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15 April 2017
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
BRIEF REVIEWS
CUTTING EDGE
Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate
Marina Miller; Arvin B. Tam; James L. Mueller; Peter Rosenthal; Andrew Beppu; Ruth Gordillo; Matthew D. McGeough; Christine Vuong; Taylor A. Doherty; Hal M. Hoffman; Maho Niwa; David H. Broide
J Immunol (2017) 198 (8): 3017–3022.
Cutting Edge: Innate Immune Augmenting Vesicular Stomatitis Virus Expressing Zika Virus Proteins Confers Protective Immunity
J Immunol (2017) 198 (8): 3023–3028.
ALLERGY AND OTHER HYPERSENSITIVITIES
ANTIGEN RECOGNITION AND RESPONSES
Novel Pattern Recognition Receptor Protects Shrimp by Preventing Bacterial Colonization and Promoting Phagocytosis
J Immunol (2017) 198 (8): 3045–3057.
Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling
Marjolein J. W. de Bruijn; Jasper Rip; Esmee K. van der Ploeg; Lars W. van Greuningen; Van T. B. Ta; Laurens P. Kil; Anton W. Langerak; Guus F. Rimmelzwaan; Wilfried Ellmeier; Rudi W. Hendriks; Odilia B. J. Corneth
J Immunol (2017) 198 (8): 3058–3068.
CLINICAL AND HUMAN IMMUNOLOGY
Dimethyl Fumarate Selectively Reduces Memory T Cells and Shifts the Balance between Th1/Th17 and Th2 in Multiple Sclerosis Patients
J Immunol (2017) 198 (8): 3069–3080.
IMMUNE REGULATION
Binding of Platelets to Lymphocytes: A Potential Anti-Inflammatory Therapy in Rheumatoid Arthritis
Carlos Zamora; Elisabet Cantó; Juan C. Nieto; Jorge Bardina; Cesar Diaz-Torné; Patricia Moya; Berta Magallares; M. Angels Ortiz; Germà Julià; Candido Juarez; Josep M. Llobet; Silvia Vidal
J Immunol (2017) 198 (8): 3099–3108.
Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism
Lars-Oliver Tykocinski; Anna M. Lauffer; Antonia Bohnen; Nathalie-Christin Kaul; Stefan Krienke; Theresa Tretter; Isabell Adam; Soumya R. Mohapatra; Philippe Saikali; Max Löhning; Michel Neidhart; Steffen Gay; Iris Oezen; Michael Platten; Christiane A. Opitz; Hanns-Martin Lorenz
J Immunol (2017) 198 (8): 3109–3117.
IMMUNE SYSTEM DEVELOPMENT
Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors
Jia Li; Sumedha Roy; Young-Mi Kim; Shibo Li; Baojun Zhang; Cassandra Love; Anupama Reddy; Deepthi Rajagopalan; Sandeep Dave; Anna Mae Diehl; Yuan Zhuang
J Immunol (2017) 198 (8): 3136–3148.
IMMUNOGENETICS
INFECTIOUS DISEASE AND HOST RESPONSE
Antiparasitic Treatment Induces an Improved CD8+ T Cell Response in Chronic Chagasic Patients
Jose Mateus; Elena Pérez-Antón; Paola Lasso; Adriana Egui; Nubia Roa; Bartolomé Carrilero; John M. González; M. Carmen Thomas; Concepción J. Puerta; Manuel C. López; Adriana Cuéllar
J Immunol (2017) 198 (8): 3170–3180.
Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
Jordan Ari Schwartz; Kiera L. Clayton; Shariq Mujib; Hongliang Zhang; A. K. M. Nur-ur Rahman; Jun Liu; Feng Yun Yue; Erika Benko; Colin Kovacs; Mario A. Ostrowski
J Immunol (2017) 198 (8): 3181–3194.
Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis
Qinqin Pu; Changpei Gan; Rongpeng Li; Yi Li; Shirui Tan; Xuefeng Li; Yuquan Wei; Lefu Lan; Xin Deng; Haihua Liang; Feng Ma; Min Wu
J Immunol (2017) 198 (8): 3205–3213.
