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Volume 193, Issue 3
1 August 2014
Issue Cover
ISSN 0022-1767
EISSN 1550-6606
In this Issue
Critical Roles of TIPE2 Protein in Murine Experimental Colitis
Yunwei Lou; Honghong Sun; Samantha Morrissey; Thomas Porturas; Suxia Liu; Xianxin Hua; Youhai H. Chen
J Immunol (2014) 193 (3): 1064–1070.
View articletitled, Critical Roles of TIPE2 Protein in Murine Experimental Colitis
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Altered MicroRNA Expression after Infection with Human Cytomegalovirus Leads to TIMP3 Downregulation and Increased Shedding of Metalloprotease Substrates, Including MICA
Gloria Esteso; Elisa Luzón; Elisabeth Sarmiento; Ruth Gómez-Caro; Alexander Steinle; Gillian Murphy; Javier Carbone; Mar Valés-Gómez; Hugh T. Reyburn
J Immunol (2014) 193 (3): 1344–1352.
View articletitled, Altered MicroRNA Expression after Infection with Human Cytomegalovirus Leads to TIMP3 Downregulation and Increased Shedding of Metalloprotease Substrates, Including MICA
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Pseudomonas aeruginosa Quorum-Sensing Molecule Homoserine Lactone Modulates Inflammatory Signaling through PERK and eI-F2α
Mark A. Grabiner; Zhu Fu; Tara Wu; Kevin C. Barry; Christian Schwarzer; Terry E. Machen
J Immunol (2014) 193 (3): 1459–1467.
View articletitled, <em>Pseudomonas aeruginosa</em> Quorum-Sensing Molecule Homoserine Lactone Modulates Inflammatory Signaling through PERK and eI-F2α
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Ammonia Drives Dendritic Cells into Dysfunction
Can Luo; Guobo Shen; Ning Liu; Fengming Gong; Xiawei Wei; Shaohua Yao; Dan Liu; Xiu Teng; Ning Ye; Nan Zhang; Xikun Zhou; Jiong Li; Li Yang; Xia Zhao; Li Yang; Rong Xiang; Yu-quan Wei
J Immunol (2014) 193 (3): 1080–1089.
View articletitled, Ammonia Drives Dendritic Cells into Dysfunction
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Dengue Viral Protease Interaction with NF-κB Inhibitor α/β Results in Endothelial Cell Apoptosis and Hemorrhage Development
Jung-Chen Lin; Shih-Ching Lin; Wen-Yu Chen; Yu-Ting Yen; Chin-Wen Lai; Mi-Hua Tao; Yi-Ling Lin; Shi-Chuen Miaw; Betty A. Wu-Hsieh
J Immunol (2014) 193 (3): 1258–1267.
View articletitled, Dengue Viral Protease Interaction with NF-κB Inhibitor α/β Results in Endothelial Cell Apoptosis and Hemorrhage Development
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25-Hydroxvitamin D3 Promotes the Long-Term Effect of Specific Immunotherapy in a Murine Allergy Model
Guido Heine; Christoph Tabeling; Bjoern Hartmann; Carla R. González Calera; Anja A. Kühl; Juliane Lindner; Andreas Radbruch; Martin Witzenrath; Margitta Worm
J Immunol (2014) 193 (3): 1017–1023.
View articletitled, 25-Hydroxvitamin D<sub>3</sub> Promotes the Long-Term Effect of Specific Immunotherapy in a Murine Allergy Model
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When Less Is More: T Lymphocyte Populations with Restricted Antigen Receptor Diversity
Mitchell Kronenberg
J Immunol (2014) 193 (3): 975–976.
View articletitled, When Less Is More: T Lymphocyte Populations with Restricted Antigen Receptor Diversity
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Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
Jennifer E. Cowan; Nicholas I. McCarthy; Sonia M. Parnell; Andrea J. White; Andrea Bacon; Arnauld Serge; Magali Irla; Peter J. L. Lane; Eric J. Jenkinson; William E. Jenkinson; Graham Anderson
J Immunol (2014) 193 (3): 1204–1212.
