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Issues
1 November 2017
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
PILLARS OF IMMUNOLOGY
ANTIGEN RECOGNITION AND RESPONSES
AUTOIMMUNITY
Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice
Daniele Sorcini; Stefano Bruscoli; Tiziana Frammartino; Monica Cimino; Emanuela Mazzon; Maria Galuppo; Placido Bramanti; Mumna Al-Banchaabouchi; Dominika Farley; Olga Ermakova; Olga Britanova; Mark Izraelson; Dmitry Chudakov; Michele Biagioli; Paolo Sportoletti; Sara Flamini; Marcello Raspa; Ferdinando Scavizzi; Claus Nerlov; Graziella Migliorati; Carlo Riccardi; Oxana Bereshchenko
J Immunol (2017) 199 (9): 3031–3041.
Pathogenic Role for γδ T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis
Poh-Yi Gan; Takeshi Fujita; Joshua Daniel Ooi; Maliha Asghar Alikhan; Jonathan Dick; Raymond Shim; Dragana Odobasic; Kim Maree O’Sullivan; Arthur Richard Kitching; Stephen Roger Holdsworth
J Immunol (2017) 199 (9): 3042–3050.
NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property
Chang-Suk Chae; Gi-Cheon Kim; Eun Sil Park; Choong-Gu Lee; Ravi Verma; Hagg-Lim Cho; Chang-Duk Jun; Yung Joon Yoo; Sin-Hyeog Im
J Immunol (2017) 199 (9): 3051–3062.
SHIP-1 Deficiency in AID+ B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity
Yingjia Chen; Fanlei Hu; Xuejiao Dong; Meng Zhao; Jing Wang; Xiaolin Sun; Tae Jin Kim; Zhanguo Li; Wanli Liu
J Immunol (2017) 199 (9): 3063–3073.
CLINICAL AND HUMAN IMMUNOLOGY
Basic Fibroblast Growth Factor 2 Is a Determinant of CD4 T Cell–Airway Smooth Muscle Cell Communication through Membrane Conduits
Soroor Farahnak; Toby K. McGovern; Rachael Kim; Michael O’Sullivan; Brian Chen; Minhyoung Lee; Haruka Yoshie; Anna Wang; Joyce Jang; Saba Al Heialy; Anne-Marie Lauzon; James G. Martin
J Immunol (2017) 199 (9): 3086–3093.
IMMUNE REGULATION
Myeloid-Derived Suppressor Cells Inhibit T Follicular Helper Cell Immune Response in Japanese Encephalitis Virus Infection
Chong Wang; Nan Zhang; Luting Qi; Jiaolong Yuan; Ke Wang; Kunlun Wang; Sicong Ma; Haili Wang; Wenjuan Lou; Pingdong Hu; Muhammad Awais; Shengbo Cao; Zhen F. Fu; Min Cui
J Immunol (2017) 199 (9): 3094–3105.
Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model
Kyle J. Bednar; Elena Shanina; Romain Ballet; Edward P. Connors; Shiteng Duan; Joana Juan; Britni M. Arlian; Michael D. Kulis; Eugene C. Butcher; Wai-Ping Fung-Leung; Tadimeti S. Rao; James C. Paulson; Matthew S. Macauley
J Immunol (2017) 199 (9): 3116–3128.
IL-17–Secreting γδ T Cells Are Completely Dependent upon CCR6 for Homing to Inflamed Skin
James J. Campbell; Karen Ebsworth; Linda S. Ertl; Jeffrey P. McMahon; Dale Newland; Yu Wang; Shirley Liu; Zhenhua Miao; Ton Dang; Penglie Zhang; Israel F. Charo; Rajinder Singh; Thomas J. Schall
J Immunol (2017) 199 (9): 3129–3136.
IMMUNE SYSTEM DEVELOPMENT
IMMUNOGENETICS
H3K27 Methylation Dynamics during CD4 T Cell Activation: Regulation of JAK/STAT and IL12RB2 Expression by JMJD3
J Immunol (2017) 199 (9): 3158–3175.
INFECTIOUS DISEASE AND HOST RESPONSE
Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria
Zhigang Li; Yang Jiao; Erica K. Fan; Melanie J. Scott; Yuehua Li; Song Li; Timothy R. Billiar; Mark A. Wilson; Xueyin Shi; Jie Fan
J Immunol (2017) 199 (9): 3176–3186.
