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15 August 2016
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: B Cell–Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection
Burton E. Barnett; Ryan P. Staupe; Pamela M. Odorizzi; Olesya Palko; Vesselin T. Tomov; Alison E. Mahan; Bronwyn Gunn; Diana Chen; Michael A. Paley; Galit Alter; Steven L. Reiner; Georg M. Lauer; John R. Teijaro; E. John Wherry
J Immunol (2016) 197 (4): 1017–1022.
Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells
Martin S. Naradikian; Arpita Myles; Daniel P. Beiting; Kenneth J. Roberts; Lucas Dawson; Ramin Sedaghat Herati; Bertram Bengsch; Susanne L. Linderman; Erietta Stelekati; Rosanne Spolski; E. John Wherry; Christopher Hunter; Scott E. Hensley; Warren J. Leonard; Michael P. Cancro
J Immunol (2016) 197 (4): 1023–1028.
ANTIGEN RECOGNITION AND RESPONSES
AUTOIMMUNITY
TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
Lukas Bossaller; Anette Christ; Karin Pelka; Kerstin Nündel; Ping-I Chiang; Catherine Pang; Neha Mishra; Patricia Busto; Ramon G. Bonegio; Reinhold Ernst Schmidt; Eicke Latz; Ann Marshak-Rothstein
J Immunol (2016) 197 (4): 1044–1053.
Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis
Pan Su; Sheng Chen; Yu Han Zheng; Hai Yan Zhou; Cheng Hua Yan; Fang Yu; Ya Guang Zhang; Lan He; Yuan Zhang; Yanming Wang; Lei Wu; Xiaoai Wu; Bingke Yu; Li Yan Ma; Zhiru Yang; Jianhua Wang; Guixian Zhao; Jinfang Zhu; Zhi-Ying Wu; Bing Sun
J Immunol (2016) 197 (4): 1054–1064.
Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6
Michael Jeffrey Cho; Christoph T. Ellebrecht; Christoph M. Hammers; Eric M. Mukherjee; Gopal Sapparapu; Crystal E. Boudreaux; Sarah M. McDonald; James E. Crowe, Jr.; Aimee S. Payne
J Immunol (2016) 197 (4): 1065–1073.
Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein
S. Anwar Jagessar; Inge R. Holtman; Sam Hofman; Elena Morandi; Nicole Heijmans; Jon D. Laman; Bruno Gran; Bart W. Faber; Sander I. van Kasteren; Bart J. L. Eggen; Bert A. ‘t Hart
J Immunol (2016) 197 (4): 1074–1088.
CLINICAL AND HUMAN IMMUNOLOGY
Bacillus Calmette–Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses
Sara Suliman; Hennie Geldenhuys; John L. Johnson; Jane E. Hughes; Erica Smit; Melissa Murphy; Asma Toefy; Lesedi Lerumo; Christiaan Hopley; Bernadette Pienaar; Phalkun Chheng; Elisa Nemes; Daniel F. Hoft; Willem A. Hanekom; W. Henry Boom; Mark Hatherill; Thomas J. Scriba
J Immunol (2016) 197 (4): 1100–1110.
Features of Human CD3+CD20+ T Cells
Elisabeth Schuh; Kerstin Berer; Matthias Mulazzani; Katharina Feil; Ingrid Meinl; Harald Lahm; Markus Krane; Rüdiger Lange; Kristina Pfannes; Marion Subklewe; Robert Gürkov; Monika Bradl; Reinhard Hohlfeld; Tania Kümpfel; Edgar Meinl; Markus Krumbholz
J Immunol (2016) 197 (4): 1111–1117.
IMMUNE REGULATION
A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells
J Immunol (2016) 197 (4): 1137–1147.
Effect of Anti–IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques
Maren Q. DeGottardi; Afam A. Okoye; Mukta Vaidya; Aarthi Talla; Audrie L. Konfe; Matthew D. Reyes; Joseph A. Clock; Derick M. Duell; Alfred W. Legasse; Amit Sabnis; Byung S. Park; Michael K. Axthelm; Jacob D. Estes; Keith A. Reiman; Rafick-Pierre Sekaly; Louis J. Picker
J Immunol (2016) 197 (4): 1183–1198.
IMMUNE SYSTEM DEVELOPMENT
IMMUNOGENETICS
The Minor MHC Class I Gene UDA of Ducks Is Regulated by Let-7 MicroRNA
J Immunol (2016) 197 (4): 1212–1220.