View articletitled, Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
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Cutting Edge: CXCR4 Is Critical for CD8+ Memory T Cell Homeostatic Self-Renewal but Not Rechallenge Self-Renewal
Julie Chaix; Simone A. Nish; Wen-Hsuan W. Lin; Nyanza J. Rothman; Lei Ding; E. John Wherry; Steven L. Reiner
J Immunol (2014) 193 (3): 1013–1016.
View articletitled, Cutting Edge: CXCR4 Is Critical for CD8<sup>+</sup> Memory T Cell Homeostatic Self-Renewal but Not Rechallenge Self-Renewal
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Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling
Michael Weitnauer; Lotte Schmidt; Nathalie Ng Kuet Leong; Stephanie Muenchau; Felix Lasitschka; Volker Eckstein; Sabine Hübner; Jan Tuckermann; Alexander H. Dalpke
J Immunol (2014) 193 (3): 1475–1484.
View articletitled, Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling
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Priming of CD8 T Cells by Adenoviral Vectors Is Critically Dependent on B7 and Dendritic Cells but Only Partially Dependent on CD28 Ligation on CD8 T Cells
Karen N. Nielsen; Maria A. Steffensen; Jan P. Christensen; Allan R. Thomsen
J Immunol (2014) 193 (3): 1223–1232.
View articletitled, Priming of CD8 T Cells by Adenoviral Vectors Is Critically Dependent on B7 and Dendritic Cells but Only Partially Dependent on CD28 Ligation on CD8 T Cells
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Integrin-Mediated First Signal for Inflammasome Activation in Intestinal Epithelial Cells
Josephine Thinwa; Jesus A. Segovia; Santanu Bose; Peter H. Dube
J Immunol (2014) 193 (3): 1373–1382.
View articletitled, Integrin-Mediated First Signal for Inflammasome Activation in Intestinal Epithelial Cells
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DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells
Hongbo Lu; Ning Lu; Leiyun Weng; Bin Yuan; Yong-jun Liu; Zhiqiang Zhang
J Immunol (2014) 193 (3): 1364–1372.
View articletitled, DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells
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The Receptor for the Complement C3a Anaphylatoxin (C3aR) Provides Host Protection against Listeria monocytogenes–Induced Apoptosis
Stacey L. Mueller-Ortiz; John E. Morales; Rick A. Wetsel
J Immunol (2014) 193 (3): 1278–1289.
View articletitled, The Receptor for the Complement C3a Anaphylatoxin (C3aR) Provides Host Protection against <em>Listeria monocytogenes</em>–Induced Apoptosis
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Expression of the Mouse MHC Class Ib H2-T11 Gene Product, a Paralog of H2-T23 (Qa-1) with Shared Peptide-Binding Specificity
Lili Chen; Eduardo Reyes-Vargas; Hu Dai; Hernando Escobar; Brant Rudd; Jared Fairbanks; Alexander Ho; Mathew F. Cusick; Attila Kumánovics; Julio Delgado; Xiao He; Peter E. Jensen
J Immunol (2014) 193 (3): 1427–1439.
View articletitled, Expression of the Mouse MHC Class Ib H2-T11 Gene Product, a Paralog of H2-T23 (Qa-1) with Shared Peptide-Binding Specificity
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Prolonged Triglyceride Storage in Macrophages: pHo Trumps pO2 and TLR4
Mingfang Lu; Terry Kho; Robert S. Munford
J Immunol (2014) 193 (3): 1392–1397.
View articletitled, Prolonged Triglyceride Storage in Macrophages: pH<sub>o</sub> Trumps pO<sub>2</sub> and TLR4
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Intestinal Inflammation Modulates Expression of the Iron-Regulating Hormone Hepcidin Depending on Erythropoietic Activity and the Commensal Microbiota
Nanda Kumar N. Shanmugam; Estela Trebicka; Ling-lin Fu; Hai Ning Shi; Bobby J. Cherayil
J Immunol (2014) 193 (3): 1398–1407.
