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Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis
Sarah J. Kane; Taylor K. Farley; Elizabeth O. Gordon; Joshua Estep; Heather R. Bender; Julie A. Moreno; Jason Bartz; Glenn C. Telling; Matthew C. Pickering; Mark D. Zabel
J Immunol (2017) 199 (11): 3821–3827.
Anti-CD20 Antibody Prevents Red Blood Cell Alloimmunization in a Mouse Model
Rahma Elayeb; Marie Tamagne; Marion Pinheiro; Julie Ripa; Rachid Djoudi; Philippe Bierling; France Pirenne; Benoît Vingert
J Immunol (2017) 199 (11): 3771–3780.
Cutting Edge: Anti–TIM-3 Treatment Exacerbates Pulmonary Inflammation and Fibrosis in Mice
Takuma Isshiki; Hisaya Akiba; Masafumi Nakayama; Norihiro Harada; Ko Okumura; Sakae Homma; Sachiko Miyake
J Immunol (2017) 199 (11): 3733–3737.
Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN
K. Michael Pollard; Gabriela M. Escalante; Hua Huang; Katarina M. Haraldsson; Per Hultman; Joseph M. Christy; Rahul D. Pawar; Jessica M. Mayeux; Rosana Gonzalez-Quintial; Roberto Baccala; Bruce Beutler; Argyrios N. Theofilopoulos; Dwight H. Kono
J Immunol (2017) 199 (11): 3739–3747.
IFN-λ4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling
Adeola A. Obajemu; Nina Rao; Kari A. Dilley; Joselin M. Vargas; Faruk Sheikh; Raymond P. Donnelly; Reed S. Shabman; Eric G. Meissner; Ludmila Prokunina-Olsson; Olusegun O. Onabajo
J Immunol (2017) 199 (11): 3808–3820.
IL-17A–Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
Jarod A. Zepp; Junjie Zhao; Caini Liu; Katazyna Bulek; Ling Wu; Xing Chen; Yujun Hao; Zhenghe Wang; Xinxin Wang; Wenjun Ouyang; Matthew F. Kalady; Julie Carman; Wen-Pin Yang; Jun Zhu; Clare Blackburn; Yina H. Huang; Thomas A. Hamilton; Bing Su; Xiaoxia Li
J Immunol (2017) 199 (11): 3849–3857.
Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy
Qiming Wang; Jeremy J. Racine; Jeremy J. Ratiu; Shu Wang; Rachel Ettinger; Clive Wasserfall; Mark A. Atkinson; David V. Serreze
J Immunol (2017) 199 (11): 3757–3770.
Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNA-Binding Protein Syncrip
Smita Kulkarni; Veron Ramsuran; Marijana Rucevic; Sukhvinder Singh; Alexandra Lied; Viraj Kulkarni; Colm O’hUigin; Sylvie Le Gall; Mary Carrington
J Immunol (2017) 199 (11): 3892–3899.
The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech
Siew Siew Pang; Lakshmi C. Wijeyewickrema; Lilian Hor; Sheareen Tan; Emilie Lameignere; Edward M. Conway; Anna M. Blom; Frida C. Mohlin; Xuyu Liu; Richard J. Payne; James C. Whisstock; Robert N. Pike
J Immunol (2017) 199 (11): 3883–3891.
Listeria monocytogenes Replicate in Bone Marrow–Derived CD11c+ Cells but Not in Dendritic Cells Isolated from the Murine Gastrointestinal Tract
J Immunol (2017) 199 (11): 3789–3797.
Orchestrating Role of Apoptosis Inhibitor of Macrophage in the Resolution of Acute Lung Injury
Hiroki Kimura; Masaru Suzuki; Satoshi Konno; Hideo Shindou; Takao Shimizu; Takahide Nagase; Toru Miyazaki; Masaharu Nishimura
J Immunol (2017) 199 (11): 3870–3882.
Innate Immune Activation by cGMP-AMP Nanoparticles Leads to Potent and Long-Acting Antiretroviral Response against HIV-1
J Immunol (2017) 199 (11): 3840–3848.
Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis
Katherine R. Martin; Magali Pederzoli-Ribeil; Emeline Pacreau; Sabrina S. Burgener; Albert Dahdah; Céline Candalh; Evelyne Lauret; Marc Foretz; Luc Mouthon; Bruno Lucas; Nathalie Thieblemont; Charaf Benarafa; Pierre Launay; Véronique Witko-Sarsat
J Immunol (2017) 199 (11): 3914–3924.
γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations
Irfan Zaidi; Hama Diallo; Solomon Conteh; Yvette Robbins; Jacqueline Kolasny; Sachy Orr-Gonzalez; Dariyen Carter; Brandi Butler; Lynn Lambert; Elizabeth Brickley; Robert Morrison; Mahamadou Sissoko; Sara A. Healy; B. Kim Lee Sim; Ogobara K. Doumbo; Stephen L. Hoffman; Patrick E. Duffy
J Immunol (2017) 199 (11): 3781–3788.
Infection of Ferrets with Influenza Virus Elicits a Light Chain–Biased Antibody Response against Hemagglutinin
J Immunol (2017) 199 (11): 3798–3807.
Pillars Article: Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function. Science. 1997. 275: 540–543
Hans-Willi Mittrücker; Toshifumi Matsuyama; Alex Grossman; Thomas M. Kündig; Julia Potter; Arda Shahinian; Andrew Wakeham; Bruce Patterson; Pamela S. Ohashi; Tak W. Mak
J Immunol (2017) 199 (11): 3717–3720.
Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis
Laurent Serre; Maeva Girard; Abdoulraouf Ramadan; Paul Menut; Nelly Rouquié; Liliana E. Lucca; Karim Mahiddine; Bertrand Leobon; Lennart T. Mars; Sylvie Guerder
J Immunol (2017) 199 (11): 3748–3756.
CK12a, a CCL19-like Chemokine That Orchestrates both Nasal and Systemic Antiviral Immune Responses in Rainbow Trout
J Immunol (2017) 199 (11): 3900–3913.
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Cover Image
Cover Image
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On the cover: Overview of the complex between the complement initiating protease, C1s, and a leech inhibitor, gigastasin. The C1s protease domain is shown as an electrostatic surface map, with gigastasin shown in gray. The leech inhibitor binds at three sites on the enzyme, including the active site. Pang, S. S., L. C. Wijeyewickrema, L. Hor, S. Tan, E. Lameignere, E. M. Conway, A. M. Blom, F. C. Mohlin, X. Liu, R. J. Payne, J. C. Whisstock, and R. N. Pike. 2017. The structural basis for complement inhibition by gigastasin, a protease inhibitor from the giant Amazon leech. J. Immunol. 199: 3883–3891.
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