IMMUNOTHERAPY AND VACCINES
Integrated Nanovaccine with MicroRNA-148a Inhibition Reprograms Tumor-Associated Dendritic Cells by Modulating miR-148a/DNMT1/SOCS1 Axis
Lanlan Liu; Huqiang Yi; Ce Wang; Huamei He; Ping Li; Hong Pan; Nan Sheng; Manyi Ji; Lintao Cai; Yifan Ma
J Immunol (2016) 197 (4): 1231–1241.
INFECTIOUS DISEASE AND HOST RESPONSE
The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection
Sabriya Stukes; Carolina Coelho; Johanna Rivera; Anne E. Jedlicka; Katherine A. Hajjar; Arturo Casadevall
J Immunol (2016) 197 (4): 1252–1261.
INNATE IMMUNITY AND INFLAMMATION
Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation
Laura R. Hoyt; Jennifer L. Ather; Matthew J. Randall; Daniel P. DePuccio; Christopher C. Landry; Mark D. Wewers; Mikhail A. Gavrilin; Matthew E. Poynter
J Immunol (2016) 197 (4): 1322–1334.
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
J Immunol (2016) 197 (4): 1368–1378.
Identification of Evolutionarily Conserved Md1 Splice Variants That Regulate Innate Immunity through Differential Induction of NF-кB
J Immunol (2016) 197 (4): 1379–1388.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
Biophysical and Biochemical Characterization of Avian Secretory Component Provides Structural Insights into the Evolution of the Polymeric Ig Receptor
Beth M. Stadtmueller; Zhongyu Yang; Kathryn E. Huey-Tubman; Helena Roberts-Mataric; Wayne L. Hubbell; Pamela J. Bjorkman
J Immunol (2016) 197 (4): 1408–1414.
MUCOSAL IMMUNOLOGY
Early Epithelial Restitution by Nonsteroidal Anti-Inflammatory Drug–Activated Gene 1 Counteracts Intestinal Ulcerative Injuries
J Immunol (2016) 197 (4): 1415–1424.
G2A Signaling Dampens Colitic Inflammation via Production of IFN-γ
S. Courtney Frasch; Eóin N. McNamee; Douglas Kominsky; Paul Jedlicka; Claudia Jakubzick; Karin Zemski Berry; Matthias Mack; Glenn T. Furuta; James J. Lee; Peter M. Henson; Sean P. Colgan; Donna L. Bratton
J Immunol (2016) 197 (4): 1425–1434.
SYSTEMS IMMUNOLOGY
Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity
Matthew A. Care; Sophie J. Stephenson; Nicholas A. Barnes; Im Fan; Alexandre Zougman; Yasser M. El-Sherbiny; Edward M. Vital; David R. Westhead; Reuben M. Tooze; Gina M. Doody
J Immunol (2016) 197 (4): 1447–1459.
TRANSPLANTATION
CD8+ Effector T Cell Migration to Pancreatic Islet Grafts Is Dependent on Cognate Antigen Presentation by Donor Graft Cells
Qianqian Zhang; Hehua Dai; Karim M. Yatim; Khodor Abou-Daya; Amanda L. Williams; Martin H. Oberbarnscheidt; Geoffrey Camirand; Christopher E. Rudd; Fadi G. Lakkis
J Immunol (2016) 197 (4): 1471–1476.
TUMOR IMMUNOLOGY
A Critical Role for CD200R Signaling in Limiting the Growth and Metastasis of CD200+ Melanoma
Jin-Qing Liu; Fatemeh Talebian; Lisha Wu; Zhihao Liu; Ming-Song Li; Laichu Wu; Jianmin Zhu; Joseph Markowitz; William E. Carson, III; Sujit Basu; Xue-Feng Bai
J Immunol (2016) 197 (4): 1489–1497.
NOVEL IMMUNOLOGICAL METHODS
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Cover Image
Cover Image
On the cover: Immunohistochemistry staining shows CXCR3+ T cells (red) markedly infiltrated in and around hair follicles from patient with alopecia areata. Dai, Z., L. Xing, J. Cerise, E. H. C. Wang, A. Jabbari, A. de Jong, L. Petukhova, A. M. Christiano, and R. Clynes. 2016. CXCR3 blockade inhibits T cell migration into the skin and prevents development of alopecia areata. J. Immunol. 197: 1089–1099.
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