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15 July 2014
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
LETTERS TO THE EDITOR
BRIEF REVIEWS
ALLERGY AND OTHER HYPERSENSITIVITIES
Elevated Levels of Mast Cells Are Involved in Pruritus Associated with Polycythemia Vera in JAK2V617F Transgenic Mice
J Immunol (2014) 193 (2): 477–484.
The Wnt/β-Catenin Pathway Attenuates Experimental Allergic Airway Disease
Sebastian Reuter; Helen Martin; Hendrik Beckert; Matthias Bros; Evelyn Montermann; Christina Belz; Anke Heinz; Svetlana Ohngemach; Ugur Sahin; Michael Stassen; Roland Buhl; Leonid Eshkind; Christian Taube
J Immunol (2014) 193 (2): 485–495.
GM-CSF–Licensed CD11b+ Lung Dendritic Cells Orchestrate Th2 Immunity to Blomia tropicalis
Qian Zhou; Adrian W. S. Ho; Andreas Schlitzer; Yafang Tang; Kenneth H. S. Wong; Fiona H. S. Wong; Yen Leong Chua; Veronique Angeli; Alessandra Mortellaro; Florent Ginhoux; David M. Kemeny
J Immunol (2014) 193 (2): 496–509.
ANTIGEN RECOGNITION AND RESPONSES
Real-Time Detection of CTL Function Reveals Distinct Patterns of Caspase Activation Mediated by Fas versus Granzyme B
Jinzhu Li; Sarah K. Figueira; Alexandra C. A. Vrazo; Brock F. Binkowski; Braeden L. Butler; Yasuhiro Tabata; Alexandra Filipovich; Michael B. Jordan; Kimberly A. Risma
J Immunol (2014) 193 (2): 519–528.
AUTOIMMUNITY
CLINICAL AND HUMAN IMMUNOLOGY
IMMUNE REGULATION
Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension
Karim C. El Kasmi; Steven C. Pugliese; Suzette R. Riddle; Jens M. Poth; Aimee L. Anderson; Maria G. Frid; Min Li; Soni S. Pullamsetti; Rajkumar Savai; Maria A. Nagel; Mehdi A. Fini; Brian B. Graham; Rubin M. Tuder; Jacob E. Friedman; Holger K. Eltzschig; Ronald J. Sokol; Kurt R. Stenmark
J Immunol (2014) 193 (2): 597–609.
Autotaxin Produced by Stromal Cells Promotes LFA-1–Independent and Rho-Dependent Interstitial T Cell Motility in the Lymph Node Paracortex
J Immunol (2014) 193 (2): 617–626.
Targeting of TLRs Inhibits CD4+ Regulatory T Cell Function and Activates Lymphocytes in Human Peripheral Blood Mononuclear Cells
J Immunol (2014) 193 (2): 627–634.
Human Th2 but Not Th9 Cells Release IL-31 in a STAT6/NF-κB–Dependent Way
J Immunol (2014) 193 (2): 645–654.
IMMUNE SYSTEM DEVELOPMENT
Id1 Expression Promotes T Regulatory Cell Differentiation by Facilitating TCR Costimulation
Chen Liu; Hong-Cheng Wang; Sen Yu; Rong Jin; Hui Tang; Yuan-Feng Liu; Qing Ge; Xiao-Hong Sun; Yu Zhang
J Immunol (2014) 193 (2): 663–672.
IMMUNOTHERAPY AND VACCINES
CD40 Ligand Preferentially Modulates Immune Response and Enhances Protection against Influenza Virus
Anwar M. Hashem; Caroline Gravel; Ze Chen; Yinglei Yi; Monika Tocchi; Bozena Jaentschke; Xingliang Fan; Changgui Li; Michael Rosu-Myles; Alexander Pereboev; Runtao He; Junzhi Wang; Xuguang Li
J Immunol (2014) 193 (2): 722–734.
Autologous Tumor Vaccine Modified with Recombinant New Castle Disease Virus Expressing IL-7 Promotes Antitumor Immune Response
J Immunol (2014) 193 (2): 735–745.
Acute and Chronic B Cell Depletion Disrupts CD4+ and CD8+ T Cell Homeostasis and Expansion during Acute Viral Infection in Mice
Jacquelyn M. Lykken; David J. DiLillo; Eric T. Weimer; Susanne Roser-Page; Mark T. Heise; Jason M. Grayson; M. Neale Weitzmann; Thomas F. Tedder
J Immunol (2014) 193 (2): 746–756.
INFECTIOUS DISEASE AND HOST RESPONSE
Early Lymphoid Responses and Germinal Center Formation Correlate with Lower Viral Load Set Points and Better Prognosis of Simian Immunodeficiency Virus Infection
Jung Joo Hong; Praveen K. Amancha; Kenneth A. Rogers; Cynthia L. Courtney; Colin Havenar-Daughton; Shane Crotty; Aftab A. Ansari; Francois Villinger
J Immunol (2014) 193 (2): 797–806.
Tryptophan Catabolism Restricts IFN-γ–Expressing Neutrophils and Clostridium difficile Immunopathology
Mohamad El-Zaatari; Yu-Ming Chang; Min Zhang; Matthew Franz; Andrew Shreiner; Andrew J. McDermott; Koenraad F. van der Sluijs; René Lutter; Helmut Grasberger; Nobuhiko Kamada; Vincent B. Young; Gary B. Huffnagle; John Y. Kao
J Immunol (2014) 193 (2): 807–816.
