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Issues
1 March 2017
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells
Kangning Zhang; Xingyuan Xu; Muhammad Asghar Pasha; Christian W. Siebel; Angelica Costello; Angela Haczku; Katherine MacNamara; Tingbo Liang; Jinfang Zhu; Avinash Bhandoola; Ivan Maillard; Qi Yang
J Immunol (2017) 198 (5): 1798–1803.
ALLERGY AND OTHER HYPERSENSITIVITIES
Semaphorin 3E Deficiency Exacerbates Airway Inflammation, Hyperresponsiveness, and Remodeling in a Mouse Model of Allergic Asthma
J Immunol (2017) 198 (5): 1805–1814.
ANTIGEN RECOGNITION AND RESPONSES
Modulation of Naive CD8 T Cell Response Features by Ligand Density, Affinity, and Continued Signaling via Internalized TCRs
Renu Balyan; Rupali Gund; Chitra Ebenezer; Jasneet Kaur Khalsa; Divya Anna Verghese; Thyagarajan Krishnamurthy; Anna George; Vineeta Bal; Satyajit Rath; Ashutosh Chaudhry
J Immunol (2017) 198 (5): 1823–1837.
Gliadin-Specific CD8+ T Cell Responses Restricted by HLA Class I A*0101 and B*0801 Molecules in Celiac Disease Patients
Stefania Picascia; John Sidney; Alessandra Camarca; Giuseppe Mazzarella; Nicola Giardullo; Luigi Greco; Renata Auricchio; Salvatore Auricchio; Riccardo Troncone; Alessandro Sette; Carmen Gianfrani
J Immunol (2017) 198 (5): 1838–1845.
AUTOIMMUNITY
Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice
Yi Zhou; Huimei Chen; Li Liu; Xueqing Yu; Galina K. Sukhova; Min Yang; Vasileios C. Kyttaris; Isaac E. Stillman; Bruce Gelb; Peter Libby; George C. Tsokos; Guo-Ping Shi
J Immunol (2017) 198 (5): 1846–1854.
Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses
J Immunol (2017) 198 (5): 1855–1864.
CLINICAL AND HUMAN IMMUNOLOGY
Staphylococcus aureus Downregulates IP-10 Production and Prevents Th1 Cell Recruitment
J Immunol (2017) 198 (5): 1865–1874.
Human Dendritic Cell–Derived Induced Pluripotent Stem Cell Lines Are Not Immunogenic
J Immunol (2017) 198 (5): 1875–1886.
Mechanisms of Impaired Neutrophil Migration by MicroRNAs in Myelodysplastic Syndromes
Meiwan Cao; Yayoi Shikama; Hideo Kimura; Hideyoshi Noji; Kazuhiko Ikeda; Tomoyuki Ono; Kazuei Ogawa; Yasuchika Takeishi; Junko Kimura
J Immunol (2017) 198 (5): 1887–1899.
Amino Acid Catabolism in Multiple Sclerosis Affects Immune Homeostasis
J Immunol (2017) 198 (5): 1900–1909.
IMMUNE REGULATION
IMMUNE SYSTEM DEVELOPMENT
IMMUNOGENETICS
Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C
J Immunol (2017) 198 (5): 1961–1973.
INFECTIOUS DISEASE AND HOST RESPONSE
Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes
J Immunol (2017) 198 (5): 1974–1984.
Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia
Kaivon Assani; Chandra L. Shrestha; Frank Robledo-Avila; Murugesan V. Rajaram; Santiago Partida-Sanchez; Larry S. Schlesinger; Benjamin T. Kopp
J Immunol (2017) 198 (5): 1985–1994.
Induction of IL21 in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort
Lesley R. de Armas; Nicola Cotugno; Suresh Pallikkuth; Li Pan; Stefano Rinaldi; M. Celeste Sanchez; Louis Gonzalez; Alberto Cagigi; Paolo Rossi; Paolo Palma; Savita Pahwa
J Immunol (2017) 198 (5): 1995–2005.
The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8+ T Cells Present in the Liver
Alexandra J. Spencer; Rhea J. Longley; Anita Gola; Marta Ulaszewska; Teresa Lambe; Adrian V. S. Hill
J Immunol (2017) 198 (5): 2006–2016.
Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant αβ TCRs Specific for a Conserved Peptide–Qa-1b MHC Class Ib Ligand
J Immunol (2017) 198 (5): 2017–2027.