View articletitled, Intestinal Inflammation Modulates Expression of the Iron-Regulating Hormone Hepcidin Depending on Erythropoietic Activity and the Commensal Microbiota
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Mode of Delivery Shapes Gut Colonization Pattern and Modulates Regulatory Immunity in Mice
Camilla H. F. Hansen; Line S. F. Andersen; Łukasz Krych; Stine B. Metzdorff; Jane P. Hasselby; Søren Skov; Dennis S. Nielsen; Karsten Buschard; Lars H. Hansen; Axel K. Hansen
J Immunol (2014) 193 (3): 1213–1222.
View articletitled, Mode of Delivery Shapes Gut Colonization Pattern and Modulates Regulatory Immunity in Mice
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CXCL1 Inhibits Airway Smooth Muscle Cell Migration through the Decoy Receptor Duffy Antigen Receptor for Chemokines
Laila A. Al-Alwan; Ying Chang; Simon Rousseau; James G. Martin; David H. Eidelman; Qutayba Hamid
J Immunol (2014) 193 (3): 1416–1426.
View articletitled, CXCL1 Inhibits Airway Smooth Muscle Cell Migration through the Decoy Receptor Duffy Antigen Receptor for Chemokines
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Antigen-Pulsed Bone Marrow–Derived and Pulmonary Dendritic Cells Promote Th2 Cell Responses and Immunopathology in Lungs during the Pathogenesis of Murine Mycoplasma Pneumonia
Nicole A. Dobbs; Xia Zhou; Mark Pulse; Lisa M. Hodge; Trenton R. Schoeb; Jerry W. Simecka
J Immunol (2014) 193 (3): 1353–1363.
View articletitled, Antigen-Pulsed Bone Marrow–Derived and Pulmonary Dendritic Cells Promote Th2 Cell Responses and Immunopathology in Lungs during the Pathogenesis of Murine Mycoplasma Pneumonia
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Enhancement of Tumor-Specific T Cell–Mediated Immunity in Dendritic Cell–Based Vaccines by Mycobacterium tuberculosis Heat Shock Protein X
In Duk Jung; Sung Jae Shin; Min-Goo Lee; Tae Heung Kang; Hee Dong Han; Seung Jun Lee; Woo Sik Kim; Hong Min Kim; Won Sun Park; Han Wool Kim; Cheol-Heui Yun; Eun Kyung Lee; T.-C. Wu; Yeong-Min Park
J Immunol (2014) 193 (3): 1233–1245.
View articletitled, Enhancement of Tumor-Specific T Cell–Mediated Immunity in Dendritic Cell–Based Vaccines by <em>Mycobacterium tuberculosis</em> Heat Shock Protein X
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Mucosal Polyinosinic-Polycytidylic Acid Improves Protection Elicited by Replicating Influenza Vaccines via Enhanced Dendritic Cell Function and T Cell Immunity
José V. Pérez-Girón; Alan Belicha-Villanueva; Ebrahim Hassan; Sergio Gómez-Medina; Jazmina L. G. Cruz; Anja Lüdtke; Paula Ruibal; Randy A. Albrecht; Adolfo García-Sastre; César Muñoz-Fontela
J Immunol (2014) 193 (3): 1324–1332.
View articletitled, Mucosal Polyinosinic-Polycytidylic Acid Improves Protection Elicited by Replicating Influenza Vaccines via Enhanced Dendritic Cell Function and T Cell Immunity
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The Eμ Enhancer Region Influences H Chain Expression and B Cell Fate without Impacting IgVH Repertoire and Immune Response In Vivo
Marie Marquet; Armand Garot; Sébastien Bender; Claire Carrion; Pauline Rouaud; Sandrine Lecardeur; Yves Denizot; Michel Cogné; Eric Pinaud
J Immunol (2014) 193 (3): 1171–1183.