Annexin A1 Is Involved in the Resolution of Inflammatory Responses during Leishmania braziliensis Infection
Leandro G. Oliveira; Míriam C. Souza-Testasicca; Juliana P. Vago; Amanda Braga Figueiredo; Adriana M. C. Canavaci; Luiza Oliveira Perucci; Tatiana P. Teixeira Ferreira; Eduardo A. F. Coelho; Denise Utsch Gonçalves; Manoel Otávio C. Rocha; Patrícia M. R. e Silva; Cláudia N. Ferreira; Celso Queiroz-Junior; Lirlândia P. Sousa; Ana Paula Fernandes
J Immunol (2017) 198 (8): 3227–3236.
INNATE IMMUNITY AND INFLAMMATION
The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors
Caroline Turcotte; Simona Zarini; Stéphanie Jean; Cyril Martin; Robert C. Murphy; David Marsolais; Michel Laviolette; Marie-Renée Blanchet; Nicolas Flamand
J Immunol (2017) 198 (8): 3255–3263.
MicroRNA-3570 Modulates the NF-κB Pathway in Teleost Fish by Targeting MyD88
J Immunol (2017) 198 (8): 3274–3282.
PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism
Yi Sak Kim; Hye-Mi Lee; Jin Kyung Kim; Chul-Su Yang; Tae Sung Kim; Mingyu Jung; Hyo Sun Jin; Sup Kim; Jichan Jang; Goo Taeg Oh; Jin-Man Kim; Eun-Kyeong Jo
J Immunol (2017) 198 (8): 3283–3295.
Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity
Nirav G. Shah; Mohan E. Tulapurkar; Aparna Ramarathnam; Amanda Brophy; Ramon Martinez, III; Kellie Hom; Theresa Hodges; Ramin Samadani; Ishwar S. Singh; Alexander D. MacKerell, Jr.; Paul Shapiro; Jeffrey D. Hasday
J Immunol (2017) 198 (8): 3296–3306.
A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma
Aarti Shikotra; David F. Choy; Salman Siddiqui; Greer Arthur; Deepti R. Nagarkar; Guiquan Jia; Adam K. A. Wright; Chandra M. Ohri; Emma Doran; Claire A. Butler; Beverley Hargadon; Alexander R. Abbas; Janet Jackman; Lawren C. Wu; Liam G. Heaney; Joseph R. Arron; Peter Bradding
J Immunol (2017) 198 (8): 3307–3317.
Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery
Tor Espen Stav-Noraas; Reidunn J. Edelmann; Lars La Cour Poulsen; Olav Sundnes; Danh Phung; Axel M. Küchler; Fredrik Müller; Amine A. Kamen; Guttorm Haraldsen; Mari Kaarbø; Johanna Hol
J Immunol (2017) 198 (8): 3318–3325.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
MUCOSAL IMMUNOLOGY
SYSTEMS IMMUNOLOGY
Systematic Analysis of Cell-Type Differences in the Epithelial Secretome Reveals Insights into the Pathogenesis of Respiratory Syncytial Virus–Induced Lower Respiratory Tract Infections
Yingxin Zhao; Mohammad Jamaluddin; Yueqing Zhang; Hong Sun; Teodora Ivanciuc; Roberto P. Garofalo; Allan R. Brasier
J Immunol (2017) 198 (8): 3345–3364.
CORRECTIONS
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Cover Image
Cover Image
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On the cover: Overall deuterium uptake differences between C3b and iC3b, as measured by mass spectrometry and mapped on the C3b structure. Cleavage of C3f (green segment) during the formation of iC3b results in significantly higher deuterium content (red shaded regions) compared to C3b, revealing a more dynamic and solvent-exposed conformation. Papanastasiou, M., S. Koutsogiannaki, Y. Sarigiannis, B. V. Geisbrecht, D. Ricklin, and J. D. Lambris. 2017. Structural implications for the formation and function of the complement effector protein iC3b. J. Immunol. 198: 3326–3335.
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