pacita L. Roberts; Stephanie D. Himpsl; Ann Stapleton; Thomas M. Hooton; Harry L. T. Mobley; Thomas R. Hawn; Trude H. Flo
J Immunol (2014) 193 (12): 6081–6089.
SLAM–SAP Signaling Promotes Differentiation of IL-17–Producing T Cells and Progression of Experimental Autoimmune Encephalomyelitis
J Immunol (2014) 193 (12): 5841–5853.
Correction: Th17 Cells Contribute to Viral Replication in Coxsackievirus B3-Induced Acute Viral Myocarditis
Jing Yuan; Miao Yu; Qiong-Wen Lin; Ai-Lin Cao; Xian Yu; Ji-Hua Dong; Jin-Ping Wang; Jing-Hui Zhang; Min Wang; He-Ping Guo; Xiang Cheng; Yu-Hua Liao
J Immunol (2014) 193 (12): 6208–6209.
Antibody to the gp120 V1/V2 Loops and CD4+ and CD8+ T Cell Responses in Protection from SIVmac251 Vaginal Acquisition and Persistent Viremia
Shari N. Gordon; Melvin N. Doster; Rhonda C. Kines; Brandon F. Keele; Egidio Brocca-Cofano; Yongjun Guan; Poonam Pegu; Namal P. M. Liyanage; Monica Vaccari; Nicolas Cuburu; Christopher B. Buck; Guido Ferrari; David Montefiori; Michael Piatak, Jr.; Jeffrey D. Lifson; Anastasia M. Xenophontos; David Venzon; Marjorie Robert-Guroff; Barney S. Graham; Douglas R. Lowy; John T. Schiller; Genoveffa Franchini
J Immunol (2014) 193 (12): 6172–6183.
Functions of Heat Shock Proteins in Pathways of the Innate and Adaptive Immune System
J Immunol (2014) 193 (12): 5765–5771.
Cutting Edge: Genetic Variation in TLR1 Is Associated with Pam3CSK4-Induced Effector T Cell Resistance to Regulatory T Cell Suppression
J Immunol (2014) 193 (12): 5786–5790.
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Cover Image
Cover Image
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On the cover: Possible tryptophan conformers of the mutated MelanA/Mart1 peptide (ELAI5W), modeled in the ternary complex between TCR Mel5, MHC molecule HLA-A2, and wild-type peptide. The steric clashes suggest that activation of Mart1-specific T cells by the mutated peptide is allowed after structural adaptation of CDRs to fit the larger residue. Reiser, J.-B., F. Legoux, S. Gras, E. Trudel, A. Chouquet, A. Léger, M. Le Gorrec, P. Machillot, M. Bonneville, X. Saulquin, and D. Housset. 2014. Analysis of relationships between peptide/MHC structural features and naive T cell frequency in humans. J. Immunol. 193: 5816–5826. - PDF Icon PDF LinkFront Matter
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