Adrenocortical Scavenger Receptor Class B Type I Deficiency Exacerbates Endotoxic Shock and Precipitates Sepsis-Induced Mortality in Mice
Sophie Gilibert; Lauriane Galle-Treger; Martine Moreau; Flora Saint-Charles; Sara Costa; Raphaëlle Ballaire; Philippe Couvert; Alain Carrié; Philippe Lesnik; Thierry Huby
J Immunol (2014) 193 (2): 817–826.
INNATE IMMUNITY AND INFLAMMATION
Opposing Roles of Prostaglandin D2 Receptors in Ulcerative Colitis
Eva M. Sturm; Balazs Radnai; Katharina Jandl; Angela Stančić; Gerald P. Parzmair; Christoph Högenauer; Patrizia Kump; Heimo Wenzl; Wolfgang Petritsch; Thomas R. Pieber; Rufina Schuligoi; Gunther Marsche; Nerea Ferreirós; Akos Heinemann; Rudolf Schicho
J Immunol (2014) 193 (2): 827–839.
PILRα Negatively Regulates Mouse Inflammatory Arthritis
Yonglian Sun; Patrick Caplazi; Juan Zhang; Anita Mazloom; Sarah Kummerfeld; Gabriel Quinones; Kate Senger; Justin Lesch; Ivan Peng; Andrew Sebrell; Wilman Luk; Yanmei Lu; Zhonghua Lin; Kai Barck; Judy Young; Mariela Del Rio; Sophie Lehar; Vida Asghari; WeiYu Lin; Sanjeev Mariathasan; Jason DeVoss; Shahram Misaghi; Mercedesz Balazs; Tao Sai; Benjamin Haley; Philip E. Hass; Min Xu; Wenjun Ouyang; Flavius Martin; Wyne P. Lee; Ali A. Zarrin
J Immunol (2014) 193 (2): 860–870.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles
Laura Esposito; Kara M. D. Hunter; Jan Clark; Daniel B. Rainbow; Helen Stevens; Jennifer Denesha; Simon Duley; Sarah Dawson; Gillian Coleman; Sarah Nutland; Gwynneth L. Bell; Carla Moran; Marcin Pekalski; John A. Todd; Linda S. Wicker
J Immunol (2014) 193 (2): 889–900.
A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels
Wei Luo; Jessica Mayeux; Toni Gutierrez; Lisa Russell; Andrew Getahun; Jennifer Müller; Thomas Tedder; Jane Parnes; Robert Rickert; Lars Nitschke; John Cambier; Anne B. Satterthwaite; Lee Ann Garrett-Sinha
J Immunol (2014) 193 (2): 909–920.
Apurinic/Apyrimidinic Endonuclease 2 Regulates the Expansion of Germinal Centers by Protecting against Activation-Induced Cytidine Deaminase–Independent DNA Damage in B Cells
Jeroen E. J. Guikema; Erin K. Linehan; Nada Esa; Daisuke Tsuchimoto; Yusaku Nakabeppu; Robert T. Woodland; Carol E. Schrader
J Immunol (2014) 193 (2): 931–939.
MUCOSAL IMMUNOLOGY
Human NK Cells Licensed by Killer Ig Receptor Genes Have an Altered Cytokine Program That Modifies CD4+ T Cell Function
Lin Lin; Chao Ma; Bo Wei; Najib Aziz; Raja Rajalingam; Susy Yusung; Henry A. Erlich; Elizabeth A. Trachtenberg; Stephan R. Targan; Dermot P. B. McGovern; James R. Heath; Jonathan Braun
J Immunol (2014) 193 (2): 940–949.
TUMOR IMMUNOLOGY
Reactive Oxygen Species– and DNA Damage Response–Dependent NK Cell Activating Ligand Upregulation Occurs at Transcriptional Levels and Requires the Transcriptional Factor E2F1
Alessandra Soriani; Maria Luisa Iannitto; Biancamaria Ricci; Cinzia Fionda; Giulia Malgarini; Stefania Morrone; Giovanna Peruzzi; Maria Rosaria Ricciardi; Maria Teresa Petrucci; Marco Cippitelli; Angela Santoni
J Immunol (2014) 193 (2): 950–960.
NOVEL IMMUNOLOGICAL METHODS
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Cover Image
Cover Image
On the cover: The digital image shows a tangential section of a colon biopsy from a patient with ulcerative colitis. The section was immunohistochemically stained for one of the prostaglandin D2 receptors, chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2; brown), and counterstained with hematoxylin. Abundant staining can be seen in the inflammatory infiltrates and epithelial cells of the crypts. Sturm, E. M., B. Radnai, K. Jandl, A. Stančić , G. P. Parzmair, C. Högenauer, P. Kump, H. Wenzl, W. Petritsch, T. R. Pieber, R. Schuligoi, G. Marsche, N. Ferreirós, A. Heinemann, and R. Schicho. 2014. Opposing roles of prostaglandin D2 receptors in ulcerative colitis. J. Immunol. 193: 827–839. - PDF Icon PDF LinkFront Matter
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