INNATE IMMUNITY AND INFLAMMATION
Circulating Monocytes Exhibit an Endotoxin Tolerance Status after Acute Ischemic Stroke: Mitochondrial DNA as a Putative Explanation for Poststroke Infections
Enrique Hernández-Jiménez; María Gutierrez-Fernández; Carolina Cubillos-Zapata; Laura Otero-Ortega; Berta Rodríguez-Frutos; Víctor Toledano; Patricia Martínez-Sánchez; Blanca Fuentes; Aníbal Varela-Serrano; José Avendaño-Ortiz; Alberto Blázquez; María Ángeles Mangas-Guijarro; Exuperio Díez-Tejedor; Eduardo López-Collazo
J Immunol (2017) 198 (5): 2038–2046.
Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice
Mathieu Nadeau-Vallée; Peck-Yin Chin; Lydia Belarbi; Marie-Ève Brien; Sheetal Pundir; Martin H. Berryer; Alexandra Beaudry-Richard; Ankush Madaan; David J. Sharkey; Alexis Lupien-Meilleur; Xin Hou; Christiane Quiniou; Alexandre Beaulac; Ines Boufaied; Amarilys Boudreault; Adriana Carbonaro; Ngoc-Duc Doan; Jean-Sebastien Joyal; William D. Lubell; David M. Olson; Sarah A. Robertson; Sylvie Girard; Sylvain Chemtob
J Immunol (2017) 198 (5): 2047–2062.
MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis
Víctor D. Cuevas; Laura Anta; Rafael Samaniego; Emmanuel Orta-Zavalza; Juan Vladimir de la Rosa; Geneviève Baujat; Ángeles Domínguez-Soto; Paloma Sánchez-Mateos; María M. Escribese; Antonio Castrillo; Valérie Cormier-Daire; Miguel A. Vega; Ángel L. Corbí
J Immunol (2017) 198 (5): 2070–2081.
Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders
J Immunol (2017) 198 (5): 2082–2092.
Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA
Jelka Pohar; Chikako Yamamoto; Ryutaro Fukui; Miša-Mojca Cajnko; Kensuke Miyake; Roman Jerala; Mojca Benčina
J Immunol (2017) 198 (5): 2093–2104.
Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9
Jillian P. Rhoads; John R. Lukens; Ashley J. Wilhelm; Jared L. Moore; Yanice Mendez-Fernandez; Thirumala-Devi Kanneganti; Amy S. Major
J Immunol (2017) 198 (5): 2105–2114.
CXCR3/CXCL10 Axis Regulates Neutrophil–NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis
Giorgia Benigni; Petya Dimitrova; Fabrizio Antonangeli; Emilio Sanseviero; Viktoriya Milanova; Arjen Blom; Peter van Lent; Stefania Morrone; Angela Santoni; Giovanni Bernardini
J Immunol (2017) 198 (5): 2115–2124.
Myeloid ATG16L1 Facilitates Host–Bacteria Interactions in Maintaining Intestinal Homeostasis
Hong Zhang; Libo Zheng; Dermot P. B. McGovern; Ariel M. Hamill; Ryan Ichikawa; Yoshitake Kanazawa; Justin Luu; Kotaro Kumagai; Marianne Cilluffo; Masayuki Fukata; Stephan R. Targan; David M. Underhill; Xiaolan Zhang; David Q. Shih
J Immunol (2017) 198 (5): 2133–2146.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
MUCOSAL IMMUNOLOGY
Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells
Gera Goverse; Rosalie Molenaar; Laurence Macia; Jian Tan; Martje N. Erkelens; Tanja Konijn; Marlene Knippenberg; Emma C. L. Cook; Diana Hanekamp; Marc Veldhoen; Anita Hartog; Guus Roeselers; Charles R. Mackay; Reina E. Mebius
J Immunol (2017) 198 (5): 2172–2181.
Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity
Maximilian W. Plank; Gerard E. Kaiko; Steven Maltby; Jessica Weaver; Hock L. Tay; Wei Shen; Mark S. Wilson; Scott K. Durum; Paul S. Foster
J Immunol (2017) 198 (5): 2182–2190.
SYSTEMS IMMUNOLOGY
NOVEL IMMUNOLOGICAL METHODS
A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data
J Immunol (2017) 198 (5): 2202–2210.
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Cover Image
Cover Image
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On the cover: Seasonal influenza vaccine responses in a pediatric cohort of HIV uninfected and HIV-infected individuals are visualized using a circos plot, in which colored ribbons represent serum Ab titer responses to each vaccine Ag (green, H1N1; blue, H3N2; red, B) and nodes within the black arcs represent individual participants. de Armas, L. R., N. Cotugno, S. Pallikkuth, L. Pan, S. Rinaldi, M. C. Sanchez, L. Gonzalez, A. Cagigi, P. Rossi, P. Palma, and S. Pahwa. 2017. Induction of IL21 in peripheral T follicular helper cells is an indicator of influenza vaccine response in a previously vaccinated HIV-infected pediatric cohort. J. Immunol. 198: 1995–2005.
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