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1 December 2015
ISSN 0022-1767
EISSN 1550-6606
In this Issue
PRESIDENT'S ADDRESS
IN THIS ISSUE
LETTERS TO THE EDITOR
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
ANTIGEN RECOGNITION AND RESPONSES
IL-21 and IL-4 Collaborate To Shape T-Dependent Antibody Responses
Helen M. McGuire; Alexis Vogelzang; Joanna Warren; Claudia Loetsch; Karlo D. Natividad; Tyani D. Chan; Robert Brink; Marcel Batten; Cecile King
J Immunol (2015) 195 (11): 5123–5135.
AUTOIMMUNITY
CLINICAL AND HUMAN IMMUNOLOGY
Identification of Cell Surface Straight Chain Poly-N-Acetyl-Lactosamine Bearing Protein Ligands for VH4-34–Encoded Natural IgM Antibodies
J Immunol (2015) 195 (11): 5178–5188.
IMMUNE REGULATION
Antagonizing Peroxisome Proliferator–Activated Receptor α Activity Selectively Enhances Th1 Immunity in Male Mice
Monan Angela Zhang; Jeeyoon Jennifer Ahn; Fei Linda Zhao; Thirumahal Selvanantham; Thierry Mallevaey; Nick Stock; Lucia Correa; Ryan Clark; David Spaner; Shannon E. Dunn
J Immunol (2015) 195 (11): 5189–5202.
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow–Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation
Peter I. Lobo; Kailo H. Schlegel; Amandeep Bajwa; Liping Huang; Elvira Kurmaeva; Binru Wang; Hong Ye; Thomas F. Tedder; Gilbert R. Kinsey; Mark D. Okusa
J Immunol (2015) 195 (11): 5215–5226.
Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell–Mediated Control of T Cell Immunity
J Immunol (2015) 195 (11): 5237–5250.
IMMUNE SYSTEM DEVELOPMENT
INFECTIOUS DISEASE AND HOST RESPONSE
INNATE IMMUNITY AND INFLAMMATION
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women
Morgane Griesbeck; Susanne Ziegler; Sophie Laffont; Nikaïa Smith; Lise Chauveau; Phillip Tomezsko; Armon Sharei; Georgio Kourjian; Filippos Porichis; Meghan Hart; Christine D. Palmer; Michael Sirignano; Claudia Beisel; Heike Hildebrandt; Claire Cénac; Alexandra-Chloé Villani; Thomas J. Diefenbach; Sylvie Le Gall; Olivier Schwartz; Jean-Philippe Herbeuval; Brigitte Autran; Jean-Charles Guéry; J. Judy Chang; Marcus Altfeld
J Immunol (2015) 195 (11): 5327–5336.
Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis
J Immunol (2015) 195 (11): 5337–5346.
MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN
J Immunol (2015) 195 (11): 5404–5414.
A Truncated Variant of ASCC1, a Novel Inhibitor of NF-κB, Is Associated with Disease Severity in Patients with Rheumatoid Arthritis
Silvia Torices; Lorena Alvarez-Rodríguez; Lara Grande; Ignacio Varela; Pedro Muñoz; Dora Pascual; Alejandro Balsa; Marcos López-Hoyos; Víctor Martinez-Taboada; Jose L. Fernández-Luna
J Immunol (2015) 195 (11): 5415–5420.
Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism
Dominik Stammler; Tatjana Eigenbrod; Sarah Menz; Julia S. Frick; Matthew J. Sweet; Melanie R. Shakespear; Jonathan Jantsch; Isabel Siegert; Sabine Wölfle; Julian D. Langer; Ina Oehme; Liliana Schaefer; Andre Fischer; Judith Knievel; Klaus Heeg; Alexander H. Dalpke; Konrad A. Bode
J Immunol (2015) 195 (11): 5421–5431.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Characterization of Lamprey IL-17 Family Members and Their Receptors
Qifeng Han; Sabyasachi Das; Masayuki Hirano; Stephen J. Holland; Nathanael McCurley; Peng Guo; Charles S. Rosenberg; Thomas Boehm; Max D. Cooper
J Immunol (2015) 195 (11): 5440–5451.
Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination
J Immunol (2015) 195 (11): 5461–5471.
Revisiting the Timing of Action of the PAG Adaptor Using Quantitative Proteomics Analysis of Primary T Cells
Kavita Reginald; Karima Chaoui; Romain Roncagalli; Mathilde Beau; Marisa Goncalves Menoita; Bernard Monsarrat; Odile Burlet-Schiltz; Marie Malissen; Anne Gonzalez de Peredo; Bernard Malissen
J Immunol (2015) 195 (11): 5472–5481.
TUMOR IMMUNOLOGY
NOVEL IMMUNOLOGICAL METHODS
Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors
Alison L. Tutt; Sonya James; Stéphanie A. Laversin; Thomas R. W. Tipton; Margaret Ashton-Key; Ruth R. French; Khiyam Hussain; Andrew T. Vaughan; Lang Dou; Alexander Earley; Lekh N. Dahal; Chen Lu; Melanie Dunscombe; H. T. Claude Chan; Christine A. Penfold; Jinny H. Kim; Elizabeth A. Potter; C. Ian Mockridge; Ali Roghanian; Robert J. Oldham; Kerry L. Cox; Sean H. Lim; Ingrid Teige; Bjorn Frendéus; Martin J. Glennie; Stephen A. Beers; Mark S. Cragg
J Immunol (2015) 195 (11): 5503–5516.
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Cover Image
Cover Image
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On the cover: Histologic section of human spleen immunostained for FcγRIIB (brown) and CD20 (B cells, red). Human FcγRIIB is strongly expressed on B cells in the splenic follicles. Original magnification ×20. Tutt, A. L., S. James, S. A. Laversin, T. R. W. Tipton, M. Ashton-Key, R. R. French, K. Hussain, A. T. Vaughan, L. Dou, A. Earley, L. N. Dahal, C. Lu, M. Dunscombe, H. T. C. Chan, C. A. Penfold, J. H. Kim, E. A. Potter, C. I. Mockridge, A. Roghanian, R. J. Oldham, K. L. Cox, S. H. Lim, I. Teige, B. Frendéus, M. J. Glennie, S. A. Beers, and M. S. Cragg. 2015. Development and characterization of monoclonal antibodies specific for mouse and human Fcγ receptors. J. Immunol. 195: 5503–5516.
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