View articletitled, The Eμ Enhancer Region Influences H Chain Expression and B Cell Fate without Impacting IgV<sub>H</sub> Repertoire and Immune Response In Vivo
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A Negative Feedback Loop Mediated by STAT3 Limits Human Th17 Responses
Harriet A. Purvis; Amy E. Anderson; David A. Young; John D. Isaacs; Catharien M. U. Hilkens
J Immunol (2014) 193 (3): 1142–1150.
View articletitled, A Negative Feedback Loop Mediated by STAT3 Limits Human Th17 Responses
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Genetic Control of Susceptibility to Candida albicans in SM/J Mice
Irena Radovanovic; Vicki Leung; Alexandra Iliescu; Silayuv E. Bongfen; Alaka Mullick; David Langlais; Philippe Gros
J Immunol (2014) 193 (3): 1290–1300.
View articletitled, Genetic Control of Susceptibility to <em>Candida albicans</em> in SM/J Mice
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The Majority of Human Memory B Cells Recognizing RhD and Tetanus Resides in IgM+ B Cells
Luciana Della Valle; Serge E. Dohmen; Onno J. H. M. Verhagen; Magdalena A. Berkowska; Gestur Vidarsson; C. Ellen van der Schoot
J Immunol (2014) 193 (3): 1071–1079.
View articletitled, The Majority of Human Memory B Cells Recognizing RhD and Tetanus Resides in IgM<sup>+</sup> B Cells
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IFN Regulatory Factor 10 Is a Negative Regulator of the IFN Responses in Fish
Shun Li; Long-Feng Lu; Hong Feng; Nan Wu; Dan-Dan Chen; Yi-Bing Zhang; Jian-Fang Gui; Pin Nie; Yong-An Zhang
J Immunol (2014) 193 (3): 1100–1109.
View articletitled, IFN Regulatory Factor 10 Is a Negative Regulator of the IFN Responses in Fish
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Dendritic Cells and Anergic Type I NKT Cells Play a Crucial Role in Sulfatide-Mediated Immune Regulation in Experimental Autoimmune Encephalomyelitis
Igor Maricic; Ramesh Halder; Felix Bischof; Vipin Kumar
J Immunol (2014) 193 (3): 1035–1046.
View articletitled, Dendritic Cells and Anergic Type I NKT Cells Play a Crucial Role in Sulfatide-Mediated Immune Regulation in Experimental Autoimmune Encephalomyelitis
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Proteasome Inhibition with Bortezomib Depletes Plasma Cells and Specific Autoantibody Production in Primary Thymic Cell Cultures from Early-Onset Myasthenia Gravis Patients
Alejandro M. Gomez; Nick Willcox; Kathleen Vrolix; Jonas Hummel; Gisela Nogales-Gadea; Abhishek Saxena; Hans Duimel; Fons Verheyen; Peter C. Molenaar; Wim A. Buurman; Marc H. De Baets; Pilar Martinez-Martinez; Mario Losen
J Immunol (2014) 193 (3): 1055–1063.
View articletitled, Proteasome Inhibition with Bortezomib Depletes Plasma Cells and Specific Autoantibody Production in Primary Thymic Cell Cultures from Early-Onset Myasthenia Gravis Patients
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Immunoproteasomes Shape the Transcriptome and Regulate the Function of Dendritic Cells
Danielle A. de Verteuil; Alexandre Rouette; Marie-Pierre Hardy; Stéphanie Lavallée; Assya Trofimov; Étienne Gaucher; Claude Perreault
J Immunol (2014) 193 (3): 1121–1132.
View articletitled, Immunoproteasomes Shape the Transcriptome and Regulate the Function of Dendritic Cells
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Systemic Response to Ultraviolet Radiation Involves Induction of Leukocytic IL-1β and Inflammation in Zebrafish
Sanjita Banerjee; Maria Leptin
J Immunol (2014) 193 (3): 1408–1415.