Cytomegalovirus (CMV) Epitope–Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects
Chike O. Abana; Mark A. Pilkinton; Silvana Gaudieri; Abha Chopra; Wyatt J. McDonnell; Celestine Wanjalla; Louise Barnett; Rama Gangula; Cindy Hager; Dae K. Jung; Brian G. Engelhardt; Madan H. Jagasia; Paul Klenerman; Elizabeth J. Phillips; David M. Koelle; Spyros A. Kalams; Simon A. Mallal
J Immunol (2017) 199 (9): 3187–3201.
CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus Infection
J Immunol (2017) 199 (9): 3212–3221.
INNATE IMMUNITY AND INFLAMMATION
NEMO–IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS–STING Pathway
Run Fang; Chenguang Wang; Qifei Jiang; Mengze Lv; Pengfei Gao; Xiaoyu Yu; Ping Mu; Rui Zhang; Sheng Bi; Ji-Ming Feng; Zhengfan Jiang
J Immunol (2017) 199 (9): 3222–3233.
Monitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse
Christian M. Karsten; Anna V. Wiese; Fabian Mey; Julia Figge; Trent M. Woodruff; Tom Reuter; Olga Scurtu; Anna Kordowski; Larissa N. Almeida; Daria Briukhovetska; Katharina M. Quell; Jing Sun; Fanny Ender; Inken Schmudde; Tillman Vollbrandt; Yves Laumonnier; Jörg Köhl
J Immunol (2017) 199 (9): 3234–3248.
HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress
Maolin Ge; Zhen Luo; Zhi Qiao; Yao Zhou; Xin Cheng; Qibin Geng; Yanyan Cai; Pin Wan; Ying Xiong; Fang Liu; Kailang Wu; Yingle Liu; Jianguo Wu
J Immunol (2017) 199 (9): 3280–3292.
Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16–STING–Type I IFN Pathway and AIM2 Sensor
Fengliang Liu; Qingli Niu; Xiuzhen Fan; Connie Liu; Jie Zhang; Zhi Wei; Wei Hou; Thirumala-Devi Kanneganti; Merlin L. Robb; Jerome H. Kim; Nelson L. Michael; Jiaren Sun; Lynn Soong; Haitao Hu
J Immunol (2017) 199 (9): 3293–3305.
Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia–Reperfusion Injury
Ai Sadatomo; Yoshiyuki Inoue; Homare Ito; Tadayoshi Karasawa; Hiroaki Kimura; Sachiko Watanabe; Yoshiko Mizushina; Jun Nakamura; Ryo Kamata; Tadashi Kasahara; Hisanaga Horie; Naohiro Sata; Masafumi Takahashi
J Immunol (2017) 199 (9): 3306–3315.
MUCOSAL IMMUNOLOGY
Identification of IL-40, a Novel B Cell–Associated Cytokine
Jovani Catalan-Dibene; Monica I. Vazquez; Van Phi Luu; Sean-Paul Nuccio; Alborz Karimzadeh; Jenna M. Kastenschmidt; S. Armando Villalta; Irina Ushach; Egest J. Pone; Paolo Casali; Manuela Raffatellu; Amanda M. Burkhardt; Marcela Hernandez-Ruiz; Gina Heller; Peter A. Hevezi; Albert Zlotnik
J Immunol (2017) 199 (9): 3326–3335.
SYSTEMS IMMUNOLOGY
CD151 Expression Is Associated with a Hyperproliferative T Cell Phenotype
Lillian Seu; Christopher Tidwell; Laura Timares; Alexandra Duverger; Frederic H. Wagner; Paul A. Goepfert; Andrew O. Westfall; Steffanie Sabbaj; Olaf Kutsch
J Immunol (2017) 199 (9): 3336–3347.
TUMOR IMMUNOLOGY
PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8+ T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination
Arash Memarnejadian; Courtney E. Meilleur; Christopher R. Shaler; Khashayarsha Khazaie; Jack R. Bennink; Todd D. Schell; S. M. Mansour Haeryfar
J Immunol (2017) 199 (9): 3348–3359.
NOVEL IMMUNOLOGICAL METHODS
NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data
J Immunol (2017) 199 (9): 3360–3368.
CORRECTIONS
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Cover Image
Cover Image
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On the cover: Activated human CD4 T cells communicate with primary human airway smooth muscle cells via tube-like structures which are a continuum of the cell membrane, called lymphocyte-derived membrane conduits. Farahnak, S., T. K. McGovern, R. Kim, M. O'Sullivan, B. Chen, M. Lee, H. Yoshie, A. Wang, J. Jang, S. Al Heialy, A.-M. Lauzon, and J. G. Martin. 2017. Basic fibroblast growth factor 2 is a determinant of CD4 T cell–airway smooth muscle cell communication through membrane conduits. J. Immunol. 199: 3086–3093.
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