View articletitled, Systemic Response to Ultraviolet Radiation Involves Induction of Leukocytic IL-1β and Inflammation in Zebrafish
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Differentiation of IL-17–Producing Effector and Regulatory Human T Cells from Lineage-Committed Naive Precursors
Frances Mercer; Alka Khaitan; Lina Kozhaya; Judith A. Aberg; Derya Unutmaz
J Immunol (2014) 193 (3): 1047–1054.
View articletitled, Differentiation of IL-17–Producing Effector and Regulatory Human T Cells from Lineage-Committed Naive Precursors
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Local Immune Response to Injection of Plasmodium Sporozoites into the Skin
Laura Mac-Daniel; Matthew R. Buckwalter; Michèle Berthet; Yasemin Virk; Katsuyuki Yui; Matthew L. Albert; Pascale Gueirard; Robert Ménard
J Immunol (2014) 193 (3): 1246–1257.
View articletitled, Local Immune Response to Injection of <em>Plasmodium</em> Sporozoites into the Skin
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Human Hematopoietic Reconstitution and HLA-Restricted Responses in Nonpermissive Alymphoid Mice
Malika Serra-Hassoun; Maryline Bourgine; Michele Boniotto; Julien Berges; Francina Langa; Marie-Louise Michel; Antonio A. Freitas; Sylvie Garcia
J Immunol (2014) 193 (3): 1504–1511.
View articletitled, Human Hematopoietic Reconstitution and HLA-Restricted Responses in Nonpermissive Alymphoid Mice
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miR-190b Is Markedly Upregulated in the Intestine in Response to Simian Immunodeficiency Virus Replication and Partly Regulates Myotubularin-Related Protein-6 Expression
Mahesh Mohan; Lawrance C. Chandra; Workineh Torben; Pyone P. Aye; Xavier Alvarez; Andrew A. Lackner
J Immunol (2014) 193 (3): 1301–1313.
View articletitled, miR-190b Is Markedly Upregulated in the Intestine in Response to Simian Immunodeficiency Virus Replication and Partly Regulates Myotubularin-Related Protein-6 Expression
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Nitric Oxide Regulates BAFF Expression and T Cell–Independent Antibody Responses
Daniela Giordano; Kevin E. Draves; Chang Li; Tobias M. Hohl; Edward A. Clark
J Immunol (2014) 193 (3): 1110–1120.
View articletitled, Nitric Oxide Regulates BAFF Expression and T Cell–Independent Antibody Responses
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IκB Kinase Activity Drives Fetal Lung Macrophage Maturation along a Non-M1/M2 Paradigm
Ashley N. Stouch; Rinat Zaynagetdinov; Whitney J. Barham; Amanda M. Stinnett; James C. Slaughter; Fiona E. Yull; Hal M. Hoffman; Timothy S. Blackwell; Lawrence S. Prince
J Immunol (2014) 193 (3): 1184–1193.
View articletitled, <strong>IκB Kinase Activity Drives Fetal Lung Macrophage Maturation along a Non-M1/M2 Paradigm</strong>
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Mismatch Repair Proteins and AID Activity Are Required for the Dominant Negative Function of C-Terminally Deleted AID in Class Switching
Anna J. Ucher; Sanjay Ranjit; Tatenda Kadungure; Erin K. Linehan; Lyne Khair; Elaine Xie; Jennifer Limauro; Katherina S. Rauch; Carol E. Schrader; Janet Stavnezer
J Immunol (2014) 193 (3): 1440–1450.
View articletitled, Mismatch Repair Proteins and AID Activity Are Required for the Dominant Negative Function of C-Terminally Deleted AID in Class Switching
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Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop
Thies Rösner; Stefan Lohse; Matthias Peipp; Thomas Valerius; Stefanie Derer
J Immunol (2014) 193 (3): 1485–1495.
View articletitled, Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop
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Vitamin D Inhibits the Occurrence of Experimental Cerebral Malaria in Mice by Suppressing the Host Inflammatory Response
Xiyue He; Juan Yan; Xiaotong Zhu; Qinghui Wang; Wei Pang; Zanmei Qi; Meilian Wang; Enjie Luo; Daniel M. Parker; Margherita T. Cantorna; Liwang Cui; Yaming Cao
J Immunol (2014) 193 (3): 1314–1323.
View articletitled, Vitamin D Inhibits the Occurrence of Experimental Cerebral Malaria in Mice by Suppressing the Host Inflammatory Response
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Mammalian Target of Rapamycin Complex 2 Modulates αβTCR Processing and Surface Expression during Thymocyte Development
Po-Chien Chou; Won Jun Oh; Chang-Chih Wu; Joseph Moloughney; Markus A. Rüegg; Michael N. Hall; Estela Jacinto; Guy Werlen
J Immunol (2014) 193 (3): 1162–1170.
View articletitled, Mammalian Target of Rapamycin Complex 2 Modulates αβTCR Processing and Surface Expression during Thymocyte Development
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Murine Spleen Tissue Regeneration from Neonatal Spleen Capsule Requires Lymphotoxin Priming of Stromal Cells
Jonathan K. H. Tan; Takeshi Watanabe
J Immunol (2014) 193 (3): 1194–1203.
View articletitled, Murine Spleen Tissue Regeneration from Neonatal Spleen Capsule Requires Lymphotoxin Priming of Stromal Cells
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Regulation of Osteoclast Homeostasis and Inflammatory Bone Loss by MFG-E8
Toshiharu Abe; Jieun Shin; Kavita Hosur; Mark C. Udey; Triantafyllos Chavakis; George Hajishengallis
J Immunol (2014) 193 (3): 1383–1391.
View articletitled, Regulation of Osteoclast Homeostasis and Inflammatory Bone Loss by MFG-E8
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RAG1/2 Knockout Pigs with Severe Combined Immunodeficiency
Jiao Huang; Xiaogang Guo; Nana Fan; Jun Song; Bentian Zhao; Zhen Ouyang; Zhaoming Liu; Yu Zhao; Quanmei Yan; Xiaoling Yi; Axel Schambach; Jon Frampton; Miguel A. Esteban; Dongshan Yang; Huaqiang Yang; Liangxue Lai
J Immunol (2014) 193 (3): 1496–1503.
View articletitled, RAG1/2 Knockout Pigs with Severe Combined Immunodeficiency
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Histone Deacetylation Critically Determines T Cell Subset Radiosensitivity
Jason L. Pugh; Alona S. Sukhina; Thomas M. Seed; Nancy R. Manley; Gregory D. Sempowski; Marcel R. M. van den Brink; Megan J. Smithey; Janko Nikolich-Žugich
J Immunol (2014) 193 (3): 1451–1458.
View articletitled, Histone Deacetylation Critically Determines T Cell Subset Radiosensitivity
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Increased IFN-α–Producing Plasmacytoid Dendritic Cells (pDCs) in Human Th1-Mediated Type 1 Diabetes: pDCs Augment Th1 Responses through IFN-α Production
Chang-Qing Xia; Ruihua Peng; Anna V. Chernatynskaya; Lihui Yuan; Carolyn Carter; John Valentine; Eric Sobel; Mark A. Atkinson; Michael J. Clare-Salzler
J Immunol (2014) 193 (3): 1024–1034.
View articletitled, Increased IFN-α–Producing Plasmacytoid Dendritic Cells (pDCs) in Human Th1-Mediated Type 1 Diabetes: pDCs Augment Th1 Responses through IFN-α Production
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Immune Suppression via Glucocorticoid-Stimulated Monocytes: A Novel Mechanism To Cope with Inflammation
Georg Varga; Jan Ehrchen; Anne Brockhausen; Toni Weinhage; Nadine Nippe; Michael Belz; Athanasios Tsianakas; Matthias Ross; Dominik Bettenworth; Tilmann Spieker; Marc Wolf; Ralph Lippe; Klaus Tenbrock; Pieter J. M. Leenen; Johannes Roth; Cord Sunderkötter
J Immunol (2014) 193 (3): 1090–1099.
View articletitled, Immune Suppression via Glucocorticoid-Stimulated Monocytes: A Novel Mechanism To Cope with Inflammation
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Correction: Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-γ and GM-CSF
Paul Spear; Amorette Barber; Agnieszka Rynda-Apple; Charles L. Sentman
J Immunol (2014) 193 (3): 1513.
View articletitled, Correction: Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-γ and GM-CSF
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CXCL17 Is a Major Chemotactic Factor for Lung Macrophages
Amanda M. Burkhardt; José L. Maravillas-Montero; Christina D. Carnevale; Natalia Vilches-Cisneros; Juan P. Flores; Peter A. Hevezi; Albert Zlotnik
J Immunol (2014) 193 (3): 1468–1474.
View articletitled, CXCL17 Is a Major Chemotactic Factor for Lung Macrophages
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Klebsiella pneumoniae Alleviates Influenza-Induced Acute Lung Injury via Limiting NK Cell Expansion
Jian Wang; Fengqi Li; Rui Sun; Xiang Gao; Haiming Wei; Zhigang Tian
J Immunol (2014) 193 (3): 1133–1141.
View articletitled, <em>Klebsiella pneumoniae</em> Alleviates Influenza-Induced Acute Lung Injury via Limiting NK Cell Expansion
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Conventional but Not Plasmacytoid Dendritic Cells Foster the Systemic Virus–Induced Type I IFN Response Needed for Efficient CD8 T Cell Priming
Sandra Hervas-Stubbs; Jose-Ignacio Riezu-Boj; Uxua Mancheño; Paloma Rueda; Lissette Lopez; Diego Alignani; Estefanía Rodríguez-García; Nathalie Thieblemont; Claude Leclerc
J Immunol (2014) 193 (3): 1151–1161.
View articletitled, Conventional but Not Plasmacytoid Dendritic Cells Foster the Systemic Virus–Induced Type I IFN Response Needed for Efficient CD8 T Cell Priming
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Pillars Article: Homogenous Junctional Sequence of the V14+ T-Cell Antigen Receptor α Chain Expanded in Unprimed Mice. Proc. Natl. Acad. Sci. U.S.A. 1990. 87: 5248–5252
Haruhiko Koseki; Kenji Imai; Fumiaki Nakayama; Toshihiko Sado; Kazuro Moriwaki; Masaru Taniguchi
J Immunol (2014) 193 (3): 993–997.
View articletitled, Pillars Article: Homogenous Junctional Sequence of the V14<sup>+</sup> T-Cell Antigen Receptor α Chain Expanded in Unprimed Mice. <em>Proc. Natl. Acad. Sci. U.S.A.</em> 1990. 87: 5248–5252
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Pillars Article: Analysis of T Cell Antigen Receptor (TCR) Expression by Human Peripheral Blood CD4−8− α/β T Cells Demonstrates Preferential Use of Several Vβ Genes and an Invariant TCR α Chain. J. Exp. Med. 1993. 178: 1–16
Steven Porcelli; Courtland E. Yockey; Michael B. Brenner; Steven P. Balk
J Immunol (2014) 193 (3): 977–992.
View articletitled, Pillars Article: Analysis of T Cell Antigen Receptor (TCR) Expression by Human Peripheral Blood CD4<sup>−</sup>8<sup>−</sup> α/β T Cells Demonstrates Preferential Use of Several Vβ Genes and an Invariant TCR α Chain. <em>J. Exp. Med.</em> 1993. 178: 1–16
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Artesunate versus Chloroquine Infection–Treatment–Vaccination Defines Stage-Specific Immune Responses Associated with Prolonged Sterile Protection against Both Pre-erythrocytic and Erythrocytic Plasmodium yoelii Infection
Xiaohong Peng; Gladys J. Keitany; Marissa Vignali; Lin Chen; Claire Gibson; Kimberly Choi; Fusheng Huang; Ruobing Wang
J Immunol (2014) 193 (3): 1268–1277.
View articletitled, Artesunate versus Chloroquine Infection–Treatment–Vaccination Defines Stage-Specific Immune Responses Associated with Prolonged Sterile Protection against Both Pre-erythrocytic and Erythrocytic <em>Plasmodium yoelii</em> Infection
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Correction: Immunotherapy with Chimeric NKG2D Receptors Leads to Long-Term Tumor-Free Survival and Development of Host Antitumor Immunity in Murine Ovarian Cancer
Amorette Barber; Tong Zhang; Charles L. Sentman
J Immunol (2014) 193 (3): 1513.
View articletitled, Correction: Immunotherapy with Chimeric NKG2D Receptors Leads to Long-Term Tumor-Free Survival and Development of Host Antitumor Immunity in Murine Ovarian Cancer
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Correction: Critical Role of p38 and GATA3 in Natural Helper Cell Function
Jun-ichi Furusawa; Kazuyo Moro; Yasutaka Motomura; Kazuo Okamoto; Jinfang Zhu; Hiroshi Takayanagi; Masato Kubo; Shigeo Koyasu
J Immunol (2014) 193 (3): 1512.
View articletitled, Correction: Critical Role of p38 and GATA3 in Natural Helper Cell Function
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Roles and Regulation of Gastrointestinal Eosinophils in Immunity and Disease
YunJae Jung; Marc E. Rothenberg
J Immunol (2014) 193 (3): 999–1005.
View articletitled, Roles and Regulation of Gastrointestinal Eosinophils in Immunity and Disease
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Correction: Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment
Amorette Barber; Agnieszka Rynda; Charles L. Sentman
J Immunol (2014) 193 (3): 1513.
View articletitled, Correction: Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment
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Correction: Chimeric NKG2D T Cells Require Both T Cell- and Host-Derived Cytokine Secretion and Perforin Expression to Increase Tumor Antigen Presentation and Systemic Immunity
Amorette Barber; Charles L. Sentman
J Immunol (2014) 193 (3): 1513.
View articletitled, Correction: Chimeric NKG2D T Cells Require Both T Cell- and Host-Derived Cytokine Secretion and Perforin Expression to Increase Tumor Antigen Presentation and Systemic Immunity
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HDAC8-Mediated Epigenetic Reprogramming Plays a Key Role in Resistance to Anthrax Lethal Toxin–Induced Pyroptosis in Macrophages
Soon-Duck Ha; Chae Young Han; Chantelle Reid; Sung Ouk Kim
J Immunol (2014) 193 (3): 1333–1343.
View articletitled, HDAC8-Mediated Epigenetic Reprogramming Plays a Key Role in Resistance to Anthrax Lethal Toxin–Induced Pyroptosis in Macrophages
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In This Issue
J Immunol (2014) 193 (3): 973–974.
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Dendritic Cell–Derived Exosomes as Immunotherapies in the Fight against Cancer
Jonathan M. Pitt; Mélinda Charrier; Sophie Viaud; Fabrice André; Benjamin Besse; Nathalie Chaput; Laurence Zitvogel
J Immunol (2014) 193 (3): 1006–1011.
View articletitled, Dendritic Cell–Derived Exosomes as Immunotherapies in the Fight against Cancer
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  • Cover Image

    Cover Image

    issue cover
    On the cover: Coronal section of a tooth and periodontal tissue from a mouse lacking MFG-E8, a novel homeostatic regulator of osteoclasts. MFG-E8–deficient mice exhibit enhanced osteoclastogenesis and bone loss in periodontitis (note nearly total loss of bone support) compared with wild-type controls. Specimen stained with tartrate-resistant acid phosphatase, hematoxylin, orange-G, and aniline blue. Abe, T., J. Shin, K. Hosur, M. C. Udey, T. Chavakis, and G. Hajishengallis. 2014. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8. J. Immunol. 193: 1383–1391.
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  • Online ISSN 1550-6606
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